JPH05345718A - Whitening cosmetic composition - Google Patents
Whitening cosmetic compositionInfo
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- JPH05345718A JPH05345718A JP5037586A JP3758693A JPH05345718A JP H05345718 A JPH05345718 A JP H05345718A JP 5037586 A JP5037586 A JP 5037586A JP 3758693 A JP3758693 A JP 3758693A JP H05345718 A JPH05345718 A JP H05345718A
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- cosmetic composition
- whitening cosmetic
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Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は、ユリ科植物(Liliacea
e) の成分を含有し、紫外線による皮膚の黒化、又はシ
ミ、ソバカス等の色素沈着を消失し、又は予防するため
の美白化粧料組成物に関する。BACKGROUND OF THE INVENTION The present invention relates to a lily plant (Liliacea
The present invention relates to a whitening cosmetic composition containing the component (e) for eliminating or preventing blackening of skin due to ultraviolet rays or pigmentation such as spots and freckles.
【０００２】[0002]
【従来の技術】従来、日焼け等の外界の刺激に起因して
皮膚の表面に発生するシミ、ソバカス等を薄くする美白
化粧料組成物としては、ビタミンＣ及びその誘導体、ア
ルブチン、コウジ酸等のメラニン生成抑制物質を用いた
ものが知られていた。2. Description of the Related Art Conventionally, as a whitening cosmetic composition for thinning spots, freckles and the like generated on the surface of the skin due to external stimuli such as sunburn, vitamin C and its derivatives, arbutin, kojic acid, etc. The thing using the melanin production inhibitor was known.
【０００３】しかし、ビタミンＣ類及びアルブチンは多
水分系において酸化されやすく不安定であり、変色、変
臭の原因となりがちであった。However, vitamin C's and arbutin are easily oxidized in a high water content system and are unstable, and tend to cause discoloration and odor.
【０００４】また、コウジ酸は少量では皮膚の黒化を防
止する効果が小さい等、美白化粧料の有効成分としてい
ずれも充分なものとは言い難い。Further, kojic acid is not sufficient as an active ingredient of a whitening cosmetic composition, since a small amount of kojic acid has a small effect of preventing blackening of the skin.
【０００５】[0005]
【発明が解決しようとする課題】本発明の目的は、上述
のような現状に鑑み、美白作用に対して強い活性を有
し、しかも、安全性の点でも心配のない天然物系の美白
化粧料組成物を提供することにあった。SUMMARY OF THE INVENTION In view of the above-mentioned circumstances, an object of the present invention is a natural product-type whitening makeup which has a strong activity against whitening action and is safe in terms of safety. To provide a food composition.
【０００６】[0006]
【課題を解決するための手段】本発明者らは、種々の植
物抽出エキスについてメラニン産生抑制作用を指標とし
て色素細胞の淡色化を検討した結果、ユリ科植物の成分
のうちのある種のものが色素細胞に対し著しい白色化作
用を有することを見出し本発明を完成するに至った。[Means for Solving the Problems] As a result of examining the lightening of pigment cells using various plant extract extracts as an indicator of the melanin production inhibitory effect, the present inventors have found that some of the components of Liliaceae plants Have been found to have a remarkable whitening effect on pigment cells, and have completed the present invention.
【０００７】本発明に係る美白化粧料組成物は、ユリ科
植物の成分のうち、中間極性を有する有機溶媒、一価若
しくは多価の低級アルコール、又はこれらの混合物に可
溶性を示すものを有効成分とするものである。The whitening cosmetic composition according to the present invention is an active ingredient which is soluble in an organic solvent having an intermediate polarity, a monohydric or polyhydric lower alcohol, or a mixture thereof among the components of the Liliaceae plant. It is what
【０００８】エンレイソウは、ユリ科エンレイソウ属に
属する植物であって、これまでは根茎を芋児七と称し
て、降圧剤又は鎮痛薬（民間薬）として使われていた。The trillium is a plant belonging to the genus Trillium of the family Liliaceae, and the rhizome has been used as an antihypertensive drug or an analgesic (folk medicine) until now called rhizome.
