JPH09227474A - Production of highly pure amino acid metal salt - Google Patents
Production of highly pure amino acid metal saltInfo
- Publication number
- JPH09227474A JPH09227474A JP3344296A JP3344296A JPH09227474A JP H09227474 A JPH09227474 A JP H09227474A JP 3344296 A JP3344296 A JP 3344296A JP 3344296 A JP3344296 A JP 3344296A JP H09227474 A JPH09227474 A JP H09227474A
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- metal salt
- acid metal
- solution
- carbonate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、殺菌、抗菌剤とし
て利用される、高純度アミノ酸金属塩の製造方法に関す
る。TECHNICAL FIELD The present invention relates to a method for producing a high-purity amino acid metal salt used as a bactericidal or antibacterial agent.
【０００２】[0002]
【従来の技術】従来より、銀や銅などの金属が殺菌作用
を有していることは知られている。例えば、銀などは硝
酸銀の水溶液の状態で殺菌、抗菌剤として利用されてい
る。しかし、硝酸銀水溶液を使用して繊維や紙に処理し
た場合、硝酸イオンの影響により、繊維あるいは紙が劣
化し、変色や強度の低下を引き起こす問題が発生する。
繊維や紙への上記影響や吸着性を改善する方法として、
アニオンとしてアミノ酸を利用したアミノ酸抗菌性金属
塩の水溶液が使用されている。通常、このアミノ酸抗菌
性金属塩の作製は、硝酸銀の溶液とアミノ酸のアルカリ
金属塩の水溶液を反応させることにより行っている。2. Description of the Related Art It has been conventionally known that metals such as silver and copper have a bactericidal action. For example, silver or the like is used as a bactericidal or antibacterial agent in the state of an aqueous solution of silver nitrate. However, when fibers or paper is treated with an aqueous solution of silver nitrate, the fibers or paper deteriorate due to the influence of nitrate ions, causing problems such as discoloration and reduction in strength.
As a method to improve the above influence and adsorption on fibers and paper,
An aqueous solution of an amino acid antibacterial metal salt using an amino acid as an anion is used. Usually, the amino acid antibacterial metal salt is produced by reacting a solution of silver nitrate with an aqueous solution of an alkali metal salt of amino acid.
【０００３】[0003]
【発明が解決しようとする課題】しかし、上記方法によ
り中間物質として得られるアミノ酸抗菌性金属塩は嵩が
高く、不純物である硝酸イオンなどのアニオンやアルカ
リ金属イオンなどのカチオンが残留しやすい。そのため
水洗を充分に行う必要があり、アミノ酸抗菌性金属塩の
収率が低下する。本発明の目的は、アミノ酸抗菌性金属
塩の水溶液の作製において、不純物含有量の少ない高純
度アミノ酸金属塩の製造方法を提供するところにある。However, the amino acid antibacterial metal salt obtained as an intermediate by the above method is bulky, and anions such as nitrate ions and cations such as alkali metal ions tend to remain. Therefore, it is necessary to sufficiently wash with water, and the yield of the amino acid antibacterial metal salt decreases. An object of the present invention is to provide a method for producing a high-purity amino acid metal salt having a low content of impurities in the production of an aqueous solution of an amino acid antibacterial metal salt.
【０００４】[0004]
【課題を解決するための手段】上記課題を解決するため
に、本発明はアミノ酸金属塩の溶液を作製する方法にお
いて、金属の炭酸塩を生成した後、ろ過して不純物イオ
ンを除去後この炭酸金属塩をアミノ酸により溶解するこ
とを特徴とするものであり、金属が、銀あるいは銅であ
ることを特徴とするものである。In order to solve the above-mentioned problems, the present invention relates to a method for preparing a solution of an amino acid metal salt, in which a metal carbonate is produced and then filtered to remove impurity ions. The metal salt is characterized by being dissolved by an amino acid, and the metal is characterized by being silver or copper.
