JP4970938B2 - エアゾール化された薬剤を生成するためのネブライザ - Google Patents
エアゾール化された薬剤を生成するためのネブライザ Download PDFInfo
- Publication number
- JP4970938B2 JP4970938B2 JP2006521094A JP2006521094A JP4970938B2 JP 4970938 B2 JP4970938 B2 JP 4970938B2 JP 2006521094 A JP2006521094 A JP 2006521094A JP 2006521094 A JP2006521094 A JP 2006521094A JP 4970938 B2 JP4970938 B2 JP 4970938B2
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- Prior art keywords
- nebulizer
- aerosol generator
- aerosol
- drug
- protector
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- 239000006199 nebulizer Substances 0.000 title claims description 99
- 239000003814 drug Substances 0.000 title claims description 68
- 229940079593 drug Drugs 0.000 title claims description 58
- 239000000443 aerosol Substances 0.000 claims description 97
- 239000007788 liquid Substances 0.000 claims description 16
- 230000001012 protector Effects 0.000 claims description 13
- 210000002345 respiratory system Anatomy 0.000 claims description 8
- 230000001939 inductive effect Effects 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 230000029058 respiratory gaseous exchange Effects 0.000 claims description 6
- 230000005484 gravity Effects 0.000 claims description 5
- 230000008859 change Effects 0.000 claims description 4
- 230000006698 induction Effects 0.000 claims 1
- 230000000241 respiratory effect Effects 0.000 claims 1
- 239000007789 gas Substances 0.000 description 15
- 238000000034 method Methods 0.000 description 5
- 101150038956 cup-4 gene Proteins 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000003990 capacitor Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000003032 molecular docking Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229920002492 poly(sulfone) Polymers 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 238000010408 sweeping Methods 0.000 description 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 201000003883 Cystic fibrosis Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000010292 electrical insulation Methods 0.000 description 1
- 239000012777 electrically insulating material Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 230000003434 inspiratory effect Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8237—Charging means
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medicinal Preparation (AREA)
- Nozzles (AREA)
- Special Spraying Apparatus (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Description
Pout=1W
fout=128kHz
Vout=54Vms
ACリップルは無視できると仮定されるので、Cdcは無視される。
Q1はオンになり、Q2はオフになる。
矢印の方向に正電流。
モードの式は以下の式を使用して解く。
Vbus=VLres+VCp(t)
Q1はオフになり、Q2はオフである。
Q2の逆並列ダイオードを通じた電流フリーホイール。
モードの式。
VLres(t)+VCp(t)+VDQ2=0
Q1はオフになり、Q2はオンになる。
矢印の方向に正電流。
モードの式。
VLres(t)+Vcp(t)=0
Q2はオフになり、Q1はオフである。
Q1の逆並列ダイオードを通じた電流フリーホイール。
モードの式。
VCp(t)+VLres(t)−VDQ1−VCbus=0
Claims (22)
- 液体薬剤を送達するネブライザであって、
前記薬剤のためのリザーバを有するハウジングと、
振動可能な部材であって該部材の第1の表面と第2の表面との間に延びる複数の開口を有する振動可能な部材を備えるエアゾール発生器であって、前記リザーバから前記薬剤の供給を受けることができ、前記薬剤の少なくとも一部をエアゾール化するエアゾール発生器と、
気体がネブライザに流入して前記エアゾールとの混合物を形成できるようにする気体通気入口と、
通路であって、該通路を通じて、前記エアゾールと前記気体との前記混合物が前記ネブライザの出口ポートに送達される通路と、
前記エアゾール発生器のための駆動回路と、を備え、
前記駆動回路は、前記振動可能な部材が振動するように前記振動可能な部材の振動周波数を第1の周波数と第2の周波数との間で変化させるよう構成される、
ネブライザ。 - 前記薬剤が、重力流れによって前記リザーバから前記エアゾール発生器に供給される、請求項1に記載のネブライザ。
- 前記気体通気入口が前記エアゾール発生器のすぐ近くに配置される、請求項1に記載のネブライザ。
- 前記ハウジングが、前記気体と前記エアゾールとの前記混合物を前記出口ポートに指向させるバッフルを有する、請求項1に記載のネブライザ。
- 前記バッフルが、エアゾールが前記出口ポートを通じて流れるように方向付けられた傾斜表面を備える、請求項4に記載のネブライザ。
- 前記ネブライザがエアゾール液滴トラップを備える、請求項1に記載のネブライザ。
- 前記液滴トラップが前記出口ポートに隣接する、請求項6に記載のネブライザ。
- 前記エアゾール発生器が、前記エアゾール発生器を物理的損傷から保護するプロテクタを有し、前記プロテクタが
(a)前記エアゾール発生器の上方の上方プロテクタ、及び
(b)前記エアゾール発生器の下方の下方プロテクタ、
のうち少なくとも一方を備える、
請求項1に記載のネブライザ。 - 前記上方プロテクタ又は下方プロテクタがメッシュを備える、請求項8に記載のネブライザ。
- 前記下方プロテクタが前記ネブライザの前記ハウジングと一体である、請求項8に記載のネブライザ。
- 前記ネブライザが、前記出口ポートを呼吸系に接続する呼吸コネクタを備える、請求項1に記載のネブライザ。
- 前記呼吸コネクタが、マウスピース、フェースマスク、及びノーズピースからなるグループから選択される、請求項11に記載のネブライザ。
- 前記ネブライザが、前記エアゾール発生器を保持するエアゾール発生器ハウジングを備え、前記エアゾール発生器ハウジングが前記リザーバに固定される、請求項1に記載のネブライザ。
- 70重量%又はそれ以上の液滴の寸法が1から6マイクロメートルの範囲にあるように前記薬剤の液滴を放出することにより前記薬剤がエアゾール化されるように、前記振動可能な部材の前記開口が寸法設定されている、請求項1に記載のネブライザ。
- 前記駆動回路がプッシュプル共振電力回路を備える、請求項1に記載のネブライザ。
- 前記振動可能な部材が圧電素子を備え、前記プッシュプル共振電力回路が誘導素子を備える、請求項15に記載のネブライザ。
- 前記プッシュプル共振電力回路が誘導素子を備える、請求項15に記載のネブライザ。
- 前記プッシュプル共振電力回路が、オンオフ構成でもって作動される一対のMOSFETスイッチを備える、請求項15に記載のネブライザ。
- 前記エアゾール発生器に結合された電源インレットを含むエアゾール発生器組体を備え、前記組体の少なくとも一部が電気的に絶縁された弾性ケーシングに収容される、請求項1に記載のネブライザ。
- 前記駆動回路は、前記エアゾール発生器に結合され、壁コンセントに直接差し込まれて周波数が50Hzから60Hzであり90Vから250Vの範囲の交流電圧の入力を受け取るのに適しており、50Khzから300kHzの動作周波数範囲の交流電圧出力を発生する、請求項1に記載のネブライザ。
- 前記駆動回路は、前記エアゾール発生器に結合され、バッテリと共に使用するのに適しており、1.5から12ボルトの範囲の電圧の入力を受け取り、50kHzから300kHzの動作周波数範囲の交流電圧出力を発生する、請求項1に記載のネブライザ。
- 前記駆動回路が、前記動作周波数においてインピーダンスが前記ネブライザの回路と同じである誘導素子を備える、請求項20又は21に記載のネブライザ。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48871803P | 2003-07-18 | 2003-07-18 | |
US60/488,718 | 2003-07-18 | ||
US10/833,932 US8616195B2 (en) | 2003-07-18 | 2004-04-27 | Nebuliser for the production of aerosolized medication |
US10/833,932 | 2004-04-27 | ||
PCT/US2004/021628 WO2005009323A2 (en) | 2003-07-18 | 2004-07-06 | A nebuliser for the production of aerosolized medication |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2006528025A JP2006528025A (ja) | 2006-12-14 |
JP2006528025A5 JP2006528025A5 (ja) | 2011-12-08 |
JP4970938B2 true JP4970938B2 (ja) | 2012-07-11 |
Family
ID=34068458
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006521094A Expired - Lifetime JP4970938B2 (ja) | 2003-07-18 | 2004-07-06 | エアゾール化された薬剤を生成するためのネブライザ |
Country Status (7)
Country | Link |
---|---|
US (1) | US8616195B2 (ja) |
EP (2) | EP1646276B1 (ja) |
JP (1) | JP4970938B2 (ja) |
AU (1) | AU2004258880B2 (ja) |
CA (1) | CA2532978C (ja) |
NO (1) | NO336224B1 (ja) |
WO (1) | WO2005009323A2 (ja) |
Families Citing this family (114)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6540154B1 (en) * | 1991-04-24 | 2003-04-01 | Aerogen, Inc. | Systems and methods for controlling fluid feed to an aerosol generator |
US5758637A (en) | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US6235177B1 (en) | 1999-09-09 | 2001-05-22 | Aerogen, Inc. | Method for the construction of an aperture plate for dispensing liquid droplets |
US6948491B2 (en) * | 2001-03-20 | 2005-09-27 | Aerogen, Inc. | Convertible fluid feed system with comformable reservoir and methods |
MXPA02010884A (es) * | 2000-05-05 | 2003-03-27 | Aerogen Ireland Ltd | Aparato y metodo para el suministro de medicamentos al sistema respiratorio. |
US8336545B2 (en) * | 2000-05-05 | 2012-12-25 | Novartis Pharma Ag | Methods and systems for operating an aerosol generator |
US7971588B2 (en) * | 2000-05-05 | 2011-07-05 | Novartis Ag | Methods and systems for operating an aerosol generator |
US7600511B2 (en) * | 2001-11-01 | 2009-10-13 | Novartis Pharma Ag | Apparatus and methods for delivery of medicament to a respiratory system |
US6968840B2 (en) | 2000-05-05 | 2005-11-29 | Aerogen, Inc. | Methods and systems for operating an aerosol generator |
WO2002074372A2 (en) | 2001-03-15 | 2002-09-26 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nebulizer having cooling chamber |
US6732944B2 (en) * | 2001-05-02 | 2004-05-11 | Aerogen, Inc. | Base isolated nebulizing device and methods |
US7677467B2 (en) * | 2002-01-07 | 2010-03-16 | Novartis Pharma Ag | Methods and devices for aerosolizing medicament |
CA2472644C (en) | 2002-01-07 | 2013-11-05 | Aerogen, Inc. | Devices and methods for nebulizing fluids for inhalation |
ES2572770T3 (es) * | 2002-05-20 | 2016-06-02 | Novartis Ag | Aparato para proporcionar pulverización para tratamiento médico y métodos |
US20070044792A1 (en) * | 2005-08-30 | 2007-03-01 | Aerogen, Inc. | Aerosol generators with enhanced corrosion resistance |
MXPA06011426A (es) * | 2004-04-02 | 2007-04-20 | Gov Health & Human Serv | Sistemas y metodos de suministro en aerosol. |
US7290541B2 (en) * | 2004-04-20 | 2007-11-06 | Aerogen, Inc. | Aerosol delivery apparatus and method for pressure-assisted breathing systems |
BRPI0509991A (pt) * | 2004-04-20 | 2007-10-16 | Aerogen Inc | aparelho de fornecimento em aerossol, métodos e composições para sistemas de respiração auxiliados por pressão |
US7946291B2 (en) | 2004-04-20 | 2011-05-24 | Novartis Ag | Ventilation systems and methods employing aerosol generators |
US7267121B2 (en) * | 2004-04-20 | 2007-09-11 | Aerogen, Inc. | Aerosol delivery apparatus and method for pressure-assisted breathing systems |
JP2007537833A (ja) * | 2004-05-20 | 2007-12-27 | ディスカバリー ラボラトリーズ,インコーポレイテッド | 非侵襲的な肺吸入のための方法、システム、及び装置 |
US7631643B2 (en) * | 2005-03-09 | 2009-12-15 | Ric Investments, Llc | Nebulizing drug delivery device with interlock detection and temperature protection |
