JP4583146B2 - Sample extraction container and kit - Google Patents

Sample extraction container and kit Download PDF

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JP4583146B2
JP4583146B2 JP2004328700A JP2004328700A JP4583146B2 JP 4583146 B2 JP4583146 B2 JP 4583146B2 JP 2004328700 A JP2004328700 A JP 2004328700A JP 2004328700 A JP2004328700 A JP 2004328700A JP 4583146 B2 JP4583146 B2 JP 4583146B2
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JP2006138748A (en
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靖治 難波
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BL KK
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Description

本発明は、患者の鼻、喉結膜などを綿棒で拭うことで採取した検体を抽出溶媒中に抽出するのに好適な検体抽出用容器及びキットに関し、特に、イムノクロマトグラフィー測定用のテストストリップに展開させるための被験試料を調製するのに好適な検体抽出用容器及びキットに関する。   The present invention relates to a specimen extraction container and kit suitable for extracting a specimen collected by wiping a patient's nose, throat conjunctiva, etc. with a cotton swab into an extraction solvent, and in particular, developed on a test strip for immunochromatography measurement. The present invention relates to a specimen extraction container and kit suitable for preparing a test sample to be prepared.

イムノクロマトグラフィー測定用の被験試料は、被疑患者の涙、目脂、喀痰、唾液、大便などの生体試料や患部を清拭したガーゼ、綿棒などを、予め試験用チューブなどの容器に入れておいた抽出溶剤に浸漬して検体を分散又は溶解して抽出液として調製される。そして、測定は、この抽出液をピペットなどで吸い上げてから、イムノクロマトグラフィー測定用のテストストリップの試料注入部に注入してテストストリップに展開させることにより行われる。   Test samples for immunochromatography were preliminarily placed in a container such as a test tube with biological samples such as tears, eyelids, sputum, saliva, stool, gauze, cotton swabs, etc. A specimen is dispersed or dissolved by immersion in an extraction solvent to prepare an extract. The measurement is performed by sucking up this extract with a pipette or the like, and then injecting the extract into a sample injection portion of a test strip for immunochromatography measurement so as to develop the test strip.

特開2003-344406号公報JP 2003-344406 A 特開2004-271341号公報JP 2004-271341 A

しかし、例えば、アデノウイルスのような感染力の強い微生物が検体となる場合、上記したような被験試料の調製方法では、使用済みの綿棒や抽出液の廃棄の管理を適正に行わないと、院内感染などの問題を生じさせる危険性がある。   However, for example, when a highly infectious microorganism such as adenovirus is used as a specimen, the method for preparing a test sample as described above requires proper management of the disposal of used swabs and extracts. There is a risk of causing problems such as infection.

そこで、本発明は、綿棒で拭うことで採取した検体を抽出溶媒中に簡便な操作で抽出することができ、かつ、使用後も安全に廃棄することのできる検体抽出用容器及びキットを提供することを目的とする。   Therefore, the present invention provides a sample extraction container and kit that can extract a sample collected by wiping with a cotton swab into an extraction solvent by a simple operation and can be safely discarded after use. For the purpose.

本発明によれば、開口端とそれに対向する閉止端とを備えたチューブ状の本体と、該本体の開口端に着脱可能に取り付けられる第一の蓋体と、該第一の蓋体と交換して前記本体の開口端に着脱自在に取り付けられるノズルと、該ノズルに着脱自在に取り付けられる第二の蓋体とからなり、前記本体は綿棒を収容するに十分な内のり寸法を備えていることを特徴とする検体抽出用容器が提供される。   According to the present invention, a tubular main body having an open end and a closed end opposite to the open end, a first lid attached to the open end of the main body so as to be detachable, and replacement with the first lid And a nozzle that is detachably attached to the opening end of the main body and a second lid that is detachably attached to the nozzle, and the main body has an inner dimension sufficient to accommodate a cotton swab. A specimen extraction container is provided.

さらに、本発明によれば、前記検体抽出用容器と、該容器の本体に収容された抽出溶媒と、予め滅菌された綿棒とを備えてなる検体抽出用キットが提供される。   Furthermore, according to the present invention, there is provided a sample extraction kit comprising the sample extraction container, an extraction solvent accommodated in the main body of the container, and a cotton swab sterilized in advance.

