JPH10218731A - Preparation for external use for skin treatment after depilation treatment - Google Patents
Preparation for external use for skin treatment after depilation treatmentInfo
- Publication number
- JPH10218731A JPH10218731A JP6371197A JP6371197A JPH10218731A JP H10218731 A JPH10218731 A JP H10218731A JP 6371197 A JP6371197 A JP 6371197A JP 6371197 A JP6371197 A JP 6371197A JP H10218731 A JPH10218731 A JP H10218731A
- Authority
- JP
- Japan
- Prior art keywords
- treatment
- skin
- linolenic acid
- hair removal
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
Description
【０００１】[0001]
【産業上の利用分野】この発明は、脱毛処理後の皮膚ト
リートメントに関し、脱毛処理後の皮膚障害を速やかに
改善する皮膚トリートメント外用剤に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a skin treatment after a hair removal treatment, and more particularly to an external preparation for a skin treatment which rapidly improves skin damage after the hair removal treatment.
【０００２】[0002]
【従来の技術】近年、美容の分野に大きな変化をもたら
したものに脱毛があり、今日ではエステティックの一部
門として極めて大きな位置を占めるまでになった。2. Description of the Related Art In recent years, hair loss has been one of the major changes in the field of beauty, and has now become a very large division of aesthetics.
【０００３】脱毛のなかで永久脱毛法とされているのに
電気脱毛法がある。これは、例えば毛包内にニードルを
挿入し、直流電流及び／又は高周波電流をニードルを通
じて毛包内に通電することにより、毛母細胞を加熱及び
／又はアルカリ変性させることにより永久脱毛するもの
である。[0003] Among the hair removal methods, the permanent hair removal method is the electric hair removal method. For example, by inserting a needle into the hair follicle and applying a direct current and / or a high-frequency current to the hair follicle through the needle, the hair is permanently depilated by heating and / or denaturing the hair mother cell. is there.
【０００４】しかるに、電気脱毛法では高周波加熱によ
る熱傷及び／又はアルカリ変性によるアルカリによって
炎症状態が生じ、毛包の周囲の皮膚が障害され、皮膚表
面に赤斑状の傷痕や、かぶれなどが生じるという問題が
ある。[0004] However, in the electric hair removal method, a burn due to high frequency heating and / or an alkali due to alkali denaturation causes an inflammatory condition, which damages the skin around the hair follicle and causes a red-spotted scar or rash on the skin surface. There's a problem.
【０００５】また、この永久脱毛法に対して一時的脱毛
法があり、例えばかみそりで剃る、毛抜きで抜く、脱毛
ワックスの使用、脱毛クリームの使用などの方法があ
る。しかしながら、この一時的脱毛法においても脱毛処
理による皮膚障害は免れず、例えばかみそりで剃る場合
には皮膚表面の剥離による肌荒れが、また毛抜きや脱毛
ワックスでは皮膚表面に鳥肌のようなブツブツが、さら
に脱毛クリームではアルカリ剤などの化学物質による皮
膚かぶれなどが生じる弊害がある。[0005] In addition to the permanent hair removal method, there is a temporary hair removal method, for example, a method of shaving with a razor, removing with a hair remover, using a hair removal wax, using a hair removal cream, or the like. However, even in this temporary hair removal method, skin damage due to hair removal treatment is inevitable, for example, when shaving with a razor, skin roughening due to peeling of the skin surface, and hair removal or hair removal wax, a bumpy skin like goose bumps on the skin surface, furthermore Depilatory creams have the problem of causing skin irritation and the like due to chemicals such as alkaline agents.
【０００６】このような脱毛処理後の皮膚障害は一時的
な急性炎症の一種と考えられ、できるだけ速やかに改善
することが肝要で、炎症状態が長引けば上記皮膚障害に
加え、例えば細菌感染による毛嚢炎や化膿性の炎症、色
素沈着などの不都合が生じ易くなる。[0006] Such a skin disorder after hair removal treatment is considered to be a kind of temporary acute inflammation, and it is important to improve it as soon as possible. If the inflammatory state is prolonged, in addition to the skin disorder, for example, hair due to bacterial infection Inconveniences such as cystitis, purulent inflammation, and pigmentation are likely to occur.
