JPH025415Y2 - - Google Patents
Info
- Publication number
- JPH025415Y2 JPH025415Y2 JP1983155406U JP15540683U JPH025415Y2 JP H025415 Y2 JPH025415 Y2 JP H025415Y2 JP 1983155406 U JP1983155406 U JP 1983155406U JP 15540683 U JP15540683 U JP 15540683U JP H025415 Y2 JPH025415 Y2 JP H025415Y2
- Authority
- JP
- Japan
- Prior art keywords
- reagent
- sample
- container
- cleaning liquid
- pump
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003153 chemical reaction reagent Substances 0.000 claims description 78
- 239000007788 liquid Substances 0.000 claims description 19
- 238000004140 cleaning Methods 0.000 claims description 14
- 239000000126 substance Substances 0.000 claims description 7
- 238000007599 discharging Methods 0.000 claims description 2
- 238000005406 washing Methods 0.000 claims description 2
- 239000012530 fluid Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
- 238000002835 absorbance Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
Description
【考案の詳細な説明】
本考案は試薬の残量をモニターする機構を備え
た自動化学分析装置に関する。[Detailed Description of the Invention] The present invention relates to an automatic chemical analyzer equipped with a mechanism for monitoring the remaining amount of reagents.
自動化学分析装置は反応管において試料と分析
項目に応じた試薬とを反応させ、例えば、その吸
光度を測定する装置である。さて、各種の試薬は
多数の試料に対し、共通に使用される為、常時そ
の残量をチエツツクし、不足している試薬容器に
は試薬を補い、選択された試薬容器からは常に所
定量を割ることのない試薬が反応管に送られる様
にしている。この試薬の残量のチエツクは次の様
にして行なわれている。第１図は分析項目に応じ
た試薬を選択して、該選択した試薬を反応管に送
る機構を示したもので、試薬容器１ａ，１ｂ，１
ｃ，１ｄ，……には夫々別々の試薬が収容されて
おり、夫々に専用のポンプ２ａ，２ｂ，２ｃ，２
ｄ，……が設けられており、制御装置３からの指
令に従つてポンプが選択され、該制御装置の指令
により接続流路を切換る切換バルブ４を介して分
析項目に応じた試薬が反応管５に送られる。図中
６は水が収容された洗浄液槽で、前記各専用のポ
ンプに繋がつた流路に夫々設けられた手動コツク
７ａ，７ｂ，７ｃ，７ｄ，……の何れかを切換る
ことによつて、該切換られたコツクと同じ流路に
あるポンプにより該洗浄液槽から水が吸い上げら
れ、その流路が洗浄される。この様な機構におい
て、前記各ポンプはACモータによつて液の吸引
吐出が制御されており、１回転単位で吸引量が決
つている。そして、制御装置は選択されたポンプ
のACモータが作動する度に選択された試薬容器
の試薬量を初期値から減算していき、現在量をチ
エツクする様にしている。しかし乍ら、前記した
様に手動コツクを切換て洗浄液を流した時も、作
動させたポンプが担当している試薬容器の液量が
減算されてしまい、制御装置がチエツクした残量
と実際の残量と異なつてしまう。 An automatic chemical analyzer is a device that reacts a sample with a reagent according to an analysis item in a reaction tube and measures, for example, its absorbance. Now, since various reagents are commonly used for a large number of samples, it is necessary to constantly check the remaining amount, replenish any reagent containers that are in short supply, and always dispense the specified amount from the selected reagent container. The reagent is delivered to the reaction tube without breaking. The remaining amount of this reagent is checked as follows. Figure 1 shows a mechanism for selecting reagents according to analysis items and sending the selected reagents to reaction tubes.
c, 1d, .
A pump is selected according to a command from a control device 3, and a reagent corresponding to an analysis item is reacted via a switching valve 4 that switches the connecting flow path according to a command from the control device. It is sent to tube 5. In the figure, 6 is a cleaning liquid tank containing water, which can be cleaned by switching one of the manual pots 7a, 7b, 7c, 7d, . , Water is sucked up from the cleaning liquid tank by a pump located in the same flow path as the switched pot, and the flow path is cleaned. In such a mechanism, the suction and discharge of liquid in each of the pumps is controlled by an AC motor, and the amount of suction is determined in units of one rotation. Then, each time the AC motor of the selected pump operates, the control device subtracts the amount of reagent in the selected reagent container from the initial value and checks the current amount. However, as mentioned above, even when the manual control is switched to flow the cleaning solution, the amount of liquid in the reagent container handled by the operated pump is subtracted, and the remaining amount checked by the control device differs from the actual amount. It will differ from the remaining amount.
