JPH05232073A - Electrolyte measuring device - Google Patents
Electrolyte measuring deviceInfo
- Publication number
- JPH05232073A JPH05232073A JP7237592A JP7237592A JPH05232073A JP H05232073 A JPH05232073 A JP H05232073A JP 7237592 A JP7237592 A JP 7237592A JP 7237592 A JP7237592 A JP 7237592A JP H05232073 A JPH05232073 A JP H05232073A
- Authority
- JP
- Japan
- Prior art keywords
- liquid
- temperature
- membrane electrode
- electrolyte
- measuring device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- Investigating Or Analyzing Materials Using Thermal Means (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は電解質測定装置に関し，
より詳細には，臨床検査の自動分析装置に使用される高
速処理に最適な電解質測定装置に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an electrolyte measuring device,
More specifically, the present invention relates to an electrolyte measuring device that is most suitable for high-speed processing used in an automatic analyzer for clinical tests.
【０００２】[0002]
【従来の技術】従来の電解質測定装置では，電解質溶液
の濃度を測定する場合，所定のチューブ等を用いて被検
液を導いて膜電極に接触させ，膜電極の膜面での電気化
学的平衡状態が安定するまでの一定時間の間，被検液を
静止させた後，膜電極の電位を測定して電解質溶液の濃
度を測定している。2. Description of the Related Art In a conventional electrolyte measuring apparatus, when measuring the concentration of an electrolyte solution, a test tube is used to guide a test liquid to bring it into contact with a membrane electrode, and then an electrochemical reaction on the membrane surface of the membrane electrode After allowing the test solution to stand still for a certain period of time until the equilibrium state stabilizes, the potential of the membrane electrode is measured to measure the concentration of the electrolyte solution.
【０００３】尚，このときの膜電極の出力値は被検液や
基準液の温度変化によって影響されるため，従来の電解
質測定装置では，膜電極自身或いは膜電極を含む環境を
一定の雰囲気温度に保ち，更に，ヒータや，恒温槽等の
装置を用いて被検液及び基準液の温度も予め同一の温度
に保持するようにしている。具体的には，被検液或いは
基準液のセル（収納容器）回りを３０℃〜３７℃の恒温
状態になるようにしている。Since the output value of the membrane electrode at this time is influenced by the temperature change of the test liquid or the reference liquid, in the conventional electrolyte measuring apparatus, the membrane electrode itself or the environment including the membrane electrode is kept at a constant ambient temperature. In addition, the temperature of the test liquid and the reference liquid is kept at the same temperature in advance by using a device such as a heater or a constant temperature bath. Specifically, the temperature around the cell (accommodation container) of the test liquid or the reference liquid is kept constant at 30 ° C to 37 ° C.
【０００４】[0004]
【発明が解決しようとする課題】しかしながら，従来の
電解質測定装置によれば，被検液や基準液が所定の温度
になるためには長時間を必要としていた。また，ヒータ
や，恒温槽等を用いて被検液及び基準液の温度を３０℃
〜３７℃の恒温状態に維持しているため，膜電極がダメ
ージを受け，寿命が短くなるという問題点があった。However, according to the conventional electrolyte measuring apparatus, it takes a long time for the test solution and the reference solution to reach a predetermined temperature. In addition, the temperature of the test solution and the reference solution should be 30 ℃
Since the temperature is maintained at a constant temperature of 37 ° C, the membrane electrode is damaged and the life is shortened.
【０００５】また，雰囲気温度と恒温槽の温度との差が
大きい場合には，チューブ等の流路を通過する間に被検
液や基準液の温度が変化するため，測定精度が悪くなる
という問題点もあた。Further, when the difference between the ambient temperature and the temperature of the constant temperature bath is large, the temperature of the test liquid or the reference liquid changes while passing through the flow path such as a tube, which deteriorates the measurement accuracy. There were also problems.
【０００６】また，従来の電解質測定装置では，ヒータ
を用いて，被検液及び基準液の温度を予め３０℃〜３７
℃に保持しているため，測定開始に先立って温度を一定
にするためのウォーミングアップが必要であり，測定可
能になるまでに時間がかかるという問題点もあった。Further, in the conventional electrolyte measuring device, the temperature of the test liquid and the reference liquid is set in advance at 30 ° C. to 37 ° C. by using a heater.