【０００７】また、脱毛処理後の皮膚障害は、例えばア
トピー体質に代表されるアレルギー疾患の人の場合に
は、正常皮膚の人に較べひどい皮膚障害が現れたり、元
の皮膚状態に回復するのに長時間を要するといった弊害
もある。さらに、一時的脱毛法においては言うまでもな
く、永久脱毛法においても通常完全に脱毛するには同じ
箇所を二、三回繰り返し処理する必要があり、一層脱毛
処理後の適切な皮膚ケアーが要求されている。[0007] The skin disorder after the hair removal treatment is, for example, in the case of a person with an allergic disease typified by atopic constitution, a severe skin disorder appears as compared to a person with normal skin, or the skin condition is restored to the original state. Also takes a long time. Furthermore, not only in the temporary hair removal method but also in the permanent hair removal method, it is usually necessary to repeatedly treat the same part a few times in order to completely remove the hair, and more appropriate skin care after the hair removal treatment is required. I have.
【０００８】そして、脱毛処理後に生じる皮膚障害のケ
アーとしては従来、ステロイド性抗炎症剤では副作用が
懸念されるため、例えば非ステロイド性抗炎症剤の場合
でもグリチルリチンなどの作用の弱い薬剤や、保湿剤と
してのアロエなどの植物エキスを配合したクリーム、ロ
ーション類の塗布、また冷却した含水タオルによる脱毛
処理部位の冷却などの方法が行われているが、いずれも
速やかな皮膚の改善は得難く、現在のところ脱毛処理後
に生じる皮膚障害に対しては満足のいく処置方法はな
く、自然治癒にまかせているのが現状である。[0008] As for the care of skin disorders that occur after the hair removal treatment, side effects have conventionally been concerned with steroidal anti-inflammatory drugs. For example, even non-steroidal anti-inflammatory drugs have a weak effect such as glycyrrhizin or moisturizing. Cream containing a plant extract such as aloe as an agent, application of lotions, and methods such as cooling of the hair removal treatment site with a cooled water-containing towel have been performed, but it is difficult to quickly improve the skin, At present, there is no satisfactory treatment method for a skin disorder that occurs after the hair removal treatment, and the situation is left to natural healing.
【０００９】このように、脱毛においては脱毛処理によ
って生じる皮膚障害を可及的速やかに元の皮膚状態に戻
す適切な皮膚トリートメント処置を行うことが要求され
ており、また副作用などの不都合がないことが望まれ
る。[0009] As described above, in hair removal, it is required to perform appropriate skin treatment for returning the skin disorder caused by the hair removal treatment to the original skin state as quickly as possible, and there is no inconvenience such as side effects. Is desired.
【００１０】[0010]
【発明が解決しようとする課題】したがってこの発明
は、上記観点からなされたものであり、脱毛処理後に生
じる皮膚障害を安全かつ速やかに改善する脱毛処理後の
皮膚トリートメント外用剤を提供することを課題として
いる。SUMMARY OF THE INVENTION Accordingly, the present invention has been made from the above viewpoint, and an object of the present invention is to provide an external preparation for skin treatment after depilatory treatment which safely and promptly improves skin damage caused after depilatory treatment. And
【００１１】[0011]
【課題を解決するための手段】この発明者らは、上記課
題を解決するために鋭意研究を重ねた結果、特定のω６
系不飽和脂肪酸が脱毛処理後の皮膚障害に対し好結果が
得られることを知り、この発明をなすに至った。Means for Solving the Problems The inventors of the present invention have conducted intensive studies to solve the above-mentioned problems, and as a result, a specific ω6
The inventors of the present invention have found that a systemic unsaturated fatty acid can provide good results for skin disorders after hair removal treatment, and have accomplished the present invention.
