JPH09225029A - Injector and its manufacture - Google Patents

Injector and its manufacture

Info

Publication number
JPH09225029A
JPH09225029A JP8063714A JP6371496A JPH09225029A JP H09225029 A JPH09225029 A JP H09225029A JP 8063714 A JP8063714 A JP 8063714A JP 6371496 A JP6371496 A JP 6371496A JP H09225029 A JPH09225029 A JP H09225029A
Authority
JP
Japan
Prior art keywords
outer cylinder
gasket
injection
syringe
inner diameter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8063714A
Other languages
Japanese (ja)
Inventor
Keinosuke Isono
啓之介 磯野
Kazuya Araki
和也 荒木
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Material Engineering Technology Laboratory Inc
Original Assignee
Material Engineering Technology Laboratory Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Material Engineering Technology Laboratory Inc filed Critical Material Engineering Technology Laboratory Inc
Priority to JP8063714A priority Critical patent/JPH09225029A/en
Publication of JPH09225029A publication Critical patent/JPH09225029A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M2005/3132—Syringe barrels having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3134—Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3135—Syringe barrels characterised by constructional features of the proximal end

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

PROBLEM TO BE SOLVED: To enable previous mounting of an injection needle at an injection port without disturbing high pressure steam sterilization and filling of an injection agent into an outer cylinder with neary no mixed air by arranging the outer cylinder as a thermoplastic resin molded product with the inner diameter of a gasket insertion opening part larger than the inner diameter of a sliding part of the gasket. SOLUTION: An insertion opening part 2C of a gasket 4 of an outer cylinder 2 has its inner diameter L larger than the inner diameter M of a sliding part 2B of the gasket 4. More concretely, the insertion opening part 2C of the gasket 4 is a thermoplastic resin molded product which is formed by expanding gradually. Gradually tapered expansion is not necessary as the shape of the opening part 2C. It suffices that air in the outer cylinder 2 can escape from a gap between the gasket 4 and the inner wall of the outer cylinder 2 when the injection agent 6 is housed and sealed by the gasket 4. A plug body 5 is arranged at a sliding part 2B of the outer cylinder 2 spaced at an interval from an injection port 2A avoiding a ridge rib 11 and the injection agent 6 undergoes a steam sterilization to be housed into the outer cylinder 5 between the gasket 4 and the plug body 5.

Description

【発明の詳細な説明】Detailed Description of the Invention

【０００１】[0001]

【産業上の利用分野】本発明は、予め注射剤が充填され
た注射器に関するものであり、より詳細には、外筒への
注射剤の充填に際して、殆どエアが混入せず、高圧蒸気
滅菌に支障の生じない注射器及びその製造方法に関する
ものである。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a syringe pre-filled with an injection agent, and more specifically, it is suitable for high-pressure steam sterilization in which air is hardly mixed when the injection agent is filled into the outer cylinder. The present invention relates to a syringe that does not cause any trouble and a manufacturing method thereof.

【０００２】[0002]

【従来の技術】最近、医療事故を未然に防止するため
に、また院内感染等を極力防止するために、予め滅菌又
は無菌状態で外筒内に薬剤又は薬液等の注射剤が充填さ
れたプレフィールドシリンジと一般に称される注射器が
提案されている。また、かかるプレフィールドシリンジ
には二医薬成分以上の注射剤がその注射時まで分離して
充填されている多成分用注射器も提案されている。2. Description of the Related Art In recent years, in order to prevent medical accidents and to prevent hospital-acquired infections and the like as much as possible, sterile or aseptic pre-filled syringes have been filled with injections such as drugs or medicinal solutions. Syringes, commonly referred to as field syringes, have been proposed. In addition, a multi-component syringe in which an injection of two or more pharmaceutical ingredients is separately filled in the prefield syringe until the injection is also proposed.

【０００３】従来、注射器には、外筒の射出口部に密閉
キャップが装着され、外筒の基端挿入開口からはプラン
ジャーのガスケットが挿入され、かかるガスケット内に
注射剤が収容されている。そして、注射剤を外筒内に充
填する場合は、先ずガスケットが外筒内に所定の位置ま
で挿入され、次に、外筒の射出口から注射剤が充填さ
れ、充填後に密閉キャップが射出口に装着される。かか
る状態で注射器が高圧蒸気滅菌にかけられる。この場
合、注射剤は外筒の射出口から充填するため、外筒内に
エアが殆どない状態で充填することができる。Conventionally, a syringe has a sealing cap attached to the injection port of an outer cylinder, a gasket of a plunger is inserted from a base end insertion opening of the outer cylinder, and an injectable agent is contained in the gasket. . And when filling the injection into the outer cylinder, first the gasket is inserted into the outer cylinder to a predetermined position, then the injection is filled from the injection port of the outer cylinder, and after the filling, the sealing cap is opened. Be attached to. In this state, the syringe is subjected to autoclaving. In this case, since the injection is filled from the injection port of the outer cylinder, the injection can be filled with almost no air in the outer cylinder.

【０００４】[0004]

【発明が解決しようとする課題】しかしながら、従来の
注射器では、外筒の射出口に密閉キャップを備えている
ため、予め注射針を射出口に取り付けることができな
い。このため、注射器の使用時には病院での注射針の取
付操作を要し、院内感染のおそれが生じる。また、二成
分用注射器などでは、ガスケットと栓体との間に注射液
を充填するため、ガスケットの挿入開口から注射液を充
填するが、エアなどの外筒内に残存するという不都合が
あり、このようなエアの残存状態で注射器の高圧蒸気滅
菌を行うと、外筒内にエアにより圧力差が生じ、熱可塑
性樹脂外筒を変形させるという問題がある。However, in the conventional syringe, since the injection port of the outer cylinder is provided with the sealing cap, the injection needle cannot be attached to the injection port in advance. Therefore, when the syringe is used, it is necessary to attach the injection needle in the hospital, which may cause hospital infection. In addition, in a two-component syringe or the like, since the injection liquid is filled between the gasket and the plug body, the injection liquid is filled from the insertion opening of the gasket, but there is a disadvantage that air or the like remains in the outer cylinder, When high-pressure steam sterilization of a syringe is performed in such a state where air remains, there is a problem that a pressure difference is caused by air in the outer cylinder and the outer cylinder of the thermoplastic resin is deformed.

