JP6712976B2 - 皮膚引締めのためのデバイスおよび方法 - Google Patents
皮膚引締めのためのデバイスおよび方法 Download PDFInfo
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Description
本願は、a)米国仮特許出願第61/448,809号(2011年3月3日出願)、b)米国仮特許出願第61/476,163号(2011年4月15日出願)、およびc)米国仮特許出願第61/605,717号(2012年3月1日出願)の米国特許法第119条第(e)項の利益を主張し、これらの出願のすべては、その全体が参照することによって本明細書に援用される。本願はまた、米国特許出願第11/888,978号(2007年8月3日出願)、米国特許出願第12/854,859号(2010年8月11日出願)、および米国特許出願第13/345,524号(2012年1月6日出願)と関連し、これらの出願のすべては、その全体が参照することによって本明細書に援用される。
例えば、本願発明は以下の項目を提供する。
(項目1)
皮膚治療システムであって、該システムは、
少なくとも0.4の歪において、少なくとも0.1ニュートンの1ミリメートル幅当たりの負荷を有する弾性平面構造と、
該弾性平面構造に連結され、所定の歪を超えて該弾性平面構造が歪むことに抵抗するように構成された歪制限器と
を備える、皮膚治療システム。
(項目2)
前記歪制限器は、該歪制限器の第1の端部における第1のハンドルと、該歪制限器の第2の端部における第2のハンドルとを備える、項目1に記載の皮膚治療システム。
(項目3)
少なくとも2つの細長い歪制限構造を備える、項目2に記載の皮膚治療システム。
(項目4)
前記第1のハンドルは、前記少なくとも2つの細長い歪制限構造の第1の端部の間で前記弾性平面構造に隣接して連結される、項目3に記載の皮膚治療システム。
(項目5)
前記第1のハンドルは、前記少なくとも2つの細長い歪制限構造の第1の端部の間で前記弾性平面構造に隣接しないで連結される、項目3に記載の皮膚治療システム。
(項目6)
前記第2のハンドルは、前記少なくとも2つの細長い歪制限構造の第2の端部の間で前記弾性平面構造に隣接して連結される、項目4に記載の皮膚治療システム。
(項目7)
前記所定の歪は、少なくとも0.2である、項目1に記載の皮膚治療システム。
(項目8)
前記所定の歪は、少なくとも0.4である、項目7に記載の皮膚治療システム。
(項目9)
前記歪制限器は、前記弾性平面構造に解放可能に連結される、項目1に記載の皮膚治療システム。
(項目10)
前記歪制限器は、接着剤を使用して前記弾性平面構造に接着される、項目9に記載の皮膚治療システム。
(項目11)
前記接着剤は、ある力レベルに対する剪断抵抗を備え、該剪断抵抗は、該力レベルに対するT型剥離抵抗よりも大きい、項目10に記載の皮膚治療システム。
(項目12)
前記第1のハンドルおよび前記第2のハンドルは、前記弾性平面構造と比べて実質的に非弾性の材料を含む、項目2に記載の皮膚治療システム。
(項目13)
前記実質的に非弾性の材料は、半剛性または剛性の材料である、項目12に記載の皮膚治療システム。
(項目14)
前記歪制限器は、少なくとも1つの可撓性で非弾性の細長い要素を備える、項目9に記載の皮膚治療システム。
(項目15)
前記弾性平面構造は、歪んでいない構成を備え、該歪んでいない構成において、前記歪制限器の第1の取付領域と該歪制限器の第2の取付領域との間の距離は、該第1の取付領域と該第2の取付領域との間の該歪制限器の長さよりも短い、項目14に記載の皮膚治療システム。
(項目16)
前記弾性平面構造は、前記所定の歪における歪んだ構成を備え、前記歪制限器の前記第1の取付領域と該歪制限器の前記第2の取付領域との間の前記距離は、該第1の取付領域と該第2の取付領域との間の該歪制限器の長さに実質的に等しい、項目15に記載の皮膚治療システム。
(項目17)
前記弾性平面構造は、歪んでいない構成を備え、該歪んでいない構成において、前記歪制限器の第1の取付領域と該歪制限器の第2の取付領域との間の第1の距離は、該歪制限器の長さよりも小さい、項目1に記載の皮膚治療システム。
(項目18)
前記歪制限器は、少なくとも3つの二つ折を有する折畳み板を備える、項目1に記載の皮膚治療システム。
(項目19)
前記歪制限器は、ラチェットおよび歯止め機構を備える、項目1に記載の皮膚治療システム。
(項目20)
前記歪制限器は、複数の所定の歪を超えて前記弾性平面構造が歪むことに抵抗するように選択的に構成されている、項目1に記載の皮膚治療システム。
(項目21)
前記複数の所定の歪の各々は、前記歪制限器上に図形印を備える、項目20に記載の皮膚治療システム。
(項目22)
皮膚治療システムであって、該システムは、
引張軸を備える弾性平面構造と、
該弾性平面構造に連結され、所定の歪を超えて該弾性平面構造が歪むことに抵抗するように構成された歪制限器であって、該歪制限器の第1の端部の該弾性平面構造への取付は、該引張軸に対して直角である該弾性平面構造の寸法にわたって隣接する、歪制限器と
を備える、皮膚治療システム。
(項目23)
前記弾性平面構造は、少なくとも0.4の歪において、少なくとも0.1ニュートンの1ミリメートル幅当たりの負荷を有する構造を備える、項目22に記載の皮膚治療システム。
(項目24)
前記歪制限器は、該歪制限器の第1の端部における第1のハンドルと、該歪制限器の第2の端部における第2のハンドルとを備える、項目22に記載の皮膚治療システム。
(項目25)
前記歪制限器は、少なくとも2つの細長い要素を備える、項目24に記載の皮膚治療システム。
(項目26)
前記第1のハンドルは、前記少なくとも2つの細長い要素の第1の端部の間で前記弾性平面構造に隣接して連結される、項目25に記載の皮膚治療システム。
(項目27)
前記第1のハンドルは、前記少なくとも2つの細長い要素の第1の端部の間で前記弾性平面構造に隣接しないで連結される、項目26に記載の皮膚治療システム。
(項目28)
前記第2のハンドルは、前記少なくとも2つの細長い要素の第2の端部の間で前記弾性平面構造に隣接して連結される、項目24に記載の皮膚治療システム。
(項目29)
前記所定の歪は、少なくとも0.2である、項目22に記載の皮膚治療システム。
(項目30)
前記所定の歪は、少なくとも0.4である、項目29に記載の皮膚治療システム。
(項目31)
前記歪制限器は、前記弾性平面構造に解放可能に連結される、項目22に記載の皮膚治療システム。
(項目32)
前記歪制限器は、接着剤を使用して前記弾性平面構造に接着される、項目31に記載の皮膚治療システム。
(項目33)
前記接着剤は、ある力レベルに対する剪断抵抗を備え、該剪断抵抗は、該力レベルに対するT型剥離抵抗よりも大きい、項目32に記載の皮膚治療システム。
(項目34)
前記第1のハンドルおよび前記第2のハンドルは、前記弾性平面構造と比べて実質的に非弾性の材料を含む、項目24に記載の皮膚治療システム。
(項目35)
前記実質的に非弾性の材料は、半剛性または剛性の材料である、項目34に記載の皮膚治療システム。
(項目36)
前記歪制限器は、少なくとも1つの可撓性で非弾性の細長い要素を備える、項目31に記載の皮膚治療システム。
(項目37)
前記弾性平面構造は、歪んでいない構成を備え、該歪んでいない構成において、前記歪制限器の第1の取付領域と該歪制限器の第2の取付領域との間の距離は、該第1の取付領域と該第2の取付領域との間の該歪制限器の長さよりも短い、項目22に記載の皮膚治療システム。
(項目38)
前記弾性平面構造は、前記所定の歪における歪んだ構成を備え、前記歪制限器の前記第1の取付領域と該歪制限器の第2の取付領域との間の前記距離は、該第1の取付領域と該第2の取付領域との間の該歪制限器の長さに実質的に等しい、項目37に記載の皮膚治療システム。
(項目39)
前記弾性平面構造は、歪んでいない構成を備え、該歪んでいない構成において、前記少なくとも1つの歪制限器の第1の取付領域と該少なくとも1つの歪制限器の第2の取付領域との間の第1の距離は、該歪制限器の長さよりも短い、項目22に記載の皮膚治療システム。
(項目40)
前記歪制限器は、少なくとも3つの二つ折を有する折畳み板を備える、項目22に記載の皮膚治療システム。
(項目41)
前記歪制限器は、ラチェットおよび歯止め機構を備える、項目22に記載の皮膚治療システム。
(項目42)
前記歪制限器は、複数の所定の歪を超えて前記弾性平面構造が歪むことに抵抗するように選択的に構成されている、項目22に記載の皮膚治療システム。
(項目43)
前記複数の所定の歪の各々は、前記歪制限器上に図形印を備える、項目42に記載の皮膚治療システム。
(項目44)
皮膚治療デバイスであって、該デバイスは、
所定の歪レベルまで事前に伸長させられた弾性材料を含む第1の層と、
該第1の層に連結され、ブレースを備える第2の層であって、該第2の層は、該デバイスが対象の皮膚層に取り付けられている間、該第1の層を該所定の歪レベルに維持するように構成され、該第2の層は、少なくとも1つの第2の層開口部を備え、該少なくとも1つの第2の層開口部は、それを通した皮膚の治療に対して設置可能である、第2の層と、
該少なくとも1つの第2の層開口部を通した治療中に該デバイスを対象の皮膚に固定するように構成された固定要素と
を備える、皮膚治療デバイス。
(項目45)
前記第1の層は、弾性材料を通る少なくとも1つの該弾性材料の開口部を備え、該弾性材料の開口部は、前記第2の層の前記少なくとも1つの開口部と整列させられて、該整列した開口部を通して治療するように構成されている、項目44に記載の皮膚治療デバイス。
(項目46)
前記ブレースは、噛合要素をさらに備え、該噛合要素は、歪んだ構成にある前記第1の層を該ブレース上に固定するように構成されている、項目44に記載の皮膚治療デバイス。
(項目47)
前記ブレースは、剛性である、項目44に記載の皮膚治療デバイス。
(項目48)
前記ブレースは、複数のセグメントを備え、該複数のセグメントは、該複数のセグメントのうちの別のセグメントに対して屈曲可能であることにより、該ブレースの可変の輪郭を提供する、項目44に記載の皮膚治療デバイス。
(項目49)
前記ブレースは、複数の方向に屈曲可能であるように構成されている、項目48に記載の皮膚治療デバイス。
(項目50)
前記複数のセグメントの各々は、複数の方向に屈曲させられるように構成されている、項目48に記載の皮膚治療デバイス。
(項目51)
前記第2の層は、開口部のパターンを有するマスクを備える、項目44に記載の皮膚治療デバイス。
(項目52)
前記開口部のパターンは、治療パターンを備える、項目51に記載の皮膚治療デバイス。
(項目53)
接続要素をさらに備える、該接続要素は、前記デバイスをエネルギー放出皮膚治療デバイスに接続するように構成されている、項目44に記載の皮膚治療デバイス。
(項目54)
各第2の層開口部は、少なくとも1つの個別治療ゾーンに対応する、項目44に記載の皮膚治療デバイス。
(項目55)
前記第2の層は、治療が少なくとも1つの第2の層開口部を通して提供された後に、前記第1の層から除去可能である、項目44に記載の皮膚治療デバイス。
(項目56)
多層弾性手当て用品であって、該手当て用品は、
複数の弾性層を備え、各層は、該複数の弾性層のうちの別の層に除去可能に連結され、該複数の弾性層は、基層であって、該基層は、該基層の皮膚接着側面に皮膚接着剤層を有する、基層と、少なくとも1つの付加的な層とを備える、多層弾性手当て用品。
(項目57)
各前記少なくとも1つの付加的な弾性層は、前記手当て用品が歪まされ、対象の皮膚に接着され、それにより、前記基層を介して該皮膚にかけられた応力を選択的に変化させた後に、該基層から除去可能である、項目56に記載の多層弾性手当て用品。
(項目58)
対象を治療する方法であって、該方法は、対象の皮膚に複数の損傷を作成することと、該対象の皮膚の該損傷を覆って手当て用品を配置することとを含む、対象を治療する方法。
(項目59)
対象を治療する方法であって、該方法は、皮膚領域を覆って手当て用品を配置することと、該手当て用品を通して該皮膚領域の中に損傷を作成することとを含む、対象を治療する方法。
(項目60)
前記皮膚領域の中に損傷を作成することは、エネルギーベースのモダリティを使用して行われる、項目59に記載の方法。
