JP4788994B2 - 機能性飲食品 - Google Patents
機能性飲食品 Download PDFInfo
- Publication number
- JP4788994B2 JP4788994B2 JP2005263779A JP2005263779A JP4788994B2 JP 4788994 B2 JP4788994 B2 JP 4788994B2 JP 2005263779 A JP2005263779 A JP 2005263779A JP 2005263779 A JP2005263779 A JP 2005263779A JP 4788994 B2 JP4788994 B2 JP 4788994B2
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- Prior art keywords
- tea
- extract
- antiallergic
- allergic
- green tea
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Images
Landscapes
- Tea And Coffee (AREA)
- Non-Alcoholic Beverages (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Fruits And Vegetables (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Description
本発明に係る機能性飲食品は、所定の茶葉由来のメチル化カテキン成分を有効成分量含有する。ここで「メチル化カテキン」とは、一般式(1)で示されるものであり、メチル化されたカテキン及び精製の際の不可避成分をいう。本発明におけるメチル化カテキンは主として、エピカテキン−3−O−(3−O−メチル)ガレート(以下、ECG3”Meという)、エピカテキン−3−O−(4−O−メチル)ガレート(以下、ECG4”Meという)、エピガロカテキン−3−O−(4−O−メチル)ガレート(以下、EGCG4”Meという)、ガロカテキン−3−O−(3−O−メチル)ガレート(以下、GCG3”Meという)、カテキン−3−O−(3−O−メチル)ガレート(以下、CG3”Meという)、カテキン−3−O−(4−O−メチル)ガレート(以下、CG4”Meという)、又は、ガロカテキン−3−O−(4−O−メチル)ガレート(以下、GCG4”Meという)、エピガロカテキン−3−O−(3−O−メチル)ガレート(以下、EGCG3”Meとする)及びこれらの異性化体を含むことが好ましい。
マスト細胞からの炎症性サイトカイン産生抑制活性に及ぼす組み合わせ効果について検討した。茶葉抽出液には、2.5gのべにふうき茶葉粉末を25mlの熱水で10分抽出し、濾過した上清を用いた。上清はタンニン含量を酒石酸鉄法で測定し、タンニン含量で細胞1×107個当り50μgとなる量で添加した。野菜抽出液は、それぞれの野菜(ブロッコリスプラウト、かいわれ大根、レッドキャベツスプラウト、ルッコラスプラウト、ショウガ)5gに5mlの50%エタノールを添加して乳鉢でよくすりつぶした。これを3000rpmで15分遠心後、上清を細胞1×107個当り50μlとなる量で添加した。得られた飲料を試験飲料1から5とした。
アレルギー性鼻炎軽症者における「べにふうき」緑茶とショウガエキスの同時摂取試験を行なった。被験者には、医療機関で治療を受けておらず、かつ、スギ花粉症状を有し、スギ特異的IgE値がプラスである27名(年齢23歳から59歳、男性18名(平均年齢40.4歳)、女性9名(平均年齢37.8歳))を選択した。
ショウガエキス添加量による好酸球炎症性タンパク質産生抑制効果の検討を行なった。
ショウガエキス添加量によるマスト細胞ヒスタミン遊離産生抑制効果の検討を行なった。
ショウガエキスによるマスト細胞好酸球遊走因子産生抑制増強効果
本実施例におけるショウガエキスは、しょうがをすりおろして50%エタノールに30分浸漬させ、さらに遠心分離したものを用いた。
Claims (5)
- 抗アレルギー成分であるメチル化カテキンを含有する緑茶若しくは包種茶の抽出物を、抗アレルギー有効成分量含有する抗アレルギー剤であって、
抗アレルギー成分活性物質を含有する野菜抽出物を、少なくとも抗アレルギー成分活性増強量含有し、
前記野菜抽出物は、ショウガの抽出物を含み、
前記アレルギーはアレルギー性鼻炎である抗アレルギー剤。 - 前記緑茶又は包種茶は、べにふうき、べにふじ、べにほまれ、やえほ、するがわせ、ゆたかみどり、かなやみどり、青心大パン、青心烏龍、大葉烏龍、べにひかり、やまかい、やまとみどり、おくみどり、台湾系統種、中国種もしくはこれらの混合物の茶葉である請求項1に記載の抗アレルギー剤。
- 前記緑茶又は包種茶の粉末を、100ml当たり50mgから50g含有する請求項1又は2に記載の抗アレルギー剤。
- 前記緑茶粉末を、1用量当たり1.5g以上含有する請求項1から3いずれかに記載の抗アレルギー剤。
- 抗アレルギー成分活性物質を含有するショウガ抽出物からなる、メチル化カテキンを含有する緑茶若しくは包種茶の抽出物の抗アレルギー性鼻炎活性増強剤。
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JP2008178319A (ja) * | 2007-01-23 | 2008-08-07 | Asahi Soft Drinks Co Ltd | 容器入り茶飲料群の製造方法 |
JP5424533B2 (ja) * | 2007-01-23 | 2014-02-26 | アサヒ飲料株式会社 | 容器入り茶飲料群の製造方法 |
JP2008297209A (ja) * | 2007-05-29 | 2008-12-11 | Yomeishu Seizo Co Ltd | 脂質代謝改善組成物 |
WO2009002298A1 (en) * | 2007-06-22 | 2008-12-31 | Supranaturals, Llc | Antioxidant drink for dietary supplementation |
US20120183614A1 (en) * | 2009-10-06 | 2012-07-19 | Koji Yanae | Polyphenol compound absorption promoter and utilization of same |
JP2012090526A (ja) * | 2010-10-22 | 2012-05-17 | Suntory Holdings Ltd | 生姜エキスの製造方法 |
CN102987473A (zh) * | 2012-07-18 | 2013-03-27 | 徐州康汇百年食品有限公司 | 一种牛蒡黄瓜复合健身饮料 |
JP6105940B2 (ja) * | 2013-01-09 | 2017-03-29 | アサヒ飲料株式会社 | 酸性飲料及び耐熱性好酸性菌の増殖抑制方法 |
JP6778922B2 (ja) * | 2016-01-19 | 2020-11-04 | 敏明 齋藤 | 天然物由来成分含有組成物の製造方法、天然物由来成分含有組成物、これを用いた機能性飲食料品 |
JP2022092966A (ja) * | 2020-12-11 | 2022-06-23 | トヨタ自動車株式会社 | ジペプチジルペプチダーゼiv阻害剤、機能性表示食品 |
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