【０００５】従って、本発明の目的は、外筒への注射剤
の充填に際して、殆どエアが混入せず、高圧蒸気滅菌に
支障の生じない、しかも予め射出口に注射針を取り付け
て置くことのできる注射器及びその製造方法を提供する
ことにある。Therefore, an object of the present invention is to prevent air from being mixed in the outer cylinder when it is filled with an injectable agent, which does not hinder high-pressure steam sterilization, and in which an injection needle is previously attached to the injection port. An object of the present invention is to provide a syringe and a manufacturing method thereof.

【０００６】[0006]

【課題を解決するための手段】本発明は、予め外筒内に
注射剤が収容される注射器において、上記外筒は、ガス
ケットの挿入開口部の内径（Ｌ）が該ガスケットの摺動
部の内径（Ｍ）より大径に形成された熱可塑性樹脂成形
物であることを特徴とする注射器を提供することによ
り、上記目的を達成したものである。本発明はまた、上
記注射器において、上記注射剤を上記ガスケットの挿入
開口から上記外筒内に充填し、且つ上記挿入開口部の内
径（Ｌ）の形成位置より上位の液位まで満たし、次に、
上記ガスケットを上記開口の上方から挿入して上記注射
剤を液密に上記外筒内に充填し、その後、上記外筒と共
に注射剤を高圧蒸気滅菌することを特徴とする注射器の
製造方法を提供することにより、上記目的を達成したも
のである。SUMMARY OF THE INVENTION The present invention provides a syringe in which an injection agent is previously housed in an outer cylinder, wherein the outer cylinder has an inner diameter (L) of a gasket insertion opening part of a sliding part of the gasket. The above object is achieved by providing a syringe characterized by being a thermoplastic resin molded product having a diameter larger than the inner diameter (M). The present invention also provides the above-mentioned syringe, wherein the injection is filled from the insertion opening of the gasket into the outer cylinder and a liquid level higher than a position where the inner diameter (L) of the insertion opening is formed, ,
A method for manufacturing a syringe, characterized in that the gasket is inserted from above the opening to liquid-tightly fill the outer cylinder with the injection agent, and then the injection agent is sterilized by high-pressure steam with the outer tube. By doing so, the above object is achieved.

【０００７】[0007]

【作用】上記注射器の外筒では、例えば図３に示す状態
で外筒内に注射剤を充填し、上方からガスケットを挿入
していくと、図４に示す如く、外筒内のエアは末広がり
の開口の側壁から逃げ出ることができ、注射剤を末広が
りの開始位置より多少高い位値に液位があれば、注射剤
はガスケットから微量はみ出した状態で外筒内に液密に
充填され、この結果、殆どのエアが外筒内から除かれる
ことなる。また、このようなガスケットの挿入開口を介
して注射剤を充填する方法では、図１に示す如く射出口
に密閉キャップを設ける必要はなく、外筒内に開放可能
な栓体を配して射出口等に予め注射針を取り付けること
ができる。In the outer cylinder of the above syringe, for example, when the outer cylinder is filled with the injection agent in the state shown in FIG. 3 and the gasket is inserted from above, the air in the outer cylinder spreads toward the end as shown in FIG. If it is possible to escape from the side wall of the opening of the injection, and the liquid level is a little higher than the starting position of the end spread, the injection is liquid-tightly filled in the outer cylinder with a slight amount protruding from the gasket, As a result, most of the air is removed from the inside of the outer cylinder. Moreover, in the method of filling the injection through the insertion opening of such a gasket, it is not necessary to provide a sealing cap at the injection port as shown in FIG. An injection needle can be attached to the outlet or the like in advance.

【０００８】[0008]

【実施例】以下、本発明に係る注射器の好ましい実施例
を添付図面を参照しながら詳述する。図１は本発明の注
射器の第一実施例の側断面図、図２は図１のＩ−Ｉ線に
沿った注射器の断面図、図３（Ａ）及び（Ｂ）は図１の
注射器の組立途中の側断面図、図４は図１の注射器の組
立途中の側断面図、図５及び図６は第一実施例における
注射器の使用時の側断面図である。DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Preferred embodiments of a syringe according to the present invention will be described below in detail with reference to the accompanying drawings. 1 is a side sectional view of a first embodiment of the syringe of the present invention, FIG. 2 is a sectional view of the syringe taken along the line I-I of FIG. 1, and FIGS. 3A and 3B are of the syringe of FIG. FIG. 4 is a side sectional view during assembly, FIG. 4 is a side sectional view during assembly of the syringe of FIG. 1, and FIGS. 5 and 6 are side sectional views during use of the syringe in the first embodiment.

【０００９】図１〜図６に示す第一実施例の注射器１
は、予め外筒内に注射剤が収容される注射器であり、外
筒２は、ガスケット４の挿入開口部２Ｃの内径（Ｌ）が
ガスケット４の摺動部２Ｂの内径（Ｍ）より大径に形成
された熱可塑性樹脂成形物である。即ち、本実施例のガ
スケット４の挿入開口部２Ｃは末広がりに形成されてい
る。The syringe 1 of the first embodiment shown in FIGS.
Is a syringe in which an injection agent is stored in advance in the outer cylinder, and in the outer cylinder 2, the inner diameter (L) of the insertion opening 2C of the gasket 4 is larger than the inner diameter (M) of the sliding portion 2B of the gasket 4. It is a thermoplastic resin molded product formed in. That is, the insertion opening 2C of the gasket 4 of this embodiment is formed so as to widen toward the end.