(項目61)
前記手当て用品は、前記エネルギーベースのモダリティを選択的にブロックするように構成されたマスク領域と、該エネルギーベースのモダリティからのエネルギーが該手当て用品を通過することを選択的に可能にするように構成された治療領域とを備える、項目60に記載の方法。
(項目62)
前記治療領域は、遮断されない構造を備え、該遮断されない構造は、エネルギーが該遮断されない構造を通過することを選択的に可能にするように構成されている、項目61に記載の方法。
(項目63)
前記遮断されない構造は、光学的に透明な構造である、項目62に記載の方法。
(項目64)
治療デバイスを前記手当て用品上に位置する印に整列させることをさらに含む、項目59に記載の方法。
(項目65)
治療デバイスを前記手当て用品の既存の開口部に整列させることをさらに含む、項目59に記載の方法。
(項目66)
前記既存の開口部は、前記手当て用品の既存の潜在的開口部である、項目65に記載の方法。
(項目67)
前記既存の潜在的開口部は、スリットを備える、項目66に記載の方法。
(項目68)
治療デバイスを使用して、前記手当て用品に複数の開口部を作成することをさらに含む、項目59に記載の方法。
(項目69)
対象を治療する方法であって、該方法は、弾性の手当て用品において歪を維持することと、該歪んだ手当て用品を対象の皮膚を覆って配置することと、該手当て用品を通して該対象の該皮膚に少なくとも1つの損傷を作成することと、次いで、該手当て用品からの圧縮力が該対象の該皮膚に印加されるように、該手当て用品を解放することとを含む、対象を治療する方法。
Claims (11)
- 皮膚引締めシステムであって、
皮膚損傷のパターンを作成するように構成された治療デバイスと;
該皮膚損傷のパターンを圧迫するように構成された、事前に歪まされた弾性手当て用品であって、該治療デバイスに連結された、手当て用品と
を備える、皮膚引締めシステム。 - 前記治療デバイスが機械的治療デバイスである、請求項1に記載のシステム。
- 前記治療デバイスがレーザ治療デバイスである、請求項1に記載のシステム。
- 前記治療デバイスが超音波治療デバイスである、請求項1に記載のシステム。
- 前記治療デバイスが治療要素の配列を備える、請求項1に記載のシステム。
- 前記治療要素の配列が、2〜20の治療要素を含む、請求項5に記載のシステム。
- 前記治療要素の配列が、機械的治療要素である、請求項5に記載のシステム。
- 前記手当て用品が除去可能なパターン化されたマスクをさらに備える、請求項1に記載のシステム。
- 前記治療デバイスが、楕円形の皮膚損傷を作成するように構成される、請求項1に記載のシステム。
- 前記治療デバイスが、スリット形状の皮膚損傷を作成するように構成される、請求項1に記載のシステム。
- 前記治療デバイスが、二重テーパ状の皮膚損傷を作成するように構成される、請求項1に記載のシステム。
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BRPI0715075B1 (pt) | 2006-08-03 | 2021-11-30 | The Board Of Trustees Of The Leland Stanford Junior University | Bandagem para melhorar a formação de uma cicatriz ou queloide em um local de ferimento |
CA2578927C (en) | 2007-02-19 | 2011-09-27 | Ray Arbesman | Precut adhesive body support articles and support system |
US9241835B2 (en) | 2007-08-03 | 2016-01-26 | Neodyne Biosciences, Inc. | Wound or skin treatment devices with variable edge geometries |
US9358009B2 (en) | 2007-08-03 | 2016-06-07 | Neodyne Biosciences, Inc. | Skin straining devices and methods |
US9668922B2 (en) | 2007-08-03 | 2017-06-06 | Neodyne Biosciences, Inc. | Wound or skin treatment devices with variable edge geometries |
US8592640B2 (en) | 2009-08-11 | 2013-11-26 | Neodyne Biosciences, Inc. | Devices and methods for dressing applicators |
EP2307095B1 (en) | 2008-06-29 | 2020-06-03 | Venus Concept Ltd | An esthetic apparatus useful for increasing skin rejuvenation |
US9981143B2 (en) | 2008-06-29 | 2018-05-29 | Venus Concept Ltd. | Esthetic apparatus useful for increasing skin rejuvenation and methods thereof |
US10159825B2 (en) | 2009-09-17 | 2018-12-25 | Zipline Medical, Inc. | Rapid closing surgical closure device |
US8900181B2 (en) | 2009-12-18 | 2014-12-02 | Srgi Holdings, Llc | Skin treatment and drug delivery device |
CN103002844B (zh) | 2010-06-14 | 2016-08-31 | 奇普林医药公司 | 用于抑制疤痕形成的方法和装置 |
US10736653B2 (en) | 2013-12-06 | 2020-08-11 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US10716924B2 (en) | 2010-12-17 | 2020-07-21 | Srgi Holdings, Llc | Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal |
US10702684B2 (en) | 2010-12-17 | 2020-07-07 | Srgi Holdings, Llc | Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal |
US10695546B2 (en) | 2010-12-17 | 2020-06-30 | Srgi Holdings, Llc | Systems, devices and methods for fractional resection, fractional skin grafting, fractional scar reduction and fractional tattoo removal |
US11103275B2 (en) | 2010-12-17 | 2021-08-31 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US11000310B2 (en) | 2010-12-17 | 2021-05-11 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US10342574B2 (en) | 2010-12-17 | 2019-07-09 | Srgi Holdings, Llc | Pixel array medical devices and methods |
US10772658B2 (en) | 2010-12-17 | 2020-09-15 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US10368904B2 (en) | 2013-12-06 | 2019-08-06 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US11278309B2 (en) | 2010-12-17 | 2022-03-22 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
KR101944844B1 (ko) | 2011-01-07 | 2019-02-01 | 네오다인 바이오사이언시스, 인코포레이티드 | 상처 또는 피부 치료 장치 및 방법 |
DK2667801T3 (en) | 2011-01-28 | 2019-04-08 | Massachusetts Gen Hospital | Method and device for discontinuous dermabrasion |
AU2012211122B2 (en) | 2011-01-28 | 2016-07-07 | The General Hospital Corporation | Method and apparatus for skin resurfacing |
EP2667805B1 (en) | 2011-01-28 | 2023-04-05 | The General Hospital Corporation | Apparatus and method for tissue biopsy |
KR102185635B1 (ko) * | 2011-03-03 | 2020-12-03 | 네오다인 바이오사이언시스, 인코포레이티드 | 피부 타이트닝을 위한 장치 및 방법 |
PT2734249T (pt) | 2011-07-21 | 2018-11-13 | Massachusetts Gen Hospital | Aparelho para danificar e remover gordura |
US10123801B2 (en) | 2011-11-01 | 2018-11-13 | Zipline Medical, Inc. | Means to prevent wound dressings from adhering to closure device |
US10123800B2 (en) | 2011-11-01 | 2018-11-13 | Zipline Medical, Inc. | Surgical incision and closure apparatus with integrated force distribution |
US9561034B2 (en) | 2011-11-01 | 2017-02-07 | Zipline Medical, Inc. | Surgical incision and closure apparatus |
US10561359B2 (en) | 2011-12-02 | 2020-02-18 | Neodyne Biosciences, Inc. | Elastic devices, methods, systems and kits for selecting skin treatment devices |
US9827447B1 (en) * | 2011-12-02 | 2017-11-28 | Neodyne Biosciences, Inc. | Devices, methods, systems and kits for selecting skin treatment devices |
US10213350B2 (en) | 2012-02-08 | 2019-02-26 | Neodyne Biosciences, Inc. | Radially tensioned wound or skin treatment devices and methods |
