JPH10118193A - Guide wire for catheter - Google Patents
Guide wire for catheterInfo
- Publication number
- JPH10118193A JPH10118193A JP8277853A JP27785396A JPH10118193A JP H10118193 A JPH10118193 A JP H10118193A JP 8277853 A JP8277853 A JP 8277853A JP 27785396 A JP27785396 A JP 27785396A JP H10118193 A JPH10118193 A JP H10118193A
- Authority
- JP
- Japan
- Prior art keywords
- guide wire
- catheter
- shape memory
- tube
- tip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、医療用器具である
カテーテル用ガイドワイヤーに関するものである。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a guide wire for a catheter which is a medical instrument.
【０００２】[0002]
【従来の技術】一般に、カテーテル用ガイドワイヤー
は、血管部位から穿刺したセルディンガー針により血管
内に導入された後、セルディンガー針をカテーテル用ガ
イドワイヤーから取り外し、その後カテーテル用ガイド
ワイヤーの後端にカテーテルを取り付けて、生体の脈
管、特に血管内の目的部位までカテーテルに先行してカ
テーテルを案内するために用いられる医科用器具であ
る。特に最近では、細い血管部にも挿入することがある
ために、これまで以上に、より細いカテーテル用ガイド
ワイヤーが望まれている。2. Description of the Related Art Generally, a catheter guide wire is introduced into a blood vessel by a Seldinger needle punctured from a vascular site, and then the Seldinger needle is removed from the catheter guide wire. It is a medical device used to attach a catheter and guide the catheter prior to the catheter to a target site in a vessel of a living body, in particular, a blood vessel. Particularly in recent years, since a catheter may be inserted into a thin blood vessel, a catheter guide wire which is thinner than ever is desired.
【０００３】このため、カテーテル用ガイドワイヤーは
複雑な形状を呈する先端部と、基質部とを有し、生体温
度（約３７℃）において、血管導入・移動時に求められ
る対キンク性・突きだし性およびトルク伝達性に優れな
ければならない。しかし、単なる弾性特性を有する非形
状記憶合金素材を用いたカテーテル用ガイドワイヤーで
は、複雑な血管内への導入時に塑性変形しやすいため、
医者や患者の双方にとって生理的苦痛等を与えてしまう
問題があった。[0003] For this reason, a guide wire for a catheter has a tip portion having a complicated shape and a substrate portion, and at the biological temperature (about 37 ° C), it has the anti-kink property and the sticking property required at the time of blood vessel introduction and movement. It must have excellent torque transmission. However, a guide wire for a catheter using a non-shape memory alloy material having a mere elastic property is likely to be plastically deformed when introduced into a complicated blood vessel,
There has been a problem that both the doctor and the patient suffer from physiological pain.
【０００４】特に、カテーテル用ガイドワイヤーの先端
部は血管を傷つけないために柔らかく、且つ導入をスム
ーズに行うために対キンク性が基質部以上に求められ
る。この為に先端部はヘリカルコイル状とされている。[0004] In particular, the distal end portion of the catheter guide wire is required to be soft so as not to damage the blood vessel and to have a kink resistance higher than that of the substrate portion in order to smoothly introduce the blood vessel. For this reason, the tip is formed in a helical coil shape.
【０００５】そこで、従来ではＴｉＮｉ系合金を通常３
０％〜４０％冷間加工を施した後、４００℃〜５００℃
の熱処理を行うことにより、焼鈍して改良した焼鈍材を
生成し、これにより体内（約３７℃）において、一定応
力によっても伸び変形等の増加を示し（以下超弾性特性
という）、可逆的なエネルギーの吸収・放出及び可逆的
な形状の変形・回復を行えるカテーテル用ガイドワイヤ
ーが得られていた。この場合の先端部は血管を傷つけな
いためにテーパリングで柔らかくしている（例えば、特
開昭６３−１７１５７０号公報参照）。Therefore, conventionally, a TiNi-based alloy is usually
0% to 40% after cold working, 400 ° C to 500 ° C
By performing the heat treatment described above, an improved annealed material is produced by annealing, whereby in the body (approximately 37 ° C.), an increase in elongation deformation and the like is exhibited even under a constant stress (hereinafter, referred to as superelastic property). A guide wire for a catheter capable of absorbing and releasing energy and reversing and recovering a reversible shape has been obtained. In this case, the distal end portion is softened by tapering so as not to damage the blood vessel (see, for example, JP-A-63-171570).
