JPH04146765A - Catheter - Google Patents
CatheterInfo
- Publication number
- JPH04146765A JPH04146765A JP2271488A JP27148890A JPH04146765A JP H04146765 A JPH04146765 A JP H04146765A JP 2271488 A JP2271488 A JP 2271488A JP 27148890 A JP27148890 A JP 27148890A JP H04146765 A JPH04146765 A JP H04146765A
- Authority
- JP
- Japan
- Prior art keywords
- catheter
- metals
- rubber
- electroless plating
- human body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910052751 metal Inorganic materials 0.000 claims abstract description 36
- 239000002184 metal Substances 0.000 claims abstract description 35
- 238000007772 electroless plating Methods 0.000 claims abstract description 19
- 230000001954 sterilising effect Effects 0.000 claims abstract description 18
- 238000011282 treatment Methods 0.000 claims abstract description 12
- 230000004913 activation Effects 0.000 claims abstract description 6
- 230000000844 anti-bacterial effect Effects 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 3
- 229910052802 copper Inorganic materials 0.000 abstract description 13
- 208000015181 infectious disease Diseases 0.000 abstract description 7
- 229910052759 nickel Inorganic materials 0.000 abstract description 7
- 238000007747 plating Methods 0.000 abstract description 7
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 6
- 239000007788 liquid Substances 0.000 abstract description 4
- 239000003054 catalyst Substances 0.000 abstract description 2
- 229910021645 metal ion Inorganic materials 0.000 abstract description 2
- 229910052709 silver Inorganic materials 0.000 abstract description 2
- 230000000638 stimulation Effects 0.000 abstract description 2
- 150000002739 metals Chemical class 0.000 abstract 6
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 230000003405 preventing effect Effects 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 239000010949 copper Substances 0.000 description 16
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 12
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Substances [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 12
- 238000001994 activation Methods 0.000 description 5
- 239000000853 adhesive Substances 0.000 description 5
- 230000001070 adhesive effect Effects 0.000 description 5
- 239000012530 fluid Substances 0.000 description 5
- 239000004809 Teflon Substances 0.000 description 4
- 229920006362 Teflon® Polymers 0.000 description 4
- 239000010931 gold Substances 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000003513 alkali Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 210000003708 urethra Anatomy 0.000 description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000000873 masking effect Effects 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- 230000002522 swelling effect Effects 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 206010046543 Urinary incontinence Diseases 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 201000003146 cystitis Diseases 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000005053 encephalomalacia Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000010944 silver (metal) Substances 0.000 description 1
- 210000000278 spinal cord Anatomy 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は体腔内に溜まった液体を排出したり、逆に液体
を体腔内に注入したりする医療用のカテーテル本体、特
に、尿道を経て膀胱に挿入する尿管カテーテル本体の壁
面に殺菌作用或いは滅菌作用を有する金属の層を形成し
てなるカテーテルに関するものである。[Detailed Description of the Invention] [Field of Industrial Application] The present invention relates to a medical catheter body for draining fluid accumulated in a body cavity or conversely injecting a fluid into a body cavity, particularly for a catheter body for discharging fluid accumulated in a body cavity or injecting a fluid into a body cavity through the urethra. The present invention relates to a catheter formed by forming a metal layer having a bactericidal or sterilizing effect on the wall surface of a ureteral catheter body inserted into the bladder.
脳を髄疾患、例えば脳溢血、脳軟化症或いはを髄損傷等
では、しばしば排尿困難、尿失禁等の症状を伴うため、
尿管カテーテルを膀胱に挿入し、留置して排尿を行わせ
ている。また、手術後の患者には排尿の補助だけでなく
体腔内に溜まった液体や膿等を排出するために各種のカ
テーテルが使用され、これらのカテーテルはその必要性
から体腔内に留置して使用されることが多い。Diseases that affect the brain, such as cerebral hemorrhage, encephalomalacia, or spinal cord damage, are often accompanied by symptoms such as difficulty urinating and urinary incontinence.