【００１２】すなわち、この発明は、γ−リノレン酸、
ジホモ−γ−リノレン酸およびこれらの誘導体から選ば
れる一種または二種以上を含有することを特徴とする脱
毛処理後の皮膚トリートメント外用剤に関する。That is, the present invention provides a γ-linolenic acid,
The present invention relates to an external preparation for skin treatment after depilatory treatment, comprising one or more selected from dihomo-γ-linolenic acid and derivatives thereof.
【００１３】[0013]
【発明の実施の形態】以下に、この発明を詳細に説明す
る。この発明で用いられる有効成分のγ−リノレン酸、
ジホモ−γ−リノレン酸（これらおよびその誘導体を、
以下「γ−リノレン酸等」ということがある）は、ω６
系の必須脂肪酸として知られる内因性の不飽和脂肪酸で
ある。このω６系の脂肪酸は、生体内で下記のような経
路により変換されていくものと考えられている。 この系列の脂肪酸は皮膚を正常に維持していくのに大変
重要な働きをしていると考えられており、また今日で
は、γ−リノレン酸等は単に１系列のプロスタグランジ
ンの前駆物質としての理由だけからではなく、それら独
自の生理作用も注目を集めている。DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in detail. Γ-linolenic acid as an active ingredient used in the present invention,
Dihomo-γ-linolenic acid (these and their derivatives
Hereinafter, it may be referred to as “γ-linolenic acid or the like”)
Endogenous unsaturated fatty acids known as essential fatty acids in the system. It is considered that the ω6-based fatty acid is converted in vivo by the following pathway. Fatty acids of this series are thought to play a very important role in maintaining normal skin, and today, γ-linolenic acid and the like are merely precursors of one series of prostaglandins. Not only for these reasons, but also their unique physiological effects are attracting attention.
【００１４】この発明の脱毛処理後の皮膚トリートメン
ト外用剤が、何故脱毛処理後に生じる皮膚障害を速やか
に改善するのかについては今のところ必ずしも明白では
ないが、脱毛処理により惹起される急性炎症による皮膚
障害に対し、γ−リノレン酸等や１系列のプロスタグラ
ンジン、例えばプロスタグランジンＥ１（ＰＧＥ１）
は、ｃＡＭＰ（ｃｙｃｌｉｃ ＡＭＰ）産生を介して急
性炎症を抑制し、また皮膚の修復にとって大事な真皮の
膠原線維の増生にＰＧＥ１が有効に寄与しているためで
はないかと考えられる。また、γ−リノレン酸等は内因
性の物質であるため皮膚との親和性も良好となり、使用
感や安全性にも好結果が得られる。[0014] It is not always clear why the external preparation for skin treatment after depilatory treatment of the present invention rapidly improves skin disorders caused by depilatory treatment. Against disorders such as γ-linolenic acid and a series of prostaglandins, such as prostaglandin E 1 (PGE 1 )
Via a cAMP (cyclic AMP) production was inhibited acute inflammation, also thought that it is the order PGE 1 is effectively contribute to the hyperplasia of collagen fibers precious dermis for skin repair. In addition, since γ-linolenic acid and the like are endogenous substances, they have good affinity with the skin, and provide good results in use feeling and safety.
【００１５】γ−リノレン酸等は、天然の供給源が限ら
れており、通常、モルティエレラ（Ｍｏｒｔｉｅｒｅｌ
ｌａ）属、ムコール（Ｍｕｃｏｒ）属、リゾプス（Ｒｈ
ｉｚｏｐｕｓ）属等の糸状菌類、あるいは月見草、ボレ
ージ等の植物、さらにはスピルリナ等の藻類等に含まれ
る油脂から得られるが、これらからの抽出物をそのまま
用いてもよく、精製したものを用いてもよい。また、γ
−リノレン酸等は、化学合成によって得ることもでき、
市販されているものを使用してもよい。[0015] Natural sources of γ-linolenic acid and the like are limited, and Mortierella is usually used.
la) genus, Mucor genus, Rhizopus (Rh)
It is obtained from filamentous fungi of the genus Izopus, or plants such as evening primrose and borage, and also from oils and fats contained in algae such as spirulina. Is also good. Also, γ
-Linolenic acid or the like can also be obtained by chemical synthesis,
A commercially available product may be used.
