JP4223548B2 - 補足または非補足組織シーラント、それらの製法および使用 - Google Patents
補足または非補足組織シーラント、それらの製法および使用 Download PDFInfo
- Publication number
- JP4223548B2 JP4223548B2 JP51775396A JP51775396A JP4223548B2 JP 4223548 B2 JP4223548 B2 JP 4223548B2 JP 51775396 A JP51775396 A JP 51775396A JP 51775396 A JP51775396 A JP 51775396A JP 4223548 B2 JP4223548 B2 JP 4223548B2
- Authority
- JP
- Japan
- Prior art keywords
- fibrin
- wound
- growth factor
- fibrin sealant
- thrombin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/363—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0015—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0036—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/106—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
- A61L2300/608—Coatings having two or more layers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35100694A | 1994-12-07 | 1994-12-07 | |
US08/351,006 | 1994-12-07 | ||
PCT/US1995/015876 WO1996017633A1 (fr) | 1994-12-07 | 1995-12-06 | Colles tissulaires adjuventees et non adjuventees, procedes de production et d'utilisation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH10510183A JPH10510183A (ja) | 1998-10-06 |
JP4223548B2 true JP4223548B2 (ja) | 2009-02-12 |
Family
ID=23379191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51775396A Expired - Lifetime JP4223548B2 (ja) | 1994-12-07 | 1995-12-06 | 補足または非補足組織シーラント、それらの製法および使用 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0796115A1 (fr) |
JP (1) | JP4223548B2 (fr) |
AU (1) | AU717906B2 (fr) |
CA (1) | CA2207289C (fr) |
WO (1) | WO1996017633A1 (fr) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6117425A (en) | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US6197325B1 (en) | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US7189410B1 (en) | 1990-11-27 | 2007-03-13 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
WO1996040174A1 (fr) * | 1995-06-07 | 1996-12-19 | The American National Red Cross | Produits d'obturation tissulaires completes et non completes, leurs procedes de production et d'utilisation |
EP0993311B1 (fr) * | 1997-06-18 | 2012-11-14 | Angiotech Pharmaceuticals (US), Inc. | Compositions contenant de la thrombine et du collagene microfibrillaire; procede de preparation et d'utilisation de ces compositions |
AT407117B (de) | 1997-09-19 | 2000-12-27 | Immuno Ag | Fibrinschwamm |
US6503527B1 (en) * | 1997-11-17 | 2003-01-07 | Haemacure Corporation | Fibrin sealants or adhesives comprising a hyaluronic acid derivative material |
US6056970A (en) * | 1998-05-07 | 2000-05-02 | Genzyme Corporation | Compositions comprising hemostatic compounds and bioabsorbable polymers |
US7241730B2 (en) | 1998-08-27 | 2007-07-10 | Universitat Zurich | Enzyme-mediated modification of fibrin for tissue engineering: fibrin formulations with peptides |
US7601685B2 (en) | 1998-08-27 | 2009-10-13 | Eidgenossische Technische Hochschule Zurich | Growth factor modified protein matrices for tissue engineering |
JP2003026673A (ja) * | 1999-03-05 | 2003-01-29 | Asahi Kasei Corp | 骨形成促進剤 |
JP3576063B2 (ja) | 2000-02-22 | 2004-10-13 | 株式会社ホギメディカル | 凝固蛋白質を含む可溶性創傷治癒止血セルロース繊維とその製造方法 |
EP1296724A1 (fr) * | 2000-06-22 | 2003-04-02 | Sam L. Austin | Compositions bioadhesives et methodes de preparation et d'utilisation |
