JP7234319B2 - 一酸化窒素の合成のためのシステム及び方法 - Google Patents
一酸化窒素の合成のためのシステム及び方法 Download PDFInfo
- Publication number
- JP7234319B2 JP7234319B2 JP2021149832A JP2021149832A JP7234319B2 JP 7234319 B2 JP7234319 B2 JP 7234319B2 JP 2021149832 A JP2021149832 A JP 2021149832A JP 2021149832 A JP2021149832 A JP 2021149832A JP 7234319 B2 JP7234319 B2 JP 7234319B2
- Authority
- JP
- Japan
- Prior art keywords
- nitric oxide
- generator
- gas
- filter
- oxide generator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0087—Environmental safety or protection means, e.g. preventing explosion
- A61M16/009—Removing used or expired gases or anaesthetic vapours
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/105—Filters
- A61M16/1055—Filters bacterial
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/105—Filters
- A61M16/106—Filters in a path
- A61M16/107—Filters in a path in the inspiratory path
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B21/00—Nitrogen; Compounds thereof
- C01B21/20—Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
- C01B21/24—Nitric oxide (NO)
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B21/00—Nitrogen; Compounds thereof
- C01B21/20—Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
- C01B21/24—Nitric oxide (NO)
- C01B21/30—Preparation by oxidation of nitrogen
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B21/00—Nitrogen; Compounds thereof
- C01B21/20—Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
- C01B21/24—Nitric oxide (NO)
- C01B21/30—Preparation by oxidation of nitrogen
- C01B21/32—Apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
- A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
- A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
- A61M2016/102—Measuring a parameter of the content of the delivered gas
- A61M2016/1025—Measuring a parameter of the content of the delivered gas the O2 concentration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
- A61M2016/102—Measuring a parameter of the content of the delivered gas
- A61M2016/1035—Measuring a parameter of the content of the delivered gas the anaesthetic agent concentration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0266—Nitrogen (N)
- A61M2202/0275—Nitric oxide [NO]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/20—Air quality improvement or preservation, e.g. vehicle emission control or emission reduction by using catalytic converters
Landscapes
- Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Ecology (AREA)
- Environmental & Geological Engineering (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Treating Waste Gases (AREA)
- Exhaust Gas After Treatment (AREA)
Description
以下の例は、詳細には、呼吸器系100、200及び/又は一酸化窒素発生器14、102、201及び301を使用又は実施する方法を説明し、当業者はその原理をより容易に理解することができる。以下の例は、説明のために提示されただけで限定することは全く意図しない。
様々な酸素及び窒素濃度で一酸化窒素及び二酸化窒素生成を測定する。
連続運転中の一酸化窒素及び二酸化窒素濃度の10日間の測定
B、N、P、及びHを変化させたときの一酸化窒素及び二酸化窒素生成の測定
変化する大気圧での一酸化窒素及び二酸化窒素生成の測定
様々な酸素及び窒素濃度で一酸化窒素発生器14の捕集剤42に流入及び流出する一酸化窒素及び二酸化窒素濃度の測定
一酸化窒素発生器102の捕集剤42に出入りする一酸化窒素及び二酸化窒素濃度の測定
一酸化窒素発生器14によって生成されたオゾン濃度の測定及び捕集
電極侵食
電極組成を変えることによる二酸化窒素発生の最小化
一酸化窒素発生器102の膜104を通る一酸化窒素及び二酸化窒素拡散速度の測定
麻酔ラムの呼吸器系10を用いた空気からの連続的な一酸化窒素の生成
麻酔ラムの呼吸器系100を用いた大気からの連続的な一酸化窒素の生成
麻酔ラムの呼吸器系100を用いた空気からの断続的な一酸化窒素の生成
Claims (18)
- 一酸化窒素ガスを生成するように構成された一酸化窒素発生器と、
前記一酸化窒素発生器の下流に配置されて少なくとも二酸化窒素(NO 2 )を取り除く捕集剤と、
前記一酸化窒素ガスを患者に送達するように構成された吸気ライン上に配置され、前記一酸化窒素ガスから粒子を濾過して前記吸気ラインを介して前記粒子の吸入を防止するように構成されたフィルタと、
前記一酸化窒素発生器及び1つ又は複数のセンサと通信し、前記1つ又は複数のセンサからの情報を用いて、前記一酸化窒素発生器のタイミングおよびスパーク特性を制御する電気信号を前記一酸化窒素発生器に供給することにより、前記一酸化窒素発生器によって生成される前記一酸化窒素ガス中の一酸化窒素の量を調節するように構成された少なくとも1つのコントローラと、を備え、
前記少なくとも1つのコントローラが、1つまたは複数のセンサによって測定された二酸化窒素の濃度が所定の値を超えるかどうかを判断することで前記捕集剤の状態を監視し、その結果、前記少なくとも1つのコントローラが、前記捕集剤を交換するようユーザに指示すると共に、前記電気信号を前記一酸化窒素発生器へ供給するのを停止して一酸化窒素の生成を停止させる、
一酸化窒素(NO)を生成するための装置。 - 前記フィルタは、前記一酸化窒素発生器の下流に流れる粒子を濾過するように構成される、請求項1に記載の装置。