【００１６】また、上記γ−リノレン酸あるいはジホモ
−γ−リノレン酸の誘導体としては、これらと各種アル
コール類との反応により得られるエステル、例えばエチ
ルエステル、グリセロールエステル、リン脂質等、ある
いは無機、有機の塩基とを等モル比で作用して得られる
塩、例えば、ナトリウム塩、カリウム塩等が挙げられ
る。The derivatives of γ-linolenic acid or dihomo-γ-linolenic acid include esters obtained by reacting these with various alcohols, for example, ethyl esters, glycerol esters, phospholipids, etc .; And a salt obtained by acting the compound in an equimolar ratio, for example, a sodium salt, a potassium salt and the like.
【００１７】この発明の脱毛処理後の皮膚トリートメン
ト外用剤は、γ−リノレン酸、ジホモ−γ−リノレン酸
およびこれらの誘導体から選ばれる一種または二種以上
の混合物、あるいは上記糸状菌類や植物等の油脂から得
られる抽出物を、一般に製剤上許容される無害の一種、
あるいは数種のベヒクル、担体、賦形剤、統合剤、防腐
剤、安定剤、香料、着色剤等と共に混和して、液状、乳
液状、クリーム状、ゲル状、ジェリー状、ペースト状等
の外用剤とすることができ、また必要に応じて、パップ
剤、プラスター剤とすることも可能であり、これらは従
来公知の技術を用いて製造することができる。The external preparation for skin treatment after depilatory treatment of the present invention may be one or a mixture of two or more selected from γ-linolenic acid, dihomo-γ-linolenic acid and derivatives thereof, or the above-mentioned filamentous fungi, plants and the like. Extracts obtained from fats and oils, generally harmless kind of pharmaceutically acceptable,
Alternatively, it is mixed with several kinds of vehicles, carriers, excipients, integrating agents, preservatives, stabilizers, fragrances, coloring agents, etc., for external use such as liquid, emulsion, cream, gel, jelly, paste, etc. And, if necessary, cataplasms and plasters, which can be produced using conventionally known techniques.
【００１８】このように、この発明の皮膚トリートメン
ト外用剤の剤型は特に限定されるものではないが、皮膚
からの吸収や製造の簡便さ、また必要に応じて塗布後マ
ッサージを施すこと等を考慮した場合、油液（オイル）
状とするのが好ましい。このような製剤例として、後記
実施例においてγ−リノレン酸含有油脂とビタミンＥと
の組合わせ例を挙げたが、この油液製剤はベトツキ感が
なく、また安全性や使用感にも優れたものである。As described above, the dosage form of the external preparation for skin treatment of the present invention is not particularly limited. However, it is important that absorption from the skin and simplicity of production and that, if necessary, massaging after application are performed. Considering the oil liquid (oil)
It is preferred to be in the form. As an example of such a formulation, a combination example of γ-linolenic acid-containing fats and oils and vitamin E was given in the examples described later, but this oil liquid formulation has no stickiness and is excellent in safety and usability. Things.
【００１９】この発明の外用剤には、例えばゴマ油、ダ
イズ油、オリーブ油等の油脂類、α−リノレン酸、エイ
コサペンタエン酸、ドコサヘキサエン酸、ミリストオレ
イン酸、パルミトオレイン酸、オレイン酸、エルシン
酸、ラウリン酸、ミリスチン酸等の脂肪酸類；ビタミン
Ｅ及びその誘導体、γ−オリザノール等の抗酸化剤；グ
リセリン、ポリエチレングリコール、プロピレングリコ
ール等の保湿剤；サリチル酸メチル等の局所消炎鎮痒
剤；水などを配合してもよく、これらは一種または二種
以上が用いられる。これらの中でもビタミンＥ及びその
誘導体が好適に用いられる。ビタミンＥは、上記理由に
加えその抗酸化作用によってγ−リノレン酸等の酸化を
防止するとともに正常な膜機能の維持に寄与していると
考えられているからである。The external preparation of the present invention includes oils and fats such as sesame oil, soybean oil and olive oil, α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, myristooleic acid, palmitooleic acid, oleic acid and erucic acid. Fatty acids such as glycerol, lauric acid and myristic acid; antioxidants such as vitamin E and its derivatives, γ-oryzanol; humectants such as glycerin, polyethylene glycol and propylene glycol; local anti-inflammatory and antipruritic agents such as methyl salicylate; One or two or more of these may be used. Among them, vitamin E and its derivatives are preferably used. Vitamin E is considered to contribute to the maintenance of a normal membrane function while preventing the oxidation of γ-linolenic acid and the like by its antioxidant action in addition to the above-mentioned reason.