【０００６】しかしながら、特に最近かなり細い血管へ
の案内に際し、基本的にカテーテル用ガイドワイヤーの
太さに限界があり、従来のＴｉＮｉ系合金の焼鈍材を用
いたカテーテル用ガイドワイヤーでは、ステンレス線を
用いたものと比較すると、その剛性が約１／２程度と低
く、筋肉の収縮等の応力に抗してカテーテルを人体内の
所望の部位（特に細い部位）に導くことが困難である。
すなわち、手元での操作、例えばひねりを伝えるトルク
伝達性や押し込みを伝える剛性（プッシャビリティー）
が不十分であった。[0006] However, particularly when guiding to a very thin blood vessel recently, there is basically a limit in the thickness of the guide wire for a catheter, and a conventional guide wire for a catheter using an annealed material of a TiNi-based alloy requires a stainless wire. Compared to those used, the rigidity is as low as about 1/2, and it is difficult to guide the catheter to a desired site (particularly a thin site) in the human body against stress such as muscle contraction.
In other words, operation at hand, for example, torque transmission to transmit a twist and rigidity to transmit a push (pushability)
Was inadequate.
【０００７】そこで、更にその欠点を改善すべく、少な
くとも体温（３７℃）下で先端部にしなやかさを維持さ
せる一方、基質部には剛性を維持させたカテーテル用ガ
イドワイヤーが提案されている。それは、超弾性合金か
らなるカテーテル用ガイドワイヤーにおいて、血管導入
先端部を除く当該表面の少なくとも一部が、無機皮膜
（Ｎｉ皮膜など）で覆われているもので一種のクラッド
を形成しているというものである（例えば、特開平２−
２８９２６６号公報参照）。Therefore, in order to further improve the drawback, a guide wire for a catheter has been proposed in which at the body temperature (37 ° C.) the flexibility at the distal end is maintained while the rigidity is maintained at the matrix. That is, in a guide wire for a catheter made of a superelastic alloy, at least a part of the surface except for a blood vessel introduction tip is covered with an inorganic film (such as a Ni film) to form a kind of clad. (See, for example,
289266).
【０００８】[0008]
【発明が解決しようとする課題】しかしながら、特開平
２−２８９２６６号公報記載のカテーテル用ガイドワイ
ヤーは、超弾性特性の劣化傾向が著しく、実際に血管へ
の挿入時において押し込みを伝える剛性そのものは十分
にあっても、しなやかさがないために、目的の部位に案
内できない等の問題があった。しかし特願平５−２９４
４３７号に見られるように上記問題点を解決するような
提案がなされている。However, the guide wire for a catheter disclosed in Japanese Patent Application Laid-Open No. 2-289266 has a remarkable tendency to deteriorate the superelastic property, and the rigidity for transmitting the push when actually inserted into a blood vessel is sufficient. However, there is a problem that the user cannot be guided to a target part because of lack of flexibility. However, Japanese Patent Application Hei 5-294
As suggested in Japanese Patent No. 437, a proposal for solving the above problem has been made.
【０００９】つまり、この特願平５−２９４４３７号に
開示される発明は、少なくとも一部が形状記憶合金製部
材で構成されたカテーテル用ガイドワイヤーであって、
その一部或いは全部が形状記憶合金製チューブであっ
て、その形状記憶合金製チューブの一部或いは全部に芯
材として少なくとも一種もしくは数種の非形状記憶合金
線が挿入され、前記カテーテル用ガイドワイヤーを構成
する芯材が先端部、基質部とに分離され、先端部がテー
パリングされているか、或いはヘリカル状のバネで構成
され、且つその芯材の先端部が非形状記憶合金線からな
るバネで構成され、形状記憶合金が少なくとも生体温度
で超弾性を示すという特徴を有するものである。In other words, the invention disclosed in Japanese Patent Application No. 5-294337 is a guide wire for a catheter at least partially constituted by a member made of a shape memory alloy.
