JP2012514641A - 酢酸クロルヘキシジン消毒洗浄剤 - Google Patents
酢酸クロルヘキシジン消毒洗浄剤 Download PDFInfo
- Publication number
- JP2012514641A JP2012514641A JP2011545368A JP2011545368A JP2012514641A JP 2012514641 A JP2012514641 A JP 2012514641A JP 2011545368 A JP2011545368 A JP 2011545368A JP 2011545368 A JP2011545368 A JP 2011545368A JP 2012514641 A JP2012514641 A JP 2012514641A
- Authority
- JP
- Japan
- Prior art keywords
- cleaning agent
- chlorhexidine acetate
- alcohol
- isopropanol
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 title claims abstract description 57
- 229960002152 chlorhexidine acetate Drugs 0.000 title claims abstract description 55
- 239000000645 desinfectant Substances 0.000 title claims abstract description 10
- 239000012459 cleaning agent Substances 0.000 claims abstract description 142
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 86
- 239000000463 material Substances 0.000 claims abstract description 49
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims abstract description 47
- 239000002250 absorbent Substances 0.000 claims abstract description 34
- 230000002745 absorbent Effects 0.000 claims abstract description 34
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- 239000003599 detergent Substances 0.000 claims abstract description 28
- 230000003115 biocidal effect Effects 0.000 claims abstract description 27
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims abstract description 11
- -1 polypropylene Polymers 0.000 claims abstract description 10
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- 150000001298 alcohols Chemical class 0.000 abstract description 15
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- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 241000191967 Staphylococcus aureus Species 0.000 description 5
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 5
- 229960003333 chlorhexidine gluconate Drugs 0.000 description 5
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- 239000004615 ingredient Substances 0.000 description 5
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 4
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- VVJKKWFAADXIJK-UHFFFAOYSA-N Allylamine Chemical compound NCC=C VVJKKWFAADXIJK-UHFFFAOYSA-N 0.000 description 2
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 description 2
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 2
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- 108010059993 Vancomycin Proteins 0.000 description 2
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- 239000007864 aqueous solution Substances 0.000 description 2
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- ZSIAUFGUXNUGDI-UHFFFAOYSA-N hexan-1-ol Chemical compound CCCCCCO ZSIAUFGUXNUGDI-UHFFFAOYSA-N 0.000 description 2
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- 150000003077 polyols Chemical class 0.000 description 2
- 229920001451 polypropylene glycol Polymers 0.000 description 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
- 239000008213 purified water Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
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- 229960003165 vancomycin Drugs 0.000 description 2
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 2
- MYPYJXKWCTUITO-LYRMYLQWSA-O vancomycin(1+) Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C([O-])=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)[NH2+]C)[C@H]1C[C@](C)([NH3+])[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-O 0.000 description 2
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- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 1
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- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
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- WDRFFJWBUDTUCA-UHFFFAOYSA-N chlorhexidine acetate Chemical compound CC(O)=O.CC(O)=O.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WDRFFJWBUDTUCA-UHFFFAOYSA-N 0.000 description 1