本考案はこの様な問題を解決することを目的と
したものである。 The present invention aims to solve such problems.
本考案は試料が収容された試料容器、該容器中
の試料を吸入して反応管中に吐出する吸入吐出手
段、試薬が収容された複数の試薬容器、洗浄液を
収容した洗浄液槽、制御装置の指令により吸上管
を前記複数の試薬管から１つの試薬管又は洗浄液
槽の何れかを選択する為の位置に移動させる機
構、該選択された試薬管又は洗浄液槽中の試薬又
は洗浄液を前記反応管又は排液槽中に吐出する１
台のポンプ、該制御装置の指令により該ポンプの
吸入吐出をコントロールするパルスモータ、及び
前記反応管中の試料と試薬の反応液を分析する手
段を具備し、前記制御装置に、選択した試薬容器
又は洗浄液槽と対応づけて該容器又は洗浄液槽か
ら吸い上げられた或いはそれらに残つた試薬量又
は洗浄液量を算出する働きを持たせた新規な自動
化学分析装置を提供するものである。 The present invention includes a sample container containing a sample, a suction and discharge means for sucking in the sample in the container and discharging it into a reaction tube, a plurality of reagent containers containing reagents, a cleaning liquid tank containing a cleaning liquid, and a control device. A mechanism for moving a suction tube to a position for selecting one of the plurality of reagent tubes or a washing liquid tank according to a command; 1 to discharge into a pipe or drain tank
a pump, a pulse motor for controlling suction and discharge of the pump according to commands from the control device, and means for analyzing a reaction solution of a sample and a reagent in the reaction tube, and a reagent container selected from the control device. Another object of the present invention is to provide a new automatic chemical analyzer having a function of calculating the amount of reagent or cleaning liquid sucked up from or remaining in the container or cleaning liquid tank in association with the cleaning liquid tank.
第２図は本考案の一実施例を示した自動化学分
析装置の概略図である。図中１１ａ，１１ｂ，１
１ｃ，……は試料容器で、実際にはターンテーブ
ルの如き回転装置に各容器が収容されている。１
２は試料吸上管で、試料吸上管移動機構１３によ
り上下に直線移動及び水平方向に回転可能に設け
てある。１４は流路切換器で、流路ａと前記移動
機構１３はフレキシブルなチユーブ１５で結ばれ
ており、流路ｂと試料用ポンプ１６とは導管１７
で結ばれている。又流路ｃは試薬用ポンプ１８と
導管１９で結ばれており、流路ｄは導管１９′を
介して排液槽２０に繋がつている。前記試料用ポ
ンプ１６には導管１７′を介して排液槽２０が繋
がつている。又、前記試薬用ポンプ１８はパルス
モータにより吸引吐出がコントロールされる様に
成しており、後述するCPU２９から該パルスモ
ータに与えるパルスの数により吸引量が決められ
ている。そして該ポンプにはフレキシブルなチユ
ーブ２１を介して試薬吸上管移動機構２２が繋が
つている。該移動機構は試薬吸上管２３を上下及
び水平方向に移動させて適宜な試薬容器２４ａ，
２４ｂ，２４ｃ，……又は水槽２５を選択させる
ようになしてある。２６は反応管で、該反応管を
挾んで一方のサイドには光源２７、他方のサイド
には検出器２８が配置されている。該検出器の出
力は中央制御機構（以後CPUと称す）２９と記
録計３０に供給される。３５は警報器で、前記試
薬容器の試薬の残量が基準量を下回ると警報を発
する。尚、３１，３２，３３は前記CPU２９の
指令により作動する第１、第２、第３制御装置
で、夫々、前記試料吸上管移動機構１３、ポンプ
１６、試薬吸上管移動機構２２の動作をコントロ
ールする。 FIG. 2 is a schematic diagram of an automatic chemical analyzer showing an embodiment of the present invention. 11a, 11b, 1 in the figure
1c, . . . are sample containers, and each container is actually housed in a rotating device such as a turntable. 1
Reference numeral 2 denotes a sample suction tube, which is provided so as to be vertically linearly movable and horizontally rotatable by a sample suction tube moving mechanism 13. 14 is a flow path switching device, flow path a and the moving mechanism 13 are connected by a flexible tube 15, and flow path b and the sample pump 16 are connected by a conduit 17.