US20150173991A1 (en) * | 2012-07-06 | 2015-06-25 | The General Hospital Corporation | Method and apparatus for dermatological treatment |
EP2872216B1 (en) * | 2012-07-06 | 2022-02-23 | The General Hospital Corporation | Method and apparatus for dermatological treatment |
US10888375B2 (en) * | 2012-07-06 | 2021-01-12 | The General Hospital Corporation | Method and apparatus for dermatological treatment |
CN205411238U (zh) * | 2012-10-21 | 2016-08-03 | 艾恩梅德有限公司 | 用于通过等离子体焊改善组织治疗的膜及包括其的套件 |
CA2894280C (en) | 2012-12-06 | 2018-07-31 | Srgi Holdings Llc | Pixel array medical devices and methods |
AU2014219240B2 (en) * | 2013-02-20 | 2018-12-20 | Cytrellis Biosystems, Inc. | Methods and devices for skin tightening |
US20140276354A1 (en) | 2013-03-14 | 2014-09-18 | Klox Technologies Inc. | Biophotonic materials and uses thereof |
EP2968017B1 (en) * | 2013-03-15 | 2019-04-24 | Neodyne Biosciences, Inc. | Wound or skin treatment devices with variable edge geometries |
EP2991600B1 (en) | 2013-05-03 | 2018-08-01 | Cytrellis Biosystems, Inc. | Microclosures and related methods for skin treatment |
WO2014208525A1 (ja) * | 2013-06-28 | 2014-12-31 | 国立大学法人 佐賀大学 | 貼付型人工皮膚製剤 |
US9517163B2 (en) | 2013-07-03 | 2016-12-13 | 3K Anesthesia Innovations, Llp | Pre-stressed pressure device |
AU2014286868B2 (en) | 2013-07-03 | 2019-12-19 | Klox Technologies Inc. | Biophotonic compositions comprising a chromophore and a gelling agent for treating wounds |
JP6169275B2 (ja) * | 2013-07-18 | 2017-07-26 | ザ ジェネラル ホスピタル コーポレイション | 血管処置システム、血管処置方法及び血管処置キット |
WO2015021434A2 (en) | 2013-08-09 | 2015-02-12 | Cytrellis Biosystems, Inc. | Methods and apparatuses for skin treatment using non-thermal tissue ablation |
AU2014306357A1 (en) * | 2013-08-16 | 2016-02-11 | Bioconix Pty Ltd | A substrate |
JP6815864B2 (ja) | 2013-10-02 | 2021-01-20 | エスアールジーアイ ホールディングス エルエルシーSrgi Holdings Llc | ピクセルアレイ医療デバイス及び方法 |
ES2827049T3 (es) | 2013-10-02 | 2021-05-19 | Srgi Holdings Llc | Dispositivos médicos de conjunto de píxeles |
USD733305S1 (en) | 2013-10-25 | 2015-06-30 | Medtronic Vascular, Inc. | Tissue compression apparatus |
US9955978B2 (en) | 2013-10-25 | 2018-05-01 | Medtronic Vascular, Inc. | Tissue compression device with multi-chamber bladder |
US11229452B2 (en) | 2013-12-06 | 2022-01-25 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
US11937846B2 (en) | 2013-12-06 | 2024-03-26 | Srgi Holdings Llc | Pixel array medical systems, devices and methods |
US20170296214A1 (en) | 2013-12-06 | 2017-10-19 | Edward KNOWLTON | Pixel array medical systems, devices and methods |
US10953143B2 (en) | 2013-12-19 | 2021-03-23 | Cytrellis Biosystems, Inc. | Methods and devices for manipulating subdermal fat |
KR102353789B1 (ko) | 2014-01-05 | 2022-01-19 | 집라인 메디칼, 인크. | 계장된 상처 봉합 기구 |
AR099941A1 (es) | 2014-04-01 | 2016-08-31 | Klox Tech Inc | Composiciones para relleno de tejido y métodos de uso |
US10092297B2 (en) | 2014-04-25 | 2018-10-09 | Medtronic Vascular, Inc. | Tissue compression device with fixation and tension straps |
WO2015164923A1 (en) | 2014-04-29 | 2015-11-05 | Roffe Medical Holdings Pty Ltd | Tissue closing method and apparatus |
CA2951513A1 (en) | 2014-06-09 | 2015-12-17 | Klox Technologies Inc. | Silicone-based biophotonic compositions and uses thereof |
AU2015346141B2 (en) | 2014-11-14 | 2021-07-22 | Cytrellis Biosystems, Inc. | Devices and methods for ablation of the skin |
KR20170095379A (ko) * | 2014-12-18 | 2017-08-22 | 로레알 | 선케어 조성물 및 방법 |
WO2016106185A1 (en) * | 2014-12-22 | 2016-06-30 | The Cleveland Clinic Foundation | Apparatus and method for assisting with wound closure |
JP6805157B2 (ja) | 2015-02-05 | 2020-12-23 | エスアールジーアイ ホールディングス エルエルシーSrgi Holdings Llc | ピクセルアレイ医療システム、デバイスおよび方法 |
TWD179958S (zh) | 2015-04-20 | 2016-12-01 | 思拜德泰克有限公司 | 縫合帶之離型紙 |
WO2016194395A1 (ja) * | 2015-05-29 | 2016-12-08 | 株式会社共和 | 医療用テープ |
JP6034999B1 (ja) * | 2015-05-29 | 2016-11-30 | 株式会社共和 | 医療用テープ |
US11980389B2 (en) | 2015-08-31 | 2024-05-14 | Srgi Holdings Llc | Handed spiral slotted scalpet array |
US11490952B2 (en) | 2015-08-31 | 2022-11-08 | Srgi Holdings, Llc | Pixel array medical devices and methods |
US11759231B2 (en) | 2015-08-31 | 2023-09-19 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
JP6537618B2 (ja) * | 2015-09-11 | 2019-07-03 | フクダ電子株式会社 | センサーシート |
US10945724B2 (en) * | 2015-09-25 | 2021-03-16 | Microkoll, Inc. | Apparatus and methods for adhesion |
US11564706B2 (en) | 2019-10-28 | 2023-01-31 | Srgi Holdings, Llc | Pixel array medical systems, devices and methods |
WO2017147399A1 (en) * | 2016-02-25 | 2017-08-31 | The General Hospital Corporation | Method and apparatus for tightening skin and other tissues |
EP3435890A1 (en) | 2016-03-29 | 2019-02-06 | Cytrellis Biosystems, Inc. | Devices and methods for cosmetic skin resurfacing |
US11135351B2 (en) * | 2016-08-30 | 2021-10-05 | Smith & Nephew Plc | Systems and methods for applying reduced pressure therapy |
EP3515323A4 (en) | 2016-09-21 | 2020-06-10 | Cytrellis Biosystems, Inc. | COSMETIC RESTRUCTURING DEVICES AND METHODS |
EP4252675A3 (en) | 2016-10-21 | 2023-11-15 | Brijjit Medical, Inc. | Force modulating tissue bridges |
WO2018081795A1 (en) | 2016-10-31 | 2018-05-03 | Zipline Medical, Inc. | Systems and methods for monitoring physical therapy of the knee and other joints |
US10617570B2 (en) * | 2016-12-19 | 2020-04-14 | Kevin Gene Abelbeck | Wound closing bandage |
