JPS5253866A - 3*55dichloroo44pyridonee11acetic acid preparation method - Google Patents

3*55dichloroo44pyridonee11acetic acid preparation method

Info

Publication number
JPS5253866A
JPS5253866A JP51108668A JP10866876A JPS5253866A JP S5253866 A JPS5253866 A JP S5253866A JP 51108668 A JP51108668 A JP 51108668A JP 10866876 A JP10866876 A JP 10866876A JP S5253866 A JPS5253866 A JP S5253866A
Authority
JP
Japan
Prior art keywords
acid preparation
preparation
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51108668A
Other languages
English (en)
Other versions
JPS614833B2 (ja
Inventor
Geerina Rorufu
Rogarusukii Berunaa
Berukuman Rorufu
Haamaisutaa Barutaa
Baariku Herumuuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2345402A external-priority patent/DE2345402C3/de
Priority claimed from DE19742427224 external-priority patent/DE2427224A1/de
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of JPS5253866A publication Critical patent/JPS5253866A/ja
Publication of JPS614833B2 publication Critical patent/JPS614833B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
JP51108668A 1973-09-08 1976-09-09 3*55dichloroo44pyridonee11acetic acid preparation method Granted JPS5253866A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2345402A DE2345402C3 (de) 1973-09-08 1973-09-08 7-( 1 ^-DihydnM-oxo-1 -pyridylacetamido)-cephemderivate und Verfahren zu ihrer Herstellung
DE19742427224 DE2427224A1 (de) 1974-06-06 1974-06-06 Cephemderivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
JPS5253866A true JPS5253866A (en) 1977-04-30
JPS614833B2 JPS614833B2 (ja) 1986-02-13

Family

ID=25765762

Family Applications (2)

Application Number Title Priority Date Filing Date
JP10341274A Expired JPS551274B2 (ja) 1973-09-08 1974-09-06
JP51108668A Granted JPS5253866A (en) 1973-09-08 1976-09-09 3*55dichloroo44pyridonee11acetic acid preparation method

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP10341274A Expired JPS551274B2 (ja) 1973-09-08 1974-09-06

Country Status (21)

Country Link
US (1) US4153693A (ja)
JP (2) JPS551274B2 (ja)
AR (3) AR205799A1 (ja)
CA (1) CA1072542A (ja)
CH (2) CH605993A5 (ja)
CY (1) CY970A (ja)
DD (1) DD114268A5 (ja)
DK (1) DK473974A (ja)
EG (1) EG11821A (ja)
ES (2) ES429864A1 (ja)
FR (1) FR2242987B1 (ja)
GB (1) GB1436989A (ja)
HK (1) HK62878A (ja)
IL (1) IL45488A (ja)
IT (1) IT1106059B (ja)
KE (1) KE2890A (ja)
MY (1) MY7800442A (ja)
NL (1) NL7411868A (ja)
NO (1) NO147754C (ja)
SE (1) SE433850B (ja)
YU (1) YU36182B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2507834A1 (de) * 1975-02-24 1976-09-02 Merck Patent Gmbh Cephemderivate und verfahren zu ihrer herstellung
JPS55153791A (en) * 1979-05-18 1980-11-29 Sumitomo Chem Co Ltd Novel beta-lactam compound
KR100841044B1 (ko) * 2002-01-15 2008-06-25 주식회사 엔지켐 세팔로스포린 화합물의 제조 방법
CN101584671B (zh) * 2009-07-17 2011-03-16 山东罗欣药业股份有限公司 一种头孢西酮钠药物粉针剂以及头孢西酮钠原料药的合成方法
CN104119361B (zh) * 2014-07-10 2015-07-29 山东罗欣药业集团股份有限公司 一种新型抗生素化合物的精制方法
CN104230958A (zh) * 2014-08-22 2014-12-24 赵明亮 一种头孢西酮的制备方法
CN106967092B (zh) * 2017-04-12 2019-05-03 山东裕欣药业有限公司 一种头孢西酮的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3218318A (en) * 1962-08-31 1965-11-16 Lilly Co Eli 7-heterocyclic-substituted-acylamido cephalosporins
US3833570A (en) * 1970-08-12 1974-09-03 Bristol Myers Co 7-(3-substituted-1,2,4-oxadiazole-5-one-4-acetamido)cephalosporanic acids and derivatives thereof
US3956287A (en) * 1973-11-07 1976-05-11 Richardson-Merrell Inc. 7-[(2-Oxo-1-pyridinyl)acylamino]cephalosporin derivatives
US3956288A (en) * 1973-11-07 1976-05-11 Richardson-Merrell Inc. 7-[(2,4-Dioxo-1-pyrimidinyl)acylamino]cephalosporin derivatives
US4119775A (en) * 1974-09-27 1978-10-10 Richardson-Merrell Inc. 4-Oxo-1-pyridinyl cephalosporin derivatives

Also Published As

Publication number Publication date
JPS5053392A (ja) 1975-05-12
NO147754B (no) 1983-02-28
ES442217A1 (es) 1977-07-01
YU36182B (en) 1982-02-25
KE2890A (en) 1978-10-27
SE7411162L (ja) 1975-03-10
ES429864A1 (es) 1977-01-01
MY7800442A (en) 1978-12-31
FR2242987A1 (ja) 1975-04-04
AR202261A1 (es) 1975-05-23
AR205799A1 (es) 1976-06-07
AU7243474A (en) 1976-02-19
DK473974A (ja) 1975-05-05
DD114268A5 (ja) 1975-07-20
JPS551274B2 (ja) 1980-01-12
CY970A (en) 1978-12-22
AR208079A1 (es) 1976-11-30
GB1436989A (en) 1976-05-26
EG11821A (en) 1977-12-31
CH605992A5 (ja) 1978-10-13
HK62878A (en) 1978-11-03
YU240474A (en) 1981-06-30
SE433850B (sv) 1984-06-18
FR2242987B1 (ja) 1977-11-04
IT7851703A0 (it) 1978-10-30
US4153693A (en) 1979-05-08
NL7411868A (nl) 1975-03-11
CH605993A5 (ja) 1978-10-13
NO743205L (ja) 1975-04-07
CA1072542A (en) 1980-02-26
NO147754C (no) 1983-06-08
JPS614833B2 (ja) 1986-02-13
IL45488A0 (en) 1974-11-29
IT1106059B (it) 1985-11-11
IL45488A (en) 1977-10-31

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