【００２０】脱毛処理後の皮膚トリートメント外用剤中
のγ−リノレン酸の含有量（ジホモ−γ−リノレン酸お
よび各誘導体については、γ−リノレン酸量に換算され
る）としては特に制限はないが、少なくなり過ぎると皮
膚障害の治療効果が充分に得られなくなり、また多くな
り過ぎても経済的に高価となるなどの不都合が生じるの
で、通常は１〜３０重量％の範囲内で用いられる。The content of γ-linolenic acid in the external preparation for skin treatment after depilatory treatment is not particularly limited (the content of dihomo-γ-linolenic acid and each derivative is converted to the amount of γ-linolenic acid). If the amount is too small, the effect of treating the skin disorder will not be sufficiently obtained, and if the amount is too large, it will be economically expensive. Therefore, it is usually used in the range of 1 to 30% by weight.
【００２１】このようにして得られるこの発明の皮膚ト
リートメント外用剤の使用方法としては、脱毛処理直後
の処理部位に塗布、軽く展延するようにすればよい。ま
た、脱毛処理前に予め処理部位に塗布しておくようにし
てもよい。The method for using the external preparation for skin treatment of the present invention thus obtained may be applied to the treatment site immediately after the hair removal treatment and spread lightly. Moreover, you may make it apply | coat to a process part beforehand before a hair removal process.
【００２２】[0022]
【実施例】以下に、この発明の脱毛処理後の皮膚トリー
トメント外用剤を用いた実施例を説明するが、この発明
の範囲はこれらの実施例に限定されるものではない。EXAMPLES Examples using the external preparation for skin treatment after depilatory treatment of the present invention will be described below, but the scope of the present invention is not limited to these examples.
【００２３】〈外用剤の製法〉モルティエレラ（Ｍｏｒ
ｔｉｅｒｅｌｌａ）属菌体より抽出したγ−リノレン酸
含有油脂（出光マテリアル（株）製商品名：ＧＬＡＲＯ
０８、γ−リノレン酸を約８重量％含有）１重量部と、
ビタミンＥ（エーザイ（株）製商品名：イーミックス−
８０）１重量部とを、混合・撹拌し、この発明に係る脱
毛処理後の皮膚トリートメント外用剤を製造した。<Production method of external preparation> Mortierella (Mor
gamma-linolenic acid-containing oils and fats extracted from cells of the genus tierella) (trade name: GLARO, manufactured by Idemitsu Materials Co., Ltd.)
08, containing about 8% by weight of γ-linolenic acid) 1 part by weight;
Vitamin E (trade name: EMIX manufactured by Eisai Co., Ltd.)
80) 1 part by weight was mixed and stirred to produce an external preparation for skin treatment after depilatory treatment according to the present invention.
【００２４】〈使用試験〉この発明の皮膚トリートメン
ト外用剤の効果を明らかにするため、上記製法により得
られたこの発明の外用剤を用いて電気脱毛法での使用試
験を行った。<Usage Test> In order to clarify the effect of the external preparation for skin treatment of the present invention, a use test in the electric hair removal method was performed using the external preparation of the present invention obtained by the above-mentioned production method.
