JP5345275B2 - 超音波データと事前取得イメージの重ね合わせ - Google Patents
超音波データと事前取得イメージの重ね合わせ Download PDFInfo
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Description
本発明は、医療用イメージングシステムに関し、詳細には、複数の超音波イメージから3次元臓器モデルを作成するための方法およびシステムに関する。
心内膜(すなわち、心臓の内面)の3次元(3D)マッピングの方法は当分野で周知である。心臓の地図を作成する方法が、例えば、言及することを以ってその開示内容を本明細書の一部とする米国特許第5,738,096号に開示されている。この方法では、侵襲性プローブが心臓の壁部の多数の位置に接触させられる。侵襲性プローブのポジションを各位置について決定し、これらのポジションを組み合わせて心臓の少なくとも一部分の構造地図を作成する。
心臓の3次元イメージングは、カテーテルを用いた診断および治療に有用である。リアルタイムイメージングにより、医師の技能が向上し、経験の浅い医師でも、複雑な外科処置を容易に行うことができる。3Dイメージングはまた、ある種の外科処置にかかる時間の短縮に役立つ。加えて、3D超音波イメージを、複雑な処置およびカテーテルの操作の計画に用いることができる。
本発明は、添付の図面を参照しながら以下の実施態様の詳細な説明を読めばより良く理解できるであろう。
1.リアルタイムまたは準リアルタイム(NRT)の2D超音波イメージの表示(図4および図6を参照)
2.2D超音波イメージに基づいた患者の体内の標的構造の3Dモデルの再構築(図4‐図10を参照)
3.再構築された3Dモデルに対する電気生理学的情報地図または電気解剖学的地図などのパラメットリック地図の重ね合わせ、オーバーレイ、および表示(図8を参照)
4.再構築された3Dモデルに対する外部システムから取得した3Dイメージの重ね合わせ、オーバーレイ、および表示
5.外部システムから取得した3Dイメージに対する2D超音波イメージの重ね合わせおよび表示(図11を参照)
図3は、本発明の一実施形態に従った心臓のマッピングおよびイメージングの方法を模式的に例示するフローチャートである。原理上は、開示する方法は、カテーテルの異なるポジションで取得した複数の2D超音波イメージを標的構造の1つの3Dモデルに組み合わせる。本特許出願および特許請求の範囲の文脈において、「標的構造」または「標的」は、心室全体または一部、または特定の壁、表面、血管、または他の解剖学的構造を指す。ここに記載する実施形態は特に心臓またはその周りの構造を指すが、本発明の原理は、必要な変更を加えて、骨、筋肉、他の臓器、および解剖学的構造のイメージングに同様に適用することができる。
図4‐図8は、本発明の実施形態に従った、上記した3Dイメージング法を視覚的に明示するイメージである。これらの図面は、発明者によって実現された心臓イメージングシステムによって生成された超音波イメージから作成した。これらのイメージは、図2に示されているカテーテルに類似したカテーテルを用いて豚の心臓をイメージングした実際に生きている動物の実験の際に取得した。
(1)患者の体内の標的をイメージングするためのシステムにおいて、
事前取得イメージと、
ポジションセンサおよび超音波イメージングセンサを含むカテーテルであって、前記ポジションセンサが、前記患者の体内の前記カテーテルの一部のポジション情報を示す電気信号を送信し、前記超音波イメージングセンサが、前記患者の体内の前記標的に超音波エネルギーを送り、前記患者の体内の前記標的から反射された超音波エコーを受け取り、かつ前記患者の体内の前記標的から反射された前記超音波エコーに関連した信号を送信する、前記カテーテルと、
前記ポジションセンサによって送信される前記電気信号に基づいて、前記カテーテルの前記一部のポジション情報を決定するために前記カテーテルに機能的に接続された位置決定プロセッサと、
前記カテーテルおよび前記位置決定プロセッサに機能的に接続されたイメージプロセッサであって、前記超音波センサによって送信される前記信号に基づいて前記標的の超音波イメージを生成し、前記標的の前記超音波イメージの全てのピクセルについてのポジション情報を決定し、前記超音波イメージに前記事前取得イメージを重ね合わせる、前記イメージプロセッサと、
前記重ね合わされた事前取得イメージと前記超音波イメージを表示するためのディスプレイと、を含む、システム。
(2)実施態様(1)に記載のシステムにおいて、
前記超音波イメージが、少なくとも1つの2次元超音波イメージである、システム。
(3)実施態様(2)に記載のシステムにおいて、
前記イメージプロセッサが、前記少なくとも1つの2次元超音波イメージから3次元モデルを再構築し、前記事前取得イメージが、前記3次元モデルに重ね合わされる、システム。
(4)実施態様(2)に記載のシステムにおいて、
前記ポジションセンサが、前記ポジション情報として位置および向きの座標を決定するために用いられる、システム。
(5)実施態様(4)に記載のシステムにおいて、
前記ポジションセンサが電磁場に応答する、システム。
前記電磁場が前記カテーテルの動作容積部を画定する、システム。
(7)実施態様(6)に記載のシステムにおいて、
前記超音波イメージングセンサが、超音波トランスデューサのアレイである、システム。
(8)実施態様(7)に記載のシステムにおいて、
前記超音波トランスデューサのアレイがフェーズドアレイである、システム。
(9)実施態様(8)に記載のシステムにおいて、
前記事前取得イメージがMRIイメージである、システム。
(10)実施態様(8)に記載のシステムにおいて、
前記事前取得イメージがCTイメージである、システム。
前記事前取得イメージがX線イメージである、システム。
(12)患者の体内の標的をイメージするための方法において、
前記標的の事前取得イメージを用意するステップと、
ポジションセンサおよび超音波イメージングセンサを含むカテーテルを前記患者の体内に配置し、前記ポジションセンサを用いて前記患者の体内の前記カテーテルの一部のポジション情報を決定するステップと、
前記超音波イメージングセンサを用いて前記標的の超音波イメージを生成するステップと、
