JP2022543537A - アクリルポリマーおよび接着剤組成物 - Google Patents
アクリルポリマーおよび接着剤組成物 Download PDFInfo
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- JP2022543537A JP2022543537A JP2022500929A JP2022500929A JP2022543537A JP 2022543537 A JP2022543537 A JP 2022543537A JP 2022500929 A JP2022500929 A JP 2022500929A JP 2022500929 A JP2022500929 A JP 2022500929A JP 2022543537 A JP2022543537 A JP 2022543537A
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- JP
- Japan
- Prior art keywords
- acrylate
- monomer component
- acrylic polymer
- vinyl
- weight percent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920000058 polyacrylate Polymers 0.000 title claims abstract description 42
- 239000000203 mixture Substances 0.000 title claims abstract description 27
- 230000001070 adhesive effect Effects 0.000 title description 18
- 239000000853 adhesive Substances 0.000 title description 17
- 239000000178 monomer Substances 0.000 claims abstract description 57
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims abstract description 39
- 125000005250 alkyl acrylate group Chemical group 0.000 claims abstract description 27
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims abstract description 11
- 229920001567 vinyl ester resin Polymers 0.000 claims abstract description 7
- 150000003512 tertiary amines Chemical class 0.000 claims abstract description 5
- 239000000758 substrate Substances 0.000 claims description 19
- -1 defoamers Substances 0.000 claims description 18
- 239000002904 solvent Substances 0.000 claims description 8
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 7
- GOXQRTZXKQZDDN-UHFFFAOYSA-N 2-Ethylhexyl acrylate Chemical compound CCCCC(CC)COC(=O)C=C GOXQRTZXKQZDDN-UHFFFAOYSA-N 0.000 claims description 7
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 7
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical group CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- JKNCOURZONDCGV-UHFFFAOYSA-N 2-(dimethylamino)ethyl 2-methylprop-2-enoate Chemical group CN(C)CCOC(=O)C(C)=C JKNCOURZONDCGV-UHFFFAOYSA-N 0.000 claims description 6
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims description 5
- SJIXRGNQPBQWMK-UHFFFAOYSA-N 2-(diethylamino)ethyl 2-methylprop-2-enoate Chemical compound CCN(CC)CCOC(=O)C(C)=C SJIXRGNQPBQWMK-UHFFFAOYSA-N 0.000 claims description 4
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical group COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 claims description 4
