JP6723979B2 - しわ改善剤 - Google Patents
しわ改善剤 Download PDFInfo
- Publication number
- JP6723979B2 JP6723979B2 JP2017240674A JP2017240674A JP6723979B2 JP 6723979 B2 JP6723979 B2 JP 6723979B2 JP 2017240674 A JP2017240674 A JP 2017240674A JP 2017240674 A JP2017240674 A JP 2017240674A JP 6723979 B2 JP6723979 B2 JP 6723979B2
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- JP
- Japan
- Prior art keywords
- wrinkle
- dipotassium glycyrrhizinate
- skin
- extract
- improving agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000037303 wrinkles Effects 0.000 title claims description 36
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 claims description 30
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- 230000008733 trauma Effects 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 239000002349 well water Substances 0.000 description 1
- 235000020681 well water Nutrition 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Landscapes
- Cosmetics (AREA)
Description
本実施形態のしわ改善剤は、グリチルリチン酸ジカリウムを有効成分とするものである。
また、飲食品としては、その区分に制限はなく、経口的に摂取される一般食品、健康食品(機能性飲食品)、保健機能食品(特定保健用食品,栄養機能食品)等を幅広く含むものである。
なお、本実施形態のしわ改善剤は、ヒトに対して好適に適用されるものであるが、それぞれの作用効果が奏される限り、ヒト以外の動物(例えば、マウス,ラット,ハムスター,イヌ,ネコ,ウシ,ブタ,サル等)に対して適用することもできる。
下記組成に従い、化粧水を常法により製造した。
グリチルリチン酸ジカリウム 0.5質量%
POE・POPデシルテトラデシルエーテル 0.10質量%
キサンタンガム 0.50質量%
クエン酸 0.04質量%
クエン酸ナトリウム 0.16質量%
エデト酸二ナトリウム 0.03質量%
フェノキシエタノール 0.30質量%
パラオキシ安息香酸エステル 0.15質量%
精製水 残部(全量を100質量%とする)
グリチルリチン酸ジカリウムを配合しなかった以外は配合例1と同様にして、化粧水を製造した。
上記のようにして得られた配合例1および比較配合例1の化粧水を用い、以下のようにしてしわ改善作用を試験した。
結果を表1に示す。
また、配合例1の塗布部位と比較配合例1の塗布部位とを比較すると、試験開始日から試験開始4週後の変化量において、配合例1の塗布部位(−0.5%±1.2%)と比較配合例1の塗布部位(0.3%±1.5%)との間に有意差(p=0.012)が認められた。
そのため、配合例1(グリチルリチン酸ジカリウム配合)塗布群では、試験期間前後の比較において、さらには比較配合例1塗布群との比較において、目尻のしわが改善されているものと認められた。
下記組成に従い、乳液を常法により製造した。
グリチルリチン酸ジカリウム 0.01g
ホホバオイル 4.00g
1,3−ブチレングリコール 3.00g
アルブチン 3.00g
ポリオキシエチレンセチルエーテル(20E.O.) 2.50g
オリーブオイル 2.00g
スクワラン 2.00g
セタノール 2.00g
モノステアリン酸グリセリル 2.00g
オレイン酸ポリオキシエチレンソルビタン(20E.O.) 2.00g
パラオキシ安息香酸メチル 0.15g
黄杞エキス 0.10g
イチョウ葉エキス 0.10g
コンキオリン 0.10g
オウバクエキス 0.10g
カミツレエキス 0.10g
香料 0.05g
精製水 残部(全量を100gとする)
下記組成のクリームを常法により製造した。
グリチルリチン酸ジカリウム 1.0g
クジンエキス 0.1g
オウゴンエキス 0.1g
流動パラフィン 5.0g
サラシミツロウ 4.0g
スクワラン 10.0g
セタノール 3.0g
ラノリン 2.0g
ステアリン酸 1.0g
オレイン酸ポリオキシエチレンソルビタン(20E.O.) 1.5g
モノステアリン酸グリセリル 3.0g
油溶性甘草エキス 0.1g
1,3−ブチレングリコール 6.0g
パラオキシ安息香酸メチル 1.5g
香料 0.1g
精製水 残部(全量を100gとする)
下記組成の美容液を常法により製造した。
グリチルリチン酸ジカリウム 0.1g
カミツレエキス 0.1g
ニンジンエキス 0.1g
キサンタンガム 0.3g
ヒドロキシエチルセルロース 0.1g
カルボキシビニルポリマー 0.1g
1,3−ブチレングリコール 4.0g
グリセリン 2.0g
水酸化カリウム 0.25g
香料 0.01g
防腐剤(パラオキシ安息香酸メチル) 0.15g
エタノール 2.0g
精製水 残部(全量を100gとする)
Claims (1)
- グリチルリチン酸ジカリウムを有効成分とするしわ改善用皮膚化粧料であって、
前記グリチルリチン酸ジカリウムの配合量が0.1〜1質量%であることを特徴とするしわ改善用皮膚化粧料(クレアチンリン酸または酸化的CoAもしくはその塩が配合されたものを除く)。
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JP2017240674A JP6723979B2 (ja) | 2017-12-15 | 2017-12-15 | しわ改善剤 |
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JP2020017402A Division JP2020073585A (ja) | 2020-02-04 | 2020-02-04 | しわ改善剤 |
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JP6723979B2 true JP6723979B2 (ja) | 2020-07-15 |
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WO2023022011A1 (ja) * | 2021-08-17 | 2023-02-23 | 株式会社 資生堂 | 美容方法 |
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JP3008161B2 (ja) * | 1995-07-10 | 2000-02-14 | 株式会社ローズメイ | 化粧水 |
JP2001039853A (ja) * | 1999-07-30 | 2001-02-13 | Lion Corp | 皮膚外用剤 |
JP2008094813A (ja) * | 2006-10-16 | 2008-04-24 | Naris Cosmetics Co Ltd | 抗老化皮膚組成物 |
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