【００１０】本実施例の注射器１を更に説明すると、本
実施例の注射器１の外筒２は、熱可塑性樹脂の成形物
で、射出成形により成形される。外筒２には予め注射針
７がセットされるため、外筒２の奥部には栓体５が配さ
れ、栓体５に開放機能を持たせるため後述する凸条リブ
１１が形成されている。熱可塑性樹脂成形物としては、
例えば、低密度或は高密度ポリエチレン、ポリプロピレ
ン、ポリブタジエン−１等のポリオレフィン類、ポリ塩
化ビニル、ポリ塩化ビニリデン、塩化ビニリデン共重合
体、ポリメタクリル酸メチル、ポリビニルアルコール、
エチレン−ビニルアルコール共重合体、アクリロニトリ
ル共重合体、ポリエチレンテレフタレート等を挙げるこ
とができる。特に、ポリオレフィン類は汎用性及び薬剤
に影響を与えない点で好ましく、更には非晶質の環状の
オレフィンコポリマー等の高いガラス転移温度を有し比
重が１．０〜１．１のものが望ましい。具体的には、光
デイスク基板、光学レンズなどの材料として最近用いら
れている商標名ゼオネックス（日本ゼオン株式会社）、
商標名アペル（三井石油化学工業株式会社）等のポリオ
レフィン系樹脂である。To further explain the syringe 1 of this embodiment, the outer cylinder 2 of the syringe 1 of this embodiment is a molded product of a thermoplastic resin and is formed by injection molding. Since the injection needle 7 is set in the outer cylinder 2 in advance, the plug body 5 is arranged in the inner portion of the outer cylinder 2, and the convex rib 11 to be described later is formed to give the plug body 5 an opening function. There is. As the thermoplastic resin molded product,
For example, low density or high density polyethylene, polypropylene, polyolefins such as polybutadiene-1, polyvinyl chloride, polyvinylidene chloride, vinylidene chloride copolymer, polymethyl methacrylate, polyvinyl alcohol,
Examples thereof include ethylene-vinyl alcohol copolymer, acrylonitrile copolymer, and polyethylene terephthalate. In particular, polyolefins are preferable from the viewpoint of versatility and chemicals, and those having a high glass transition temperature such as an amorphous cyclic olefin copolymer and a specific gravity of 1.0 to 1.1 are desirable. . Specifically, the brand name ZEONEX (Nippon Zeon Co., Ltd.), which is recently used as a material for optical disc substrates, optical lenses, etc.,
A polyolefin resin such as the trademark Apel (Mitsui Petrochemical Industry Co., Ltd.).

【００１１】栓体５は、射出口２Ａから一定間隔あけて
ガスケット４側に設けられ、栓体５と射出口２Ａとの間
の外筒２部分の内側壁には、外筒２の軸方向に延びる凸
条リブ１１、１１・・・が形成され、栓体５が射出口２
Ａに達する際に、凸条リブ１１、１１・・・により栓体
５の外周壁が弾性変形して注射剤６が射出口２Ａに流通
する空隙が形成される。ガスケット４及び栓体５は外筒
２の内壁と液密を保つ程度の弾性体を有するものであれ
ば良い。具体的にはゴム製のガスケット及びゴム栓が用
いられる。The plug 5 is provided on the gasket 4 side with a certain distance from the injection port 2A, and the inner wall of the outer cylinder 2 portion between the plug 5 and the injection port 2A has an axial direction of the outer cylinder 2. The ribs 11, 11 ...
When reaching A, the outer peripheral wall of the plug body 5 is elastically deformed by the convex ribs 11, 11 ... And a void is formed in which the injection 6 flows into the injection port 2A. The gasket 4 and the plug 5 may be any as long as they have an elastic body that maintains liquid tightness with the inner wall of the outer cylinder 2. Specifically, a rubber gasket and a rubber stopper are used.

【００１２】栓体５と射出口２Ａとの間の外筒２の内壁
面における複数の凸条リブ１１は、外筒２の軸方向に向
かって形成される。即ち、凸条リブ１１は外筒２の成形
時の型抜き方向とほぼ同一の方向に向けて形成される。
また、凸条リブ１１の数は、１以上、好ましくは３以
上、更に好ましく５以上である。また凸条リブ１１が複
数形成される場合は、点対称の配置がなされても良い
し、また外筒の一部の内壁面に偏らせて形成しても良
い。また凸条リブ１１は外筒２の先端奥部に向かって徐
々に***したテーパ頂部１１Ａとなっている。テーパは
必ずしも必要ではない。しかし、かかるテーパ頂部１１
Ａの形成は、成形の型抜き時に型などの影響を受けず、
スムースに型を抜くことができ、また、注射器１の使用
時に栓体５が外筒２の奥深くスムースに挿入することが
できる。A plurality of convex ribs 11 on the inner wall surface of the outer cylinder 2 between the plug body 5 and the injection port 2A are formed in the axial direction of the outer cylinder 2. That is, the ribs 11 are formed in a direction substantially the same as the die cutting direction when the outer cylinder 2 is molded.
The number of the ribs 11 is 1 or more, preferably 3 or more, and more preferably 5 or more. When a plurality of convex ribs 11 are formed, they may be arranged symmetrically with respect to each other, or may be formed so as to be biased to a part of the inner wall surface of the outer cylinder. Further, the convex rib 11 is a tapered top portion 11A that gradually rises toward the inner end of the outer cylinder 2. The taper is not always necessary. However, such taper top 11
The formation of A is not affected by the mold or the like when the mold is removed.
The mold can be smoothly removed, and the plug 5 can be smoothly inserted deep into the outer cylinder 2 when the syringe 1 is used.

