JP2018519513A - 水硬度測定のための較正方法 - Google Patents
水硬度測定のための較正方法 Download PDFInfo
- Publication number
- JP2018519513A JP2018519513A JP2017565974A JP2017565974A JP2018519513A JP 2018519513 A JP2018519513 A JP 2018519513A JP 2017565974 A JP2017565974 A JP 2017565974A JP 2017565974 A JP2017565974 A JP 2017565974A JP 2018519513 A JP2018519513 A JP 2018519513A
- Authority
- JP
- Japan
- Prior art keywords
- ppb
- magnesium
- calibration standard
- standard solution
- soluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims abstract description 83
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 47
- 229910001868 water Inorganic materials 0.000 title claims abstract description 36
- 238000007542 hardness measurement Methods 0.000 title description 5
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 123
- 238000005259 measurement Methods 0.000 claims abstract description 28
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 272
- 239000011777 magnesium Substances 0.000 claims description 272
- 229910052749 magnesium Inorganic materials 0.000 claims description 272
- 239000012086 standard solution Substances 0.000 claims description 244
- 239000003795 chemical substances by application Substances 0.000 claims description 136
- 239000000243 solution Substances 0.000 claims description 99
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 94
- 239000011575 calcium Substances 0.000 claims description 94
- 229910052791 calcium Inorganic materials 0.000 claims description 94
- 150000002681 magnesium compounds Chemical class 0.000 claims description 56
- 230000004044 response Effects 0.000 claims description 53
- 239000000376 reactant Substances 0.000 claims description 51
- 238000002156 mixing Methods 0.000 claims description 35
- 238000011088 calibration curve Methods 0.000 claims description 29
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical group [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 claims description 24
- LGDFHDKSYGVKDC-UHFFFAOYSA-N 8-hydroxyquinoline-5-sulfonic acid Chemical group C1=CN=C2C(O)=CC=C(S(O)(=O)=O)C2=C1 LGDFHDKSYGVKDC-UHFFFAOYSA-N 0.000 claims description 10
- 230000005284 excitation Effects 0.000 claims description 10
- IMNIMPAHZVJRPE-UHFFFAOYSA-N triethylenediamine Chemical compound C1CN2CCN1CC2 IMNIMPAHZVJRPE-UHFFFAOYSA-N 0.000 claims description 8
- -1 1,2-diaminocyclohexanetetraacetic acid disodium salt Chemical class 0.000 claims description 3
- 230000008569 process Effects 0.000 abstract description 5
- 238000011109 contamination Methods 0.000 abstract 1
- 241000894007 species Species 0.000 description 13
- 239000008367 deionised water Substances 0.000 description 11
- 229910021641 deionized water Inorganic materials 0.000 description 11
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 10
- 239000007864 aqueous solution Substances 0.000 description 10
- 150000001875 compounds Chemical class 0.000 description 9
- 239000000203 mixture Substances 0.000 description 9
- 239000012491 analyte Substances 0.000 description 8
- 239000008235 industrial water Substances 0.000 description 8
- 239000012895 dilution Substances 0.000 description 6