- 前記フィルタが、0.22マイクロメートルを超える直径を有する粒子を濾過するように構成される、請求項1に記載の装置。
- 前記吸気ライン上の前記フィルタは、生成された前記一酸化窒素ガスが患者に到達する前に二酸化窒素に酸化されることを低減する、請求項1に記載の装置。
- 前記1つ又は複数のセンサは、ガスの流量、前記一酸化窒素発生器の上流の酸素濃度、
前記一酸化窒素発生器の下流の一酸化窒素濃度、及び前記一酸化窒素発生器の下流の二酸化窒素濃度のうちの少なくとも1つを測定するように構成される、請求項1に記載の装置。 - 前記一酸化窒素発生器の下流に配置された捕集剤をさらに備える、請求項1に記載の装置。
- 前記捕集剤が前記吸気ライン上に配置されている、請求項6に記載の装置。
- 前記吸気ライン内のガスの流量を測定するように構成され、前記吸気ライン上に配置された気道流量計をさらに備える、請求項1に記載の装置。
- 前記コントローラは、患者の吸気中に前記電気信号を前記一酸化窒素発生器に供給するように構成される、請求項1に記載の装置。
- 前記コントローラは、前記吸気ラインに配置された気道流量計によって測定された流量、前記吸気ライン内の温度、呼気ライン内の温度、前記吸気ラインの圧力、及び前記呼気ラインの圧力のうちの少なくとも1つに基づいて吸気を検出するように構成される、請求項9に記載の装置。
- 前記一酸化窒素発生器は、前記フィルタの上流の前記吸気ライン上に配置される、請求項1に記載の装置。
- 一酸化窒素ガスを生成するように構成され、吸気ラインに連通する一酸化窒素発生器と、
前記一酸化窒素ガスを患者に送達するように構成された前記吸気ライン上に配置され、前記一酸化窒素ガスから粒子を濾過して前記吸気ラインを介して前記粒子の吸入を防止するように構成されたフィルタと、
前記一酸化窒素発生器の下流に配置され、少なくとも二酸化窒素を濾過する捕集剤と、
前記吸気ラインに連通する前記一酸化窒素発生器、1つ又は複数のセンサ、及び気道流量計と通信し、前記一酸化窒素発生器に前記一酸化窒素発生器のタイミングおよびスパーク特性を制御する電気信号を供給するように構成されたコントローラと、を備え、
前記一酸化窒素発生器のタイミングおよびスパーク特性によって前記一酸化窒素発生器によって生成される一酸化窒素濃度が決定され、
前記少なくとも1つのコントローラが、1つまたは複数のセンサによって測定された二酸化窒素の濃度が所定の値を超えるかどうかを判断することで前記捕集剤の状態を監視し、その結果、前記少なくとも1つのコントローラが、前記捕集剤を交換するようユーザに指示すると共に、前記電気信号を前記一酸化窒素発生器へ供給するのを停止して一酸化窒素の生成を停止させる、
一酸化窒素を生成するための装置。 - 前記フィルタは、前記一酸化窒素発生器の下流に流れる粒子を濾過するように構成される、請求項12に記載の装置。
- 前記フィルタが、0.22マイクロメートルを超える直径を有する粒子を濾過するように構成される、請求項12に記載の装置。
- 前記吸気ライン上の前記フィルタは、生成された前記一酸化窒素ガスが患者に到達する前に二酸化窒素に酸化されることを低減する、請求項12に記載の装置。
- 前記吸気ラインに前記捕集剤が配置されている、請求項12に記載の装置。
- 前記1つ又は複数のセンサが、前記一酸化窒素発生器の上流に配置された酸素センサ、
前記一酸化窒素発生器の下流に配置された一酸化窒素センサ、及び前記一酸化窒素発生器の下流に配置された二酸化窒素センサを含む、請求項12に記載の装置。 - 前記気道流量計が吸気の指標を提供する、請求項12に記載の装置。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2023024982A JP2023059931A (ja) | 2014-10-20 | 2023-02-21 | 一酸化窒素の合成のためのシステム及び方法 |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462065825P | 2014-10-20 | 2014-10-20 | |
US62/065,825 | 2014-10-20 | ||
US201462077806P | 2014-11-10 | 2014-11-10 | |
US62/077,806 | 2014-11-10 | ||
JP2017539531A JP6947633B2 (ja) | 2014-10-20 | 2015-10-20 | 一酸化窒素の合成のためのシステム及び方法 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017539531A Division JP6947633B2 (ja) | 2014-10-20 | 2015-10-20 | 一酸化窒素の合成のためのシステム及び方法 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2023024982A Division JP2023059931A (ja) | 2014-10-20 | 2023-02-21 | 一酸化窒素の合成のためのシステム及び方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022000177A JP2022000177A (ja) | 2022-01-04 |
JP7234319B2 true JP7234319B2 (ja) | 2023-03-07 |
Family
ID=55761418
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017539531A Active JP6947633B2 (ja) | 2014-10-20 | 2015-10-20 | 一酸化窒素の合成のためのシステム及び方法 |
JP2021149832A Active JP7234319B2 (ja) | 2014-10-20 | 2021-09-15 | 一酸化窒素の合成のためのシステム及び方法 |
JP2023024982A Pending JP2023059931A (ja) | 2014-10-20 | 2023-02-21 | 一酸化窒素の合成のためのシステム及び方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017539531A Active JP6947633B2 (ja) | 2014-10-20 | 2015-10-20 | 一酸化窒素の合成のためのシステム及び方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2023024982A Pending JP2023059931A (ja) | 2014-10-20 | 2023-02-21 | 一酸化窒素の合成のためのシステム及び方法 |
Country Status (12)
Country | Link |
---|---|
US (2) | US11497878B2 (ja) |
EP (2) | EP3209359B1 (ja) |
JP (3) | JP6947633B2 (ja) |
KR (1) | KR20170072293A (ja) |
CN (2) | CN116177503A (ja) |
AU (2) | AU2015336055B2 (ja) |
BR (1) | BR112017007841B1 (ja) |
CA (1) | CA2963874C (ja) |
ES (1) | ES2822215T3 (ja) |
MX (1) | MX2017004796A (ja) |
RU (1) | RU2730960C2 (ja) |
WO (1) | WO2016064863A1 (ja) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2692650C2 (ru) | 2013-03-15 | 2019-06-25 | Взе Дженерал Хоспитал Корпорейшн | Синтез оксида азота для вдыхания |
CN109310842B (zh) | 2016-03-25 | 2022-08-19 | 通用医疗公司 | 用于电等离子体合成一氧化氮的输送***和方法 |
CN109069786B (zh) * | 2016-05-04 | 2022-06-07 | 马林克罗特医疗产品知识产权公司 | 用于与通气机和/或一氧化氮输送***有关的患者呼吸回路的湿度调节样品气体的设备 |
JP2019528868A (ja) * | 2016-09-10 | 2019-10-17 | ベロ バイオテック エルエルシー | 移動式一酸化窒素送達システム及び方法 |
