JP2020094106A - Spray composition - Google Patents
Spray composition Download PDFInfo
- Publication number
- JP2020094106A JP2020094106A JP2018231783A JP2018231783A JP2020094106A JP 2020094106 A JP2020094106 A JP 2020094106A JP 2018231783 A JP2018231783 A JP 2018231783A JP 2018231783 A JP2018231783 A JP 2018231783A JP 2020094106 A JP2020094106 A JP 2020094106A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- spraying
- mass
- acid ester
- benzoic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 138
- 239000007921 spray Substances 0.000 title claims abstract description 47
- 238000005507 spraying Methods 0.000 claims abstract description 79
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims abstract description 45
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 32
- 239000002736 nonionic surfactant Substances 0.000 claims abstract description 26
- -1 Benzoic acid ester Chemical class 0.000 claims description 58
- 239000005711 Benzoic acid Substances 0.000 claims description 42
- 235000010233 benzoic acid Nutrition 0.000 claims description 42
- 230000005484 gravity Effects 0.000 claims description 17
- 238000002834 transmittance Methods 0.000 claims description 8
- 206010011224 Cough Diseases 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 description 20
- 239000003921 oil Substances 0.000 description 17
- 235000019198 oils Nutrition 0.000 description 16
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 14
- 239000007924 injection Substances 0.000 description 13
- 238000002347 injection Methods 0.000 description 13
- 239000004480 active ingredient Substances 0.000 description 12
- SESFRYSPDFLNCH-UHFFFAOYSA-N benzyl benzoate Chemical compound C=1C=CC=CC=1C(=O)OCC1=CC=CC=C1 SESFRYSPDFLNCH-UHFFFAOYSA-N 0.000 description 10
- 239000000047 product Substances 0.000 description 10
- 150000005846 sugar alcohols Polymers 0.000 description 10
- 229920003169 water-soluble polymer Polymers 0.000 description 10
- 239000003380 propellant Substances 0.000 description 9
- 230000000052 comparative effect Effects 0.000 description 8
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 7
- 239000004359 castor oil Substances 0.000 description 7
- 235000019438 castor oil Nutrition 0.000 description 7
- 239000000284 extract Substances 0.000 description 7
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 7
- 235000014113 dietary fatty acids Nutrition 0.000 description 6
- 239000000194 fatty acid Substances 0.000 description 6
- 229930195729 fatty acid Natural products 0.000 description 6
- 229960002903 benzyl benzoate Drugs 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 238000011156 evaluation Methods 0.000 description 5
- 239000002245 particle Substances 0.000 description 5
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 4
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 4
- 229910052757 nitrogen Inorganic materials 0.000 description 4
- 230000035699 permeability Effects 0.000 description 4
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 229920001214 Polysorbate 60 Polymers 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000002781 deodorant agent Substances 0.000 description 3
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 3
- 230000008016 vaporization Effects 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 2
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 2
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical compound C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 description 2
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 description 2
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 229920002307 Dextran Polymers 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 229920002907 Guar gum Polymers 0.000 description 2
- UUGLJVMIFJNVFH-UHFFFAOYSA-N Hexyl benzoate Chemical compound CCCCCCOC(=O)C1=CC=CC=C1 UUGLJVMIFJNVFH-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 239000004166 Lanolin Substances 0.000 description 2
- CRZQGDNQQAALAY-UHFFFAOYSA-N Methyl benzeneacetate Chemical compound COC(=O)CC1=CC=CC=C1 CRZQGDNQQAALAY-UHFFFAOYSA-N 0.000 description 2
- GQPLMRYTRLFLPF-UHFFFAOYSA-N Nitrous Oxide Chemical compound [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 2
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 241000607479 Yersinia pestis Species 0.000 description 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000003570 air Substances 0.000 description 2
- 229960000458 allantoin Drugs 0.000 description 2
- RDOXTESZEPMUJZ-UHFFFAOYSA-N anisole Chemical compound COC1=CC=CC=C1 RDOXTESZEPMUJZ-UHFFFAOYSA-N 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- CUFNKYGDVFVPHO-UHFFFAOYSA-N azulene Chemical compound C1=CC=CC2=CC=CC2=C1 CUFNKYGDVFVPHO-UHFFFAOYSA-N 0.000 description 2
- QUKGYYKBILRGFE-UHFFFAOYSA-N benzyl acetate Chemical compound CC(=O)OCC1=CC=CC=C1 QUKGYYKBILRGFE-UHFFFAOYSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 description 2
- 150000002148 esters Chemical group 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 235000010417 guar gum Nutrition 0.000 description 2
- 239000000665 guar gum Substances 0.000 description 2
- 229960002154 guar gum Drugs 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 2
- 239000002917 insecticide Substances 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 229940039717 lanolin Drugs 0.000 description 2
- 235000019388 lanolin Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000003595 mist Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 239000005871 repellent Substances 0.000 description 2
- 230000002940 repellent Effects 0.000 description 2
- 229960003471 retinol Drugs 0.000 description 2
- 239000011607 retinol Substances 0.000 description 2
- 235000020944 retinol Nutrition 0.000 description 2
- 230000003381 solubilizing effect Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- HLZKNKRTKFSKGZ-UHFFFAOYSA-N tetradecan-1-ol Chemical compound CCCCCCCCCCCCCCO HLZKNKRTKFSKGZ-UHFFFAOYSA-N 0.000 description 2
- 229960000984 tocofersolan Drugs 0.000 description 2
- 238000009834 vaporization Methods 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- NOOLISFMXDJSKH-KXUCPTDWSA-N (-)-Menthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O NOOLISFMXDJSKH-KXUCPTDWSA-N 0.000 description 1
- DEQUKPCANKRTPZ-UHFFFAOYSA-N (2,3-dihydroxyphenyl)-phenylmethanone Chemical compound OC1=CC=CC(C(=O)C=2C=CC=CC=2)=C1O DEQUKPCANKRTPZ-UHFFFAOYSA-N 0.000 description 1
- ATCDSAIMQFVYAG-UHFFFAOYSA-N (2,3-dihydroxyphenyl)-phenylmethanone;sodium Chemical compound [Na].OC1=CC=CC(C(=O)C=2C=CC=CC=2)=C1O ATCDSAIMQFVYAG-UHFFFAOYSA-N 0.000 description 1
