JPH1143427A - Bathing agent - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a bathing agent having inhibitory effects on proliferation of microorganisms in a bathtub and excellent safety, by including copper gluconate or zinc gluconate as a component for controlling the proliferation of microorganisms. SOLUTION: This bathing agent contains preferably 5-100 wt.% based on the preparation weight of at least one selected from copper gluconate and zinc gluconate as a component for controlling the proliferation of microorganisms and is applied to water in a bathtub so as to give 0.0005-0.1 wt.% concentration based on water in the bathtub. The bathing agent may be mixed with an inorganic salt (e.g. sodium sulfate, sodium chloride) and a component (e.g. Guinea pepper, camomile, SENNKYU (rhizome of Cnidium officinale) having heat installation, moisture retention and skin cleaning actions. The bathing agent can be prepared as a powdery aiticle only by formulating fixed amounts of the components and prepared as a solid form such as a fine granule article, a granulated article, a tablet and a shape of capsule agent.

Description

【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION

【０００１】[0001]

【発明の属する技術分野】本発明は浴用剤、より詳しく
は浴槽内での微生物の増殖を抑制する成分を含有する浴
用剤に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a bath preparation, and more particularly to a bath preparation containing a component for suppressing the growth of microorganisms in a bathtub.

【０００２】[0002]

【従来の技術】入浴剤（浴用剤）は、温浴効果、保温、
保湿作用、皮膚の清浄作用等を期待して、各種無機塩類
を中心に、生薬成分や各種エキス類等を添加配合して調
製され、実用されている。2. Description of the Related Art Bath additives (bath preparations) have a warm bath effect, heat retention,
With the expectation of a moisturizing effect, a cleansing effect on the skin, and the like, it is prepared by adding and blending herbal components and various extracts, mainly various inorganic salts, and is in practical use.

【０００３】一方、市場においては、病原性大腸菌によ
る食中毒等の問題や、２４時間風呂においてのレジオネ
ラ菌の増殖等の問題が生じるに至り、一般にも浴槽水を
清潔に保つ意識が高まってきており、かかる観点から、
浴槽水中で微生物の増殖を抑制乃至防止できる機能を併
せ持つ改良された浴用剤の開発が望まれている。[0003] On the other hand, in the market, problems such as food poisoning due to pathogenic Escherichia coli and problems such as growth of Legionella bacteria in a 24-hour bath have occurred, and in general, awareness of keeping bath water clean has been increasing. From this perspective,
It is desired to develop an improved bath agent having a function of suppressing or preventing the growth of microorganisms in bath water.

【０００４】しかるに、食品分野、医薬品分野における
微生物の増殖抑制には、従来より主として各種の抗菌剤
の利用が行なわれてきており、上記要望に合致する浴用
剤の開発には、かかる抗菌剤の配合が考えられるが、浴
用剤自体浴槽水に対して例えば１８０リットル当たり４
〜５０ｇ程度と少量しか配合されないものであり、これ
に配合する抗菌剤の量には制限があり、該配合によって
も充分な抗菌作用は発揮し難い。逆に、所望の抗菌作用
を発揮できる程度の多量の配合によれば、浴用剤自体の
剤形も問題となるばかりか、これに配合される抗菌剤の
ヒトに対する悪影響、例えば毒性、副作用、刺激性等も
問題となり、いずれにしても従来よく知られている抗菌
剤の利用によっては、浴槽内の微生物の増殖を抑制する
ことのできる浴用剤を得ることはできない現状にある。However, various antibacterial agents have been mainly used for suppressing the growth of microorganisms in the field of foods and pharmaceuticals, and the development of bathing agents meeting the above-mentioned demands requires the use of such antibacterial agents. The mixing can be considered, but the bath agent itself is, for example, 4 per 180 liters with respect to bath water.
Only a small amount of about 50 g is blended, and the amount of the antibacterial agent to be blended therewith is limited, and it is difficult to exert a sufficient antibacterial action even by the blending. Conversely, with a large amount of compounding agent that can exhibit the desired antibacterial action, not only does the formulation of the bath preparation itself become a problem, but also the antibacterial agent incorporated therein adversely affects humans, for example, toxicity, side effects, irritation In addition, there is also a problem with the properties and the like, and in any case, it is impossible to obtain a bath agent capable of suppressing the growth of microorganisms in a bathtub by using a conventionally well-known antibacterial agent.