- 238000010790 dilution Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 229910000019 calcium carbonate Inorganic materials 0.000 description 5
- 238000004364 calculation method Methods 0.000 description 5
- 238000001917 fluorescence detection Methods 0.000 description 5
- 239000007850 fluorescent dye Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 4
- 239000012973 diazabicyclooctane Substances 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 159000000007 calcium salts Chemical class 0.000 description 3
- 239000013626 chemical specie Substances 0.000 description 3
- 238000012937 correction Methods 0.000 description 3
- 238000007865 diluting Methods 0.000 description 3
- 238000012921 fluorescence analysis Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 238000006467 substitution reaction Methods 0.000 description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 125000003118 aryl group Chemical group 0.000 description 2
- 239000000987 azo dye Substances 0.000 description 2
- 239000001110 calcium chloride Substances 0.000 description 2
- 229910001628 calcium chloride Inorganic materials 0.000 description 2
- ZCCIPPOKBCJFDN-UHFFFAOYSA-N calcium nitrate Chemical compound [Ca+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ZCCIPPOKBCJFDN-UHFFFAOYSA-N 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical class O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 2
- 238000011010 flushing procedure Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 229910001629 magnesium chloride Inorganic materials 0.000 description 2
- YIXJRHPUWRPCBB-UHFFFAOYSA-N magnesium nitrate Chemical compound [Mg+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O YIXJRHPUWRPCBB-UHFFFAOYSA-N 0.000 description 2
- 159000000003 magnesium salts Chemical class 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 150000007530 organic bases Chemical class 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000011002 quantification Methods 0.000 description 2
- 230000025508 response to water Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- UNMYWSMUMWPJLR-UHFFFAOYSA-L Calcium iodide Chemical compound [Ca+2].[I-].[I-] UNMYWSMUMWPJLR-UHFFFAOYSA-L 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 241000212342 Sium Species 0.000 description 1
- MJOQJPYNENPSSS-XQHKEYJVSA-N [(3r,4s,5r,6s)-4,5,6-triacetyloxyoxan-3-yl] acetate Chemical compound CC(=O)O[C@@H]1CO[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O MJOQJPYNENPSSS-XQHKEYJVSA-N 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- VSGNNIFQASZAOI-UHFFFAOYSA-L calcium acetate Chemical compound [Ca+2].CC([O-])=O.CC([O-])=O VSGNNIFQASZAOI-UHFFFAOYSA-L 0.000 description 1
- 239000001639 calcium acetate Substances 0.000 description 1
- 229960005147 calcium acetate Drugs 0.000 description 1
- 235000011092 calcium acetate Nutrition 0.000 description 1
- 229910001622 calcium bromide Inorganic materials 0.000 description 1
- 229940059251 calcium bromide Drugs 0.000 description 1
- YALMXYPQBUJUME-UHFFFAOYSA-L calcium chlorate Chemical compound [Ca+2].[O-]Cl(=O)=O.[O-]Cl(=O)=O YALMXYPQBUJUME-UHFFFAOYSA-L 0.000 description 1
