JP6615758B2 - 水可溶性フィルム中の酵素粒子の使用 - Google Patents
水可溶性フィルム中の酵素粒子の使用 Download PDFInfo
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- JP6615758B2 JP6615758B2 JP2016539033A JP2016539033A JP6615758B2 JP 6615758 B2 JP6615758 B2 JP 6615758B2 JP 2016539033 A JP2016539033 A JP 2016539033A JP 2016539033 A JP2016539033 A JP 2016539033A JP 6615758 B2 JP6615758 B2 JP 6615758B2
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- DGSDBJMBHCQYGN-UHFFFAOYSA-M sodium;2-ethylhexyl sulfate Chemical compound [Na+].CCCCC(CC)COS([O-])(=O)=O DGSDBJMBHCQYGN-UHFFFAOYSA-M 0.000 description 1
- OMSMEHWLFJLBSH-UHFFFAOYSA-M sodium;2-hydroxynaphthalene-1-carboxylate Chemical compound [Na+].C1=CC=CC2=C(C([O-])=O)C(O)=CC=C21 OMSMEHWLFJLBSH-UHFFFAOYSA-M 0.000 description 1
- LIAJJWHZAFEJEZ-UHFFFAOYSA-M sodium;2-hydroxynaphthalene-1-sulfonate Chemical compound [Na+].C1=CC=CC2=C(S([O-])(=O)=O)C(O)=CC=C21 LIAJJWHZAFEJEZ-UHFFFAOYSA-M 0.000 description 1
- AZGINNVTHJQMPB-UHFFFAOYSA-M sodium;2-methylpropane-1-sulfonate;prop-2-enamide Chemical compound [Na+].NC(=O)C=C.CC(C)CS([O-])(=O)=O AZGINNVTHJQMPB-UHFFFAOYSA-M 0.000 description 1
- AXMCIYLNKNGNOT-UHFFFAOYSA-N sodium;3-[[4-[(4-dimethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)-[4-[ethyl-[(3-sulfophenyl)methyl]amino]phenyl]methyl]-n-ethylanilino]methyl]benzenesulfonate Chemical compound [Na+].C=1C=C(C(=C2C=CC(C=C2)=[N+](C)C)C=2C=CC(=CC=2)N(CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C=CC=1N(CC)CC1=CC=CC(S(O)(=O)=O)=C1 AXMCIYLNKNGNOT-UHFFFAOYSA-N 0.000 description 1
- MZSDGDXXBZSFTG-UHFFFAOYSA-M sodium;benzenesulfonate Chemical compound [Na+].[O-]S(=O)(=O)C1=CC=CC=C1 MZSDGDXXBZSFTG-UHFFFAOYSA-M 0.000 description 1
- MWNQXXOSWHCCOZ-UHFFFAOYSA-L sodium;oxido carbonate Chemical compound [Na+].[O-]OC([O-])=O MWNQXXOSWHCCOZ-UHFFFAOYSA-L 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000011044 succinic acid Nutrition 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical compound [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 1
- 229940117986 sulfobetaine Drugs 0.000 description 1
- 150000003457 sulfones Chemical class 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 239000007885 tablet disintegrant Substances 0.000 description 1
