JPH09274047A - Biochemclcal automatic analyzer dispensing apparatus for medical practice - Google Patents

Biochemclcal automatic analyzer dispensing apparatus for medical practice

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Publication number
JPH09274047A
JPH09274047A JP8120796A JP8120796A JPH09274047A JP H09274047 A JPH09274047 A JP H09274047A JP 8120796 A JP8120796 A JP 8120796A JP 8120796 A JP8120796 A JP 8120796A JP H09274047 A JPH09274047 A JP H09274047A
Authority
JP
Japan
Prior art keywords
container
liquid
amount
dispensing
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8120796A
Other languages
Japanese (ja)
Inventor
Takashi Hayashi
高 林
Katsuaki Takahashi
克明 高橋
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Ltd
Original Assignee
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Ltd filed Critical Hitachi Ltd
Priority to JP8120796A priority Critical patent/JPH09274047A/en
Publication of JPH09274047A publication Critical patent/JPH09274047A/en
Pending legal-status Critical Current

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  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

PROBLEM TO BE SOLVED: To obtain a dispensing apparatus in which the insertion amount of a nozzle can be controlled on the basis of the descent amount of a level due to the suction of a liquid even when an arbitrary container is used by installing a storage device or the like which stores the relationship between the residual amount of a liquid inside the container and the height of a level forum the bottom part of the container. SOLUTION: In a microcomputer 12, the descent position of every dispensing nozzle 4 in the suction operation of a liquid is converted into the height of a level from the bottom part of a container 2, and the relationship between the height of the level from the bottom part of the container 2 and a liquid amount inside the container 2 is stored in a storage device 13 on the basis of the accumulated value of the suction amount of the liquid. In this manner, data on an arbitrary container 2 is registered, the data on the container 2 is referred in an actual analysis, and the descent amount of the level after the suction operation of a designated liquid amount can be computed in the descent position of every dispensing nozzle 4. Thereby, the insertion amount into the level of every dispensing nozzle 4 can be controlled optimally, it is possible to prevent the air from being sucked or the liquid from being stuck to every dispensing nozzle 4 excessively, the liquid is dispensed precisely, and the residual amount of the liquid inside the container 2 can be computed.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【発明の属する技術分野】本発明は臨床用生化学自動分
析装置および分注装置に関する。
TECHNICAL FIELD The present invention relates to a clinical biochemical automatic analyzer and a dispensing device.

【0002】[0002]

【従来の技術】臨床用生化学自動分析装置では、一般に
試薬は試薬ボトルに、試料はサンプルカップまたは試験
管に収容し、それぞれを分注ノズルによって吸引して反
応容器に分注している。分析操作中、分注を繰り返すに
つれて容器内の試料もしくは試薬の残量が減少し、分注
量が不足したり全く分注ができなくなると分析結果に重
大な誤りが生じる。このような事態は医療現場において
致命的な事故となるため、残量不足の際には警告を発す
るか分注を行わないようにしている。
2. Description of the Related Art In a clinical biochemical automatic analyzer, a reagent is generally contained in a reagent bottle and a sample is contained in a sample cup or a test tube, and each is aspirated by a dispensing nozzle and dispensed into a reaction container. During the analytical operation, as the dispensing is repeated, the remaining amount of the sample or reagent in the container decreases, and when the dispensing amount becomes insufficient or the dispensing becomes impossible at all, a serious error occurs in the analysis result. Since such a situation causes a fatal accident in the medical field, when the remaining amount is insufficient, a warning is issued or no dispensing is performed.

【0003】このような事例の一つとして、特公平5−6
2305号公報に記載されている方法では、横断面積の一定
な容器を用いた場合に、一回の液面高さの測定後は、容
器内の液量と液面高さの比例関係を利用して、累積分注
量から液面高さを常時管理することによって事前に残液
不足の警告を発するようにしている。
As one of such cases, Japanese Patent Publication No. 5-6
In the method described in Japanese Patent No. 2305, when a container having a constant cross-sectional area is used, after the measurement of the liquid level once, the proportional relationship between the liquid amount in the container and the liquid level height is used. Then, the liquid level height is constantly managed from the accumulated dispensed amount so that a warning of insufficient remaining liquid is issued in advance.

