JP4783014B2 - 血管閉塞を破壊するための超音波カテーテル - Google Patents
血管閉塞を破壊するための超音波カテーテル Download PDFInfo
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- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
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Description
本発明は、一般に医療デバイスおよび方法に関する。詳細には、本発明は、閉塞性血管内障害を治療するための超音波カテーテルデバイスおよび方法に関する。
本発明の超音波カテーテルデバイスおよび方法は、血管の閉塞の強化された破壊を提供する。一般に、超音波カテーテルは、1個以上のルーメンを有する長形の可撓性カテーテル本体を備える。超音波伝達部材またはワイヤは、カテーテル本体のルーメンを通って長軸方向延び、多くの実施形態では、ガイドワイヤの管も、同じルーメンを通って延びる。遠位ヘッドは、超音波伝達部材またはワイヤの遠位端に固定されるか、さもなければ機械的に結合され、カテーテル本体の遠位端に隣接して配置される。カテーテル本体の遠位端は、多くの場合、遠位ヘッドに重畳し、遠位ヘッドは、カテーテル本体の遠位端に直接的には固着されない。したがって、遠位先端は、超音波エネルギーが超音波伝達部材を介して印加される場合、カテーテル本体の遠位端に対して自由に移動し得る(または「浮動する」)。
本発明の超音波カテーテルデバイスおよび方法は、全体として、石灰化閉塞を含む血管内閉塞のアブレーションおよび破壊を行なう。ワイヤなどの超音波エネルギー伝達部材は、一般に、エネルギーを超音波変換器からカテーテルの遠位ヘッドに伝達する。伝達されるエネルギーは遠位ヘッドを振動させ、こうした振動エネルギーは、血管の閉塞をアブレートするために使用される。一般に、超音波カテーテルの遠位ヘッドは、カテーテル本体に直接的には固着されず、その結果、遠位ヘッドはカテーテル本体の遠位端に対して、自由に移動する(つまり、「浮動する」)。こうした移動の自由は、エネルギー伝達効率を増加させ、超音波伝達ワイヤに対する応力を減少させ、その結果、ワイヤの磨耗および引裂並びに永久的な破損を減少させる。さらに、遠位ヘッドに固着されないため、より大きいアブレーション能力を提供することができ、石灰化閉塞を破壊することができる。
Claims (7)
- 血管内の閉塞を破壊するための超音波カテーテルであって、該超音波カテーテルは以下:
近位端、遠位端および少なくとも1個のルーメンを有する長形の可撓性のカテーテル本体;
該カテーテル本体のルーメンを通って長軸方向に延びる超音波伝達部材であって、別個の超音波発生デバイスに接続可能な近位端を有する超音波伝達部材;
該超音波伝達部材の遠位端に結合された遠位ヘッド;ならびに
該カテーテル本体のルーメンの少なくとも一部分を通って長軸方向に延び、前記遠位ヘッドを通って少なくとも部分的に延びるガイドワイヤの管;
を備え、
該遠位ヘッドは、該カテーテル本体の遠位端に隣接して配置されるが該カテーテル本体の遠位端に直接的には固着されないか、または該カテーテル本体の遠位端が、該遠位ヘッドの少なくとも一部分に重なり合うが、該遠位ヘッドに直接的には固着されず、
該ガイドワイヤの管が、該遠位ヘッドに固着され、そして
該ガイドワイヤの管の外壁が、接着点において該カテーテル本体の内壁に固着される、超音波カテーテル。 - 前記遠位ヘッドの一部分の周囲に配置されたポリマースリーブをさらに備え、該ポリマースリーブが、前記遠位ヘッドの側面開口部を通して、前記ガイドワイヤの管と結合する、請求項1に記載の超音波カテーテル。
- 前記ポリマースリーブが、前記遠位ヘッドの側面開口部を通して延びる接着剤を介して、前記ガイドワイヤの管に結合される、請求項2に記載の超音波カテーテル。
- 請求項1〜3のいずれか1項に記載の超音波カテーテルであって、該超音波カテーテルは、前記ルーメン内で、該カテーテル本体と結合する遠位スリーブをさらに備え、該スリーブが、前記超音波伝達部材の一部分を包囲する中空円筒状部材を備える、超音波カテーテル。
- 前記カテーテル本体の前記ルーメン内に配置された固定部材をさらに備え、該固定部材が、前記遠位ヘッドに結合する遠位端および該カテーテル本体に結合する近位端を有する、請求項1〜4のいずれか1項に記載の超音波カテーテル。