前記標的の前記超音波イメージの全てのピクセルについてのポジション情報を決定し、前記事前取得イメージを前記超音波イメージに重ね合わせるステップと、
前記重ね合わされた事前取得イメージと超音波イメージを表示するステップと、を含む、方法。
(13)実施態様(12)に記載の方法において、
点を用いて前記事前取得イメージと前記超音波イメージを重ね合わせるステップをさらに含む、方法。
(14)実施態様(12)に記載の方法において、
輪郭を用いて前記事前取得イメージと前記超音波イメージを重ね合わせるステップをさらに含む、方法。
(15)実施態様(12)に記載の方法において、
表面を用いて前記事前取得イメージと前記超音波イメージを重ね合わせるステップをさらに含む、方法。
容積部を用いて前記事前取得イメージと前記超音波イメージを重ね合わせるステップをさらに含む、方法。
Claims (10)
- 患者の体内の標的をイメージングするためのシステムにおいて、
事前取得イメージと、
ポジションセンサおよび超音波イメージングセンサを含むカテーテルであって、前記ポジションセンサが、前記患者の体内の前記カテーテルの一部のポジション情報を示す電気信号を送信し、前記超音波イメージングセンサが、前記患者の体内の前記標的に超音波エネルギーを送り、前記患者の体内の前記標的から反射された超音波エコーを受け取り、かつ前記患者の体内の前記標的から反射された前記超音波エコーに関連した信号を送信する、前記カテーテルと、
前記ポジションセンサによって送信される前記電気信号に基づいて、前記カテーテルの前記一部のポジション情報を決定するために前記カテーテルに機能的に接続された位置決定プロセッサと、
前記カテーテルおよび前記位置決定プロセッサに機能的に接続されたイメージプロセッサであって、
前記超音波センサによって送信される前記信号に基づいて前記標的の少なくとも2つの2次元超音波イメージを生成し、
前記生成された超音波イメージ上にタグ付けされた、1またはそれ以上の目的の輪郭に対応する、1またはそれ以上のピクセルについてのポジション情報を決定し、前記1またはそれ以上の目的の輪郭は前記標的の1またはそれ以上のフィーチャーを特定し、
前記少なくとも2つの2次元超音波イメージから3次元モデルを再構築し、
前記3次元モデルに前記事前取得イメージを重ね合わせるように構成されている、前記イメージプロセッサと、
前記重ね合わされた事前取得イメージを前記3次元モデルと一緒に表示するためのディスプレイと、
を含む、システム。 - 請求項1に記載のシステムにおいて、
前記ポジションセンサが、前記ポジション情報として位置および向きの座標を決定するために用いられる、システム。 - 請求項2に記載のシステムにおいて、
前記ポジションセンサが電磁場に応答する、システム。 - 請求項3に記載のシステムにおいて、
前記電磁場が前記カテーテルの動作容積部を画定する、システム。 - 請求項4に記載のシステムにおいて、
前記超音波イメージングセンサが、超音波トランスデューサのアレイである、システム。 - 請求項5に記載のシステムにおいて、
前記超音波トランスデューサのアレイがフェーズドアレイである、システム。 - 請求項6に記載のシステムにおいて、
前記事前取得イメージがMRIイメージである、システム。 - 請求項6に記載のシステムにおいて、
前記事前取得イメージがCTイメージである、システム。 - 請求項6に記載のシステムにおいて、
前記事前取得イメージがX線イメージである、システム。 - 請求項1に記載のシステムにおいて、前記イメージプロセッサが、前記生成された超音波イメージ上にタグ付けされた前記1またはそれ以上の目的の輪郭に基づいて、タグ付けされていない超音波イメージにタグ付けする、システム。
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2005
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2019070754A1 (en) * | 2017-10-05 | 2019-04-11 | EchoNous, Inc. | SYSTEM AND METHOD FOR ULTRASONIC FUSION WITH ADDITIONAL SIGNALS |
US10507009B2 (en) | 2017-10-05 | 2019-12-17 | EchoNous, Inc. | System and method for fusing ultrasound with additional signals |
Also Published As
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EP1720038A3 (en) | 2008-02-27 |
CN1853574B (zh) | 2010-12-22 |
EP3199977B1 (en) | 2019-12-25 |
MXPA06004654A (es) | 2007-02-08 |
IL175187A0 (en) | 2006-09-05 |
KR20060112239A (ko) | 2006-10-31 |
BRPI0601508A (pt) | 2006-12-26 |
CA2544020A1 (en) | 2006-10-26 |
EP1720038A2 (en) | 2006-11-08 |
US20060253031A1 (en) | 2006-11-09 |
JP2006305357A (ja) | 2006-11-09 |
EP3199977A1 (en) | 2017-08-02 |
CN1853574A (zh) | 2006-11-01 |
EP1720038B1 (en) | 2017-03-15 |
IL175187A (en) | 2011-04-28 |
US10143398B2 (en) | 2018-12-04 |
AU2006201451B2 (en) | 2012-09-20 |
AU2006201451A1 (en) | 2006-11-09 |
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