- 108010075550 termamyl Proteins 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 150000004685 tetrahydrates Chemical class 0.000 description 1
- 108010031354 thermitase Proteins 0.000 description 1
- 238000003856 thermoforming Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 239000001069 triethyl citrate Substances 0.000 description 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 1
- 235000013769 triethyl citrate Nutrition 0.000 description 1
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
- 235000011178 triphosphate Nutrition 0.000 description 1
- 239000001226 triphosphate Substances 0.000 description 1
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 description 1
- VRVDFJOCCWSFLI-UHFFFAOYSA-K trisodium 3-[[4-[(6-anilino-1-hydroxy-3-sulfonatonaphthalen-2-yl)diazenyl]-5-methoxy-2-methylphenyl]diazenyl]naphthalene-1,5-disulfonate Chemical compound [Na+].[Na+].[Na+].COc1cc(N=Nc2cc(c3cccc(c3c2)S([O-])(=O)=O)S([O-])(=O)=O)c(C)cc1N=Nc1c(O)c2ccc(Nc3ccccc3)cc2cc1S([O-])(=O)=O VRVDFJOCCWSFLI-UHFFFAOYSA-K 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- LSGOVYNHVSXFFJ-UHFFFAOYSA-N vanadate(3-) Chemical compound [O-][V]([O-])([O-])=O LSGOVYNHVSXFFJ-UHFFFAOYSA-N 0.000 description 1
- WQEVDHBJGNOKKO-UHFFFAOYSA-K vanadic acid Chemical compound O[V](O)(O)=O WQEVDHBJGNOKKO-UHFFFAOYSA-K 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 229940030186 xpect Drugs 0.000 description 1
- 238000004383 yellowing Methods 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
- 239000004711 α-olefin Substances 0.000 description 1
Classifications
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
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- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38681—Chemically modified or immobilised enzymes
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- C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
- C08L29/02—Homopolymers or copolymers of unsaturated alcohols
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
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- C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