Part or all of the tube is a shape memory alloy tube, and at least one or several types of non-shape memory alloy wires are inserted as a core material into a part or the whole of the shape memory alloy tube, and the catheter guide wire is used. The core material is separated into a tip portion and a substrate portion, and the tip portion is tapered or formed of a helical spring, and the tip portion of the core material is formed of a non-shape memory alloy wire. And the feature that the shape memory alloy exhibits superelasticity at least at a biological temperature.
【００１０】しかしいずれの場合でも、先端部の構成は
複雑となるためにコスト上問題を残している。そこで本
発明の課題は、少なくとも先端部にしなやかさを維持さ
せる一方、基質部には剛性を維持させたカテーテルガイ
ドワイヤーであって、且つ最先端部を柔らかくしたガイ
ドワイヤーを安価に提供することにある。However, in any case, the structure of the tip portion is complicated, so that there is a problem in cost. Therefore, an object of the present invention is to provide an inexpensive guide wire having a catheter guide wire in which at least the distal end portion is kept supple, while the substrate portion is kept rigid, and the distal end portion is softened. is there.
【００１１】[0011]
【課題を解決するための手段】本発明によれば、最先端
部が形状記憶樹脂で構成されていることを特徴とするカ
テーテル用ガイドワイヤーが得られる。According to the present invention, there is provided a guide wire for a catheter, wherein the distal end portion is made of a shape memory resin.
【００１２】また、本発明によれば、少なくとも一部が
形状記憶合金製であるチューブと、一種又は数種の非形
状記憶合金線から成る芯材とを含み、前記芯材は、基質
部、該基質部に連設された先端部を有し、前記基質部
は、前記チューブに挿入されており、前記先端部は、テ
ーパリングされており、前記先端部の先端に、形状記憶
樹脂で構成されたキャップが取り付けられていることを
特徴とするカテーテル用ガイドワイヤーが得られる。Further, according to the present invention, there is provided a tube at least partially made of a shape memory alloy, and a core material made of one or several kinds of non-shape memory alloy wires, wherein the core material has a substrate portion, A tip portion connected to the substrate portion, wherein the substrate portion is inserted into the tube, the tip portion is tapered, and a tip end of the tip portion is formed of a shape memory resin. A guide wire for a catheter, characterized in that the fitted cap is attached.
【００１３】[0013]
【発明の実施の形態】以下、本発明の実施の形態につい
て説明する。Embodiments of the present invention will be described below.
【００１４】第１の実施形態：表１に現在血管造影用に
使用されている形状記憶合金製のカテーテル用ガイドワ
イヤーと、本発明の第１の実施形態に係る最先端部を形
状記憶樹脂製としたカテーテル用ガイドワイヤーにおい
て、支点間距離を２５ｍｍにして押し込み量が５ｍｍで
の三点曲げ試験（形状記憶合金の曲げ荷重を１００とし
た場合）の結果を示す。First Embodiment: Table 1 shows a guide wire for a catheter made of a shape memory alloy currently used for angiography, and a tip portion made of a shape memory resin according to the first embodiment of the present invention. 3 shows the results of a three-point bending test (when the bending load of the shape memory alloy is 100) when the distance between fulcrums is 25 mm and the indentation amount is 5 mm in the guide wire for a catheter.
【００１５】テストに使用した形状記憶合金はまず、原
子％でＮｉ５１ａｔ％、残部がＴｉからなるＴｉ−５１
ａｔ％Ｎｉ系合金を高周波真空溶解によって得た。尚、
この合金は、アーク溶解法、電子ビーム法、或いは粉末
冶金法によっても作製できる。The shape memory alloy used in the test was first made of Ti-51 consisting of 51 at% of Ni in atomic% and the balance being Ti.
An at% Ni-based alloy was obtained by high-frequency vacuum melting. still,
This alloy can also be produced by an arc melting method, an electron beam method, or a powder metallurgy method.
【００１６】次に、得られたＴｉＮｉ系合金を９００〜
１０００℃で溶体化処理後、約９００℃で熱間鍛造、熱
間圧延等を施し、丸棒にした後、冷間加工によりφ０．
２ｍｍのワイヤに加工した。得られたφ０．２ｍｍのワ
イヤの全体に渡って、５００℃で１０分間の熱処理を張
力下で行い、直線性を与えるとともに、超弾性特性を付
与した。Next, the obtained TiNi-based alloy was
After solution treatment at 1000 ° C., hot forging, hot rolling, etc. are performed at about 900 ° C. to form round bars, and φ0.