US8028697B2 (en) | 2005-04-28 | 2011-10-04 | Trudell Medical International | Ventilator circuit and method for the use thereof |
SG163503A1 (en) * | 2005-05-25 | 2010-08-30 | Aerogen Inc | Vibration systems and methods |
ES2379383T3 (es) * | 2005-06-02 | 2012-04-25 | Ads&B Investment Fund L.P. | Un dispositivo vibratorio para tratar síntomas de congestión nasal y de sinusitis |
PT1962805T (pt) | 2005-12-08 | 2016-10-05 | Insmed Inc | Composições de anti-infeciosos baseadas em lípidos para tratamento de infeções pulmonares |
US20090241948A1 (en) * | 2007-03-28 | 2009-10-01 | Dermot Joseph Clancy | Humidification in breathing circuits |
WO2008117264A1 (en) * | 2007-03-28 | 2008-10-02 | Stamford Devices Limited | Insufflation of body cavities |
US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
WO2009111612A1 (en) * | 2008-03-07 | 2009-09-11 | Novartis Ag | Aerosolization device |
RU2463084C2 (ru) | 2008-03-17 | 2012-10-10 | Дискавери Лабораториз, Инк. | Адаптер дыхательного контура и система проксимальной доставки аэрозоля |
EP2349416B1 (en) * | 2008-09-26 | 2015-06-17 | Stamford Devices Limited | A nebuliser system |
EP2337600B1 (en) | 2008-09-26 | 2019-09-18 | Stamford Devices Limited | Supplemental oxygen delivery system |
JP2010099169A (ja) * | 2008-10-22 | 2010-05-06 | Koshin Kogyo:Kk | ネブライザ |
US8596265B2 (en) | 2008-10-22 | 2013-12-03 | Trudell Medical International | Modular aerosol delivery system |
GB0910537D0 (en) * | 2009-06-18 | 2009-07-29 | Ivax Pharmaceuticals Ireland | Inhaler |
CA2768379C (en) * | 2009-07-17 | 2017-10-10 | David Mark Blakey | Negatively biased sealed nebulizers systems and methods |
US9440020B2 (en) * | 2009-12-08 | 2016-09-13 | Medinvent, Llc | Nasal irrigator |
US8925544B2 (en) | 2009-12-08 | 2015-01-06 | Medinvent, Llc | Portable nebulizer device |
US20130269684A1 (en) | 2012-04-16 | 2013-10-17 | Dance Pharmaceuticals, Inc. | Methods and systems for supplying aerosolization devices with liquid medicaments |
US9180261B2 (en) | 2010-01-12 | 2015-11-10 | Dance Biopharm Inc. | Preservative free insulin formulations and systems and methods for aerosolizing |
JP5494186B2 (ja) * | 2010-04-28 | 2014-05-14 | オムロンヘルスケア株式会社 | ネブライザキットおよびネブライザ |
ES2654582T3 (es) * | 2010-05-13 | 2018-02-14 | Nortev Limited | Conjunto generador de aerosol |
US9402947B2 (en) | 2010-07-01 | 2016-08-02 | Medinvent, Llc | Portable fluid delivery system for the nasal and paranasal sinus cavities |
US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
US20170368273A1 (en) * | 2010-08-23 | 2017-12-28 | Darren Rubin | Systems and methods of aerosol delivery with airflow regulation |
US11247003B2 (en) * | 2010-08-23 | 2022-02-15 | Darren Rubin | Systems and methods of aerosol delivery with airflow regulation |
US10682331B2 (en) | 2012-02-24 | 2020-06-16 | Nasoneb, Inc. | Nasal drug delivery and method of making same |
JP3199314U (ja) | 2012-05-03 | 2015-08-20 | スタムフォード・ディバイセズ・リミテッド | 噴霧器 |
SI2852391T1 (sl) | 2012-05-21 | 2022-04-29 | Insmed Incorporated | Sistemi za obravnavo pljučnih infekcij |
RU2018135921A (ru) | 2012-11-29 | 2019-02-05 | Инсмед Инкорпорейтед | Стабилизированные составы ванкомицина |
US9038625B2 (en) * | 2013-02-05 | 2015-05-26 | Sheng-Pin Hu | Liquid spray device |
IL217513A0 (en) | 2013-09-04 | 2012-02-29 | Nektar Therapeutics | Negatively biased sealed nebulizers systems and methods |
US10092712B2 (en) * | 2013-11-04 | 2018-10-09 | Stamford Devices Limited | Aerosol delivery system |
JP1515878S (ja) * | 2014-03-12 | 2015-01-26 | ||
IL247954B2 (en) | 2014-04-03 | 2023-09-01 | Pari Pharma Gmbh | Immunoglobulin mobilisation |
DK3142643T3 (da) | 2014-05-15 | 2019-10-14 | Insmed Inc | Fremgangsmåder til behandling af ikke-tuberkuløse mykobakterielle lungeinfektioner |
AU2015274367B2 (en) | 2014-06-13 | 2020-11-26 | Beth Israel Deaconess Medical Center, Inc. | Products and methods to isolate mitochondria |
TWM487087U (zh) * | 2014-06-20 | 2014-10-01 | Taiwan Puritic Corp | 噴霧組件及其所形成之噴霧器 |
US9943873B1 (en) | 2014-06-20 | 2018-04-17 | Taiwan Puritic Corp. | Atomizing plug assembly and atomizer formed thereby |
US10471222B2 (en) * | 2014-07-01 | 2019-11-12 | Dance Biopharm Inc. | Aerosolization system with flow restrictor and feedback device |
US10857313B2 (en) * | 2014-07-01 | 2020-12-08 | Aerami Therapeutics, Inc. | Liquid nebulization systems and methods |
US11273271B2 (en) | 2014-07-01 | 2022-03-15 | Aerami Therapeutics, Inc. | Aerosolization system with flow restrictor and feedback device |
CN104069571B (zh) * | 2014-07-09 | 2017-04-12 | 捷锐企业(上海)有限公司 | 一种医用雾化室雾化给药装置 |
USD752207S1 (en) * | 2014-08-22 | 2016-03-22 | Microdose Therapeutx, Inc. | Dry powder nebulizer device |
USD752206S1 (en) * | 2014-08-22 | 2016-03-22 | Microdose Therapeutx, Inc. | Dry powder nebulizer device |
USD753285S1 (en) * | 2014-08-22 | 2016-04-05 | Microdose Therapeutx, Inc. | Dry powder nebulizer device |
USD752205S1 (en) * | 2014-08-22 | 2016-03-22 | Microdose Therapeutx, Inc. | Dry powder nebulizer device |
USD754329S1 (en) * | 2014-11-12 | 2016-04-19 | Medicus Engineering Aps | Mouthpiece for medical devices |
US10799652B2 (en) | 2015-01-08 | 2020-10-13 | Convexity Scientific Inc. | Nebulizer device |
US20160361506A1 (en) * | 2015-06-11 | 2016-12-15 | Delta Electronics, Inc. | Nebulization system, nebulizer and driving method thereof |
CN107921228B (zh) | 2015-06-23 | 2022-05-13 | 简易导气管公司 | 正压面罩及相关接合器、设备和方法 |
US11400248B2 (en) | 2015-06-23 | 2022-08-02 | Simplicity Airway, Inc. | Positive pressure ventilation elbow and related masks, systems, and methods |
CN105031778A (zh) * | 2015-09-16 | 2015-11-11 | 王天星 | 药物雾化器 |
US20180369508A1 (en) * | 2015-12-28 | 2018-12-27 | Koninklijke Philips N.V. | Air-flow in a nebulizer head |
TWD178053S (zh) * | 2016-01-26 | 2016-09-01 | 微邦科技股份有限公司 | 噴霧器 |
WO2017175218A2 (en) * | 2016-04-04 | 2017-10-12 | Nexvap Sa | A mobile inhaler and a container for using therewith |
US11285285B2 (en) | 2016-05-03 | 2022-03-29 | Pneuma Respiratory, Inc. | Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment |
GB201611639D0 (en) | 2016-07-04 | 2016-08-17 | Ockham Biotech Ltd | Delivery device and formulation |
EP3984579A1 (en) | 2016-07-08 | 2022-04-20 | Trudell Medical International | Smart oscillating positive expiratory pressure device |
WO2018011374A1 (en) * | 2016-07-15 | 2018-01-18 | Koninklijke Philips N.V. | Aerosolizaton device and an aerosol drug delivery device |
EP3272426B1 (en) * | 2016-07-19 | 2020-09-30 | Microbase Technology Corp. | Nebulization generating apparatus |
CN107661820B (zh) * | 2016-07-27 | 2020-01-07 | 和淞科技股份有限公司 | 喷雾装置 |
TWI664024B (zh) * | 2016-07-27 | 2019-07-01 | 和淞科技股份有限公司 | 噴霧裝置 |
JP6801335B2 (ja) * | 2016-09-27 | 2020-12-16 | オムロンヘルスケア株式会社 | 超音波振動子駆動装置およびメッシュ式ネブライザ |
CN107961939B (zh) * | 2016-10-20 | 2023-08-01 | 心诚镁行动医电股份有限公司 | 液体雾化电路及其装置 |
DE202017007545U1 (de) | 2016-12-09 | 2022-09-01 | Trudell Medical International | Intelligenter Vernebler |
CA3064005C (en) | 2017-05-19 | 2023-03-07 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
JP7227163B2 (ja) | 2017-06-10 | 2023-02-21 | アイノビア,インコーポレイティド | 流体を取扱い、目に流体を送出するための方法および装置 |
US20190054260A1 (en) * | 2017-08-17 | 2019-02-21 | Monzano Group LLC | Nebulizer devices and methods |
EP3691728B1 (en) | 2017-10-04 | 2024-05-22 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device |
WO2019079461A1 (en) | 2017-10-17 | 2019-04-25 | Pneuma Respiratory, Inc. | NASAL MEDICATION DELIVERY APPARATUS AND METHODS OF USE |
CN107596514A (zh) * | 2017-10-23 | 2018-01-19 | 洪丽 | 一种用于小儿临床治疗用的雾化吸入治疗器 |
JP2021502178A (ja) | 2017-11-08 | 2021-01-28 | ニューマ・リスパイラトリー・インコーポレイテッド | 小容積アンプルを有して呼吸により電気的に作動するインライン液滴送達装置および使用方法 |
EP3735287A4 (en) | 2018-01-04 | 2021-09-15 | Trudell Medical International | INTELLIGENT POSITIVE OSCILLATING EXPIRATORY PRESSURE DEVICE |
CN110115790B (zh) * | 2018-02-07 | 2021-08-06 | 心诚镁行动医电股份有限公司 | 雾化器组件及其气流主要导引件 |
JP7460534B2 (ja) | 2018-03-30 | 2024-04-02 | インスメッド インコーポレイテッド | リポソーム医薬品の連続製造方法 |
CN209060228U (zh) * | 2018-04-17 | 2019-07-05 | 华健 | 一种可调档位控制雾化量的便携式雾化器 |
CN109999282A (zh) * | 2018-04-20 | 2019-07-12 | 广东东阳光药业有限公司 | 一种雾化装置及快速雾化方法 |
US11690963B2 (en) | 2018-08-22 | 2023-07-04 | Qnovia, Inc. | Electronic device for producing an aerosol for inhalation by a person |
US11517685B2 (en) | 2019-01-18 | 2022-12-06 | Qnovia, Inc. | Electronic device for producing an aerosol for inhalation by a person |
EP3863453A4 (en) | 2018-10-18 | 2022-11-23 | Qnovia, Inc. | ELECTRONIC DEVICE FOR PRODUCING AN AEROSOL INTENDED TO BE INHALED BY A PERSON |
USD895101S1 (en) * | 2019-03-25 | 2020-09-01 | Shenzhen Bgmmed Technology Co., Ltd. | Handheld nebulizer |