- 229960002713 calcium chloride Drugs 0.000 description 1
- WGEFECGEFUFIQW-UHFFFAOYSA-L calcium dibromide Chemical compound [Ca+2].[Br-].[Br-] WGEFECGEFUFIQW-UHFFFAOYSA-L 0.000 description 1
- 229910001640 calcium iodide Inorganic materials 0.000 description 1
- 229940046413 calcium iodide Drugs 0.000 description 1
- 239000012482 calibration solution Substances 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- SXYCCJAPZKHOLS-UHFFFAOYSA-N chembl2008674 Chemical compound [O-][N+](=O)C1=CC=C2C(N=NC3=C4C=CC=CC4=CC=C3O)=C(O)C=C(S(O)(=O)=O)C2=C1 SXYCCJAPZKHOLS-UHFFFAOYSA-N 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 150000004985 diamines Chemical class 0.000 description 1
- GFVMLYBCWPLMTF-UHFFFAOYSA-N disodiomagnesium Chemical compound [Na][Mg][Na] GFVMLYBCWPLMTF-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 239000012456 homogeneous solution Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- UEGPKNKPLBYCNK-UHFFFAOYSA-L magnesium acetate Chemical compound [Mg+2].CC([O-])=O.CC([O-])=O UEGPKNKPLBYCNK-UHFFFAOYSA-L 0.000 description 1
- 239000011654 magnesium acetate Substances 0.000 description 1
- 235000011285 magnesium acetate Nutrition 0.000 description 1
- 229940069446 magnesium acetate Drugs 0.000 description 1
- OTCKOJUMXQWKQG-UHFFFAOYSA-L magnesium bromide Chemical compound [Mg+2].[Br-].[Br-] OTCKOJUMXQWKQG-UHFFFAOYSA-L 0.000 description 1
- 229910001623 magnesium bromide Inorganic materials 0.000 description 1
- BLQJIBCZHWBKSL-UHFFFAOYSA-L magnesium iodide Chemical compound [Mg+2].[I-].[I-] BLQJIBCZHWBKSL-UHFFFAOYSA-L 0.000 description 1
- 229910001641 magnesium iodide Inorganic materials 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- NNNSKJSUQWKSAM-UHFFFAOYSA-L magnesium;dichlorate Chemical compound [Mg+2].[O-]Cl(=O)=O.[O-]Cl(=O)=O NNNSKJSUQWKSAM-UHFFFAOYSA-L 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 238000010297 mechanical methods and process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- VSQYNPJPULBZKU-UHFFFAOYSA-N mercury xenon Chemical compound [Xe].[Hg] VSQYNPJPULBZKU-UHFFFAOYSA-N 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/18—Water
- G01N33/1853—Hardness of water
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/274—Calibration, base line adjustment, drift correction
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B11/00—Diaryl- or thriarylmethane dyes
- C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
- C09B11/10—Amino derivatives of triarylmethanes
- C09B11/24—Phthaleins containing amino groups ; Phthalanes; Fluoranes; Phthalides; Rhodamine dyes; Phthaleins having heterocyclic aryl rings; Lactone or lactame forms of triarylmethane dyes
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
- C09B67/0071—Process features in the making of dyestuff preparations; Dehydrating agents; Dispersing agents; Dustfree compositions
- C09B67/0083—Solutions of dyes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N21/643—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" non-biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/274—Calibration, base line adjustment, drift correction
- G01N21/278—Constitution of standards