- HJIAMFHSAAEUKR-UHFFFAOYSA-N (2-hydroxyphenyl)-phenylmethanone Chemical compound OC1=CC=CC=C1C(=O)C1=CC=CC=C1 HJIAMFHSAAEUKR-UHFFFAOYSA-N 0.000 description 1
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 description 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- WLAUCMCTKPXDIY-JXMROGBWSA-N (2e)-1-chloro-3,7-dimethylocta-2,6-diene Chemical compound CC(C)=CCC\C(C)=C\CCl WLAUCMCTKPXDIY-JXMROGBWSA-N 0.000 description 1
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- QMMJWQMCMRUYTG-UHFFFAOYSA-N 1,2,4,5-tetrachloro-3-(trifluoromethyl)benzene Chemical compound FC(F)(F)C1=C(Cl)C(Cl)=CC(Cl)=C1Cl QMMJWQMCMRUYTG-UHFFFAOYSA-N 0.000 description 1
- 229940058015 1,3-butylene glycol Drugs 0.000 description 1
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- JMBWBOKFMJWVCU-UHFFFAOYSA-N 1-phenylethanone;tetradecanoic acid Chemical compound CC(=O)C1=CC=CC=C1.CCCCCCCCCCCCCC(O)=O JMBWBOKFMJWVCU-UHFFFAOYSA-N 0.000 description 1
- LGEZTMRIZWCDLW-UHFFFAOYSA-N 14-methylpentadecyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC(C)C LGEZTMRIZWCDLW-UHFFFAOYSA-N 0.000 description 1
- SPSPIUSUWPLVKD-UHFFFAOYSA-N 2,3-dibutyl-6-methylphenol Chemical compound CCCCC1=CC=C(C)C(O)=C1CCCC SPSPIUSUWPLVKD-UHFFFAOYSA-N 0.000 description 1
- XFOQWQKDSMIPHT-UHFFFAOYSA-N 2,3-dichloro-6-(trifluoromethyl)pyridine Chemical compound FC(F)(F)C1=CC=C(Cl)C(Cl)=N1 XFOQWQKDSMIPHT-UHFFFAOYSA-N 0.000 description 1
- 239000000263 2,3-dihydroxypropyl (Z)-octadec-9-enoate Substances 0.000 description 1
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 1
- QGLVWTFUWVTDEQ-UHFFFAOYSA-N 2-chloro-3-methoxyphenol Chemical compound COC1=CC=CC(O)=C1Cl QGLVWTFUWVTDEQ-UHFFFAOYSA-N 0.000 description 1
- OUCGLXKNITVPJS-OUKQBFOZSA-N 2-ethylhexyl (e)-3-phenylprop-2-enoate Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=CC=C1 OUCGLXKNITVPJS-OUKQBFOZSA-N 0.000 description 1
- JGUMTYWKIBJSTN-UHFFFAOYSA-N 2-ethylhexyl 4-[[4,6-bis[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 JGUMTYWKIBJSTN-UHFFFAOYSA-N 0.000 description 1
- BGRXBNZMPMGLQI-UHFFFAOYSA-N 2-octyldodecyl tetradecanoate Chemical compound CCCCCCCCCCCCCC(=O)OCC(CCCCCCCC)CCCCCCCCCC BGRXBNZMPMGLQI-UHFFFAOYSA-N 0.000 description 1
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
- MLLAPOCBLWUFAP-UHFFFAOYSA-N 3-Methylbutyl benzoate Chemical compound CC(C)CCOC(=O)C1=CC=CC=C1 MLLAPOCBLWUFAP-UHFFFAOYSA-N 0.000 description 1
- RZRNAYUHWVFMIP-GDCKJWNLSA-N 3-oleoyl-sn-glycerol Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](O)CO RZRNAYUHWVFMIP-GDCKJWNLSA-N 0.000 description 1
- HBTAOSGHCXUEKI-UHFFFAOYSA-N 4-chloro-n,n-dimethyl-3-nitrobenzenesulfonamide Chemical compound CN(C)S(=O)(=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 HBTAOSGHCXUEKI-UHFFFAOYSA-N 0.000 description 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- 240000001548 Camellia japonica Species 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 235000001815 DL-alpha-tocopherol Nutrition 0.000 description 1
- 239000011627 DL-alpha-tocopherol Substances 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- RDOFJDLLWVCMRU-UHFFFAOYSA-N Diisobutyl adipate Chemical compound CC(C)COC(=O)CCCCC(=O)OCC(C)C RDOFJDLLWVCMRU-UHFFFAOYSA-N 0.000 description 1
- IUMSDRXLFWAGNT-UHFFFAOYSA-N Dodecamethylcyclohexasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 IUMSDRXLFWAGNT-UHFFFAOYSA-N 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- 239000001263 FEMA 3042 Substances 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 229920002148 Gellan gum Polymers 0.000 description 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- MPDGHEJMBKOTSU-UHFFFAOYSA-N Glycyrrhetinsaeure Natural products C12C(=O)C=C3C4CC(C)(C(O)=O)CCC4(C)CCC3(C)C1(C)CCC1C2(C)CCC(O)C1(C)C MPDGHEJMBKOTSU-UHFFFAOYSA-N 0.000 description 1
- 239000004378 Glycyrrhizin Substances 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
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Abstract
Description
本発明は、噴霧用組成物に関する。より詳細には、本発明は、均一な組成で噴霧することができ、かつ、使用者がむせにくい噴霧用組成物に関する。 The present invention relates to spray compositions. More specifically, the present invention relates to a spraying composition that can be sprayed with a uniform composition and that is difficult for the user to chew.
従来、安息香酸エステルを殺虫剤、害虫忌避剤、芳香剤、消臭剤等として含む、噴霧用組成物が開発されている。しかしながら、安息香酸エステルは、水よりも比重が大きく、分離すると容器内に沈降する。そのため、このような噴霧用組成物は、均一な組成で噴霧することが難しい。そこで、特許文献１には、エタノールと少量の水を配合し、界面活性剤で均一化した定量噴霧型のエアゾール剤が提案されている。 BACKGROUND ART Conventionally, a spray composition containing a benzoic acid ester as an insecticide, a pest repellent, an aromatic, a deodorant, etc. has been developed. However, benzoic acid ester has a larger specific gravity than water, and when separated, it precipitates in the container. Therefore, it is difficult to spray such a spraying composition with a uniform composition. Therefore, Patent Document 1 proposes a metered-spray type aerosol agent in which ethanol and a small amount of water are mixed and homogenized with a surfactant.
しかしながら、特許文献１に記載のエアゾール剤は、水を多く含む場合に安息香酸エステルが溶けにくく、沈降しやすい。特許文献１に記載のエアゾール剤は、特に低温条件において、内容物が分離しやすい。そのため、特許文献１に記載のエアゾール剤は、均一な組成で噴霧することが難しい。さらに、不均一な組成で噴霧された粒子は、含まれる有効成分に濃度差ができやすい。この場合、使用者等は、噴霧された粒子を吸い込むと、むせやすい。 However, when the aerosol agent described in Patent Document 1 contains a large amount of water, the benzoic acid ester hardly dissolves and easily precipitates. The aerosol agent described in Patent Document 1 is easy to separate the contents particularly under low temperature conditions. Therefore, it is difficult to spray the aerosol agent described in Patent Document 1 with a uniform composition. Furthermore, particles sprayed with a non-uniform composition are likely to cause a concentration difference in the contained active ingredients. In this case, the user or the like easily inhales the inhaled sprayed particles.
本発明は、このような従来の課題に鑑みてなされたものであり、均一な組成で噴霧することができ、かつ、使用者がむせにくい噴霧用組成物を提供することを目的とする。 The present invention has been made in view of such conventional problems, and an object of the present invention is to provide a spraying composition that can be sprayed with a uniform composition and that is difficult for the user to chew.
上記課題を解決する本発明には、以下の構成が主に含まれる。 The present invention for solving the above problems mainly includes the following configurations.
（１）安息香酸エステルと、ノニオン性界面活性剤と、アルコールと、水とを含み、均一相を形成する、噴霧用組成物。 (1) A spraying composition containing a benzoic acid ester, a nonionic surfactant, an alcohol, and water to form a uniform phase.