Since the temperature is kept at ℃, warming up is required to keep the temperature constant before starting the measurement, and there is also a problem that it takes time before measurement is possible.
【０００７】本発明は上記に鑑みてなされたものであっ
て，膜電極に与えるダメージを低減することを目的とす
る。The present invention has been made in view of the above, and an object thereof is to reduce the damage given to the membrane electrode.
【０００８】また，本発明は上記に鑑みてなされたもの
であって，雰囲気温度の影響を少なくして，精度の良い
測定が行えることを目的とする。Further, the present invention has been made in view of the above, and it is an object of the present invention to reduce the influence of ambient temperature and perform accurate measurement.
【０００９】また，本発明は上記に鑑みてなされたもの
であって，ウォーミングアップにかかる時間を省き，測
定を随時可能にすることを目的とする。Further, the present invention has been made in view of the above, and it is an object of the present invention to save time required for warming up and enable measurement at any time.
【００１０】[0010]
【課題を解決するための手段】本発明は上記の目的を達
成するために，被検液を膜電極に接触させて，被検液と
膜電極との間の電圧（電位差）によって電解質濃度を測
定する電解質測定装置において，内部に熱伝導性の高い
液を収納して，膜電極の直前に配置された温度調整槽
と，所定の収納容器内の被検液或いは基準液を温度調整
槽内の熱伝導性の高い液を通過させて膜電極へ導くため
の流路となるチューブとを備えた電解質測定装置を提供
するものである。尚，前述した熱伝導性の高い液は高絶
縁性であり，且つ，温度調整槽の温度は雰囲気温度であ
ることが望ましい。In order to achieve the above-mentioned object, the present invention brings a test solution into contact with a membrane electrode and determines the electrolyte concentration by the voltage (potential difference) between the test solution and the membrane electrode. In an electrolyte measuring device for measurement, a liquid having high thermal conductivity is housed inside, and a temperature adjusting tank placed immediately before the membrane electrode and a test liquid or a reference liquid in a predetermined housing container are placed in the temperature adjusting tank. The present invention provides an electrolyte measuring device, comprising: a tube serving as a flow path for passing a liquid having high thermal conductivity and guiding the liquid to the membrane electrode. It is desirable that the above-mentioned liquid having a high thermal conductivity has a high insulating property, and that the temperature of the temperature adjusting tank is the ambient temperature.
【００１１】[0011]
【作用】本発明の電解質測定装置は，温度調整槽の温度
を回りの雰囲気温度とし，被検液或いは基準液を温度調
整槽内の熱伝導性の高い液を潜らせて配設したチューブ
を通して一定温度にした後，膜電極に接触させて，被検
液と膜電極との間の電圧（電位差）によって電解質濃度
を測定する。In the electrolyte measuring apparatus of the present invention, the temperature of the temperature adjusting tank is set to the ambient temperature, and the test liquid or the reference liquid is passed through the tube in which the liquid having high thermal conductivity is submerged in the temperature adjusting tank. After keeping the temperature constant, the membrane electrode is brought into contact with the membrane electrode, and the electrolyte concentration is measured by the voltage (potential difference) between the test solution and the membrane electrode.
【００１２】[0012]
【実施例】以下，本発明の電解質測定装置の一実施例に
ついて，図面を参照して詳細に説明する。DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS An embodiment of the electrolyte measuring device of the present invention will be described in detail below with reference to the drawings.