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/12—Circuits of general importance; Signal processing
- G01N2201/127—Calibration; base line adjustment; drift compensation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/18—Water
- G01N33/1813—Specific cations in water, e.g. heavy metals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Optics & Photonics (AREA)
- Molecular Biology (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Tires In General (AREA)
Abstract
【選択図】図1
Description
本特許出願は、その全体が参照により組み込まれる、2015年7月1日に出願された米国特許仮出願第62/187,559号の利益を主張する。
この実施例は、本発明の実施形態による、可溶性マグネシウム及び全硬度を測定するための蛍光測定機の較正方法を例証する。
この実施例は、試料中の可溶性マグネシウム及び全硬度を測定する際の実施例1の自動較正方法の有用性を示す。
Claims (20)
- 可溶性マグネシウム用の蛍光測定機を較正する方法であって、前記方法は:
可溶性マグネシウムを含む低較正標準溶液の背景蛍光を測定することと、
不活性蛍光剤及びマグネシウム配位性蛍光試薬を含むマグネシウム反応剤溶液を、前記低較正標準溶液と混合し、それにより、前記不活性蛍光剤及び配位されたマグネシウム化合物を含む、混合された低較正標準溶液を形成することと、
前記混合された低較正標準溶液における前記不活性蛍光剤及び前記配位されたマグネシウム化合物の蛍光応答を測定することと、
可溶性マグネシウム及び不活性蛍光剤を含む高較正標準溶液における不活性蛍光剤の蛍光応答を測定することと、
マグネシウム反応剤溶液を前記高較正標準溶液と混合し、それにより、不活性蛍光剤及び配位されたマグネシウム化合物を含む、混合された高較正標準溶液を形成することと、
前記混合された高較正標準溶液における前記不活性蛍光剤及び前記配位されたマグネシウム化合物の蛍光応答を測定することと、
前記測定された蛍光応答、ならびに前記低較正標準溶液中、及び前記高較正標準溶液中の可溶性マグネシウム及び不活性蛍光剤の既知の濃度に基づき、前記蛍光測定機を較正することと、を含む、方法。 - 前記測定された蛍光応答と、前記低較正標準溶液中、及び前記高較正標準溶液中の可溶性マグネシウム及び不活性蛍光剤の既知の濃度と、に基づき、マグネシウム及び不活性蛍光剤についての較正曲線をプロットすることによって、前記蛍光測定機が較正され、前記較正曲線が、前記蛍光測定機を較正するのに使用される、請求項1に記載の方法。
- 前記較正曲線の方程式が制御装置によって格納され、前記方程式が前記蛍光測定機を自動的に較正するのに使用される、請求項2に記載の方法。
- 前記蛍光測定機が、各測定ステップの前に、前記低較正標準溶液または前記高較正標準溶液でフラッシングされる、請求項1〜3のいずれか一項に記載の方法。
- 前記低較正標準溶液が、約0ppb〜約200ppbの濃度の可溶性マグネシウムを含み、前記高較正標準溶液が、約50ppb〜約900ppbの濃度の可溶性マグネシウム、及び約1ppb〜約20ppbの濃度の前記不活性蛍光剤を含む、請求項1〜4のいずれか一項に記載の方法。
- 前記不活性蛍光剤が、ローダミンWTである、請求項1〜5のいずれか一項に記載の方法。
- 前記マグネシウム配位性蛍光試薬が、8‐ヒドロキシキノリン‐5‐スルホン酸である、請求項1〜6のいずれか一項に記載の方法。
- 可溶性マグネシウム及び全硬度用の蛍光測定機を較正する方法であって、前記方法は:
可溶性マグネシウム及び可溶性カルシウムを含む低較正標準溶液の背景蛍光を測定することと、
不活性蛍光剤及びマグネシウム配位性蛍光試薬を含むマグネシウム反応剤溶液を、前記低較正標準溶液と混合し、それにより、前記不活性蛍光剤及び配位されたマグネシウム化合物を含む、混合された低較正標準溶液を形成することと、
前記混合された低較正標準溶液における前記不活性蛍光剤及び前記配位されたマグネシウム化合物の蛍光応答を測定することと、
前記マグネシウム反応剤溶液と、マグネシウム含有試薬を含む全硬度反応剤溶液とを、前記低較正標準溶液と混合し、それにより、前記不活性蛍光剤及び前記配位されたマグネシウム化合物を含む、カルシウム置換低較正標準溶液を形成することと、
前記カルシウム置換低較正標準溶液における前記不活性蛍光剤及び前記配位されたマグネシウム化合物の蛍光応答を測定することと、
可溶性マグネシウム、可溶性カルシウム、及び前記不活性蛍光剤を含む高較正標準溶液における前記不活性蛍光剤の蛍光応答を測定することと、
前記マグネシウム反応剤溶液を、前記高較正標準溶液と混合し、それにより、前記不活性蛍光剤及び前記配位されたマグネシウム化合物を含む、混合された高較正標準溶液を形成することと、
前記混合された高較正標準溶液における前記不活性蛍光剤及び前記配位されたマグネシウム化合物の蛍光応答を測定することと、
前記マグネシウム反応剤溶液及び前記全硬度反応剤溶液を、前記高較正標準溶液と混合し、それにより、前記不活性蛍光剤及び前記配位されたマグネシウム化合物を含む、カルシウム置換高較正標準溶液を形成することと、
前記カルシウム置換高較正標準溶液における前記不活性蛍光剤及び前記配位されたマグネシウム化合物の蛍光応答を測定することと、
前記測定された蛍光応答、ならびに前記低較正標準溶液中、及び前記高較正標準溶液中の可溶性マグネシウム、可溶性カルシウム、及び不活性蛍光剤の既知の濃度に基づき、前記蛍光測定機を較正することと、を含む、方法。 - 前記測定された蛍光応答と、前記低較正標準溶液中、及び前記高較正標準溶液中の可溶性マグネシウム、可溶性カルシウム、及び不活性蛍光剤の既知の濃度と、に基づき、可溶性マグネシウム、前記全硬度、及び前記不活性蛍光剤についての較正曲線をプロットし、前記較正曲線によって、前記蛍光測定機が較正される、請求項8に記載の方法。
- 前記較正曲線の方程式が制御装置によって格納され、前記方程式が前記蛍光測定機を自動的に較正するのに使用される、請求項9に記載の方法。
- 前記蛍光測定機が、各測定ステップの前に、前記低較正標準溶液または前記高較正標準溶液でフラッシングされる、請求項8〜10のいずれか一項に記載の方法。
- 前記低較正標準溶液が、約0ppb〜約200ppbの濃度の可溶性マグネシウム、及び約0ppb〜約200ppbの濃度の可溶性カルシウムを含み、前記高較正標準溶液が、約50ppb〜約900ppbの濃度の可溶性マグネシウム、約50ppb〜約900ppbの濃度の可溶性カルシウム、及び約1ppb〜約20ppbの濃度の前記不活性蛍光剤を含む、請求項8〜11のいずれか一項に記載の方法。