【0004】[0004]

【発明が解決しようとする課題】臨床用生化学自動分析
装置では、試料および試薬の分注量が正確さを欠くこと
は重大な問題である。吸引の際、ノズルの液面への挿入
量が少ない場合には空気を吸引する恐れがあり、逆に多
過ぎる場合にはノズル外壁に付着した液が分注精度を狂
わせる原因になる。これは微量の液体を分注する際に顕
著に問題となる。そこで、容器内の液量の減少に伴って
下降する液面へのノズルの挿入量を制御する必要があ
る。特に半球面状の試験管底部等では液量の変化に対し
て液面の高さが急激に変化するため制御が難しい。この
ため、容器に固有な液面高さと残液量の関係を求める必
要がある。従来技術では、容器の断面形状が一定で、液
面高さと残液量の関係が既知であり、更に、あらかじめ
自動分析装置に登録されている容器しか分析に使用でき
ない。
In clinical biochemical automatic analyzers, it is a serious problem that the dispensed amounts of sample and reagent are inaccurate. At the time of suction, air may be sucked when the amount of insertion into the liquid surface of the nozzle is small, and conversely, when it is too large, the liquid adhering to the outer wall of the nozzle causes the dispensing accuracy to be disturbed. This is a significant problem when dispensing a small amount of liquid. Therefore, it is necessary to control the amount of nozzles inserted into the liquid surface that descends as the amount of liquid in the container decreases. In particular, at the bottom of a hemispherical test tube, etc., it is difficult to control because the height of the liquid surface changes rapidly in response to changes in the liquid amount. Therefore, it is necessary to find the relationship between the liquid level and the residual liquid amount, which is unique to the container. In the prior art, the cross-sectional shape of the container is constant, the relationship between the liquid level height and the residual liquid amount is known, and only the container registered in advance in the automatic analyzer can be used for analysis.

【0005】本発明の目的は、任意形状の容器内の液量
と液面高さとの関係を実測によって求めて記憶する機能
を分注装置に持たせ、これによって任意の容器を使用し
ても、それが一度実測を行い記憶されている容器であれ
ば、液体の吸引に伴う液面の下降量を予測してノズルの
挿入量を制御することを可能とし、更に、残液不足の警
告を確実に発することを可能にすることにある。
An object of the present invention is to provide a dispensing device with a function of memorizing a relationship between a liquid amount and a liquid surface height in a container having an arbitrary shape by actual measurement, so that even if an arbitrary container is used. If it is a container that has been measured and stored once, it is possible to control the amount of nozzle insertion by predicting the amount of liquid level drop due to liquid suction, and to warn of the remaining liquid shortage. It is to be able to emit surely.

【0006】[0006]

【課題を解決するための手段】上記問題点を解決するた
めに、本発明は液体の有無検知および容器底部の検知機
能を有する分注装置を用いて、分注ノズルが試料容器ま
たは試薬容器中の液体内へ下降し、液体を吸引するとい
う動作に際し、液面を検知するまでの分注ノズルの下降
量と一回当たりの液体の吸引量とをマイクロコンピュー
タへ送信する。更に、本動作を複数回に分割し、液体が
無くなり容器底部が検知されるまで繰り返し行う。
In order to solve the above problems, the present invention uses a dispensing device having a liquid presence detection function and a container bottom detection function, and a dispensing nozzle is provided in a sample container or a reagent container. In the operation of descending into the liquid and sucking the liquid, the descending amount of the dispensing nozzle until the liquid level is detected and the liquid sucking amount per time are transmitted to the microcomputer. Furthermore, this operation is divided into a plurality of times, and is repeated until the liquid runs out and the bottom of the container is detected.

【0007】自動分析装置のマイクロコンピュータは、
以上の動作により液体吸引時の分注ノズルの各下降位置
を容器底部からの高さへ変換し、これと液体の吸引量の
累積値から、容器底部からの液面の高さと容器内の液量
との関係を細分化したデータとして記憶する。
The microcomputer of the automatic analyzer is
By the above operation, each descending position of the dispensing nozzle at the time of liquid suction is converted into the height from the bottom of the container, and from this and the accumulated value of the suctioned amount of liquid, the height of the liquid surface from the bottom of the container and the liquid in the container The relationship with the quantity is stored as subdivided data.