【０００９】本発明に係る美白化粧料組成物には、上記
有効成分のほか、賦活剤、結合剤、希釈剤等の任意の製
剤化用補助成分を混合させることができる。In addition to the above-mentioned active ingredients, the whitening cosmetic composition according to the present invention may be mixed with optional auxiliary ingredients for formulation such as an activator, a binder and a diluent.
【００１０】本発明に係る美白化粧料組成物は、油溶性
エキスであって水に不溶であるから、液状の製剤とする
場合、適当な油脂、プロピレングリコール、グリセリン
モノステアレート等に溶解させるか、エタノールに溶解
させた後、界面活性剤を用いて水中油型エマルジョンと
することができる。剤型は、軟膏剤、乳剤、クリーム等
の任意のものとすることができる。Since the whitening cosmetic composition according to the present invention is an oil-soluble extract and is insoluble in water, when it is made into a liquid preparation, is it dissolved in an appropriate fat, propylene glycol, glycerin monostearate or the like? After being dissolved in ethanol, an oil-in-water emulsion can be prepared by using a surfactant. The dosage form can be any of ointments, emulsions, creams and the like.
【００１１】本発明の美白化粧料組成物は、中間極性を
有する有機溶媒で抽出処理し、抽出液から溶媒を留去す
ることによって得ることができる。このような抽出溶媒
として好ましいものは、例えば、ベンゼン、エチルエー
テル、クロロホルム、酢酸エチル、酢酸ブチル、塩化メ
チレン、アセトン等がある。これらの溶媒は、メタノー
ル、エタノール、１，３−ブチレングリコール等の低級
アルコールと混合して用いることもできる。The whitening cosmetic composition of the present invention can be obtained by performing an extraction treatment with an organic solvent having an intermediate polarity and distilling the solvent off from the extract. Preferred examples of such an extraction solvent include benzene, ethyl ether, chloroform, ethyl acetate, butyl acetate, methylene chloride, and acetone. These solvents can also be used as a mixture with lower alcohols such as methanol, ethanol and 1,3-butylene glycol.
【００１２】本発明に係る美白化粧料組成物を抽出する
場合には、その他の抽出条件は任意に定めることができ
る。例えば、原料のエンレイソウを約１〜３０倍量程度
の抽出溶媒に常温又は加熱下に浸漬するだけで目的を達
することができる。When extracting the whitening cosmetic composition according to the present invention, other extraction conditions can be arbitrarily determined. For example, the objective can be achieved simply by immersing the starting material trillium in an extraction solvent in an amount of about 1 to 30 times at room temperature or under heating.
【００１３】抽出液は、濾過または遠心分離により固型
物を除去した後、適当な方法で抽出溶媒を除去し、濃
縮、乾燥することができる。本発明の美白化粧料組成物
は、上記の抽出液の段階で活性炭で脱色したり、合成高
分子吸着体等の樹脂処理により精製することができる
が、本発明の美白作用は抽出物のままでも強く現れるの
で、色、臭い、安定性等の点で不都合がない限り、高度
の精製は通常不必要である。The extract can be concentrated or dried by removing the solid matter by filtration or centrifugation and then removing the extraction solvent by an appropriate method. The whitening cosmetic composition of the present invention can be decolorized with activated carbon at the stage of the above-mentioned extract or purified by resin treatment such as a synthetic polymer adsorbent, but the whitening effect of the present invention remains as an extract. However, since it appears strongly, high-level purification is usually unnecessary unless there is a problem in terms of color, odor, stability and the like.
【００１４】本発明の美白化粧料組成物においては、有
効成分の好ましい配合量は、剤型、期待されるメラニン
産生抑制効果の程度などによっても異なるが、通常0.00
1 〜1.0％程度、より好ましくは 0.01 〜 0.5％程度が
適当である。In the whitening cosmetic composition of the present invention, the preferable amount of the active ingredient is usually 0.00 although it varies depending on the dosage form, the expected degree of melanin production inhibiting effect and the like.
Appropriately about 1 to 1.0%, more preferably about 0.01 to 0.5%.