- 前記不活性蛍光剤が、ローダミンWTである、請求項8〜12のいずれか一項に記載の方法。
- 前記マグネシウム配位性蛍光試薬が、8‐ヒドロキシキノリン‐5‐スルホン酸である、請求項8〜13のいずれか一項に記載の方法。
- 前記マグネシウム含有試薬が、マグネシウム(1,2‐ジアミノシクロヘキサン四酢酸二ナトリウム塩)である、請求項8〜14のいずれか一項に記載の方法。
- 水、
約0ppb〜約200ppbの濃度の可溶性マグネシウム、及び
約0ppb〜約200ppbの濃度の可溶性カルシウム、を含む、第1の較正標準溶液と、
水、
約50ppb〜約900ppbの濃度の可溶性マグネシウム、
約50ppb〜約900ppbの濃度の可溶性カルシウム、及び
約210nm〜約830nmの波長を有する励起光に対して蛍光応答を提供することができる、約1ppb〜約20ppbの不活性蛍光剤、を含む、第2の較正標準溶液と、を備える、較正標準溶液。 - 前記第1及び第2の較正標準溶液のそれぞれにおける可溶性マグネシウムの前記濃度及び可溶性カルシウムの前記濃度が、重量対重量基準でほぼ同じである、請求項16に記載の較正標準溶液。
- 前記第1及び第2の較正標準溶液のそれぞれにおける前記不活性蛍光剤が、約450nm〜約750nmの波長を有する励起光に対して蛍光応答を提供することができる、請求項16または17に記載の較正標準溶液。
- 前記第1及び第2の較正標準溶液のそれぞれにおける前記不活性蛍光剤が、ローダミンWTである、請求項16〜18のいずれか一項に記載の較正標準溶液。
- 前記第1の較正標準溶液及び前記第2の較正標準溶液のそれぞれが、1,4‐ジアザビシクロ[2.2.2]オクタンをさらに含む、請求項16〜19のいずれか一項に記載の較正標準溶液。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562187559P | 2015-07-01 | 2015-07-01 | |
US62/187,559 | 2015-07-01 | ||
PCT/US2016/040751 WO2017004553A1 (en) | 2015-07-01 | 2016-07-01 | Calibration method for water hardness measurement |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2018519513A true JP2018519513A (ja) | 2018-07-19 |
JP6773692B2 JP6773692B2 (ja) | 2020-10-21 |
Family
ID=56611558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017565974A Active JP6773692B2 (ja) | 2015-07-01 | 2016-07-01 | 水硬度測定のための較正方法 |
Country Status (10)
Country | Link |
---|---|
US (1) | US10317385B2 (ja) |
EP (2) | EP4224144A1 (ja) |
JP (1) | JP6773692B2 (ja) |
CN (1) | CN107771279B (ja) |
AU (1) | AU2016288252B2 (ja) |
BR (1) | BR112017026865B1 (ja) |
CA (1) | CA2989956C (ja) |
ES (1) | ES2953378T3 (ja) |
MX (1) | MX2017016861A (ja) |
WO (1) | WO2017004553A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2020115089A (ja) * | 2019-01-17 | 2020-07-30 | 国立大学法人大阪大学 | 水の硬度の測定 |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2019226561A1 (en) * | 2018-03-02 | 2020-09-17 | Ecolab Usa Inc. | Ultralow range fluorometer calibration |
US11759752B2 (en) | 2018-12-21 | 2023-09-19 | Ecolab Usa Inc. | Quick tracer injection for monitoring osmosis membrane integrity |
US11162933B2 (en) * | 2019-09-11 | 2021-11-02 | Haier Us Appliance Solutions, Inc. | System and method for detecting heavy metals in a fluid |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0572131A (ja) * | 1991-09-18 | 1993-03-23 | Kurita Water Ind Ltd | アゾール類の濃度管理方法 |
JPH11190728A (ja) * | 1997-12-26 | 1999-07-13 | Fuji Electric Co Ltd | マグネシウムイオン濃度測定装置 |
WO2006016564A1 (ja) * | 2004-08-11 | 2006-02-16 | Miz Co., Ltd. | 電解機能水生成装置における性能維持方法 |
US20140273243A1 (en) * | 2013-03-14 | 2014-09-18 | Ecolab Usa Inc. | Water hardness monitoring via fluorescence |
Family Cites Families (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3960497A (en) | 1975-08-19 | 1976-06-01 | Beckman Instruments, Inc. | Chemical analyzer with automatic calibration |
US4355072A (en) | 1980-02-12 | 1982-10-19 | U.S. Philips Corporation | Magnetic hexagonal ferrite layer on a nonmagnetic hexagonal mixed crystal substrate |
US4383043A (en) | 1981-07-13 | 1983-05-10 | American Monitor Corporation | Magnesium assay with calmagite or eriochrome black T reagents |