CN110573454B (zh) * | 2017-02-27 | 2021-08-20 | 第三极股份有限公司 | 生成一氧化氮的***和方法 |
KR20220137155A (ko) * | 2017-02-27 | 2022-10-11 | 써드 폴, 아이엔씨. | 산화질소의 이동식 생성을 위한 시스템 및 방법 |
MX2020010523A (es) | 2017-02-27 | 2021-02-09 | Third Pole Inc | Sistemas y metodos para generar oxido nitrico. |
CA3058472C (en) * | 2017-03-31 | 2020-05-26 | The General Hospital Corporation | Systems and methods for a cooled nitric oxide generator |
JP7442207B2 (ja) * | 2018-09-27 | 2024-03-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | ガス送達デバイス |
CN110872714B (zh) * | 2018-10-22 | 2024-05-14 | 南京诺令生物科技有限公司 | 一种便携式一氧化氮制造机 |
WO2020084992A1 (ja) | 2018-10-25 | 2020-04-30 | 帝人ファーマ株式会社 | 一酸化窒素投与装置 |
KR102626986B1 (ko) * | 2018-10-25 | 2024-01-19 | 데이진 화-마 가부시키가이샤 | 중계 투여 장치 및 일산화질소 투여 시스템 |
ES2972073T3 (es) * | 2018-10-25 | 2024-06-11 | Teijin Pharma Ltd | Dispositivo de administración de óxido nítrico |
JP7004841B2 (ja) * | 2018-10-25 | 2022-01-21 | 帝人ファーマ株式会社 | 一酸化窒素投与装置 |
CN109568745B (zh) * | 2018-11-21 | 2021-11-19 | 史海权 | 一种医用一氧化氮供气***及方法 |
WO2020232397A1 (en) | 2019-05-15 | 2020-11-19 | Third Pole, Inc. | Electrodes for nitric oxide generation |
WO2020232419A1 (en) * | 2019-05-15 | 2020-11-19 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
EP4069069A4 (en) | 2020-01-11 | 2024-07-03 | Third Pole Inc | SYSTEMS AND METHODS FOR GENERATING NITRIC OXIDE WITH HUMIDITY CONTROL |
WO2021248142A2 (en) * | 2020-06-05 | 2021-12-09 | The General Hospital Corporation | Systems and methods for nitric oxide generation and treatment |
US20210395905A1 (en) | 2020-06-18 | 2021-12-23 | Third Pole, Inc. | Systems and methods for preventing and treating infections with nitric oxide |
WO2022064395A1 (pt) * | 2020-09-22 | 2022-03-31 | Jorge Alberto Ferreira Noras | Aparelho portátil individual e conjunto para fornecimento de ar com filtragem melhorada |
CA3211562A1 (en) * | 2021-03-11 | 2022-09-15 | Nathaniel G. Jackson | Systems and methods for nitric oxide generation and delivery |
US11975139B2 (en) | 2021-09-23 | 2024-05-07 | Third Pole, Inc. | Systems and methods for delivering nitric oxide |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010031230A1 (en) | 1998-05-27 | 2001-10-18 | Siemens Aktiengesellschaft | Apparatus for plasma-chemical production of nitrogen monoxide |
JP2004065636A (ja) | 2002-08-07 | 2004-03-04 | Osaka Industrial Promotion Organization | 可搬型医療用一酸化窒素発生装置及び可搬型医療用一酸化窒素吸入装置 |
WO2014144151A1 (en) | 2013-03-15 | 2014-09-18 | The General Hospital Corporation | Inspiratory synthesis of nitric oxide |
Family Cites Families (131)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2525938A (en) | 1946-11-01 | 1950-10-17 | Koppers Co Inc | Electrochemical apparatus with adjustable electrode |
US2485481A (en) | 1949-06-17 | 1949-10-18 | Koppers Co Inc | Electrochemical production of nitrogen oxide |
US2684448A (en) | 1952-06-03 | 1954-07-20 | Us Navy | Controllable pulse generator |
US3047370A (en) | 1959-07-28 | 1962-07-31 | Grace W R & Co | Transparent soda lime cartridge |
US3225309A (en) | 1963-12-05 | 1965-12-21 | John H Phelps | Pulse wave generator with independent control of pulse repetition frequency and duty cycle |
IL57239A (en) | 1979-05-08 | 1982-04-30 | Alamaro Moshe | Production of nitric oxides |
NO803666L (no) | 1980-12-03 | 1982-06-04 | Moshe Alamaro | Modifisert birkeland/eyde - prosess ii |
US4500563A (en) | 1982-12-15 | 1985-02-19 | Pacific Western Systems, Inc. | Independently variably controlled pulsed R.F. plasma chemical vapor processing |
US4680694A (en) | 1985-04-22 | 1987-07-14 | National Distillers And Chemical Corporation | Ozonator power supply |
US4705670A (en) | 1985-09-03 | 1987-11-10 | Hare Louis R O | Multiple oxidation nitrogen fixation |
US4695358A (en) | 1985-11-08 | 1987-09-22 | Florida State University | Method of removing SO2, NOX and particles from gas mixtures using streamer corona |