【００１３】図１は，本実施例の電解質測定装置の概略
構成を示し，サンプル（被検液）をサンプリングするた
めのシッパーチューブ１０１ａと，基準液をサンプリン
グするためのシッパーチューブ１０１ｂと，熱伝導性が
高く，高絶縁性の内部液１０２ａで満たされた温度調整
槽１０２と，シッパーチューブ１０１ａ，１０１ｂを介
して導かれたサンプル或いは基準液の何れか一方を後述
する膜電極側へ導くための電磁弁１０３と，サンプルの
各電解質（Cl，Na，Ｋ）の電位を測定するためのイオン
選択性膜電極１０４ａ，１０４ｂ，１０４ｃと，各膜電
極１０４ａ〜１０４ｄの測定電圧を入力してサンプルの
電解質濃度を演算するＣＰＵ１０５と，測定結果（電解
質濃度）を出力するためのプリンター１０６及び表示器
１０７とを備えている。FIG. 1 shows a schematic structure of an electrolyte measuring apparatus according to this embodiment, which includes a sipper tube 101a for sampling a sample (test liquid), a sipper tube 101b for sampling a reference liquid, and heat conduction. For introducing the temperature control tank 102, which is filled with the highly insulative internal liquid 102a, and the sample or the reference liquid introduced through the sipper tubes 101a and 101b, to the membrane electrode side described later. The electromagnetic valve 103, the ion-selective membrane electrodes 104a, 104b, 104c for measuring the potential of each electrolyte (Cl, Na, K) of the sample, and the measurement voltage of each of the membrane electrodes 104a to 104d are input to input the sample. A CPU 105 for calculating an electrolyte concentration, a printer 106 for outputting a measurement result (electrolyte concentration) and a display 107 are provided. It
【００１４】ここで，イオン選択性膜電極１０４ａは，
電解質としてCl（塩素）を選択的に測定するものであ
り，本実施例では超積層固体化分子配向性膜（ＭＯ膜）
電極を使用する。また，イオン選択性膜電極１０４ｂ
は，電解質としてNa（ナトリウム）を選択的に測定する
ものであり，本実施例ではクラウンエーテル膜電極を使
用する。また，イオン選択性膜電極１０４ｃは，電解質
としてＫ（カリウム）を選択的に測定するものであり，
本実施例ではクラウンエーテル膜電極を使用する。Here, the ion selective membrane electrode 104a is
Cl (chlorine) is selectively measured as an electrolyte, and in this embodiment, a super laminated solidified molecular orientation film (MO film) is used.
Use electrodes. Also, the ion-selective membrane electrode 104b
Is to selectively measure Na (sodium) as an electrolyte, and a crown ether membrane electrode is used in this embodiment. The ion selective membrane electrode 104c selectively measures K (potassium) as an electrolyte,
In this embodiment, a crown ether membrane electrode is used.
【００１５】また，シッパーチューブ１０１ａ，１０１
ｂは，サンプル及び基準液が温度調整槽１０２の内部液
１０２ａと効率良く熱交換を行って一定温度になるよう
に，図示の如く，螺旋形状となって内部液１０２ａを通
過する。Further, the sipper tubes 101a, 101
The sample b and the reference solution pass through the internal solution 102a in a spiral shape as shown in the figure so that the sample and the reference solution efficiently exchange heat with the internal solution 102a of the temperature adjusting tank 102 and have a constant temperature.
【００１６】温度調整槽１０２の内部液１０２ａを熱伝
導性の高い液とするのは，サンプル或いは基準液を収納
したセル（図示せず）回りの雰囲気温度と，温度調整槽
１０２内の温度とが略一定となるようにするためであ
る。また，高絶縁性液とするのは，液体の移動による静
電気等のノイズを防止するためである。The internal liquid 102a of the temperature adjusting tank 102 has a high thermal conductivity because of the ambient temperature around the cell (not shown) containing the sample or reference liquid and the temperature inside the temperature adjusting tank 102. This is so that is substantially constant. Further, the high insulating liquid is used to prevent noise such as static electricity due to movement of the liquid.
【００１７】尚，図示を省略するが，サンプル及び基準
液は，それぞれ専用のセルに収納された状態で雰囲気温
度中に置かれている。このセル内のサンプル或いは基準
液を所定のポンプで吸引することにより，各膜電極１０
４ａ〜１０４ｄの方向へ運ぶ構成である。Although not shown in the drawing, the sample and the reference solution are stored in dedicated cells and are placed at ambient temperature. By sucking the sample or reference solution in this cell with a predetermined pump, each membrane electrode 10
4a to 104d.
【００１８】以上の構成において，その動作を説明す
る。先ず，ＣＰＵ１０５は，サンプルの吸引が行えるよ
うに電磁弁１０３を切り替えて，吸引ポンプ（図示せ
ず）を駆動してサンプルの吸引を開始する。サンプルは
流路であるシッパーチューブ１０１ａに導かれて，温度
調整槽１０２内を通過する。The operation of the above configuration will be described. First, the CPU 105 switches the solenoid valve 103 so that the sample can be sucked, and drives a suction pump (not shown) to start sucking the sample. The sample is guided to the sipper tube 101a, which is a channel, and passes through the temperature adjusting tank 102.