A ureteral catheter is inserted into the bladder and left in place to allow urination. In addition, various catheters are used for patients after surgery, not only to assist with urination, but also to drain fluids and pus accumulated in the body cavity. It is often done.
カテーテル本体は、従来生ゴム等のゴムを主原料として
管状に成形されて後、人体への刺激を和らげるためにテ
フロン等の樹脂をコーティングしている。このため、工
程が増えるとともに製造コストを大幅に上昇させていた
。Conventionally, the catheter body is formed into a tubular shape using rubber such as raw rubber as the main raw material, and then coated with a resin such as Teflon to reduce irritation to the human body. This increases the number of steps and significantly increases manufacturing costs.
また、カテーテルを体腔内に留置したときに問題となる
のが細菌による感染症である。特に尿管カテーテルでは
比較的長時間尿道に留置しておくため、カテーテルを通
じて肛門や性器等に付着している細菌がしばしば膀胱内
に侵入して膀胱炎を誘発させる原因をつくっている。特
に、女性の場合には男性と比較して尿道が太く、かつ短
くて直線的であるため、この細菌による感染が非常に多
い。この細菌の膀胱内侵入を防止するために従来はカテ
ーテルの管状体に殺菌作用或いは滅菌作用のある金属製
リングまたはコイルを被着させたりする提案がなされて
いる（特公昭５４−１４８７６号参照）。Furthermore, when a catheter is placed in a body cavity, bacterial infection becomes a problem. In particular, since ureteral catheters are left in the urethra for a relatively long period of time, bacteria adhering to the anus, genitals, etc., often enter the bladder through the catheter, causing cystitis. In particular, women's urethra is thicker, shorter, and straighter than men's, so infections caused by this bacteria are very common. In order to prevent these bacteria from entering the bladder, a proposal has been made to cover the tubular body of the catheter with a metal ring or coil that has a bactericidal or sterilizing effect (see Japanese Patent Publication No. 14876/1987). .
しかしながら、前記の金属リングやコイルを被着する方
法では金属リング等が太いため、カテーテルの管状体部
分の太さが太（なって患者への挿入に際し苦痛を増加さ
せることとなり、加えてカテーテルの管状体部分の所定
位置に金属リング等を固定しておくことが非常に困難で
あった。However, in the above-mentioned method of attaching a metal ring or coil, the metal ring, etc. is thick, so the tubular body of the catheter becomes thick (which increases the pain when inserting it into the patient. It is very difficult to fix a metal ring or the like in a predetermined position on the tubular body portion.
本発明は上記のような従来のカテーテルの問題点を解消
し、患者に苦痛を与えることなく、しかも感染予防の効
果が長期間保持されるカテーテルを極めて安価に提供す
ることにある。The present invention solves the problems of conventional catheters as described above, and provides an extremely inexpensive catheter that does not cause pain to the patient and maintains its infection prevention effect for a long period of time.
前記目的を達成するために、本発明は
（１）ゴムからなるカテーテル本体の少なくとも人体の
体腔内に挿入される部分全体をアクチベーション処理し
て後無電解メッキ処理してカテーテル本体に殺菌作用或
いは滅菌作用を有する金属層を形成してなることを特徴
とし、
（２）ゴムからなるカテーテル本体の少なくとも人体の
体腔内に挿入される部分全体をアルカリ性アルコール水
溶液で表面処理し、次いでアクチベーション処理を施し
て後無電解メッキ処理してカテーテル本体に殺菌作用或
いは滅菌作用を有する金属層を形成してなることを特徴
とし、
（３）更に、前記カテーテルに形成した無電解メッキ処
理金属層に３０〜１５０℃の熱処理工程を施してなるこ
とを特徴とする、
カテーテルに関するものである。In order to achieve the above object, the present invention provides (1) activation treatment of at least the entire portion of the catheter body made of rubber to be inserted into the body cavity of the human body, and then electroless plating treatment to impart sterilization or sterilization to the catheter body; (2) At least the entire portion of the catheter body made of rubber to be inserted into the body cavity of the human body is surface-treated with an aqueous alkaline alcohol solution, and then subjected to an activation treatment. A metal layer having a bactericidal or sterilizing effect is formed on the catheter body by electroless plating, and (3) the electroless plating metal layer formed on the catheter is heated at 30 to 150°C. The present invention relates to a catheter characterized in that it has been subjected to a heat treatment process.
