JP5689817B2 - 酢酸クロルヘキシジン消毒洗浄剤 - Google Patents
酢酸クロルヘキシジン消毒洗浄剤 Download PDFInfo
- Publication number
- JP5689817B2 JP5689817B2 JP2011545368A JP2011545368A JP5689817B2 JP 5689817 B2 JP5689817 B2 JP 5689817B2 JP 2011545368 A JP2011545368 A JP 2011545368A JP 2011545368 A JP2011545368 A JP 2011545368A JP 5689817 B2 JP5689817 B2 JP 5689817B2
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- JP
- Japan
- Prior art keywords
- cleaning agent
- chlorhexidine acetate
- alcohol
- weight
- isopropanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 title claims description 53
- 229960002152 chlorhexidine acetate Drugs 0.000 title claims description 51
- 239000000645 desinfectant Substances 0.000 title claims description 11
- 239000012459 cleaning agent Substances 0.000 claims description 134
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 80
- 239000000463 material Substances 0.000 claims description 46
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 43
- 239000002250 absorbent Substances 0.000 claims description 32
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- 239000003139 biocide Substances 0.000 claims description 26
- 239000000126 substance Substances 0.000 claims description 15
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims description 11
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- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
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- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 5
- 229960003333 chlorhexidine gluconate Drugs 0.000 description 5
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- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 2
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- AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 description 2
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- 229960003260 chlorhexidine Drugs 0.000 description 2
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- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
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- MYPYJXKWCTUITO-LYRMYLQWSA-O vancomycin(1+) Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C([O-])=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)[NH2+]C)[C@H]1C[C@](C)([NH3+])[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-O 0.000 description 2
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- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 1
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- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
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- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
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- WDRFFJWBUDTUCA-UHFFFAOYSA-N chlorhexidine acetate Chemical compound CC(O)=O.CC(O)=O.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WDRFFJWBUDTUCA-UHFFFAOYSA-N 0.000 description 1
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- JEGUKCSWCFPDGT-UHFFFAOYSA-N h2o hydrate Chemical compound O.O JEGUKCSWCFPDGT-UHFFFAOYSA-N 0.000 description 1
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 1
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Images
Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
- C11D7/26—Organic compounds containing oxygen
- C11D7/261—Alcohols; Phenols
- C11D7/262—Alcohols; Phenols fatty or with at least 8 carbon atoms in the alkyl or alkenyl chain
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
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- C—CHEMISTRY; METALLURGY
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/50—Solvents
- C11D7/5004—Organic solvents
- C11D7/5022—Organic solvents containing oxygen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
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- C—CHEMISTRY; METALLURGY
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
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Description
Claims (9)
- 消毒洗浄剤において、
酢酸クロルヘキシジンを含む第1の非アルコール性の殺生物剤であって、該酢酸クロルヘキシジンが、前記洗浄剤の0.01重量%から10重量%までを構成する第1の非アルコール性の殺生物剤と、
イソプロパノールおよびエタノールを含むアルコールであって、該イソプロパノールのエタノールに対する比率が、1:3と1:1との間にあるアルコールと、を含み、
前記洗浄剤が、5−クロロ−2−(2,4−ジクロロフェノキシ)フェノールをさらに含み、
前記消毒洗浄剤が乾燥した場合、非粘着性の堆積物を塗布した表面に形成する消毒洗浄剤。 - 前記アルコールが、前記洗浄剤の90重量%を超えて含む請求項1に記載の消毒洗浄剤。
- 前記5−クロロ−2−(2,4−ジクロロフェノキシ)フェノールが、洗浄剤の0.01重量%から10重量%までを構成する請求項1に記載の消毒洗浄剤。
- 消毒洗浄剤において、
酢酸クロルヘキシジンと、
酢酸クロルヘキシジンを溶解可能なイソプロパノールおよびエタノールを含むアルコールであって、該イソプロパノールのエタノールに対する比率が、1:3と1:1との間にあるアルコールと、
吸収材とを含み、
前記吸収材は、前記洗浄剤で含浸され、
前記洗浄剤が、5−クロロ−2−(2,4−ジクロロフェノキシ)フェノールをさらに含み、
前記洗浄剤は、該洗浄剤が乾燥した場合、非粘着性の堆積物を塗布した表面に形成する消毒洗浄剤。 - 前記溶媒が、前記洗浄剤の90重量%を超えてを占めるアルコールを含む請求項4に記載の洗浄剤。
- 前記溶媒が、洗浄剤の90.1重量%を超えて構成する水を含む請求項4に記載の洗浄剤。
- 前記洗浄剤の0.01重量%から10重量%までを構成する5−クロロ−2−(2,4−ジクロロフェノキシ)フェノールを含む請求項4に記載の洗浄剤。
- 前記吸収材が、カチオン性または非イオン性物質を含む請求項4に記載の洗浄剤。
- カチオン性または非イオン性物質が、ポリエステル、ポリプロピレン、カチオン性界面活性剤で被覆された綿、およびシリコーンから選択される請求項8に記載の洗浄剤。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US12/349,347 US7704935B1 (en) | 2009-01-06 | 2009-01-06 | Chlorhexidine acetate antiseptic cleaning agent |
US12/349,347 | 2009-01-06 | ||
PCT/US2009/069209 WO2010080652A1 (en) | 2009-01-06 | 2009-12-22 | Chlorhexidine acetate antiseptic cleaning agent |
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JP2012514641A5 JP2012514641A5 (ja) | 2013-02-07 |
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EP (1) | EP2376129A1 (ja) |
JP (1) | JP5689817B2 (ja) |
CN (2) | CN102316906A (ja) |
AU (1) | AU2009335672B2 (ja) |
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EP2376129A1 (en) | 2011-10-19 |
US7704935B1 (en) | 2010-04-27 |
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