【0008】上記手段により任意の容器のデータをマイ
クロコンピュータに登録した後、実際の分析に際して、
自動分析装置は、容器のデータを参照することにより、
分注ノズルが各下降位置において指定された液量を吸引
した後の液面の下降量を予め算出することができる。
After the data of an arbitrary container is registered in the microcomputer by the above means, in the actual analysis,
By referring to the container data, the automatic analyzer can
The descending amount of the liquid surface after the dispensing nozzle sucks the specified liquid amount at each descending position can be calculated in advance.

【0009】これにより、分注ノズルの液面への挿入量
を最適に制御し、空気の吸引もしくは分注ノズルへの液
体の過度の付着を防止して、正確な分注を行うことがで
きる。
This makes it possible to optimally control the amount of insertion of the dispensing nozzle into the liquid surface, prevent suction of air or excessive adhesion of the liquid to the dispensing nozzle, and perform accurate dispensing. .

【0010】また、分注ノズルが検知した液面の高さか
ら容器内の液体の残量を算出することが可能となり、必
要量の試料または試薬が残っていない場合には、これを
アラームとして表示することにより、オペレータが、そ
の試料に関する分析または、その試薬に関する項目の分
析が行えないことを認識することができる。
Further, it becomes possible to calculate the remaining amount of the liquid in the container from the height of the liquid level detected by the dispensing nozzle, and when the required amount of sample or reagent does not remain, this is used as an alarm. By displaying, the operator can recognize that the analysis regarding the sample or the item regarding the reagent cannot be performed.

【0011】[0011]

【発明の実施の形態】以下、図面を参照して本発明を詳
細に説明する。
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in detail with reference to the drawings.

【0012】図1は本発明の分注装置を用いて試料およ
び試薬の分注を実施する臨床用生化学自動分析装置の一
例を示す説明図である。また、図2は本自動分析装置に
装備される分注装置の斜視図である。更に、図3は断面
形状が複雑に変化する容器の一例を示す説明図である。
FIG. 1 is an explanatory view showing an example of a clinical biochemical automatic analyzer for dispensing a sample and a reagent using the dispenser of the present invention. Further, FIG. 2 is a perspective view of a dispensing device equipped in the automatic analyzer. Furthermore, FIG. 3 is an explanatory view showing an example of a container whose cross-sectional shape changes intricately.

【0013】本実施例では数種の試料容器2内に収容さ
れた試料、または数種の試薬容器3内に収容された試薬
中に、分注ノズル4を指定された順番で所定量だけ挿入
させて、各試料、または試薬をそれぞれ指定された量だ
け反応容器5内に分注する。全ての試料容器2または試
薬容器3はモータの回転軸に固定した試料ディスク6、
または試薬ディスク7上に同心円上に配置する。
In this embodiment, the dispensing nozzles 4 are inserted into the samples contained in the several kinds of sample containers 2 or the reagents contained in the several kinds of reagent containers 3 in a specified order by a predetermined amount. Then, each sample or reagent is dispensed into the reaction container 5 in a designated amount. All sample containers 2 or reagent containers 3 are sample disks 6 fixed to the rotary shaft of the motor,
Alternatively, they are arranged concentrically on the reagent disk 7.

【0014】分注装置8には、試料または試薬内に下降
し、液体を吸引する分注ノズル4が取り付けられてお
り、更に図2に示すように、分注ノズル4を容器2,3
内に挿入させる上下動用モータ17、及び容器2,3と
反応容器5との間を回転移動させるための回転用モータ
18が取り付けられている。
The dispensing device 8 is provided with a dispensing nozzle 4 that descends into a sample or a reagent and sucks a liquid. Further, as shown in FIG.
A vertical movement motor 17 to be inserted therein and a rotation motor 18 for rotationally moving between the containers 2 and 3 and the reaction container 5 are attached.

【0015】分注ノズル4と定量器9はチューブ10に
より接続されており、チューブ10内の流体を介して定
量器9の動作量に従った流体の移動が行われ、これによ
り所望の試料もしくは試薬の分注を行う。
The dispensing nozzle 4 and the metering device 9 are connected by a tube 10, and the fluid is moved according to the operation amount of the metering device 9 through the fluid in the tube 10, whereby a desired sample or Dispense reagents.

【0016】分注ノズル4の先端には、液面に接触した
ことを電気的に検知する電極を装備し、また分注ノズル
4が障害物に接触した場合に、その下降動作に伴ってノ
ズルが押し上げられたことを検知する接触検知器を設け
る。
The tip of the dispensing nozzle 4 is equipped with an electrode for electrically detecting the contact with the liquid surface, and when the dispensing nozzle 4 contacts an obstacle, the nozzle is moved along with the descending operation. A contact detector is provided to detect that the is pushed up.