このような構成によれば、噴霧用組成物は、たとえば、ポンプ容器に充填してポンプ噴射を行ったり、圧縮ガスとともにエアゾール容器に充填してエアゾール噴射を行うことができる均一相を形成しており、均一な組成で噴霧されやすい。この際、噴霧用組成物は、使用者等をむせさせにくい。 According to such a configuration, the spraying composition forms a uniform phase that can be filled in a pump container for pump injection, or filled with a compressed gas in an aerosol container for aerosol injection. It has a uniform composition and is easily sprayed. At this time, the composition for spraying is unlikely to cause the user to suffer.
（２）２０℃における透過度が５０％以上である、（１）記載の噴霧用組成物。 (2) The composition for spraying according to (1), which has a transmittance at 20° C. of 50% or more.
このような構成によれば、噴霧用組成物は、透過度が高く、温度変化に対する安定性が高く、より均一な均一相が形成されている。そのため、噴霧用組成物は、より均一な組成で噴霧されやすい。 According to such a configuration, the spray composition has high permeability, high stability against temperature change, and a more uniform uniform phase is formed. Therefore, the spraying composition is likely to be sprayed with a more uniform composition.
（３）前記安息香酸エステルの比重は、水の比重よりも大きい、（１）または（２）記載の噴霧用組成物。 (3) The composition for spraying according to (1) or (2), wherein the specific gravity of the benzoic acid ester is higher than the specific gravity of water.
このような構成によれば、噴射された粒子（以下、噴射物という）は、揮発しやすいアルコールが気化することによって、噴射物中で安息香酸エステルが分離する。この場合、分離した安息香酸エステルは、比重が水の比重よりも大きいため、下層に移行しやすくなる。その結果、安息香酸エステルは、カーペット、畳、布団などの敷物や、ソファ、イスなどの置物、カーテン、衣類などの布製品などの噴射対象にしみ込みやすく、安息香酸エステルの効果が発揮されやすい。 According to such a configuration, in the ejected particles (hereinafter, referred to as an ejected substance), the benzoic acid ester is separated in the ejected substance by vaporizing the volatile alcohol. In this case, since the separated benzoic acid ester has a specific gravity larger than that of water, it tends to move to the lower layer. As a result, benzoate easily penetrates into rugs such as carpets, tatami mats, and futons, and objects such as sofas and chairs, curtains, and cloth products such as clothes. ..
（４）前記ノニオン性界面活性剤のＨＬＢは、７〜１８である、（１）〜（３）のいずれかに記載の噴霧用組成物。 (4) The composition for spraying according to any of (1) to (3), wherein the nonionic surfactant has an HLB of 7 to 18.
このような構成によれば、噴霧用組成物は、安息香酸エステル、アルコールおよび水が均一相を形成しやすい。そのため、噴霧用組成物は、より均一な組成で噴霧されやすい。 According to such a configuration, in the spraying composition, the benzoic acid ester, the alcohol and the water easily form a uniform phase. Therefore, the spraying composition is likely to be sprayed with a more uniform composition.
（５）前記ノニオン性界面活性剤の含有量（質量％）は、前記安息香酸エステルの含有量（質量％）の２倍以上である、（１）〜（４）のいずれかに記載の噴霧用組成物。 (5) The spray according to any one of (1) to (4), wherein the content (% by mass) of the nonionic surfactant is at least twice the content (% by mass) of the benzoic acid ester. Composition.
このような構成によれば、噴霧用組成物は、安息香酸エステルを可溶化させやすく、均一相を形成しやすい。 According to such a configuration, the composition for spraying easily solubilizes the benzoic acid ester and easily forms a uniform phase.
（６）前記アルコールの含有量は、前記噴霧用組成物中、０．１〜４０質量％である、（１）〜（５）のいずれかに記載の噴霧用組成物。 (6) The spray composition according to any one of (1) to (5), wherein the content of the alcohol is 0.1 to 40 mass% in the spray composition.
このような構成によれば、噴霧用組成物は、アルコールの含有量が少なくても均一相を形成することができ、さらに引火性が低い。そのため、噴霧用組成物は、火気に対する安全性が優れる。 According to such a configuration, the spraying composition can form a homogeneous phase even if the content of alcohol is low, and the flammability is low. Therefore, the composition for spraying has excellent safety against fire.
（７）前記水の含有量は、前記噴霧用組成物中、５０〜９９．５質量％である、（１）〜（６）のいずれかに記載の噴霧用組成物。 (7) The spray composition according to any one of (1) to (6), wherein the content of water is 50 to 99.5 mass% in the spray composition.
このような構成によれば、噴霧用組成物は、引火性が低い。そのため、噴霧用組成物は、火気に対する安全性が優れる。 With such a configuration, the spray composition has low flammability. Therefore, the composition for spraying has excellent safety against fire.
本発明によれば、均一な組成で噴霧することができ、かつ、使用者がむせにくい噴霧用組成物を提供することができる。 According to the present invention, it is possible to provide a spray composition that can be sprayed with a uniform composition and that is difficult for the user to chew.
＜噴霧用組成物＞
本発明の一実施形態の噴霧用組成物は、安息香酸エステルと、ノニオン性界面活性剤と、アルコールと、水とを含む。また、噴霧用組成物は、均一相を形成する。以下、それぞれについて説明する。
<Spraying composition>
The spray composition of one embodiment of the present invention contains a benzoic acid ester, a nonionic surfactant, an alcohol, and water. The spray composition also forms a homogeneous phase. Each will be described below.
（安息香酸エステル）
安息香酸エステルは、殺虫剤、害虫忌避剤、芳香剤、消臭剤等の有効成分として配合される。
(Benzoic acid ester)
Benzoic acid ester is blended as an active ingredient such as an insecticide, a pest repellent, an aromatic and a deodorant.
安息香酸エステルは特に限定されない。一例を挙げると、安息香酸エステルは、安息香酸ベンジル（比重：１．１２）、安息香酸アミル（比重：０．９９）、安息香酸イソアミル（比重：０．９９）、安息香酸ヘキシル（比重：０．９８）、安息香酸シクロヘキシル（比重：１．０４）、安息香酸−３−ヘキセニル（比重：１．００）等である。これらの中でも、安息香酸エステルは、比重が水の比重よりも大きいものを用いることが好ましく、特に、安息香酸ベンジルであることが好ましい。安息香酸エステルは、併用されてもよい。水の比重よりも、比重の大きな安息香酸エステルを用いる場合、噴射された粒子（以下、噴射物という）は、揮発しやすいアルコールが気化することによって、噴射物中で安息香酸エステルが分離する。この場合、分離した安息香酸エステルは、比重が水の比重よりも大きいため、下層に移行しやすくなる。その結果、安息香酸エステルは、カーペット、畳、布団などの敷物や、ソファ、イスなどの置物、カーテン、衣類などの布製品などの噴射対象にしみ込みやすく、安息香酸エステルの効果が発揮されやすい。 The benzoic acid ester is not particularly limited. As an example, benzoic acid esters include benzyl benzoate (specific gravity: 1.12), amyl benzoate (specific gravity: 0.99), isoamyl benzoate (specific gravity: 0.99), hexyl benzoate (specific gravity: 0). .98), cyclohexyl benzoate (specific gravity: 1.04), and 3-hexenyl benzoate (specific gravity: 1.00). Among these, as the benzoic acid ester, those having a specific gravity larger than that of water are preferably used, and benzyl benzoate is particularly preferable. The benzoic acid ester may be used in combination. When a benzoic acid ester having a specific gravity larger than that of water is used, in the sprayed particles (hereinafter referred to as a sprayed product), the benzoic acid ester is separated in the sprayed product by vaporization of the volatile alcohol. In this case, since the separated benzoic acid ester has a specific gravity larger than that of water, it tends to move to the lower layer. As a result, benzoate easily penetrates into rugs such as carpets, tatami mats, and futons, and objects such as sofas and chairs, curtains, and cloth products such as clothes. ..