EP3573554B1 (en) * | 2017-01-27 | 2022-08-03 | Apyx Medical Corporation | Apparatus for cold plasma skin resurfacing |
US11998268B2 (en) * | 2017-05-19 | 2024-06-04 | Sciton, Inc. | System and methods for treating skin |
KR101873889B1 (ko) * | 2017-09-08 | 2018-07-04 | 이정윤 | 장력 감쇄식 비후성 반흔 감소필름 |
US10667597B2 (en) * | 2017-10-20 | 2020-06-02 | L'oreal | Anti-aging tapes |
USD876641S1 (en) | 2017-10-20 | 2020-02-25 | Emrge, Llc. | Medical article for treating a wound and/or scar tissue |
US11376149B2 (en) * | 2017-10-23 | 2022-07-05 | Ribcure Co., Ltd. | Patch with expansion support effect |
US20190262184A1 (en) * | 2018-02-26 | 2019-08-29 | Wesley G. Wilson | Therapy Tape |
US20200016007A1 (en) * | 2018-07-10 | 2020-01-16 | BondTrue, LLC | Pressure applying dressing |
GB2574074B (en) | 2018-07-27 | 2020-05-20 | Mclaren Applied Tech Ltd | Time synchronisation |
WO2020166744A1 (ko) * | 2019-02-15 | 2020-08-20 | 주식회사 하이로닉 | 변형 구조 마이크로 니들 및 피부 드레싱용 패드를 이용한 피부 리프팅 방법 |
US11389346B2 (en) * | 2019-08-22 | 2022-07-19 | DePuy Synthes Products, Inc. | Skin compression device and methods of production and use thereof |
US11484345B2 (en) | 2019-10-02 | 2022-11-01 | DePuy Synthes Products, Inc. | Skin morphing and tension distributing system for external fixation and methods of use thereof |
GB2588236B (en) | 2019-10-18 | 2024-03-20 | Mclaren Applied Ltd | Gyroscope bias estimation |
US20220379018A1 (en) | 2019-12-10 | 2022-12-01 | Neodyne Biosciences, Inc. | Tensioned infusion systems with removable hubs |
ES1248484Y (es) * | 2020-05-06 | 2020-09-16 | Servicio Cantabro De Salud | Aposito para terapias de presion negativa |
US20210361005A1 (en) * | 2020-05-20 | 2021-11-25 | Curian Health Llc | Face mask |
US11272884B2 (en) * | 2020-06-04 | 2022-03-15 | Medtronic Minimed, Inc. | Liner for adhesive skin patch |
KR102247709B1 (ko) * | 2020-08-06 | 2021-05-07 | 이민우 | 주사액 주사장치 |
US11806050B2 (en) | 2020-09-21 | 2023-11-07 | DePuy Synthes Products, Inc. | Tension isolating adjustable adapter for external fixation and methods of production and use thereof |
EP4272520A1 (en) | 2020-12-31 | 2023-11-08 | Sofwave Medical Ltd. | Cooling of ultrasound energizers mounted on printed circuit boards |
USD980434S1 (en) | 2021-01-14 | 2023-03-07 | Emrge, Llc | Medical article for treating a wound and/or scar tissue |
CN117337143A (zh) * | 2021-03-16 | 2024-01-02 | 维纳斯概念公司 | 用于处理皮肤的方法和装置 |
CN113180918A (zh) * | 2021-04-15 | 2021-07-30 | 周天珍 | 一种新生儿脐带保护带 |
JP2024517188A (ja) * | 2021-05-07 | 2024-04-19 | デボル,インコーポレイテッド | 組織欠損閉鎖のための方法及びデバイス |
CN113209001B (zh) * | 2021-05-17 | 2024-04-16 | 哈尔滨医科大学 | 祛疤微针贴 |
AU2022393285A1 (en) * | 2021-11-22 | 2024-07-04 | Sofwave Medical Ltd. | Vector tightening |
JP7198384B1 (ja) * | 2022-06-28 | 2022-12-28 | 有限会社ちょうりゅう | 医療テープの製造方法 |
Family Cites Families (205)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US363538A (en) | 1887-05-24 | Suegical | ||
US114750A (en) | 1871-05-16 | Improvement in sticking or adhesive plasters | ||
US633050A (en) * | 1899-04-21 | 1899-09-12 | Marie Louise Spenard | Garment-stretcher. |
US1074413A (en) | 1913-03-06 | 1913-09-30 | Harry C De Baun | Suture appliance. |
US1774489A (en) | 1927-12-20 | 1930-08-26 | Sarason David | Strip of sticking plaster |
US1969188A (en) | 1932-10-21 | 1934-08-07 | George W Spicer | Means for drawing and holding wounds |
US2018517A (en) | 1933-04-01 | 1935-10-22 | Fetter Edward | Elastic adhesive bandage |
US2303131A (en) | 1941-04-25 | 1942-11-24 | Eva M Morgan | Suturable surgical adhesive material and method of using same |
US2371978A (en) | 1941-12-13 | 1945-03-20 | Roy G Perham | Clamp for retaining the edges of a wound in apposition |
US2421193A (en) | 1943-08-02 | 1947-05-27 | Cleveland Clinic Foundation | Surgical dressing |
US2472009A (en) | 1945-08-01 | 1949-05-31 | Cleveland Clinic Foundation | Surgical dressing |
US2714382A (en) | 1952-07-21 | 1955-08-02 | Alcala Maximino Solis | Emergency bandages |
US2722220A (en) | 1953-06-17 | 1955-11-01 | Maxime A Mestrand | Suture bandage |
US2762371A (en) | 1955-01-31 | 1956-09-11 | Truby B Guio | Draw-type twin bandage |
US3103218A (en) | 1962-07-11 | 1963-09-10 | Edward P Ajemian | Dressing retainer or strap |
US3402716A (en) | 1964-01-30 | 1968-09-24 | Surgical Devices | Adhesive strip suture |
AT295031B (de) | 1967-01-10 | 1971-12-27 | Radivoje Dr Vukojevic | Klebeband als Ersatz für eine Hautnaht |
US3575782A (en) | 1967-05-19 | 1971-04-20 | Minnesota Mining & Mfg | Elastic shirred web product |
NO134790C (no) | 1968-07-09 | 1984-03-22 | Smith & Nephew | Klebende,; trykkfoelsomt, vanndamp-permeabelt produkt for bruk paa hud hos mennesker. |
US3487836A (en) | 1968-07-16 | 1970-01-06 | Benjamin W Niebel | Surgical strip stitch |
US3613679A (en) * | 1969-10-01 | 1971-10-19 | Patricia W Bijou | Elastic bandage with tension indicator |
US3698395A (en) | 1971-03-12 | 1972-10-17 | Harrith M Hasson | Surgical closure |
US3926193A (en) | 1971-12-17 | 1975-12-16 | Harrith M Hasson | Surgical closure having ease of assembly |
US3863640A (en) | 1973-04-27 | 1975-02-04 | Charles B Haverstock | Bandage construction |
US3983878A (en) | 1973-12-10 | 1976-10-05 | Claude Edward Kawchitch | Surgical appliance |
US3933158A (en) | 1974-02-15 | 1976-01-20 | Haverstock Charles B | Skin closure means |
CA1044980A (en) * | 1975-07-04 | 1978-12-26 | Canadian Patents And Development Limited | Therapeutic device for skin lesions |