【0017】また、指定した容器2,3から指定量の試
料、または試薬を反応容器5に分注するために、前述の
各モータ17,18をそれぞれ駆動するためのモータコ
ントローラ11を設ける。
Further, a motor controller 11 for driving each of the above-mentioned motors 17 and 18 is provided in order to dispense a specified amount of sample or reagent from the specified containers 2 and 3 into the reaction container 5.

【0018】さらに、これらのコントローラ11を同時
に制御して必要な一連の動作をさせるためにマイクロコ
ンピュータ12を設け、また、このマイクロコンピュー
タ12が必要とする情報を保持するための記憶装置13
を設ける。
Further, a microcomputer 12 is provided for controlling these controllers 11 at the same time to perform a necessary series of operations, and a storage device 13 for holding information required by the microcomputer 12.
Is provided.

【0019】また、オペレータに対して分析データをプ
リントアウトするプリンタ14と、装置の状態および機
能等を表示するモニタ15があり、更に各種分析依頼等
を入力するキーボード16を設ける。
There is also a printer 14 for printing out analysis data to the operator, a monitor 15 for displaying the status and functions of the apparatus, and a keyboard 16 for inputting various analysis requests and the like.

【0020】次に、図1に示す自動分析装置の分注装置
を用いて、任意の容器内の液体の残量と液面高さとの関
係を測定し、これを登録する動作について説明する。
Next, the operation of measuring the relationship between the liquid level and the liquid level in an arbitrary container using the dispensing apparatus of the automatic analyzer shown in FIG. 1 and registering the relationship will be described.

【0021】オペレータは、分析に使用する容器2,3
に導電性の液体を満たし、これを分析装置1にセットす
る。分注装置8は、回転用のモータ18を駆動し、容器
2,3上部に分注ノズル4を移動させる。
The operator uses the containers 2 and 3 used for the analysis.
Is filled with a conductive liquid, which is set in the analyzer 1. The dispensing device 8 drives the rotation motor 18 to move the dispensing nozzle 4 to the upper part of the containers 2 and 3.

【0022】続いて、上下動用のモータ17を駆動し、
分注ノズル4を容器2,3内の液体内に下降させる。分
注装置8は、分注ノズル4に取り付けられた液面検知電
極が液体に接触するまで下降し一旦停止する。ここで、
モータの回転数、すなわち、分注ノズル4の下降量をマ
イクロコンピュータ12へ送信する。その後分注装置8
は、再び上下動用モータを駆動し、液面検知電極の先端
が液面より下側(一例として1mm)の位置になるまで分
注ノズル4を追加下降させて停止する。
Subsequently, the vertical moving motor 17 is driven,
The dispensing nozzle 4 is lowered into the liquid in the containers 2 and 3. The dispensing device 8 descends and temporarily stops until the liquid level detection electrode attached to the dispensing nozzle 4 contacts the liquid. here,
The number of rotations of the motor, that is, the descending amount of the dispensing nozzle 4 is transmitted to the microcomputer 12. Then dispenser 8
Drives the vertical movement motor again, and further lowers the dispensing nozzle 4 until the tip of the liquid level detection electrode is located below the liquid level (1 mm as an example) and then stops.

【0023】この位置で定量器9を動作させ、容器2,
3内の液体を吸引する。吸引は、分注ノズル4の液面検
知電極が液面から離れるまで行う。ここで定量器9を停
止させ、この時の吸引量をマイクロコンピュータ12へ
送信する。
At this position, the quantifier 9 is operated and the container 2,
Aspirate the liquid in 3. Suction is performed until the liquid level detection electrode of the dispensing nozzle 4 separates from the liquid level. Here, the quantifier 9 is stopped, and the suction amount at this time is transmitted to the microcomputer 12.