安息香酸エステルの含有量は特に限定されない。一例を挙げると、安息香酸エステルの含有量は、噴霧用組成物中、０．０１質量％以上であることが好ましく、０．０５質量％以上であることがより好ましい。また、安息香酸エステルの含有量は、噴霧用組成物中、５質量％以下であることが好ましく、３質量％以下であることがより好ましい。安息香酸エステルの含有量が上記範囲内であることにより、噴霧用組成物は、均一相を形成しやすく、安息香酸エステルの効果が得られやすい。 The content of benzoic acid ester is not particularly limited. As an example, the content of the benzoic acid ester is preferably 0.01% by mass or more, and more preferably 0.05% by mass or more in the composition for spraying. Further, the content of the benzoic acid ester in the composition for spraying is preferably 5% by mass or less, more preferably 3% by mass or less. When the content of the benzoic acid ester is within the above range, the composition for spraying easily forms a uniform phase, and the effect of the benzoic acid ester is easily obtained.
安息香酸エステルとして、水よりも比重が大きい（２０℃における比重１．００１〜１．３程度）ものを用いる場合、安息香酸エステルは、噴霧用組成物が容器に充填された状態で分離すると、容器底部に沈降しやすい。ところで、容器には、噴霧用組成物をポンプバルブやエアゾールバルブに取り込むためのチューブが設けられる場合がある。このようなチューブは、一般に、容器の内底面に先端の開口が配置され、この開口から噴霧用組成物が取り込まれる。そのため、安息香酸エステルが分離して容器底部に沈降している場合、チューブからは、安息香酸エステルを多く含む不均一な噴霧用組成物が取り込まれやすい。これに対し、本実施形態の噴霧用組成物は、均一相を形成している。その結果、噴霧用組成物は、均一な組成で噴霧されやすい。 When a benzoic acid ester having a specific gravity larger than that of water (specific gravity of about 1.001 to 1.3 at 20° C.) is used, the benzoic acid ester is separated when the composition for spraying is filled in a container, Easy to settle at the bottom of the container. By the way, the container may be provided with a tube for taking the spraying composition into a pump valve or an aerosol valve. In such a tube, an opening at the tip is generally arranged on the inner bottom surface of the container, and the spraying composition is taken in from this opening. Therefore, when the benzoic acid ester is separated and settles on the bottom of the container, the non-uniform spraying composition containing a large amount of the benzoic acid ester is likely to be taken in from the tube. On the other hand, the spray composition of this embodiment forms a uniform phase. As a result, the spray composition tends to be sprayed with a uniform composition.
（ノニオン性界面活性剤）
ノニオン性界面活性剤は、安息香酸エステルや香料等の油剤を噴霧用組成物中に可溶化させて均一相を形成するために配合される。
(Nonionic surfactant)
The nonionic surfactant is added to solubilize an oil agent such as benzoic acid ester or a fragrance in the composition for spraying to form a uniform phase.
ノニオン性界面活性剤は特に限定されない。一例を挙げると、ノニオン性界面活性剤は、ＰＯＥ（３０）硬化ヒマシ油、ＰＯＥ（４０）硬化ヒマシ油、ＰＯＥ（６０）硬化ヒマシ油、ＰＯＥ（８０）硬化ヒマシ油、ＰＯＥ（１００）硬化ヒマシ油などのポリオキシエチレン硬化ヒマシ油、モノヤシ油脂肪酸ＰＯＥソルビタン、モノステアリン酸ＰＯＥソルビタンなどのポリオキシエチレンソルビタン脂肪酸エステル、モノステアリン酸ＰＯＥグリセリル、モノオレイン酸ＰＯＥグリセリルなどのポリオキシエチレングリセリル脂肪酸エステルなどのエーテル・エステル型；ＰＯＥモノラウレート、ＰＯＥモノステアレート、ＰＯＥモノオレエートなどのポリオキシエチレン脂肪酸エステル、モノラウリン酸ヘキサグリセリル、モノミリスチン酸ヘキサグリセリル、モノラウリン酸デカグルセリル、モノミリスチン酸デカグリセリル、モノステアリン酸デカグリセリル、モノイソステアリン酸デカグリセリル、モノリノール酸デカグリセリルなどのポリグリセリン脂肪酸エステルなどのエステル型等である。これらの中でも、ノニオン性界面活性剤は、安息香酸エステルを噴霧用組成物中に可溶化しやすく、均一相を形成しやすい点から、エーテル・エステル型であることが好ましく、特にポリオキシエチレン硬化ヒマシ油であることが好ましい。ノニオン性界面活性剤は、併用されてもよい。 The nonionic surfactant is not particularly limited. As an example, the nonionic surfactant is POE (30) hydrogenated castor oil, POE (40) hydrogenated castor oil, POE (60) hydrogenated castor oil, POE (80) hydrogenated castor oil, POE (100) hydrogenated castor oil. Polyoxyethylene hydrogenated castor oil such as oil, monococonut oil fatty acid POE sorbitan, polyoxyethylene sorbitan fatty acid ester such as POE sorbitan monostearate, POE glyceryl monostearate, polyoxyethylene glyceryl fatty acid ester such as POE glyceryl monooleate, etc. Ether ester type; polyoxyethylene fatty acid ester such as POE monolaurate, POE monostearate, POE monooleate, hexaglyceryl monolaurate, hexaglyceryl monomyristate, decaglyceryl monolaurate, decaglyceryl monomyristate, monostearic acid It is an ester type such as polyglycerin fatty acid ester such as decaglyceryl, decaglyceryl monoisostearate and decaglyceryl monolinoleate. Among these, the nonionic surfactant is preferably an ether/ester type, particularly from the viewpoint of easily solubilizing the benzoic acid ester in the composition for spraying and forming a uniform phase, and particularly polyoxyethylene curing It is preferably castor oil. The nonionic surfactant may be used in combination.
ノニオン性界面活性剤のＨＬＢは特に限定されない。一例を挙げると、ノニオン性界面活性剤のＨＬＢは、７以上であることが好ましく、８以上であることがより好ましい。また、ノニオン性界面活性剤のＨＬＢは、１８以下であることが好ましく、１７以下であることがより好ましい。ノニオン性界面活性剤のＨＬＢが上記範囲内であることにより、噴霧用組成物は、安息香酸エステルを噴霧用組成物中に可溶化しやすく、均一相を形成しやすい。そのため、噴霧用組成物は、より均一な組成で噴霧されやすい。 HLB of the nonionic surfactant is not particularly limited. As an example, HLB of the nonionic surfactant is preferably 7 or more, and more preferably 8 or more. The HLB of the nonionic surfactant is preferably 18 or less, more preferably 17 or less. When the HLB of the nonionic surfactant is within the above range, the spray composition can easily solubilize the benzoic acid ester in the spray composition and easily form a uniform phase. Therefore, the spraying composition is likely to be sprayed with a more uniform composition.