【０００５】[0005]

【発明が解決しようとする課題】本発明者の目的は、上
記現状に鑑みて、浴槽内の微生物の増殖を抑制すること
ができ、しかも抗菌剤の配合に認められる如き悪影響を
伴わず、安全に利用することのできる新しい改良された
浴用剤を提供することにある。SUMMARY OF THE INVENTION In view of the above-mentioned circumstances, an object of the present inventor is to suppress the growth of microorganisms in a bathtub, and furthermore, without the adverse effects observed in the formulation of antibacterial agents, It is an object of the present invention to provide a new and improved bath agent which can be used for a bath.

【０００６】本発明者らは、上記目的より鋭意研究を重
ねた結果、グルコン酸銅及びグルコン酸亜鉛の配合が、
上記目的に合致する優れた効果を奏する浴用剤の提供を
可能とすることを見出し、ここに本発明を完成するに至
った。The inventors of the present invention have conducted intensive studies for the above purpose, and as a result, the compounding of copper gluconate and zinc gluconate has
The present inventors have found that it is possible to provide a bath agent exhibiting excellent effects meeting the above-mentioned objects, and have completed the present invention.

【０００７】[0007]

【課題を解決するための手段】即ち、本発明はグルコン
酸銅及びグルコン酸亜鉛から選ばれる少なくとも１種を
微生物増殖抑制成分として含有させたことを特徴とする
浴用剤、より詳しくは、微生物増殖抑制成分含量が製剤
重量の５〜１００重量％である上記浴用剤及び浴槽水当
たり０．０００５〜０．１％の濃度となるよう浴槽水に
適用される上記浴用剤に係わる。That is, the present invention relates to a bath agent comprising at least one selected from copper gluconate and zinc gluconate as a component for inhibiting the growth of microorganisms. The present invention relates to the above bath preparation having an inhibitory component content of 5 to 100% by weight of the preparation weight and the above bath preparation applied to bath water so as to have a concentration of 0.0005 to 0.1% per bath water.

【０００８】本発明の浴用剤は、上記グルコン酸銅及び
／又はグルコン酸亜鉛を配合したことに基づいて、優れ
た浴槽内微生物増殖抑制効果を奏し得、しかも安全性に
も優れており、勿論、浴用剤本来の効果は何等損なうこ
とはない。The bath preparation of the present invention, based on the addition of the above-mentioned copper gluconate and / or zinc gluconate, can exhibit an excellent effect of suppressing the growth of microorganisms in a bathtub, and is excellent in safety. The original effect of the bath agent is not impaired at all.

【０００９】[0009]

【発明の実施の形態】以下、本発明浴用剤につき詳述す
れば、これは従来公知の各種組成の浴用剤に微生物増殖
抑制成分として上記特定の化合物を添加配合することを
最大の特徴とし、これに基づいて、本発明所期の優れた
効果を奏し得る。BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, the bath agent of the present invention will be described in detail. It is characterized by adding the above-mentioned specific compound as a microorganism growth inhibiting component to a conventionally known bath agent of various compositions. Based on this, the desired excellent effects of the present invention can be obtained.

【００１０】上記微生物増殖抑制成分としてのグルコン
酸銅及びグルコン酸亜鉛としては、通常入手される各種
の形態、例えば粉末形態等のものをそのまま本発明に利
用することができる。As the above-mentioned components for inhibiting the growth of microorganisms, copper gluconate and zinc gluconate can be used in the present invention in various forms, such as powder forms, which are generally available.

【００１１】上記グルコン酸銅及びグルコン酸亜鉛の浴
用剤中への添加配合量は、通常５〜１００重量％、好ま
しくは２０〜５０重量％の範囲から選択されるのがよ
い。The amount of the above-mentioned copper gluconate and zinc gluconate added to the bath agent is generally selected from the range of 5 to 100% by weight, preferably 20 to 50% by weight.

【００１２】本発明浴用剤は、上記特定の微生物増殖抑
制成分の添加配合を除いて他は、従来の各種浴用剤と同
様のものとすることができる。The bath preparation of the present invention can be the same as various conventional bath preparations except for the addition and blending of the specific microorganism growth inhibiting component.