US4457847B2 (en) | 1981-11-05 | 1996-12-31 | Nalco Chemical Co | Carboxylate polymers for internal scale control agents in boiler systems |
US4545920A (en) | 1982-05-28 | 1985-10-08 | Nalco Chemical Company | Boiler water treating compositions |
US4999305A (en) | 1985-07-10 | 1991-03-12 | Wolcott Duane K | Apparatus for titration flow injection analysis |
US4711726A (en) | 1986-12-29 | 1987-12-08 | Nalco Chemical Company | Carboxylate N-vinylamide copolymers for internal scale control and passivation in high pressure boiler systems |
US5173434A (en) | 1990-11-05 | 1992-12-22 | Baxter Diagnostics Inc. | Measurement of color reactions by monitoring a change of fluorescence |
US5041386A (en) | 1988-12-19 | 1991-08-20 | Nalco Chemical Company | Concentration cycles, percent life holding time and continuous treatment concentration monitoring in boiler systems by inert tracers |
DE69032422T2 (de) | 1989-12-15 | 1999-02-04 | Hoffmann La Roche | Reagenzzusammensetzung, Verfahren und Kits zur Quantifizierung von Magnesium oder Calcium und Magnesium |
US5094958A (en) | 1990-08-30 | 1992-03-10 | Fiberchem Inc. | Method of self-compensating a fiber optic chemical sensor |
US5302253A (en) | 1992-04-13 | 1994-04-12 | Nalco Chemical Company | On-line acid monitor and neutralizer feed control of the overhead water in oil refineries |
US5324665A (en) | 1992-11-18 | 1994-06-28 | Nalco Chemical Company | On-line method for monitoring chloride levels in a fluid stream |
US5425267A (en) | 1993-08-31 | 1995-06-20 | Nalco Chemical Company | Corrosion simulator and method for simulating corrosion activity of a process stream |
US5462880A (en) | 1993-09-13 | 1995-10-31 | Optical Sensors Incorporated | Ratiometric fluorescence method to measure oxygen |
US5384050A (en) | 1993-11-04 | 1995-01-24 | Nalco Chemical Company | Hydrazones as oxygen scavengers in boiler water systems |
US5411889A (en) * | 1994-02-14 | 1995-05-02 | Nalco Chemical Company | Regulating water treatment agent dosage based on operational system stresses |
US5672515A (en) | 1995-09-12 | 1997-09-30 | Optical Sensors Incorporated | Simultaneous dual excitation/single emission fluorescent sensing method for PH and pCO2 |
US5736405A (en) * | 1996-03-21 | 1998-04-07 | Nalco Chemical Company | Monitoring boiler internal treatment with fluorescent-tagged polymers |
US5734098A (en) | 1996-03-25 | 1998-03-31 | Nalco/Exxon Energy Chemicals, L.P. | Method to monitor and control chemical treatment of petroleum, petrochemical and processes with on-line quartz crystal microbalance sensors |
US6336058B1 (en) | 2000-05-01 | 2002-01-01 | Nalco Chemical Company | Use of control matrix for boiler control |
US6587753B2 (en) | 2000-05-01 | 2003-07-01 | Ondeo Nalco Company | Use of control matrix for boiler control |
US6735535B1 (en) | 2000-05-05 | 2004-05-11 | Electro Industries/Gauge Tech. | Power meter having an auto-calibration feature and data acquisition capabilities |
US6436711B1 (en) | 2000-12-13 | 2002-08-20 | Nalco Chemical Company | Fluorometric control of aromatic oxygen scavengers in a boiler system |