WO2020214644A1 (en) * | 2019-04-15 | 2020-10-22 | Children's Medical Center Corporation | Aerosolized compositions comprising mitochondria and methods of use thereof |
USD893703S1 (en) * | 2019-05-07 | 2020-08-18 | Healthy Humming, LLC | Therapeutic device |
US11813397B2 (en) | 2019-06-11 | 2023-11-14 | Justin Rowley | Nebulizer with flutter valve |
CA3146251A1 (en) * | 2019-08-02 | 2021-02-11 | Stamford Devices Limited | Buccal administration of aerosol |
EP4021542A4 (en) | 2019-08-27 | 2023-09-06 | Trudell Medical International | INTELLIGENT OSCILLATING POSITIVE EXPIRATORY PRESSURE DEVICE |
US20210113783A1 (en) | 2019-10-20 | 2021-04-22 | Respira Technologies, Inc. | Electronic devices and liquids for aerosolizing and inhaling therewith |
CN110743067A (zh) * | 2019-10-22 | 2020-02-04 | 武汉光燚激光科技有限公司 | 雾化美容仪器 |
TWI747773B (zh) * | 2021-03-25 | 2021-11-21 | 心誠鎂行動醫電股份有限公司 | 給藥容器以及霧化裝置 |
EP4094793A1 (de) * | 2021-05-28 | 2022-11-30 | Löwenstein Medical Technology S.A. | Vorrichtung zur erzeugung von aeorosolen |
JP2024525200A (ja) | 2021-06-22 | 2024-07-10 | ニューマ・リスパイラトリー・インコーポレイテッド | プッシュ排出を用いる液滴送達デバイス |
US20230337735A1 (en) | 2022-04-22 | 2023-10-26 | Qnovia, Inc. | Electronic devices for aerosolizing and inhaling liquid |
Family Cites Families (443)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2735427A (en) | 1956-02-21 | Hypodermic syringe | ||
US2735007A (en) * | 1956-02-14 | Time-base generator | ||
US550315A (en) | 1895-11-26 | Frank napoleon allen | ||
US809159A (en) | 1905-09-30 | 1906-01-02 | Richard M Willis | Dispensing bottle or jar. |
US1680616A (en) | 1922-06-06 | 1928-08-14 | Horst Friedrich Wilhelm | Sealed package |
US2022520A (en) | 1934-07-07 | 1935-11-26 | Parsons Ammonia Company Inc | Bottle |
US2101304A (en) | 1936-06-05 | 1937-12-07 | Sheaffer W A Pen Co | Fountain pen |
US2187528A (en) | 1937-06-07 | 1940-01-16 | Russell T Wing | Fountain pen |
US2158615A (en) | 1937-07-26 | 1939-05-16 | Sheaffer W A Pen Co | Fountain pen |
US2266706A (en) | 1938-08-06 | 1941-12-16 | Stanley L Fox | Nasal atomizing inhaler and dropper |
NL62585C (ja) | 1939-01-06 | |||
US2292381A (en) | 1940-12-24 | 1942-08-11 | Esterbrook Steel Pen Mfg Co | Fountain pen feed |
US2283333A (en) | 1941-05-22 | 1942-05-19 | Sheaffer W A Pen Co | Fountain pen |
US2383098A (en) | 1942-07-21 | 1945-08-21 | Jr Frank H Wheaton | Double-mouthed bottle |
US2375770A (en) | 1943-11-19 | 1945-05-15 | Arthur O Dahiberg | Fountain pen |
US2430023A (en) | 1944-01-27 | 1947-11-04 | Esterbrook Pen Co | Writing implement |
BE461043A (ja) | 1944-04-10 | |||
US2404063A (en) | 1944-04-27 | 1946-07-16 | Parker Pen Co | Fountain pen |
US2521657A (en) | 1944-07-07 | 1950-09-05 | Scripto Inc | Fountain pen |
US2512004A (en) | 1945-03-05 | 1950-06-20 | Russell T Wing | Fountain pen |
US2474996A (en) | 1945-10-12 | 1949-07-05 | Sheaffer W A Pen Co | Fountain pen |
NL68028C (ja) | 1946-06-08 | |||
US2622593A (en) * | 1950-12-12 | 1952-12-23 | Peirano Horacio | Atomizing apparatus |
US2705007A (en) | 1951-09-10 | 1955-03-29 | Louis P Gerber | Inhaler |
US2764979A (en) | 1953-04-09 | 1956-10-02 | Henderson Edward | Medicament dispensing unit |
US2764946A (en) | 1954-04-05 | 1956-10-02 | Scognamillo Frank | Rotary pump |
US2779623A (en) | 1954-09-10 | 1957-01-29 | Bernard J Eisenkraft | Electromechanical atomizer |
US2935970A (en) | 1955-03-23 | 1960-05-10 | Sapphire Products Inc | Fountain pen ink reservoir |
DE1103522B (de) | 1957-10-24 | 1961-03-30 | Transform Roentgen Matern Veb | Abatmungseinrichtung fuer mittels Ultraschall erzeugte Aerosole |
US3103310A (en) | 1961-11-09 | 1963-09-10 | Exxon Research Engineering Co | Sonic atomizer for liquids |
GB973458A (en) | 1962-10-16 | 1964-10-28 | Exxon Research Engineering Co | Improvements in or relating to methods and apparatus for atomising liquids |
FR1449600A (fr) | 1964-09-14 | 1966-05-06 | Fr Des Laboratoires Labaz Soc | Perfectionnements aux flacons en matière souple, notamment pour produits médicamenteux |
DE1461628A1 (de) | 1965-04-30 | 1969-03-27 | Montblanc Simplo Gmbh | Tintenleiter fuer Fuellfederhalter |
US3680954A (en) | 1965-04-30 | 1972-08-01 | Eastman Kodak Co | Electrography |
DE1575050A1 (de) | 1966-01-12 | 1972-04-13 | Misto Gen Equipment Co | Ultraschall-Nebelerzeugungsgeraet |
US3550864A (en) | 1967-12-11 | 1970-12-29 | Borg Warner | High efficiency flashing nozzle |
US3561444A (en) | 1968-05-22 | 1971-02-09 | Bio Logics Inc | Ultrasonic drug nebulizer |
US3515348A (en) | 1968-07-22 | 1970-06-02 | Lewbill Ind Inc | Mist-producing device |
US3558052A (en) | 1968-10-31 | 1971-01-26 | F I N D Inc | Method and apparatus for spraying electrostatic dry powder |
US3563415A (en) | 1969-06-04 | 1971-02-16 | Multi Drop Adapter Corp | Multidrop adapter |
US3719328A (en) | 1970-10-22 | 1973-03-06 | C Hindman | Adjustable spray head |
CA930005A (en) | 1971-06-15 | 1973-07-10 | Siemens Aktiengesellschaft | Piezoelectric vibrators |
DE2133377C3 (de) * | 1971-07-05 | 1981-06-25 | Paul Ritzau Pari-Werk, Gmbh & Co, 8130 Starnberg | Gerät zur Erzeugung von Feuchtigkeitsnebeln |
NO134730L (ja) | 1971-07-19 | 1900-01-01 | ||
US3838686A (en) | 1971-10-14 | 1974-10-01 | G Szekely | Aerosol apparatus for inhalation therapy |
US3983740A (en) | 1971-12-07 | 1976-10-05 | Societe Grenobloise D'etudes Et D'applications Hydrauliques (Sogreah) | Method and apparatus for forming a stream of identical drops at very high speed |
US3790079A (en) | 1972-06-05 | 1974-02-05 | Rnb Ass Inc | Method and apparatus for generating monodisperse aerosol |
US3778786A (en) | 1972-06-28 | 1973-12-11 | Nasa | Data storage, image tube type |
US3812854A (en) | 1972-10-20 | 1974-05-28 | A Michaels | Ultrasonic nebulizer |
US3842833A (en) | 1972-12-11 | 1974-10-22 | Ims Ltd | Neb-u-pack |
FR2224175B1 (ja) | 1973-04-04 | 1978-04-14 | Isf Spa | |
AT323114B (de) | 1973-05-07 | 1975-06-25 | Voest Ag | Verfahren zum prillen |
US3804329A (en) | 1973-07-27 | 1974-04-16 | J Martner | Ultrasonic generator and atomizer apparatus and method |
US3903884A (en) | 1973-08-15 | 1975-09-09 | Becton Dickinson Co | Manifold nebulizer system |
DE2361781A1 (de) | 1973-12-12 | 1975-06-19 | Philips Patentverwaltung | Schreibwerk zum schreiben mit fluessiger farbe |
US3865106A (en) | 1974-03-18 | 1975-02-11 | Bernard P Palush | Positive pressure breathing circuit |
US3951313A (en) | 1974-06-05 | 1976-04-20 | Becton, Dickinson And Company | Reservoir with prepacked diluent |
US3993223A (en) | 1974-07-25 | 1976-11-23 | American Home Products Corporation | Dispensing container |
US3908654A (en) | 1974-08-02 | 1975-09-30 | Rit Rech Ind Therapeut | Dispensing package for a dry biological and a liquid diluent |
DE2445791C2 (de) | 1974-09-25 | 1984-04-19 | Siemens AG, 1000 Berlin und 8000 München | Ultraschall-Flüssigkeitszerstäuber |
AR205589A1 (es) | 1974-10-09 | 1976-05-14 | Reckitt & Colmann Prod Ltd | Dispositivo introductor de una composicion acuosa en una cavidad corporal |
US3958249A (en) | 1974-12-18 | 1976-05-18 | International Business Machines Corporation | Ink jet drop generator |
US4059384A (en) | 1975-01-20 | 1977-11-22 | Misto2 Gen Equipment Co. | Two-step injection molding |
AT337345B (de) | 1975-02-05 | 1977-06-27 | Draegerwerk Ag | Gerat zur unterstutzung der atmung und/oder kunstlichen beatmung zur humanen verwendung |
US4005435A (en) | 1975-05-15 | 1977-01-25 | Burroughs Corporation | Liquid jet droplet generator |
AU67278S (en) | 1975-06-04 | 1975-11-12 | Warner Lambert Co | Bottle |
DE2537765B2 (de) | 1975-08-25 | 1981-04-09 | Siemens AG, 1000 Berlin und 8000 München | Medizinisches Inhalationsgerät zur Behandlung von Krankheiten der Atmungswege |
GB1571304A (en) | 1976-02-24 | 1980-07-16 | Lucas Industries Ltd | Drive circuit for a piezo electric crystal |
US4094317A (en) | 1976-06-11 | 1978-06-13 | Wasnich Richard D | Nebulization system |
US4121583A (en) | 1976-07-13 | 1978-10-24 | Wen Yuan Chen | Method and apparatus for alleviating asthma attacks |
US4076021A (en) | 1976-07-28 | 1978-02-28 | Thompson Harris A | Positive pressure respiratory apparatus |
US4083368A (en) | 1976-09-01 | 1978-04-11 | Freezer Winthrop J | Inhaler |
USD249958S (en) | 1977-01-10 | 1978-10-17 | Warner-Lambert Company | Dispensing container for pharmaceutical diluents |
US4106503A (en) | 1977-03-11 | 1978-08-15 | Richard R. Rosenthal | Metering system for stimulating bronchial spasm |
US4159803A (en) | 1977-03-31 | 1979-07-03 | MistO2 Gen Equipment Company | Chamber for ultrasonic aerosol generation |
US4113809A (en) | 1977-04-04 | 1978-09-12 | Champion Spark Plug Company | Hand held ultrasonic nebulizer |