【００１５】本発明の美白化粧料組成物には、その種類
に応じ性能を損なわない範囲において適宜公知の成分を
配合することができる。例えば、従来から使用されてい
るメラニン産生抑制剤（ビタミンＣ、胎盤抽出物）、紫
外線散乱剤、紫外線吸収剤、抗炎症剤等を配合すること
ができる。The whitening cosmetic composition of the present invention may be blended with known components as appropriate depending on the type thereof, as long as the performance is not impaired. For example, conventionally used melanin production inhibitors (vitamin C, placenta extract), ultraviolet scattering agents, ultraviolet absorbing agents, anti-inflammatory agents and the like can be added.
【００１６】[0016]
【実施例】以下に本発明の美白化粧料組成物の試験例及
び実施例を掲げて本発明を更に詳しく説明する。EXAMPLES The present invention will be described in more detail below with reference to test examples and examples of the whitening cosmetic composition of the present invention.
【００１７】試験例１ メラニン産生色素細胞（B16 mouse melanoma) に対する
白色化効果をみた。試験物質はエンレイソウの根茎の
メタノール抽出エキス（参考例１のもの）、試験物質
はチュウリップの花のメタノール抽出エキス（参考例５
のもの）、試験物質はハナスゲの全草のメタノール抽
出エキス（参考例６のもの）、試験物質はジャノヒゲ
全草のメタノール抽出エキス（参考例７のもの）、試験
物質はチトセラン全草のメタノール抽出エキス（参考
例８のもの）対照物質は甘草エキス、対照物質はア
ルブチン、対照物質はコウジ酸色素細胞は培養細胞と
して確立されている B-16 マウスメラノーマ細胞Test Example 1 The whitening effect on melanin-producing pigment cells (B16 mouse melanoma) was observed. The test substance is a methanol extract of rhizome of trillium (of reference example 1), and the test substance is a methanol extract of chrysanthemum flower (reference example 5).
Test substance is the methanol extract of the whole plant of Rana japonicus (reference example 6), the test substance is the methanol extract of the whole plant of Johigeh bean (of reference example 7), the test substance is the methanol extract of whole plant of cytocelan. Extract (of Reference Example 8) Control substance is licorice extract, control substance is arbutin, control substance is kojic acid pigment cells established as cultured cells B-16 mouse melanoma cells
【００１８】試験方法 クリーンベンチ内において培養フラスコ(25cm2) に、牛
胎児血清 1ml、イーグル最少栄養培地 9mlを添加し、そ
こに３×104 個の色素細胞をまき、炭酸ガス培養器にお
いて5%の炭酸ガスを含有する空気下37℃で培養した。細
胞が付着したところで、フラスコに試料を、各々最終濃
度が１μg/ml、３μg/ml、５μg/ml、10μg/mlになるよ
うに添加し、３日間培養した。なお、コントロールは試
料を添加せず培養した。Test Method In a clean bench, 1 ml of fetal bovine serum and 9 ml of Eagle's minimal nutrient medium were added to a culture flask (25 cm 2 ), and 3 × 10 4 pigment cells were sprinkled on the culture flask, followed by 5 in a carbon dioxide incubator. Incubation was carried out at 37 ° C. in the air containing carbon dioxide gas (%). When the cells were attached, the samples were added to the flask so that the final concentrations were 1 μg / ml, 3 μg / ml, 5 μg / ml, and 10 μg / ml, and the cells were cultured for 3 days. The control was cultured without adding the sample.
【００１９】３日間培養した色素細胞は顕微鏡観察後、
培養液を除去し、0.02% EDTA (エチレンジアミン テト
ラアセテート) 、次いで0.25% トリプシンを含むダルベ
ッコのリン酸緩衝液を加え剥離した。次いで、剥離した
色素細胞に培養液 9mlを加え、1000g で５分間遠心して
得られた色素細胞の白色化の程度を肉眼により比較し
た。結果を下表に示す。The pigment cells cultured for 3 days were observed under a microscope,
The culture broth was removed, and Dulbecco's phosphate buffer containing 0.02% EDTA (ethylenediamine tetraacetate) and then 0.25% trypsin was added and stripped. Next, 9 ml of the culture solution was added to the detached pigment cells, and the pigment cells were centrifuged at 1000 g for 5 minutes, and the degree of whitening of the pigment cells was visually compared. The results are shown in the table below.