US4816229A (en) | 1986-07-09 | 1989-03-28 | American Ozone Technology, Inc. | Ozone apparatus |
US4877589A (en) | 1988-09-19 | 1989-10-31 | Hare Louis R O | Nitrogen fixation by electric arc and catalyst |
US5378436A (en) | 1990-03-06 | 1995-01-03 | Mitsubishi Denki Kabushiki Kaisha | Method and apparatus for producing hydrogen peroxide |
JPH04132560A (ja) | 1990-09-21 | 1992-05-06 | Tottori Univ | 医療用酸素濃縮装置および方法 |
DE10299002I1 (de) | 1990-12-05 | 2012-07-05 | Gen Hospital Corp | Verwendung von No zur Behandlung oder Praevention der Bronchokonstriktion |
US5396882A (en) | 1992-03-11 | 1995-03-14 | The General Hospital Corporation | Generation of nitric oxide from air for medical uses |
US5285372A (en) | 1991-10-23 | 1994-02-08 | Henkel Corporation | Power supply for an ozone generator with a bridge inverter |
DE4202025C2 (de) * | 1992-01-25 | 1995-02-02 | Draegerwerk Ag | Gebläseunterstütztes Atemschutzgerät mit einstellbarer Gebläseleistung |
US6290683B1 (en) | 1992-04-29 | 2001-09-18 | Mali-Tech Ltd. | Skin piercing needle assembly |
ES2106107T3 (es) | 1992-05-21 | 1997-11-01 | Siemens Ag | Procedimiento y dispositivo para el control y supervision independiente de un flujo de gas muy pequeño. |
CA2075789C (en) | 1992-08-11 | 1998-12-22 | Amir Salama | Inner electrode for an ozone generator, ozone generator containing said electrode and method of use of said ozone generator |
US5546935A (en) | 1993-03-09 | 1996-08-20 | Medamicus, Inc. | Endotracheal tube mounted pressure transducer |
EP0621051B1 (de) | 1993-04-17 | 2001-08-22 | MESSER GRIESHEIM AUSTRIA Ges.m.b.H. | Gerät zur kontrollierten Zudosierung von NO zur Atemluft von Patienten |
GB9309294D0 (en) | 1993-05-06 | 1993-06-16 | Smiths Ind Public Ltd | Heaters and heated devices |
BR9303645A (pt) * | 1993-08-31 | 1995-04-25 | Oliveira Marques Antonio Se De | Processo de fabricação de produto alimentício |
ATE153311T1 (de) | 1993-09-13 | 1997-06-15 | Aga Ab | Verfahren und vorrichtung zum erzeugen von stickstoffoxyde |
GB9320978D0 (en) | 1993-10-12 | 1993-12-01 | Higenbottam Timohy W | Nitric oxide treatment |
US5558083A (en) | 1993-11-22 | 1996-09-24 | Ohmeda Inc. | Nitric oxide delivery system |
DE19534248A1 (de) * | 1995-09-18 | 1997-03-20 | Hoechst Ag | Verfahren zur Herstellung von NO¶2¶-freiem Stickstoffmonoxid |
RU2072241C1 (ru) | 1995-09-20 | 1997-01-27 | Панина Елена Владимировна | Способ формирования дыхательной газовой смеси и аппарат для его осуществления |
SE9504310D0 (sv) | 1995-12-01 | 1995-12-01 | Siemens Elema Ab | Doseringsanordning |
US5692495A (en) * | 1996-04-02 | 1997-12-02 | The Boc Group, Inc. | Method and apparatus for the production of nitric oxide gas mixture |
US5732693A (en) | 1996-10-02 | 1998-03-31 | Ohmeda Inc. | Pause control of nitric oxide therapy |
US5752504A (en) | 1996-12-13 | 1998-05-19 | Ohmeda Inc. | System for monitoring therapy during calibration |
EP0973443B1 (de) | 1997-01-17 | 2006-03-22 | INO-Therapeutics GmbH | Gesteuertes gasversorgungssystem |
US6164276A (en) | 1997-05-16 | 2000-12-26 | Datex-Ohmeda, Inc. | Accurate dose nitric oxide pulse delivery device with monitoring and alarms |
US6125846A (en) | 1997-05-16 | 2000-10-03 | Datex-Ohmeda, Inc. | Purge system for nitric oxide administration apparatus |
FI974148A (fi) | 1997-11-05 | 1999-05-06 | Instrumentarium Oy | Menetelmä ja sovitelma hengityslaitteen yhteydessä |
US6109260A (en) | 1998-02-18 | 2000-08-29 | Datex-Ohmeda, Inc. | Nitric oxide administration device with timed pulse |
US6089229A (en) | 1998-05-26 | 2000-07-18 | Datex-Ohmeda, Inc. | High concentration no pulse delivery device |
JP2000102616A (ja) | 1998-09-28 | 2000-04-11 | Shusuke Akiyama | 医療用一酸化窒素吸入装置 |
US6224653B1 (en) | 1998-12-29 | 2001-05-01 | Pulsatron Technology Corporation | Electrostatic method and means for removing contaminants from gases |