【０００５】[0005]
【発明の実施の形態】本発明において、アミノ酸金属塩
の溶液を金属の炭酸塩を生成した後、アミノ酸溶液に溶
解しているが、これは、直接アミノ酸と金属から合成さ
れたアミノ酸金属塩は嵩高く、濾過性が大幅に低下する
ために、不純物である硝酸イオンやナトリウムイオンが
アミノ酸金属塩中に残留するのに比較して、金属塩の炭
酸塩は、緻密な結晶であり、濾過性も非常に良好なた
め、不純物イオンの残留が少なくなるためである。この
炭酸塩は、金属の硫酸塩、硝酸塩、塩化物などの易溶性
塩の水溶液中に、アルカリ金属の炭酸塩、炭酸水素塩な
どの水溶液を添加混合することにより作製することが可
能である。また、金属の炭酸塩をアミノ酸の水溶液で溶
解してアミノ酸金属塩の溶液を作製しているが、アミノ
酸の種類については、特に限定されるものではない。こ
れは処理する繊維や紙の種類により、最適なアミノ酸が
異なるためであり、グリシン、アラニン、グルタミン
酸、アスパラギン酸あるいはアシル化されたアミノ酸な
どが適用できる。BEST MODE FOR CARRYING OUT THE INVENTION In the present invention, a solution of an amino acid metal salt is dissolved in an amino acid solution after forming a metal carbonate. This is because an amino acid metal salt directly synthesized from an amino acid and a metal is Because of its bulkiness and significantly reduced filterability, the nitrates and sodium ions that are impurities remain in the amino acid metal salt, whereas the carbonate of the metal salt is a dense crystal and has a high filterability. Is also very good, and the amount of residual impurity ions is reduced. This carbonate can be prepared by adding and mixing an aqueous solution of an alkali metal carbonate, hydrogen carbonate or the like to an aqueous solution of a readily soluble salt such as a metal sulfate, a nitrate or a chloride. Further, although a metal carbonate is dissolved in an aqueous solution of an amino acid to prepare an amino acid metal salt solution, the type of amino acid is not particularly limited. This is because the optimum amino acid differs depending on the type of fiber or paper to be treated, and glycine, alanine, glutamic acid, aspartic acid, or an acylated amino acid can be applied.
【０００６】[0006]
【実施例】以下、本発明について実施例により詳細に説
明する。 （実施例１）１モル／ｌの硝酸銀溶液を５００ｍｌ、１
モル／ｌの炭酸水素ナトリウム溶液を５００ｍｌ作製
し、２５℃とした後、遮光した室内で硝酸銀溶液を攪拌
しながら炭酸水素ナトリウム溶液をゆっくりと添加し、
完全に添加後１０分間攪拌する。その後、生成した炭酸
銀をＮｏ．２の濾紙を用いて濾過を行い、５００ｍｌの
イオン交換水でレパルプ水洗を２回行う。このとき、濾
過時間は１分以内であり、非常に濾過性が良好であっ
た。その後、炭酸銀を真空乾燥機で４０℃で２４ｈｒ乾
燥を行い、炭酸銀の粉末６８．５ｇを得た。次に不純物
の含有量を調べるため、炭酸銀中のナトリウムイオンお
よび硝酸イオンの分析を行った。その結果、ナトリウム
イオンおよび硝酸イオンともに０．１％以下であり、不
純物が少なかった。この炭酸銀５．４ｇを、グルタミン
酸を５．９ｇ溶解した１リットルの溶液中に添加した。
その結果、グルタミン酸銀として１％の溶液を作製する
ことができた。EXAMPLES The present invention will be described in detail below with reference to examples. (Example 1) 500 ml of a 1 mol / l silver nitrate solution,
After preparing 500 ml of a mol / l sodium hydrogen carbonate solution at 25 ° C., slowly add the sodium hydrogen carbonate solution while stirring the silver nitrate solution in a light-shielded room.
After complete addition, stir for 10 minutes. Then, the generated silver carbonate was added to No. Filtration is performed using the No. 2 filter paper, and repulp water washing is performed twice with 500 ml of ion-exchanged water. At this time, the filtration time was within 1 minute, and the filterability was very good. Then, the silver carbonate was dried at 40 ° C. for 24 hours with a vacuum dryer to obtain 68.5 g of silver carbonate powder. Next, in order to examine the content of impurities, the sodium ion and nitrate ion in silver carbonate were analyzed. As a result, both sodium ions and nitrate ions were 0.1% or less, and impurities were small. 5.4 g of this silver carbonate was added to a 1-liter solution in which 5.9 g of glutamic acid was dissolved.