【００１３】図２に示す如く本実施例では外筒２の凸条
リブ頂部１１Ａの最大高さ（ｗ）は１ｍｍである。凸条
リブ頂部１１Ａの最大高さ（ｗ）は、外筒の内径（Ｍ）
によって好ましい範囲が決定され、凸条リブ頂部１１Ａ
の最大高さ（ｗ）が外筒の内径（Ｍ）の１／５０〜１／
５倍であることが好ましい。凸条リブ頂部１１Ａの最大
高さ（ｗ）が上記範囲を下回ると、外筒２の外周壁と栓
体５の内周壁との間に充分な空隙１２ができないおそれ
があり、上記範囲を上回ると、栓体５の摺動性が悪くな
る。また、本実施例の外筒２の射出口２Ａが形成される
肩部１３の内壁には、複数の突起部１４が形成され、突
起部１４により、外筒２の内側壁と栓体５の外周壁との
空隙１２を流れる注射剤６を射出口２Ａに導くための通
路が突起部１４間に形成される。かかる通路は、必ずし
も必要はないが、栓体５が完全に肩部１３の内周面に密
着して注射剤６の流出通路が塞がれるのを防止してい
る。従って、突起部１４を形成する代わりに、肩部１３
の内壁面に溝状部を形成して射出口２Ａまでの通路を確
保しても良い。As shown in FIG. 2, in this embodiment, the maximum height (w) of the convex rib tops 11A of the outer cylinder 2 is 1 mm. The maximum height (w) of the convex rib top 11A is the inner diameter (M) of the outer cylinder.
The preferred range is determined by the convex rib top 11A.
Maximum height (w) is 1/50 to 1 / of the inner diameter (M) of the outer cylinder
Preferably it is 5 times. If the maximum height (w) of the convex rib top portion 11A is less than the above range, there is a possibility that a sufficient gap 12 may not be formed between the outer peripheral wall of the outer cylinder 2 and the inner peripheral wall of the plug body 5, and the maximum height (w) exceeds the above range. Then, the slidability of the plug body 5 deteriorates. Further, a plurality of protrusions 14 are formed on the inner wall of the shoulder portion 13 in which the injection port 2A of the outer cylinder 2 of the present embodiment is formed, and the protrusions 14 allow the inner wall of the outer cylinder 2 and the plug 5 to be separated. A passage is formed between the protrusions 14 for guiding the injection 6 flowing through the space 12 between the outer peripheral wall and the injection port 2A. Although such a passage is not always necessary, the stopper 5 is prevented from completely adhering to the inner peripheral surface of the shoulder portion 13 and blocking the outflow passage of the injection 6. Therefore, instead of forming the protrusion 14, the shoulder 13
A groove portion may be formed on the inner wall surface of the to secure a passage to the injection port 2A.

【００１４】外筒２のガスケット４の挿入開口部２Ｃ
は、その内径（Ｌ）がガスケット４の摺動部２Ｂの内径
（Ｍ）より大径に形成されている。本実施例では具体的
に、ガスケット４の挿入開口部２Ｃは末広がりに形成さ
れている。開口部２Ｃの形状はテーパ状の末広がりであ
る必要はなく、ガスケット４で注射剤６を密封収容する
際に、外筒２内のエアがガスケット４と外筒２内壁との
間から逃げ出すようになっていればよい。従って、内径
（Ｌ）と内径（Ｍ）との間にエアが逃げ出す差がある限
り段差形成されたものでも良い。栓体５は凸条リブ１１
を避けて、射出口２Ａから一定間隔あけてガスケット４
側に配せられ、ガスケット４は最終的に外筒２の摺動部
２Ｂに配されている。ガスケット４と栓体５との間の外
筒２内には注射剤６が蒸気滅菌されて収容されている。Insertion opening 2C of the gasket 4 of the outer cylinder 2
Has an inner diameter (L) larger than the inner diameter (M) of the sliding portion 2B of the gasket 4. In this embodiment, specifically, the insertion opening 2C of the gasket 4 is formed so as to widen toward the end. The shape of the opening 2C does not need to be a tapered divergent shape, and when the injection agent 6 is hermetically stored in the gasket 4, the air in the outer cylinder 2 escapes from between the gasket 4 and the inner wall of the outer cylinder 2. It should be. Therefore, a step may be formed as long as there is a difference in air escape between the inner diameter (L) and the inner diameter (M). The plug body 5 is a convex rib 11
To avoid the gasket 4 with a certain space from the injection port 2A.
The gasket 4 is finally arranged on the sliding portion 2B of the outer cylinder 2. The injection 6 is steam-sterilized and accommodated in the outer cylinder 2 between the gasket 4 and the stopper 5.

【００１５】次に、上記注射器１の製造方法を説明する
と、先ず、射出成形により外筒２に末広がりの挿入開口
部２Ｃ、凸条リブ１１、及び突起部１４を正確に形成す
る。この場合、挿入開口部２Ｃが末広がりであり、且つ
凸条リブ１１が外筒２の軸方向でしかもテーパ状に形成
されるため、外筒２を歪ませることなく正確に型抜き成
形でき、特に、上述の非晶質のポリオレフィンにおいて
正確な成形ができる。図３（Ａ）に示す如く、成形外筒
２の先端に注射針７を取付け、外筒２に栓体５を挿入す
る。栓体５は形成凸条リブ１１から約栓体５幅分を空け
て配する。図３（Ｂ）に示す如く、注射剤６をガスケッ
ト４の挿入開口２Ｃから外筒２内に充填し、且つ上記挿
入開口部の大径な内径（Ｌ）の形成位置Ｓより上位の液
位Ｈまで満たす。Next, the method of manufacturing the syringe 1 will be described. First, the insertion opening 2C, the ridge rib 11, and the protrusion 14 that spread out toward the end are accurately formed in the outer cylinder 2 by injection molding. In this case, the insertion opening 2C is widened toward the end, and the convex ribs 11 are formed in a taper shape in the axial direction of the outer cylinder 2, so that the outer cylinder 2 can be accurately die-molded without being distorted. Accurate molding is possible with the above-mentioned amorphous polyolefin. As shown in FIG. 3A, the injection needle 7 is attached to the tip of the molded outer cylinder 2, and the plug 5 is inserted into the outer cylinder 2. The plug body 5 is arranged with a width of about 5 from the formed convex rib 11. As shown in FIG. 3 (B), the injection agent 6 is filled into the outer cylinder 2 through the insertion opening 2C of the gasket 4, and the liquid level higher than the position S where the large inner diameter (L) of the insertion opening is formed. Fill up to H.

