JP5956078B2 - ペシロマイセス・バリオティ・バラエティ・ブルンネオラスgpp1101b菌株及びこれを用いた製剤 - Google Patents
ペシロマイセス・バリオティ・バラエティ・ブルンネオラスgpp1101b菌株及びこれを用いた製剤 Download PDFInfo
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Description
前記培養液の製造方法において、前記培養を終えた後、肥大成長した前記菌株をろ過して培養ろ液を製造してもよい。
2)K:Compound K.(コンパウンド−K)
3)PPD:Protopanaxadiol.(プロトパナキサジオール)
Claims (17)
- 人参の発酵過程で分離されるペシロマイセス・バリオティ・バラエティ・ブルンネオラス(Paecilomyces variotii var. brunneolus)GPP1101B(微生物寄託番号KCTC11993BP)の菌株。
- 請求項1に記載のペシロマイセス・バリオティ・バラエティ・ブルンネオラス(Paecilomyces variotii var. brunneolus)GPP1101B(微生物寄託番号KCTC11993BP)の菌株を人参又は紅参のエキスに投入して培養された培養液を含有することを特徴とする免疫活性剤の製造方法。
- 前記培養液は、肥大成長した前記菌株をろ過した培養ろ液であることを特徴とする請求項2に記載の免疫活性剤の製造方法。
- 前記培養液を凍結乾燥して含有することを特徴とする請求項2又は請求項3記載の免疫活性剤の製造方法。
- 請求項1に記載のペシロマイセス・バリオティ・バラエティ・ブルンネオラス(Paecilomyces variotii var. brunneolus)GPP1101B(微生物寄託番号KCTC11993BP)の菌株を人参又は紅参のエキスに投入して培養された培養液を含有することを特徴とする抗菌活性剤の製造方法。
- 前記培養液は、肥大成長した前記菌株をろ過した培養ろ液であることを特徴とする請求項5に記載の抗菌活性剤の製造方法。
- 前記培養液を凍結乾燥して含有することを特徴とする請求項5又は請求項6記載の抗菌活性剤の製造方法。
- 請求項1記載のペシロマイセス・バリオティ・バラエティ・ブルンネオラス(Paecilomyces variotii var. brunneolus)GPP1101B(微生物寄託番号KCTC11993BP)の菌株を人参又は紅参のエキスに投入して培養された培養ろ液を含有することを特徴とする抗癌剤の製造方法。
- 前記培養ろ液は、肥大成長した前記菌株をろ過した培養ろ液であることを特徴とする請求項8に記載の抗癌剤の製造方法。
- 前記培養ろ液を凍結乾燥して含有することを特徴とする請求項8又は請求項9記載の抗癌剤の製造方法。
- 請求項1に記載のペシロマイセス・バリオティ・バラエティ・ブルンネオラス(Paecilomyces variotii var. brunneolus)GPP1101B(微生物寄託番号KCTC11993BP)の菌株を人参又は紅参のエキスに投入して培養された培養ろ液を含有することを特徴とする抗突然変異剤の製造方法。
- 前記培養ろ液は、肥大成長した前記菌株をろ過した培養ろ液であることを特徴とする請求項11記載の抗突然変異剤の製造方法。
- 前記培養ろ液を凍結乾燥して含有することを特徴とする請求項11又は請求項12記載の抗突然変異剤の製造方法。
- 請求項1に記載のペシロマイセス・バリオティ・バラエティ・ブルンネオラス(Paecilomyces variotii var. brunneolus)GPP1101B(微生物寄託番号KCTC11993BP)の菌株を人参又は紅参のエキスに投入して培養することを特徴とする培養液の製造方法。
- 前記人参又は紅参のエキスは、人参または紅参を水に入れて60〜100℃の温度において12〜72時間加熱し、人参または紅参をろ過した溶液であることを特徴とする請求項14記載の培養液の製造方法。
- 前記培養は、前記菌株を投入した前記人参又は紅参のエキスを、培養器を用いて15〜35℃の温度において10〜60日間行うことを特徴とする請求項14に記載の培養液の製造方法。
- 前記培養の後、肥大成長した前記菌株をろ過して培養ろ液を製造することを特徴とする請求項14乃至請求項16のうちいずれか一項記載の培養液の製造方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020120098759A KR101434741B1 (ko) | 2012-09-06 | 2012-09-06 | 페실로마이세스 바리오티 바라이어티 브른네오러스 gpp1101b 균주 및 이를 이용한 제제 |
KR10-2012-0098759 | 2012-09-06 | ||
PCT/KR2013/007897 WO2014038822A1 (ko) | 2012-09-06 | 2013-09-02 | 페실로마이세스 바리오티 바라이어티 브른네오러스 gpp1101b 균주 및 이를 이용한 제제 |
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JP2015529079A JP2015529079A (ja) | 2015-10-05 |
JP5956078B2 true JP5956078B2 (ja) | 2016-07-20 |
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JP2015531003A Expired - Fee Related JP5956078B2 (ja) | 2012-09-06 | 2013-09-02 | ペシロマイセス・バリオティ・バラエティ・ブルンネオラスgpp1101b菌株及びこれを用いた製剤 |
Country Status (6)
Country | Link |