ノニオン性界面活性剤の含有量は特に限定されない。一例を挙げると、ノニオン性界面活性剤の含有量は、噴霧用組成物中、０．０５質量％以上であることが好ましく、０．１質量％以上であることがより好ましい。また、ノニオン性界面活性剤の含有量は、噴霧用組成物中、１５質量％以下であることが好ましく、１０質量％以下であることがより好ましい。ノニオン性界面活性剤の含有量が上記範囲内であることにより、噴霧用組成物は、より均一な組成を形成しやすい。特に、ノニオン性界面活性剤の含有量（質量％）は、安息香酸エステルの含有量（質量％）の２倍以上となるよう含有されていることが好ましく、２．３倍以上となるよう含有されていることがより好ましい。このような含有量が採用されることにより、噴霧用組成物は、アルコールの含有量が４０質量％以下、好ましくは３５質量％以下である場合であっても、安息香酸エステルを可溶化しやすい。そのため、得られる噴霧用組成物は、火気に対する安全性がより高くなる。 The content of the nonionic surfactant is not particularly limited. As an example, the content of the nonionic surfactant in the composition for spraying is preferably 0.05% by mass or more, and more preferably 0.1% by mass or more. Further, the content of the nonionic surfactant in the composition for spraying is preferably 15% by mass or less, and more preferably 10% by mass or less. When the content of the nonionic surfactant is within the above range, the spraying composition is likely to form a more uniform composition. In particular, the content (% by mass) of the nonionic surfactant is preferably contained so as to be twice or more the content (% by mass) of the benzoic acid ester, and is contained so as to be 2.3 or more times. Is more preferable. By adopting such a content, the spraying composition can easily solubilize the benzoic acid ester even when the alcohol content is 40% by mass or less, preferably 35% by mass or less. .. Therefore, the obtained spray composition has higher safety against fire.
（アルコール）
アルコールは、安息香酸エステルを可溶化し、均一相を形成するために配合される。
(alcohol)
The alcohol is blended to solubilize the benzoate ester and form a homogeneous phase.
アルコールは特に限定されない。一例を挙げると、アルコールは、エタノール、イソプロパノール等の炭素数が２〜３個の１価アルコール等である。 The alcohol is not particularly limited. As an example, the alcohol is a monohydric alcohol having 2 to 3 carbon atoms such as ethanol and isopropanol.
アルコールの含有量は特に限定されない。一例を挙げると、アルコールの含有量は、噴霧用組成物中、０．１質量％以上であることが好ましく、０．５質量％以上であることがより好ましい。また、アルコールの含有量は、噴霧用組成物中、４０質量％以下であることが好ましく、３５質量％以下であることがより好ましい。アルコールの含有量が上記範囲内であることにより、噴霧用組成物は、上記したノニオン性界面活性剤によって均一相が形成されやすい。また、噴霧用組成物は、引火性が低い。そのため、噴霧用組成物は、火気の対する安全性が優れる。また噴射物は、アルコールの気化により安息香酸エステルが分離して下層に移行しやすくなり、床面などで効果を発揮しやすい。 The content of alcohol is not particularly limited. As an example, the content of alcohol in the composition for spraying is preferably 0.1% by mass or more, and more preferably 0.5% by mass or more. Further, the content of alcohol is preferably 40% by mass or less, and more preferably 35% by mass or less in the composition for spraying. When the alcohol content is within the above range, the spraying composition is likely to form a uniform phase by the above-mentioned nonionic surfactant. Moreover, the composition for spraying has low flammability. Therefore, the composition for spraying is excellent in safety against fire. Further, in the propellant, the benzoic acid ester is separated due to the vaporization of alcohol and is easily transferred to the lower layer, so that the propellant is likely to exert its effect on the floor surface.
（水）
水は、噴霧用組成物において上記した安息香酸エステル等を可溶化するための溶媒として、また、噴霧用組成物の火気への安全性を高めるために配合される。
(water)
Water is added as a solvent for solubilizing the above-mentioned benzoic acid ester and the like in the composition for spraying, and for increasing the safety of the spraying composition against fire.
水は特に限定されない。一例を挙げると、水は、精製水、イオン交換水、生理食塩水、滅菌水等である。 Water is not particularly limited. As an example, water is purified water, ion-exchanged water, physiological saline, sterilized water, or the like.
水の含有量は特に限定されない。一例を挙げると、水の含有量は、噴霧用組成物中、５０質量％以上であることが好ましく、６０質量％以上であることがより好ましい。また、水の含有量は、噴霧用組成物中、９９．５質量％以下であることが好ましく、９８質量％以下であることがより好ましい。水の含有量が上記範囲内であることにより、噴霧用組成物は、安息香酸エステル等を可溶化させやすく、かつ、上記したノニオン性界面活性剤によって均一相が形成されやすい。また、噴霧用組成物は、引火性が低くなる。そのため、噴霧用組成物は、安全性が優れる。 The water content is not particularly limited. As an example, the content of water in the composition for spraying is preferably 50% by mass or more, and more preferably 60% by mass or more. Further, the content of water in the composition for spraying is preferably 99.5% by mass or less, and more preferably 98% by mass or less. When the content of water is within the above range, the composition for spraying is likely to solubilize the benzoic acid ester and the like, and the nonionic surfactant described above is likely to form a uniform phase. Also, the composition for spraying has low flammability. Therefore, the composition for spraying is excellent in safety.
（任意成分）
本実施形態の噴霧用組成物は、上記成分以外に、適宜任意成分を含んでもよい。一例を挙げると、任意成分は、水溶性高分子、多価アルコール、有効成分（ただし安息香酸エステルを除く）、油分、粉体等である。
(Arbitrary component)
The composition for spraying of the present embodiment may appropriately contain optional components in addition to the above components. As an example, the optional components are water-soluble polymers, polyhydric alcohols, active ingredients (excluding benzoic acid ester), oils, powders and the like.
・水溶性高分子
水溶性高分子は、噴霧用組成物の粘度等を調整して噴霧粒子の大きさを調整し、使用者の吸入を防止したりするために配合され得る。水溶性高分子は特に限定されない。一例を挙げると、水溶性高分子は、ヒドロキシエチルセルロース、ヒドロキシプロピルセルロース、ヒドロキシプロピルメチルセルロース、カルボキシメチルセルロースナトリウム等のセルロース系多糖類；カラギーナン、キサンタンガム、アラビアゴム、トラガントゴム、カチオン化グアガム、グアガム、ジェランガム、ローカストビーンガム等のガム質；ポリエーテルウレタン、ゼラチン、デキストラン、カルボキシメチルデキストランナトリウム、デキストリン、ペクチン、デンプン、トウモロコシデンプン、コムギデンプン、アルギン酸ナトリウム、変性ポテトスターチ、ヒアルロン酸、ヒアルロン酸ナトリウム、ポリビニルアルコール、ポリビニルピロリドン、カルボキシビニルポリマー等である。
-Water-soluble polymer A water-soluble polymer may be blended to adjust the viscosity of the composition for spraying to adjust the size of the spray particles and prevent inhalation by the user. The water-soluble polymer is not particularly limited. As an example, water-soluble polymers include cellulosic polysaccharides such as hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, sodium carboxymethyl cellulose; carrageenan, xanthan gum, acacia, tragacanth gum, cationized guar gum, guar gum, gellan gum, locust. Gums such as bean gum; polyether urethane, gelatin, dextran, carboxymethyl dextran sodium, dextrin, pectin, starch, corn starch, wheat starch, sodium alginate, modified potato starch, hyaluronic acid, sodium hyaluronate, polyvinyl alcohol, polyvinyl. Examples include pyrrolidone and carboxyvinyl polymer.