【００２５】（１）方法 わき毛の電気脱毛処理を受ける被験者１６名（１８〜４
２歳の女性）をそれぞれ無作為に抽出し、Ａ群（８
名）、Ｂ群（８名）に分け、Ａ群にはこの発明の皮膚ト
リートメント外用剤を脱毛処理直後に塗布し、またＢ群
は脱毛処理後無処置とし、自然治癒に任せた。次に、脱
毛処理直後と脱毛処理１日後との脱毛処理部位の皮膚状
態を目視にて比較し、以下の評価により改善率を求め
た。結果を表１に示す。(1) Method 16 subjects (18-4
A 2-year-old woman) was randomly selected, and group A (8
) And Group B (8 persons). The external preparation for skin treatment of the present invention was applied to Group A immediately after the hair removal treatment, and Group B was left untreated after the hair removal treatment and left to natural healing. Next, the skin condition of the depilation treatment site immediately after the depilation treatment and one day after the depilation treatment was visually compared, and the improvement rate was determined by the following evaluation. Table 1 shows the results.
【００２６】（２）評価 ＋＋＋：脱毛処理による皮膚障害が殆ど回復 ＋＋ ：脱毛処理による皮膚障害がかなり回復 ＋ ：脱毛処理による皮膚障害がやや回復 − ：脱毛処理による皮膚障害に変化なし 悪 化：脱毛処理による皮膚障害が悪化(2) Evaluation +++: Almost all skin damage due to hair removal treatment is recovered. Hair damage worsens skin damage
【００２７】 改善率は＋＋または＋＋＋を示した割合をいい、肌を露
出しても気にならない程度まで回復したことを示す。上
記結果から、この発明に係る脱毛処理後の皮膚トリート
メント外用剤で処置したＡ群は、無処置のＢ群に比し、
脱毛処理後の皮膚障害が早く改善されていることが判
る。また、Ａ群の＋＋＋評価の５名の被験者のうち３名
は処理後３時間以内に改善効果が得られた。これに対し
て、Ｂ群の一評価の７名の被験者が十評価になったの
は、５名が２日後、２名は５日後であった。なお、Ａ群
８名全員にこの発明の皮膚トリートメント外用剤使用に
よる副作用は全く見られなかった。[0027] The improvement rate refers to a ratio indicating ++ or +++, and indicates that the skin has recovered to a level that is not bothersome even when the skin is exposed. From the above results, the group A treated with the external preparation for skin treatment after the hair removal treatment according to the present invention, compared to the untreated group B,
It can be seen that the skin disorder after the hair removal treatment was quickly improved. In addition, three of the five subjects in the +++ evaluation of the group A had an improvement effect within 3 hours after the treatment. On the other hand, seven subjects in one evaluation of group B received ten evaluations, five after two days and two after five days. In addition, no side effect was observed at all in the group A 8 patients due to the use of the external preparation for skin treatment of the present invention.
【００２８】また、Ａ群８名の被験者を対象としたこの
発明の皮膚トリートメント外用剤の使用感について、
使用後の肌の状態、使用時のベタツキ感について調査
した結果を表２にまとめた。The feeling of use of the external preparation for skin treatment of the present invention for 8 subjects in Group A is as follows.
Table 2 summarizes the results of an investigation on the skin condition after use and the stickiness during use.
【００２９】 上記結果から明らかなように、この発明に係る脱毛処理
後の皮膚トリートメント外用剤は、脱毛処理後の皮膚障
害を速やかに改善し、安全性にも問題がなく、また使用
感にも優れていることが判る。[0029] As is clear from the above results, the skin treatment external preparation after depilatory treatment according to the present invention rapidly improves skin disorders after depilatory treatment, has no problem in safety, and is excellent in usability. You can see that.
【００３０】[0030]
【発明の効果】この発明の脱毛処理後の皮膚トリートメ
ント外用剤は、脱毛処理後に生じる皮膚障害に対し、塗
布後速やかに皮膚改善効果が得られており、また安全性
や使用感にも優れている。EFFECT OF THE INVENTION The external preparation for skin treatment after depilatory treatment of the present invention has an effect of improving the skin immediately after application against skin disorders occurring after the depilatory treatment, and also has excellent safety and usability. I have.