本発明は、人体に刺激を与えるに裸の状態では使用でき
ないゴム製カテーテル本体の管状体の少なくとも体腔内
に挿入される部分に無電解メッキ処理により殺菌作用或
いは滅菌作用を有する金属層を設け、該金属層により体
内に挿入した時の人体への刺激を和らげて体腔内を損傷
することなく、しかも、カテーテルの管状体部分の太さ
が、従来のテフロンコートしたものよりむしろ細くする
ことが可能であり、（管内壁に被着した場合でも管の内
径を狭めることもなり）、更に、無電解メッキ処理後直
ちに熱処理して金属層をカテーテル本体に浸透させるこ
とで金属が容易に脱落することなく、長期間にわたって
金属イオンの放出が可能となる。従って本発明カテーテ
ルは市販のカテーテルと太さが殆ど変わらず、むしろ細
くなっているので、患者に挿入する際該患者に苦痛を与
えることな（、しかも長期間にわたり体腔内にカテーテ
ルを留置しても感染症を併発することがない。The present invention provides a metal layer having a bactericidal or sterilizing effect by electroless plating on at least the part of the tubular body of the rubber catheter body which cannot be used in a naked state because it causes irritation to the human body, and which is inserted into the body cavity. The metal layer reduces the stimulation to the human body when inserted into the body and does not damage the body cavity, and the thickness of the tubular body of the catheter can be made thinner than that of conventional Teflon-coated catheters. (Even if it adheres to the inner wall of the tube, the inner diameter of the tube may be narrowed.) Furthermore, if the metal layer is heat-treated immediately after electroless plating to penetrate the catheter body, the metal will easily fall off. metal ions can be released over a long period of time. Therefore, the catheter of the present invention has almost the same thickness as a commercially available catheter, and is actually thinner, so that it does not cause pain to the patient when inserted into the patient (in addition, the catheter can be left in the body cavity for a long period of time). There are no complications with infection.
更に、ゴム本体の表面をテフロン加工しないので安価に
提供しうる。Furthermore, since the surface of the rubber body is not treated with Teflon, it can be provided at low cost.
次に、本発明の詳細な説明する。Next, the present invention will be explained in detail.
ゴムからなるカテーテル本体にメッキ処理に必要な部分
を残してマスキングして後、アクチベーション処理によ
り無電解メッキ処理時の触媒となる例えばＰｄを吸着さ
せ、該Ｐｄを吸着させたカテーテル本体を無電解メッキ
液に浸漬してＰｄを核として金属を析出させ殺菌作用或
いは滅菌作用のある金属、例えばＣｕ、Ｎｉ、Ａｇ等を
形成する。無電解メッキ処理で形成する金属種としては
上記の他Ａｕ等殺菌作用或いは滅菌作用を有し人体に刺
激を与えない金属であれば特に限定はしない。なお、Ａ
ｕはＣｕ等の層を形成後にＡｕで置換することにより容
易にメンキすることができる。After masking the catheter body made of rubber, leaving the parts necessary for plating, an activation process is performed to adsorb, for example, Pd, which becomes a catalyst during electroless plating, and the catheter body with the Pd adsorbed is subjected to electroless plating. It is immersed in a liquid to precipitate a metal using Pd as a nucleus, thereby forming a metal having a bactericidal or sterilizing effect, such as Cu, Ni, Ag, etc. The metal species formed by electroless plating is not particularly limited as long as it has a bactericidal or sterilizing effect, such as Au, and does not cause irritation to the human body. In addition, A
u can be easily removed by forming a layer of Cu or the like and then replacing it with Au.
このようにして無電解メッキ処理で形成される金属層の
厚さは０．２μｍ〜０．６μｍ程度である。The thickness of the metal layer thus formed by electroless plating is approximately 0.2 μm to 0.6 μm.