本発明の検体抽出用容器及びキットによれば、予め本体に抽出溶媒を入れておき、生体試料や患部を清拭した綿棒を本体に入れて、第二の蓋体が取り付けられたノズルを本体の開口端に取り付け、容器を手で振とうすることによって、容器内の綿棒と抽出溶媒とを混合して抽出液を調製した後、第二の蓋体を取り外し、ノズルを下方に向けて抽出液をノズルから注ぎ出すことにより被験試料を得ることができる。特に、イムノクロマトグラフィー測定の場合、抽出液をノズルから直接テストストリップの試料注入部に注入することができ好都合である。また、使用済みの綿棒や抽出液は、容器内部に収容された状態でそのまま廃棄できるので、廃棄物の安全な管理が行える。   According to the sample extraction container and kit of the present invention, the extraction solvent is put in the main body in advance, a biological sample and a swab from which the affected area is wiped are put in the main body, and the nozzle to which the second lid is attached is installed in the main body. Prepare the extract by mixing the cotton swab and the extraction solvent in the container by shaking the container by hand, and then remove the second lid and extract the nozzle downward A test sample can be obtained by pouring the liquid from the nozzle. In particular, in the case of immunochromatographic measurement, the extract can be conveniently injected directly from the nozzle into the sample injection part of the test strip. Moreover, since the used cotton swab and the extract liquid can be discarded as they are in the container, the waste can be managed safely.

以下、本発明を図示の具体例に基づいて説明するが、本発明は該具体例のみに限定されるものではない。   Hereinafter, although the present invention will be described based on the illustrated specific examples, the present invention is not limited to the specific examples.

図１には、本具体例に係る容器の本体１の構成が示されている。図１（ｂ）から明らかなように、本体１は、チューブ状の形状を備え、その一端は開口端１１とされ、他端は閉止端１２とされている。図１（ｃ）から明らかなように、本体１の開口端１１に隣接する側壁部分１４は断面が円形の形状であるのに対し、本体１の閉止端１２に隣接する側壁部分１３は断面が楕円形の形状に形成されている。さらに詳しくは、この断面楕円形の側壁部分１３の断面の長径は、断面円形の側壁部分１４の直径よりも小さくされている。したがって、図１（ｂ）及び図１（ｄ）から明らかなように、本体１は、開口端１１から閉止端１２にかけて、全体的に先細りになるように形成されており、特に、図１（ｄ）から明らかなように、閉止端１２に近づくにつれて扁平な形状になるように形成されている。本体１は、外から中を透視できるように、透明または半透明とすることが好ましい。   FIG. 1 shows the configuration of a container body 1 according to this example. As is clear from FIG. 1B, the main body 1 has a tubular shape, one end of which is an open end 11 and the other end is a closed end 12. As is apparent from FIG. 1C, the side wall portion 14 adjacent to the open end 11 of the main body 1 has a circular cross section, whereas the side wall portion 13 adjacent to the closed end 12 of the main body 1 has a cross section. It is formed in an oval shape. More specifically, the major axis of the cross section of the side wall portion 13 having an elliptical cross section is smaller than the diameter of the side wall portion 14 having a circular cross section. Therefore, as is apparent from FIGS. 1B and 1D, the main body 1 is formed so as to be entirely tapered from the open end 11 to the closed end 12, and in particular, FIG. As is apparent from d), the flat shape is formed as the closed end 12 is approached. The main body 1 is preferably transparent or translucent so that the inside can be seen through from the outside.

図１（ｂ）及び図１（ｄ）から明らかなように、本体１の開口端１１付近の側壁にはねじ切り部１５が設けられて、ここに後述する第一の蓋体２又はノズル３の何れか一つを着脱自在に装着できるようにしている。   As is clear from FIGS. 1B and 1D, a threaded portion 15 is provided on the side wall near the opening end 11 of the main body 1, and the first lid 2 or nozzle 3 described later is provided here. Any one can be detachably mounted.