As a result, a 1% solution of silver glutamate could be prepared.
【０００７】（比較例１）１モル／ｌの硝酸銀溶液を５
００ｍｌ、１モル／ｌのグルタミン酸ナトリウム溶液を
５００ｍｌ作製し、２５℃とした後、遮光した室内で硝
酸銀溶液を攪拌しながらグルタミン酸ナトリウム溶液を
ゆっくりと添加し、完全に添加後１０分間攪拌する。そ
の後、生成したグルタミン酸銀をＮｏ．２の濾紙を用い
て濾過を行い、５０ｍｌのイオン交換水でレパルプ水洗
を２回行う。このとき、濾過時間は１時間以上必要であ
り、非常に濾過性が悪い状況であった。その後、グルタ
ミン酸銀を真空乾燥機で４０℃で２４ｈｒ乾燥を行い、
グルタミン酸銀の粉末８８ｇを得た。次に不純物の含有
量を調べるため、炭酸銀中のナトリウムイオンおよび硝
酸イオンの分析を行った。その結果、ナトリウムイオン
は０．３％であり、硝酸イオンは８％含有しており、不
純物が多くなっていた。(Comparative Example 1) 5 mol of 1 mol / l silver nitrate solution
After preparing 500 ml of 1 ml / l sodium glutamate solution of 100 ml and 25 ° C., the sodium glutamate solution is slowly added while stirring the silver nitrate solution in a light-shielded room, and after complete addition, the mixture is stirred for 10 minutes. Then, the produced silver glutamate was added to No. Filtration is performed using the filter paper of No. 2, and repulp water washing is performed twice with 50 ml of ion-exchanged water. At this time, the filtration time required 1 hour or more, and the filterability was very poor. After that, silver glutamate is dried in a vacuum dryer at 40 ° C. for 24 hours,
88 g of silver glutamate powder was obtained. Next, in order to examine the content of impurities, the sodium ion and nitrate ion in silver carbonate were analyzed. As a result, sodium ion was 0.3% and nitrate ion was 8%, and the amount of impurities was large.
【０００８】[0008]
【発明の効果】本発明によれば、不純物イオンの含有量
が少ない高純度のアミノ酸銀塩の溶液を作製することが
でき、被処理物の劣化や変色を少なくすることができ
る。According to the present invention, a highly pure amino acid silver salt solution containing a small amount of impurity ions can be prepared, and deterioration or discoloration of an object to be treated can be reduced.
Claims (1)
作製する方法に際して、銀あるいは銅の炭酸塩を生成し
た後、ろ過して不純物イオンを除去して得られた該炭酸
塩をアミノ酸に溶解することを特徴とする高純度アミノ
酸金属塩の製造方法。1. A method of producing an amino acid metal salt used as an antibacterial material, which comprises producing a silver or copper carbonate and then filtering the impurities to remove impurity ions and dissolving the obtained carbonate in the amino acid. A method for producing a high-purity amino acid metal salt, comprising:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3344296A JPH09227474A (en) | 1996-02-21 | 1996-02-21 | Production of highly pure amino acid metal salt |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3344296A JPH09227474A (en) | 1996-02-21 | 1996-02-21 | Production of highly pure amino acid metal salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH09227474A true JPH09227474A (en) | 1997-09-02 |
Family
ID=12386657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3344296A Pending JPH09227474A (en) | 1996-02-21 | 1996-02-21 | Production of highly pure amino acid metal salt |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH09227474A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022104606A (en) * | 2020-12-28 | 2022-07-08 | 株式会社キャスティングイン | Antibacterial coating agent |
-
1996
- 1996-02-21 JP JP3344296A patent/JPH09227474A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022104606A (en) * | 2020-12-28 | 2022-07-08 | 株式会社キャスティングイン | Antibacterial coating agent |
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