US6197091B1 (en) | 1999-03-05 | 2001-03-06 | The Boc Group, Inc. | Ozone purification process |
US7516742B2 (en) | 1999-11-24 | 2009-04-14 | Cardinal Health 207, Inc. | Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing |
US6581599B1 (en) | 1999-11-24 | 2003-06-24 | Sensormedics Corporation | Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients |
US6758214B2 (en) * | 2000-01-28 | 2004-07-06 | Cyterra Corporation | Simple nitric oxide generator for ambulatory and/or bedside inhaled no treatment |
JP2003525801A (ja) | 2000-03-09 | 2003-09-02 | リンドジイ、マリー、ドハポート | 携帯型自動乗物キャビン空気清浄機 |
WO2002004153A1 (en) | 2000-07-12 | 2002-01-17 | Utron Inc. | Dynamic consolidation of powders using a pulsed energy source |
US7255105B2 (en) | 2000-10-16 | 2007-08-14 | Pulmonox Technologies Corporation | System for use in administrating therapeutic gas to a patient |
US6668828B1 (en) | 2000-10-16 | 2003-12-30 | Pulmonox Technologies Corporations | System and elements for managing therapeutic gas administration to a spontaneously breathing non-ventilated patient |
SE0004229D0 (sv) | 2000-11-17 | 2000-11-17 | Aga Ab | Inhalation of nitric oxide |
US7335181B2 (en) | 2000-12-26 | 2008-02-26 | Pulmonox Technologies Corporation | Nitric oxide decontamination of the upper respiratory tract |
US6432077B1 (en) | 2000-12-26 | 2002-08-13 | Sensormedics Corporation | Device and method for treatment of surface infections with nitric oxide |
US7122018B2 (en) | 2000-12-26 | 2006-10-17 | Sensormedics Corporation | Device and method for treatment of wounds with nitric oxide |
CA2438005A1 (en) | 2001-02-07 | 2002-08-15 | Synthes (U.S.A.) | Device and method for intraoperative navigation |
RU2183474C1 (ru) | 2001-02-09 | 2002-06-20 | Пекшев Александр Валерьевич | Способ и устройство для формирования no-содержащего газового потока для воздействия на биологический объект |
US6584339B2 (en) | 2001-06-27 | 2003-06-24 | Vanderbilt University | Method and apparatus for collecting and processing physical space data for use while performing image-guided surgery |
RU2199167C1 (ru) | 2001-07-06 | 2003-02-20 | Российский Федеральный Ядерный Центр - Всероссийский Научно-Исследовательский Институт Экспериментальной Физики | Газонаполненный разрядник |
CA2833997C (en) | 2001-09-05 | 2017-09-26 | Geno Llc | Method and apparatus for nitric oxide generation |
US6920876B2 (en) | 2001-12-10 | 2005-07-26 | Pulmonox Technologies Corporation | Device for administration of nitric oxide to horses spontaneously breathing |
US7531133B2 (en) | 2002-09-10 | 2009-05-12 | Pulmonox Technologies Corporation | Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma |
AU2002951984A0 (en) | 2002-10-10 | 2002-10-31 | Compumedics Limited | Sleep quality and auto cpap awakening |
CA2413834A1 (en) | 2002-12-10 | 2004-06-10 | 1017975 Alberta Limited | Nitric oxide gas generator |
US20040226556A1 (en) | 2003-05-13 | 2004-11-18 | Deem Mark E. | Apparatus for treating asthma using neurotoxin |
US20050108813A1 (en) | 2003-07-10 | 2005-05-26 | Cylena Medical Technologies Inc. | Protective apparel spacers and low resistance air flow |
US7485324B2 (en) | 2003-09-29 | 2009-02-03 | Pulmonox Technologies Corporation | Use of exogenous gaseous nitric oxide in the treatment and disinfection of biofilms |
US20050281465A1 (en) | 2004-02-04 | 2005-12-22 | Joel Marquart | Method and apparatus for computer assistance with total hip replacement procedure |
US7051737B2 (en) | 2004-02-05 | 2006-05-30 | The United States Of America As Represented By The Department Of Health And Human Sevices | Mucus shaving apparatus for endotracheal tubes |
WO2005094138A1 (ja) | 2004-03-29 | 2005-10-06 | Mitsubishi Denki Kabushiki Kaisha | プラズマ発生用電源装置 |
JP4320637B2 (ja) | 2004-04-08 | 2009-08-26 | 三菱電機株式会社 | オゾン発生装置およびオゾン発生方法 |