US6921532B1 (en) | 2000-06-22 | 2005-07-26 | Spinal Restoration, Inc. | Biological Bioadhesive composition and methods of preparation and use |
US7247609B2 (en) | 2001-12-18 | 2007-07-24 | Universitat Zurich | Growth factor modified protein matrices for tissue engineering |
US8419722B2 (en) | 2004-10-29 | 2013-04-16 | Spinal Restoration, Inc. | Apparatus and method for injection of fibrin sealant in spinal applications |
US8124075B2 (en) | 2004-07-16 | 2012-02-28 | Spinal Restoration, Inc. | Enhanced biological autologous tissue adhesive composition and methods of preparation and use |
US8403923B2 (en) | 2004-10-29 | 2013-03-26 | Spinal Restoration, Inc. | Injection of fibrin sealant in the absence of corticosteroids in spinal applications |
US7597687B2 (en) | 2004-10-29 | 2009-10-06 | Spinal Restoration, Inc. | Injection of fibrin sealant including an anesthetic in spinal applications |
US8206448B2 (en) | 2004-10-29 | 2012-06-26 | Spinal Restoration, Inc. | Injection of fibrin sealant using reconstituted components in spinal applications |
US9358318B2 (en) | 2004-10-20 | 2016-06-07 | Ethicon, Inc. | Method of making a reinforced absorbable multilayered hemostatic wound dressing |
WO2006044882A2 (fr) * | 2004-10-20 | 2006-04-27 | Ethicon, Inc. | Pansement hemostatique multicouche absorbable renforce et son procede de fabrication |
WO2006073711A2 (fr) | 2005-01-06 | 2006-07-13 | Kuros Biosurgery Ag | Traitement local des deficits osseux |
US8575101B2 (en) | 2005-01-06 | 2013-11-05 | Kuros Biosurgery Ag | Supplemented matrices for the repair of bone fractures |
EP2399991B1 (fr) | 2005-04-12 | 2017-09-27 | Mesoblast, Inc. | Isolation des cellules multipotentes adultes par phosphatase alcaline non spécifique de tissus |
US7429241B2 (en) | 2005-09-29 | 2008-09-30 | Codman & Shurtleff, Inc. | Dural graft and method of preparing the same |
KR100701552B1 (ko) * | 2006-06-23 | 2007-03-30 | 한국과학기술연구원 | 압축기체를 이용한 필라멘트 및 시트 형태의 생분해성폴리에스테르 고분자 소재의 제조방법 |
GB0623607D0 (en) * | 2006-11-27 | 2007-01-03 | Haemostatix Ltd | Tissue adhesive |
JP5581056B2 (ja) | 2006-12-15 | 2014-08-27 | ライフボンド リミテッド | ゼラチン−トランスグルタミナーゼ止血ドレッシング及びシーラント |
WO2008125655A1 (fr) | 2007-04-13 | 2008-10-23 | Kuros Biosurgery Ag | Agent de scellement tissulaire polymère |
EP3424514B1 (fr) | 2007-08-06 | 2022-05-11 | Mesoblast, Inc. | Cellules précurseurs mésenchymales tnap+ pour l'utilisation dans le traitement de maladies tissulaires conjonctives |
EP2227263A2 (fr) | 2007-12-28 | 2010-09-15 | Kuros Biosurgery AG | Protéines hybrides du pdgf incorporées dans des mousses de fibrine |
JP5450612B2 (ja) | 2008-06-18 | 2014-03-26 | ライフボンド リミテッド | 改良された架橋組成物 |
JP5826629B2 (ja) | 2008-08-18 | 2015-12-02 | メゾブラスト,インコーポレーテッド | モノクローナル抗体stro−4 |
US9827205B2 (en) | 2008-12-12 | 2017-11-28 | Mallinckrodt Pharma Ip Trading D.A.C. | Dry powder fibrin sealant |
EP2515957B1 (fr) | 2009-12-22 | 2015-07-29 | Lifebond Ltd | Modification d'agents de réticulation enzymatiques pour la maîtrise des propriétés des matrices réticulées |
US8846105B2 (en) | 2010-01-08 | 2014-09-30 | Profibrix, B.V. | Dry powder fibrin sealant |