水溶性高分子が配合される場合、水溶性高分子の含有量は、噴霧用組成物中、０．０１質量％以上であることが好ましく、０．０２質量％以上であることがより好ましい。また、水溶性高分子の含有量は、噴霧用組成物中、２質量％以下であることが好ましく、１質量％以下であることがより好ましい。水溶性高分子の含有量が上記範囲内であることにより、噴霧用組成物は、適宜に拡がって広範囲に噴霧でき、使用者が吸引することもない。 When the water-soluble polymer is blended, the content of the water-soluble polymer in the composition for spraying is preferably 0.01% by mass or more, and more preferably 0.02% by mass or more. Further, the content of the water-soluble polymer is preferably 2% by mass or less, more preferably 1% by mass or less, in the composition for spraying. When the content of the water-soluble polymer is within the above range, the composition for spraying can be appropriately spread and sprayed in a wide range, and the user does not inhale.
・多価アルコール
多価アルコールは、安息香酸エステルの析出を防止する、引火性を低くして火気への安全性を高くする等の目的で配合され得る。
-Polyhydric alcohol Polyhydric alcohol can be blended for the purpose of preventing the precipitation of benzoic acid ester, lowering the flammability and increasing the safety against fire.
多価アルコールは特に限定されない。一例を挙げると、多価アルコールは、プロピレングリコール、１，３−ブチレングリコール、ヘキシレングリコール、グリセリン、ジプロピレングリコール、ジグリセリン、ソルビトールなどの２〜６価アルコールである。 The polyhydric alcohol is not particularly limited. As an example, the polyhydric alcohol is a dihydric-hydric alcohol such as propylene glycol, 1,3-butylene glycol, hexylene glycol, glycerin, dipropylene glycol, diglycerin or sorbitol.
多価アルコールが配合される場合、多価アルコールの含有量は、噴霧用組成物中、０．１質量％以上であることが好ましく、０．５質量％以上であることがより好ましい。また、多価アルコールの含有量は、噴霧用組成物中、２０質量％以下であることが好ましく、１５質量％以下であることがより好ましい。多価アルコールの含有量が上記範囲内であることにより、噴霧用組成物は、均一相を形成しつつ組成物の引火点を高くして火気への安全性を高くする。 When the polyhydric alcohol is blended, the content of the polyhydric alcohol in the composition for spraying is preferably 0.1% by mass or more, and more preferably 0.5% by mass or more. In addition, the content of the polyhydric alcohol is preferably 20% by mass or less, more preferably 15% by mass or less in the composition for spraying. When the content of the polyhydric alcohol is within the above range, the spraying composition increases the flash point of the composition while forming a homogeneous phase, thereby improving safety against fire.
・有効成分
有効成分は特に限定されない。一例を挙げると、有効成分は、天然香料、合成香料等の各種香料；バラエキス、ユリエキス、ツバキエキス、ユーカリエキス、セージエキス、茶エキス、ローヤルゼリーエキス等の各種抽出液や濃縮したエキス；レチノール、酢酸レチノール、パルミチン酸レチノール、パントテン酸カルシウム、アスコルビン酸ナトリウム、ｄｌ−α−トコフェロール、酢酸トコフェロール、トコフェロール、ニコチン酸トコフェロールおよびこれらの混合物等のビタミン類；アスコルビン酸、α−トコフェロール、ジブチルヒドロキシトルエン、ブチルヒドロキシアニソール等の酸化防止剤；グリシン、アラニン、ロイシン、セリン、トリプトファン、システイン、メチオニン、アスパラギン酸、グルタミン酸、アルギニン等のアミノ酸；安息香酸ナトリウム、ソルビン酸カリウム、フェノキシエタノール、塩化ベンザルコニウム、塩化ベンゼトニウム、塩化クロルヘキシジン、パラクロルメタクレゾール等の殺菌消毒剤；ｌ−メントール、カンフル、ハッカ油等の清涼剤；酸化亜鉛、アラントインヒドロキシアルミニウム、タンニン酸、クエン酸、乳酸等の収斂剤；アラントイン、グリシルレチン酸、グリチルリチン酸ジカリウム、アズレンなどの抗炎症剤；ラウリル酸メタクリレート、フェニル酢酸メチル、ゲラニルクロトレート、ミリスチン酸アセトフェノン、酢酸ベンジル、プロピオン酸ベンジル、緑茶エキス等の消臭剤；ジエチルアミノヒドロキシベンゾイル安息香酸ヘキシル、パラメトキシケイ皮酸２−エチルヘキシル、エチルヘキシルトリアゾン、オキシベンゾン、ヒドロキシベンゾフェノンスルホン酸、ジヒドロキシベンゾフェノンスルホン酸ナトリウム、ジヒドロキシベンゾフェノン等の紫外線吸収剤等である。
-Active ingredient The active ingredient is not particularly limited. As an example, the active ingredients are various flavors such as natural flavors and synthetic flavors; various extracts and concentrated extracts such as rose extract, lily extract, camellia extract, eucalyptus extract, sage extract, tea extract, royal jelly extract; retinol, acetic acid. Vitamin such as retinol, retinol palmitate, calcium pantothenate, sodium ascorbate, dl-α-tocopherol, tocopherol acetate, tocopherol, tocopherol nicotinate and mixtures thereof; ascorbic acid, α-tocopherol, dibutylhydroxytoluene, butylhydroxy Antioxidants such as anisole; amino acids such as glycine, alanine, leucine, serine, tryptophan, cysteine, methionine, aspartic acid, glutamic acid, arginine; sodium benzoate, potassium sorbate, phenoxyethanol, benzalkonium chloride, benzethonium chloride, chloride Disinfectants such as chlorhexidine and parachlormetacresol; cooling agents such as l-menthol, camphor and peppermint oil; astringents such as zinc oxide, allantoin hydroxyaluminum, tannic acid, citric acid and lactic acid; allantoin, glycyrrhetinic acid, glycyrrhizin Anti-inflammatory agents such as dipotassium acid and azulene; deodorants such as lauric acid methacrylate, methyl phenylacetate, geranyl chloride, acetophenone myristate, benzyl acetate, benzyl propionate and green tea extract; hexyl diethylaminohydroxybenzoyl benzoate, paramethoxy UV absorbers such as 2-ethylhexyl cinnamate, ethylhexyltriazone, oxybenzone, hydroxybenzophenone sulfonic acid, sodium dihydroxybenzophenone sulfonate, and dihydroxybenzophenone.
有効成分が配合される場合、有効成分の含有量は、噴霧用組成物中、０．０１質量％以上であることが好ましく、０．１質量％以上であることがより好ましい。また、有効成分の含有量は、噴霧用組成物中、１５質量％以下であることが好ましく、１０質量％以下であることがより好ましい。有効成分の含有量が上記範囲内であることにより、噴霧用組成物は、有効成分を配合することによる効果が得られやすい。 When the active ingredient is blended, the content of the active ingredient in the composition for spraying is preferably 0.01% by mass or more, and more preferably 0.1% by mass or more. The content of the active ingredient in the composition for spraying is preferably 15% by mass or less, more preferably 10% by mass or less. When the content of the active ingredient is within the above range, the composition for spraying can easily obtain the effect by blending the active ingredient.