- C11D17/04—Detergent materials or soaps characterised by their shape or physical properties combined with or containing other objects
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- C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
- C11D17/04—Detergent materials or soaps characterised by their shape or physical properties combined with or containing other objects
- C11D17/041—Compositions releasably affixed on a substrate or incorporated into a dispensing means
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
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- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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Description
本出願は、参照により本明細書に援用される、コンピュータ可読形式の配列表を含有する。
本発明で使用される酵素粒子は、プロテアーゼ、リパーゼ、クチナーゼ、アミラーゼ、カルボヒドラーゼ、セルラーゼ、ペクチナーゼ、マンナナーゼ、アラビナーゼ、ガラクタナーゼ、キシラナーゼ、キサンタナーゼ、DNAse、ペルヒドロラーゼ、そして例えば、オキシダーゼ、ラッカーゼ、ペルオキシダーゼ、ペルオキシゲナーゼおよび/またはハロペルオキシダーゼなどの酸化還元酵素;またはそれらの組み合わせなどの酵素を含有する。
N128C+K178L+T182G+Y305R+G475K;
N128C+K178L+T182G+F202Y+Y305R+D319T+G475K;
S125A+N128C+K178L+T182G+Y305R+G475K;または
S125A+N128C+T131I+T165I+K178L+T182G+Y305R+G475K
の置換を有するものであり、変種は、C末端トランケート型であり、任意選択的に、243位の置換、および/または180位および/または181位の欠失をさらに含んでなる。
(同一残基×100)/(アラインメント長さ−アラインメント中のギャップ総数)。
酵素粒子は、洗剤パウチの区画を形成するために使用される水溶性フィルム中に含有される。酵素粒子は、上に記載される酵素の1つまたは複数を含有してもよい。異なる酵素が、酵素粒子中で混合されまたは隔離され得る(層内への配置など)。
本発明の洗剤パウチは、水溶性フィルムによって形成される区画を含んでなる。水溶性フィルムは、上述されるような酵素粒子を含有する。
(a)水溶性樹脂と、水と、可塑剤以外のあらゆる任意選択の添加剤との混合物を提供するステップと;
(b)混合物を30分間煮沸するステップと;
(c)混合物を少なくとも40℃、任意選択的に例えば、約65℃などの40℃〜70℃の範囲の温度のオーブン内で脱気するステップと;
(d)1つまたは複数の酵素、可塑剤、および追加的な水を65℃以下の温度で混合物に添加するステップと;
(e)混合物が実質的に一様な色と粘稠度に見えるまで、任意選択的に30分間〜90分間の範囲の時間、任意選択的に少なくとも1時間にわたり、ボルテックスなしで混合物を撹拌するステップと;
(f)撹拌時間のすぐ後に(例えば、4時間、または2時間、または1時間以内)に混合物を注入成形するステップ。
a)(上述されるように)第1の区画を形成するステップと;
b)ステップ(a)で形成された閉鎖区画の一部または全部の中に陥凹を形成して、第1の区画上に重畳される第2の成形区画を作成するステップと;
c)第3のフィルムの手段によって、第2の区画を充填して閉鎖するステップと;
d)第1、第2、および第3のフィルムを封止するステップと;
e)フィルムを切断して、多区画パウチを製造するステップと
を含む工程に従って製造されてもよい。
a)任意選択的に加熱および/または真空を使用して、第1のフィルムを第1の成形機上で使用して、第1の区画を形成するステップと;
b)第1の区画を第1の組成物で充填するステップと;
c)任意選択的に加熱および真空を使用して、第2のフィルムを第2の成形機上で変形させて、第2のおよび任意選択的に第3の成形区画を作成するステップと;
d)第2のおよび任意選択的に第3の区画を充填するステップと;
e)第3のフィルムを使用して、第2のおよび任意選択的に第3の区画を封止するステップと;
f)密封された第2のおよび任意選択的に第3の区画を第1の区画に載せるステップと;