US4101041A (en) | 1977-08-01 | 1978-07-18 | Becton, Dickinson And Company | Prefillable, hermetically sealed container adapted for use with a humidifier or nebulizer head |
US4268460A (en) | 1977-12-12 | 1981-05-19 | Warner-Lambert Company | Nebulizer |
USD259213S (en) | 1978-03-13 | 1981-05-12 | Automatic Liquid Packaging, Inc. | Vial suitable for pharmaceuticals |
DE2811248C3 (de) | 1978-03-15 | 1981-11-26 | Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart | Flüssigkeitszerstäuber |
US4298045A (en) | 1978-04-17 | 1981-11-03 | Automatic Liquid Packaging, Inc. | Dispensing container with plural removable closure means unitary therewith |
US4338576A (en) | 1978-07-26 | 1982-07-06 | Tdk Electronics Co., Ltd. | Ultrasonic atomizer unit utilizing shielded and grounded elements |
US4210155A (en) | 1978-08-03 | 1980-07-01 | Jerry Grimes | Inspirational inhalation spirometer apparatus |
DE2843756C3 (de) | 1978-10-06 | 1988-05-26 | Klarhorst, Günter, 4800 Bielefeld | Vorrichtung zum Erzeugen eines Aerosols |
US4240081A (en) | 1978-10-13 | 1980-12-16 | Dennison Manufacturing Company | Ink jet printing |
DE2849493C2 (de) | 1978-11-15 | 1982-01-14 | Carl Heyer Gmbh, Inhalationstechnik, 5427 Bad Ems | In der Hand zu haltender Aerosolspender |
DE2854841C2 (de) | 1978-12-19 | 1981-03-26 | Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart | Flüssigkeitszerstäuber, vorzugsweise Inhalationsgerät |
JPS5848225B2 (ja) | 1979-01-09 | 1983-10-27 | オムロン株式会社 | 超音波液体霧化装置の霧化量制御方式 |
DE2907348A1 (de) | 1979-02-24 | 1980-09-04 | Boehringer Sohn Ingelheim | Verbesserte inhalationsgeraete |
US4207990A (en) | 1979-05-03 | 1980-06-17 | Automatic Liquid Packaging, Inc. | Hermetically sealed container with plural access ports |
US4226236A (en) | 1979-05-07 | 1980-10-07 | Abbott Laboratories | Prefilled, vented two-compartment syringe |
US4248227A (en) | 1979-05-14 | 1981-02-03 | Bristol-Myers Company | Fluid unit dispensing device |
US4240417A (en) | 1979-06-13 | 1980-12-23 | Holever Bernard K | Tracheal tube adapter for ventilating apparatus |
DE7917568U1 (de) | 1979-06-19 | 1979-09-20 | Bosch-Siemens Hausgeraete Gmbh, 7000 Stuttgart | Inhalationsgeraet |
JPS5689569A (en) | 1979-12-19 | 1981-07-20 | Canon Inc | Ink jet recording head |
US4368850A (en) | 1980-01-17 | 1983-01-18 | George Szekely | Dry aerosol generator |
DE3010178C2 (de) | 1980-03-17 | 1985-10-03 | Kraftwerk Union AG, 4330 Mülheim | Mit einem Schnellschlußventil ausgerüstete Schlitzdüse zur Herbeiführung impulsartiger Gasströmungen |
NL189237C (nl) | 1980-04-12 | 1993-02-16 | Battelle Institut E V | Inrichting voor het verstuiven van vloeistoffen. |
US4336544A (en) | 1980-08-18 | 1982-06-22 | Hewlett-Packard Company | Method and apparatus for drop-on-demand ink jet printing |
JPS5929118B2 (ja) | 1980-09-19 | 1984-07-18 | セイコーエプソン株式会社 | パラジウム・ニツケル合金メツキ液 |
CA1178191A (en) | 1980-10-06 | 1984-11-20 | Naoyoshi Maehara | Electric liquid atomizing apparatus |
US4389071A (en) | 1980-12-12 | 1983-06-21 | Hydronautics, Inc. | Enhancing liquid jet erosion |
US4474251A (en) | 1980-12-12 | 1984-10-02 | Hydronautics, Incorporated | Enhancing liquid jet erosion |
US4374707A (en) | 1981-03-19 | 1983-02-22 | Xerox Corporation | Orifice plate for ink jet printing machines |
US5862802A (en) | 1981-04-03 | 1999-01-26 | Forrest M. Bird | Ventilator having an oscillatory inspiratory phase and method |
US4454877A (en) | 1981-05-26 | 1984-06-19 | Andrew Boettner | Portable nebulizer or mist producing device |
NL8202263A (nl) | 1981-06-06 | 1983-01-03 | Rowenta Werke Gmbh | Ultrasonore respirator. |
US4408719A (en) | 1981-06-17 | 1983-10-11 | Last Anthony J | Sonic liquid atomizer |
US4475113A (en) | 1981-06-18 | 1984-10-02 | International Business Machines | Drop-on-demand method and apparatus using converging nozzles and high viscosity fluids |
JPS5861857A (ja) | 1981-10-09 | 1983-04-13 | Matsushita Electric Works Ltd | 液体噴霧器 |
AU553251B2 (en) | 1981-10-15 | 1986-07-10 | Matsushita Electric Industrial Co., Ltd. | Arrangement for ejecting liquid |
US4474326A (en) | 1981-11-24 | 1984-10-02 | Tdk Electronics Co., Ltd. | Ultrasonic atomizing device |
US4605167A (en) | 1982-01-18 | 1986-08-12 | Matsushita Electric Industrial Company, Limited | Ultrasonic liquid ejecting apparatus |
US5073484A (en) | 1982-03-09 | 1991-12-17 | Bio-Metric Systems, Inc. | Quantitative analysis apparatus and method |
DE3311956A1 (de) | 1982-03-31 | 1983-10-13 | Ricoh Co., Ltd., Tokyo | Farbstrahl-druckerkopf |
US4566452A (en) | 1982-07-12 | 1986-01-28 | American Hospital Supply Corporation | Nebulizer |
JPS5912775A (ja) | 1982-07-14 | 1984-01-23 | Matsushita Electric Ind Co Ltd | 霧化ポンプユニツト |
DE3229921A1 (de) | 1982-08-11 | 1984-02-16 | Linde Ag, 6200 Wiesbaden | Verfahren zum gleichzeitigen befuellen von mehreren mit acetylen gefuellten flaschen mit loesungsmitteln |
US5258041A (en) | 1982-09-29 | 1993-11-02 | Bio-Metric Systems, Inc. | Method of biomolecule attachment to hydrophobic surfaces |
US5002582A (en) | 1982-09-29 | 1991-03-26 | Bio-Metric Systems, Inc. | Preparation of polymeric surfaces via covalently attaching polymers |
US5512329A (en) | 1982-09-29 | 1996-04-30 | Bsi Corporation | Substrate surface preparation |
US4722906A (en) | 1982-09-29 | 1988-02-02 | Bio-Metric Systems, Inc. | Binding reagents and methods |
US5217492A (en) | 1982-09-29 | 1993-06-08 | Bio-Metric Systems, Inc. | Biomolecule attachment to hydrophobic surfaces |
US4973493A (en) | 1982-09-29 | 1990-11-27 | Bio-Metric Systems, Inc. | Method of improving the biocompatibility of solid surfaces |
IT1156090B (it) | 1982-10-26 | 1987-01-28 | Olivetti & Co Spa | Metodo e dispositivo di stampa a getto d inchiostro |
US4512341A (en) | 1982-11-22 | 1985-04-23 | Lester Victor E | Nebulizer with capillary feed |
US4632311A (en) | 1982-12-20 | 1986-12-30 | Matsushita Electric Industrial Co., Ltd. | Atomizing apparatus employing a capacitive piezoelectric transducer |
DE3320441A1 (de) | 1983-06-06 | 1984-12-06 | Siemens AG, 1000 Berlin und 8000 München | Mit fluessigkeitstroepfchen arbeitendes schreibgeraet mit an beiden enden starr mit einer duesenplatte verbundenen stabfoermigen piezoelektrischen wandlern |
ATE27405T1 (de) | 1983-08-02 | 1987-06-15 | Trutek Research Inc | Beatmungsventil. |
US4544933A (en) | 1983-09-20 | 1985-10-01 | Siemens Aktiengesellschaft | Apparatus and method for ink droplet ejection for a printer |
EP0156409A3 (en) | 1984-02-23 | 1986-06-25 | Jean Michel Anthony | Device for moistening parts of the human body |
US4593291A (en) | 1984-04-16 | 1986-06-03 | Exxon Research And Engineering Co. | Method for operating an ink jet device to obtain high resolution printing |
EP0173334B1 (en) | 1984-08-29 | 1989-11-23 | Omron Tateisi Electronics Co. | Ultrasonic atomizer |
US4628890A (en) | 1984-08-31 | 1986-12-16 | Freeman Winifer W | Fuel atomizer |
EP0174033B1 (en) | 1984-09-07 | 1991-03-27 | OMRON Corporation | Oscillating construction for an ultrasonic atomizing inhaler |
US4582654A (en) | 1984-09-12 | 1986-04-15 | Varian Associates, Inc. | Nebulizer particularly adapted for analytical purposes |
US4826759A (en) | 1984-10-04 | 1989-05-02 | Bio-Metric Systems, Inc. | Field assay for ligands |
NZ209900A (en) | 1984-10-16 | 1989-08-29 | Univ Auckland | Automatic inhaler |
US4550325A (en) | 1984-12-26 | 1985-10-29 | Polaroid Corporation | Drop dispensing device |
DE3500985A1 (de) | 1985-01-14 | 1986-07-17 | Siemens AG, 1000 Berlin und 8000 München | Anordnung zur erzeugung von einzeltroepfchen in tintenschreibeinrichtungen |
SE447318B (sv) | 1985-05-21 | 1986-11-03 | Nils Goran Stemme | Integrerad halvledarkrets med fog av termiskt isolerande fogemne, sett att framstella kretsen samt dess anvendning i en flodesmetare |
DE3523947A1 (de) | 1985-07-04 | 1987-01-08 | Draegerwerk Ag | Narkosemittelverdunster mit auswechselbarer verdunsterkammer |
DE3524701A1 (de) | 1985-07-11 | 1987-01-15 | Bosch Gmbh Robert | Ultraschallzerstaeuberduese |
US4613326A (en) | 1985-07-12 | 1986-09-23 | Becton, Dickinson And Company | Two-component medication syringe assembly |
US4659014A (en) | 1985-09-05 | 1987-04-21 | Delavan Corporation | Ultrasonic spray nozzle and method |
US4702418A (en) | 1985-09-09 | 1987-10-27 | Piezo Electric Products, Inc. | Aerosol dispenser |
ES2025054B3 (es) | 1985-12-02 | 1992-03-16 | Marco Alfredo Ganser | Aparato para inyeccion de fuel para motores de combustion interna. |
US4753579A (en) | 1986-01-22 | 1988-06-28 | Piezo Electric Products, Inc. | Ultrasonic resonant device |