・油分
油分は、安息香酸エステルの溶媒等として配合され得る。
-Oil component The oil component may be blended as a solvent of benzoic acid ester or the like.
油分は特に限定されない。一例を挙げると、油分は、流動パラフィン、スクワレン、スクワラン、イソパラフィンなどの炭化水素油；アジピン酸ジイソプロピル、ミリスチン酸イソプロピル、パルミチン酸イソプロピル、オクタン酸セチル、ミリスチン酸オクチルドデシル、ステアリン酸ブチル、ミリスチン酸ミリスチル、オレイン酸デシル、乳酸セチル、ステアリン酸イソセチル、セトステアリルアルコール、アジピン酸ジイソブチル、セバシン酸ジイソプロピル、コハク酸ジエトキシエチル、リンゴ酸ジイソステアリル等のエステル油；メチルポリシロキサン、オクタメチルシクロテトラシロキサン、デカメチルシクロペンタシロキサン、ドデカメチルシクロヘキサシロキサン、メチルシクロポリシロキサン、テトラヒドロテトラメチルシクロテトラシロキサン、オクタメチルトリシロキサン、デカメチルテトラシロキサン、メチルハイドロジェンポリシロキサン、メチルフェニルポリシロキサン、ポリグリセロール変性シリコーン等のシリコーンオイル；ラウリルアルコール、ミリスチルアルコール、セチルアルコール、ステアリルアルコール、ベヘニルアルコール、ラノリンアルコール等の高級アルコール；イソステアリン酸等の液体脂肪酸；アボカド油、マカダミアナッツ油、シア脂、オリーブ油、ツバキ油等の油脂；ミツロウ、ラノリンロウ等のロウ類；等である。 The oil content is not particularly limited. For example, the oil is a hydrocarbon oil such as liquid paraffin, squalene, squalane, isoparaffin; diisopropyl adipate, isopropyl myristate, isopropyl palmitate, cetyl octanoate, octyldodecyl myristate, butyl stearate, myristyl myristate. , Ester oils such as decyl oleate, cetyl lactate, isocetyl stearate, cetostearyl alcohol, diisobutyl adipate, diisopropyl sebacate, diethoxyethyl succinate, and diisostearyl malate; methyl polysiloxane, octamethyl cyclotetrasiloxane, Decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, methylcyclopolysiloxane, tetrahydrotetramethylcyclotetrasiloxane, octamethyltrisiloxane, decamethyltetrasiloxane, methylhydrogenpolysiloxane, methylphenylpolysiloxane, polyglycerol-modified silicone, etc. Silicone oils; higher alcohols such as lauryl alcohol, myristyl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, lanolin alcohol; liquid fatty acids such as isostearic acid; oils and fats such as avocado oil, macadamia nut oil, shea butter, olive oil and camellia oil; Waxes such as beeswax and lanolin wax; and the like.
油分が配合される場合、油分の含有量は、噴霧用組成物中、０．０１質量％以上であることが好ましく、０．１質量％以上であることがより好ましい。また、油分の含有量は、噴霧用組成物中、１０質量％以下であることが好ましく、８質量％以下であることがより好ましい。油分の含有量が上記範囲内であることにより、噴霧用組成物は、安息香酸ベンジルとともに油相を形成しやすく、安息香酸ベンジルを配合しやすい。 When the oil component is blended, the content of the oil component in the composition for spraying is preferably 0.01% by mass or more, and more preferably 0.1% by mass or more. Further, the content of the oil component in the composition for spraying is preferably 10% by mass or less, and more preferably 8% by mass or less. When the content of the oil component is within the above range, the spraying composition easily forms an oil phase together with benzyl benzoate, and is easy to incorporate benzyl benzoate.
噴霧用組成物を調製する方法は特に限定されない。一例を挙げると、噴霧用組成物は、アルコールに安息香酸ベンジル、界面活性剤を添加して溶解させ、さらに水を添加して調製する。有効成分、水溶性高分子、多価アルコール、油分等は溶解性に応じて適宜アルコールや水に溶解させる。 The method for preparing the spray composition is not particularly limited. For example, the composition for spraying is prepared by adding benzyl benzoate and a surfactant to alcohol and dissolving them, and further adding water. The active ingredient, water-soluble polymer, polyhydric alcohol, oil and the like are appropriately dissolved in alcohol or water depending on the solubility.
得られた噴霧用組成物は、容器本体内において、均一相を形成する。本実施形態の噴霧用組成物は、２０℃における透過度が５０％以上であることが好ましく、６０％以上であることがより好ましい。なお、本実施形態において、透過度は、たとえば、色彩色差計（ＣＴ−２００、コニカミノルタ（株）製）を使用し、水の透過度を１００％として測定することができる。透過度が上記範囲内であることにより、噴霧用組成物は、温度変化しても組成物の透過度の変化が小さく、より均一な均一相が形成されている。そのため、噴霧用組成物は、より均一な組成で噴霧されやすい。 The resulting spray composition forms a uniform phase within the container body. The spray composition of the present embodiment preferably has a transmittance at 20° C. of 50% or more, more preferably 60% or more. In the present embodiment, the transmittance can be measured by using, for example, a color-difference meter (CT-200, manufactured by Konica Minolta Co., Ltd.) with the transmittance of water being 100%. When the permeability is within the above range, the composition for spraying has a small change in the permeability of the composition even when the temperature changes, and a more uniform homogeneous phase is formed. Therefore, the spraying composition is likely to be sprayed with a more uniform composition.
本実施形態の噴霧用組成物は、たとえば、ポンプ機構により加圧され噴射されるポンプ噴射を行ったり、噴射剤の圧力により噴射されるエアゾール噴射を行うことができる。 The composition for spraying of the present embodiment can perform, for example, pump injection that is pressurized and injected by a pump mechanism or aerosol injection that is injected by the pressure of a propellant.
・ポンプ噴射を行う場合
本実施形態の噴霧用組成物は、開口を有する容器本体に充填される。容器本体の開口にはポンプ機構を有するポンプバルブが取り付けられ、ポンプバルブを操作するための噴射部材が装着されることによりポンプ製品が製造される。噴霧用組成物は、容器本体内からチューブを介してポンプバルブ内に導入され、ポンプ機構により加圧され、噴射部材の噴射孔から霧状に噴射される。なお、ポンプ機構は、蓄圧式でもよく、直圧式でもよい。
-When performing pump injection The spray composition of the present embodiment is filled in a container body having an opening. A pump valve having a pump mechanism is attached to the opening of the container body, and an injection member for operating the pump valve is attached to manufacture a pump product. The spraying composition is introduced into the pump valve from the inside of the container body through the tube, is pressurized by the pump mechanism, and is sprayed in a mist form from the injection hole of the injection member. The pump mechanism may be a pressure accumulation type or a direct pressure type.
・エアゾール噴射を行う場合
本実施形態の噴霧用組成物は、開口を有する耐圧性の容器本体に充填される。容器本体の開口にはエアゾールバルブが取り付けられ、エアゾールバルブから窒素などの噴射剤が充填され、さらに、エアゾールバルブに噴射部材が装着されることによりエアゾール製品が製造される。噴霧用組成物は、容器本体内からチューブを介してエアゾールバルブ内に導入され、噴射剤の圧力により加圧され、噴射部材の噴射孔から霧状に噴射される。
-When performing aerosol injection The spray composition of this embodiment is filled in a pressure-resistant container body having an opening. An aerosol valve is attached to the opening of the container body, a propellant such as nitrogen is filled from the aerosol valve, and an injection member is attached to the aerosol valve to manufacture an aerosol product. The spraying composition is introduced into the aerosol valve through the tube from inside the container body, is pressurized by the pressure of the propellant, and is sprayed in a mist form from the spray holes of the spray member.
