JP5758295B2 - 病理グロシングツール、カセットおよびボード - Google Patents
病理グロシングツール、カセットおよびボード Download PDFInfo
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- JP5758295B2 JP5758295B2 JP2011524991A JP2011524991A JP5758295B2 JP 5758295 B2 JP5758295 B2 JP 5758295B2 JP 2011524991 A JP2011524991 A JP 2011524991A JP 2011524991 A JP2011524991 A JP 2011524991A JP 5758295 B2 JP5758295 B2 JP 5758295B2
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- 238000005520 cutting process Methods 0.000 claims description 41
- 230000001575 pathological effect Effects 0.000 claims description 26
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- 238000000465 moulding Methods 0.000 claims description 2
- 238000012545 processing Methods 0.000 description 11
- 239000000243 solution Substances 0.000 description 11
- 239000004033 plastic Substances 0.000 description 9
- 229920003023 plastic Polymers 0.000 description 9
- 238000007373 indentation Methods 0.000 description 7
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- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
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- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000012735 histological processing Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 229910001369 Brass Inorganic materials 0.000 description 1
- 229910001339 C alloy Inorganic materials 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 229910000640 Fe alloy Inorganic materials 0.000 description 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 229960000583 acetic acid Drugs 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 239000010951 brass Substances 0.000 description 1
- 239000007975 buffered saline Substances 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
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- 239000002480 mineral oil Substances 0.000 description 1
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- 238000002360 preparation method Methods 0.000 description 1
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- 102000004169 proteins and genes Human genes 0.000 description 1
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Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Description
本願は、2008年8月27日出願の仮特許出願番号61/136,316の権益を主張する。
Claims (12)
- スペーサー無しで提供される組織カセットであり:
(i) 組織サンプルを受容するのに適合するチャンバを画定する側壁と底壁とを含むベース:ならびに
(ii) 前記ベースにもたらされ、前記組織サンプルを前記チャンバ内に残すために前記チャンバを覆うよう適合する、蓋;
を含有し、
ここで前記ベースの前記底壁が、0.5mmから3mmの範囲のチャンバの深さをもたらすよう前記側壁に対して配置され、そして前記ベースがグロシングツールもしくはグロシングボードに配置され、かつ刃が切断表面に沿って組織を通って引かれるときに、組織サンプルをチャンバの深さの厚さに切断する切断の刃のための切断表面を、前記側壁の前記底壁が配置されている側とは反対側の面が提供する、組織カセット。 - 前記チャンバの深さが2.5mmから3mmの範囲である、請求項1に記載の組織カセット。
- 前記チャンバの深さが3mmである、請求項1に記載の組織カセット。
- 前記チャンバの深さが0.5mmから2.5mmの範囲である、請求項1に記載の組織カセット。
- 前記チャンバの深さが1.5mmである、請求項1に記載の組織カセット。
- 前記チャンバの深さが0.5mmから1.0mmの範囲である、請求項1に記載の組織カセット。
- 前記チャンバの深さが0.5mmである、請求項1に記載の組織カセット。
- 前記蓋が***する頂部壁を含む、請求項1〜7のいずれか一項に記載の組織カセット。
- 前記蓋の前記頂部壁が、蓋ベースより約1mm***する、請求項8に記載の組織カセット。
- 前記ベースおよび蓋が成型によって作製される、請求項1〜9のいずれか一項に記載の組織カセット。
- 病理グロシングボードであって:
(i)請求項1〜10のいずれか一項に記載の組織カセットのベースと適合するようにされた一つもしくはそれ以上のカセット受容くぼみ;ならびに
(ii)ナイフもしくは外科用メスの刃を前記カセット受容くぼみ中のベースに沿って誘導するための、一つもしくはそれ以上のカセット受容くぼみの反対側に備えられる刃ガイドを含有する、
病理グロシングボード。 - 蓋の反対の端が、ベースに備えられる穴とかみ合わされるためのクリップを含む、請求項1〜10のいずれか一項に記載の組織カセット。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13631608P | 2008-08-27 | 2008-08-27 | |
US61/136,316 | 2008-08-27 | ||
PCT/US2009/004850 WO2010027430A2 (en) | 2008-08-27 | 2009-08-26 | Pathology grossing tool, cassette, and board |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015000261A Division JP5964998B2 (ja) | 2008-08-27 | 2015-01-05 | 病理グロシングツール、カセットおよびボード |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2012501441A JP2012501441A (ja) | 2012-01-19 |
JP5758295B2 true JP5758295B2 (ja) | 2015-08-05 |
Family
ID=41797710
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011524991A Active JP5758295B2 (ja) | 2008-08-27 | 2009-08-26 | 病理グロシングツール、カセットおよびボード |
JP2015000261A Active JP5964998B2 (ja) | 2008-08-27 | 2015-01-05 | 病理グロシングツール、カセットおよびボード |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015000261A Active JP5964998B2 (ja) | 2008-08-27 | 2015-01-05 | 病理グロシングツール、カセットおよびボード |
Country Status (6)
Country | Link |
---|---|
US (1) | US20110008884A1 (ja) |
EP (1) | EP2316010B1 (ja) |
JP (2) | JP5758295B2 (ja) |
DK (1) | DK2316010T3 (ja) |