g)第1の、第2の、および任意選択的に第3の区画を封止するステップと;
h)フィルムを切断して、多区画パウチを製造するステップと
を含む工程に従って製造されてもよい。
本発明によれば、洗剤組成物は、酵素粒子含有水溶性フィルムによって形成される区画内に含まれる(カプセル化される)。
洗剤組成物は、アニオン性および/またはカチオン性および/または非イオン性および/または半極性および/または両性イオン性、またはその混合物であってもよい、1つまたは複数の界面活性剤を含んでなってもよい。特定の実施形態では、洗剤組成物は、1つまたは複数の非イオン性界面活性剤と、1つまたは複数のアニオン性界面活性剤との混合物を含む。界面活性剤は、典型的に、重量基準で約1%〜約40%、または約3%〜約20%、または約3%〜約10%などの、約0.1%〜60%のレベルで存在する。界面活性剤は、所望の浄化用途に基づいて選択され、当該技術分野で公知のあらゆる従来の界面活性剤が挙げられる。洗剤で使用するために当該技術分野で公知の任意の界面活性剤を利用してもよい。
ヒドロトロープは、疎水性化合物を水溶液に(または逆に、極性物質を非極性環境に)可溶化する化合物である。典型的に、ヒドロトロープは、親水性および疎水性の双方を有する(界面活性剤から知られているようないわゆる両親媒性特性);しかしヒドロトロープの分子構造は、一般に、自発的自己凝集を支援せず、例えばHodgdon and Kaler(2007),Current Opinion in Colloid & Interface Science 12:121−128によるレビューを参照されたい。ヒドロトロープは、ミセル相、ラメラ相またはその他の明確に定義された中間相を形成する、界面活性剤および脂質で見られるような、それを超えると自己凝集が発生する臨界濃度を示さない。その代わりに、多数のヒドロトロープは、濃度の増大に伴って凝集体サイズが大きくなる、連続型凝集過程を示す。しかし、多数のヒドロトロープは、水、油、界面活性剤、およびポリマーの混合物をはじめとする、極性および非極性物質を含有する系の相挙動、安定性、およびコロイド特性を変化させる。ヒドロトロープは、医薬品、パーソナルケア、食品から技術用途に至る産業全体で、古典的に使用されている。洗剤組成物中のヒドロトロープの使用は、相分離または高粘度などの望まれない現象を誘発することなく、(水を除去することで液体洗剤を濃縮する過程のように)例えば界面活性剤のより濃厚な調合物を可能にする。
洗剤組成物は、重量基準で、約5%〜約50%などの、約0〜65%の洗剤ビルダーまたは補助ビルダーまたはその混合物を含有してもよい。食器洗い洗剤中では、ビルダーのレベルは、典型的に40〜65%、特に50〜65%である。ビルダーおよび/または補助ビルダーは、具体的には、CaおよびMgイオンと水溶性複合体を形成するキレート化剤であってもよい。洗濯洗剤で使用するために当該技術分野で公知の任意のビルダーおよび/または補助ビルダーを利用してもよい。ビルダーの非限定的例としては、クエン酸塩、ゼオライト、二リン酸塩(ピロリン酸塩)、三リン酸ナトリウムなどの三リン酸塩(STPまたはSTPP)、炭酸ナトリウムなどの炭酸塩、メタケイ酸ナトリウムなどの可溶性ケイ酸塩、層状ケイ酸塩(例えばヘキスト製のSKS−6)、2−アミノエタン−1−オール(MEA)、ジエタノールアミン(DEA、イミノジエタノールとしてもまた知られている)、トリエタノールアミン(TEA、2,2’,2”−ニトリロトリエタノールとしてもまた知られている)などのエタノールアミン、およびカルボキシメチルイヌリン(CMI)、およびそれらの組み合わせが挙げられる。
洗剤は、重量基準で0.5〜5%、2〜5%、0.5〜2%または0.2〜1%などの、0〜10%のポリマーを含有してもよい。洗剤で使用するために当該技術分野で公知の任意のポリマーを利用してもよい。ポリマーは、上述したような補助ビルダーとして機能してもよく、または再付着防止、繊維保護、防汚、移染防止、グリース浄化および/または消泡特性を提供してもよい。いくつかのポリマーは、上述の特性1つ以上および/または下で言及されるモチーフの1つ以上を有してもよい。代表的なポリマーとしては、(カルボキシメチル)セルロース(CMC)、ポリ(ビニルアルコール)(PVA)、ポリ(ビニルピロリドン)(PVP)、ポリ(エチレングリコール)またはポリ(酸化エチレン)(PEG)、エトキシル化ポリ(エチレンイミン)、カルボキシメチルイヌリン(CMI)、およびPAAなどのポリカルボキシレート、PAA/PMA、ポリアスパラギン酸、およびラウリルメタクリレート/アクリル酸共重合体、疎水性修飾CMC(HM−CMC)およびシリコーン、テレフタル酸とオリゴマーグリコールの共重合体、ポリ(エチレンテレフタレート)とポリ(オキシエテンテレフタレート)の共重合体(PET−POET)、PVP、ポリ(ビニルイミダゾール)(PVI)、ポリ(ビニルピリジン−N−オキシド)(PVPOまたはPVPNO)、およびポリビニルピロリドン−ビニルイミダゾール(PVPVI)が挙げられる。さらなる例示的なポリマーとしては、スルホン化ポリカルボキシレート、ポリエチレンオキシドとポリプロピレンオキシド(PEO−PPO)、およびジクアテルニウムエトキシスルフェートが挙げられる。その他の例示的なポリマーは、例えば、国際公開第2006/130575号パンフレットおよび米国特許第5,955,415号明細書で開示される。上述のポリマーの塩もまた、検討される。