【００１３】即ち、浴用剤ベース成分としての無機塩類
としては、例えば硫酸ナトリウム、塩化ナトリウム、ホ
ウ酸 炭酸ナトリウム、炭酸カリウム等を例示できる。That is, examples of the inorganic salts as a base material for a bath agent include sodium sulfate, sodium chloride, sodium borate, potassium carbonate and the like.

【００１４】これに配合される保温、保湿、皮膚清浄作
用等を奏し得る成分としては、例えばトウガラシ、カミ
ツレ、センキュウ、トウキ、ケイヒ、ハマボウフウ、ハ
ッカ、ゴシュウ、トウヒ、ユズ、クスノキ、ケイガイ、
ショウブ等の生薬成分や海藻エキス等の各種エキス類を
例示することができる。Examples of the components capable of exhibiting heat retention, moisture retention, skin cleansing, and the like incorporated therein include, for example, pepper, chamomile, senkyu, touki, cinnamon, hamabou, mint, goshu, spruce, yuzu, camphor, kaygai,
Examples thereof include crude drug components such as shobu and various extracts such as seaweed extract.

【００１５】上記ベース成分、生薬成分等は、一般的処
方に従って、例えばベース成分９０〜９９．９重量％、
生薬成分０．１〜１０重量％程度の範囲から適宜決定さ
れる量で用いることができる。The above base component, crude drug component, etc. are, for example, 90 to 99.9% by weight of the base component,
The crude drug component can be used in an amount appropriately determined from the range of about 0.1 to 10% by weight.

【００１６】本発明浴用剤は、上記各成分の所定量を単
に混合（配合）するだけで容易に粉末品として調製する
ことができ、また適当な賦形剤等を用いて適宜賦形して
細粒品、造粒品、錠剤等の適当な固剤形態や之等を含む
カプセル剤形態に調製することもでき、更に適当な希釈
剤、溶解剤、乳化剤等を利用して液剤形態に調製するこ
ともできる。之等各種形態への調製方法は、特に限定さ
れず、通常のこの種浴用剤と同様の各種一般的方法に従
うことができる。The bath agent of the present invention can be easily prepared as a powdery product simply by mixing (blending) a predetermined amount of each of the above-mentioned components, and may be appropriately shaped using an appropriate excipient or the like. It can be prepared into a suitable solid form such as fine granules, granules, tablets, etc., or into a capsule form containing the same, and further prepared into a liquid form using a suitable diluent, solubilizer, emulsifier, etc. You can also. The method of preparing these various forms is not particularly limited, and various general methods similar to those of ordinary bath agents can be used.

【００１７】本発明浴用剤は、上記必須成分の他に、更
に必要に応じてこの種浴用剤に使用できることの知られ
ている他の薬効成分や各種の添加剤を添加配合すること
もできる。上記薬効成分としては、例えばサリチル酸メ
チル、アロエエキス、カンゾウエキス等の消炎剤成分や
メントール等の清涼剤成分を例示できる。他の添加剤と
しては、パラオキシ安息香酸メチル、パラオキシ安息香
酸プロピル等の保存剤、ＥＤＴＡ等の水質改善剤、香料
着色料、発泡成分等を例示できる。In addition to the above essential components, the bath agent of the present invention may further contain, if necessary, other medicinal components and various additives which are known to be usable in this type of bath agent. Examples of the medicinal component include an anti-inflammatory component such as methyl salicylate, aloe extract and licorice extract, and a cooling agent component such as menthol. Examples of the other additives include preservatives such as methyl paraoxybenzoate and propyl paraoxybenzoate, water quality improvers such as EDTA, flavor coloring agents, foaming components, and the like.

【００１８】かくして得られる本発明の浴用剤は、通常
のこの種浴用剤と同様にしてこれを浴槽に適用できる。
その適用量は、一般には本発明製剤の総量が、湯２００
リットル当り約４〜１００ｇ程度の範囲となる量を目安
とすることができる。従って、本発明浴用剤中の微生物
増殖抑制成分は、湯２００リットル当たり約０．８〜５
０ｇ／ｌ程度、即ち約４〜２５０ｍｇ／ｌ（ｐｐｍ）程
度となる量を目安とすることができる。The bath preparation of the present invention thus obtained can be applied to a bath tub in the same manner as ordinary bath preparations of this kind.
In general, the total amount of the preparation of the present invention is 200
An amount in the range of about 4 to 100 g per liter can be used as a guide. Therefore, the microbial growth inhibitory component in the bath agent of the present invention is about 0.8 to 5 per 200 liters of hot water.
The amount may be about 0 g / l, that is, about 4 to 250 mg / l (ppm).