本発明によれば、本体１の内のり寸法は、使用する綿棒の全体を収容し得る寸法に形成される。本体１は、一般に、使用する抽出溶剤に対して耐性のあるプラスチック材料を用いて射出成形、ブロー成形などの公知の成形方法で成形することによって作成することができる。プラスチック材料としては、例えば、ポリエチレン、ポリプロピレンなどが挙げられるが、ポリエチレンを用いることが好ましい。   According to the present invention, the inner dimension of the main body 1 is formed to a dimension that can accommodate the entire swab to be used. The main body 1 can be generally produced by molding by a known molding method such as injection molding or blow molding using a plastic material resistant to the extraction solvent to be used. Examples of the plastic material include polyethylene, polypropylene, and the like, but it is preferable to use polyethylene.

本発明においては、本体１の閉止端１２に隣接する側壁部分１３は、本体１の開口端１１に隣接する側壁部分よりも柔軟に形成することが好ましい。具体的には、側壁部分１３は手で押して形状を変形させることができるが、手を離した場合、元の形状に復帰する程度の柔軟性を備えることが好ましい。このために、例えば、ねじ切り部１５から僅かに閉止端１２寄りに位置する側壁部分１４の箇所に、本体１の長手方向軸線と直交する方向に張り出した環状の鍔体１４１を本体１と一体に設けることができる。この場合、鍔体１４１によって側壁部分１４が補強されるのに対し、閉止端１２に隣接する側壁部分１３は補強されないため側壁部分１４よりも柔軟な状態になる。別法として、閉止端１２に隣接する側壁部分１３の肉厚を、それよりも開口端１１側に位置する側壁部分１４の肉厚よりも薄くしてもよい。このように構成することにより、抽出液をノズル３から滴下する際に使用者は側壁部分１３を指で容易に押圧することができ、迅速に抽出液をノズル３から排出させることができるようになり好都合である。   In the present invention, the side wall portion 13 adjacent to the closed end 12 of the main body 1 is preferably formed more flexibly than the side wall portion adjacent to the open end 11 of the main body 1. Specifically, the shape of the side wall portion 13 can be changed by being pushed by hand, but it is preferable that the side wall portion 13 has flexibility enough to return to the original shape when the hand is released. For this purpose, for example, an annular housing 141 projecting in a direction perpendicular to the longitudinal axis of the main body 1 is integrally formed with the main body 1 at a location of the side wall portion 14 located slightly closer to the closed end 12 from the threaded portion 15. Can be provided. In this case, the side wall portion 14 is reinforced by the casing 141, whereas the side wall portion 13 adjacent to the closed end 12 is not reinforced, so that the side wall portion 14 becomes more flexible than the side wall portion 14. Alternatively, the thickness of the side wall portion 13 adjacent to the closed end 12 may be made thinner than the thickness of the side wall portion 14 located on the opening end 11 side. By comprising in this way, when dripping an extract from the nozzle 3, a user can press the side wall part 13 easily with a finger so that an extract can be quickly discharged from the nozzle 3. It is convenient.

図２に示されるように、図１の容器は、本体１の開口端１１に着脱可能に取り付けられる部品として、第一の蓋体２とノズル３を備えている。第一の蓋体２は、一端が閉止され他端が開口された円筒部２１を備え、該円筒部２１の開口縁には、該円筒部２１の軸線方向に直交して外方に張り出した環状の鍔部２２を備えている。該円筒部２１の内周面には、本体１のねじ切り部１５と螺合する雌ねじ部（図示せず）が設けられている。したがって、第一の蓋体２は、本体１のねじ切り部１５に螺合させることにより、本体１の開口端１１を着脱可能に閉止して、容器を密閉することができる。この時、第一の蓋体２の鍔部２２と本体１の鍔体１４１が相互に密着するようにすると、容器の密閉性が高められる。また、第一の蓋体２の密閉性能を高めるために、円筒部２１の閉止端の内面にシール材を取り付けてもよい。また、円筒部２１の外周面をローレット加工することにより、第一の蓋体２の着脱を容易にすることができる。   As shown in FIG. 2, the container of FIG. 1 includes a first lid 2 and a nozzle 3 as components that are detachably attached to the open end 11 of the main body 1. The first lid 2 includes a cylindrical portion 21 that is closed at one end and opened at the other end. The opening edge of the cylindrical portion 21 projects outwardly perpendicular to the axial direction of the cylindrical portion 21. An annular collar 22 is provided. On the inner peripheral surface of the cylindrical portion 21, a female screw portion (not shown) that is screwed with the threaded portion 15 of the main body 1 is provided. Therefore, the 1st cover body 2 can detachably close the opening end 11 of the main body 1, and can seal a container by screwing in the threading part 15 of the main body 1. FIG. At this time, if the flange 22 of the first lid 2 and the casing 141 of the main body 1 are in close contact with each other, the sealing performance of the container is improved. In order to improve the sealing performance of the first lid body 2, a sealing material may be attached to the inner surface of the closed end of the cylindrical portion 21. Further, the first lid 2 can be easily attached and detached by knurling the outer peripheral surface of the cylindrical portion 21.