US8518457B2 (en) | 2004-05-11 | 2013-08-27 | Pulmonox Technologies Corporation | Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant |
CN1950120B (zh) | 2004-05-11 | 2010-10-20 | 伟亚医疗森迪斯公司 | 一氧化氮气体的间歇计量 |
US20050263150A1 (en) | 2004-06-01 | 2005-12-01 | Chathampally Yashwant G | Systems and methods for the administration of drugs and medications |
US20060025700A1 (en) | 2004-07-01 | 2006-02-02 | Joel Fallik | Method and apparatus for measuring lung temperature in real time |
WO2006023616A2 (en) | 2004-08-18 | 2006-03-02 | Geno Llc | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
AT500959B1 (de) | 2004-11-09 | 2007-05-15 | Carl M Dr Fleck | Verfahren und filteranordnung zum abscheiden von russpartikeln |
US20060173396A1 (en) | 2004-12-09 | 2006-08-03 | Mehdi Hatamian | Systems and methods for temperature adjustment using bodily fluids as a thermic medium |
JP4997491B2 (ja) | 2005-03-30 | 2012-08-08 | 国立大学法人 熊本大学 | No発生装置 |
US7615931B2 (en) | 2005-05-02 | 2009-11-10 | International Technology Center | Pulsed dielectric barrier discharge |
AU2006248571A1 (en) | 2005-05-19 | 2006-11-23 | E-Pill Pharma, Ltd | Ingestible device for nitric oxide production in tissue |
CN100404083C (zh) * | 2005-08-03 | 2008-07-23 | 华中科技大学 | 呼吸衰竭救治仪的一氧化氮供气*** |
US7832398B2 (en) * | 2005-12-29 | 2010-11-16 | General Elecrtic Company | Arrangement in connection with an anaesthesia/ventilation system for a patient and a gas separation unit for an anaesthesia/ventilation system |
US8790715B2 (en) | 2006-02-16 | 2014-07-29 | Ino Therapeutics Llc | Method and apparatus for generating nitric oxide for medical use |
GB0609400D0 (en) | 2006-05-12 | 2006-06-21 | Intersurgical Ag | Improvements relating to respiratory masks |
WO2008019102A2 (en) | 2006-08-03 | 2008-02-14 | Breathe Technologies, Inc. | Methods and devices for minimally invasive respiratory support |
US7299785B1 (en) | 2006-08-30 | 2007-11-27 | Bruce D. Browne | Embedded igniter system for internal combustion engines |
US20080078382A1 (en) * | 2006-09-20 | 2008-04-03 | Lemahieu Edward | Methods and Systems of Delivering Medication Via Inhalation |
US8079998B2 (en) | 2006-10-20 | 2011-12-20 | Pulmonox Technologies Corporation | Methods and devices for the delivery of therapeutic gases including nitric oxide |
US8020552B2 (en) | 2007-02-26 | 2011-09-20 | Microtek Medical, Inc. | Helmets and methods of making and using the same |
ZA200905520B (en) | 2007-03-09 | 2010-10-27 | Strata Products Worldwide Llc | Apparatus, system and method for cleaning air |
US7589473B2 (en) | 2007-08-06 | 2009-09-15 | Plasma Surgical Investments, Ltd. | Pulsed plasma device and method for generating pulsed plasma |
WO2009018837A1 (en) | 2007-08-06 | 2009-02-12 | Plasma Surgical Investments Limited | Pulsed plasma device and method for generating pulsed plasma |
US9649467B2 (en) | 2008-01-31 | 2017-05-16 | Syk Technologies, Llc | Nitric oxide reactor and distributor apparatus and method |
JP4576464B2 (ja) | 2008-08-05 | 2010-11-10 | 本田技研工業株式会社 | 排ガス浄化装置の劣化判定装置 |
US8539953B2 (en) | 2008-11-19 | 2013-09-24 | John E. Moenning, Jr. | Combination anesthesia and scavenger surgical mask |
WO2010088191A1 (en) | 2009-01-27 | 2010-08-05 | Teleflex Medical Incorporated | Sputum dissolving suctioning solution for endotracheal and tracheostomy tubes |
US9511240B2 (en) | 2009-03-16 | 2016-12-06 | Drexel University | Apparatus for atmospheric pressure pin-to-hole spark discharge and uses thereof |
TW201034710A (en) | 2009-03-31 | 2010-10-01 | Top Vision Medical Equipment Consultant Co Ltd | Gas supply device capable of sensing and displaying concentration of suspended particles |
US8151791B2 (en) | 2009-04-29 | 2012-04-10 | Lifeserve Innovations, Llc | Methods and devices for performing an emergency or non-emergency tracheotomy |