- 239000000654 additive Substances 0.000 claims description 4
- 239000003999 initiator Substances 0.000 claims description 4
- 239000004014 plasticizer Substances 0.000 claims description 4
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 claims description 3
- DXPPIEDUBFUSEZ-UHFFFAOYSA-N 6-methylheptyl prop-2-enoate Chemical compound CC(C)CCCCCOC(=O)C=C DXPPIEDUBFUSEZ-UHFFFAOYSA-N 0.000 claims description 3
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical compound CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 claims description 3
- SQTUYFKNCCBFRR-UHFFFAOYSA-N (2,4-dimethoxyphenyl)boronic acid Chemical compound COC1=CC=C(B(O)O)C(OC)=C1 SQTUYFKNCCBFRR-UHFFFAOYSA-N 0.000 claims description 2
- LTVUCOSIZFEASK-MPXCPUAZSA-N (3ar,4s,7r,7as)-3a-methyl-3a,4,7,7a-tetrahydro-4,7-methano-2-benzofuran-1,3-dione Chemical compound C([C@H]1C=C2)[C@H]2[C@H]2[C@]1(C)C(=O)OC2=O LTVUCOSIZFEASK-MPXCPUAZSA-N 0.000 claims description 2
- KNDQHSIWLOJIGP-UMRXKNAASA-N (3ar,4s,7r,7as)-rel-3a,4,7,7a-tetrahydro-4,7-methanoisobenzofuran-1,3-dione Chemical compound O=C1OC(=O)[C@@H]2[C@H]1[C@]1([H])C=C[C@@]2([H])C1 KNDQHSIWLOJIGP-UMRXKNAASA-N 0.000 claims description 2
- 229920002818 (Hydroxyethyl)methacrylate Polymers 0.000 claims description 2
- JAHNSTQSQJOJLO-UHFFFAOYSA-N 2-(3-fluorophenyl)-1h-imidazole Chemical compound FC1=CC=CC(C=2NC=CN=2)=C1 JAHNSTQSQJOJLO-UHFFFAOYSA-N 0.000 claims description 2
- DPBJAVGHACCNRL-UHFFFAOYSA-N 2-(dimethylamino)ethyl prop-2-enoate Chemical compound CN(C)CCOC(=O)C=C DPBJAVGHACCNRL-UHFFFAOYSA-N 0.000 claims description 2
- SVYHMICYJHWXIN-UHFFFAOYSA-N 2-[di(propan-2-yl)amino]ethyl 2-methylprop-2-enoate Chemical compound CC(C)N(C(C)C)CCOC(=O)C(C)=C SVYHMICYJHWXIN-UHFFFAOYSA-N 0.000 claims description 2
- WDQMWEYDKDCEHT-UHFFFAOYSA-N 2-ethylhexyl 2-methylprop-2-enoate Chemical compound CCCCC(CC)COC(=O)C(C)=C WDQMWEYDKDCEHT-UHFFFAOYSA-N 0.000 claims description 2
- MNZNJOQNLFEAKG-UHFFFAOYSA-N 2-morpholin-4-ylethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCN1CCOCC1 MNZNJOQNLFEAKG-UHFFFAOYSA-N 0.000 claims description 2
- GNSFRPWPOGYVLO-UHFFFAOYSA-N 3-hydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCCO GNSFRPWPOGYVLO-UHFFFAOYSA-N 0.000 claims description 2
- QZPSOSOOLFHYRR-UHFFFAOYSA-N 3-hydroxypropyl prop-2-enoate Chemical compound OCCCOC(=O)C=C QZPSOSOOLFHYRR-UHFFFAOYSA-N 0.000 claims description 2
- AYKYXWQEBUNJCN-UHFFFAOYSA-N 3-methylfuran-2,5-dione Chemical compound CC1=CC(=O)OC1=O AYKYXWQEBUNJCN-UHFFFAOYSA-N 0.000 claims description 2