It was processed into a 2 mm wire. A heat treatment at 500 ° C. for 10 minutes was performed under tension over the whole of the obtained φ0.2 mm wire to give linearity and superelastic properties.
【００１７】一方、本実施形態のカテーテル用ガイドワ
イヤーに用いられた形状記憶樹脂は、ポリノルボルネン
製で形状回復温度は５℃で、寸法はφ０．２ｍｍのもの
を使用した。表１から明らかなように、形状記憶樹脂は
形状記憶合金の１／１００の変形応力であり非常に柔ら
かく血管の損傷が少ないことが十分予想できる。On the other hand, the shape memory resin used for the catheter guide wire of the present embodiment was made of polynorbornene and had a shape recovery temperature of 5 ° C. and a size of φ0.2 mm. As is clear from Table 1, it can be sufficiently expected that the shape memory resin has a deformation stress of 1/100 of that of the shape memory alloy, and is very soft and causes little damage to blood vessels.
【００１８】[0018]
【表１】 [Table 1]
【００１９】第２の実施形態：本実施形態のカテーテル
用ガイドワイヤーは、体温（３７℃）下で、最先端部が
柔らかく、先端部にしなやかさを維持させつつ、基質部
に剛性を持たせたことを特徴とするものであり、以下、
このカテーテル用ガイドワイヤーについて説明する。Second Embodiment: The guide wire for a catheter according to the present embodiment has a rigid distal end portion at body temperature (37 ° C.) and a rigidity at the distal end portion while maintaining rigidity in the substrate portion. It is characterized by the following,
This catheter guide wire will be described.
【００２０】先ず、原子％でＮｉ５１ａｔ％、残部がＴ
ｉからなるＴｉ−５１ａｔ％Ｎｉ系合金を高周波真空溶
解によって得た。尚、この合金は、アーク溶解法、電子
ビーム法、或いは粉末冶金法によっても作製できる。First, Ni is 51 at% in atomic%, and the balance is T
A Ti-51 at% Ni-based alloy consisting of i was obtained by high-frequency vacuum melting. In addition, this alloy can also be manufactured by an arc melting method, an electron beam method, or a powder metallurgy method.
【００２１】次に、得られたＴｉＮｉ系合金を９００〜
１０００℃で溶体化処理後、約９００℃で熱間鍛造、熱
間圧延等を施し、丸棒にした後、穴開けを行いその後、
冷間加工により外径０．２ｍｍで厚み０．０２５ｍｍの
サイズのチューブに加工した。得られた外径０．２ｍｍ
のサイズのチューブの全体に渡って、５００℃で１０分
間の熱処理を張力下で行い、直線性を与えるとともに、
超弾性特性を付与した。Next, the obtained TiNi-based alloy was
After solution heat treatment at 1000 ° C, hot forging, hot rolling and the like are performed at about 900 ° C, and after round bars are formed, holes are drilled.
The tube was formed into a tube having an outer diameter of 0.2 mm and a thickness of 0.025 mm by cold working. Obtained outer diameter 0.2mm
Heat treatment at 500 ° C. for 10 minutes under tension over the entire size of the tube to give linearity,
Superelastic properties were imparted.
【００２２】その後、チューブの芯材として、φ０．１
３ｍｍのステンレス線を先のＴｉＮｉ合金製チューブに
挿入し、更にこの芯材の先端部にキャップを取り付け
た。以下、この点を図面を用いて更に詳しく説明する。Then, as a core material of the tube, φ0.1
A 3 mm stainless steel wire was inserted into the TiNi alloy tube, and a cap was attached to the tip of the core material. Hereinafter, this point will be described in more detail with reference to the drawings.