【００１９】このとき，温度調整槽１０２内の温度は，
熱伝導性の高い内部液１０２ａによって雰囲気温度と同
一の温度となっている。サンプルはシッパーチューブ１
０１ａの壁を介して内部液１０２ａと熱交換を行いなが
ら温度調整槽１０２内を移動し，一定温度となって状態
で各膜電極１０４ａ〜１０４ｄに接触する。At this time, the temperature in the temperature adjusting tank 102 is
Due to the internal liquid 102a having high thermal conductivity, the temperature is the same as the ambient temperature. Sample is sipper tube 1
It moves in the temperature adjusting tank 102 while exchanging heat with the internal liquid 102a through the wall of 01a, and comes into contact with each of the membrane electrodes 104a to 104d at a constant temperature.
【００２０】膜電極１０４ａ，１０４ｂ，１０４ｃ，及
び，比較膜電極１０４ｄと接触した後，サンプルは吸引
ポンプを通過して排液として排出される。この時，膜電
極１０４ａ，１０４ｂ，１０４ｃはそれぞれ該当する電
解質の電圧を測定して信号（測定電圧）を出力する。Ｃ
ＰＵ１０５は，膜電極１０４ａ，１０４ｂ，１０４ｃか
ら出力された測定電圧を入力し，サンプルの電解質濃度
を演算して求め，測定結果（電解質濃度）をプリンター
１０６及び表示器１０７を介して出力する。After contact with the membrane electrodes 104a, 104b, 104c and the comparative membrane electrode 104d, the sample passes through the suction pump and is discharged as drainage. At this time, the membrane electrodes 104a, 104b and 104c respectively measure the voltage of the corresponding electrolyte and output a signal (measurement voltage). C
The PU 105 inputs the measurement voltage output from the membrane electrodes 104a, 104b, 104c, calculates the electrolyte concentration of the sample, obtains it, and outputs the measurement result (electrolyte concentration) via the printer 106 and the display 107.
【００２１】一方，基準液の測定を行う場合には，電磁
弁１０３を切り替えて，同様の処理を行う。On the other hand, when measuring the reference liquid, the solenoid valve 103 is switched and the same processing is performed.
【００２２】前述したように本実施例では，ヒータを使
用せずにサンプルの温度と基準液の温度を一定にするこ
とができ，装置の構成を簡単にすることができる。As described above, in this embodiment, the temperature of the sample and the temperature of the reference liquid can be made constant without using a heater, and the structure of the device can be simplified.
【００２３】また，温度調整槽１０２を用いて，サンプ
ル及び基準液の温度を回りの雰囲気温度に調整して，各
膜電極１０４ａ〜１０４ｄと接触させるため，膜電極の
受けるダメージが少なくなり，寿命を伸ばすことができ
る。Further, since the temperature of the sample and the reference solution is adjusted to the ambient temperature using the temperature adjusting tank 102 and brought into contact with each of the membrane electrodes 104a to 104d, the damage to the membrane electrodes is reduced and the life is shortened. Can be extended.
【００２４】また，電解質測定装置全体を通して，雰囲
気温度を調整温度値（即ち，測定温度値）としているの
で，雰囲気温度の影響，換言すれば，雰囲気温度と測定
温度との差による測定精度の低下を防ぐことができ，更
に，ウォーミングアップの時間を必要とせずに随時処理
を開始することができる。Further, since the ambient temperature is used as the adjusted temperature value (that is, the measurement temperature value) throughout the electrolyte measuring apparatus, the influence of the ambient temperature, in other words, the decrease in the measurement accuracy due to the difference between the ambient temperature and the measurement temperature. In addition, the processing can be started at any time without requiring the warm-up time.