US4678680A (en) | 1986-02-20 | 1987-07-07 | Xerox Corporation | Corrosion resistant aperture plate for ink jet printers |
JPS62221352A (ja) | 1986-03-22 | 1987-09-29 | 株式会社新素材総合研究所 | 酸素による薬液の変質を防止する薬液入りプラスチック容器の製造方法 |
SE8601351D0 (sv) | 1986-03-24 | 1986-03-24 | Nilsson Sven Erik | Styrd administration av fysiologiskt aktiva emnen |
US4658269A (en) | 1986-06-02 | 1987-04-14 | Xerox Corporation | Ink jet printer with integral electrohydrodynamic electrodes and nozzle plate |
US4849303A (en) | 1986-07-01 | 1989-07-18 | E. I. Du Pont De Nemours And Company | Alloy coatings for electrical contacts |
US4799622A (en) | 1986-08-05 | 1989-01-24 | Tao Nenryo Kogyo Kabushiki Kaisha | Ultrasonic atomizing apparatus |
DE3627222A1 (de) | 1986-08-11 | 1988-02-18 | Siemens Ag | Ultraschall-taschenzerstaeubergeraet |
US4819834A (en) | 1986-09-09 | 1989-04-11 | Minnesota Mining And Manufacturing Company | Apparatus and methods for delivering a predetermined amount of a pressurized fluid |
US4871489A (en) | 1986-10-07 | 1989-10-03 | Corning Incorporated | Spherical particles having narrow size distribution made by ultrasonic vibration |
US4979959A (en) | 1986-10-17 | 1990-12-25 | Bio-Metric Systems, Inc. | Biocompatible coating for solid surfaces |
US5263992A (en) | 1986-10-17 | 1993-11-23 | Bio-Metric Systems, Inc. | Biocompatible device with covalently bonded biocompatible agent |
DE3636669C2 (de) | 1986-10-28 | 2001-08-16 | Siemens Ag | Anordnung zur Zufuhr von Aerosol zu den Luftwegen und/oder Lungen eines Patienten |
DE3637631C1 (de) | 1986-11-05 | 1987-08-20 | Philips Patentverwaltung | Verfahren zum Aufbringen kleiner schmelzfluessiger,tropfenfoermiger Lotmengen aus einer Duese auf zu benetzende Flaechen und Vorrichtung zur Durchfuehrung des Verfahrens |
US4976259A (en) * | 1986-12-22 | 1990-12-11 | Mountain Medical Equipment, Inc. | Ultrasonic nebulizer |
DE3760650D1 (en) | 1987-03-17 | 1989-11-09 | Lechler Gmbh & Co Kg | Ultrasonic liquid sprayer |
JPS63230957A (ja) | 1987-03-20 | 1988-09-27 | Hitachi Ltd | 液体微粒化装置 |
US4850534A (en) | 1987-05-30 | 1989-07-25 | Tdk Corporation | Ultrasonic wave nebulizer |
DE3775054D1 (de) | 1987-06-16 | 1992-01-16 | Akzo Nv | Zweikammer-spritze und herstellungsverfahren. |
US5522382A (en) | 1987-06-26 | 1996-06-04 | Rescare Limited | Device and method for treating obstructed breathing having a delay/ramp feature |
US5199424A (en) | 1987-06-26 | 1993-04-06 | Sullivan Colin E | Device for monitoring breathing during sleep and control of CPAP treatment that is patient controlled |
IL86799A (en) | 1987-07-02 | 1993-03-15 | Kabi Pharmacia Ab | Method and device for injection |
US5080093A (en) | 1987-07-08 | 1992-01-14 | Vortran Medical Technology, Inc. | Intermittant signal actuated nebulizer |
US5322057A (en) | 1987-07-08 | 1994-06-21 | Vortran Medical Technology, Inc. | Intermittent signal actuated nebulizer synchronized to operate in the exhalation phase, and its method of use |
US5388571A (en) | 1987-07-17 | 1995-02-14 | Roberts; Josephine A. | Positive-pressure ventilator system with controlled access for nebulizer component servicing |
US4805609A (en) | 1987-07-17 | 1989-02-21 | Josephine A. Roberts | Pressurized ventilation system for patients |
DE3724629A1 (de) | 1987-07-22 | 1989-02-02 | Siemens Ag | Piezoelektrisch anregbares resonanzsystem |
US5139016A (en) | 1987-08-07 | 1992-08-18 | Sorin Biomedica S.P.A. | Process and device for aerosol generation for pulmonary ventilation scintigraphy |
US5063921A (en) * | 1987-11-12 | 1991-11-12 | Cimco, Inc. | Nebulizer heater |
FI82808C (fi) | 1987-12-31 | 1991-04-25 | Etelae Haemeen Keuhkovammayhdi | Ultraljudfinfoerdelningsanordning. |
DE3808308A1 (de) | 1988-03-12 | 1989-09-21 | Merck Patent Gmbh | Oeffnungshilfe fuer ampullen |
US5115971A (en) | 1988-09-23 | 1992-05-26 | Battelle Memorial Institute | Nebulizer device |
NL8801260A (nl) | 1988-05-16 | 1989-12-18 | Mobacc Bv | Sproeikop voor een spuitbus. |
DE3818682A1 (de) | 1988-06-01 | 1989-12-21 | Deussen Stella Kg | Ampulle |
US5201322A (en) | 1988-08-17 | 1993-04-13 | Elf Atochem North America, Inc. | Device for detecting air flow through a passageway |
US4922901A (en) | 1988-09-08 | 1990-05-08 | R. J. Reynolds Tobacco Company | Drug delivery articles utilizing electrical energy |
DE3916840A1 (de) | 1988-09-21 | 1990-03-29 | Bernd Hansen | Ampulle |
US5511726A (en) | 1988-09-23 | 1996-04-30 | Battelle Memorial Institute | Nebulizer device |
US5021701A (en) | 1988-10-20 | 1991-06-04 | Tdk Corporation | Piezoelectric vibrator mounting system for a nebulizer |
USD312209S (en) | 1988-10-21 | 1990-11-20 | Becton, Dickinson And Company | Dispensing vial or the like |
EP0373237A1 (de) | 1988-12-13 | 1990-06-20 | Siemens Aktiengesellschaft | Inhalationsgerät, insbesondere Taschen-Inhalationsgerät |
SE466684B (sv) | 1989-03-07 | 1992-03-23 | Draco Ab | Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator |
JPH02269058A (ja) | 1989-03-14 | 1990-11-02 | Seiko Epson Corp | レーリーモード弾性表面波による液滴ジェット装置 |
EP0424532A4 (en) | 1989-04-14 | 1991-12-04 | Azerbaidzhansky Politekhnichesky Institut Imeni Ch. Ildryma | Device for ultrasonic dispersion of a liquid medium |
US5022587A (en) | 1989-06-07 | 1991-06-11 | Hochstein Peter A | Battery powered nebulizer |
US5086785A (en) | 1989-08-10 | 1992-02-11 | Abrams/Gentille Entertainment Inc. | Angular displacement sensors |
US5562608A (en) | 1989-08-28 | 1996-10-08 | Biopulmonics, Inc. | Apparatus for pulmonary delivery of drugs with simultaneous liquid lavage and ventilation |
US5024733A (en) | 1989-08-29 | 1991-06-18 | At&T Bell Laboratories | Palladium alloy electroplating process |
US5007419A (en) | 1989-09-25 | 1991-04-16 | Allan Weinstein | Inhaler device |
US5227168A (en) | 1989-11-21 | 1993-07-13 | Bruce Barber | Method of treating a wound |
US5152456A (en) | 1989-12-12 | 1992-10-06 | Bespak, Plc | Dispensing apparatus having a perforate outlet member and a vibrating device |
US5002048A (en) | 1989-12-12 | 1991-03-26 | Makiej Jr Walter J | Inhalation device utilizing two or more aerosol containers |
CH680546A5 (ja) | 1989-12-15 | 1992-09-15 | Klaus Weigelt Dr Ing | |
US4971665A (en) | 1989-12-18 | 1990-11-20 | Eastman Kodak Company | Method of fabricating orifice plates with reusable mandrel |
US5016024A (en) | 1990-01-09 | 1991-05-14 | Hewlett-Packard Company | Integral ink jet print head |
US4954225A (en) | 1990-01-10 | 1990-09-04 | Dynamics Research Corporation | Method for making nozzle plates |
ES2042093T3 (es) | 1990-02-07 | 1993-12-01 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Jeringa de doble camara y procedimiento de empleo. |
SG45171A1 (en) | 1990-03-21 | 1998-01-16 | Boehringer Ingelheim Int | Atomising devices and methods |
US4993411A (en) * | 1990-04-06 | 1991-02-19 | Medway | Ultrasonic oxygen humidifier |
US5122116A (en) | 1990-04-24 | 1992-06-16 | Science Incorporated | Closed drug delivery system |
FR2662672B1 (fr) | 1990-05-31 | 1992-08-21 | Aerosols & Bouchage | Dispensateur de melange. |
GB9015077D0 (en) | 1990-07-09 | 1990-08-29 | Riker Laboratories Inc | Inhaler |
US5309135A (en) | 1990-07-13 | 1994-05-03 | Langford Gordon B | Flexible potentiometer in a horn control system |
US5157372A (en) | 1990-07-13 | 1992-10-20 | Langford Gordon B | Flexible potentiometer |
FR2665849B1 (fr) | 1990-08-20 | 1995-03-24 | Dynamad | Dispositif ultrasonique pour la production en continu de particules. |
US5086765A (en) | 1990-08-29 | 1992-02-11 | Walter Levine | Nebulizer |
USD327008S (en) | 1990-08-29 | 1992-06-16 | True Products Sampling, Inc. | Cosmetic sample container |
US5115803A (en) | 1990-08-31 | 1992-05-26 | Minnesota Mining And Manufacturing Company | Aerosol actuator providing increased respirable fraction |
GB9020555D0 (en) | 1990-09-20 | 1990-10-31 | Bespak Plc | Dispensing apparatus |
DE69117127T2 (de) | 1990-10-11 | 1996-11-07 | Toda Koji | Ultraschall-Zerstäuber |
CA2027690A1 (en) | 1990-10-18 | 1992-04-19 | Christian Laing | Plastic ampul |
US5129579A (en) | 1990-10-25 | 1992-07-14 | Sun Microsystems, Inc. | Vacuum attachment for electronic flux nozzle |
GB9023281D0 (en) | 1990-10-25 | 1990-12-05 | Riker Laboratories Inc | Inhaler |
DE69127826T2 (de) | 1990-12-17 | 1998-04-09 | Minnesota Mining & Mfg | Inhalationsgerät |
US5062419A (en) | 1991-01-07 | 1991-11-05 | Rider Donald L | Nebulizer with valved "T" assembly |
US5147073A (en) | 1991-02-11 | 1992-09-15 | Spruhventile Gmbh | Fluid pump dispenser for pharmaceutical use |
US5217148A (en) | 1991-02-11 | 1993-06-08 | Spruhventile Gmbh | Pharmaceutical pump dispenser |
WO1994016758A1 (en) | 1991-03-05 | 1994-08-04 | Miris Medical Corporation | A medication cassette for an automatic aerosol medication delivery system |