ES (1) | ES2909653T3 (ja) |
WO (1) | WO2010027430A2 (ja) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
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US9217696B2 (en) * | 2011-09-29 | 2015-12-22 | The University Of Miami | Ultra-rapid diagnostic tissue preparation as an alternative to frozen section |
ES2832554T3 (es) | 2012-06-22 | 2021-06-10 | Leica Biosystems Nussloch Gmbh | Recipiente para muestras de tejido |
CA2876682A1 (en) | 2012-06-22 | 2013-12-27 | Leica Biosystems Nussloch Gmbh | Biopsy tissue sample transport device and method of using thereof |
CA2845832C (en) | 2013-03-15 | 2020-09-22 | Leica Biosystems Nussloch Gmbh | Tissue cassette with biasing element |
US9052256B2 (en) * | 2013-03-15 | 2015-06-09 | Leica Biosystems Nussloch Gmbh | Method for processing and embedding tissue |
CA2845830C (en) | 2013-03-15 | 2020-10-27 | Leica Biosystems Nussloch Gmbh | Tissue cassette with retractable member |
US9984457B2 (en) | 2014-03-26 | 2018-05-29 | Sectra Ab | Automated grossing image synchronization and related viewers and workstations |
US10839509B2 (en) | 2015-07-10 | 2020-11-17 | 3Scan Inc. | Spatial multiplexing of histological stains |
JP2017138152A (ja) * | 2016-02-02 | 2017-08-10 | 村角工業株式会社 | 医療検査用カセット |
US10489633B2 (en) | 2016-09-27 | 2019-11-26 | Sectra Ab | Viewers and related methods, systems and circuits with patch gallery user interfaces |
WO2018067407A1 (en) * | 2016-10-03 | 2018-04-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Module for freezing and storage of frozen tissue |
WO2018066658A1 (ja) * | 2016-10-07 | 2018-04-12 | 株式会社ウミヒラ | 組織分割用治具 |
JP7405690B2 (ja) * | 2020-05-18 | 2023-12-26 | 株式会社堀場テクノサービス | 分析面切削用治具、分析装置、分析面切削方法、及び分析方法 |
Family Cites Families (41)
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JPS5926032A (ja) * | 1982-01-12 | 1984-02-10 | インバレスク・リサ−チ・インタ−ナシヨナル・リミテツド | 生物組織カセツト |
US4623308A (en) * | 1984-04-16 | 1986-11-18 | Maclean-Fogg Company | Free standing base mold |
US4549670A (en) * | 1984-12-19 | 1985-10-29 | Maclean-Fogg Company | Hinged tissue cassette apparatus |
GB2189596B (en) | 1986-04-16 | 1990-08-01 | Pa Consulting Services | Methods of and apparatus for preparing tissue specimens |
JPH0219494U (ja) * | 1988-07-19 | 1990-02-08 | ||
JP2547385Y2 (ja) * | 1990-11-07 | 1997-09-10 | 村▼ずみ▲工業株式会社 | 医療検査用カセット |
US5127537A (en) * | 1991-06-05 | 1992-07-07 | Graham Donald R | Tissue cassette with a living hinge |
US5269671A (en) * | 1992-02-11 | 1993-12-14 | Mccormick James B | Apparatus for embedding tissue samples |
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US7138226B2 (en) | 2002-05-10 | 2006-11-21 | The University Of Miami | Preservation of RNA and morphology in cells and tissues |
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BR0215894B1 (pt) * | 2002-09-26 | 2012-11-27 | cassete de retenção de amostra de tecido, montagem para embutir amostra de tecido antes do procedimento de microtomia, dispositivo de escalonamento de cassete de amostra de tecido e método de corte de cassete. | |
ES2401865T3 (es) * | 2002-09-26 | 2013-04-25 | Biopath Automation, L.L.C. | Aparato y procedimientos para la manipulación automatizada e incorporación de muestras de tejido |
US7179424B2 (en) * | 2002-09-26 | 2007-02-20 | Biopath Automation, L.L.C. | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
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-
2009
- 2009-08-26 JP JP2011524991A patent/JP5758295B2/ja active Active
- 2009-08-26 EP EP09811808.6A patent/EP2316010B1/en active Active
- 2009-08-26 ES ES09811808T patent/ES2909653T3/es active Active
- 2009-08-26 DK DK09811808.6T patent/DK2316010T3/da active
- 2009-08-26 WO PCT/US2009/004850 patent/WO2010027430A2/en active Application Filing
- 2009-08-26 US US12/919,200 patent/US20110008884A1/en not_active Abandoned
-
2015
- 2015-01-05 JP JP2015000261A patent/JP5964998B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
EP2316010A2 (en) | 2011-05-04 |
WO2010027430A3 (en) | 2010-06-17 |
DK2316010T3 (da) | 2022-03-28 |
JP2012501441A (ja) | 2012-01-19 |
EP2316010A4 (en) | 2017-11-15 |
EP2316010B1 (en) | 2022-03-16 |
WO2010027430A2 (en) | 2010-03-11 |
JP5964998B2 (ja) | 2016-08-03 |
US20110008884A1 (en) | 2011-01-13 |
ES2909653T3 (es) | 2022-05-09 |
JP2015092179A (ja) | 2015-05-14 |
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