are tied together. The flow path c is connected to the reagent pump 18 by a conduit 19, and the flow path d is connected to a drain tank 20 via a conduit 19'. A drain tank 20 is connected to the sample pump 16 via a conduit 17'. Further, the reagent pump 18 is configured such that its suction and discharge is controlled by a pulse motor, and the amount of suction is determined by the number of pulses given to the pulse motor from a CPU 29, which will be described later. A reagent suction tube moving mechanism 22 is connected to the pump via a flexible tube 21. The moving mechanism moves the reagent suction tube 23 vertically and horizontally to appropriate reagent containers 24a,
24b, 24c, . . . or the water tank 25 can be selected. 26 is a reaction tube, and a light source 27 is placed on one side of the reaction tube, and a detector 28 is placed on the other side. The output of the detector is supplied to a central control unit (hereinafter referred to as CPU) 29 and a recorder 30. Reference numeral 35 denotes an alarm, which issues an alarm when the remaining amount of reagent in the reagent container falls below a reference amount. Reference numerals 31, 32, and 33 are first, second, and third control devices that operate according to instructions from the CPU 29, and control the operations of the sample suction tube moving mechanism 13, the pump 16, and the reagent suction tube moving mechanism 22, respectively. control.
斯くの如き装置において、初め、流路切換器１
４では流路ａと流路ｂとが繋がつており、CPU
１９の指令を受けた第１制御装置３１により試料
吸上管移動機構１３は試料吸上管１２を例えば試
料容器１１ａの中に挿入される。次に該CPUの
指令をうけた第２制御装置３２により試料用ポン
プ１６は作動し、該試料容器１１ａから所定量の
試料を吸い上げる。該吸上管は移動機構１３によ
り回転し、反応管２６の中に挿入される。ここ
で、前記流路切換器１４は流路を切換え、流路ａ
と流路ｃを繋ぐ。この時、前記CPU２９はは選
択すべき試薬容器のナンバーの指令を第３制御装
置３３に送るので、試薬吸上管移動機構２２は該
制御装置の指令に従い、試薬吸上管２３を例えば
試薬容器２４ａ中に挿入させる。次に該CPUは
吸引すべき量の指令を第４制御装置３４に送るの
で、該制御装置は該指令に対応したパルス数の指
令を試薬用ポンプをコントロールしているパルス
モータに送る。該パルスモータにより試薬用ポン
プ１８は作動し、該試薬容器からパルス数に対応
した量の試薬を吸い上げ前記試料吸上管１２の中
の試料を試薬と共に前記反応管２６の中に押出
す。この時、前記CPUは予め各試薬容器に最初
に収容した試薬量に対応したパルス数を試薬容器
のナンバーと対応付て記憶しており、前記選択し
た試薬容器２４ａに対して記憶していたパルス数
から前記パルスモータに送つたパルス数を差し引
き該試薬容器の試薬の残量を演算する。前記反応
管２６への押し出しが終ると、前記試料吸上管１
２は吸上管移動機構１３によつて該反応管２６か
ら抜取られ、途中で洗浄され、初めの位置に戻
る。又、前記試薬吸上管２３は前記選択された試
薬が次の試料に対しても使用されるなら、そのま
まの位置が維持されるが、他の試薬が選択される
場合、第３制御装置３３を介して前記CPU２９
の指令を受けた試薬吸上管移動装置２２により、
水槽２５の中に挿入される。そして、該CPUは
吸引すべき量の指令を第４制御装置３４に送るの
で、該制御装置は該指令に対応したパルス数の指
令を試薬用ポンプ１８をコントロールしているパ
ルスモータに送る。該パルスモータにより試薬用
ポンプ１８は作動し、該水槽からパルス数に対応
した量の水を吸い上げ、前記チユーブ２１及び導
管１９，１９′を通じて排液槽２０に排出され、
試薬吸上管２３、試料２１及び導管１９の内部が
洗浄される。この時も前記CPUは水槽中の水の
残量を演算しておく。更に、反応管２６では吸光
度が測定され、前記試薬容器のナンバーと該容器
内の試薬の残量と共に吸光度が表示装置３０に表
示される。又、もし該残量が基準量を下回ると、
該CPUの指令により警報装置３５が警報を発す
るので、オペレータはその時、該当する試薬容器
に試薬を元の量になるまで補充する。尚、CPU
は各容器内の液体の残量を求める様にしたが、該
液体の消費量を求める様にしてもよい。又、試薬
の残量或いは消費量を常に表示する必要は無く、
残量が基準値を下回つた時に表示或いは警報を発
する様にしてもよい。 In such a device, initially, the flow path switching device 1
In 4, flow path a and flow path b are connected, and the CPU
In response to the first control device 31 receiving the command No. 19, the sample suction tube moving mechanism 13 inserts the sample suction tube 12 into, for example, the sample container 11a. Next, the sample pump 16 is activated by the second control device 32 in response to a command from the CPU, and sucks up a predetermined amount of sample from the sample container 11a. The suction tube is rotated by the moving mechanism 13 and inserted into the reaction tube 26. Here, the flow path switching device 14 switches the flow path, and the flow path a