- 請求項1〜5のいずれか1項に記載の超音波カテーテルであって、該超音波カテーテルは、前記カテーテル本体の遠位端付近に位置する少なくとも1個の流体出口ポートをさらに備え、該流体出口ポートが、該カテーテル本体の少なくとも1個のルーメンと連通し、該ルーメンの近位端内に注入される流体が、該ルーメンを長軸方向に通過して、少なくとも1個の該流体出口ポートから流出する、超音波カテーテル。
- 請求項1〜6のいずれか1項に記載の超音波カテーテルであって、該超音波カテーテルは、前記カテーテル本体の前記近位端に結合する近位端コネクタアセンブリをさらに備え、該近位端コネクタアセンブリが;
該カテーテル本体の近位端に結合し、中空ボアを有し、該中空ボアが、該カテーテル本体の少なくとも1個のルーメンと連通し、前記超音波伝達部材が、該カテーテル本体から該中空ボアの少なくとも一部分を通って近位に延びる長形剛性本体;
該超音波伝達部材の周囲を囲む中空ボア内に配置され、振動を吸収するための1個以上の吸収部材;および
該近位端コネクタアセンブリの近位端上にある音響コネクタ装置であって、該超音波伝達部材を別個の超音波発生装置に接続し、その結果、超音波エネルギーが、該超音波伝達部材を通って前記遠位ヘッドに伝達される音響コネクタ装置、
を備える、超音波カテーテル。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/229,371 | 2002-08-26 | ||
US10/229,371 US7137963B2 (en) | 2002-08-26 | 2002-08-26 | Ultrasound catheter for disrupting blood vessel obstructions |
PCT/US2003/026976 WO2004018019A2 (en) | 2002-08-26 | 2003-08-26 | Ultrasound catheter for disrupting blood vessel obstructions |
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WO2004018019A3 (en) | 2004-05-27 |
US7955293B2 (en) | 2011-06-07 |
US20070021690A1 (en) | 2007-01-25 |
US7137963B2 (en) | 2006-11-21 |
US20040039311A1 (en) | 2004-02-26 |
AU2003262952A1 (en) | 2004-03-11 |
US20140214064A1 (en) | 2014-07-31 |
JP5178780B2 (ja) | 2013-04-10 |
EP1553996A4 (en) | 2010-12-29 |
US20130072824A1 (en) | 2013-03-21 |
JP2005537051A (ja) | 2005-12-08 |
EP1553996A2 (en) | 2005-07-20 |
US9314258B2 (en) | 2016-04-19 |
AU2003262952A8 (en) | 2004-03-11 |
JP2010221064A (ja) | 2010-10-07 |
US10376272B2 (en) | 2019-08-13 |
EP1553996B1 (en) | 2017-03-15 |
WO2004018019A2 (en) | 2004-03-04 |
US7621902B2 (en) | 2009-11-24 |
US8690819B2 (en) | 2014-04-08 |
US20110237983A1 (en) | 2011-09-29 |
US20170354428A1 (en) | 2017-12-14 |
US20070021691A1 (en) | 2007-01-25 |
US8308677B2 (en) | 2012-11-13 |
US9770250B2 (en) | 2017-09-26 |
US20160242797A1 (en) | 2016-08-25 |
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