US4141363A (en) | 1975-11-20 | 1979-02-27 | James Jesse L | Interlocking suture |
US4073298A (en) | 1976-08-03 | 1978-02-14 | New Research & Development Lab., Inc. | Wound clip |
US4173131A (en) | 1977-08-30 | 1979-11-06 | The Kendall Co. | Porous elastic bandage |
DE2912129C2 (de) | 1979-03-28 | 1986-06-12 | Karl Otto Braun Kg, 6759 Wolfstein | Verfahren zur Herstellung einer kohäsiven, starren oder elastischen Binde für Fixierverbände, Kompressions- und Stützverbände und dauerelastische Kompressions- und Stützverbände für medizinische Zwecke |
US4222383A (en) | 1978-08-07 | 1980-09-16 | Schossow George W | Surgical drape and suture |
GB2039785B (en) | 1978-11-09 | 1983-04-13 | Sanyo Kokusaku Pulp Co | Pressure sensitive adhesive products and the method for preparation of the same |
JPS55126817U (ja) | 1979-03-05 | 1980-09-08 | ||
EP0028452A1 (en) | 1979-09-27 | 1981-05-13 | Smith and Nephew Associated Companies p.l.c. | Adhesive skin closure |
US4346700A (en) | 1979-11-16 | 1982-08-31 | Minnesota Mining & Manufacturing Company | Pressure-sensitive adhesive sheet material |
US4423731A (en) | 1980-09-09 | 1984-01-03 | Roomi Reyadh K | Surgical dressings |
US4496535A (en) | 1980-11-12 | 1985-01-29 | Tyndale Plains-Hunter, Ltd. | Polyurethane polyene compositions |
US4413621A (en) | 1981-12-11 | 1983-11-08 | Johnson & Johnson Products, Inc. | Film dressing |
US4447482A (en) | 1982-01-21 | 1984-05-08 | Shur Medical Corporation | Wound closure tape and applicator therefor |
US4605005A (en) | 1982-04-12 | 1986-08-12 | Kells Medical, Inc. | Wound closure device and method for using same |
US4702251A (en) | 1982-04-12 | 1987-10-27 | Kells Medical, Incorporated | Wound closure device |
US4531521A (en) | 1983-03-03 | 1985-07-30 | Haverstock Charles B | Skin closure means |
US4535772A (en) | 1983-03-10 | 1985-08-20 | Kells Medical, Incorporated | Skin closure device |
US4549653A (en) | 1983-09-06 | 1985-10-29 | Johnson & Johnson Products, Inc. | Adhesive bandage and package |
US4539990A (en) | 1983-09-16 | 1985-09-10 | Stivala Oscar G | Sutureless closure system |
GB2157958A (en) * | 1984-05-03 | 1985-11-06 | Ernest Edward Austen Bedding | Ball game net support |
FR2566266B1 (fr) | 1984-06-25 | 1986-09-19 | Beghin Say Sa | Pansement adhesif permettant une application aisee sur la peau |
US4950282A (en) | 1984-10-22 | 1990-08-21 | Genetic Laboratories, Inc. | Wound closure strips |
US4780168A (en) | 1984-10-22 | 1988-10-25 | Genetic Laboratories, Inc. | Wound closure strips |
USRE33353E (en) | 1985-01-24 | 1990-09-25 | Minnesota Mining And Manufacturing Company | Thin film surgical dressing with delivery system |
US4598004A (en) | 1985-01-24 | 1986-07-01 | Minnesota Mining And Manufacturing Company | Thin film surgical dressing with delivery system |
US4653492A (en) * | 1985-02-13 | 1987-03-31 | Dorothy Parsons | Elastic bandage |
US4646731A (en) | 1985-05-20 | 1987-03-03 | Brower Arthur B | Self adhesive suture and bandage |
US4787381A (en) | 1986-01-21 | 1988-11-29 | Tecnol, Inc. | Abdominal binder |
US4742826A (en) | 1986-04-07 | 1988-05-10 | Mclorg Anthony B | Cicatrisive strip with bias |
US4696301A (en) | 1986-07-16 | 1987-09-29 | Barabe David J | Wound closing method |
US4706661A (en) | 1986-10-31 | 1987-11-17 | Barrett David M | Wound closure and observation device having a no-contact protective covering |
DE3706599A1 (de) | 1986-12-16 | 1988-07-07 | Kaessmann Hans Juergen Prof Dr | Vorrichtung zum verschliessen einer wunde und verfahren zur applikation dieser vorrichtung |
US4807613A (en) | 1986-12-22 | 1989-02-28 | Koehnke Raechelle K | Bandage and shield |
US4815468A (en) | 1987-01-09 | 1989-03-28 | Annand David S | Sutureless closure |
US4984584A (en) | 1987-01-16 | 1991-01-15 | Riker Laboratories, Inc. | High elastic modulus bandage |
US4732146A (en) | 1987-08-14 | 1988-03-22 | Fasline Ronald J | Wound dressing retention apparatus |
US4825866A (en) | 1987-08-27 | 1989-05-02 | Robert Pierce | Wound closure device |
DE3809348A1 (de) | 1987-10-23 | 1989-05-03 | Beiersdorf Ag | Selbstklebendes wundnahtpflaster |
US5026389A (en) | 1988-07-28 | 1991-06-25 | Thieler William R | Method and apparatus for opening and closing surgical wounds |
US4915102A (en) | 1988-09-01 | 1990-04-10 | Bertek, Inc. | Hinged dermal applicator |
US5047047A (en) | 1988-10-26 | 1991-09-10 | Inbae Yoon | Wound closing device |
US4924866A (en) | 1988-10-26 | 1990-05-15 | Inbae Yoon | Wound-closing device |
US4917929A (en) | 1989-01-18 | 1990-04-17 | Minnesota Mining And Manufacturing Company | One piece adhesive bandage and package unit |
US5106629A (en) | 1989-10-20 | 1992-04-21 | Ndm Acquisition Corp. | Transparent hydrogel wound dressing |
US5127412A (en) | 1990-03-14 | 1992-07-07 | Cosmetto Aristodeme J | Skin tensioning |
US5066299A (en) | 1990-06-29 | 1991-11-19 | Bellingham Medical, Inc. | Quick use suture package |
US5058579A (en) | 1990-08-09 | 1991-10-22 | Terry Deborah A | Tracheostomy dressing |
US5263970A (en) | 1990-08-10 | 1993-11-23 | Preller Siegfried F | Surgical dressing for closing a wound |
RU2019138C1 (ru) | 1991-07-15 | 1994-09-15 | Научно-производственное объединение "Мединструмент" | Инструмент для сведения и разведения краев раны |
US5259835A (en) | 1991-08-29 | 1993-11-09 | Tri-Point Medical L.P. | Wound closure means and method using flowable adhesive |