【００１６】次に、図４に示す如くガスケット４を開口
部２Ｃの上方から挿入して注射剤６を液密に外筒２内に
充填する。この場合、注射剤６液位表面のエアは、ガス
ケット４の降下と共に、ガスケット４の外壁と外筒２の
内壁の隙間を通って逃げ出し、エアが残存しない状態で
注射剤６が充填される。これは、挿入開口部２Ｃの大径
な内径（Ｌ）と摺動部２Ｂの内径（Ｍ）の差により達成
されるものである。このようなエアの残留状態で注射剤
６が収容されると、高圧蒸気滅菌時等の外部と内部とに
差圧が生じる場合でも、外筒２内はエアによる膨縮変化
が殆ど見られないので、熱可塑性樹脂の外筒２を熱変形
させてしまう虞がない。このため、使用時にガスケット
４の摺動性に問題が生じない。ガスケット４を図１に示
す如く摺動部２Ｂまで押し下げた後、外筒２と共に注射
剤６を高圧蒸気滅菌する。尚、高圧蒸気滅菌に際しては
ガスケット４にプランジャー３を取付ておいても良い。
高圧蒸気滅菌は、１０５℃〜１４０℃、特に好ましくは
１０５℃〜１２５℃の範囲で蒸気滅菌することが望まし
い。かかる範囲であれば、滅菌が確実になされる一方、
外筒２などの熱変形のおそれが少なくなる。Next, as shown in FIG. 4, the gasket 4 is inserted from above the opening 2C to fill the outer cylinder 2 with the injection 6 in a liquid-tight manner. In this case, the air on the liquid level surface of the injection 6 escapes through the gap between the outer wall of the gasket 4 and the inner wall of the outer cylinder 2 as the gasket 4 descends, and the injection 6 is filled without air remaining. This is achieved by the difference between the large inner diameter (L) of the insertion opening 2C and the inner diameter (M) of the sliding portion 2B. When the injection agent 6 is stored in such a state where air remains, even if a pressure difference between the outside and the inside occurs during high-pressure steam sterilization, almost no expansion or contraction change due to air is seen in the outer cylinder 2. Therefore, there is no possibility that the outer cylinder 2 made of a thermoplastic resin will be thermally deformed. Therefore, there is no problem in the slidability of the gasket 4 during use. After the gasket 4 is pushed down to the sliding portion 2B as shown in FIG. 1, the injection 6 together with the outer cylinder 2 is sterilized under high pressure steam. The plunger 3 may be attached to the gasket 4 during the high-pressure steam sterilization.
High-pressure steam sterilization is preferably carried out by steam sterilization at 105 ° C to 140 ° C, particularly preferably 105 ° C to 125 ° C. Within such a range, sterilization will be ensured, while
The risk of thermal deformation of the outer cylinder 2 and the like is reduced.

【００１７】次に図１、図５及び図６に従って本実施例
の注射器１の使用を説明すると、図１の注射器の状態か
ら図５に示す状態までプランジャー３を押し込む。この
場合、プランジャー３の押し込みにより栓体５が連動し
射出口２Ａ側に押し込まれ、栓体５の外周壁には凸状リ
ブ１１が食い込む。これにより、栓体５の外周壁が変形
し、栓体５の外周壁と外筒２の内壁との間に空隙が生
じ、栓体５とガスケット４との間の注射剤６が空隙を介
して射出口２Ａ側に流入可能となる。かかる状態でプラ
ンジャー３の押し込みをコントロールしながら外筒２内
の全てのエアを押し出したのち、注射針７を患者に刺通
する。図６に示す如くプランジャー３を完全に押し込
み、患者への注射剤６の投与が完了する。このようなガ
スケットの挿入開口を介して注射剤を充填する方法で
は、図１に示す如く射出口に密閉キャップを設ける必要
はなく、外筒２内に開放可能な栓体５を配して射出口等
に予め注射針７を取り付けることができる。Next, the use of the syringe 1 of this embodiment will be described with reference to FIGS. 1, 5 and 6, and the plunger 3 is pushed in from the state of the syringe of FIG. 1 to the state shown in FIG. In this case, when the plunger 3 is pushed in, the plug 5 is interlocked and pushed toward the injection port 2A side, and the convex rib 11 bites into the outer peripheral wall of the plug 5. As a result, the outer peripheral wall of the stopper 5 is deformed, and a gap is created between the outer peripheral wall of the stopper 5 and the inner wall of the outer cylinder 2, and the injection 6 between the stopper 5 and the gasket 4 passes through the gap. And can flow into the injection port 2A side. In this state, while controlling the pushing of the plunger 3, all the air in the outer cylinder 2 is pushed out, and then the injection needle 7 is pierced into the patient. As shown in FIG. 6, the plunger 3 is completely pushed in to complete the administration of the injection 6 to the patient. In the method of filling the injection through the insertion opening of the gasket as described above, it is not necessary to provide a sealing cap at the injection port as shown in FIG. The injection needle 7 can be attached to the outlet or the like in advance.