本発明の洗剤組成物は、染料または顔料などの布帛色相付与剤もまた含んでもよく、これは、洗剤組成物に配合されると、前記布帛が、前記洗剤組成物を含んでなる洗浄液に接触した際に、布帛上に沈着し得て、したがって可視光の吸収/反射を通じて前記布帛の色合いを変化させる。蛍光増白剤は、少なくともいくらかの可視光を放出する。対照的に、布帛色相付与剤は、可視光スペクトルの少なくとも一部を吸収して、表面の色合いを変化させる。適切な布帛色相付与剤としては、染料および染料−粘土複合体が挙げられ、顔料もまた挙げられる。適切な染料としては、小分子染料および高分子染料が挙げられる。適切な小分子染料としては、例えば、(参照によって本明細書に援用する)国際公開第2005/03274号パンフレット、国際公開第2005/03275号パンフレット、国際公開第2005/03276号パンフレット、および欧州特許第1876226号明細書に記載されるように、色指数(C.I.)分類で、ダイレクトブルー、ダイレクトレッド、ダイレクトバイオレット、アシッドブルー、アシッドレッド、アシッドバイオレット、ベーシックブルー、ベーシックバイオレット、およびベーシックレッドに分類される染料、またはそれらの混合物からなる群から選択される小分子染料が挙げられる。洗剤組成物は、好ましくは約0.00003重量%〜約0.2重量%、約0.00008重量%〜約0.05重量%、または約0.0001重量%〜約0.04重量%にさえ至る、布帛色相付与剤を含んでなる。組成物は、0.0001重量%〜0.2重量%の布帛色相付与剤を含んでなってもよく、これは、組成物が単位用量パウチの形態である場合に、特に好ましくあってもよい。適切な色相付与剤は、例えば、国際公開第2007/087257号パンフレットおよび国際公開第2007/087243号パンフレットでもまた開示される。
洗剤組成物に含まれてもよい酵素としては、プロテアーゼ、リパーゼ、クチナーゼ、アミラーゼ、カルボヒドラーゼ、セルラーゼ、ペクチナーゼ、マンナナーゼ、アラビナーゼ、ガラクタナーゼ、キシラナーゼ、例えばラッカーゼおよび/またはペルオキシダーゼなどのオキシダーゼなどの1つまたは複数の酵素が挙げられる。これらの酵素の例は、「酵素」セクションで上述される水溶性フィルム中に、酵素粒子として含まれるものと同一である。
洗濯洗剤で使用するために当該技術分野で公知の任意の洗剤成分もまた利用してもよい。その他の任意選択の洗剤成分としては、単独のまたは組み合わせのどちらかでの、抗腐食剤、防縮剤、汚れ再付着防止剤、しわ防止剤、殺菌剤、バインダー、防蝕剤、錠剤分解物質/崩壊剤、染料、酵素安定剤(ホウ酸、ホウ酸塩、CMC、および/またはプロピレングリコールなどのポリオールをはじめとする)、粘土をはじめとする布帛仕上げ剤、増量剤/加工助剤、蛍光性増白剤/光学的増白剤、泡立ち促進剤、泡立ち(泡)調節剤、香料、汚れ懸濁剤、柔軟剤、泡止め剤、変色阻害剤、およびウィッキング剤が挙げられる。洗濯洗剤で使用するために当該技術分野で公知の任意の成分を利用してもよい。このような成分の選択は、十分に当業者の技術範囲内である。
漂白システム本発明の洗剤組成物はまた、漂白システムも含んでもよい。成分の不適合性のために、漂白剤と酵素を組み合わせた液体洗剤は、未だに数例しかない(例えば、米国特許第5,275,753号明細書または国際公開第99/00478号パンフレット)。本発明に記載される酵素粒子を利用して、液体洗剤中の酵素から漂白剤を離隔し得る。洗剤は、0〜50%の漂白系を含有してもよい。洗濯洗剤で使用するために当該技術分野で公知の任意の漂白系を利用してもよい。適切な漂白系成分としては、漂白触媒、光漂白剤、漂白剤活性化剤、過炭酸ナトリウムや過ホウ酸ナトリウムなどの過酸化水素源、予備形成過酸、およびそれらの混合物が挙げられる。適切な予備形成過酸としては、ペルオキシカルボン酸および塩、過炭酸および塩、ペルイミド酸および塩、例えばOxone(登録商標)などのペルオキシ一硫酸および塩、およびそれらの混合物が挙げられるが、これに限定されるものではない。漂白系の非限定的例としては、例えば、過酸形成漂白剤活性化剤と組み合わされた、過ホウ酸のナトリウム塩(通常は、一または四水和物)などのアルカリ金属塩、過炭酸塩、過硫酸塩、過リン酸塩、過ケイ酸塩をはじめとする無機塩を含んでなってもよい、過酸化物ベースの漂白系が挙げられる。漂白剤活性化剤という用語は、本明細書では、過酸化水素のような過酸素漂白剤と反応して、過酸を形成する化合物を意味する。このようにして形成される過酸が、活性化漂白剤を構成する。