US5234462A (en) | 1991-08-29 | 1993-08-10 | Tufts University | Method and kit for accelerating the closing of open skin wounds |
WO1993007841A1 (en) | 1991-10-23 | 1993-04-29 | Gary Wayne Cummings | Wound dressing system |
US5176703A (en) | 1991-10-30 | 1993-01-05 | Peterson Meldon L | Sutureless closure for a skin wound or incision |
WO1993008777A1 (en) | 1991-11-06 | 1993-05-13 | Bioderm, Inc. | Occlusive wound dressing and applicator |
US5522879A (en) | 1991-11-12 | 1996-06-04 | Ethicon, Inc. | Piezoelectric biomedical device |
DK168420B1 (da) | 1992-03-27 | 1994-03-28 | Coloplast As | Varmebandage |
FR2690840B1 (fr) | 1992-05-07 | 1994-08-19 | Patrick Frechet | Dispositif d'extension de tissu vivant. |
CA2094230A1 (en) | 1992-05-15 | 1993-11-16 | James J. Krejci | Primer coating, polyester film having a primer coating, and a process for coating film |
US5779659A (en) | 1992-12-01 | 1998-07-14 | Convatec Limited | Elastic bandage with tension indicator |
US5552162A (en) | 1993-02-09 | 1996-09-03 | Arch Development Corporation | Method for improvement of scar size and appearance |
GB9310185D0 (en) | 1993-05-18 | 1993-06-30 | Giltech Ltd | Wound dressing |
US5441540A (en) | 1993-09-20 | 1995-08-15 | Kim; Paul S. | Method and apparatus for skin tissue expansion |
US5333753A (en) | 1993-12-06 | 1994-08-02 | The Kendall Company | Finger bandage package and dispenser |
US5520762A (en) | 1993-12-23 | 1996-05-28 | Wilshire Technologies, Inc. (Wilshire Medical Products Division) | Method of manufucturing a wound dressing delivery system |
US5507775A (en) | 1994-01-21 | 1996-04-16 | Progressive Surgical Products Inc. | Tissue expansion and approximation device |
US5662714A (en) * | 1994-01-21 | 1997-09-02 | M.X.M. | Device for extending living tissues |
US5998694A (en) | 1994-03-02 | 1999-12-07 | Jensen; Ole R. | Occlusive dressing with release sheet having extended tabs |
US5383900A (en) | 1994-06-01 | 1995-01-24 | Medi-Flex Hospital Products | Tape applicator |
SE503384C2 (sv) | 1994-09-20 | 1996-06-03 | Moelnlycke Ab | Förband innefattande en silikongel i vilken ett bärarmaterial är inneslutet |
US5628724A (en) | 1994-12-29 | 1997-05-13 | Deroyal Industries, Inc. | Wound dressing and delivery system therefor |
US5885254A (en) | 1995-01-03 | 1999-03-23 | Matyas; Melanie E. | Replaceable flexible protective cover for an infusion device |
US5649960A (en) | 1995-02-03 | 1997-07-22 | Pavletic; Michael M. | Apparatus and method for accelerating the stretching of skin |
US5658356A (en) | 1995-05-05 | 1997-08-19 | Rayovac Corporation | Metal-air cathode can having reduced corner radius and electrochemical cells made therewith |
US5562705A (en) | 1995-05-23 | 1996-10-08 | Whiteford; Carlton L. | Sutureless wound closure device |
US5759560A (en) | 1995-07-27 | 1998-06-02 | Bio Med Sciences, Inc. | Silicone thermoplastic sheeting for scar treatment and useful article thereof; process of manufacture and use |
US8084051B1 (en) | 1995-11-13 | 2011-12-27 | Bio Med Sciences, Inc. | Therapeutic medical garments with silicone sheeting component for scar treatment, process of manufacture and use |
BE1009950A6 (nl) | 1996-02-21 | 1997-11-04 | Den Heede Marie Therese Van | Composietmateriaal voor medische, cosmetische en sport doeleinden en werkwijzen ter vervaardiging hiervan. |
NZ332574A (en) | 1996-05-10 | 2002-06-28 | Wallace J Beaudry | Nasal epidermal lifting mechanism with elastic or resilient portion over pad |
US7022891B2 (en) | 1996-05-10 | 2006-04-04 | Wallace J Beaudry | Dressing and an epidermal positioning mechanism and method for using same |
AU715042B2 (en) | 1996-05-24 | 2000-01-13 | Coloplast A/S | A permanently deformable dressing |
US5758662A (en) | 1996-08-02 | 1998-06-02 | Hall; J. Rodney | Device for shielding an incision |
US5919476A (en) | 1997-09-29 | 1999-07-06 | Pmt Corporation | Reinforced gel sheeting for scar treatment |
US5947998A (en) | 1997-09-30 | 1999-09-07 | Technical Alternatives, Ltd. | Wound closure strips and packages thereof |
US20050245966A1 (en) | 1997-12-17 | 2005-11-03 | Hammerslag Julius G | Controlled viscosity tissue adhesive |
US6043406A (en) | 1998-02-27 | 2000-03-28 | Ferris Mfg, Corp. | Thin film wound dressing and method for making same |
US6007564A (en) | 1998-03-05 | 1999-12-28 | Haverstock; Charles B. | Skin closure device for surgical procedures |
JPH11319065A (ja) | 1998-05-18 | 1999-11-24 | Fuji Yakuhin:Kk | シリコーンシート及びこれを用いた外科用包帯 |
DE19841550A1 (de) | 1998-09-11 | 2000-03-23 | Beiersdorf Ag | Verbandmaterial auf Folienbasis |
US6343224B1 (en) | 1998-10-15 | 2002-01-29 | Sensidyne, Inc. | Reusable pulse oximeter probe and disposable bandage apparatus |
WO2002080797A1 (en) | 1998-10-23 | 2002-10-17 | Sherwood Services Ag | Vessel sealing instrument |
US6469066B1 (en) | 1998-12-18 | 2002-10-22 | Palladin Healthcare International, Ltd. | Composition for pain mediation and apparatus and method of use thereof |
US6284941B1 (en) | 1999-03-09 | 2001-09-04 | Craig M. Cox | Bandage having a scar treatment pad for scar management and scar repair |
US6261976B1 (en) * | 1999-03-18 | 2001-07-17 | Chartered Semiconductor Manufacturing Ltd. | Method of forming low pressure silicon oxynitride dielectrics having high reliability |
SK19412001A3 (sk) | 1999-07-02 | 2002-08-06 | The Procter & Gamble Company | Dávkovací systém na dodávanie látky ústnej hygieny do dutiny ústnej a spôsob dávkovania |