ゴムの種類によっては直接アクチベーション処理を行っ
ても上手く無電解メッキができないことがある。このよ
うな時には、先ず、カテーテル本体を、アルカリ（例え
ばＮａＯＨ，ＫＯＨ）を１規定以上１０規定以下と、５
ｖ０１％以上５０ｖｏ１％以下のアルコールを含み残部
が水よりなるカテーテル表面処理液に浸漬してカテーテ
ル本体の壁面を膨潤させ、カテーテルを構成するゴムの
分子間隔を拡大するとともに親水基を導入する。Depending on the type of rubber, electroless plating may not be successful even if direct activation treatment is performed. In such a case, first, soak the catheter body in an alkali solution (e.g. NaOH, KOH) of 1 N or more and 10 N or less, and 5
The wall surface of the catheter body is swollen by immersing it in a catheter surface treatment liquid containing 01% to 50% alcohol and the remainder water, thereby expanding the molecular spacing of the rubber constituting the catheter and introducing hydrophilic groups.
ここでアルカリとアルコールの濃度を限定したのはアル
カリまたはアルコールの何れの成分が少なくてもゴムの
膨潤作用が弱過ぎ、また逆に、両成分が多過ぎるとゴム
の膨潤作用が強過ぎてゴム全体を劣化してしまう虞があ
るからである。The reason for limiting the concentrations of alkali and alcohol here is that if either the alkali or alcohol component is small, the rubber swelling effect will be too weak, and conversely, if both components are too large, the rubber swelling effect will be too strong, causing the rubber to become too weak. This is because there is a risk that the entire structure may deteriorate.
次いでアクチベーション処理、無電解メッキ処理を施し
て殺菌作用或いは滅菌作用のある金属をカテーテル本体
の壁面に形成する。Next, activation treatment and electroless plating treatment are performed to form a metal with a bactericidal or sterilizing effect on the wall surface of the catheter body.
なお、無電解メッキ処理で形成した金属層の接着力が弱
い場合には３０〜１５０℃で１０〜１８０分の熱処理を
施すことにより金属がゴム表面に浸透し脱落することが
なくなる。熱処理にようする温度と時間はカテーテル本
体を構成するゴムの種類ヤカテーテル表面に形成される
金属の種類によって変化するので、これらの組合せによ
り実験的に決定する必要がある。If the adhesive strength of the metal layer formed by electroless plating is weak, heat treatment at 30 to 150° C. for 10 to 180 minutes will prevent the metal from penetrating the rubber surface and falling off. The temperature and time for heat treatment vary depending on the type of rubber constituting the catheter body and the type of metal formed on the surface of the catheter, and therefore must be determined experimentally based on a combination of these.
なお、カテーテル本体の先端には管内部と連通ずる孔が
設けられているので、この孔をマスキングすることなく
無電解メッキを施せば、カテーテル本体の内壁にも金属
層を形成しうろことは勿論である。Note that the tip of the catheter body has a hole that communicates with the inside of the tube, so if electroless plating is applied without masking this hole, a metal layer will be formed on the inner wall of the catheter body as well. It is.
〔実施例１〕
生ゴムからなるカテーテル本体をアクチベータ−４４４
（メルテックス社製）でアクチベーションし、表面に活
性なＰｄを吸着させた。次いでノビガントＨＣ（日本シ
ェーリング社製）に浸漬して無電解Ｃｕメッキを施しカ
テーテル本体の表面に約０．２μｍの銅層を形成した。[Example 1] A catheter body made of raw rubber was used as an activator-444.
(manufactured by Meltex) to adsorb active Pd on the surface. Next, it was immersed in Novigant HC (manufactured by Nippon Schering Co., Ltd.) to perform electroless Cu plating to form a copper layer of about 0.2 μm on the surface of the catheter body.
この状態でも銅層はカテーテル表面に剥がれることなく
被着しているが、更に接着強度を上げるために８０℃の
エアバス中に５０分保持し銅層をゴム内に浸透させて銅
層を表面に有するカテーテルを製造した。Even in this state, the copper layer adheres to the surface of the catheter without peeling off, but in order to further increase the adhesive strength, the copper layer is kept in an air bath at 80°C for 50 minutes to allow the copper layer to penetrate into the rubber and coat the surface of the catheter. A catheter having the following was manufactured.