- CYUZOYPRAQASLN-UHFFFAOYSA-N 3-prop-2-enoyloxypropanoic acid Chemical compound OC(=O)CCOC(=O)C=C CYUZOYPRAQASLN-UHFFFAOYSA-N 0.000 claims description 2
- JANUDBLANRHSLI-UHFFFAOYSA-N 5-butyl-1,3,4-oxadiazol-2-amine Chemical compound CCCCC1=NN=C(N)O1 JANUDBLANRHSLI-UHFFFAOYSA-N 0.000 claims description 2
- GDFCSMCGLZFNFY-UHFFFAOYSA-N Dimethylaminopropyl Methacrylamide Chemical compound CN(C)CCCNC(=O)C(C)=C GDFCSMCGLZFNFY-UHFFFAOYSA-N 0.000 claims description 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims description 2
- 239000003963 antioxidant agent Substances 0.000 claims description 2
- FWLDHHJLVGRRHD-UHFFFAOYSA-N decyl prop-2-enoate Chemical compound CCCCCCCCCCOC(=O)C=C FWLDHHJLVGRRHD-UHFFFAOYSA-N 0.000 claims description 2
- 239000003623 enhancer Substances 0.000 claims description 2
- WGXGKXTZIQFQFO-CMDGGOBGSA-N ethenyl (e)-3-phenylprop-2-enoate Chemical compound C=COC(=O)\C=C\C1=CC=CC=C1 WGXGKXTZIQFQFO-CMDGGOBGSA-N 0.000 claims description 2
- YCUBDDIKWLELPD-UHFFFAOYSA-N ethenyl 2,2-dimethylpropanoate Chemical compound CC(C)(C)C(=O)OC=C YCUBDDIKWLELPD-UHFFFAOYSA-N 0.000 claims description 2
- ZBVWCAOHSBLHRP-UHFFFAOYSA-N ethenyl 2-tert-butylbenzoate Chemical compound CC(C)(C)C1=CC=CC=C1C(=O)OC=C ZBVWCAOHSBLHRP-UHFFFAOYSA-N 0.000 claims description 2
- TVFJAZCVMOXQRK-UHFFFAOYSA-N ethenyl 7,7-dimethyloctanoate Chemical compound CC(C)(C)CCCCCC(=O)OC=C TVFJAZCVMOXQRK-UHFFFAOYSA-N 0.000 claims description 2
- PQLFROTZSIMBKR-UHFFFAOYSA-N ethenyl carbonochloridate Chemical compound ClC(=O)OC=C PQLFROTZSIMBKR-UHFFFAOYSA-N 0.000 claims description 2
- CMDXMIHZUJPRHG-UHFFFAOYSA-N ethenyl decanoate Chemical compound CCCCCCCCCC(=O)OC=C CMDXMIHZUJPRHG-UHFFFAOYSA-N 0.000 claims description 2
- AFSIMBWBBOJPJG-UHFFFAOYSA-N ethenyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC=C AFSIMBWBBOJPJG-UHFFFAOYSA-N 0.000 claims description 2
- BLZSRIYYOIZLJL-UHFFFAOYSA-N ethenyl pentanoate Chemical compound CCCCC(=O)OC=C BLZSRIYYOIZLJL-UHFFFAOYSA-N 0.000 claims description 2
- UIWXSTHGICQLQT-UHFFFAOYSA-N ethenyl propanoate Chemical compound CCC(=O)OC=C UIWXSTHGICQLQT-UHFFFAOYSA-N 0.000 claims description 2
- 239000000945 filler Substances 0.000 claims description 2
- LNMQRPPRQDGUDR-UHFFFAOYSA-N hexyl prop-2-enoate Chemical compound CCCCCCOC(=O)C=C LNMQRPPRQDGUDR-UHFFFAOYSA-N 0.000 claims description 2
- PBOSTUDLECTMNL-UHFFFAOYSA-N lauryl acrylate Chemical compound CCCCCCCCCCCCOC(=O)C=C PBOSTUDLECTMNL-UHFFFAOYSA-N 0.000 claims description 2