噴射剤は特に限定されない。一例を挙げると、噴射剤は、窒素、空気、酸素、水素、二酸化炭素、亜酸化窒素等の圧縮ガスである。これらの中でも、噴射剤は、安定した噴霧状態が得られやすい点から、水に対する溶解性が低い窒素、空気、水素であることが好ましい。なお、容器本体内の圧力は噴射剤により０．２〜１．０ＭＰａに調整されることが好ましい。 The propellant is not particularly limited. By way of example, the propellant is a compressed gas such as nitrogen, air, oxygen, hydrogen, carbon dioxide, nitrous oxide. Among these, the propellant is preferably nitrogen, air, or hydrogen, which has low solubility in water, from the viewpoint that a stable spray state is easily obtained. The pressure inside the container body is preferably adjusted to 0.2 to 1.0 MPa with a propellant.
以下、実施例により本発明をより具体的に説明する。本発明は、これら実施例に何ら限定されない。 Hereinafter, the present invention will be described more specifically with reference to Examples. The present invention is in no way limited to these examples.
（実施例１）
以下の表１に示される処方（単位：質量％）にしたがい、噴霧用組成物を調製し、得られた噴霧用組成物６０ｇを透明なガラス製容器に充填し、キャップを取り付けた。
(Example 1)
A spraying composition was prepared according to the formulation (unit: mass%) shown in Table 1 below, and 60 g of the spraying composition obtained was filled in a transparent glass container and a cap was attached.
（実施例２〜１４、比較例１〜７）
表１〜表２に示される処方に変更した以外は、実施例１と同様の方法により、それぞれの噴霧用組成物を作製した。
(Examples 2 to 14, Comparative Examples 1 to 7)
Each spraying composition was produced by the same method as in Example 1 except that the formulations shown in Tables 1 and 2 were changed.
実施例１〜１４および比較例１〜７の噴霧用組成物に関し、以下の評価方法により、２０℃、５℃および４５℃における外観を評価した。結果を表１〜表２に示す。 With respect to the spray compositions of Examples 1 to 14 and Comparative Examples 1 to 7, the appearance at 20°C, 5°C and 45°C was evaluated by the following evaluation methods. The results are shown in Tables 1 and 2.
＜外観＞
噴霧用組成物を充填したガラス容器を、２０℃、５℃、４５℃に調整された恒温室にて１２時間保管した。恒温室からガラス容器を取り出し、噴霧用組成物の透過度を測定した。
（評価基準）
◎：噴霧用組成物は、透明かつ均一で透過度が８０％以上であった。
○：噴霧用組成物は、半透明かつ均一で透過度が５０〜７９％であった。
×：噴霧用組成物は、白濁し透過度が４９％以下であった。
××：噴霧用組成物は、容器の底部に油滴が沈降した。
<Appearance>
The glass container filled with the composition for spraying was stored for 12 hours in a thermostatic chamber adjusted to 20°C, 5°C, and 45°C. The glass container was taken out from the thermostatic chamber, and the permeability of the spray composition was measured.
(Evaluation criteria)
A: The composition for spraying was transparent and uniform, and the transmittance was 80% or more.
◯: The composition for spraying was semitransparent and uniform, and the transmittance was 50 to 79%.
X: The composition for spraying was cloudy and the transmittance was 49% or less.
XX: In the spray composition, oil droplets settled on the bottom of the container.
＜使用感＞
実施例１〜１４および比較例１〜７の噴霧用組成物１００ｇを、それぞれアルミニウム製耐圧容器に充填し、エアゾールバルブを取り付けた。エアゾールバルブから窒素を充填して容器内の圧力を０．８ＭＰａに調整し、エアゾール製品を製造した。２０℃に調整したエアゾール製品を使って、試験者１０人にカーペットに向かって３秒間噴射してもらい、使用感を評価した。
（評価基準）
〇：１０人全員がむせなかった。
△：噴射開始直後にむせた試験者が１人いた。
×：噴射開始直後にむせた試験者が２人以上いた。
<Usage>
100 g of the spray compositions of Examples 1 to 14 and Comparative Examples 1 to 7 were filled in aluminum pressure-resistant containers, and aerosol valves were attached. Nitrogen was filled from the aerosol valve to adjust the pressure inside the container to 0.8 MPa to manufacture an aerosol product. Using an aerosol product adjusted to 20° C., 10 testers sprayed the carpet for 3 seconds and evaluated the feeling of use.
(Evaluation criteria)
◯: All 10 people could not afford it.
Δ: There was one tester who was put on immediately after the start of injection.
X: There were two or more testers who were put on immediately after the start of injection.
表１または表２に示されるように、本発明の噴霧用組成物は、２０℃だけでなく、５℃および４５℃においても均一であり、温度による変化は小さく、ほとんどが透明であり、安定であった。そのため、このような噴霧用組成物を充填したエアゾール製品は、噴霧用組成物を均一な組成のまま噴霧することができ、試験者はむせなかった。 As shown in Table 1 or Table 2, the spray composition of the present invention is uniform not only at 20° C. but also at 5° C. and 45° C., changes with temperature are small, and most of them are transparent and stable. Met. Therefore, the aerosol product filled with such a spraying composition can spray the spraying composition with a uniform composition, which the tester was not obliged to do.
一方、ノニオン性界面活性剤の中でも特許文献１に記載させているポリオキシエチレンセチルエーテルを使用した比較例１、２の噴霧用組成物は、２０℃では半透明であったが、５℃においては白濁した。また、比較例３、４、６、７の噴霧用組成物は、２０℃、５℃および４５℃のすべての評価温度にて白濁した。アルコールを含んでいない比較例５の噴霧用組成物は、すべての評価温度にて容器の底部に油滴が沈降し、不均一であった。そのため、２０℃で白濁する比較例３、４の噴霧用組成物および不均一な比較例５の噴霧用組成物を充填したエアゾール製品は、噴霧用組成物を均一な組成のまま噴霧することができず、噴射開始直後に試験者がむせやすかった。 On the other hand, among the nonionic surfactants, the spraying compositions of Comparative Examples 1 and 2 using polyoxyethylene cetyl ether described in Patent Document 1 were translucent at 20° C., but at 5° C. Became cloudy. Further, the spray compositions of Comparative Examples 3, 4, 6, and 7 became cloudy at all evaluation temperatures of 20°C, 5°C, and 45°C. The spraying composition of Comparative Example 5 containing no alcohol was non-uniform because oil droplets settled on the bottom of the container at all evaluation temperatures. Therefore, the aerosol product filled with the spray composition of Comparative Examples 3 and 4 which becomes cloudy at 20° C. and the non-uniform spray composition of Comparative Example 5 may spray the spray composition as a uniform composition. It was not possible, and it was easy for the tester to put it immediately after the start of injection.
Claims (7)
均一相を形成する、噴霧用組成物。 Benzoic acid ester, nonionic surfactant, alcohol, and water,
A sprayable composition that forms a homogeneous phase.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE112021003041T5 (en) | 2020-05-29 | 2023-05-04 | Denso Corporation | AIR CONDITIONER |
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