ゴム表面に被着した銅は均一な膜状（微視的には銅粉が
均一に被着）となっており、人体に挿入しても人体を刺
激し、体腔内を損傷することはなかった。The copper deposited on the rubber surface is in the form of a uniform film (microscopically, the copper powder is uniformly deposited), so even if it is inserted into the human body, it will not irritate the human body or damage the inside of the body cavity. Ta.
〔実施例２〕
生ゴムからなるカテーテル本体を表１に示す組成のカテ
ーテル表面処理液に３０℃で３０秒浸漬し、ゴム表面を
膨潤させた後、アクチベータ−４４４（メルテックス社
製）でアクチベーションし、表面に活性なＰｄを吸着さ
せた。次いでノビガントＨＣ（日本シェーリング社製）
に浸漬して無電解Ｃｕメッキを施しカテーテル本体の表
面に約０．２μｍの銅層を形成した。この状態でも銅層
はカテーテル表面に剥がれることなく被着しているが、
更に接着強度を上げるために８０℃のエアバス中に５０
分保持し銅層を樹脂内に浸透させて銅層を表面に有する
カテーテルを製造した。[Example 2] A catheter body made of raw rubber was immersed in a catheter surface treatment liquid having the composition shown in Table 1 at 30°C for 30 seconds to swell the rubber surface, and then activated with Activator-444 (manufactured by Meltex). , active Pd was adsorbed on the surface. Next, Novigant HC (manufactured by Nippon Schering Co., Ltd.)
The catheter body was immersed in electroless Cu plating to form a copper layer of approximately 0.2 μm on the surface of the catheter body. Even in this state, the copper layer adheres to the catheter surface without peeling off.
In order to further increase the adhesive strength, the
A catheter having a copper layer on the surface was manufactured by infiltrating the copper layer into the resin.
表１
〔実施例３〕
生ゴムからなるカテーテル本体をアクチベータ−４４４
（メルテックス社製）でアクチベーションし、表面に活
性なＰｄを吸着させた。次いでＢＥＬ−８０１（村上工
業製）に浸漬して無電解Ｎｉメッキを施しカテーテル本
体の表面に約０．６μｍのニッケル層を形成した。この
状態でもニッケル層はカテーテル表面に剥がれることな
く被着しているが、更に接着強度を上げるために８０℃
のエアバス中に６０分保持しニッケル層をゴム内に浸透
させてニッケル層を表面に有するカテーテルを製造した
。これらの処理でカテーテル本体の表面にニッケル層が
均一に形成された。このカテーテルを人体に挿入しても
人体を刺激し、体腔内を損傷することはなかった。Table 1 [Example 3] Activator-444 catheter body made of raw rubber
(manufactured by Meltex) to adsorb active Pd on the surface. Next, it was immersed in BEL-801 (manufactured by Murakami Industries) to perform electroless Ni plating to form a nickel layer of about 0.6 μm on the surface of the catheter body. Even in this state, the nickel layer adheres to the catheter surface without peeling off, but in order to further increase the adhesive strength,
The rubber was held in an air bath for 60 minutes to allow the nickel layer to penetrate into the rubber, thereby producing a catheter having a nickel layer on the surface. Through these treatments, a nickel layer was uniformly formed on the surface of the catheter body. Even when this catheter was inserted into the human body, it did not irritate the human body or damage the inside of the body cavity.
〔実施例４〕
実施例１で無電解Ｃｕメッキを施しカテーテル本体の表
面に約０．２μｍの銅メッキを施して後、ＧＯＬＤ−８
（ワールドメタル社製）に浸漬して銅を金に置換し、接
着強度を上げるために８０℃のエアバス中に６０分保持
し金の層を均一に被着した。[Example 4] After applying electroless Cu plating in Example 1 and applying copper plating of approximately 0.2 μm to the surface of the catheter body, GOLD-8
(manufactured by World Metal Co., Ltd.) to replace copper with gold, and in order to increase the adhesive strength, it was held in an air bath at 80° C. for 60 minutes to uniformly coat the gold layer.