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US (1) | US9610312B2 (ja) |
EP (1) | EP2902480B1 (ja) |
JP (1) | JP5956078B2 (ja) |
KR (1) | KR101434741B1 (ja) |
CN (1) | CN104736692B (ja) |
WO (1) | WO2014038822A1 (ja) |
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KR101970702B1 (ko) * | 2016-06-23 | 2019-04-22 | 천부협동조합 | 생물전환 기술을 이용한 발효 삼 조성물 및 이의 제조방법 |
CN107898833A (zh) * | 2017-12-15 | 2018-04-13 | 浙江海洋大学 | 一种大黄鱼非特异性免疫刺激剂 |
KR102172224B1 (ko) * | 2018-12-28 | 2020-10-30 | 건국대학교 글로컬산학협력단 | 인삼 발효 추출물을 유효성분으로 함유하여 황색포도상구균에 대한 항균 활성을 갖는 조성물 |
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KR0144130B1 (ko) | 1993-12-17 | 1998-07-15 | 신재인 | 면역증강 효과가 있는 인삼다당체("진산") |
US6555527B1 (en) | 1999-08-27 | 2003-04-29 | Korea Atomic Energy Research Institute | Hematopoietic, myeloprotecting, antitumor immune cells generating and radiosensitizing polysaccharide isolated from Panax ginseng |
KR100475131B1 (ko) | 2001-11-02 | 2005-03-08 | 한국생명공학연구원 | 신규한 패실로마이세스 속 미생물 및 그를 포함하는 토양해충 방제용 미생물 살충제 |
KR101361061B1 (ko) | 2007-04-09 | 2014-02-07 | 삼성전자주식회사 | 서버/클라이언트 네트워크에서의 효율적인 정보 전송 방법및 이를 이용한 서버 장치와 클라이언트 장치 |
CN101165166B (zh) * | 2007-10-10 | 2010-08-25 | 首都师范大学 | 热带假丝酵母的新用途 |
KR20090083505A (ko) * | 2008-01-30 | 2009-08-04 | 주식회사 바이오랜드 | 락토바실러스 퍼멘텀 bljh101을 이용한인삼추출물의 발효물을 제조하는 방법 및 이를 함유하는조성물 |
KR101163986B1 (ko) | 2009-04-22 | 2012-07-09 | 한국화학연구원 | 바실러스 벨레젠시스 g341 균주 및 이를 이용한 식물병 방제방법 |
KR20110098122A (ko) * | 2010-02-26 | 2011-09-01 | (주)아모레퍼시픽 | 균을 이용한 인삼 열매 발효 추출물을 함유하는 조성물 |
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2012
- 2012-09-06 KR KR1020120098759A patent/KR101434741B1/ko active IP Right Grant
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2013
- 2013-09-02 JP JP2015531003A patent/JP5956078B2/ja not_active Expired - Fee Related
- 2013-09-02 EP EP13835795.9A patent/EP2902480B1/en not_active Not-in-force
- 2013-09-02 WO PCT/KR2013/007897 patent/WO2014038822A1/ko active Application Filing
- 2013-09-02 US US14/426,548 patent/US9610312B2/en not_active Expired - Fee Related
- 2013-09-02 CN CN201380046501.7A patent/CN104736692B/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
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WO2014038822A1 (ko) | 2014-03-13 |
CN104736692A (zh) | 2015-06-24 |
KR20140032182A (ko) | 2014-03-14 |
CN104736692B (zh) | 2017-07-21 |
KR101434741B1 (ko) | 2014-08-29 |
US9610312B2 (en) | 2017-04-04 |
EP2902480A1 (en) | 2015-08-05 |
EP2902480B1 (en) | 2017-11-08 |
JP2015529079A (ja) | 2015-10-05 |
EP2902480A4 (en) | 2016-04-27 |
US20150224156A1 (en) | 2015-08-13 |
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