【００２５】[0025]
【発明の効果】以上説明したように本発明の電解質測定
装置は，被検液を膜電極に接触させて，被検液と膜電極
との間の電圧（電位差）によって電解質濃度を測定する
電解質測定装置において，内部に熱伝導性の高い液を収
納して，膜電極の直前に配置された温度調整槽と，所定
の収納容器内の被検液或いは基準液を温度調整槽内の熱
伝導性の高い液を通過させて膜電極へ導くための流路と
なるチューブとを備えたため，膜電極に与えるダメージ
を低減して，膜電極の寿命を伸ばすことができる。ま
た，雰囲気温度の影響を少なくして，精度の良い測定を
行うことができる。また，ウォーミングアップにかかる
時間を省き，測定を随時可能にすることができる。As described above, the electrolyte measuring apparatus of the present invention is an electrolyte for measuring the electrolyte concentration by bringing the test liquid into contact with the membrane electrode and measuring the voltage (potential difference) between the test liquid and the membrane electrode. In the measuring device, a liquid with high thermal conductivity is stored inside, and the temperature control tank placed immediately before the membrane electrode and the test liquid or reference liquid in a predetermined storage container are transferred to the heat conduction inside the temperature control tank. Since it is provided with a tube that serves as a flow path for passing a liquid having a high property and guiding it to the membrane electrode, damage to the membrane electrode can be reduced and the life of the membrane electrode can be extended. In addition, the influence of the ambient temperature can be reduced and accurate measurement can be performed. In addition, the time required for warming up can be saved and measurement can be performed at any time.
【図１】本発明の電解質測定装置の概略構成を示す説明
図である。FIG. 1 is an explanatory diagram showing a schematic configuration of an electrolyte measuring device of the present invention.
１０１ａ １０１ｂ シッパーチューブ １０２ 温度調整槽 １０２ａ 内部液 １０３ 電磁弁 １０４ａ １０４ｂ １０４ｃ イオン選択性膜電極 １０４ｄ 比較膜電極 １０３ 電磁弁 １０５ ＣＰＵ 101a 101b Shipper tube 102 Temperature control tank 102a Internal liquid 103 Solenoid valve 104a 104b 104c Ion-selective membrane electrode 104d Comparative membrane electrode 103 Solenoid valve 105 CPU
Claims (2)
膜電極との間の電圧（電位差）によって電解質濃度を測
定する電解質測定装置において，内部に熱伝導性の高い
液を収納して，前記膜電極の直前に配置された温度調整
槽と，所定の収納容器内の被検液或いは基準液を前記温
度調整槽内の熱伝導性の高い液を通過させて前記膜電極
へ導くための流路となるチューブとを備えたことを特徴
とする電解質測定装置。1. An electrolyte measuring apparatus for contacting a test liquid with a membrane electrode to measure an electrolyte concentration by a voltage (potential difference) between the test liquid and the membrane electrode, wherein a liquid having high thermal conductivity is provided inside. The membrane electrode which is housed and placed immediately before the membrane electrode, and the test liquid or reference liquid in a predetermined container is passed through the liquid having high thermal conductivity in the temperature regulation tank. An electrolyte measuring device, comprising: a tube serving as a flow path for leading to the electrolyte.
り，且つ，前記温度調整槽の温度は雰囲気温度であるこ
とを特徴とする請求項１記載の電解質測定装置。2. The electrolyte measuring apparatus according to claim 1, wherein the liquid having a high thermal conductivity has a high insulating property, and the temperature of the temperature adjusting tank is an ambient temperature.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP07237592A JP3274489B2 (en) | 1992-02-21 | 1992-02-21 | Electrolyte measuring device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP07237592A JP3274489B2 (en) | 1992-02-21 | 1992-02-21 | Electrolyte measuring device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH05232073A true JPH05232073A (en) | 1993-09-07 |
| JP3274489B2 JP3274489B2 (en) | 2002-04-15 |
Family
ID=13487494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP07237592A Expired - Fee Related JP3274489B2 (en) | 1992-02-21 | 1992-02-21 | Electrolyte measuring device |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3274489B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007057367A (en) * | 2005-08-24 | 2007-03-08 | Hitachi High-Technologies Corp | Method and device for measuring electrolyte |
-
1992
- 1992-02-21 JP JP07237592A patent/JP3274489B2/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007057367A (en) * | 2005-08-24 | 2007-03-08 | Hitachi High-Technologies Corp | Method and device for measuring electrolyte |
| JP4620551B2 (en) * | 2005-08-24 | 2011-01-26 | 株式会社日立ハイテクノロジーズ | Electrolyte measuring device |
Also Published As
| Publication number | Publication date |
|---|---|
| JP3274489B2 (en) | 2002-04-15 |
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