【００２０】[0020]
【表１】 以上の結果より本発明のエキスは同濃度のアルブチン、
コウジ酸より色素細胞に対する白色化効果を強く示すこ
とが認められた。[Table 1] From the above results, the extract of the present invention has the same concentration of arbutin,
It was confirmed that the whitening effect on pigment cells was stronger than that of kojic acid.
【００２１】参考例１ エンレイソウ(Trillium smallii Maxim.) 根茎の乾燥粉
末 320g を３l のメタノールで抽出した。残渣を再度２
l のメタノールで抽出し、ふたつの抽出液を合わせて減
圧濃縮し乾固した。エキス得量56g 、収率18％。Reference Example 1 320 g of dry powder of trillium (Trillium smallii Maxim.) Rhizome was extracted with 3 l of methanol. The residue again 2
It was extracted with l of methanol, and the two extracts were combined and concentrated under reduced pressure to dryness. Extract yield 56g, yield 18%.
【００２２】参考例２ エンレイソウ根茎の乾燥粉末10kgを90l のエタノールで
抽出した。残渣を再度60l のエタノールで抽出し、ふた
つの抽出液を合わせて減圧濃縮し乾固した。エキス得量
1.5kg、収率15％。Reference Example 2 10 kg of dry powder of trillium rhizome was extracted with 90 l of ethanol. The residue was extracted again with 60 l of ethanol, and the two extracts were combined and concentrated under reduced pressure to dryness. Extract yield
1.5 kg, yield 15%.
【００２３】参考例３ エンレイソウ(Trillium smallii Maxim.) 根茎の乾燥粉
末 320g を３l の１，３−ブチレングリコールで抽出し
た。残渣を再度２l の１，３−ブチレングリコールで抽
出し、ふたつの抽出液を合わせて減圧濃縮し乾固した。
エキス得量45g、収率14％。Reference Example 3 320 g of dry powder of trillium (Trillium smallii Maxim.) Rhizome was extracted with 3 l of 1,3-butylene glycol. The residue was extracted again with 2 l of 1,3-butylene glycol, and the two extracts were combined and concentrated under reduced pressure to dryness.
Extract yield 45g, yield 14%.
【００２４】参考例４ エンレイソウ(Trillium smallii Maxim.) 根茎の乾燥粉
末 320g を３l の酢酸エチルで抽出した。残渣を再度２
l の酢酸エチルで抽出し、ふたつの抽出液を合わせて減
圧濃縮し乾固した。エキス得量17g 、収率 5.3％。Reference Example 4 320 g of dry powder of trillium (Trillium smallii Maxim.) Rhizome was extracted with 3 l of ethyl acetate. The residue again 2
It was extracted with l of ethyl acetate, and the two extracts were combined and concentrated under reduced pressure to dryness. Extract yield 17g, yield 5.3%.
【００２５】参考例５ チュウリップ(Tulipa gesneriana L.)花の乾燥粉末 560
g をメタノールで抽出した。残渣を再度メタノールで抽
出し、ふたつの抽出液を合わせて減圧濃縮し乾固した。
エキス得量194g、収率35％。Reference Example 5 Dried powder of tulip (Tulipa gesneriana L.) flowers 560
g was extracted with methanol. The residue was extracted again with methanol, and the two extracts were combined and concentrated under reduced pressure to dryness.
Extract yield 194g, yield 35%.
【００２６】参考例６ ハナスゲ(Anemarrhena asphodeloides Bunge) 全草の乾
燥粉末 495g をメタノール 2.1l で抽出した。残渣を再
度メタノール 1.5l で抽出し、ふたつの抽出液を合わせ
て減圧濃縮し乾固した。エキス得量36g 、収率 7.2％。Reference Example 6 495 g of dry powder of whole plant (Anemarrhena asphodeloides Bunge) was extracted with 2.1 l of methanol. The residue was extracted again with 1.5 l of methanol, and the two extracts were combined and concentrated under reduced pressure to dryness. Extract yield 36g, yield 7.2%.