US5392768A (en) | 1991-03-05 | 1995-02-28 | Aradigm | Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval |
US5404871A (en) | 1991-03-05 | 1995-04-11 | Aradigm | Delivery of aerosol medications for inspiration |
US5186164A (en) | 1991-03-15 | 1993-02-16 | Puthalath Raghuprasad | Mist inhaler |
WO1992017231A1 (en) | 1991-03-28 | 1992-10-15 | Innomed, Inc. | Microelectronic inhaler having a counter and timer |
US5348189A (en) | 1991-04-10 | 1994-09-20 | Bespak Plc | Air purge pump dispenser |
US5993805A (en) | 1991-04-10 | 1999-11-30 | Quadrant Healthcare (Uk) Limited | Spray-dried microparticles and their use as therapeutic vehicles |
US5164740A (en) | 1991-04-24 | 1992-11-17 | Yehuda Ivri | High frequency printing mechanism |
US5938117A (en) | 1991-04-24 | 1999-08-17 | Aerogen, Inc. | Methods and apparatus for dispensing liquids as an atomized spray |
US6540154B1 (en) | 1991-04-24 | 2003-04-01 | Aerogen, Inc. | Systems and methods for controlling fluid feed to an aerosol generator |
US6629646B1 (en) | 1991-04-24 | 2003-10-07 | Aerogen, Inc. | Droplet ejector with oscillating tapered aperture |
DE69210096T2 (de) | 1991-05-27 | 1996-09-19 | Tdk Corp | Ultraschallzerstäuber |
JPH0614756Y2 (ja) | 1991-06-26 | 1994-04-20 | 株式会社アルテ | 組み立て式の2室式容器兼用注射器 |
KR100246082B1 (ko) | 1991-07-02 | 2000-04-01 | 인헤일, 인코오포레이티드 | 에어로졸화된약제를전달하는방법및장치 |
WO1993001404A1 (en) | 1991-07-08 | 1993-01-21 | Yehuda Ivri | Ultrasonic fluid ejector |
DE4124032A1 (de) | 1991-07-19 | 1993-01-21 | Bosch Gmbh Robert | Messelement |
US5180482A (en) | 1991-07-22 | 1993-01-19 | At&T Bell Laboratories | Thermal annealing of palladium alloys |
US5230496A (en) | 1991-08-06 | 1993-07-27 | Med-Safe Systems, Inc. | Pole mounting clamp |
US5601077A (en) | 1991-08-07 | 1997-02-11 | Becton, Dickinson And Company | Nasal syringe sprayer with removable dose limiting structure |
DE4127650C1 (ja) | 1991-08-21 | 1993-02-25 | Arzneimittel Gmbh Apotheker Vetter & Co Ravensburg, 7980 Ravensburg, De | |
HU216998B (hu) | 1991-08-29 | 1999-11-29 | Broncho-Air Medizintechnik Ag. | Orvosi készülék aeroszóladagok inhalálásához |
US5170782A (en) * | 1991-09-12 | 1992-12-15 | Devilbiss Health Care, Inc. | Medicament nebulizer with improved aerosol chamber |
ATE155695T1 (de) | 1991-11-07 | 1997-08-15 | Ritzau Pari Werk Gmbh Paul | Vernebler insbesondere zur anwendung in geräten für die inhalationstherapie |
GB2265845B (en) | 1991-11-12 | 1996-05-01 | Medix Ltd | A nebuliser and nebuliser control system |
US5518179A (en) | 1991-12-04 | 1996-05-21 | The Technology Partnership Limited | Fluid droplets production apparatus and method |
DE69218901T2 (de) * | 1991-12-10 | 1997-07-17 | Tdk Corp | Ultraschallzerstäuber |
DE69328523T2 (de) | 1992-02-13 | 2000-09-21 | Surmodics, Inc. | Immobilisierung eines chemischen spezies in einer vernetzten matrix |
US5355872B1 (en) | 1992-03-04 | 1998-10-20 | John H Riggs | Low flow rate nebulizer apparatus and method of nebulization |
US5186166A (en) | 1992-03-04 | 1993-02-16 | Riggs John H | Powder nebulizer apparatus and method of nebulization |
JPH05271980A (ja) | 1992-03-30 | 1993-10-19 | Yazaki Corp | パラジウム−ニッケル合金メッキ液 |
WO1993020949A1 (en) | 1992-04-09 | 1993-10-28 | Omron Corporation | Ultrasonic atomizer, ultrasonic inhalator and method of controlling same |
EP0933138B1 (en) | 1992-04-09 | 2004-03-03 | Omron Healthcare Co., Ltd. | Ultrasonic atomizer |
GB9207940D0 (en) | 1992-04-10 | 1992-05-27 | Alcan Int Ltd | Motors |
US5248087A (en) | 1992-05-08 | 1993-09-28 | Dressler John L | Liquid droplet generator |
US5512474A (en) | 1992-05-29 | 1996-04-30 | Bsi Corporation | Cell culture support containing a cell adhesion factor and a positively-charged molecule |
US5431155A (en) | 1992-06-03 | 1995-07-11 | Elettro Plastica S.P.A. | Single-dose nasal dispenser for atomized liquid drugs |
JP3178945B2 (ja) | 1992-08-25 | 2001-06-25 | 日本碍子株式会社 | インクジェットプリントヘッド |
DE4230645C2 (de) | 1992-09-12 | 1996-03-07 | Bernd Hansen | Ampulle |
US5372126A (en) | 1992-09-14 | 1994-12-13 | Blau; Anthony D. | Pulmonary sampling chamber |
US5392769A (en) * | 1992-10-06 | 1995-02-28 | Vinatroics Division | One-way valve |
US5357946A (en) | 1992-10-19 | 1994-10-25 | Sherwood Medical Company | Ventilator manifold with accessory access port and adaptors therefore |
US5445141A (en) | 1992-10-19 | 1995-08-29 | Sherwood Medical Company | Respiratory support system |
DE69312628T2 (de) | 1992-10-27 | 1998-02-12 | Canon Kk | Verfahren zum Fördern von Flüssigkeiten |
US5313955A (en) | 1992-10-30 | 1994-05-24 | Rodder Jerome A | Pulmonary flow head |
GB2272389B (en) | 1992-11-04 | 1996-07-24 | Bespak Plc | Dispensing apparatus |
US5414075A (en) | 1992-11-06 | 1995-05-09 | Bsi Corporation | Restrained multifunctional reagent for surface modification |
US5346132A (en) | 1992-11-12 | 1994-09-13 | Gary S. Hahn | Mist generator |
GB9225098D0 (en) | 1992-12-01 | 1993-01-20 | Coffee Ronald A | Charged droplet spray mixer |
US5452711A (en) | 1992-12-24 | 1995-09-26 | Exar Corporation | Small form factor atomizer |
US5449502A (en) | 1992-12-30 | 1995-09-12 | Sanden Corp. | Sterilizing apparatus utilizing ultrasonic vibration |
US5342011A (en) | 1993-01-19 | 1994-08-30 | Sherwood Medical Company | Fluid container attachment adaptor for an ambulatory fluid delivery system |
WO1994016756A1 (en) | 1993-01-29 | 1994-08-04 | Miris Medical Corporation | Intrapulmonary delivery of hormones |
US5724957A (en) | 1993-01-29 | 1998-03-10 | Aradigm Corporation | Intrapulmonary delivery of narcotics |
US6012450A (en) | 1993-01-29 | 2000-01-11 | Aradigm Corporation | Intrapulmonary delivery of hematopoietic drug |
US5558085A (en) | 1993-01-29 | 1996-09-24 | Aradigm Corporation | Intrapulmonary delivery of peptide drugs |
US5350116A (en) | 1993-03-01 | 1994-09-27 | Bespak Plc | Dispensing apparatus |
US5458289A (en) | 1993-03-01 | 1995-10-17 | Bespak Plc | Liquid dispensing apparatus with reduced clogging |
US5279568A (en) | 1993-04-30 | 1994-01-18 | Spruhventile Gmbh | Pharmaceutical pump dispenser for fluid suspensions and fluid mixtures |
US5303854A (en) | 1993-03-08 | 1994-04-19 | Spruhventile Gmbh | Pharmaceutical pump dispenser having hydraulically closed outlet port |
GB9305975D0 (en) | 1993-03-23 | 1993-05-12 | Minnesota Mining & Mfg | Metered-dose aerosol valves |
US5383906A (en) | 1993-05-12 | 1995-01-24 | Burchett; Mark T. | Nursing bottle with medication dispenser |
US5396883A (en) | 1993-05-18 | 1995-03-14 | Knupp; Jacob E. | Nebulizer valve assembly for use in a ventilation circuit |
US5497763A (en) | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
US5709202A (en) | 1993-05-21 | 1998-01-20 | Aradigm Corporation | Intrapulmonary delivery of aerosolized formulations |
FR2705911B1 (fr) | 1993-06-02 | 1995-08-11 | Oreal | Appareil de nébulisation piézoélectrique. |
GB9311892D0 (en) | 1993-06-09 | 1993-07-28 | Glaxo Wellcome Australia Ltd | Device |
GB9312984D0 (en) | 1993-06-23 | 1993-08-04 | Bespak Plc | Atomising dispenser |
ES2171455T3 (es) | 1993-06-29 | 2002-09-16 | Ponwell Entpr Ltd | Dispensador. |
US5388574A (en) | 1993-07-29 | 1995-02-14 | Ingebrethsen; Bradley J. | Aerosol delivery article |
US5437267A (en) | 1993-08-03 | 1995-08-01 | Weinstein; Allan | Device for delivering aerosol to the nasal membranes and method of use |
CH686872A5 (de) | 1993-08-09 | 1996-07-31 | Disetronic Ag | Medizinisches Inhalationsgeraet. |
US5426458A (en) | 1993-08-09 | 1995-06-20 | Hewlett-Packard Corporation | Poly-p-xylylene films as an orifice plate coating |
US5918637A (en) | 1993-08-16 | 1999-07-06 | Fleischman; William H. | Plates perforated with venturi-like orifices |
US5415161A (en) | 1993-09-15 | 1995-05-16 | Ryder; Steven L. | Intermittant demand aerosol control device |
GB9324250D0 (en) | 1993-11-25 | 1994-01-12 | Minnesota Mining & Mfg | Inhaler |
GB9412669D0 (en) | 1994-06-23 | 1994-08-10 | The Technology Partnership Plc | Liquid spray apparatus |
US5752502A (en) | 1993-12-16 | 1998-05-19 | King; Russell Wayne | General purpose aerosol inhalation apparatus |
US5489266A (en) | 1994-01-25 | 1996-02-06 | Becton, Dickinson And Company | Syringe assembly and method for lyophilizing and reconstituting injectable medication |
US5632878A (en) | 1994-02-01 | 1997-05-27 | Fet Engineering, Inc. | Method for manufacturing an electroforming mold |
US5579757A (en) | 1994-02-02 | 1996-12-03 | Baxter International, Inc. | Anti-siphon flow restricter for a nebulizer |
US5479920A (en) | 1994-03-01 | 1996-01-02 | Vortran Medical Technology, Inc. | Breath actuated medicinal aerosol delivery apparatus |
US5664557A (en) | 1994-03-10 | 1997-09-09 | Respiratory Delivery Systems, Inc. | Releasably engageable coupling for an inhaler |
USD375352S (en) | 1994-03-14 | 1996-11-05 | Columbia Laboratories, Inc. | Dispensing vial for feminine hygiene products |
US5435282A (en) * | 1994-05-19 | 1995-07-25 | Habley Medical Technology Corporation | Nebulizer |
GB9410658D0 (en) | 1994-05-27 | 1994-07-13 | Electrosols Ltd | Dispensing device |
USD362390S (en) | 1994-06-02 | 1995-09-19 | Automatic Liquid Packaging, Inc. | Hermetically sealed vial |
US5516043A (en) | 1994-06-30 | 1996-05-14 | Misonix Inc. | Ultrasonic atomizing device |
US5666946A (en) | 1994-07-13 | 1997-09-16 | Respirogenics Corporation | Apparatus for delivering drugs to the lungs |
FR2722765B1 (fr) | 1994-07-25 | 1996-08-23 | Oreal | Recipient permettant le stockage d'au moins deux produits, le melange de ces produits et la distribution du melange ainsi obtenu |
US5664706A (en) | 1994-10-13 | 1997-09-09 | Bespak Plc | Apparatus for dispensing liquid in aerosol spray form |
AU128844S (en) | 1994-10-21 | 1996-12-05 | Glaxo Wellcome Australia Ltd | Ampoule |
GB9421687D0 (en) | 1994-10-27 | 1994-12-14 | Aid Medic Ltd | Dosimetric spacer |
US5560837A (en) | 1994-11-08 | 1996-10-01 | Hewlett-Packard Company | Method of making ink-jet component |
US5707818A (en) | 1994-12-13 | 1998-01-13 | Bsi Corporation | Device and method for simultaneously performing multiple competitive immunoassays |
US5582330A (en) | 1994-12-28 | 1996-12-10 | Allergan, Inc. | Specific volume dispenser |
US5588166A (en) | 1995-01-04 | 1996-12-31 | Burnett; John | Medical attachment device |
US5685491A (en) | 1995-01-11 | 1997-11-11 | Amtx, Inc. | Electroformed multilayer spray director and a process for the preparation thereof |
GB2298406B (en) | 1995-02-21 | 1998-05-06 | Bespak Plc | Dual component dispensing apparatus |
NO950760L (no) | 1995-02-28 | 1996-08-29 | Elkem Materials | Fremgangsmåte for fremstilling av alkylhalosilaner |
EP0730858B1 (de) | 1995-03-09 | 1999-03-10 | Bernd Dipl.-Ing. Hansen | Flasche aus Kunststoff und Verfahren zu ihrer Herstellung |
US5970974A (en) | 1995-03-14 | 1999-10-26 | Siemens Aktiengesellschaft | Dosating unit for an ultrasonic atomizer device |
ES2140069T3 (es) | 1995-03-14 | 2000-02-16 | Siemens Ag | Dispositivo atomizador ultrasonico con unidad dosificadora de precision desmontable. |
US5503628A (en) | 1995-03-15 | 1996-04-02 | Jettek, Inc. | Patient-fillable hypodermic jet injector |
US5533497A (en) | 1995-03-27 | 1996-07-09 | Ryder; Steven L. | Sidestream aerosol generator and method in variable positions |
US6085740A (en) | 1996-02-21 | 2000-07-11 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US6014970A (en) | 1998-06-11 | 2000-01-18 | Aerogen, Inc. | Methods and apparatus for storing chemical compounds in a portable inhaler |
US6427682B1 (en) | 1995-04-05 | 2002-08-06 | Aerogen, Inc. | Methods and apparatus for aerosolizing a substance |
US5586550A (en) | 1995-08-31 | 1996-12-24 | Fluid Propulsion Technologies, Inc. | Apparatus and methods for the delivery of therapeutic liquids to the respiratory system |
US5758637A (en) * | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US6782886B2 (en) | 1995-04-05 | 2004-08-31 | Aerogen, Inc. | Metering pumps for an aerosolizer |
US6205999B1 (en) | 1995-04-05 | 2001-03-27 | Aerogen, Inc. | Methods and apparatus for storing chemical compounds in a portable inhaler |
US20020121274A1 (en) | 1995-04-05 | 2002-09-05 | Aerogen, Inc. | Laminated electroformed aperture plate |
US5474059A (en) | 1995-04-08 | 1995-12-12 | Cooper; Guy F. | Aerosol dispensing apparatus for dispensing a medicated vapor into the lungs of a patient |
US5657926A (en) | 1995-04-13 | 1997-08-19 | Toda; Kohji | Ultrasonic atomizing device |
US6029666A (en) | 1995-05-02 | 2000-02-29 | Alexander Aloy | Device for delivering a ventilation gas |
JP3318578B2 (ja) | 1995-05-26 | 2002-08-26 | サーモディックス,インコーポレイティド | 内皮化を促進するための方法及び移植用製品 |
JP3320261B2 (ja) | 1995-06-01 | 2002-09-03 | 株式会社ユニシアジェックス | 吸入式投薬器 |
US5609798A (en) | 1995-06-07 | 1997-03-11 | Msp Corporation | High output PSL aerosol generator |
US5654007A (en) | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
US5584285A (en) | 1995-06-07 | 1996-12-17 | Salter Labs | Breathing circuit apparatus for a nebulizer |
US5829723A (en) | 1995-06-28 | 1998-11-03 | Medex, Inc. | Medical device mounting structure |
US5904773A (en) | 1995-08-11 | 1999-05-18 | Atotech Usa, Inc. | Fluid delivery apparatus |
US6000396A (en) | 1995-08-17 | 1999-12-14 | University Of Florida | Hybrid microprocessor controlled ventilator unit |
SE9502957D0 (sv) | 1995-08-28 | 1995-08-28 | Pharmacia Ab | Device for displacing a member in a container |
US5639851A (en) | 1995-10-02 | 1997-06-17 | Ethicon, Inc. | High strength, melt processable, lactide-rich, poly(lactide-CO-P-dioxanone) copolymers |
JP3317827B2 (ja) | 1995-10-09 | 2002-08-26 | 株式会社ユニシアジェックス | 投薬器 |
US6254219B1 (en) | 1995-10-25 | 2001-07-03 | Hewlett-Packard Company | Inkjet printhead orifice plate having related orifices |
US6123413A (en) | 1995-10-25 | 2000-09-26 | Hewlett-Packard Company | Reduced spray inkjet printhead orifice |
US5714360A (en) | 1995-11-03 | 1998-02-03 | Bsi Corporation | Photoactivatable water soluble cross-linking agents containing an onium group |
US5807335A (en) | 1995-12-22 | 1998-09-15 | Science Incorporated | Fluid delivery device with conformable ullage and fill assembly |
FR2743313B1 (fr) | 1996-01-04 | 1998-02-06 | Imra Europe Sa | Dispositif de pulverisation a rendement eleve notamment d'eau sous forme de micro-gouttelettes |
US6026809A (en) | 1996-01-25 | 2000-02-22 | Microdose Technologies, Inc. | Inhalation device |
US5823179A (en) | 1996-02-13 | 1998-10-20 | 1263152 Ontario Inc. | Nebulizer apparatus and method |
USD392184S (en) | 1996-02-21 | 1998-03-17 | Automatic Liquid Packaging, Inc. | Vial with a frangible closure |
FR2746656B1 (fr) | 1996-03-26 | 1999-05-28 | System Assistance Medical | Nebuliseur a capteur de pression |
US5790151A (en) | 1996-03-27 | 1998-08-04 | Imaging Technology International Corp. | Ink jet printhead and method of making |
SE9601719D0 (sv) | 1996-05-06 | 1996-05-06 | Siemens Elema Ab | Doserare för tillförsel av tillsatsgas eller vätska till andningsgas vid anestesiapparat eller ventilator |
AUPN976496A0 (en) | 1996-05-10 | 1996-05-30 | Glaxo Wellcome Australia Ltd | Unit dose dispensing device |
US5976344A (en) | 1996-05-10 | 1999-11-02 | Lucent Technologies Inc. | Composition for electroplating palladium alloys and electroplating process using that composition |
JP3418507B2 (ja) | 1996-08-07 | 2003-06-23 | ワイケイケイ株式会社 | 圧電振動制御方法 |
AUPO247496A0 (en) | 1996-09-23 | 1996-10-17 | Resmed Limited | Assisted ventilation to match patient respiratory need |
US5775506A (en) | 1996-09-25 | 1998-07-07 | Abbott Laboratories | Pharmaceutical ampul |
DE19647947A1 (de) | 1996-11-20 | 1998-05-28 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
AUPP855099A0 (en) | 1999-02-09 | 1999-03-04 | Resmed Limited | Gas delivery connection assembly |
US5954268A (en) | 1997-03-03 | 1999-09-21 | Joshi; Ashok V. | Fluid delivery system |
US5948483A (en) | 1997-03-25 | 1999-09-07 | The Board Of Trustees Of The University Of Illinois | Method and apparatus for producing thin film and nanoparticle deposits |
AU739944B2 (en) | 1997-05-16 | 2001-10-25 | Resmed Limited | Nasal ventilation as a treatment for stroke |
US6055869A (en) | 1997-06-12 | 2000-05-02 | Stemme; Erik | Lift force fluid flow sensor for measuring fluid flow velocities |
US5839617A (en) | 1997-07-29 | 1998-11-24 | Owens-Illinois Closure Inc. | Pump dispenser |
US6045215A (en) | 1997-08-28 | 2000-04-04 | Hewlett-Packard Company | High durability ink cartridge printhead and method for making the same |
US6145963A (en) | 1997-08-29 | 2000-11-14 | Hewlett-Packard Company | Reduced size printhead for an inkjet printer |
US6139674A (en) | 1997-09-10 | 2000-10-31 | Xerox Corporation | Method of making an ink jet printhead filter by laser ablation |
US6273342B1 (en) | 1997-10-06 | 2001-08-14 | Omron Corporation | Atomizer |
US6161536A (en) | 1997-10-08 | 2000-12-19 | Sepracor Inc. | Dosage form for aerosol administration |
US6155676A (en) | 1997-10-16 | 2000-12-05 | Hewlett-Packard Company | High-durability rhodium-containing ink cartridge printhead and method for making the same |
US6037587A (en) | 1997-10-17 | 2000-03-14 | Hewlett-Packard Company | Chemical ionization source for mass spectrometry |
US6039696A (en) | 1997-10-31 | 2000-03-21 | Medcare Medical Group, Inc. | Method and apparatus for sensing humidity in a patient with an artificial airway |
AUPP026997A0 (en) | 1997-11-07 | 1997-12-04 | Resmed Limited | Administration of cpap treatment pressure in presence of apnea |
DE69834210T2 (de) | 1997-11-19 | 2007-01-04 | Microflow Engineering S.A. | Sprühvorrichtung für einen Inhalator |
US6096011A (en) | 1998-01-29 | 2000-08-01 | Medrad, Inc. | Aseptic connector and fluid delivery system using such an aseptic connector |
US6358058B1 (en) | 1998-01-30 | 2002-03-19 | 1263152 Ontario Inc. | Aerosol dispensing inhaler training device |
US6223746B1 (en) | 1998-02-12 | 2001-05-01 | Iep Pharmaceutical Devices Inc. | Metered dose inhaler pump |
US6158431A (en) | 1998-02-13 | 2000-12-12 | Tsi Incorporated | Portable systems and methods for delivery of therapeutic material to the pulmonary system |
US6204182B1 (en) | 1998-03-02 | 2001-03-20 | Hewlett-Packard Company | In-situ fluid jet orifice |
ATE303837T1 (de) | 1998-03-05 | 2005-09-15 | Zivena Inc | Lungendosiersystem |
GB9808182D0 (en) | 1998-04-17 | 1998-06-17 | The Technology Partnership Plc | Liquid projection apparatus |
US6068148A (en) | 1998-05-26 | 2000-05-30 | Automatic Liquid Packaging, Inc. | Hermetically sealed container including a nozzle with a sealing bead |
US20020104530A1 (en) | 1998-06-11 | 2002-08-08 | Aerogen, Inc. | Piezoelectric polymer flow sensor and methods |
US6152130A (en) | 1998-06-12 | 2000-11-28 | Microdose Technologies, Inc. | Inhalation device with acoustic control |
US6142146A (en) | 1998-06-12 | 2000-11-07 | Microdose Technologies, Inc. | Inhalation device |
US6106504A (en) | 1998-07-15 | 2000-08-22 | Urrutia; Hector | Drip chamber for medical fluid delivery system |
US6182662B1 (en) | 1998-07-23 | 2001-02-06 | Mcghee Chad J. | Intravenous transport/support device |
AUPP496198A0 (en) | 1998-07-31 | 1998-08-20 | Resmed Limited | Switches with graphical display |
AUPP693398A0 (en) | 1998-11-05 | 1998-12-03 | Resmed Limited | Fault diagnosis in CPAP and NIPPV devices |
ATE344108T1 (de) | 1998-12-01 | 2006-11-15 | Microflow Eng Sa | Inhalator mit ultraschallzerstäuber dessen sprühöffnungen den maximalamplituden eines stehenden wellenmusters überlagert sind |
JP3312216B2 (ja) | 1998-12-18 | 2002-08-05 | オムロン株式会社 | 噴霧装置 |
US6163588A (en) | 1998-12-23 | 2000-12-19 | General Electric Company | Core plate and reactor internal pump differential pressure lines for a boiling water reactor |
US6116234A (en) | 1999-02-01 | 2000-09-12 | Iep Pharmaceutical Devices Inc. | Metered dose inhaler agitator |
GB2347870A (en) * | 1999-02-22 | 2000-09-20 | Sunrise Medical Hhg Inc | Medical nebuliser |
US6196218B1 (en) | 1999-02-24 | 2001-03-06 | Ponwell Enterprises Ltd | Piezo inhaler |
US6328030B1 (en) | 1999-03-12 | 2001-12-11 | Daniel E. Kidwell | Nebulizer for ventilation system |
AUPQ019899A0 (en) | 1999-05-06 | 1999-06-03 | Resmed Limited | Control of supplied pressure in assisted ventilation |
US6328033B1 (en) | 1999-06-04 | 2001-12-11 | Zohar Avrahami | Powder inhaler |
US6235177B1 (en) | 1999-09-09 | 2001-05-22 | Aerogen, Inc. | Method for the construction of an aperture plate for dispensing liquid droplets |
US6216916B1 (en) | 1999-09-16 | 2001-04-17 | Joseph S. Kanfer | Compact fluid pump |
US6530370B1 (en) | 1999-09-16 | 2003-03-11 | Instrumentation Corp. | Nebulizer apparatus |
JP3673893B2 (ja) | 1999-10-15 | 2005-07-20 | 日本碍子株式会社 | 液滴吐出装置 |
DE19962280A1 (de) | 1999-12-23 | 2001-07-12 | Draeger Medizintech Gmbh | Ultraschallvernebler |
US6968840B2 (en) | 2000-05-05 | 2005-11-29 | Aerogen, Inc. | Methods and systems for operating an aerosol generator |
US7100600B2 (en) | 2001-03-20 | 2006-09-05 | Aerogen, Inc. | Fluid filled ampoules and methods for their use in aerosolizers |
MXPA02010884A (es) | 2000-05-05 | 2003-03-27 | Aerogen Ireland Ltd | Aparato y metodo para el suministro de medicamentos al sistema respiratorio. |
US6948491B2 (en) | 2001-03-20 | 2005-09-27 | Aerogen, Inc. | Convertible fluid feed system with comformable reservoir and methods |
US7600511B2 (en) | 2001-11-01 | 2009-10-13 | Novartis Pharma Ag | Apparatus and methods for delivery of medicament to a respiratory system |
US6341732B1 (en) | 2000-06-19 | 2002-01-29 | S. C. Johnson & Son, Inc. | Method and apparatus for maintaining control of liquid flow in a vibratory atomizing device |
US6543443B1 (en) | 2000-07-12 | 2003-04-08 | Aerogen, Inc. | Methods and devices for nebulizing fluids |
US6769626B1 (en) | 2000-10-30 | 2004-08-03 | Instrumentarium Corp. | Device and method for detecting and controlling liquid supply to an apparatus discharging liquids |
IL139388A (en) * | 2000-11-01 | 2005-09-25 | Makhteshim Chem Works Ltd | Pest control sheet |
US6581595B1 (en) | 2000-11-14 | 2003-06-24 | Sensormedics Corporation | Positive airway pressure device with indirect calorimetry system |
US20020078958A1 (en) | 2000-12-21 | 2002-06-27 | Sensormedics Corporation | Infant CPAP system with airway pressure control |
DE10102846B4 (de) * | 2001-01-23 | 2012-04-12 | Pari Pharma Gmbh | Aerosolgenerator |
US6546927B2 (en) * | 2001-03-13 | 2003-04-15 | Aerogen, Inc. | Methods and apparatus for controlling piezoelectric vibration |
US6550472B2 (en) | 2001-03-16 | 2003-04-22 | Aerogen, Inc. | Devices and methods for nebulizing fluids using flow directors |
US6732944B2 (en) | 2001-05-02 | 2004-05-11 | Aerogen, Inc. | Base isolated nebulizing device and methods |
US6554201B2 (en) | 2001-05-02 | 2003-04-29 | Aerogen, Inc. | Insert molded aerosol generator and methods |
US20020162551A1 (en) | 2001-05-02 | 2002-11-07 | Litherland Craig M. | Cymbal-shaped actuator for a nebulizing element |
ATE298600T1 (de) * | 2001-10-18 | 2005-07-15 | Pari Gmbh | Inhalationstherapievorrichtung |
AU2002337478B2 (en) * | 2001-11-01 | 2008-09-04 | Aerogen (Ireland) Limited | Apparatus and method for delivery of medicaments to the respiratory system |
US6851626B2 (en) | 2002-01-07 | 2005-02-08 | Aerogen, Inc. | Methods and devices for nebulizing fluids |
CA2472644C (en) | 2002-01-07 | 2013-11-05 | Aerogen, Inc. | Devices and methods for nebulizing fluids for inhalation |
US6745770B2 (en) | 2002-01-08 | 2004-06-08 | Resmed Limited | Flow diverter for controlling the pressure and flow rate in a CPAP device |
US6845770B2 (en) | 2002-01-15 | 2005-01-25 | Aerogen, Inc. | Systems and methods for clearing aerosols from the effective anatomic dead space |
US6860268B2 (en) | 2002-02-06 | 2005-03-01 | Shelly Bohn | Pediatric ventilation mask and headgear system |
US6966174B2 (en) * | 2002-04-15 | 2005-11-22 | Paul Marius A | Integrated bypass turbojet engines for air craft and other vehicles |
US6830046B2 (en) * | 2002-04-29 | 2004-12-14 | Hewlett-Packard Development Company, L.P. | Metered dose inhaler |
US7334580B2 (en) | 2002-05-07 | 2008-02-26 | Smaldone Gerald C | Methods, devices and formulations for targeted endobronchial therapy |
ES2572770T3 (es) | 2002-05-20 | 2016-06-02 | Novartis Ag | Aparato para proporcionar pulverización para tratamiento médico y métodos |
EP3581228A1 (en) | 2003-02-21 | 2019-12-18 | ResMed Pty Ltd | Nasal assembly for delivering breathable gas to a patient |
JP4370192B2 (ja) | 2004-03-25 | 2009-11-25 | パナソニック株式会社 | 基板搬送機 |
US20050284469A1 (en) | 2004-06-25 | 2005-12-29 | Tobia Ronald L | Integrated control of ventilator and nebulizer operation |
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2004
- 2004-04-27 US US10/833,932 patent/US8616195B2/en active Active
- 2004-07-06 EP EP04756695.5A patent/EP1646276B1/en not_active Expired - Lifetime
- 2004-07-06 CA CA2532978A patent/CA2532978C/en not_active Expired - Lifetime
- 2004-07-06 JP JP2006521094A patent/JP4970938B2/ja not_active Expired - Lifetime
- 2004-07-06 EP EP20174258.2A patent/EP3718585B1/en not_active Expired - Lifetime
- 2004-07-06 WO PCT/US2004/021628 patent/WO2005009323A2/en active Application Filing
- 2004-07-06 AU AU2004258880A patent/AU2004258880B2/en not_active Expired
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US8616195B2 (en) | 2013-12-31 |
AU2004258880A1 (en) | 2005-02-03 |
US20050011514A1 (en) | 2005-01-20 |
AU2004258880B2 (en) | 2009-12-24 |
WO2005009323A3 (en) | 2005-05-06 |
NO20060378L (no) | 2006-02-17 |
EP3718585A2 (en) | 2020-10-07 |
EP1646276A4 (en) | 2013-05-15 |
CA2532978A1 (en) | 2005-02-03 |
EP3718585B1 (en) | 2022-07-20 |
EP1646276A2 (en) | 2006-04-19 |
WO2005009323A2 (en) | 2005-02-03 |
NO336224B1 (no) | 2015-06-22 |
EP3718585A3 (en) | 2021-01-13 |
EP1646276B1 (en) | 2020-06-03 |
CA2532978C (en) | 2014-05-06 |
JP2006528025A (ja) | 2006-12-14 |
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