JP4621843B2 - 装着体および濃度測定装置 - Google Patents
装着体および濃度測定装置 Download PDFInfo
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- JP4621843B2 JP4621843B2 JP2008291658A JP2008291658A JP4621843B2 JP 4621843 B2 JP4621843 B2 JP 4621843B2 JP 2008291658 A JP2008291658 A JP 2008291658A JP 2008291658 A JP2008291658 A JP 2008291658A JP 4621843 B2 JP4621843 B2 JP 4621843B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- A—HUMAN NECESSITIES
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150022—Source of blood for capillary blood or interstitial fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
- A61B5/150061—Means for enhancing collection
- A61B5/150099—Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
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- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150213—Venting means
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- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150229—Pumps for assisting the blood sampling
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- A—HUMAN NECESSITIES
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- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
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- A61B5/150381—Design of piercing elements
- A61B5/150503—Single-ended needles
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- A—HUMAN NECESSITIES
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- A61B5/15101—Details
- A61B5/15103—Piercing procedure
- A61B5/15107—Piercing being assisted by a triggering mechanism
- A61B5/15113—Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
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- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15101—Details
- A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
- A61B5/15123—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising magnets or solenoids
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- A—HUMAN NECESSITIES
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
- A61B5/15188—Constructional features of reusable driving devices
- A61B5/1519—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for propelling the piercing unit
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
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- A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
- A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
- A61B5/15188—Constructional features of reusable driving devices
- A61B5/15192—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing
- A61B5/15194—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for retracting the lancet unit into the driving device housing fully automatically retracted, i.e. the retraction does not require a deliberate action by the user, e.g. by terminating the contact with the patient's skin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N9/00—Investigating density or specific gravity of materials; Analysing materials by determining density or specific gravity
- G01N9/002—Investigating density or specific gravity of materials; Analysing materials by determining density or specific gravity using variation of the resonant frequency of an element vibrating in contact with the material submitted to analysis
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- B01L2300/0809—Geometry, shape and general structure rectangular shaped
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- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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Description
20の一端部20a、およびカバー3の貫通孔30により構成されている。したがって、液溜部4は、バイオセンサXの厚み方向に貫通した形態を有し、上方および下方に開放したものとされている。液溜部4の内部容積は、たとえば1.5〜2.5μLとされる。
ッチ機構や電磁石を利用した機構により駆動される。各コネクタ66は、図外の電気回路に導通しており、上下方向に往復移動可能なコネクタピン66aを有している。各コネクタピン66aは、血糖値測定装置6に装着体7を装着したときに、バイオセンサXの端子部14b,15bに接触させるためのものである。
B 試料液
S 皮膚
1 基板
2 スペーサ
3 カバー
4 液溜部
