JP4460451B2 - 回転マイクロ剥離面による物質送達 - Google Patents
回転マイクロ剥離面による物質送達 Download PDFInfo
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Description
Claims (7)
- 回転するように適合された少なくとも1つのハウジング要素を含むハウジングと、
回転させたときに被検者の皮膚を破壊するように適合された少なくとも1つの微小突起アレイと、
対象の角質層を破壊し、前記角質層を貫通することなく前記対象の前記角質層に実質的に侵入するのに十分な力で、前記少なくとも1つの微小突起アレイを前記対象の皮膚に対して機械的に回転させるための機械式回転手段と、
前記少なくとも1つの微小突起アレイの前記機械的回転の前に、前記ハウジング内かつ前記ハウジングの前面から後退した位置に前記少なくとも1つの微小突起アレイを格納するための手段と、
を備え、前記少なくとも1つの微小突起アレイが機械的に回転している時に前記少なくとも1つの微小突起アレイが前記ハウジングの前面に向けて前方に移動することを特徴とする回転式剥離装置。 - 前記対象の皮膚の送達部位に、前記送達部位での前記アレイの前記機械的回転の前に、または前記送達部位での前記アレイの前記機械的回転と同時に、物質を供給するように適合された少なくとも1つの物質送達口をさらに含むことを特徴とする請求項1に記載の回転式剥離装置。
- 前記ハウジングは前記回転するように適合された少なくとも1つのハウジング要素が回転している時に静止状態にある少なくとも1つの静止要素をさらに含むことを特徴とする請求項2に記載の回転式剥離装置。
- 回転するように適合された前記少なくとも1つのハウジング要素はさらに、手動で回転するように適合されていることを特徴とする請求項3に記載の回転式剥離装置。
- 前記剥離装置ハウジングの中に配置され、前記回転するように適合された少なくとも1つのハウジング要素の回転を作動させるために非活動化されるまで、前記マイクロ剥離装置アレイを静止したままに保持するインタロック機構をさらに含むことを特徴とする請求項1に記載の回転式剥離装置。
- 前記インタロック機構は、
縦方向に移動可能な棒に結合され、前記剥離装置ハウジングから突き出たボタンと、
前記剥離装置ハウジングの中にあって、前記縦方向に移動可能な棒を取り囲むばねと
を含み、
前記マイクロ剥離装置アレイは、前記ボタンが押され、それによって前記回転するように適合された少なくとも1つのハウジング要素の回転を作動させるように前記インタロック機構が非活動化されるまで、前記ばねが前記マイクロ剥離装置アレイを静止したままに保持するように、前記縦方向に移動可能な棒の端部に結合されていることを特徴とする請求項5に記載の回転式剥離装置。 - 前記剥離装置ハウジングの中に取り付けられた自由に回転可能なスリーブをさらに含み、前記スリーブは、前記マイクロ剥離装置アレイが取り付けられた端面を有し、且つ前記縦方向に移動可能な棒の前記端部が接続するねじを有し、そのため、前記ボタンに加えられた力によって、前記縦方向に移動可能な棒が前記スリーブの前記ねじに沿って移動し、それによって前記マイクロ剥離装置アレイが回転することを特徴とする請求項6に記載の回転式剥離装置。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40669402P | 2002-08-29 | 2002-08-29 | |
PCT/US2003/026813 WO2004019777A2 (en) | 2002-08-29 | 2003-08-27 | Substance delivery via rotating mocroabrading surface |
Publications (3)
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JP2004531547A Pending JP2005537057A (ja) | 2002-08-29 | 2003-08-27 | 微小突起物アレイ及びそれを用いて物質を組織内に送達する方法 |
JP2004531548A Expired - Fee Related JP4460451B2 (ja) | 2002-08-29 | 2003-08-27 | 回転マイクロ剥離面による物質送達 |
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EP (4) | EP3075410B1 (ja) |
JP (3) | JP4429907B2 (ja) |
AU (3) | AU2003268205B2 (ja) |
CA (3) | CA2497103C (ja) |
ES (4) | ES2599304T3 (ja) |
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2003
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- 2003-08-27 JP JP2004531546A patent/JP4429907B2/ja not_active Expired - Fee Related
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- 2003-08-27 US US10/649,134 patent/US7166086B2/en not_active Expired - Lifetime
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- 2003-08-27 ES ES16169887.3T patent/ES2657432T3/es not_active Expired - Lifetime
- 2003-08-27 CA CA2497128A patent/CA2497128C/en not_active Expired - Fee Related
- 2003-08-27 EP EP03751906.3A patent/EP1531721B1/en not_active Expired - Lifetime
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2007
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