US6120525A (en) | 1999-07-14 | 2000-09-19 | Westcott; Mitchell S. | Skin tensioning device |
US6297420B1 (en) | 1999-10-29 | 2001-10-02 | Arno J. Heincke | Method of selecting an item to match a person's skin tone |
US6329564B1 (en) | 1999-11-29 | 2001-12-11 | Michael Lebner | Bandage for wound or incision closure |
US6264976B1 (en) * | 1999-11-29 | 2001-07-24 | 3M Innovative Properties Company | Absorbent pad dressing frame delivery system |
US6831205B2 (en) | 1999-11-29 | 2004-12-14 | Clozex Medical, Llc | Bandage for wound or incision closure |
ES2290120T3 (es) | 2000-03-17 | 2008-02-16 | Avocet Polymer Technologies, Inc. | Procedimientos para mejorar la dimension y el aspecto de una herida. |
US7361185B2 (en) * | 2001-05-09 | 2008-04-22 | Canica Design, Inc. | Clinical and surgical system and method for moving and stretching plastic tissue |
US6485503B2 (en) | 2000-05-19 | 2002-11-26 | Coapt Systems, Inc. | Multi-point tissue tension distribution device, a brow and face lift variation, and a method of tissue approximation using the device |
IL138099A0 (en) | 2000-08-25 | 2001-10-31 | Naimer Richard | Bandage |
US6572878B1 (en) | 2000-09-07 | 2003-06-03 | Robert Blaine | Method and device for treating scars |
US7066182B1 (en) * | 2000-09-27 | 2006-06-27 | 3M Innovative Properties Company | Conformable adhesive wound closures |
AU2002215714A1 (en) | 2000-12-04 | 2002-06-18 | Bernard Hoste | Silicone gel sheet for treatment of scar tissue |
US6410818B1 (en) | 2000-12-12 | 2002-06-25 | Michael F. Oyaski | Device and method for promoting healing of topical stress cracks |
US20080214988A1 (en) | 2000-12-28 | 2008-09-04 | Palomar Medical Technologies, Inc. | Methods And Devices For Fractional Ablation Of Tissue |
BR0206691B1 (pt) | 2001-01-24 | 2011-06-28 | molde oftálmico compreendendo polìmero de memória de forma. | |
US6986855B1 (en) | 2001-01-24 | 2006-01-17 | Cornerstone Research Group | Structural and optical applications for shape memory polymers (SMP) |
US6726696B1 (en) | 2001-04-24 | 2004-04-27 | Advanced Catheter Engineering, Inc. | Patches and collars for medical applications and methods of use |
ATE438418T1 (de) | 2001-05-01 | 2009-08-15 | Av Topchiev Inst Petrochemical | Hydrogel-zusammensetzungen |
AU2002315027A1 (en) | 2001-05-15 | 2002-11-25 | Children's Medical Center Corporation | Methods and apparatus for application of micro-mechanical forces to tissues |
US20020193723A1 (en) | 2001-06-13 | 2002-12-19 | Batdorf David B. | Compressible foam wound dressing |
US6634653B2 (en) | 2001-07-17 | 2003-10-21 | Probir Chatterjea & Associates, Inc. | Ride control system for construction equipment |
US7066934B2 (en) | 2001-07-19 | 2006-06-27 | Loma Linda University | Adhesive including medicament and device and method for applying same |
US7004915B2 (en) | 2001-08-24 | 2006-02-28 | Kci Licensing, Inc. | Negative pressure assisted tissue treatment system |
DE10212866A1 (de) | 2002-03-22 | 2003-10-09 | Beiersdorf Ag | Narbenreduktionspflaster |
US8187326B2 (en) | 2002-05-22 | 2012-05-29 | Advanced Technologies And Regenerative Medicine, Llc. | Attachment of absorbable tissue scaffolds to fixation devices |
US6870074B2 (en) | 2002-05-23 | 2005-03-22 | Hollister Incorporated | Thin film scar dressing and use thereof |
US7100615B1 (en) * | 2002-11-25 | 2006-09-05 | Cms-Dental Aps | Low level laser therapy system |
US7122712B2 (en) | 2002-12-02 | 2006-10-17 | Lutri Thomas P | Surgical bandage and methods for treating open wounds |
US7612248B2 (en) | 2002-12-19 | 2009-11-03 | 3M Innovative Properties Company | Absorbent medical articles |
US7230154B2 (en) * | 2002-12-31 | 2007-06-12 | Ossur Hf | Wound dressing |
JP4413500B2 (ja) | 2003-01-24 | 2010-02-10 | 株式会社ドクターモア | 傷痕修復用シート |
US6838589B2 (en) * | 2003-02-19 | 2005-01-04 | 3M Innovative Properties Company | Conformable wound dressing |
US20040204740A1 (en) | 2003-04-14 | 2004-10-14 | Weiser Leslie Philipp | Method and apparatus for closing wounds without sutures |
EP1635858A4 (en) | 2003-05-29 | 2009-08-26 | Scripps Research Inst | TARGETED RELEASE ON CELLS EXPRESSING LEGUMINUM |
US7414168B2 (en) | 2003-07-24 | 2008-08-19 | Clozex Medical Llc | Device for laceration or incision closure |
US7354446B2 (en) | 2003-07-24 | 2008-04-08 | Clozex Medical, Llc | Device for laceration or incision closure |
US20050034731A1 (en) * | 2003-08-13 | 2005-02-17 | Rousseau Robert A. | Surgical wound closure device |
US8187627B2 (en) | 2003-09-05 | 2012-05-29 | Loma Linda University Medical Center | Dressing delivery system for internal wounds |
US7232454B2 (en) | 2003-09-29 | 2007-06-19 | Ethicon, Inc. | Surgical wound closure/transfer marking device |
US7332641B2 (en) | 2003-10-10 | 2008-02-19 | Clozex Medical Llc | Interlaced compositions and methods of production |
CN1608604A (zh) | 2003-10-23 | 2005-04-27 | 强生消费者公司 | 具有改进背衬材料的胶粘绷带 |
NL1024793C1 (nl) | 2003-11-17 | 2005-05-18 | Therese Van Den Eede | Silicone producten en werkwijze voor het maken van silicone producten. |
US8157855B2 (en) | 2003-12-05 | 2012-04-17 | Boston Scientific Scimed, Inc. | Detachable segment stent |
US8535299B2 (en) | 2004-01-23 | 2013-09-17 | Joseph Giovannoli | Method and apparatus for skin reduction |
US20050182443A1 (en) | 2004-02-18 | 2005-08-18 | Closure Medical Corporation | Adhesive-containing wound closure device and method |
JP4971133B2 (ja) * | 2004-04-01 | 2012-07-11 | ザ ジェネラル ホスピタル コーポレイション | 皮膚科治療のための装置 |