and connect flow path c. At this time, the CPU 29 sends a command for the number of the reagent container to be selected to the third control device 33, so the reagent suction tube moving mechanism 22 follows the command from the control device to move the reagent suction tube 23 to, for example, a reagent container. 24a. Next, the CPU sends a command for the amount to be aspirated to the fourth control device 34, and the control device sends a command for the number of pulses corresponding to the command to the pulse motor controlling the reagent pump. The reagent pump 18 is operated by the pulse motor, sucks up an amount of reagent corresponding to the number of pulses from the reagent container, and pushes the sample in the sample suction tube 12 into the reaction tube 26 together with the reagent. At this time, the CPU has previously stored the number of pulses corresponding to the amount of reagent initially contained in each reagent container in association with the number of the reagent container, and the pulse number stored for the selected reagent container 24a. The remaining amount of reagent in the reagent container is calculated by subtracting the number of pulses sent to the pulse motor from the number. When the extrusion into the reaction tube 26 is completed, the sample suction tube 1
2 is pulled out from the reaction tube 26 by the suction tube moving mechanism 13, washed along the way, and returned to the initial position. Further, if the selected reagent is used for the next sample, the reagent suction tube 23 remains in the same position, but if another reagent is selected, the third control device 33 said CPU29 via
The reagent suction tube moving device 22 receives the command,
It is inserted into the water tank 25. Then, the CPU sends a command for the amount to be aspirated to the fourth control device 34, and the control device sends a command for the number of pulses corresponding to the command to the pulse motor controlling the reagent pump 18. The reagent pump 18 is operated by the pulse motor, sucks up an amount of water corresponding to the number of pulses from the water tank, and discharges it to the drain tank 20 through the tube 21 and conduits 19, 19'.
The insides of the reagent suction tube 23, sample 21, and conduit 19 are cleaned. At this time as well, the CPU calculates the remaining amount of water in the aquarium. Furthermore, the absorbance is measured in the reaction tube 26, and the absorbance is displayed on the display device 30 together with the number of the reagent container and the remaining amount of the reagent in the container. Also, if the remaining amount falls below the standard amount,
The alarm device 35 issues an alarm in response to a command from the CPU, and the operator then replenishes the corresponding reagent container with the reagent to the original amount. Furthermore, CPU
Although the remaining amount of liquid in each container is determined, the consumption amount of the liquid may also be determined. Also, there is no need to always display the remaining or consumed amount of reagents.
It may also be possible to display or issue an alarm when the remaining amount falls below a reference value.
本考案によれば、各試薬容器及び水槽から試薬
又は水を吸引する為のポンプを一台設け、試薬を
吸引する場合、試薬吸上管を選択すべき試薬容器
の中に移動させ、流路を洗浄する場合、手動コツ
クの切換をせずに試薬吸上管を該水槽中に移動さ
せることによつてなし、選択された試薬容器又は
水槽中の試薬又は水の残量を前記ポンプの吸引吐
出をコントロールするパルスモータへのパルス数
に基づいて検出しているので、各試薬容器中の試
薬の残量を精確にチエツクすることが出来る。 According to the present invention, one pump is provided for sucking reagent or water from each reagent container and water tank, and when sucking the reagent, the reagent suction tube is moved into the selected reagent container, and the flow path is When cleaning the reagent container or water tank, the remaining amount of reagent or water in the selected reagent container or water tank is suctioned by the pump by moving the reagent suction tube into the water tank without switching the manual switch. Since the detection is based on the number of pulses sent to the pulse motor that controls the discharge, it is possible to accurately check the amount of reagent remaining in each reagent container.