- LVHBHZANLOWSRM-UHFFFAOYSA-N methylenebutanedioic acid Natural products OC(=O)CC(=C)C(O)=O LVHBHZANLOWSRM-UHFFFAOYSA-N 0.000 claims description 2
- DCBBWYIVFRLKCD-UHFFFAOYSA-N n-[2-(dimethylamino)ethyl]-2-methylprop-2-enamide Chemical compound CN(C)CCNC(=O)C(C)=C DCBBWYIVFRLKCD-UHFFFAOYSA-N 0.000 claims description 2
- ADTJPOBHAXXXFS-UHFFFAOYSA-N n-[3-(dimethylamino)propyl]prop-2-enamide Chemical compound CN(C)CCCNC(=O)C=C ADTJPOBHAXXXFS-UHFFFAOYSA-N 0.000 claims description 2
- 229940065472 octyl acrylate Drugs 0.000 claims description 2
- ANISOHQJBAQUQP-UHFFFAOYSA-N octyl prop-2-enoate Chemical compound CCCCCCCCOC(=O)C=C ANISOHQJBAQUQP-UHFFFAOYSA-N 0.000 claims description 2
- ULDDEWDFUNBUCM-UHFFFAOYSA-N pentyl prop-2-enoate Chemical compound CCCCCOC(=O)C=C ULDDEWDFUNBUCM-UHFFFAOYSA-N 0.000 claims description 2
- 239000000049 pigment Substances 0.000 claims description 2
- 239000006254 rheological additive Substances 0.000 claims description 2
- KOZCZZVUFDCZGG-UHFFFAOYSA-N vinyl benzoate Chemical compound C=COC(=O)C1=CC=CC=C1 KOZCZZVUFDCZGG-UHFFFAOYSA-N 0.000 claims description 2
- FQYPKQOQUNFBDP-QMMMGPOBSA-N (2s)-6-amino-2-(2-methylprop-2-enoylamino)hexanoic acid Chemical compound CC(=C)C(=O)N[C@H](C(O)=O)CCCCN FQYPKQOQUNFBDP-QMMMGPOBSA-N 0.000 claims 1
- BEWCNXNIQCLWHP-UHFFFAOYSA-N 2-(tert-butylamino)ethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCNC(C)(C)C BEWCNXNIQCLWHP-UHFFFAOYSA-N 0.000 claims 1
- XSHISXQEKIKSGC-UHFFFAOYSA-N 2-aminoethyl 2-methylprop-2-enoate;hydron;chloride Chemical compound Cl.CC(=C)C(=O)OCCN XSHISXQEKIKSGC-UHFFFAOYSA-N 0.000 claims 1
- CFVWNXQPGQOHRJ-UHFFFAOYSA-N 2-methylpropyl prop-2-enoate Chemical compound CC(C)COC(=O)C=C CFVWNXQPGQOHRJ-UHFFFAOYSA-N 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- ZBGRMWIREQJHPK-UHFFFAOYSA-N ethenyl 2,2,2-trifluoroacetate Chemical compound FC(F)(F)C(=O)OC=C ZBGRMWIREQJHPK-UHFFFAOYSA-N 0.000 claims 1
- SUPCQIBBMFXVTL-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate Chemical compound CCOC(=O)C(C)=C SUPCQIBBMFXVTL-UHFFFAOYSA-N 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- DMEKUKDWAIXWSL-UHFFFAOYSA-N n,n-dimethyl-7-nitro-9h-fluoren-2-amine Chemical compound [O-][N+](=O)C1=CC=C2C3=CC=C(N(C)C)C=C3CC2=C1 DMEKUKDWAIXWSL-UHFFFAOYSA-N 0.000 claims 1
- RUSMHXACRXXLKQ-UHFFFAOYSA-N n-(2-aminoethyl)-2-methylprop-2-enamide;hydrochloride Chemical compound Cl.CC(=C)C(=O)NCCN RUSMHXACRXXLKQ-UHFFFAOYSA-N 0.000 claims 1