【0024】液体の吸引を終えた分注ノズル4は、分注
装置8の上下動用モータ17により上昇し、更に、回転
用モータ18により分注ノズル4の洗浄位置まで移動す
る。洗浄位置で定量器9を作動させ、分注ノズル4内か
ら先に吸引した液体を廃液し、また、分注ノズル4の洗
浄を行う。
The dispensing nozzle 4 having finished sucking the liquid is lifted by the vertical movement motor 17 of the dispensing device 8 and further moved to the cleaning position of the dispensing nozzle 4 by the rotation motor 18. The metering device 9 is operated at the washing position to drain the liquid previously sucked from the inside of the dispensing nozzle 4 and to wash the dispensing nozzle 4.

【0025】この一連の動作を繰り返し行い、最終的に
容器2,3内の液体が無くなることによって、容器2,
3の底部に分注ノズル4が接触し、接触検知器により容
器底部が認識された時点で反復動作を終了し、この時点
での分注ノズル4の下降量をマイクロコンピュータ12
へ送信する。
By repeating this series of operations and finally eliminating the liquid in the containers 2 and 3,
When the dispensing nozzle 4 comes into contact with the bottom of the container 3 and the bottom of the container is recognized by the contact detector, the repetitive operation is terminated.
Send to

【0026】マイクロコンピュータ12は、液面を検知
するまでの分注ノズル4の下降量、容器底部を検知する
までの下降量、および、各吸引位置における液体の吸引
量とにより、各容器底部からの液面高さに従った液体の
残量を細分化したデータとして記憶装置13に記憶す
る。
The microcomputer 12 determines from the bottom of each container based on the amount of lowering of the dispensing nozzle 4 until the liquid level is detected, the amount of lowering until the container bottom is detected, and the liquid suction amount at each suction position. The remaining amount of liquid according to the liquid level is stored in the storage device 13 as subdivided data.

【0027】以上の一連の動作によって、オペレータに
より設置された任意の容器の、容器底部からの液面の高
さと容器内の液体の残量との関係を、本実施例では、1
mm刻みで測定し、記憶することができる。
By the series of operations described above, the relationship between the height of the liquid surface from the bottom of the container and the remaining amount of the liquid in the container of an arbitrary container installed by the operator is 1 in this embodiment.
It can be measured and stored in units of mm.

【0028】一例として、図3に示す容器のように、断
面形状が円柱・円錐・球面と変化することにより、単位
高さ当たりの容積が容器底部からの高さにより異なるよ
うな場合でも、それぞれの高さに応じた容積のデータを
実測により求め記憶することができる。
As an example, even in the case where the volume per unit height varies depending on the height from the bottom of the container as shown in the container shown in FIG. The data of the volume corresponding to the height of can be obtained by actual measurement and stored.

【0029】次に本機能を備えた、自動分析装置1の分
析時の動作について説明する。
Next, the operation of the automatic analyzer 1 having this function during analysis will be described.

【0030】オペレータは分析に先立ち前述の手順で任
意の容器2,3について液体の残量と容器底部からの高
さとの関係を測定し、あらかじめこれを自動分析装置1
に登録する。
Prior to the analysis, the operator measures the relationship between the remaining amount of liquid and the height from the bottom of the container in any of the containers 2 and 3 according to the above-mentioned procedure, and uses this in advance to analyze the relationship.
Register with.

【0031】実際の分析では、オペレータは、試料の分
析の依頼と共に、試料ディスク6上のどの位置にどの種
類の試料容器2が、また、試薬ディスク7上のどの位置
にどの種類の試薬容器3がそれぞれどの様な設置高さに
置かれていて、そこからどれだけの量を分注するのかを
キーボード16から自動分析装置1に入力する。
In the actual analysis, the operator requests the sample analysis, at which position on the sample disk 6 which type of sample container 2 and at which position on the reagent disk 7 which type of reagent container 3 should be placed. Inputs to the automatic analyzer 1 from the keyboard 16 what kind of installation height is set and how much amount is to be dispensed from.