【００１８】次に、図７乃至図１０に従って本発明の第
二実施例の注射器について説明する。 図７は本発明の
注射器の第二実施例の側断面図である。図８〜図１０は
第二実施例の注射器のプランジャーを押し込ませた状態
を示す側断面図である。図７〜図１０に示す第一実施例
の二液成分用注射器２１は、先端部に注射針７が取り付
けられる射出口２Ａを有した外筒２と、ガスケット４が
取り付けられて外筒２に嵌入されるプランジャー３とか
らなり、また外筒２内の先端奥部に栓体５を配して射出
口２Ａを塞ぎ栓体５とガスケット４との間に注射剤６
Ａ、６Ｂが液密充填されている点で、第一実施例の注射
器１とほぼ同様な部材及び構造なので、かかる部材につ
いては第一実施例の注射器１と同一の符号を賦してその
詳しい説明を省略する。また、注射器２１の外筒２は熱
可塑性樹脂の成形物であり、栓体５は、射出口２Ａから
一定間隔あけてガスケット４側に設けられ、栓体５と射
出口２Ａとの間の外筒２部分の内側壁には、外筒２の軸
方向に延びる凸条リブ１１、１１・・・が形成されてい
る点でも、第一実施例の注射器１とほぼ同様な部材及び
構造なので、かかる部材については第一実施例の注射器
１と同一の符号を賦してその詳しい説明を省略する。Next, the syringe of the second embodiment of the present invention will be explained with reference to FIGS. FIG. 7 is a side sectional view of the second embodiment of the syringe of the present invention. 8 to 10 are side sectional views showing a state in which the plunger of the syringe of the second embodiment is pushed in. The two-component syringe 21 of the first embodiment shown in FIGS. 7 to 10 has an outer cylinder 2 having an injection port 2A at the tip of which an injection needle 7 is attached, and a gasket 4 attached to the outer cylinder 2. The plunger 3 is inserted into the outer cylinder 2, and the stopper 5 is arranged in the inner portion of the distal end of the outer cylinder 2 to close the injection port 2A and the injection 6 between the stopper 5 and the gasket 4.
Since A and 6B are liquid-tightly filled and have substantially the same members and structures as those of the syringe 1 of the first embodiment, the same reference numerals as those of the syringe 1 of the first embodiment are given to these members and the details thereof will be given. The description is omitted. Further, the outer cylinder 2 of the syringe 21 is a molded product of a thermoplastic resin, and the plug body 5 is provided on the gasket 4 side with a certain distance from the injection port 2A, and is provided outside the space between the plug body 5 and the injection port 2A. Since the ribs 11, 11, ... That extend in the axial direction of the outer cylinder 2 are formed on the inner wall of the cylinder 2 portion, the members and the structure are substantially the same as the syringe 1 of the first embodiment. Such members are given the same reference numerals as those of the syringe 1 of the first embodiment, and detailed description thereof will be omitted.

【００１９】図７に示す如く注射器２１が注射器１と異
なる点は、外筒２の挿入開口部２Ｃが肉薄に形成され、
摺動部２Ｂの内径（Ｍ）より大径な内径（Ｌ）に形成さ
れている。また挿入開口部２Ｃの大径部の形成開始位置
はテーパ面２３で形成され、ガスケット４が摺動部２Ｂ
に挿入案内されやすくなっている。また外筒２内のガス
ケット４及び栓体５との間に仕切り栓体２２が設けら
れ、仕切り栓体２２を境にそれぞれ異なる成分の注射剤
６Ａ、６Ｂが充填されている。栓体５と射出口２Ａとの
間の外筒２の内壁面には、第一実施例の注射器１と同様
な長めの複数の凸条リブ１１が外筒２の軸方向に向かっ
て形成されている。また凸条リブ１１の形成位置または
その長さは、栓体５が弾性変形して栓体５又は仕切り栓
体２２の外周壁と外筒２の内壁とに空隙が形成される位
置により決定される。As shown in FIG. 7, the syringe 21 differs from the syringe 1 in that the insertion opening 2C of the outer cylinder 2 is formed thin.
The inner diameter (L) is larger than the inner diameter (M) of the sliding portion 2B. Further, the formation start position of the large diameter portion of the insertion opening 2C is formed by the tapered surface 23, and the gasket 4 is formed by the sliding portion 2B.
It is easy to be inserted and guided in. Further, a partition plug body 22 is provided between the gasket 4 and the plug body 5 in the outer cylinder 2, and the partition plug body 22 is filled with injection agents 6A and 6B having different components. On the inner wall surface of the outer tube 2 between the plug body 5 and the injection port 2A, a plurality of elongated ribs 11 having the same length as the syringe 1 of the first embodiment are formed in the axial direction of the outer tube 2. ing. The formation position of the convex rib 11 or the length thereof is determined by the position where the plug body 5 is elastically deformed and a gap is formed between the outer peripheral wall of the plug body 5 or the partition plug body 22 and the inner wall of the outer cylinder 2. It

【００２０】注射器２１の外筒２は、従来より長く成形
される。仕切り栓体２２はガスケット４及び栓体５と同
様に外筒２の内壁と液密を保つ程度の弾性を有するもの
であれば良い。具体的にはゴム製のガスケット及びゴム
栓と同様なものが用いられる。栓体５と仕切り栓体２２
の間には注射剤６Ａが収容され、仕切り栓体２２とガス
ケット４の間には注射剤６Ｂが収容されている。例えば
本実施例では注射剤６Ａは局部麻酔剤等であり、注射剤
６Ｂは痛みを伴う注射剤である。注射剤６Ａ、６Ｂの滅
菌は高圧蒸気滅菌がなされており、これ以外にも無菌充
填などが可能であるが、滅菌を確実にするには高圧蒸気
滅菌が望ましい。高圧蒸気滅菌は、温度が１０５℃〜１
４０℃の範囲であるが、特に、温度が１０５℃〜１２５
℃の範囲であることが望ましい。かかる範囲であれば、
外筒２に熱・圧による変形が生じ難い。The outer cylinder 2 of the syringe 21 is formed longer than before. As with the gasket 4 and the plug 5, the partition plug 22 may be elastic enough to maintain liquid tightness with the inner wall of the outer cylinder 2. Specifically, the same material as the rubber gasket and the rubber stopper is used. Plug 5 and partition plug 22
The injection agent 6A is accommodated in the space between them, and the injection agent 6B is accommodated between the partition plug body 22 and the gasket 4. For example, in this embodiment, the injection 6A is a local anesthetic, and the injection 6B is a painful injection. High-pressure steam sterilization is performed for sterilization of the injections 6A and 6B, and aseptic filling can be performed in addition to this, but high-pressure steam sterilization is desirable to ensure sterilization. High-pressure steam sterilization has a temperature of 105 ° C to 1
It is in the range of 40 ° C., but especially when the temperature is 105 ° C. to 125 ° C.
It is desirable to be in the range of ° C. Within this range,
The outer cylinder 2 is unlikely to be deformed by heat and pressure.