本明細書で使用される適切な漂白剤活性化剤としては、エステルアミド、イミドまたは無水物のクラスに属するものが挙げられる。適切な例は、テトラアセチルエチレンジアミン(TAED)、ナトリウム−4−[(3,5,5−トリメチルヘキサノイル)オキシ]ベンゼンスルホネート(ISONOBS)、ジペルオキシドデカン酸、4−(ドデカノイルオキシ)ベンゼンスルホネート(LOBS)、4−(デカノイルオキシ)ベンゼンスルホネート、4−(デカノイルオキシ)ベンゾエート(DOBS)、4−(ノナノイルオキシ)−ベンゼンスルホネート(NOBS)、および/または国際公開第98/17767号パンフレットで開示されるものである。関心のある漂白剤活性化剤の特定のファミリーは、欧州特許第624154号明細書で開示され、そのファミリー中で特に好ましいのは、アセチルクエン酸トリエチル(ATC)である。ATC、またはトリアセチンのような短鎖トリグリセリドは、最終的にクエン酸とアルコールに分解するので、環境に優しいという利点を有する。さらにアセチルクエン酸トリエチルおよびトリアセチンは、貯蔵時に製品中で優れた加水分解的安定性を有し、それは効率的な漂白剤活性化剤である。最後にATCは、洗濯添加剤に、優れた助剤能力を提供する。代案としては、漂白系は、例えば、アミド、イミド、またはスルホンタイプのペルオキシ酸を含んでなってもよい。漂白系はまた、6−(フタルイミド)ペルオキシヘキサン酸(PAP)などの過酸を含んでなってもよい。漂白系はまた、漂白剤触媒を含んでもよい。いくつかの実施形態では、漂白剤成分は、式、
本発明の洗剤組成物は、例えば、バー、均質錠剤、2つ以上の層を有する錠剤、1つまたは複数の区画を有するパウチ、通常のまたは緻密型粉末、顆粒、ペースト、ゲル、または通常の、緻密型または濃縮型液体などの任意の便利な形態であってもよい。
本発明は、洗剤組成物を封入するのに有用であり、酵素粒子を含んでなる水溶性フィルムを提供する。酵素粒子は、洗剤組成物との接触時における酵素の貯蔵安定性を改善する。
結晶化リパーゼを含有する水溶性フィルムの改善された貯蔵安定性
次のようにして、国際公開第2013/138288号パンフレットの実施例1に記載されるようにして、(プロテアーゼ、アミラーゼ、およびプロテアーゼ基質なしで)2つの水溶性フィルムが調製された。
注入成形溶液:
・可塑剤および微量の加工助剤を含む2308gのPVA樹脂
・820gのリパーゼ濃縮物(37%固形分溶液)
フィルムは、国際公開第2013/138288号パンフレットの実施例1に記載されるようにして、注入成形され乾燥された。
リパーゼ結晶懸濁液の調製:
フィルムAのために使用されたリパーゼ濃縮物は、限外濾過を使用して数容積の脱イオン水でdia洗浄されて、イオン強度が低下され、引き続いて酢酸でpH5に調節されて、5時間を超えて放冷されて結晶化された(リパーゼを結晶化させるためには低イオン強度およびpH5が好ましい)。
・可塑剤および微量の加工助剤を含む2308gのPVA樹脂
・820gのリパーゼ結晶懸濁液(37%固形分)
フィルムは、国際公開第2013/138288号パンフレットの実施例1に記載されるようにして、注入成形され乾燥された。
リパーゼ含有水溶性フィルムの製造後のリパーゼ活性の回復は、リパーゼ濃縮物(フィルムA)を使用した場合よりも、リパーゼ結晶懸濁液(フィルムB)を使用した場合により高かった。リパーゼ活性の回復は、フィルムAの製造後よりもフィルムBの製造後に29%高かった。フィルムAは、フィルムB中のリパーゼ回復と比較して77%のみのリパーゼ回復を有した。
小さなフィルムシートが閉鎖型ガラスバイアルに入れられて、表に記載される温度で4週間貯蔵された。貯蔵後、リパーゼ活性が測定されて、−18℃の冷凍庫内で貯蔵されたサンプルとの比較で残効性が計算された。データは、表1に示される。
小さなフィルムシートが、2013年に米国で購入された市販のTide Podsの不透明な白色液体に浸漬されて、閉鎖型ガラスバイアルに入れられた。バイアルを30℃で2週間貯蔵した。貯蔵後、リパーゼ活性が測定されて、−18℃の冷凍庫内で貯蔵されたサンプルとの比較で残効性が計算された。データは、表2に示される。
Claims (12)
- 酵素粒子がフィルム中に存在する水溶性フィルムによって形成される区画と、当該区画内に界面活性剤および/または洗剤ビルダーを含有する液体洗剤組成物とを含んでなる、合成洗剤パウチであって、前記酵素粒子が酵素結晶であり、酵素粒子径が0.5μm〜100μmである、前記合成洗剤パウチ。
- 前記洗剤組成物が、洗濯または食器洗い洗剤組成物である、請求項1に記載の洗剤パウチ。
- 前記酵素が、プロテアーゼ、メタロプロテアーゼ、サブチリシン、リパーゼ、クチナーゼ、アミラーゼ、カルボヒドラーゼ、セルラーゼ、ペクチナーゼ、マンナナーゼ、アラビナーゼ、ガラクタナーゼ、キシラナーゼ、キサンタナーゼ、DNAse、ラッカーゼ、ペルオキシダーゼ、オキシダーゼ、ハロペルオキシダーゼ、ペルヒドロラーゼ、およびそれらの組み合わせからなる群から選択される、請求項1又は2に記載の洗剤パウチ。
