JP5539959B2 - 静電紡糸デキストラン繊維を有する薬剤及び包帯 - Google Patents
静電紡糸デキストラン繊維を有する薬剤及び包帯 Download PDFInfo
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Description
110 紡糸デキストラン繊維
120 支持材
130 第1端
140 第2端
200 管
210 開口
220 開口
300 プランジャ
400 殺菌パッケージ
Claims (14)
- 静電紡糸デキストラン繊維を有する第1の静電紡糸デキストラン繊維マットと、これに隣接する静電紡糸デキストラン繊維を有する第2の静電紡糸デキストラン繊維マットと、及び
トロンビン及びフィブリノーゲンとを有する薬剤であって、
上記静電紡糸デキストラン繊維が出血個所の液体内に直ちに溶け、上記トロンビン及びフィブリノーゲンが上記液体内に放出され、上記出血個所を止血する薬剤。
- 上記静電紡糸デキストラン繊維が0.75ミクロンから1.00ミクロンの直径のものである請求項1記載の薬剤。
- 上記出血個所が体の一部である請求項1記載の薬剤。
- 上記液体が体液である請求項3記載の薬剤。
- 上記薬剤が生物学的活性剤である請求項1記載の薬剤。
- 第1面を有する第1の静電紡糸デキストラン繊維マットと、第1面を有する第2の静電紡糸デキストラン繊維マットと、トロンビン及びフィブリノーゲンとを有し、上記静電紡糸デキストラン繊維が液体に接して溶ける0.75ミクロンから1.25ミクロンの直径のものであり、上記第2の静電紡糸デキストラン繊維マットが上記第1の静電紡糸繊維マットの上記第1面上に配置されている包帯。
- 上記トロンビン及びフィブリノーゲンがサーモントロンビン及びサーモンフィブリノーゲンである請求項6記載の包帯。
- 上記トロンビン及びフィブリノーゲンが微粒子状である請求項6記載の包帯。
- 上記トロンビン及びフィブリノーゲンが静電紡糸滴内に存在する請求項6記載の包帯。
- 1つまたは1つ以上の生物学的活性剤を含む請求項6記載の包帯。
- 更に支持材料を有する請求項6記載の包帯。
- 上記支持材料が、ガーゼ、圧縮静電紡糸デキストラン、ポリグリコール酸ポリマ類、ポリアクリル酸ポリマ類、カプロラクタンポリマ類及び帯電ナイロンから成る群から選んだ材料を含む請求項11記載の包帯。
- 0.75ミクロンから1.25ミクロンの直径の静電紡糸デキストラン繊維を有する第1の静電紡糸デキストラン繊維マットと、0.75ミクロンから1.25ミクロンの直径の第2の静電紡糸デキストラン繊維マット、トロンビン及びフィブリノーゲンとを有し、上記第2の静電紡糸デキストラン繊維マットが、上記第1の静電紡糸デキストラン繊維マットの上に配置され、
傷内の血液内に上記静電紡糸デキストラン繊維が直ちに溶け、上記トロンビンとフィブリノーゲンの少なくとも1つが上記傷内の血液内に供給され、上記傷の止血がなされる、傷の止血用包帯。 - 上記傷が貫通傷であり、この貫通傷の空洞内に挿入される請求項13記載の止血用包帯。
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