【００２１】次に、上記注射器２１の製造方法を説明す
ると、先ず、射出成形により挿入開口部２Ｃと共に凸条
リブ１１、及び突起部１４を外筒２に正確に形成する。
外筒２に栓体５を所定の深さまで挿入し、注射剤６Ａを
液位が開口部２Ｃの大径内径部に達するまで充填する。
注射剤６Ａの充填後、仕切り栓体２２を上部から外筒２
内にエアが残留しない状態で所定の深さまで挿入する。
これにより、栓体５も同時に一定の深さまで移動する。
次に注射剤６Ｂを外筒２内に充填し、注射剤６Ｂを液位
が開口部２Ｃの大径内径部に達するまで充填する。その
充填後、ガスケット４を外筒２内にエアが残留しない状
態で挿入する。そして、ガスケット４にプランジャー４
を取付け、射出口２Ａにプロテクター付の注射針７を取
付ける。かかる状態で、注射器２１を高圧蒸気滅菌して
注射剤６Ａ、６Ｂを滅菌する。Next, the method of manufacturing the syringe 21 will be described. First, the protruding rib 11 and the projection 14 are accurately formed on the outer cylinder 2 together with the insertion opening 2C by injection molding.
The stopper 5 is inserted into the outer cylinder 2 to a predetermined depth, and the injection 6A is filled until the liquid level reaches the large diameter inner diameter portion of the opening 2C.
After filling the injection 6A, the partition plug 22 is inserted from the upper part to the outer cylinder 2
Insert it to the specified depth with no air remaining inside.
As a result, the plug body 5 also moves to a certain depth at the same time.
Next, the injection 6B is filled in the outer cylinder 2, and the injection 6B is filled until the liquid level reaches the large diameter inner diameter portion of the opening 2C. After the filling, the gasket 4 is inserted into the outer cylinder 2 in a state where no air remains. Then, the plunger 4 is attached to the gasket 4.
Then, the injection needle 2 with a protector is attached to the injection port 2A. In this state, the syringe 21 is sterilized by high-pressure steam to sterilize the injections 6A and 6B.

【００２２】次に、本実施例の二液成分用注射器２１を
用いて注射するには、図７の状態からプランジャー３が
押し込まれ、注射剤６Ａ、６Ｂを介して栓体５及び仕切
り栓体２２が図８の位置まで押し込まれる。図８の位置
まで押し込まれると、栓体５の外周壁と外筒２の内壁と
の間に空隙が形成され、栓体５はプランジャー３の押し
込みがあっても移動が停止する。従って、注射剤６Ａが
一旦急激に空間部９９に流入されるが、針先７まで達す
ることがないため漏れでない。空間部９９のエアを追い
出した後、注射剤６Ａが患者に注射投与される。図９の
位置まで仕切り栓体２２がプランジャー３により押し込
まれると、仕切り栓体２２の外周壁と外筒２の内壁との
間に空隙が形成され、仕切り栓体２２はプランジャー３
の押し込みがあっても移動が停止する。そして、注射剤
６Ｂが射出口２Ａ側に流入され、プランジャー３が更に
押し込まれ、患者の体内に注射投与される。従って、先
に局部麻酔剤が患者に投与され、痛みを麻痺させた状態
で、痛みを伴う注射剤６Ｂを投与することができる。Next, for injection using the two-component syringe 21 of this embodiment, the plunger 3 is pushed in from the state shown in FIG. 7, and the stopper 5 and the partition stopper are inserted through the injections 6A and 6B. The body 22 is pushed to the position shown in FIG. When pushed to the position shown in FIG. 8, a gap is formed between the outer peripheral wall of the plug 5 and the inner wall of the outer cylinder 2, and the plug 5 stops moving even if the plunger 3 is pushed. Therefore, the injection 6A is suddenly flown into the space 99, but does not reach the needle tip 7 and does not leak. After the air in the space 99 is expelled, the injection 6A is injected and administered to the patient. When the partition plug body 22 is pushed by the plunger 3 to the position shown in FIG. 9, a space is formed between the outer peripheral wall of the partition plug body 22 and the inner wall of the outer cylinder 2, and the partition plug body 22 is fixed to the plunger 3
The movement stops even if is pressed. Then, the injection agent 6B is flown into the ejection port 2A side, the plunger 3 is further pushed, and is injected into the patient's body. Therefore, the local anesthetic is first administered to the patient, and the painful injection 6B can be administered while the pain is paralyzed.

【００２３】[0023]

【発明の効果】以上説明したように本発明の注射器にお
いて、上記外筒は、ガスケットの挿入開口部の内径
（Ｌ）が該ガスケットの摺動部の内径（Ｍ）より大径に
形成された熱可塑性樹脂成形物であるので、また上記注
射剤を上記ガスケットの挿入開口から上記外筒内に充填
し、且つ上記挿入開口部の内径（Ｌ）の形成位置より上
位の液位まで満たし、次に、上記ガスケットを上記開口
の上方から挿入して上記注射剤を液密に上記外筒内に充
填し、その後、上記外筒と共に注射剤を高圧蒸気滅菌す
るので、外筒への注射剤の充填に際して、殆どエアが混
入せず、高圧蒸気滅菌に支障の生じない、しかも予め射
出口に注射針を取り付けて置くことのできる。As described above, in the syringe of the present invention, the outer cylinder is formed such that the inner diameter (L) of the insertion opening of the gasket is larger than the inner diameter (M) of the sliding portion of the gasket. Since it is a thermoplastic resin molded product, the injection is filled into the outer cylinder through the insertion opening of the gasket, and is filled up to a liquid level higher than the position where the inner diameter (L) of the insertion opening is formed. In the above, the gasket is inserted from above the opening to liquid-tightly fill the injection in the outer cylinder, and thereafter, the injection is sterilized by high-pressure steam together with the outer cylinder. At the time of filling, almost no air is mixed in, the high-pressure steam sterilization is not hindered, and an injection needle can be attached to the injection port in advance.

【図面の簡単な説明】[Brief description of drawings]

【図１】本発明の注射器の第一実施例の側断面図であ
る。FIG. 1 is a side sectional view of a first embodiment of a syringe of the present invention.

【図２】図１のＩ−Ｉ線に沿った注射器の断面図であ
る。2 is a cross-sectional view of the syringe taken along line I-I of FIG.

【図３】（Ａ）及び（Ｂ）は図１の注射器の組立途中の
側断面図である。3A and 3B are side cross-sectional views of the injector of FIG. 1 during assembly.