【0032】分注動作開始後は、分注ノズル4が下降す
る度に容器内の液面の高さを検知する。分注ノズル4の
液面への挿入量が少ないと、吸引中にノズルが液面上に
出て空気を吸い込むため分注量が減少してしまう。ま
た、逆に挿入量が多すぎるとノズルの周りに液体が付着
して分注量が増加してしまう。そこで、吸引に際して
は、容器について登録されているデータを用いて、吸引
時に検知された液面高さで指定された量の液体を吸引し
た場合の液面の下降量を予め算出する。そして、この値
をもとに分注ノズル4の液面への挿入量を最適化し、ノ
ズルを追加下降させることにより、正確な量の分注を行
う。
After the dispensing operation is started, the height of the liquid surface in the container is detected every time the dispensing nozzle 4 descends. When the amount of the dispensing nozzle 4 inserted into the liquid surface is small, the nozzle comes out above the liquid surface and sucks air during suction, so that the dispensing amount decreases. On the other hand, if the insertion amount is too large, the liquid adheres to the periphery of the nozzle and the dispensing amount increases. Therefore, at the time of suction, the amount of lowering of the liquid level when the amount of liquid designated by the liquid level detected at the time of suction is sucked is calculated in advance using the data registered for the container. Then, based on this value, the insertion amount of the dispensing nozzle 4 into the liquid surface is optimized, and the nozzle is additionally lowered to dispense an accurate amount.

【0033】更に、自動分析装置1は、分注ノズル4の
下降量と試料容器2,試薬容器3の設置高さとから、容
器底部からの液面の高さに従った容器内の試料および試
薬の残量を計算して、これが所望の吸引量に満たない場
合には、事前に試料および試薬不足の警告を発し、分注
結果が正しくないことをモニタ15に表示し、また、プ
リンタ14からの分析データのプリントアウトにもその
旨印字し、オペレータに知らせる。
Further, the automatic analyzer 1 uses the descending amount of the dispensing nozzle 4 and the installation height of the sample container 2 and the reagent container 3 to determine the sample and the reagent in the container according to the height of the liquid surface from the bottom of the container. When the remaining amount of the sample is less than the desired suction amount, a warning of insufficient sample and reagent is issued in advance, the dispenser result is displayed on the monitor 15, and the printer 14 This is also printed on the printout of the analysis data of and the operator is notified.

【0034】このように、本実施例によれば、試料容器
および試薬容器の形状寸法が未知、または複雑に変化す
るような場合でも、実測に基づいてこれを決定して自動
分析装置に記憶・登録することによって、任意の容器を
使用しても、試料および試薬の正確な分注を行うことが
でき、なおかつ、試料および試薬の不足を正確に検知
し、オペレータに知らせることできる。
As described above, according to the present embodiment, even when the shape and size of the sample container and the reagent container are unknown or change intricately, this is determined based on the actual measurement and stored in the automatic analyzer. By registering, even if an arbitrary container is used, accurate dispensing of the sample and the reagent can be performed, and the shortage of the sample and the reagent can be accurately detected and notified to the operator.

【0035】[0035]

【発明の効果】本発明によれば、任意の容器内の液面高
さと残液量との関係を実測によって求め、これを登録・
保持することにより、液面検知位置から残液量と液量の
変化に伴う液面高さの変化量を算出することが可能とな
る。これによって任意の試料容器および試薬容器を使用
して、その任意の高さの液面において吸引を行っても正
確な分注を行うことが可能となる。
According to the present invention, the relationship between the liquid level in an arbitrary container and the residual liquid amount is determined by actual measurement, and this is registered / registered.
By holding the liquid level, it becomes possible to calculate the amount of change in the liquid surface height due to the change in the remaining liquid amount and the liquid amount from the liquid level detection position. This makes it possible to perform accurate dispensing by using an arbitrary sample container and reagent container and performing suction on the liquid surface at an arbitrary height.

【0036】さらに、任意の容器に対して残量不足を正
確に判定し、アラームを表示することが可能となる。
Furthermore, it becomes possible to accurately determine the remaining amount shortage for an arbitrary container and display an alarm.

【図面の簡単な説明】[Brief description of drawings]

【図1】本発明の実施例の動作の説明図。FIG. 1 is an explanatory diagram of an operation of an embodiment of the present invention.

【図2】本発明で使用する分注装置の斜視図。FIG. 2 is a perspective view of a dispensing device used in the present invention.

【図3】断面形状の変化する容器の説明図。FIG. 3 is an explanatory view of a container whose cross-sectional shape changes.

【符号の説明】[Explanation of symbols]

1…臨床用生化学自動分析装置、2…試料容器、3…試
薬容器、4…分注ノズル、5…反応容器、6…試料ディ
スク、7…試薬ディスク、8…分注装置、9…定量器、
10…チューブ、11…モータコントローラ、12…マ
イクロコンピュータ、13…記憶装置、14…プリン
タ、15…モニタ、16…キーボード。
1 ... Clinical biochemical automatic analyzer, 2 ... Sample container, 3 ... Reagent container, 4 ... Dispensing nozzle, 5 ... Reaction container, 6 ... Sample disc, 7 ... Reagent disc, 8 ... Dispensing device, 9 ... Fixed quantity vessel,
10 ... Tube, 11 ... Motor controller, 12 ... Microcomputer, 13 ... Storage device, 14 ... Printer, 15 ... Monitor, 16 ... Keyboard.