- 前記酵素が、リパーゼである、請求項1〜3のいずれか一項に記載の洗剤パウチ。
- 前記水溶性フィルムが、75%〜99%の加水分解度を有する、35%〜90%のPVOHを含んでなる、請求項1〜4のいずれか一項に記載の洗剤パウチ。
- 前記水溶性フィルムが、10%〜50%のポリオールを含んでなる、請求項1〜5のいずれか一項に記載の洗剤パウチ。
- 前記水溶性フィルムの厚さが、10μm〜500μmである、請求項1〜6のいずれか一項に記載の洗剤パウチ。
- 洗剤組成物を酵素粒子を含んでなる水溶性フィルムで封入するステップを含んでなる、請求項1〜7のいずれか一項に記載の洗剤パウチを調製する方法。
- 前記洗剤組成物が、液体洗剤組成物である、請求項8に記載の方法。
- 洗剤組成物を封入するための、酵素粒子を含んでなる水溶性フィルムであって、酵素粒子が酵素結晶であり、酵素粒子径が0.5μm〜100μmである、前記水溶性フィルム。
- 請求項1〜7のいずれか一項に記載の洗剤パウチ内の酵素の貯蔵安定性を改善するための、請求項10に記載の水溶性フィルムの使用。
- 酵素粒子を液体フィルム組成物に添加するステップと、前記水溶性フィルムを注入成形するステップとを含んでなる、請求項10に記載の水溶性フィルムの製造中に酵素活性の損失を低下させ、または回復を改善する方法。
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KR20170072774A (ko) | 2015-12-17 | 2017-06-27 | 주식회사 엘지생활건강 | 기능성 과립을 포함하는 세탁용 시트 |
US10927331B2 (en) | 2017-02-14 | 2021-02-23 | Sutherland Products, Inc. | Dissolvable detergent pouch and method |
WO2019035044A1 (en) * | 2017-08-18 | 2019-02-21 | The Procter & Gamble Company | CLEANING METHOD |
CA3071086A1 (en) * | 2017-08-18 | 2019-02-21 | The Procter & Gamble Company | Cleaning agent |
EP3831878B1 (en) * | 2018-07-31 | 2022-05-04 | Mitsubishi Chemical Corporation | Polyvinyl alcohol film and chemical agent package |
CN113330101A (zh) * | 2018-12-21 | 2021-08-31 | 诺维信公司 | 包含金属蛋白酶的洗涤剂袋 |
US11125047B1 (en) | 2019-01-07 | 2021-09-21 | Workover Solutions, Inc. | Dissolvable diversion package and method of use |
US11939610B2 (en) * | 2020-09-16 | 2024-03-26 | NeoGeneStar LLC | Protease compositions and methods of use thereof |
US20230374416A1 (en) * | 2022-05-23 | 2023-11-23 | CW ECO Solutions Inc. | Drain cleaner |
Family Cites Families (15)
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US4176079A (en) * | 1977-04-20 | 1979-11-27 | The Procter & Gamble Company | Water-soluble enzyme-containing article |
US4115292A (en) * | 1977-04-20 | 1978-09-19 | The Procter & Gamble Company | Enzyme-containing detergent articles |
ES2044718T3 (es) * | 1989-12-21 | 1994-01-01 | Novo Nordisk As | Preparacion que contiene enzimas y detergente que contiene dicha preparacion. |
DE4319908A1 (de) * | 1993-06-16 | 1994-12-22 | Solvay Enzymes Gmbh & Co Kg | Flüssige Enzymzubereitungen |