このカテーテルを人体に挿入しても人体を刺激し、体腔
内を損傷することはなかった
〔発明の効果〕
ゴムからなるカテーテル本体の少なくとも人体に挿入さ
れる部分に、人体に挿入したときに該人体を刺激するこ
となく、かつ殺菌作用或いは滅菌作用を有する金属層を
形成したことにより、金属の殺菌作用或いは滅菌作用で
感染症を防止でき、しかも、カテーテル本体に形成され
る金属層は極めて薄いため患者への挿入に際しても支障
とならず、感染症防止のための例えば膀胱の洗浄等の手
間も軽減でき、しかも、従来のテフロンコートのものに
殺菌作用或いは滅菌作用を有する金属を付着せしめたも
のより安価に提供しうる等の優れた効果がある。Even when this catheter was inserted into the human body, it did not stimulate the human body or damage the inside of the body cavity. [Effects of the Invention] By forming a metal layer that has a bactericidal or sterilizing effect without irritating the human body, the metal's bactericidal or sterilizing effect can prevent infections, and the metal layer formed on the catheter body is extremely thin. Therefore, there is no problem when inserting it into a patient, and the time and effort required for cleaning the bladder to prevent infections can be reduced.Moreover, it has a metal with bactericidal or sterilizing properties attached to the conventional Teflon coated product. It has excellent effects such as being able to provide it at a lower price than other products.
Claims (3)
体腔内に挿入される部分全体をアクチベーション処理し
て後無電解メッキ処理してカテーテル本体に殺菌作用或
いは滅菌作用を有する金属層を形成してなるカテーテル
。(1) A catheter made of rubber, at least the entire portion of which is inserted into the body cavity of the human body is activated, and then subjected to electroless plating to form a metal layer having a bactericidal or sterilizing effect on the catheter body. .
体腔内に挿入される部分全体をアルカリ性アルコール水
溶液で表面処理し、次いでアクチベーション処理を施し
て後無電解メッキ処理してカテーテル本体に殺菌作用或
いは滅菌作用を有する金属層を形成してなるカテーテル
。(2) At least the entire portion of the catheter body made of rubber that is inserted into the body cavity of the human body is surface-treated with an aqueous alkaline alcohol solution, and then subjected to activation treatment and then electroless plating to give the catheter body a bactericidal or sterilizing effect. A catheter formed by forming a metal layer having.
おいて、無電解メッキ処理で金属層を形成したのち３０
〜１５０℃の熱処理工程を施してなるカテーテル。(3) In the catheter according to claim 1 or claim 2, after forming the metal layer by electroless plating,
A catheter subjected to a heat treatment process at ~150°C.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2271488A JPH04146765A (en) | 1990-10-09 | 1990-10-09 | Catheter |
| EP91117058A EP0484680A1 (en) | 1990-10-09 | 1991-10-07 | Method of producing catheter and catheter thus obtained |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2271488A JPH04146765A (en) | 1990-10-09 | 1990-10-09 | Catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH04146765A true JPH04146765A (en) | 1992-05-20 |
Family
ID=17500749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2271488A Pending JPH04146765A (en) | 1990-10-09 | 1990-10-09 | Catheter |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH04146765A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018510003A (en) * | 2015-03-30 | 2018-04-12 | シー・アール・バード・インコーポレーテッドＣ Ｒ Ｂａｒｄ Ｉｎｃｏｒｐｏｒａｔｅｄ | Application of antibacterial agents to medical devices |
-
1990
- 1990-10-09 JP JP2271488A patent/JPH04146765A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018510003A (en) * | 2015-03-30 | 2018-04-12 | シー・アール・バード・インコーポレーテッドＣ Ｒ Ｂａｒｄ Ｉｎｃｏｒｐｏｒａｔｅｄ | Application of antibacterial agents to medical devices |
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