【００１９】本発明浴用剤によって、その増殖を抑制乃
至防止できる微生物には、レジオネラ菌、緑膿菌等が包
含される。Microorganisms whose growth can be suppressed or prevented by the bath agent of the present invention include Legionella bacteria and Pseudomonas aeruginosa.

【００２０】[0020]

【発明の効果】本発明浴用剤は、グルコン酸銅及びグル
コン酸亜鉛から選ばれる少なくとも１種の添加配合に基
づいて、従来例のない優れた微生物増殖抑制効果を奏し
得、安全性に優れるものである。The bath agent of the present invention, based on at least one additive selected from copper gluconate and zinc gluconate, can exhibit an unprecedented excellent microbial growth inhibitory effect and is excellent in safety. It is.

【００２１】[0021]

【実施例】以下、本発明を更に詳しく説明するため、本
発明浴用剤の製造例を実施例として挙げ、次いでその適
用による効果を明らかとする試験例を挙げる。EXAMPLES Hereinafter, in order to explain the present invention in more detail, a production example of the bath agent of the present invention will be described as an example, and then a test example for clarifying the effect of its application will be described.

【００２２】[0022]

【実施例１〜４】グルコン酸銅又はグルコン酸亜鉛を含
む表１に示す各成分のそれぞれ所定量を混合し、またそ
の後打錠して、本発明浴用剤（粉末及び錠剤）のそれぞ
れを調製した。Examples 1 to 4 Each of the components shown in Table 1 containing copper gluconate or zinc gluconate was mixed in a predetermined amount and then tableted to prepare each of the bath agents (powder and tablet) of the present invention. did.

【００２３】[0023]

【比較例１及び２】表１に示す各成分（グルコン酸銅及
びグルコン酸亜鉛を含まず、その分硫酸ナトリウムを増
目した）のそれぞれ所定量を用いて、実施例と同様にし
て比較浴用剤（粉末及び錠剤）を調製した。Comparative Examples 1 and 2 A comparative bath was prepared in the same manner as in Example by using a predetermined amount of each of the components shown in Table 1 (not including copper gluconate and zinc gluconate and increasing the amount of sodium sulfate accordingly). Agents (powder and tablets) were prepared.

【００２４】[0024]

【表１】 [Table 1]

【００２５】[0025]

【試験例１】実施例１及び２並びに比較例１で調製した
各浴用剤試料（錠剤）の１錠（４ｇ）を、一般家庭用浴
槽（約１８０リットル）の湯に添加し、一般家庭を想定
して、該湯に４時間で合計４人（１人当たりの入浴時間
は平均２０分）の入浴を行なわせた。尚、上記試験時間
中、湯温は平均４０±２℃に維持し、その後は自然放冷
させた。Test Example 1 One tablet (4 g) of each bath preparation sample (tablet) prepared in Examples 1 and 2 and Comparative Example 1 was added to hot water in a general household bathtub (about 180 liters), and a general household was prepared. Assuming that the bath was bathed in the hot water for a total of four people in four hours (the bathing time per person was an average of 20 minutes). During the test period, the temperature of the hot water was maintained at an average of 40 ± 2 ° C., and thereafter, it was allowed to cool naturally.

【００２６】上記試験時間の経過１２時間後に、浴槽水
の手による触感（ぬめり感）を、１０名のパネラーによ
り評価させると共に、一般生菌数を調べた。Twelve hours after the elapse of the test time, the hand feel (sliminess) of the bathtub water was evaluated by 10 panelists, and the number of general viable bacteria was examined.

【００２７】ぬめり感の評価は、下記基準に従った。The evaluation of the sliminess was based on the following criteria.