【図４】図１の注射器の組立途中の側断面図である。FIG. 4 is a side sectional view of the syringe of FIG. 1 during assembly.

【図５】第一実施例における注射器の使用時の側断面図
である。FIG. 5 is a side sectional view of the syringe according to the first embodiment when in use.

【図６】第一実施例における注射器の使用時の側断面図
である。FIG. 6 is a side sectional view of the syringe in use according to the first embodiment.

【図７】本発明の注射器の第二実施例の側断面図であ
る。FIG. 7 is a side sectional view of a second embodiment of the syringe of the present invention.

【図８】第二実施例の注射器のプランジャーを押し込ま
せた状態を示す側断面図である。FIG. 8 is a side sectional view showing a state where the plunger of the syringe of the second embodiment is pushed in.

【図９】第二実施例の注射器のプランジャーを押し込ま
せた状態を示す側断面図である。FIG. 9 is a side sectional view showing a state where the plunger of the syringe of the second embodiment is pushed in.

【図１０】第二実施例の注射器のプランジャーを押し込
ませた状態を示す側断面図である。FIG. 10 is a side sectional view showing a state where the plunger of the syringe of the second embodiment is pushed in.

【符号の説明】[Explanation of symbols]

１、２１ 注射器 ２ 外筒 ２Ａ 外筒の射出口 ２Ｃ 挿入開口部 ３ プランジャー ４ ガスケット ５ 栓体 ６ 注射液 ７ 注射針 １１ 凸条リブ １３ 外筒の肩部 １４ 突起部 1, 21 Syringe 2 Outer cylinder 2A Outlet of outer cylinder 2C Insertion opening 3 Plunger 4 Gasket 5 Plug 6 Injection liquid 7 Injection needle 11 Convex rib 13 Outer cylinder shoulder 14 Projection

Claims (2)

【特許請求の範囲】[Claims] 【請求項１】 予め外筒内に注射剤が収容される注射器
において、上記外筒は、ガスケットの挿入開口部の内径
（Ｌ）が該ガスケットの摺動部の内径（Ｍ）より大径に
形成された熱可塑性樹脂成形物であることを特徴とする
注射器。1. In a syringe in which an injection agent is contained in advance in an outer cylinder, the outer cylinder has an inner diameter (L) of a gasket insertion opening portion larger than an inner diameter (M) of a sliding portion of the gasket. A syringe characterized by being a formed thermoplastic resin article. 【請求項２】 上記請求項１記載の注射器において、上
記注射剤を上記ガスケットの挿入開口から上記外筒内に
充填し、且つ上記挿入開口部の大径な内径（Ｌ）の形成
位置より上位の液位まで満たし、 次に、上記ガスケットを上記開口の上方から挿入して上
記注射剤を液密に上記外筒内に充填し、その後、上記外
筒と共に注射剤を高圧蒸気滅菌することを特徴とする注
射器の製造方法。2. The syringe according to claim 1, wherein the injection agent is filled in the outer cylinder through an insertion opening of the gasket, and is higher than a position where a large inner diameter (L) of the insertion opening is formed. To the liquid level, and then insert the gasket from above the opening to fill the injection in a liquid-tight manner in the outer cylinder, and then sterilize the injection with the outer cylinder with high pressure steam. A method for manufacturing a characteristic syringe.
JP8063714A 1996-02-26 1996-02-26 Injector and its manufacture Pending JPH09225029A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8063714A JPH09225029A (en) 1996-02-26 1996-02-26 Injector and its manufacture

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8063714A JPH09225029A (en) 1996-02-26 1996-02-26 Injector and its manufacture

Publications (1)

Publication Number Publication Date
JPH09225029A true JPH09225029A (en) 1997-09-02

Family

ID=13237338

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8063714A Pending JPH09225029A (en) 1996-02-26 1996-02-26 Injector and its manufacture

Country Status (1)

Country Link
JP (1) JPH09225029A (en)

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JP2008500861A (en) * 2004-05-28 2008-01-17 シラグ・ゲーエムベーハー・インターナショナル Injection device
US8834419B2 (en) 2008-06-19 2014-09-16 Cilag Gmbh International Reusable auto-injector
US8845594B2 (en) 2008-06-19 2014-09-30 Cilag Gmbh International Auto-injector with filling means
US8939958B2 (en) 2008-06-19 2015-01-27 Cilag Gmbh International Fluid transfer assembly for a syringe
US8968236B2 (en) 2005-04-06 2015-03-03 Cilag Gmbh International Injection device
US9028451B2 (en) 2006-06-01 2015-05-12 Cilag Gmbh International Injection device
US9028453B2 (en) 2008-06-19 2015-05-12 Cilag Gmbh International Reusable auto-injector
US9072833B2 (en) 2006-06-01 2015-07-07 Cilag Gmbh International Injection device
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US9649441B2 (en) 2005-04-06 2017-05-16 Cilag Gmbh International Injection device (bayonet cap removal)
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US9895493B2 (en) 2004-05-28 2018-02-20 Cilag Gmbh International Injection device
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US9649441B2 (en) 2005-04-06 2017-05-16 Cilag Gmbh International Injection device (bayonet cap removal)
US8968236B2 (en) 2005-04-06 2015-03-03 Cilag Gmbh International Injection device
US9358346B2 (en) 2005-08-30 2016-06-07 Cilag Gmbh International Needle assembly for a prefilled syringe system
US9770558B2 (en) 2005-09-27 2017-09-26 Cilag Gmbh International Auto-injection device with needle protecting cap having outer and inner sleeves
JPWO2007099870A1 (en) * 2006-02-28 2009-07-16 久光製薬株式会社 Syringe
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US9028453B2 (en) 2008-06-19 2015-05-12 Cilag Gmbh International Reusable auto-injector
US8939958B2 (en) 2008-06-19 2015-01-27 Cilag Gmbh International Fluid transfer assembly for a syringe
US8845594B2 (en) 2008-06-19 2014-09-30 Cilag Gmbh International Auto-injector with filling means
US10709849B2 (en) 2013-06-11 2020-07-14 Cilag Gmbh International Guide for an injection device
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