Claims (2)

【特許請求の範囲】[Claims] 【請求項1】試薬を添加して試料を反応させ、上記試料
の分析を行う臨床用生化学自動分析装置において、試料
容器および上記試薬容器内の液体の有無の検知手段と、
容器底部に接したことを検知する手段とを有した分注ノ
ズルを用い、液体を吸引しつつ液体の有無の検知を行
い、吸引されることによって下降する液面に追随して上
記分注ノズルを繰返し下降させることにより、任意の容
器内の液量の変化に従った液面高さの変化を測定し、そ
の結果をもとに該容器内の残液量と容器底部からの液面
高さとの関係を求めて記憶することを特徴とする分注装
置。
1. A clinical biochemical automatic analyzer for analyzing a sample by adding a reagent to the sample to detect the presence or absence of liquid in the sample container and the reagent container,
Using the dispensing nozzle having means for detecting contact with the bottom of the container, the presence or absence of the liquid is detected while sucking the liquid, and the dispensing nozzle is followed by the liquid surface descending by being sucked. By repeatedly lowering, measure the change in the liquid level height according to the change in the liquid amount in the arbitrary container, and based on the results, the residual liquid amount in the container and the liquid level height from the bottom of the container. A dispensing device characterized by finding and storing a relationship with.
【請求項2】請求項1に記載の上記分注装置を有し、任
意の容器を分析に使用しても、上記分注ノズルの液面へ
の挿入量を最適化して正確な分注を行うことを可能とす
ると共に、上記試料又は上記試薬の残量不足に対する警
告を発することを可能とする臨床用生化学自動分析装
置。
2. The dispenser having the dispenser according to claim 1, wherein even if an arbitrary container is used for analysis, the amount of the dispenser nozzle inserted into the liquid surface is optimized for accurate dispenser. A clinical biochemical automatic analyzer capable of performing a warning and issuing a warning for insufficient residual amount of the sample or the reagent.
JP8120796A 1996-04-03 1996-04-03 Biochemclcal automatic analyzer dispensing apparatus for medical practice Pending JPH09274047A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8120796A JPH09274047A (en) 1996-04-03 1996-04-03 Biochemclcal automatic analyzer dispensing apparatus for medical practice

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8120796A JPH09274047A (en) 1996-04-03 1996-04-03 Biochemclcal automatic analyzer dispensing apparatus for medical practice

Publications (1)

Publication Number Publication Date
JPH09274047A true JPH09274047A (en) 1997-10-21

Family

ID=13740050

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8120796A Pending JPH09274047A (en) 1996-04-03 1996-04-03 Biochemclcal automatic analyzer dispensing apparatus for medical practice

Country Status (1)

Country Link
JP (1) JPH09274047A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005017245A (en) * 2003-06-30 2005-01-20 Srl Inc Apparatus and system for detecting liquid level position of sample in test tube
JP2010096643A (en) * 2008-10-17 2010-04-30 Hitachi High-Technologies Corp Dispenser, specimen processor using the same, and automatic analyzer
EP3418750A1 (en) * 2017-06-22 2018-12-26 Siemens Healthcare Diagnostics Products GmbH Determining fill levels in vessels
JP2022009651A (en) * 2016-10-28 2022-01-14 ベックマン コールター, インコーポレイテッド Substance preparation evaluation system

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005017245A (en) * 2003-06-30 2005-01-20 Srl Inc Apparatus and system for detecting liquid level position of sample in test tube
JP2010096643A (en) * 2008-10-17 2010-04-30 Hitachi High-Technologies Corp Dispenser, specimen processor using the same, and automatic analyzer
JP2022009651A (en) * 2016-10-28 2022-01-14 ベックマン コールター, インコーポレイテッド Substance preparation evaluation system
EP3418750A1 (en) * 2017-06-22 2018-12-26 Siemens Healthcare Diagnostics Products GmbH Determining fill levels in vessels

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