CA3130908A1 (en) | 2009-06-30 | 2010-12-30 | Mallinckrodt Hospital Products IP Limited | Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension |
US8416552B2 (en) | 2009-10-23 | 2013-04-09 | Illinois Tool Works Inc. | Self-balancing ionized gas streams |
DE102009053067A1 (de) | 2009-11-13 | 2011-05-19 | Willy Rüsch GmbH | Trachealtubus mit Temperatursensor |
WO2011077327A2 (en) * | 2009-12-23 | 2011-06-30 | Koninklijke Philips Electronics N.V. | Method for generating nitric oxide |
DE202011101554U1 (de) | 2010-08-11 | 2011-11-16 | Sls Medical Technology Corp., Ltd. | Beatmungsgerät zum Identifizieren der Reinheit/Trübung eines Filters |
US20140031668A1 (en) | 2010-09-08 | 2014-01-30 | Disruptive Navigational Technologies, Llc | Surgical and Medical Instrument Tracking Using a Depth-Sensing Device |
US8573209B2 (en) | 2011-01-06 | 2013-11-05 | Ino Therapeutics Llc | Gas delivery device and system |
WO2012155213A1 (en) | 2011-05-18 | 2012-11-22 | Ulco Medical Pty Ltd | Soda lime cartridge |
CN103619273B (zh) | 2011-06-22 | 2016-05-25 | 新特斯有限责任公司 | 包括位置跟踪***的用于操纵骨的组件 |
CA2850935C (en) | 2011-10-03 | 2018-08-07 | Nitric Generation Technologies Llc | Apparatus and method for generating nitric oxide in controlled and accurate amounts |
JP2014532523A (ja) | 2011-11-07 | 2014-12-08 | アイ・エヌ・オー セラピューティクス エル・エル・シーINO Therapeutics LLC | 一酸化窒素送出を監視する装置および方法 |
US8693730B2 (en) | 2011-11-15 | 2014-04-08 | Macdonald Dettwiler & Associates Inc. | Method of real-time tracking of moving/flexible surfaces |
EP2782869A1 (de) | 2011-11-22 | 2014-10-01 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren und vorrichtung zur erzeugung eines nicht-thermischen plasmas mit vorherbestimmter ozonkonzentration |
WO2013132499A1 (en) | 2012-03-07 | 2013-09-12 | Advanced Inhilation Therapies (Ait) Ltd. | Inhalation of nitric oxide for treating respiratory diseases |
CA2874999A1 (en) | 2012-05-30 | 2013-12-05 | David Bruce Crosbie | Nitric oxide generator and inhaler |
US9067788B1 (en) | 2012-11-01 | 2015-06-30 | Rick B. Spielman | Apparatus for highly efficient cold-plasma ozone production |
WO2014071350A1 (en) * | 2012-11-05 | 2014-05-08 | Geno Llc | Dual platform system for the delivery of nitric oxide |
CN104955508A (zh) | 2012-11-28 | 2015-09-30 | 艾尼科提恩科技公司 | 用于化合物递送的方法和设备 |
DK3636306T3 (da) | 2012-12-04 | 2024-04-29 | Mallinckrodt Hospital Products Ip Ltd | Kanyle til minimering af fortynding af dosering under afgivelse af nitrogenmonoxid |
US9795756B2 (en) | 2012-12-04 | 2017-10-24 | Mallinckrodt Hospital Products IP Limited | Cannula for minimizing dilution of dosing during nitric oxide delivery |
KR101308788B1 (ko) * | 2012-12-13 | 2013-09-16 | 운해이엔씨(주) | 무균 및 무취의 산화질소 발생장치 |
WO2014136111A2 (en) | 2013-03-07 | 2014-09-12 | Advanced Inhalation Therapies (Ait) Ltd. | Inhalation of nitric oxide for treating respiratory diseases |
AU2014228152B2 (en) * | 2013-03-15 | 2018-07-05 | The General Hospital Corporation | Synthesis of nitric oxide gas for inhalation |
JP6186146B2 (ja) | 2013-03-15 | 2017-08-23 | 株式会社Uacj | 熱交換器 |
US9522247B2 (en) | 2013-06-28 | 2016-12-20 | L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude | Method of treating a patient having pulmonary hypertension by long term NO therapy |
EP3033132B1 (en) | 2013-08-15 | 2021-01-06 | Intuitive Surgical Operations, Inc. | Graphical user interface for catheter positioning and insertion |
WO2015037002A2 (en) | 2013-09-11 | 2015-03-19 | Advanced Inhalation Therapies (Ait) Ltd. | System for nitric oxide inhalation |
US20150072023A1 (en) | 2013-09-11 | 2015-03-12 | Advanced Inhalation Therapies (Ait) Ltd. | Inhalation of nitric oxide for treating respiratory diseases |
TW201521805A (zh) | 2013-10-31 | 2015-06-16 | Advanced Plasma Therapies Inc | 使用電漿狀態之氧化氮來治療醫療狀況與疾病之方法 |
CN106662559B (zh) | 2014-02-19 | 2019-09-27 | 马林克罗特医疗产品知识产权公司 | 用于补偿暴露于一氧化氮的电化学气体传感器的长期灵敏度漂移的方法 |