5 キャピラリ
6 血糖値測定装置
7 装着体
11 第1貫通孔
12 第2貫通孔
13 密着部材
14 作用極
15 対極
20 スリット
31,32 検知電極
Claims (5)
- 試料液中の特定成分の濃度を測定するための濃度測定装置に装着して使用される装着体であって、試料液を移動させるためのキャピラリを有する測定用具を備えた装着体において、
前記測定用具は、前記キャピラリに連通し、かつ前記キャピラリに導入すべき試料液を保持するための液溜部と、前記液溜部に保持させた試料液を、前記キャピラリ内に導入するか否かを選択するための液導入選択手段と、を備えており、
前記液導入選択手段は、前記キャピラリ内の気体を排出するための排出口を有し、この排出口が開放される状態と閉鎖される状態とを選択することにより、前記キャピラリ内に試料液が導入されるか否かを選択できるように構成されていることを特徴とする、装着体。 - 前記測定用具は、基板と、この基板とともに前記キャピラリを構成するカバーと、を備えている、請求項1に記載の装着体。
- 穿刺針を有する穿刺体をさらに備えており、かつ、
前記液溜部は、前記基板および前記カバーを、それらの厚み方向に一連に貫通した形態とされ、前記穿刺針が挿通できるように構成されている、請求項2に記載の装着体。 - 測定用具を備えた装着体を装着して使用し、かつ試料液中の特定成分の濃度を測定するための濃度測定装置であって、
前記測定用具としては、試料液を移動させるためのキャピラリと、前記キャピラリに連通し、かつ前記キャピラリに導入すべき試料液を保持するための液溜部と、前記液溜部に保持させた試料液を、前記キャピラリ内に導入するか否かを選択するための液導入選択手段と、を備えたものが使用され、かつ、前記キャピラリ内に試料液が導入されるか否かを選択させるための選択手段をさらに備えており、
前記液導入選択手段は、前記キャピラリ内の気体を外部に排出するための排出口を有しており、前記選択手段は、前記排出口を開閉するための開閉部材を有していることを特徴とする、濃度測定装置。 - 前記測定用具としては、目的量の試料液が前記液溜部に供給されたか否かを検知するために利用される検知手段を備えたものが使用され、かつ、
前記検知手段を利用して、目的量の試料液が前記液溜部に供給されたか否かを判断するための判断手段をさらに備えている、請求項4に記載の濃度測定装置。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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JP2008291658A JP4621843B2 (ja) | 2001-09-11 | 2008-11-14 | 装着体および濃度測定装置 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP2001275532 | 2001-09-11 | ||
JP2008291658A JP4621843B2 (ja) | 2001-09-11 | 2008-11-14 | 装着体および濃度測定装置 |
Related Parent Applications (1)
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JP2003529138A Division JP4246629B2 (ja) | 2001-09-11 | 2002-09-06 | 測定用具 |
Publications (2)
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JP2009066425A JP2009066425A (ja) | 2009-04-02 |
JP4621843B2 true JP4621843B2 (ja) | 2011-01-26 |
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JP2003529138A Expired - Fee Related JP4246629B2 (ja) | 2001-09-11 | 2002-09-06 | 測定用具 |
JP2008291658A Expired - Fee Related JP4621843B2 (ja) | 2001-09-11 | 2008-11-14 | 装着体および濃度測定装置 |
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JP2003529138A Expired - Fee Related JP4246629B2 (ja) | 2001-09-11 | 2002-09-06 | 測定用具 |
Country Status (6)
Country | Link |
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US (1) | US7640047B2 (ja) |
EP (1) | EP1426758B1 (ja) |
JP (2) | JP4246629B2 (ja) |
CN (1) | CN1282870C (ja) |
AT (1) | ATE519420T1 (ja) |
WO (1) | WO2003025559A1 (ja) |
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US20030032874A1 (en) | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
US7004928B2 (en) | 2002-02-08 | 2006-02-28 | Rosedale Medical, Inc. | Autonomous, ambulatory analyte monitor or drug delivery device |
US8010174B2 (en) | 2003-08-22 | 2011-08-30 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
US8260393B2 (en) | 2003-07-25 | 2012-09-04 | Dexcom, Inc. | Systems and methods for replacing signal data artifacts in a glucose sensor data stream |
US9247901B2 (en) | 2003-08-22 | 2016-02-02 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
US7052652B2 (en) * | 2003-03-24 | 2006-05-30 | Rosedale Medical, Inc. | Analyte concentration detection devices and methods |
US7074307B2 (en) | 2003-07-25 | 2006-07-11 | Dexcom, Inc. | Electrode systems for electrochemical sensors |
WO2007120442A2 (en) | 2003-07-25 | 2007-10-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US8275437B2 (en) | 2003-08-01 | 2012-09-25 | Dexcom, Inc. | Transcutaneous analyte sensor |
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EP1426758B1 (en) | 2011-08-10 |
EP1426758A4 (en) | 2007-11-28 |
CN1282870C (zh) | 2006-11-01 |
JP2009066425A (ja) | 2009-04-02 |
EP1426758A1 (en) | 2004-06-09 |
WO2003025559A1 (fr) | 2003-03-27 |
JP4246629B2 (ja) | 2009-04-02 |
JPWO2003025559A1 (ja) | 2004-12-24 |
CN1554019A (zh) | 2004-12-08 |
US20040242982A1 (en) | 2004-12-02 |
ATE519420T1 (de) | 2011-08-15 |
US7640047B2 (en) | 2009-12-29 |
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