AU2005231443B2 (en) | 2004-04-01 | 2012-02-23 | The General Hospital Corporation | Method and apparatus for dermatological treatment and tissue reshaping |
GB0407502D0 (en) * | 2004-04-02 | 2004-05-05 | Inotec Amd Ltd | Hyperbaric dressing |
US20060037091A1 (en) | 2004-05-24 | 2006-02-16 | Gurtner Geoffrey C | Method for producing hypertrophic scarring animal model for identification of agents for prevention and treatment of human hypertrophic scarring |
US20050274453A1 (en) | 2004-06-10 | 2005-12-15 | Anvar Bardia A | Adhesive strip applicator |
US20060009099A1 (en) | 2004-07-12 | 2006-01-12 | Closure Medical Corporation | Adhesive-containing wound closure device and method |
US20060282135A1 (en) * | 2004-07-12 | 2006-12-14 | Stcmedica Cell Technologies, Inc. | Radiation separating shield for skin treatment |
US7135606B1 (en) | 2004-07-15 | 2006-11-14 | Terrance Dozier | Wound dressing |
EP1778142A4 (en) | 2004-07-16 | 2011-02-02 | Polyremedy Inc | DRESSING AND APPARATUS FOR MANUFACTURING THE SAME |
US8157839B2 (en) | 2004-08-31 | 2012-04-17 | Wadsworth Medical Technologies, Inc. | Systems and methods for closing a tissue opening |
US7563941B2 (en) | 2004-09-10 | 2009-07-21 | Clozex Medical, Llc | Modular wound dressing system |
GB2424584A (en) * | 2005-03-30 | 2006-10-04 | Deborah Calvert | Stoma device for maintaining a gastrostomy and/or urostomy stoma |
US20060246802A1 (en) | 2005-04-29 | 2006-11-02 | Hughes Janis W | Color change laminate material |
AU2006247595B2 (en) | 2005-05-12 | 2012-02-09 | Canica Design Inc. | Dynamic tensioning system and method |
US7976571B2 (en) * | 2005-08-02 | 2011-07-12 | Wolfgang Neuberger | Photodynamic therapy irradiation system for the treatment of superficial hyperproliferative tissue growth |
ES2442854T3 (es) | 2005-09-06 | 2014-02-13 | Sigvaris Management Ag | Venda tricotada |
US20070129776A1 (en) * | 2005-10-20 | 2007-06-07 | Light Sciences Llc | External wearable light therapy treatment systems |
US8586818B2 (en) | 2005-12-15 | 2013-11-19 | Aalnex, Inc. | Wound shield |
US20070239232A1 (en) * | 2006-03-28 | 2007-10-11 | Eastman Kodak Company | Light guide based light therapy device |
EP2010087B1 (en) * | 2006-04-07 | 2014-11-05 | The General Hospital Corporation | Apparatus for producing thermal damage within the skin |
US7837706B2 (en) | 2006-05-31 | 2010-11-23 | Boston Scientific Scimed, Inc. | Tissue attachment device, system, and method |
KR100886633B1 (ko) * | 2006-07-14 | 2009-03-04 | 호남석유화학 주식회사 | 전면부에 피부를 통해 체내로 전달하고자 하는 물질의 수용공간을 갖는 피부 침투용 미세 돌기 장치 |
BRPI0715075B1 (pt) | 2006-08-03 | 2021-11-30 | The Board Of Trustees Of The Leland Stanford Junior University | Bandagem para melhorar a formação de uma cicatriz ou queloide em um local de ferimento |
US7696399B2 (en) | 2006-08-23 | 2010-04-13 | Rogers Gary S | Sutureless wound closure and method of application |
US7834232B2 (en) | 2006-12-02 | 2010-11-16 | Omnitek Partners Llc | Shape and pressure adjustable dressing |
US20080208098A1 (en) * | 2007-02-28 | 2008-08-28 | Lynda Rennix | Methods, apparatus, and products for wound care |
US8592640B2 (en) | 2009-08-11 | 2013-11-26 | Neodyne Biosciences, Inc. | Devices and methods for dressing applicators |
US9358009B2 (en) | 2007-08-03 | 2016-06-07 | Neodyne Biosciences, Inc. | Skin straining devices and methods |
EP2161011B2 (de) * | 2008-09-03 | 2015-05-20 | Gert Pistor | Wundschutz |
US8388631B2 (en) | 2009-01-23 | 2013-03-05 | Restoration Robotics, Inc. | Skin tensioner for hair transplantation |
KR20100094700A (ko) * | 2009-02-19 | 2010-08-27 | 전민용 | 마이크로니들 스탬프와 연동된 치료 및 스킨케어 시스템 |
US20100280428A1 (en) * | 2009-04-25 | 2010-11-04 | Widgerow Alan D | Medical device for shrinking open wounds |
KR101033514B1 (ko) * | 2009-06-02 | 2011-05-09 | (주)마이티시스템 | 유연한 미세바늘 패치 시스템 및 그 제작방법 |
CN201481501U (zh) * | 2009-08-05 | 2010-05-26 | 北华大学 | 微创面部皮肤-筋膜提紧导引器 |
US9358099B2 (en) | 2009-11-30 | 2016-06-07 | Biflow Medical Ltd. | Method of implanting a stent graft and creating a fenestration therein |
US8591447B2 (en) | 2010-06-29 | 2013-11-26 | Jennifer DiGrazia | Wound and bandage protection system and method |
KR101944844B1 (ko) | 2011-01-07 | 2019-02-01 | 네오다인 바이오사이언시스, 인코포레이티드 | 상처 또는 피부 치료 장치 및 방법 |
KR102185635B1 (ko) | 2011-03-03 | 2020-12-03 | 네오다인 바이오사이언시스, 인코포레이티드 | 피부 타이트닝을 위한 장치 및 방법 |
KR102046977B1 (ko) * | 2011-03-31 | 2019-11-20 | 이엠알지이, 엘엘씨. | 힘 조정형 조직 브릿지 |
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CN103501739A (zh) | 2014-01-08 |
KR20140010430A (ko) | 2014-01-24 |
JP2014514007A (ja) | 2014-06-19 |
US20170112673A1 (en) | 2017-04-27 |
CN108720995A (zh) | 2018-11-02 |
JP2018029985A (ja) | 2018-03-01 |
EP2680800B1 (en) | 2016-04-27 |
US10857037B2 (en) | 2020-12-08 |
US20190015255A1 (en) | 2019-01-17 |
BR112013022525B1 (pt) | 2020-09-24 |
JP2019213996A (ja) | 2019-12-19 |
EP2680800A1 (en) | 2014-01-08 |
JP6272625B2 (ja) | 2018-01-31 |
US20140088481A1 (en) | 2014-03-27 |
KR102068212B1 (ko) | 2020-01-20 |
US20120226214A1 (en) | 2012-09-06 |
WO2012119131A1 (en) | 2012-09-07 |
CN103501739B (zh) | 2018-06-19 |
US11701262B2 (en) | 2023-07-18 |
BR112013022525A2 (pt) | 2016-11-29 |
EP2680800A4 (en) | 2014-10-29 |
US20120226306A1 (en) | 2012-09-06 |
US20130190673A1 (en) | 2013-07-25 |
CN108720995B (zh) | 2021-12-03 |
KR102185635B1 (ko) | 2020-12-03 |
KR20200010572A (ko) | 2020-01-30 |
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