ノズル３は、図示の例では、第一の蓋体２の円筒部２１よりも長さの短い円筒部３１を備え、その一端には第一の蓋体２の鍔部２２と同様の鍔部３２を備え、他端には該円筒部３１よりも小径で先細りのノズル部３３が突出している。円筒部３１の内周面には、本体１のねじ切り部１５と螺合する雌ねじ部３４が形成されている。円筒部３１の外周面にはローレット加工が施されており、ノズル３の着脱を容易にしている。鍔部３２は、本体１に取り付けたとき、本体１の鍔体１４１と密着するようにすることが好ましい。また、円筒部３１の内部にパッキンやシール材を設けて本体１の開口端１１との密着性を高めることもできる。そして、ノズル部３３の外周面には、円筒部３１に隣接する領域にねじ切り部３５を備えている。このノズル３には、そのノズル部３３を閉止するための第二の蓋体４を着脱可能に取り付けることができる。図示の例では、第二の蓋体４は、一端が閉止され他端が開口した略円錐台の形状を備え、その内周面にノズル３のねじ切り部３５に螺合可能な雌ねじ部４１を備えている。第二の蓋体４の外周面には、その軸線方向に伸びる凸条が設けられており、使用者が容易に第二の蓋体４を着脱できるようにしている。   In the illustrated example, the nozzle 3 includes a cylindrical portion 31 that is shorter than the cylindrical portion 21 of the first lid 2, and has a flange similar to the flange 22 of the first lid 2 at one end thereof. 32, and a nozzle portion 33 having a diameter smaller than that of the cylindrical portion 31 projects from the other end. On the inner peripheral surface of the cylindrical portion 31, a female screw portion 34 that is screwed with the threaded portion 15 of the main body 1 is formed. The outer peripheral surface of the cylindrical portion 31 is knurled so that the nozzle 3 can be easily attached and detached. When the collar part 32 is attached to the main body 1, it is preferable that the collar part 32 is in close contact with the casing 141 of the main body 1. Further, it is possible to improve the adhesion with the opening end 11 of the main body 1 by providing a packing or a sealing material inside the cylindrical portion 31. The outer peripheral surface of the nozzle portion 33 is provided with a threaded portion 35 in a region adjacent to the cylindrical portion 31. A second lid 4 for closing the nozzle portion 33 can be detachably attached to the nozzle 3. In the illustrated example, the second lid body 4 has a substantially truncated cone shape with one end closed and the other end opened, and an internal thread portion 41 that can be screwed into the threaded portion 35 of the nozzle 3 on the inner peripheral surface thereof. I have. The outer peripheral surface of the second lid 4 is provided with a ridge extending in the axial direction thereof so that the user can easily attach and detach the second lid 4.

第一の蓋体２、ノズル３および第二の蓋体４のそれぞれは、容器の本体１と同様に、プラスチック材料を用いて射出成形、ブロー成形などの公知の成形方法で成形することによって作成することができる。プラスチック材料としては、例えば、ポリエチレン、ポリプロピレンなどが挙げられるが、容器の本体１よりは硬質の材料を用いて、容易に変形しないように形成することが好ましく、特にポリプロピレンを用いることが好ましい。   Each of the first lid 2, the nozzle 3 and the second lid 4 is formed by molding with a known molding method such as injection molding or blow molding using a plastic material in the same manner as the main body 1 of the container. can do. Examples of the plastic material include polyethylene and polypropylene, but it is preferable to use a material harder than the main body 1 of the container so as not to be easily deformed, and it is particularly preferable to use polypropylene.