【００２７】参考例７ ジャノヒゲ(Ophiopogon japonicus Ker-Gawl.)全草の乾
燥粉末 510g をメタノール 1.9l で抽出した。残渣を再
度メタノール 1.4l で抽出し、ふたつの抽出液を合わせ
て減圧濃縮し乾固した。エキス得量36g 、収率 7.2％。Reference Example 7 510 g of dry powder of whole plant of Ophiopogon japonicus Ker-Gawl. Was extracted with 1.9 l of methanol. The residue was extracted again with 1.4 l of methanol, and the two extracts were combined and concentrated under reduced pressure to dryness. Extract yield 36g, yield 7.2%.
【００２８】参考例８ チトセラン(Sansevieria trifasciata Prain) 全草の乾
燥粉末 440g をメタノールで抽出した。残渣を再度メタ
ノールで抽出し、ふたつの抽出液を合わせて減圧濃縮し
乾固した。エキス得量28g 、収率 6.3％。Reference Example 8 440 g of dry powder of cytoseran (Sansevieria trifasciata Prain) whole plant was extracted with methanol. The residue was extracted again with methanol, and the two extracts were combined and concentrated under reduced pressure to dryness. Extract yield 28g, yield 6.3%.
【００２９】実施例１（化粧水）Example 1 (lotion)
【表２】 [Table 2]
【００３０】精製水にグリセリン、クエン酸、クエン酸
ナトリウム、水溶性プラセンタエキスを溶解する。別個
にエタノールにポリオキシエチレン硬化ヒマシ油、参考
例２の抽出エキス、メチルパラベン、香料を溶解し、前
記の精製水溶液に加えて可溶化し、濾過して化粧水を得
た。Glycerin, citric acid, sodium citrate and a water-soluble placenta extract are dissolved in purified water. Separately, polyoxyethylene hydrogenated castor oil, the extract of Reference Example 2, methylparaben, and a fragrance were separately dissolved in ethanol, added to the above-mentioned purified aqueous solution to be solubilized, and filtered to obtain a lotion.
【００３１】実施例２（化粧用油）Example 2 (cosmetic oil)
【表３】 スクワランに他の成分を均一に溶解して化粧用油を得
た。[Table 3] Other ingredients were uniformly dissolved in squalane to obtain a cosmetic oil.
【００３２】実施例３（クリーム）Example 3 (cream)
【表４】 [Table 4]
【００３３】成分（Ａ）を可熱溶解し、80℃に保持す
る。別に香料を除く成分（Ｂ）を可熱溶解して80℃に保
ち、これに前記成分（Ａ）を加え攪拌しながら冷却を行
い、香料を加え、さらに室温まで冷却してクリームを得
た。The component (A) is heat-melted and kept at 80 ° C. Separately, the component (B) excluding the fragrance was heat-melted and kept at 80 ° C., the component (A) was added thereto and cooled with stirring, the fragrance was added and further cooled to room temperature to obtain a cream.
【００３４】実施例４（乳液）Example 4 (milky lotion)
【表５】 [Table 5]
【００３５】成分（Ａ）を80℃にて加熱し、別に加温
（80℃）溶解した香料を除く成分（Ｂ）に攪拌しながら
加え、充分混合する。ついで、攪拌しながら冷却を行
い、香料を加え、さらに室温まで冷却して乳液を得た。The component (A) is heated at 80 ° C., and separately heated (80 ° C.) to the component (B) excluding the dissolved perfume while stirring and sufficiently mixed. Then, the mixture was cooled with stirring, a fragrance was added, and further cooled to room temperature to obtain an emulsion.