【００２８】 −…１０人全員がぬめり感を認めない ＋…１０人中５人までがぬめり感を認めた ＋＋…１０人中５人以上がぬめり感を認めた また、一般生菌数の測定は、日本薬局方の微生物限度試
験法、寒天平板表面塗抹法に従い、ソイビーン・カゼイ
ン・ダイジェスト寒天培地を用いて、次の通り行なっ
た。即ち、定時に採取した浴槽水１ｍｌを直ちに生理食
塩水にて、１０倍、１００倍及び１０００倍に希釈し、
この希釈液０．１ｍｌを培地に均一に塗布し、３０〜３
５℃で５日間培養し、現われたコロニー数より希釈液１
ｍｌ当たりの一般生菌数を換算して求めた。-: All 10 persons did not feel slimy. +: Up to 5 persons felt slimy. ++ ... 5 or more persons recognized slimy. Was carried out as follows using a soybean casein digest agar medium in accordance with the microorganism limit test method and the agar plate surface smear method of the Japanese Pharmacopoeia. That is, 1 ml of bath water collected at regular intervals was immediately diluted 10 times, 100 times and 1000 times with physiological saline,
0.1 ml of this diluted solution is uniformly applied to the medium, and 30 to 3
After culturing at 5 ° C for 5 days, diluent 1
The number of general viable bacteria per ml was calculated and calculated.

【００２９】結果を下記表２に示す。尚、表２には浴用
剤試料無添加の浴槽における同試験結果を併記する。The results are shown in Table 2 below. Table 2 also shows the results of the test in a bathtub without a bath agent sample.

【００３０】[0030]

【表２】 [Table 2]

【００３１】上記表２より、本発明浴用剤の利用によれ
ば、ぬめり感もなく、一般生菌数を顕著に抑制できるこ
とが判る。From Table 2 above, it can be seen that the use of the bath agent of the present invention can significantly suppress the number of general viable bacteria without sliminess.

【００３２】[0032]

【試験例２】実施例３及び４並びに比較例２で調製した
各浴用剤試料（粉末）の１包（４０ｇ）を、一般家庭用
浴槽（約１８０リットル）の湯に添加し、一般家庭を想
定して、該湯に４時間で合計４人（１人当たりの入浴時
間は平均２０分）の入浴を行なわせた。尚、湯温は平均
４２±１℃に維持（試験開始後４８時間まで）した。Test Example 2 One packet (40 g) of each bath preparation sample (powder) prepared in Examples 3 and 4 and Comparative Example 2 was added to hot water in a general household bathtub (about 180 liters), Assuming that the bath was bathed in the hot water for a total of four people in four hours (the bathing time per person was an average of 20 minutes). The hot water temperature was maintained at an average of 42 ± 1 ° C. (until 48 hours after the start of the test).

【００３３】上記試験時間の経過２４時間後及び４８時
間後に、浴槽水の手による触感（ぬめり感）及び一般生
菌数を試験例１と同様にして評価、測定した。At 24 hours and 48 hours after the elapse of the test time, the hand feel (sliminess) of the bath water and the number of general viable bacteria were evaluated and measured in the same manner as in Test Example 1.

【００３４】結果を下記表３に示す。尚、表３には浴用
剤試料無添加の浴槽における同試験結果を併記する。The results are shown in Table 3 below. Table 3 also shows the results of the test in a bathtub without a bath agent sample added.

【００３５】[0035]

【表３】 [Table 3]

【００３６】上記表３より、本発明浴用剤の利用によれ
ば、ぬめり感もなく、一般生菌数を顕著に抑制できるこ
とが判る。From Table 3 above, it can be seen that the use of the bath agent of the present invention makes it possible to remarkably suppress the general viable cell count without sliminess.

Claims (3)

【特許請求の範囲】[Claims] 【請求項１】グルコン酸銅及びグルコン酸亜鉛から選ば
れる少なくとも１種を微生物増殖抑制成分として含有さ
せたことを特徴とする浴用剤。1. A bath preparation comprising at least one selected from copper gluconate and zinc gluconate as a component for inhibiting the growth of microorganisms. 【請求項２】微生物増殖抑制成分含量が製剤重量の５〜
１００重量％である請求項１に記載の浴用剤。2. The microorganism growth inhibitory component content is 5 to 5 parts by weight of the preparation.
The bath agent according to claim 1, which is 100% by weight. 【請求項３】浴槽水当たり０．０００５〜０．１％の濃
度となるよう浴槽水に適用される請求項１又は２に記載
の浴用剤。3. The bath preparation according to claim 1, which is applied to the bathtub water so as to have a concentration of 0.0005 to 0.1% per bathtub water.