【００２３】図１は第２の実施形態に係るカテーテル用
ガイドワイヤーの断面を示す。このカテーテル用ガイド
ワイヤー１は、上述のＴｉＮｉ合金製チューブ２と、芯
材３と、キャップ４とから成る。芯材３は、１本のステ
ンレス線（例えば、ＴｉＮｉ超弾性線でも良い）から成
り、基質部３０と、この基質部３０に一体に連設された
先端部３１（約１００ｍｍ程度）とを有している。基質
部３０は、チューブ２内に挿入されてる。先端部３１
は、テーパリングしてある。キャップ４は、形状記憶合
金樹脂のチューブで構成されており、芯材３の先端部３
１の先端に取り付けられている。このキャップ４は、全
体として見れば、カテーテル用ガイドワイヤー１の最先
端部と成っている。ここでキャップ４の素材として用い
られている形状記憶樹脂は、ポリノルボルネン製で形状
回復温度は５℃であり、また、キャップ４として用いら
れている形状記憶樹脂製のチューブは、寸法が、外径
０．１８ｍｍ、内径０．１ｍｍのものを使用した。本実
施形態では、チューブ２と、芯材３（基質部３０、及び
先端部３１）と、キャップ４との組み合わせは、図１に
示すように、チューブ２に、基質部３０とテーパリング
してある先端部３１とを有する芯材３を通し、チューブ
２の後端と、基質部３０の後端とを接合してこれらを一
体化したものとした。更に、この芯材３の先端部３１の
先端に形状記憶樹脂製チューブであるキャップ４を室温
（２２℃）で接着した。このように、先端部３１はステ
ンレス線のテーパリングしたものであって、押し込み性
を維持しつつ、細いために柔軟性がある。またカテーテ
ル用ガイドワイヤー１の最先端部であるキャップ４は、
ステンレス線よりも柔らかい形状記憶樹脂製チューブか
ら成り、従って、血管内壁を損傷することがない。更に
基質部３０については、その外側に超弾性材のチューブ
２が存在することで、しなやかさと剛性を併せ持つとい
う画期的なものが得られ、これまで挿入できなかった細
い血管へも血管内壁を損傷することなく案内することが
できる。FIG. 1 shows a cross section of a catheter guide wire according to a second embodiment. The catheter guide wire 1 includes the above-described tube 2 made of TiNi alloy, a core material 3, and a cap 4. The core member 3 is made of one stainless wire (for example, a TiNi superelastic wire), and has a substrate portion 30 and a tip portion 31 (about 100 mm) integrally provided with the substrate portion 30. doing. The substrate part 30 is inserted into the tube 2. Tip 31
Is tapered. The cap 4 is made of a tube made of a shape memory alloy resin,
1 is attached to the tip. The cap 4 is the leading end of the catheter guide wire 1 as a whole. Here, the shape memory resin used as the material of the cap 4 is made of polynorbornene and has a shape recovery temperature of 5 ° C. Further, the tube made of the shape memory resin used as the cap 4 has an outside dimension. One having a diameter of 0.18 mm and an inner diameter of 0.1 mm was used. In the present embodiment, the combination of the tube 2, the core material 3 (the substrate portion 30 and the distal end portion 31), and the cap 4 is formed by tapering the tube 2 with the substrate portion 30, as shown in FIG. The core material 3 having a certain front end portion 31 was passed through, and the rear end of the tube 2 and the rear end of the substrate portion 30 were joined to be integrated. Further, a cap 4 which is a tube made of a shape memory resin was adhered to the tip of the tip 31 of the core material 3 at room temperature (22 ° C.). As described above, the distal end portion 31 is formed by tapering the stainless wire, and is thin and flexible while maintaining the indentability. In addition, the cap 4, which is the tip of the guide wire 1 for a catheter,
It is made of a shape memory resin tube that is softer than stainless steel wire, and therefore does not damage the blood vessel inner wall. Further, as for the substrate part 30, the presence of the superelastic tube 2 on the outer side thereof provides an epoch-making material having both flexibility and rigidity. Guidance can be provided without damage.