【００３６】実施例５（パック）Example 5 (pack)
【表６】 [Table 6]
【００３７】参考例２の抽出エキス、香料及びエタノー
ルを均一に溶解する。これを酢酸ビニル・スチレン共重
合体、ポリビニルアルコール、ソルビット、酸化チタン
およびカオリンを均一に混和したものに加える。これ
に、さらに水溶性プラセンタエキス、パラオキシ安息香
酸エチルを精製水に均一に溶解した溶液を加え、均一に
混和しパックを得た。The extract, flavor and ethanol of Reference Example 2 are uniformly dissolved. This is added to a homogeneous mixture of vinyl acetate / styrene copolymer, polyvinyl alcohol, sorbit, titanium oxide and kaolin. To this, a solution in which water-soluble placenta extract and ethyl paraoxybenzoate were uniformly dissolved in purified water was added and mixed uniformly to obtain a pack.
【００３８】実施例６（パウダー）Example 6 (powder)
【表７】 参考例２の抽出エキス、及びステアリン酸デカグリセリ
ルを加熱し、70℃に保持し、これをデキストリン及びタ
ルクの混合物に攪拌しながら徐々に加えてパウダーを得
た。[Table 7] The extract of Reference Example 2 and decaglyceryl stearate were heated and kept at 70 ° C., and this was gradually added to a mixture of dextrin and talc with stirring to obtain a powder.
【００３９】[0039]
【発明の効果】本発明美白化粧料組成物は、皮膚に適用
することにより、紫外線による皮膚の黒化若しくは色素
沈着を消失し、又は予防し、優れた美白効果を発揮す
る。The whitening cosmetic composition of the present invention, when applied to the skin, eliminates or prevents blackening or pigmentation of the skin due to ultraviolet rays, and exerts an excellent whitening effect.
フロントページの続き (72)発明者 西田 美恵子 大阪府高槻市朝日町３番１号 サンスター 株式会社内Front page continuation (72) Inventor Mieko Nishida 3-1, Asahi-cho, Takatsuki-shi, Osaka Sunstar Co., Ltd.
Claims (12)
e) の成分であって、中間極性を有する有機溶媒、一価
若しくは多価の低級アルコール、又はこれらの混合物に
可溶性を示すものを含有することを特徴とする美白化粧
料組成物。1. A lily family plant (Liliacea) as an active ingredient.
A whitening cosmetic composition comprising the component (e), which is soluble in an organic solvent having an intermediate polarity, a monohydric or polyhydric lower alcohol, or a mixture thereof.
m Linn.)に属する植物である請求項１記載の美白化粧料
組成物。2. The lily plant is a genus Trillium (Trilliu).
2. A whitening cosmetic composition according to claim 1, which is a plant belonging to m Linn.).
イソウ(Trillium smallii Maxim.) である請求項２記載
の美白化粧料組成物。3. The whitening cosmetic composition according to claim 2, wherein the plant belonging to the genus Trillium is Trillium smallii Maxim.
に属する植物である請求項１記載の美白化粧料組成物。4. The lily plant is a genus of Amana (Tulipa Linn.).
The whitening cosmetic composition according to claim 1, which is a plant belonging to
(Tulipa gesneriana L.)である請求項４記載の美白化粧
料組成物。5. A plant belonging to the genus Amana is Tulip.
(Tulipa gesneriana L.) The whitening cosmetic composition according to claim 4.
Bunge) に属する植物である請求項１記載の美白化粧料
組成物。6. The lily plant is the genus Anemarrhena.
The whitening cosmetic composition according to claim 1, which is a plant belonging to Bunge).
nemarrhena asphodeloides Bunge) である請求項６記載
の美白化粧料組成物。7. A plant belonging to the genus Anemone genus
The whitening cosmetic composition according to claim 6, which is nemarrhena asphodeloides Bunge.
n Ker-Gawl.)に属する植物である請求項１記載の美白化
粧料組成物。8. The lily plant is of the genus Ophiopogo.
n Ker-Gawl.), the whitening cosmetic composition according to claim 1.
ゲ(Ophiopogon japonicus Ker-Gawl.)である請求項８記
載の美白化粧料組成物。9. The whitening cosmetic composition according to claim 8, wherein the plant belonging to the genus Jardinium is Ophiopogon japonicus Ker-Gawl.
eria Thunb.)に属する植物である請求項１記載の美白化
粧料組成物。10. The lily family plant is of the genus Cytoceran (Sansevi).
The whitening cosmetic composition according to claim 1, which is a plant belonging to eria Thunb.).