また、図示の例では、第一の蓋体１と本体１とは螺合によって結合する形式とされているが、着脱可能に取り付けることができる限り、スナップ式に嵌合する形式などの各種の方法を採用することができる。同様に、ノズル３と本体１との結合形式、および、ノズル３と第二の蓋体の結合形式も、着脱可能に取り付けることができる限り、スナップ式に嵌合する形式などの各種の方法を採用することができる。   In the illustrated example, the first lid 1 and the main body 1 are coupled with each other by screwing. However, as long as the first lid 1 and the main body 1 can be detachably attached, various types such as a snap-fitting type can be used. The method can be adopted. Similarly, the nozzle 3 and the main body 1 and the nozzle 3 and the second lid may be combined in various ways such as a snap-fit manner as long as the nozzle 3 and the second lid can be detachably attached. Can be adopted.

以下、図示の具体例の使用方法を説明する。   Hereinafter, a method of using the illustrated example will be described.

図２を参照すると、通常、容器の本体１には、抽出溶媒を必要量だけ入れた状態で、第一の蓋体２を本体１に取り付けて密閉した状態で保存しておく。その後、綿棒５で生体試料や患部を清拭した後、第一の蓋体２を本体１から取り外し、本体１の開口端１１から綿棒５を本体１に入れ、ノズル３を、第二の蓋体４を取り付けてノズル部３３を閉止した状態で本体１に取り付ける。   Referring to FIG. 2, the container body 1 is usually stored in a sealed state with the first lid 2 attached to the body 1 with a required amount of extraction solvent. Thereafter, after the biological sample and the affected part were wiped off with a cotton swab 5, the first lid 2 was removed from the main body 1, the cotton swab 5 was inserted into the main body 1 from the open end 11 of the main body 1, and the nozzle 3 was connected to the second lid. The body 4 is attached and attached to the main body 1 with the nozzle portion 33 closed.

かくして、図３に示されるように第二の蓋体４で密閉された状態の容器を手で振とうすることにより、綿棒の綿に付着した検体を抽出溶媒に溶解又は分散させる。その後、第二の蓋体４のみを取り外し、ノズル３を下方に向けることによって、検体の抽出液のみを検査のために取り出すことができる。その際、本体１の側壁を手で押圧すると、迅速に抽出液を容器から排出させることができる。その場合、上述のように、側壁部分１３を柔軟に形成しておくと、使用者が手で側壁部分１３を容易に押圧することができ、簡単に抽出液を排出させることができるので好ましい。使用済みの綿棒及び抽出液は、何れも、容器内に収容されているので、検体が感染性のものである場合でも、周囲を汚染する危険性が少なく、ノズル３を第二の蓋体４で密閉した状態で容器ごと廃棄することができ、取り扱いが容易である。   Thus, as shown in FIG. 3, the sample attached to the cotton swab is dissolved or dispersed in the extraction solvent by shaking the container sealed with the second lid 4 by hand. Thereafter, by removing only the second lid 4 and directing the nozzle 3 downward, only the specimen extract can be taken out for examination. At that time, when the side wall of the main body 1 is pressed by hand, the extract can be quickly discharged from the container. In this case, it is preferable that the side wall portion 13 is formed flexibly as described above, because the user can easily press the side wall portion 13 by hand and the extract can be easily discharged. Since the used cotton swab and the extract are both contained in the container, even when the specimen is infectious, there is little risk of contaminating the surroundings, and the nozzle 3 is attached to the second lid 4. The container can be discarded in a hermetically sealed state and is easy to handle.

本発明の容器は、予め本体１に抽出溶媒を収容して第一の蓋体２で密閉した状態で、第二の蓋体４を取り付けたノズル３、滅菌済みの綿棒５とともに検体抽出用キットの形態で提供すると好都合である。この検体抽出用キットは、検体を展開溶媒に抽出して被験試料を作成することが要求されるイムノクロマトグラフィー測定に好都合であり、必要に応じて、イムノクロマトグラフィー測定用テストストリップをも含むキットの形態としてもよい。   The container of the present invention is a specimen extraction kit together with a nozzle 3 attached with a second lid 4 and a sterilized cotton swab 5 in a state in which an extraction solvent is previously stored in a main body 1 and sealed with a first lid 2. It is convenient to provide it in the form of This sample extraction kit is convenient for immunochromatography measurement, which requires extraction of a sample into a developing solvent to prepare a test sample, and optionally includes a test strip for immunochromatography measurement. It is good.