───────────────────────────────────────────────────── フロントページの続き (72)発明者 須賀田 直子 東京都港区芝５丁目６番１号 ──────────────────────────────────────────────────の Continuation of the front page (72) Inventor Naoko Sugada 5-6-1 Shiba, Minato-ku, Tokyo
Claims (1)
およびこれらの誘導体から選ばれる一種または二種以上
を含有することを特徴とする脱毛処理後の皮膚トリート
メント外用剤。1. An external preparation for skin treatment after depilatory treatment, comprising one or more selected from γ-linolenic acid, dihomo-γ-linolenic acid and derivatives thereof.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6371197A JPH10218731A (en) | 1997-02-10 | 1997-02-10 | Preparation for external use for skin treatment after depilation treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6371197A JPH10218731A (en) | 1997-02-10 | 1997-02-10 | Preparation for external use for skin treatment after depilation treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH10218731A true JPH10218731A (en) | 1998-08-18 |
Family
ID=13237246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6371197A Pending JPH10218731A (en) | 1997-02-10 | 1997-02-10 | Preparation for external use for skin treatment after depilation treatment |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH10218731A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012153832A1 (en) * | 2011-05-12 | 2012-11-15 | 日本水産株式会社 | Composition for external skin use for inflammatory diseases |
| US9216304B2 (en) | 2010-03-26 | 2015-12-22 | The Gillette Company | Method of depilation and depilatory kit |
| US9820484B2 (en) | 2013-12-04 | 2017-11-21 | Nippon Suisan Kaisha, Ltd. | Dihomo-γ-linolenic acid-containing microbial oil and dihomo-γ-linolenic acid-containing microbial biomass |
-
1997
- 1997-02-10 JP JP6371197A patent/JPH10218731A/en active Pending
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9216304B2 (en) | 2010-03-26 | 2015-12-22 | The Gillette Company | Method of depilation and depilatory kit |
| JP2018076367A (en) * | 2011-05-12 | 2018-05-17 | 日本水産株式会社 | Skin external composition for inflammatory disease |
| JPWO2012153832A1 (en) * | 2011-05-12 | 2014-07-31 | 日本水産株式会社 | Skin composition for inflammatory diseases |
| US9220702B2 (en) | 2011-05-12 | 2015-12-29 | Nippon Suisan Kaisha, Ltd. | Composition for external use on skin for inflammatory diseases |
| JP2016172753A (en) * | 2011-05-12 | 2016-09-29 | 日本水産株式会社 | Composition for external use on skin for inflammatory disease |
| WO2012153832A1 (en) * | 2011-05-12 | 2012-11-15 | 日本水産株式会社 | Composition for external skin use for inflammatory diseases |
| JP2019178165A (en) * | 2011-05-12 | 2019-10-17 | 日本水産株式会社 | Composition for external use on skin for inflammatory disease |
| US10525028B2 (en) | 2011-05-12 | 2020-01-07 | Nippon Suisan Kaisha, Ltd. | Composition for external use on skin for inflammatory diseases |
| US11103476B2 (en) | 2011-05-12 | 2021-08-31 | Nippon Suisan Kaisha, Ltd. | Composition for external use on skin for inflammatory diseases |
| US11819486B2 (en) | 2011-05-12 | 2023-11-21 | Nissui Corporation | Composition for external use on skin for inflammatory diseases |
| US9820484B2 (en) | 2013-12-04 | 2017-11-21 | Nippon Suisan Kaisha, Ltd. | Dihomo-γ-linolenic acid-containing microbial oil and dihomo-γ-linolenic acid-containing microbial biomass |
| US10750741B2 (en) | 2013-12-04 | 2020-08-25 | Nippon Suisan Kaisha, Ltd. | Dihomo-γ-linolenic acid-containing microbial oil and dihomo-γ-linolenic acid-containing microbial biomass |
| US11330817B2 (en) | 2013-12-04 | 2022-05-17 | Nippon Suisan Kaisha, Ltd. | Microbial oil, production method for microbial oil, concentrated microbial oil, and production method for concentrated microbial oil |
| US11856952B2 (en) | 2013-12-04 | 2024-01-02 | Nippon Suisan Kaisha, Ltd. | Microbial oil, production method for microbial oil, concentrated microbial oil, and production method for concentrated microbial oil |
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