【００２４】このことは、表２に本実施形態のカテーテ
ル用ガイドワイヤーの基質部、カテーテル用ガイドワイ
ヤーの先端部（テーパリングされた途中の部分であって
φ０．１ｍｍ）、及びカテーテル用ガイドワイヤーの最
先端部（形状記憶樹脂製チューブから成るキャップ）の
３７℃（生体温度）での三点曲げ試験結果を示すが、カ
テーテル用ガイドワイヤー先端部の曲げ荷重は、カテー
テル用カイドワイヤー基質部の約１／３の値となってお
り、更にカテーテル用ガイドワイヤーの最先端部（形状
記憶樹脂製チューブから成るキャップ）は約１／１０の
値を示すことからも明らかである。This is shown in Table 2 in Table 2 in which the base portion of the catheter guide wire according to the present embodiment, the distal end portion of the catheter guide wire (a portion in the middle of the tapered portion, which is φ0.1 mm), and the catheter guide wire The results of a three-point bending test at 37 ° C. (biological temperature) of the foremost part (cap made of a tube made of shape memory resin) are shown. The bending load at the tip of the guide wire for catheter is The value is about 1/3, and it is clear from the fact that the distal end of the catheter guide wire (cap made of a shape memory resin tube) shows a value of about 1/10.
【００２５】[0025]
【表２】 [Table 2]
【００２６】[0026]
【発明の効果】以上の説明からわかるように、本発明に
よれば、少なくとも体温（３７℃）下で先端部にしなや
かさを維持させつつ基質部に剛性を持たせ、更に最先端
部が柔らかく血管内壁を損傷しないカテーテル用ガイド
ワイヤーを得ることができる。As can be seen from the above description, according to the present invention, the substrate is made rigid while maintaining the flexibility at the distal end at least at body temperature (37 ° C.), and the tip is made softer. A catheter guide wire that does not damage the inner wall of the blood vessel can be obtained.
【００２７】しかも、本発明では、先端部をテーパリン
グし、更に最先端部を形状記憶樹脂で構成したので、本
発明によれば、優れた特性を有するカテーテル用ガイド
ワイヤーを安価に得ることができる。Moreover, in the present invention, the distal end is tapered, and the most distal end is made of a shape memory resin. Therefore, according to the present invention, a catheter guide wire having excellent characteristics can be obtained at low cost. it can.
【図１】本発明の第２の実施形態に係るカテーテル用ガ
イドワイヤーの断面図である。FIG. 1 is a cross-sectional view of a catheter guide wire according to a second embodiment of the present invention.
１ カテーテル用ガイドワイヤー ２ チューブ ３ 芯材 ４ キャップ ３０ 基質部 ３１ 先端部 DESCRIPTION OF SYMBOLS 1 Guide wire for catheter 2 Tube 3 Core material 4 Cap 30 Substrate part 31 Tip part
Claims (2)
ることを特徴とするカテーテル用ガイドワイヤー。1. A guide wire for a catheter, wherein a distal end portion is made of a shape memory resin.
チューブと、一種又は数種の非形状記憶合金線から成る
芯材とを含み、前記芯材は、基質部、該基質部に連設さ
れた先端部を有し、前記基質部は、前記チューブに挿入
されており、前記先端部は、テーパリングされており、
前記先端部の先端に、形状記憶樹脂で構成されたキャッ
プが取り付けられていることを特徴とするカテーテル用
ガイドワイヤー。2. A tube comprising at least a portion made of a shape memory alloy, and a core made of one or several kinds of non-shape memory alloy wires, wherein the core is provided in a matrix portion and connected to the matrix portion. A tip portion, the substrate portion is inserted into the tube, the tip portion is tapered,
A guide wire for a catheter, wherein a cap made of a shape memory resin is attached to a tip of the tip.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8277853A JPH10118193A (en) | 1996-10-21 | 1996-10-21 | Guide wire for catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8277853A JPH10118193A (en) | 1996-10-21 | 1996-10-21 | Guide wire for catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH10118193A true JPH10118193A (en) | 1998-05-12 |
Family
ID=17589196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8277853A Withdrawn JPH10118193A (en) | 1996-10-21 | 1996-10-21 | Guide wire for catheter |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH10118193A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11226131A (en) * | 1997-11-21 | 1999-08-24 | Sarcos Inc | Improved hybrid catheter guiding wire device |
| WO2014162393A1 (en) * | 2013-04-01 | 2014-10-09 | テルモ株式会社 | Guide wire |
| US8870790B2 (en) | 2002-07-25 | 2014-10-28 | Boston Scientific Scimed, Inc. | Medical device for navigation through anatomy and method of making same |