イムノクロマトグラフィーに使用する抽出溶媒としては、ｐＨが４〜１０の緩衝液などが挙げられ、例えば、生理食塩水、りん酸緩衝液、トリス緩衝液、ＨＥＰＥＳ（２−ヒドロキシピペラジン−Ｎ’−２−エタンスルホン酸）緩衝液などから選択できるが、生理食塩水、りん酸緩衝液およびトリス緩衝液が好ましい。緩衝液は、展開溶媒としての性能を高めるために、特開2003-344406号公報に記載のような添加剤、すなわち、ホスホリルコリン基を含有するエチレン系不飽和単量体を構成単位として含有する重合体などの助剤を含有していてもよい。   Examples of the extraction solvent used for immunochromatography include a buffer solution having a pH of 4 to 10, and examples thereof include physiological saline, phosphate buffer, Tris buffer, HEPES (2-hydroxypiperazine-N'-2- Ethane sulfonic acid) buffer, etc., but physiological saline, phosphate buffer and Tris buffer are preferred. In order to enhance the performance as a developing solvent, the buffer solution is an additive as described in JP-A-2003-344406, that is, a heavy polymer containing an ethylenically unsaturated monomer containing a phosphorylcholine group as a constituent unit. An auxiliary agent such as coalescence may be contained.

本発明は、綿棒で拭うことで採取した検体を抽出溶媒中に抽出するのに用いることができ、特に、イムノクロマトグラフィー測定用のテストストリップに展開させるための被験試料を調製するのに有用である。   The present invention can be used to extract a sample collected by wiping with a cotton swab into an extraction solvent, and is particularly useful for preparing a test sample to be developed on a test strip for immunochromatography measurement. .

本発明の検体抽出用容器のチューブ状の本体を示し、（ａ）は平面図、（ｂ）は正面図、（ｃ）は底面図、（ｄ）は側面図である。The tubular main body of the sample extraction container of the present invention is shown, (a) is a plan view, (b) is a front view, (c) is a bottom view, and (d) is a side view. 本発明の検体抽出用容器の構成を示す分解側面図であり、一部断面図で示してある。It is a decomposition side view showing the composition of the sample extraction container of the present invention, and a partial sectional view is shown. 本発明の検体抽出用容器を検体の抽出状態で側面図である。FIG. 3 is a side view of the specimen extraction container of the present invention in a specimen extraction state.

符号の説明Explanation of symbols

１…本体、１１…開口端、１２…閉止端、１３，１４…側壁部分、１５…ねじ切り部、１６…抽出溶媒、１４１…鍔体、２…第一の蓋体、３…ノズル、４…第二の蓋体、５…綿棒。

DESCRIPTION OF SYMBOLS 1 ... Main body, 11 ... Open end, 12 ... Closed end, 13, 14 ... Side wall part, 15 ... Threaded part, 16 ... Extraction solvent, 141 ... Housing, 2 ... First cover body, 3 ... Nozzle, 4 ... Second lid, 5 ... cotton swab.

Claims (6)