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- JEGUKCSWCFPDGT-UHFFFAOYSA-N h2o hydrate Chemical compound O.O JEGUKCSWCFPDGT-UHFFFAOYSA-N 0.000 description 1
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
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- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
- C11D17/04—Detergent materials or soaps characterised by their shape or physical properties combined with or containing other objects
- C11D17/049—Cleaning or scouring pads; Wipes
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
- C11D7/26—Organic compounds containing oxygen
- C11D7/261—Alcohols; Phenols
- C11D7/262—Alcohols; Phenols fatty or with at least 8 carbon atoms in the alkyl or alkenyl chain
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
- C11D7/22—Organic compounds
- C11D7/28—Organic compounds containing halogen
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
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- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
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- A61L2202/24—Medical instruments, e.g. endoscopes, catheters, sharps
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
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Abstract
Description
Claims (12)
- 消毒洗浄剤において、
酢酸クロルヘキシジンを含む第1の非アルコール性の殺生物剤であって、該酢酸クロルヘキシジンが、前記洗浄剤の約0.01重量%から約10重量%までを構成する第1の非アルコール性の殺生物剤と、
イソプロパノールおよびエタノールを含むアルコールであって、該イソプロパノールのエタノールに対する比率が、約1:100から約100:1までであるアルコールと、を含み、
前記消毒洗浄剤が乾燥した場合、該消毒洗浄剤が粘着性残留物を残さない消毒洗浄剤。 - イソプロパノールのエタノールに対する比率が、約1:3と約1:1との間にある請求項1に記載の方法。
- 前記アルコールが、前記洗浄剤の約90重量%を超えて含む請求項1に記載の方法。
- 前記洗浄剤が、5−クロロ−2−(2,4−ジクロロフェノキシ)フェノールをさらに含む請求項1に記載の方法。
- 前記5−クロロ−2−(2,4−ジクロロフェノキシ)フェノールが、洗浄剤の約0.01重量%から約10重量%までを構成する請求項4に記載の方法。
- 消毒洗浄剤において、
酢酸クロルヘキシジンと、
酢酸クロルヘキシジンを溶解可能な溶媒と、
吸収材とを含み、
前記吸収材は、前記洗浄剤で含浸され、
前記洗浄剤は、該洗浄剤が乾燥した場合、粘着性残留物を残さない消毒洗浄剤。 - 前記溶媒が、前記洗浄剤の90重量%を超えてを占めるアルコールを含む請求項6に記載の洗浄剤。
- 前記溶媒が、洗浄剤の約90.1重量%を超えて構成する水を含む請求項6に記載の洗浄剤。
- 前記洗浄剤の約0.01重量%から約10重量%までを構成する5−クロロ−2−(2,4−ジクロロフェノキシ)フェノールをさらに含む請求項6に記載の洗浄剤。
- 前記溶媒が、イソプロパノールおよびエタノールを含み、前記イソプロパノールとエタノールとの比率が、約1:10から約1:1までである請求項6に記載の洗浄剤。
- 前記吸収材が、カチオン性または非イオン性物質を含む請求項6に記載の洗浄剤。
- カチオン性または非イオン性物質が、ポリエステル、ポリプロピレン、カチオン性界面活性剤で被覆された綿、およびシリコーンから選択される請求項11に記載の洗浄剤。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/349,347 US7704935B1 (en) | 2009-01-06 | 2009-01-06 | Chlorhexidine acetate antiseptic cleaning agent |
US12/349,347 | 2009-01-06 | ||
PCT/US2009/069209 WO2010080652A1 (en) | 2009-01-06 | 2009-12-22 | Chlorhexidine acetate antiseptic cleaning agent |
Publications (3)
Publication Number | Publication Date |
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JP2012514641A true JP2012514641A (ja) | 2012-06-28 |
JP2012514641A5 JP2012514641A5 (ja) | 2013-02-07 |
JP5689817B2 JP5689817B2 (ja) | 2015-03-25 |
Family
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Family Applications (1)
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JP2011545368A Active JP5689817B2 (ja) | 2009-01-06 | 2009-12-22 | 酢酸クロルヘキシジン消毒洗浄剤 |
Country Status (7)
Country | Link |
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US (1) | US7704935B1 (ja) |
EP (1) | EP2376129A1 (ja) |
JP (1) | JP5689817B2 (ja) |
CN (2) | CN102316906A (ja) |
AU (1) | AU2009335672B2 (ja) |
BR (1) | BRPI0924047A2 (ja) |
WO (1) | WO2010080652A1 (ja) |
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- 2009-12-22 AU AU2009335672A patent/AU2009335672B2/en active Active
- 2009-12-22 CN CN200980156582XA patent/CN102316906A/zh active Pending
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EP2376129A1 (en) | 2011-10-19 |
AU2009335672A1 (en) | 2011-07-28 |
CN106106493A (zh) | 2016-11-16 |
WO2010080652A1 (en) | 2010-07-15 |
US7704935B1 (en) | 2010-04-27 |
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JP5689817B2 (ja) | 2015-03-25 |
AU2009335672B2 (en) | 2015-05-07 |
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