EP3197464A4 (en) | 2014-08-25 | 2018-01-17 | Advanced Inhalation Therapies (AIT) Ltd. | Treatment of inflammation, respiratory tract infections and cystic fibrosis |
-
2015
- 2015-10-20 AU AU2015336055A patent/AU2015336055B2/en active Active
- 2015-10-20 CN CN202310076877.8A patent/CN116177503A/zh active Pending
- 2015-10-20 EP EP15853515.3A patent/EP3209359B1/en active Active
- 2015-10-20 US US15/520,137 patent/US11497878B2/en active Active
- 2015-10-20 KR KR1020177013677A patent/KR20170072293A/ko not_active Application Discontinuation
- 2015-10-20 CN CN201580056811.6A patent/CN107073239A/zh active Pending
- 2015-10-20 WO PCT/US2015/056443 patent/WO2016064863A1/en active Application Filing
- 2015-10-20 EP EP20183011.4A patent/EP3753597A1/en active Pending
- 2015-10-20 RU RU2017113542A patent/RU2730960C2/ru active
- 2015-10-20 JP JP2017539531A patent/JP6947633B2/ja active Active
- 2015-10-20 BR BR112017007841-4A patent/BR112017007841B1/pt active IP Right Grant
- 2015-10-20 ES ES15853515T patent/ES2822215T3/es active Active
- 2015-10-20 CA CA2963874A patent/CA2963874C/en active Active
- 2015-10-20 MX MX2017004796A patent/MX2017004796A/es unknown
-
2020
- 2020-10-16 AU AU2020256426A patent/AU2020256426B2/en active Active
-
2021
- 2021-09-15 JP JP2021149832A patent/JP7234319B2/ja active Active
-
2022
- 2022-10-10 US US17/963,044 patent/US20230140163A1/en active Pending
-
2023
- 2023-02-21 JP JP2023024982A patent/JP2023059931A/ja active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010031230A1 (en) | 1998-05-27 | 2001-10-18 | Siemens Aktiengesellschaft | Apparatus for plasma-chemical production of nitrogen monoxide |
JP2004065636A (ja) | 2002-08-07 | 2004-03-04 | Osaka Industrial Promotion Organization | 可搬型医療用一酸化窒素発生装置及び可搬型医療用一酸化窒素吸入装置 |
WO2014144151A1 (en) | 2013-03-15 | 2014-09-18 | The General Hospital Corporation | Inspiratory synthesis of nitric oxide |
Also Published As
Publication number | Publication date |
---|---|
RU2730960C2 (ru) | 2020-08-26 |
CN116177503A (zh) | 2023-05-30 |
WO2016064863A8 (en) | 2017-04-27 |
US11497878B2 (en) | 2022-11-15 |
EP3209359B1 (en) | 2020-07-01 |
MX2017004796A (es) | 2017-07-27 |
US20180296790A1 (en) | 2018-10-18 |
RU2017113542A3 (ja) | 2019-04-02 |
WO2016064863A1 (en) | 2016-04-28 |
EP3753597A1 (en) | 2020-12-23 |
RU2017113542A (ru) | 2018-11-22 |
JP2017531539A (ja) | 2017-10-26 |
CA2963874A1 (en) | 2016-04-28 |
BR112017007841B1 (pt) | 2022-11-08 |
AU2015336055B2 (en) | 2020-07-16 |
AU2020256426B2 (en) | 2022-07-07 |
US20230140163A1 (en) | 2023-05-04 |
JP2022000177A (ja) | 2022-01-04 |
BR112017007841A2 (pt) | 2017-12-26 |
ES2822215T3 (es) | 2021-04-29 |
CN107073239A (zh) | 2017-08-18 |
EP3209359A4 (en) | 2018-05-30 |
JP2023059931A (ja) | 2023-04-27 |
JP6947633B2 (ja) | 2021-10-13 |
AU2020256426A1 (en) | 2020-11-12 |
KR20170072293A (ko) | 2017-06-26 |
AU2015336055A1 (en) | 2017-04-20 |
EP3209359A1 (en) | 2017-08-30 |
CA2963874C (en) | 2023-10-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP7234319B2 (ja) | 一酸化窒素の合成のためのシステム及び方法 | |
US12011544B2 (en) | Inspiratory synthesis of nitric oxide | |
US11827989B2 (en) | Systems and methods for preventing and treating infections with nitric oxide | |
CN109310842B (zh) | 用于电等离子体合成一氧化氮的输送***和方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20210915 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20220531 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20220607 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20220905 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20221104 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20221207 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20230124 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20230222 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7234319 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |