JP4789453B2 - アントシアニン吸収促進剤 - Google Patents
アントシアニン吸収促進剤 Download PDFInfo
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- JP4789453B2 JP4789453B2 JP2004348457A JP2004348457A JP4789453B2 JP 4789453 B2 JP4789453 B2 JP 4789453B2 JP 2004348457 A JP2004348457 A JP 2004348457A JP 2004348457 A JP2004348457 A JP 2004348457A JP 4789453 B2 JP4789453 B2 JP 4789453B2
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- JP
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- Prior art keywords
- anthocyanin
- anthocyanins
- phytic acid
- absorption
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Description
即ち、本発明は、フィチン酸を有効成分とするアントシアニン吸収促進剤である。
さらに本発明は、アントシアニンにフィチン酸を添加使用することを特徴とする、アントシアニン吸収促進方法である。
さらに本発明は、アントシアニンとフィチン酸を含有することを特徴とする、アントシアニン吸収促進能を有するアントシアニン含有組成物である。
ブルーベリー濃縮果汁100g(Bx.65,アントシアニン0.9%(濃縮果汁100gあたりアントシアニン0.9g))に、フィチン酸50%水溶液(築野食品工業社製、食品添加物)5gを加えて、アントシアニン吸収促進剤105gを調製した。
アントシアニンとして、カシスポリフェノール20(明治製菓社製)を用いた。これは、カシスより膜濃縮およびエタノール抽出したアントシアニン抽出物であり、アントシアニンを24.1重量%含む粉末である。この粉末1gを20mlの蒸留水へ溶解し、フィチン酸としてそれぞれ表1に示したような量のフィチン酸50%水溶液(築野食品工業社製、食品添加物)を加えてアントシアニン吸収促進能を有する組成物(1−1)〜(1−4)を調製した。
アントシアニンとして、エルダーベリーアントシアニン粉末(iprona社製、rubini、アントシアニン含有率20重量%)とビルベリーアントシアニン粉末(常磐植物化学研究所社製、ビルベロン25、アントシアニン含有率25重量%)を用いた。エルダーベリーアントシアニン粉末1gを20mlの蒸留水へ溶解し、フィチン酸として50%フィチン酸溶液(築野食品工業社製、食品添加物)を0.4g加えてアントシアニン吸収促進能を有する組成物(2)を調製した。また、ビルベリーアントシアニン粉末1gを20mlの蒸留水へ溶解し、フィチン酸として50%フィチン酸溶液(築野食品工業社製、食品添加物)を0.4g加えてアントシアニン吸収促進能を有する組成物(3)を調製した。
本試験ではアントシアニン組成物として、実施例2のアントシアニン吸収促進能を有する組成物(1−1)〜(1−4)を用いた。生後7週齢のウィスター(Wistar)系雄性ラットを、各群6匹ずつを16時間絶食後、上記組成物(1−1)〜(1−4)を単回胃内経口投与した。試験区は実施例2の表1に示したような組成となっている。これらをラットへの投与前、投与4時間後まで、投与4〜6時間後まで、投与8〜24時間後までの尿を採取し、尿中へのアントシアニン***量を既報(Matsumoto et. al.,J.Agric.Food.Chem.49(3),546-1551,2001)に従って分析した。投与前の尿には、アントシアニンは検出されなかった。その結果を図1に示した。この図からフィチン酸の添加量の増加に伴い、アントシアニンの尿中***量が増加し、アントシアニンの吸収量が増加していることが分かる。特に、アントシアニン100mgあたり83mg以上のフィチン酸を添加することにより、吸収量は10倍以上に飛躍的に上昇していることが分かる。また、アントシアニン100mgあたりフィチン酸含有量が41mg以下の群は投与後4時間までが***量が最大であるのに対し、フィチン酸含有量が83mg以上の群では、投与後4〜8時間の群が***量が最大となっており、血中での滞留時間の増加が期待できた。
本試験ではアントシアニン組成物として、実施例3のアントシアニン吸収促進能を有する組成物(2)及び(3)を用いた。
実施例4と同様に、アントシアニン組成物は、アントシアニンとしてカシスポリフェノール20(明治製菓社製)を、フィチン酸はフィチン酸50%水溶液(築野食品工業社製、食品添加物)を用いた。
1)カシスポリフェノール20粉末を水に溶かして飲用した。
2)カシスポリフェノール20粉末を1%フィチン酸水溶液に溶解して飲用した。
比較例として、クエン酸を用いてアントシアニンの吸収促進効果を比較した。
実施例6と同様に、アントシアニンとしてカシスポリフェノール20(明治製菓社製)を用い、クエン酸は和光純薬社製の食品添加物を用いた。
1)カシスポリフェノール20粉末を水に溶かして飲用した。
2)カシスポリフェノール20粉末をクエン酸1.8gを水に溶かし、全体を60gとしたものを飲用した。クエン酸濃度は3%となる。
Claims (2)
- フィチン酸を有効成分とするアントシアニン吸収促進剤。
- アントシアニンが、ブルーベリー、ビルベリー、カシス(ブラックカーラント)、エルダーベリー由来のものである請求項1記載のアントシアニン吸収促進剤。
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Application Number | Priority Date | Filing Date | Title |
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JP2004348457A JP4789453B2 (ja) | 2004-12-01 | 2004-12-01 | アントシアニン吸収促進剤 |
Applications Claiming Priority (1)
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