- XHIRWEVPYCTARV-UHFFFAOYSA-N n-(3-aminopropyl)-2-methylprop-2-enamide;hydrochloride Chemical compound Cl.CC(=C)C(=O)NCCCN XHIRWEVPYCTARV-UHFFFAOYSA-N 0.000 claims 1
- 239000002417 nutraceutical Substances 0.000 claims 1
- 235000021436 nutraceutical agent Nutrition 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 230000035515 penetration Effects 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- AWRLEXQNWFAMJM-UHFFFAOYSA-N tert-butyl 2-amino-4-(2-methylprop-2-enoylamino)butanoate Chemical compound CC(=C)C(=O)NCCC(N)C(=O)OC(C)(C)C AWRLEXQNWFAMJM-UHFFFAOYSA-N 0.000 claims 1
- 239000000080 wetting agent Substances 0.000 claims 1
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- 229920000642 polymer Polymers 0.000 description 9
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 8
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 description 6
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- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 3
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- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
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Abstract
Description
本発明は、これらに限定されない、医療デバイスを皮膚に接着するための接着剤、診断パッチ、経皮薬物送達パッチ、皮膚活性物質の送達のための皮膚パッチを含む皮膚接触用途に理想的に適するアクリルポリマーおよび感圧接着剤組成物、ならびにそれらの最終使用用途に関する。
接着剤組成物は、医療分野、例えば、様々なテープ、包帯、および薬物送達デバイスにおいて広く使用されている。これらのデバイスは、基材の少なくとも1つの表面上に形成された接着剤層を有し、接着剤層を介して標的皮膚表面に接着される。接着剤は感圧接着剤であり、室温で永久に粘着性があり、接着物を穏やかな圧力で皮膚に保持し、痛みを引き起こしたり接着剤の残留物を残したりすることなく容易に取り除くことができる。アプリケーションの目的に応じて、デバイスは、長期間にわたって皮膚表面への接着を確保することが必要である。これらのデバイスは通常、オストミーバッグ、包帯、診断用ビークル、および経皮パッチの形をしている。
本発明は、アクリルポリマーおよび接着剤組成物、ならびに特に医療用皮膚接触デバイスにおけるアクリルポリマーおよび接着剤組成物を含む製品に関する。
本明細書で使用される場合、「感圧接着剤」または「PSA」という用語は、わずかな圧力を加えることでほとんどの基材に瞬時に接着し、永久に粘着性を維持する粘弾性材料を指す。ポリマーは、それ自体が感圧接着剤の特性を有するか、または他の成分との混合によって感圧接着剤として機能する場合、本明細書で使用される用語の意味の範囲内の感圧接着剤である。本発明の感圧接着剤は、任意の数の用途、例えば、診断および経皮目的のためのラベル、テープ、医療用皮膚接触デバイステープに使用することができる。
(a)容器に1~約10の(i)カルボキシおよび/またはヒドロキシ官能性モノマー、(ii)約50~約90の低Tgアルキルアクリレートモノマー成分、(iii)約1~約20重量%の第三級アミン官能化アルキルアクリレートモノマー成分のモノマー混合物を形成し、
(b)容器に溶媒と開始剤を加え、
(c)容器を加熱し、および
(d)アクリルポリマーを分離する工程を含む。
434gの2-エチルヘキシルアクリレートと13gのアクリル酸を含む初期装入物を調製し、70gの2-エチルヘキシルアクリレート、3gのアクリル酸、123gの酢酸ビニル、84gのヘプタンおよび90gの酢酸エチルを含むステンレススチールスターラー、温度計、コンデンサー、ウォーターバス、および追加のファンネルを備えたフラスコにゆっくりと装入した。最初の装入物をAIBNを同時にゆっくり添加しながら、約3時間撹拌しながら、加熱して還流した。ヘプタンを数時間かけて加え、さらに1時間還流した。アセチルアセトノエートアルミニウム、2,4-ペンタンジオン、トルエン、およびイソプロパノールを添加した。この最後に、内容物を冷却し、イソプロピルアルコールで洗い流し、溶液中の架橋固体を調べた。
アクリルポリマーサンプルA、B、C、およびDは、例1コントロールと同様に作製したが、2-ジメチルエチルメタクリレート(2-DMAEMA)およびヒドロキシエチルアクリレート(HEMA)、ならびに無水マレイン酸(MA)の量を変えた。モノマーの重量パーセントは、コントロールサンプルの2-エチルヘキシルアクリレートのパーセンテージを直接置き換える。
