JPH0481439B2 - - Google Patents
Info
- Publication number
- JPH0481439B2 JPH0481439B2 JP60234236A JP23423685A JPH0481439B2 JP H0481439 B2 JPH0481439 B2 JP H0481439B2 JP 60234236 A JP60234236 A JP 60234236A JP 23423685 A JP23423685 A JP 23423685A JP H0481439 B2 JPH0481439 B2 JP H0481439B2
- Authority
- JP
- Japan
- Prior art keywords
- layer
- reaction
- analytical element
- coenzyme
- electron
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 46
- 239000005515 coenzyme Substances 0.000 claims description 46
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- 235000005152 nicotinamide Nutrition 0.000 claims description 23
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- 239000000758 substrate Substances 0.000 claims description 23
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims description 22
- 102000004190 Enzymes Human genes 0.000 claims description 21
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- 239000003381 stabilizer Substances 0.000 claims description 17
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- 239000002253 acid Substances 0.000 claims description 10
- 238000006911 enzymatic reaction Methods 0.000 claims description 8
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 5
- 230000002378 acidificating effect Effects 0.000 claims description 4
- 150000001413 amino acids Chemical class 0.000 claims description 4
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- XJLXINKUBYWONI-DQQFMEOOSA-N [[(2r,3r,4r,5r)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2s,3r,4s,5s)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate Chemical compound NC(=O)C1=CC=C[N+]([C@@H]2[C@H]([C@@H](O)[C@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](OP(O)(O)=O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 XJLXINKUBYWONI-DQQFMEOOSA-N 0.000 description 5
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
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- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- GKQWYZBANWAFMQ-UHFFFAOYSA-M lithium;2-hydroxypropanoate Chemical compound [Li+].CC(O)C([O-])=O GKQWYZBANWAFMQ-UHFFFAOYSA-M 0.000 description 4
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- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 3
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- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 2
- JEOLGCWRLRXABW-UHFFFAOYSA-N 2,5-diphenyl-2h-tetrazol-2-ium;chloride Chemical compound [Cl-].C1=CC=CC=C1C1=[NH+]N(C=2C=CC=CC=2)N=N1 JEOLGCWRLRXABW-UHFFFAOYSA-N 0.000 description 2
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- 102100036475 Alanine aminotransferase 1 Human genes 0.000 description 2
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- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
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- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 2
- 108010018962 Glucosephosphate Dehydrogenase Proteins 0.000 description 2
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 2
- DRBBFCLWYRJSJZ-UHFFFAOYSA-N N-phosphocreatine Chemical compound OC(=O)CN(C)C(=N)NP(O)(O)=O DRBBFCLWYRJSJZ-UHFFFAOYSA-N 0.000 description 2
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- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 2
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 2
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- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 description 2
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- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
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- MASUWVVNWALEEM-UHFFFAOYSA-M 1-methoxy-5-methylphenazin-5-ium;methyl sulfate Chemical compound COS([O-])(=O)=O.C1=CC=C2N=C3C(OC)=CC=CC3=[N+](C)C2=C1 MASUWVVNWALEEM-UHFFFAOYSA-M 0.000 description 1
- VONNHDXCCQVFQI-UHFFFAOYSA-N 1-methylphenazin-10-ium;methyl sulfate Chemical compound COS([O-])(=O)=O.C1=CC=C2N=C3C(C)=CC=CC3=[NH+]C2=C1 VONNHDXCCQVFQI-UHFFFAOYSA-N 0.000 description 1
- YZIXDSVRVOZUAZ-UHFFFAOYSA-N 2-(1,2-dihydrotetrazol-1-ium-3-yl)-4,5-dimethyl-1,3-thiazole;bromide Chemical compound [Br-].S1C(C)=C(C)N=C1N1N=C[NH2+]N1 YZIXDSVRVOZUAZ-UHFFFAOYSA-N 0.000 description 1
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- 239000002356 single layer Substances 0.000 description 1
- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 108010085346 steroid delta-isomerase Proteins 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000009816 wet lamination Methods 0.000 description 1
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23423685A JPS6293662A (ja) | 1985-10-18 | 1985-10-18 | 酸化型補酵素を含有する乾式分析要素 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23423685A JPS6293662A (ja) | 1985-10-18 | 1985-10-18 | 酸化型補酵素を含有する乾式分析要素 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6293662A JPS6293662A (ja) | 1987-04-30 |
JPH0481439B2 true JPH0481439B2 (de) | 1992-12-24 |
Family
ID=16967821
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP23423685A Granted JPS6293662A (ja) | 1985-10-18 | 1985-10-18 | 酸化型補酵素を含有する乾式分析要素 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6293662A (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4986281B2 (ja) * | 2004-10-05 | 2012-07-25 | 旭化成ファーマ株式会社 | 補酵素の安定化方法およびその組成物 |
JP6160094B2 (ja) * | 2013-01-29 | 2017-07-12 | 東洋紡株式会社 | ジアホラーゼ組成物 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5988097A (ja) * | 1982-11-12 | 1984-05-21 | Konishiroku Photo Ind Co Ltd | 分析素子 |
-
1985
- 1985-10-18 JP JP23423685A patent/JPS6293662A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6293662A (ja) | 1987-04-30 |
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Date | Code | Title | Description |
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LAPS | Cancellation because of no payment of annual fees |