ラン(Sansevieria trifasciata Prain) である請求項１
０記載の美白化粧料組成物。11. The plant belonging to the genus Cytocelan is cytoseran (Sansevieria trifasciata Prain).
The whitening cosmetic composition according to 0.
ン、エチルエーテル、クロロホルム、塩化メチレン、酢
酸エチル、酢酸ブチル、又はアセトンであり、一価若し
くは多価の低級アルコールが、メタノール、エタノール
又は１，３−ブチレングリコールである請求項１、請求
項２、請求項３、請求項４、請求項５、請求項６、請求
項７、請求項８、請求項９、請求項１０、又は請求項１
１記載の美白化粧料組成物。12. The organic solvent having an intermediate polarity is benzene, ethyl ether, chloroform, methylene chloride, ethyl acetate, butyl acetate, or acetone, and the monohydric or polyhydric lower alcohol is methanol, ethanol or 1, It is 3-butylene glycol, Claim 1, Claim 2, Claim 3, Claim 4, Claim 5, Claim 6, Claim 7, Claim 8, Claim 9, Claim 10, or Claim 1.
The whitening cosmetic composition according to 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5037586A JPH05345718A (en) | 1992-02-03 | 1993-02-02 | Whitening cosmetic composition |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4803392 | 1992-02-03 | ||
| JP4-48033 | 1992-02-03 | ||
| JP5037586A JPH05345718A (en) | 1992-02-03 | 1993-02-02 | Whitening cosmetic composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH05345718A true JPH05345718A (en) | 1993-12-27 |
Family
ID=26376716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5037586A Withdrawn JPH05345718A (en) | 1992-02-03 | 1993-02-02 | Whitening cosmetic composition |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH05345718A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0892056A (en) * | 1994-09-22 | 1996-04-09 | Kao Corp | Whitening cosmetic |
| WO2001070186A1 (en) * | 2000-03-23 | 2001-09-27 | Coty B.V. | Cosmetic compact or creme powder |
| JP2005170910A (en) * | 2003-12-15 | 2005-06-30 | Kuraray Co Ltd | Skin care preparation for external use |
| JPWO2004050053A1 (en) * | 2002-12-02 | 2006-03-30 | ポーラ化成工業株式会社 | Melanocyte dendrite elongation inhibitor and skin external preparation containing the same |
| JP2009256243A (en) * | 2008-04-17 | 2009-11-05 | Noevir Co Ltd | Humectant, antiaging agent, antioxidant, skin care preparation and functional oral composition |
| KR20150079246A (en) * | 2013-12-31 | 2015-07-08 | 주식회사 풀무원 | A cosmetic composition effective for skin whitening comprising multiple herbal extracts |
-
1993
- 1993-02-02 JP JP5037586A patent/JPH05345718A/en not_active Withdrawn
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0892056A (en) * | 1994-09-22 | 1996-04-09 | Kao Corp | Whitening cosmetic |
| WO2001070186A1 (en) * | 2000-03-23 | 2001-09-27 | Coty B.V. | Cosmetic compact or creme powder |
| JPWO2004050053A1 (en) * | 2002-12-02 | 2006-03-30 | ポーラ化成工業株式会社 | Melanocyte dendrite elongation inhibitor and skin external preparation containing the same |
| JP4641419B2 (en) * | 2002-12-02 | 2011-03-02 | ポーラ化成工業株式会社 | Melanocyte dendrite elongation inhibitor and skin external preparation containing the same |
| JP2005170910A (en) * | 2003-12-15 | 2005-06-30 | Kuraray Co Ltd | Skin care preparation for external use |
| JP2009256243A (en) * | 2008-04-17 | 2009-11-05 | Noevir Co Ltd | Humectant, antiaging agent, antioxidant, skin care preparation and functional oral composition |
| KR20150079246A (en) * | 2013-12-31 | 2015-07-08 | 주식회사 풀무원 | A cosmetic composition effective for skin whitening comprising multiple herbal extracts |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A300 | Withdrawal of application because of no request for examination |
Free format text: JAPANESE INTERMEDIATE CODE: A300 Effective date: 20000404 |