| US9023011B2 (en) | 2003-03-27 | 2015-05-05 | Boston Scientific Scimed, Inc. | Medical device |
| US9072874B2 (en) | 2011-05-13 | 2015-07-07 | Boston Scientific Scimed, Inc. | Medical devices with a heat transfer region and a heat sink region and methods for manufacturing medical devices |
| US9375234B2 (en) | 2006-12-15 | 2016-06-28 | Boston Scientific Scimed, Inc. | Medical device including structure for crossing an occlusion in a vessel |
| US9445784B2 (en) | 2005-09-22 | 2016-09-20 | Boston Scientific Scimed, Inc | Intravascular ultrasound catheter |
| US9808595B2 (en) | 2007-08-07 | 2017-11-07 | Boston Scientific Scimed, Inc | Microfabricated catheter with improved bonding structure |
| US9901706B2 (en) | 2014-04-11 | 2018-02-27 | Boston Scientific Scimed, Inc. | Catheters and catheter shafts |
| US11351048B2 (en) | 2015-11-16 | 2022-06-07 | Boston Scientific Scimed, Inc. | Stent delivery systems with a reinforced deployment sheath |
-
1996
- 1996-10-21 JP JP8277853A patent/JPH10118193A/en not_active Withdrawn
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11226131A (en) * | 1997-11-21 | 1999-08-24 | Sarcos Inc | Improved hybrid catheter guiding wire device |
| US8939916B2 (en) | 2002-07-25 | 2015-01-27 | Precision Vascular Systems, Inc. | Medical device for navigation through anatomy and method of making same |
| US8870790B2 (en) | 2002-07-25 | 2014-10-28 | Boston Scientific Scimed, Inc. | Medical device for navigation through anatomy and method of making same |
| US8900163B2 (en) | 2002-07-25 | 2014-12-02 | Precision Vascular Systems, Inc. | Medical device for navigation through anatomy and method of making same |
| US8915865B2 (en) | 2002-07-25 | 2014-12-23 | Precision Vascular Systems, Inc. | Medical device for navigation through anatomy and method of making same |
| US8932235B2 (en) | 2002-07-25 | 2015-01-13 | Precision Vascular Systems, Inc. | Medical device for navigation through anatomy and method of making same |
| US8936558B2 (en) | 2002-07-25 | 2015-01-20 | Precision Vascular Systems, Inc. | Medical device for navigation through anatomy and method of making same |
| US9023011B2 (en) | 2003-03-27 | 2015-05-05 | Boston Scientific Scimed, Inc. | Medical device |
| US9592363B2 (en) | 2003-03-27 | 2017-03-14 | Boston Scientific Scimed, Inc. | Medical device |
| US10207077B2 (en) | 2003-03-27 | 2019-02-19 | Boston Scientific Scimed, Inc. | Medical device |
| US9445784B2 (en) | 2005-09-22 | 2016-09-20 | Boston Scientific Scimed, Inc | Intravascular ultrasound catheter |
| US9375234B2 (en) | 2006-12-15 | 2016-06-28 | Boston Scientific Scimed, Inc. | Medical device including structure for crossing an occlusion in a vessel |
| US9808595B2 (en) | 2007-08-07 | 2017-11-07 | Boston Scientific Scimed, Inc | Microfabricated catheter with improved bonding structure |
| US9072874B2 (en) | 2011-05-13 | 2015-07-07 | Boston Scientific Scimed, Inc. | Medical devices with a heat transfer region and a heat sink region and methods for manufacturing medical devices |
| WO2014162393A1 (en) * | 2013-04-01 | 2014-10-09 | テルモ株式会社 | Guide wire |
| JP6082807B2 (en) * | 2013-04-01 | 2017-02-15 | テルモ株式会社 | Guide wire |
| US9901706B2 (en) | 2014-04-11 | 2018-02-27 | Boston Scientific Scimed, Inc. | Catheters and catheter shafts |
| US11351048B2 (en) | 2015-11-16 | 2022-06-07 | Boston Scientific Scimed, Inc. | Stent delivery systems with a reinforced deployment sheath |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A300 | Withdrawal of application because of no request for examination |
Free format text: JAPANESE INTERMEDIATE CODE: A300 Effective date: 20040106 |