開口端（１１）とそれに対向する閉止端（１２）とを備えたチューブ状の本体（１）と、該本体（１）の開口端（１１）に着脱可能に取り付けられる第一の蓋体（２）と、該第一の蓋体（２）と交換して前記本体（１）の開口端（１１）に着脱自在に取り付けられるノズル（３）と、該ノズル（３）に着脱自在に取り付けられる第二の蓋体（４）とからなり、前記本体（１）は綿棒（５）を収容するに十分な内のり寸法を備え、前記本体（１）の前記開口端（１１）に隣接する側壁部分（１４）は断面形状が略円形であり、前記本体（１）の前記閉止端（１２）に隣接する側壁部分（１３）は断面形状が略楕円形状であることを特徴とする検体抽出用容器。 A tube-shaped main body (1) having an open end (11) and a closed end (12) opposite to the open end (11), and a first lid (removably attached to the open end (11) of the main body (1)) 2), a nozzle (3) that is exchanged with the first lid (2) and is detachably attached to the open end (11) of the main body (1), and is detachably attached to the nozzle (3). A side wall adjacent to the open end (11) of the body (1), the body (1) having an inner dimension sufficient to accommodate a cotton swab (5). The portion (14) has a substantially circular cross section, and the side wall portion (13) adjacent to the closed end (12) of the main body (1) has a substantially elliptical cross section . container. 前記本体（１）の前記閉止端（１２）に隣接する側壁部分（１３）は、前記本体（１）の前記開口端（１１）に隣接する側壁部分（１４）よりも柔軟にされている請求項１に記載の容器。 The side wall portion (13) adjacent to the closed end (12) of the main body (1) is more flexible than the side wall portion (14) adjacent to the open end (11) of the main body (1). Item 4. The container according to Item 1. 前記本体（１）の前記開口端（１１）に隣接する側壁部分（１４）には、外方に張り出した環状の鍔体が設けられている請求項２に記載の容器。 The container according to claim 2, wherein a side wall portion (14) adjacent to the open end (11) of the main body (1) is provided with an annular casing projecting outward. 前記本体（１）の前記閉止端（１２）に隣接する側壁部分（１３）の肉厚は、それよりも前記開口端（１１）側の側壁部分（１４）の肉厚よりも薄くされている請求項２又は３に記載の容器。 The thickness of the side wall portion (13) adjacent to the closed end (12) of the main body (1) is made thinner than the thickness of the side wall portion (14) on the opening end (11) side. The container according to claim 2 or 3. 請求項１乃至４の何れか１項に記載の容器と、該容器の本体（１）に収容された抽出溶媒（１６）と、予め滅菌された綿棒（５）とを備えてなる検体抽出用キット。 Sample extraction comprising the container according to any one of claims 1 to 4 , an extraction solvent (16) accommodated in a main body (1) of the container, and a cotton swab (5) sterilized in advance. kit. 前記本体（１）は、第一の蓋体（２）を開口端（１１）に取り付けることで抽出溶媒（１６）を収容した状態で閉止されている請求項５に記載のキット。 The kit according to claim 5 , wherein the body (1) is closed in a state in which the extraction solvent (16) is accommodated by attaching the first lid (2) to the open end (11).
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USD1021132S1 (en) 2021-01-22 2024-04-02 Leadway (Hk) Limited Sample collection bottle

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CA2684998A1 (en) * 2007-04-30 2009-01-29 Nanogen, Inc. Multianalyte assay
JP6660280B2 (en) * 2016-11-29 2020-03-11 株式会社 資生堂 Stratum corneum sampling tool and stratum corneum sampling detection kit
JP7029481B2 (en) * 2020-02-07 2022-03-03 株式会社 資生堂 Weapon layer sampling detection kit
CA3194683A1 (en) * 2020-10-09 2022-04-14 Mingfu Ling Specimen transport medium tube

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JPS6173054A (en) * 1984-09-17 1986-04-15 メデイカル　テクノロジ−　コ−ポレ−シヨン Small bottle for adjusting sample
JPS6244235U (en) * 1985-09-04 1987-03-17
JPH01152236A (en) * 1987-12-10 1989-06-14 Furukawa Alum Co Ltd Al alloy for connector
JPH0350685U (en) * 1989-09-21 1991-05-16
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JPS584200U (en) * 1981-07-02 1983-01-11 小野薬品工業株式会社 Sample collection container set for cotton swabs
JPS6173054A (en) * 1984-09-17 1986-04-15 メデイカル　テクノロジ−　コ−ポレ−シヨン Small bottle for adjusting sample
JPS6244235U (en) * 1985-09-04 1987-03-17
JPH01152236A (en) * 1987-12-10 1989-06-14 Furukawa Alum Co Ltd Al alloy for connector
JPH0350685U (en) * 1989-09-21 1991-05-16
JP2003344232A (en) * 2002-03-18 2003-12-03 Elmex Ltd Wipe inspection kit, and wipe inspection method using the same
WO2004031734A1 (en) * 2002-10-03 2004-04-15 The Secretary Of State For Defence Sampling apparatus

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD1021132S1 (en) 2021-01-22 2024-04-02 Leadway (Hk) Limited Sample collection bottle

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