US5753152A (en) * | 1995-09-06 | 1998-05-19 | Lever Brothers Company, Division Of Conopco, Inc. | Process for making polymer matrix capsules containing large hydrocarbon drops suitable for incorporating large size actives to be used in liquid detergent compositions |
US7595290B2 (en) * | 2000-04-28 | 2009-09-29 | The Procter & Gamble Company | Water-soluble stretchable pouches containing compositions |
AU2001294902A1 (en) * | 2000-09-28 | 2002-04-08 | The Dow Chemical Company | Polymer composite structures useful for controlled release systems |
DE10053329A1 (de) * | 2000-10-27 | 2002-05-08 | Henkel Kgaa | Enzymhaltige Umhüllung für Waschmittel-, Spülmittel- oder Reinigungsmittel-Portionen |
ES2344407T3 (es) * | 2001-10-09 | 2010-08-26 | Arrow Coated Products Limited | Procedimiento de fabricacion de un sistema de pelicula soluble en el agua embebida. |
US7368273B2 (en) * | 2002-03-22 | 2008-05-06 | Kao Corporation | Alkaline protease |
GB2442626A (en) * | 2005-06-16 | 2008-04-09 | Nippon Synthetic Chem Ind | Water-soluble film |
US8066818B2 (en) * | 2008-02-08 | 2011-11-29 | The Procter & Gamble Company | Water-soluble pouch |
EP2480649A1 (en) * | 2009-09-25 | 2012-08-01 | Novozymes A/S | Detergent composition |
EP2831215B1 (en) * | 2012-03-29 | 2018-08-08 | Novozymes A/S | Use of enzymes for preparing water soluble films |
US9394092B2 (en) * | 2012-04-16 | 2016-07-19 | Monosol, Llc | Powdered pouch and method of making same |
-
2014
- 2014-12-10 JP JP2016539033A patent/JP6615758B2/ja active Active
- 2014-12-10 EP EP14825275.2A patent/EP3080195B1/en active Active
- 2014-12-10 WO PCT/EP2014/077251 patent/WO2015086692A1/en active Application Filing
- 2014-12-10 US US15/102,750 patent/US20160312157A1/en not_active Abandoned
- 2014-12-10 KR KR1020167017449A patent/KR20160103009A/ko not_active Application Discontinuation
- 2014-12-10 CN CN201480067258.1A patent/CN106029752A/zh active Pending
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JP2017502127A (ja) | 2017-01-19 |
KR20160103009A (ko) | 2016-08-31 |
WO2015086692A1 (en) | 2015-06-18 |
CN106029752A (zh) | 2016-10-12 |
US20160312157A1 (en) | 2016-10-27 |
EP3080195B1 (en) | 2019-04-10 |
EP3080195A1 (en) | 2016-10-19 |
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