せん断接着力は、PSTC No.107に従って、室温で1,000グラム(g)の質量を使用して測定した。接着面積は1インチ×0.5インチだった。結果は、結合が機能しなくなるのに必要な時間として報告される。
Claims (19)
- (i)約1~約10重量%のカルボキシ官能性モノマー成分、(ii)約50~約90量%の低Tgアルキルアクリレートモノマー成分、(iii)約1~約20重量%の第三級アミン官能化アルキルアクリレートモノマー成分、および(iv)任意に、最大50重量%のビニルエステルモノマー成分から調製されるアクリルポリマー。
- (i)カルボキシ官能性モノマー成分が、アクリル酸、メタクリル酸、イタコン酸、β-カルボキシエチルアクリレート、およびそれらの混合物からなる群から選択される、請求項1に記載のアクリルポリマー。
- (ii)低Tgアルキルアクリレートモノマー成分が、メチルアクリレート、ブチルアクリレート、イソブチルアクリレート、アミルアクリレート、ヘキシルアクリレート、2-エチルヘキシルアクリレート、オクチルアクリレート、イソオクチルアクリレート、デシルアクリレート、ドデシルアクリレート、およびそれらの異性体および混合物からなる群から選択される、請求項1に記載のアクリルポリマー。
- (iii)第三級アミン官能化アルキルアクリレートモノマー成分が、2-ジメチルアミノエチルメタクリレート、2-N-モルホリノエチルアクリレート、2-N-モルホリノエチルメタクリレート、2-ジイソプロピルアミノエチルメタクリレート、N-(3-アミノプロピル)メタクリルアミド塩酸塩、N-(3-BOC-アミノプロピル)メタクリルアミド、2-アミノエチルメタクリレート塩酸塩、メタクリロイル-L-リジン、N-[3-(N,N-ジメチルアミノ)プロピル]メタクリルアミド、N-(2-アミノエチル)メタクリルアミド塩酸塩、N-[2-(N,N-ジメチルアミノ)エチル]メタクリルアミド、N-[3-(N,N-ジメチルアミノ)プロピル]アクリルアミド、min,95%、2-(N,N-ジメチルアミノ)エチルアクリレート、2-(N,N-ジエチルアミノ)エチルメタクリレート、2-(tert-ブチルアミノ)エチルメタクリレート、2-(N,N-ジメチルアミノ)エチルメタクリレート、2-アクリロキシエチルトリメチルアンモニウム塩化物である、請求項1に記載のアクリルポリマー。
- (iii)第三級アミン官能化アルキルアクリレートモノマー成分が、2-ジメチルアミノエチルメタクリレートである、請求項4に記載のアクリルポリマー。
- (iv)ビニルエステルモノマー成分が、酢酸ビニル、安息香酸ビニル、tert-ブチル安息香酸ビニル、クロロギ酸ビニル、桂皮酸ビニル、デカン酸ビニル、ネオデカン酸ビニル、ピバリン酸ビニル、プロピオン酸ビニル、ステアリン酸ビニル、トリフロロ酢酸ビニル、吉草酸ビニル、およびそれらの混合物からなる群から選択される、請求項1に記載のアクリルポリマー。
- ヒドロキシ官能性モノマー成分およびその誘導体をさらに含む、請求項1に記載のアクリルポリマー。
- ヒドロキシ官能性モノマー成分が、ヒドロキシエチルアクリレート、ヒドロキシプロピルアクリレート、ヒドロキシエチルメタクリレートおよびヒドロキシプロピルメタクリレート、ならびにそれらの混合物からなる群から選択される、請求項7に記載のアクリルポリマー。
- 無水物官能性モノマー成分およびその誘導体をさらに含む、請求項1に記載のアクリルポリマー。
- 無水物官能性モノマー成分が、無水マレイン酸、無水ナド酸、無水マレイン酸メチル、無水ナド酸メチルまたはそれらの誘導体からなる群から選択される、請求項9に記載のアクリルポリマー。
- (i)約1~約10重量%のアクリル酸、(ii)約50~約90重量%の2-エチルヘキシルメタクリレート、(iii)約1~約20重量%の2-ジメチルアミノエチルメタクリレートおよび(iv)最大約50重量%の酢酸ビニルを含む、請求項1に記載のアクリルポリマー。
- 約1~約10の(i)カルボキシおよび/またはヒドロキシ官能性モノマー、(ii)約50~約90の低Tgアルキルアクリレートモノマー成分、(iii)約1~約20重量%の第三級アミン官能化アルキルアクリレートモノマーから調製されるアクリルポリマーを含む感圧接着剤組成物。
- 粘着付与剤、可塑剤、顔料、充填剤、蛍光剤、流動剤、湿潤剤、界面活性剤、消泡剤、レオロジー調整剤、浸透促進剤、安定剤、抗酸化剤およびそれらの混合物からなる群から選択される添加剤をさらに含む、請求項12に記載の感圧接着剤組成物。
- 医薬および/または栄養補助食品活性物質をさらに含む、請求項12に記載の感圧接着剤組成物。
- 請求項12に記載の感圧接着剤を含む製品。
- 皮膚に接着接合される、請求項15に記載の製品。
- 感圧接着剤が、基材と剥離ライナーとの間にある、バッキング基材および剥離ライナーを備えた、請求項15に記載の製品。
- テープ、膏薬、または包帯である、請求項17に記載の製品。
- a)容器に1~約10の(i)カルボキシおよび/またはヒドロキシ官能性モノマー、(ii)約50~約90の低Tgアルキルアクリレートモノマー成分、(iii)約1~約20重量%の第三級アミン官能化アルキルアクリレートモノマー成分のモノマー混合物を形成し、
b)容器に溶媒と開始剤を加え、
c)容器を加熱し、
d)アクリルポリマーを分離する工程を含むアクリルポリマーを形成する方法。
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