第１図は自動化学分析装置の従来の試薬送液機
構の概略図、第２図は本考案の一実施例として示
した自動化学分析装置の概略図である。
１１ａ，１１ｂ，１１ｃ，……：試料容器、１
２：試料吸上管、１３：試料吸上管移動機構、１
４：流路切換器、１６：試料用ポンプ、１８：試
薬用ポンプ、２０，２０′：排液槽、２２：試薬
吸上管移動機構、２３：試薬吸上管、２４ａ，２
４ｂ，２４ｃ……：試薬容器、２５：水槽、２
６：反応管、２７：光源、２８：検出器、２９：
中央制御機構（CPU）、３０：記録計。
FIG. 1 is a schematic diagram of a conventional reagent feeding mechanism of an automatic chemical analyzer, and FIG. 2 is a schematic diagram of an automatic chemical analyzer shown as an embodiment of the present invention. 11a, 11b, 11c, ...: sample container, 1
2: Sample suction tube, 13: Sample suction tube moving mechanism, 1
4: Flow path switcher, 16: Sample pump, 18: Reagent pump, 20, 20': Drain tank, 22: Reagent suction tube moving mechanism, 23: Reagent suction tube, 24a, 2
4b, 24c...: Reagent container, 25: Water tank, 2
6: reaction tube, 27: light source, 28: detector, 29:
Central control unit (CPU), 30: Recorder.
Claims (1)
吸入して反応管中に吐出する吸入吐出手段、試薬
が収容された複数の試薬容器、洗浄液を収容した
洗浄液槽、制御装置の指令により吸上管を前記複
数の試薬管から１つの試薬管又は洗浄液槽の何れ
かを選択する為の位置に移動させる機構、該選択
された試薬管又は洗浄液槽中の試薬又は洗浄液を
前記反応管又は排液槽中に吐出する１台のポン
プ、該制御装置の指令により該ポンプの吸入吐出
をコントロールするパルスモータ、及び前記反応
管中の試料と試薬の反応液を分析する手段を具備
し、前記制御装置に、選択した試薬容器又は洗浄
液槽と対応づけて該容器又は洗浄液槽に吸い上げ
られた或いはそれらに残つた試薬量又は洗浄液量
を算出する働きを持たせた自動化学分析装置。 A sample container containing a sample, a suction/discharge means for sucking in the sample in the container and discharging it into a reaction tube, a plurality of reagent containers containing reagents, a cleaning liquid tank containing a cleaning liquid, A mechanism for moving the upper tube to a position for selecting one of the reagent tubes or washing liquid tank from the plurality of reagent tubes; A pump that discharges fluid into the liquid tank, a pulse motor that controls suction and discharge of the pump according to commands from the control device, and means for analyzing the reaction solution of the sample and reagent in the reaction tube, and the control device An automatic chemical analysis device in which the device has a function of calculating the amount of reagent or cleaning liquid sucked up into or remaining in a selected reagent container or cleaning liquid tank in association with the selected reagent container or cleaning liquid tank.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15540683U JPS6064263U (en) | 1983-10-06 | 1983-10-06 | automatic chemical analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15540683U JPS6064263U (en) | 1983-10-06 | 1983-10-06 | automatic chemical analyzer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6064263U JPS6064263U (en) | 1985-05-07 |
| JPH025415Y2 true JPH025415Y2 (en) | 1990-02-08 |
Family
ID=30343240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15540683U Granted JPS6064263U (en) | 1983-10-06 | 1983-10-06 | automatic chemical analyzer |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6064263U (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH084618Y2 (en) * | 1990-01-19 | 1996-02-07 | 日本テクトロン株式会社 | Overflow confirmation mechanism |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS545790A (en) * | 1977-06-15 | 1979-01-17 | Hitachi Ltd | Automatic analyzer of single channel multiple item |
| JPS5654357A (en) * | 1979-10-11 | 1981-05-14 | Hitachi Ltd | Dispensing method |
| JPS5782769A (en) * | 1980-11-10 | 1982-05-24 | Hitachi Ltd | Automatic analyzing device |
-
1983
- 1983-10-06 JP JP15540683U patent/JPS6064263U/en active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS545790A (en) * | 1977-06-15 | 1979-01-17 | Hitachi Ltd | Automatic analyzer of single channel multiple item |
| JPS5654357A (en) * | 1979-10-11 | 1981-05-14 | Hitachi Ltd | Dispensing method |
| JPS5782769A (en) * | 1980-11-10 | 1982-05-24 | Hitachi Ltd | Automatic analyzing device |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6064263U (en) | 1985-05-07 |
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