US8961544B2 (en) | 2010-08-05 | 2015-02-24 | Lifebond Ltd. | Dry composition wound dressings and adhesives comprising gelatin and transglutaminase in a cross-linked matrix |
WO2012123028A1 (fr) | 2011-03-16 | 2012-09-20 | Kuros Biosurgery Ag | Formulation pharmaceutique destinée à être utilisée dans une fusion des vertèbres |
US20130202675A1 (en) | 2012-02-03 | 2013-08-08 | Dynasil Biomedical Corporation | Systems and methods for the fabrication of tissue patches |
GB201400292D0 (en) | 2014-01-08 | 2014-02-26 | Haemostatix Ltd | Peptide dendrimers and agents |
US10751444B2 (en) | 2015-08-07 | 2020-08-25 | Victor Matthew Phillips | Flowable hemostatic gel composition and its methods of use |
US9833538B2 (en) | 2015-08-07 | 2017-12-05 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
US10660945B2 (en) | 2015-08-07 | 2020-05-26 | Victor Matthew Phillips | Flowable hemostatic gel composition and its methods of use |
WO2017027378A1 (fr) | 2015-08-07 | 2017-02-16 | Xcede Technologies, Inc. | Compositions adhésives et procédés associés |
KR101878769B1 (ko) | 2017-04-03 | 2018-08-16 | 조석형 | 저분자 cm-1,3-베타글루칸 칼슘염 분말 지혈제 |
DE102017126149A1 (de) * | 2017-11-08 | 2019-05-09 | Johannes Gutenberg-Universität Mainz | Wirkstoffhaltiger Schichtverbund sowie Verfahren zu dessen Herstellung |
US11998654B2 (en) | 2018-07-12 | 2024-06-04 | Bard Shannon Limited | Securing implants and medical devices |
AU2019344801A1 (en) * | 2018-09-17 | 2021-05-20 | Board Of Regents, The University Of Texas System | Compositions and methods for treating bone injury |
WO2021078986A1 (fr) * | 2019-10-23 | 2021-04-29 | Fibriant B.V. | Fibrinogène en tant qu'adjuvant pour agents antimicrobiens et thérapie |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4706662A (en) * | 1981-12-11 | 1987-11-17 | Johnson & Johnson Products, Inc. | Film dressing with fabric backing |
FR2589737A1 (fr) * | 1985-11-12 | 1987-05-15 | Dow Corning Sa | Procedes de fabrication de pansements |
DE69132918T2 (de) * | 1990-11-27 | 2002-10-31 | American Nat Red Cross Washing | Gewebeabdeckung und wachstumsfaktor enthaltende verbindungen zur förderung beschleunigter wundheilung |
US5206023A (en) * | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
GB9206509D0 (en) * | 1992-03-25 | 1992-05-06 | Jevco Ltd | Heteromorphic sponges containing active agents |
ES2225828T3 (es) * | 1993-03-12 | 2005-03-16 | The American National Red Cross | Sellantes de tejido suplementados, procedimientos de produccion y uso. |
-
1995
- 1995-12-06 JP JP51775396A patent/JP4223548B2/ja not_active Expired - Lifetime
- 1995-12-06 WO PCT/US1995/015876 patent/WO1996017633A1/fr active Application Filing
- 1995-12-06 CA CA002207289A patent/CA2207289C/fr not_active Expired - Lifetime
- 1995-12-06 EP EP95943692A patent/EP0796115A1/fr not_active Ceased
- 1995-12-06 AU AU45100/96A patent/AU717906B2/en not_active Withdrawn - After Issue
Also Published As
Publication number | Publication date |
---|---|
CA2207289C (fr) | 2005-04-12 |
JPH10510183A (ja) | 1998-10-06 |
CA2207289A1 (fr) | 1996-06-13 |
WO1996017633A1 (fr) | 1996-06-13 |
AU4510096A (en) | 1996-06-26 |
AU717906B2 (en) | 2000-04-06 |
EP0796115A1 (fr) | 1997-09-24 |
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