US6790666B2 (en) * | 2001-12-28 | 2004-09-14 | Nalco Company | Method to ascertain whether soluble hardness is calcium or magnesium based |
US6790664B2 (en) | 2001-12-28 | 2004-09-14 | Nalco Company | Fluorometric monitoring and control of soluble hardness of water used in industrial water systems |
US7220382B2 (en) | 2003-07-31 | 2007-05-22 | Nalco Company | Use of disulfonated anthracenes as inert fluorescent tracers |
CA2577340A1 (en) | 2004-08-19 | 2006-03-02 | Blood Cell Storage, Inc. | Fluorescent ph detector system and related methods |
US20060246595A1 (en) | 2005-05-02 | 2006-11-02 | Banks Rodney H | Method for using an all solid-state fluorometer in monitoring and controlling chemicals in water |
AU2006306384B2 (en) | 2005-10-26 | 2012-06-14 | General Electric Company | Methods and systems for delivery of fluidic samples to sensor arrays |
US7402424B2 (en) | 2006-02-01 | 2008-07-22 | Schlumberger Technology Corporation | Spectroscopic pH measurement at high-temperature and/or high-pressure |
US8147758B2 (en) * | 2006-06-23 | 2012-04-03 | General Electric Company | Water hardness sensor system |
US7448255B2 (en) | 2006-06-29 | 2008-11-11 | Nalco Company | Very high-temperature fluorescent tracer and automation for boiler water applications |
CN101210930A (zh) * | 2006-12-27 | 2008-07-02 | 中国科学院沈阳应用生态研究所 | 一种测定血清中镁含量的方法 |
US8658094B2 (en) | 2007-01-29 | 2014-02-25 | Nalco Company | High temperature and pressure oxidation-reduction potential measuring and monitoring device for hot water systems |
US8658095B2 (en) | 2007-01-29 | 2014-02-25 | Nalco Company | High temperature and pressure oxidation-reduction potential measuring and monitoring device for hot water systems |
US7951298B2 (en) | 2007-09-10 | 2011-05-31 | Nalco Company | Method and device for preventing corrosion in hot water systems undergoing intermittent operations |
US7955853B2 (en) | 2007-07-24 | 2011-06-07 | Nalco Company | Method and device for creating and analyzing an at temerature and pressure oxidation-reduction potential signature in hot water systems for preventing corrosion |
WO2009067626A1 (en) | 2007-11-21 | 2009-05-28 | Glumetrics, Inc. | Use of an equilibrium intravascular sensor to achieve tight glycemic control |
US8068033B2 (en) | 2008-10-31 | 2011-11-29 | Nalco Company | Method of detecting contamination in industrial process boiler systems |
US9150793B2 (en) | 2008-11-03 | 2015-10-06 | Nalco Company | Method of reducing corrosion and corrosion byproduct deposition in a crude unit |
US8352207B2 (en) * | 2010-03-31 | 2013-01-08 | Ecolab Usa Inc. | Methods for calibrating a fluorometer |
US8951472B2 (en) * | 2010-07-19 | 2015-02-10 | Andalyze, Inc. | Portable fluorimetric apparatus, method and system |
US9134238B2 (en) | 2010-12-01 | 2015-09-15 | Nalco Company | Method for determination of system parameters for reducing crude unit corrosion |
EP2657681A1 (en) * | 2012-04-26 | 2013-10-30 | Roche Diagnostics GmbH | Improvement of the sensitivity and the dynamic range of photometric assays by generating multiple calibration curves |
BR112016004947B1 (pt) * | 2013-09-13 | 2021-10-19 | Ecolab Usa Inc | Método para analisar uma ou mais propriedades de uma alíquota de água, e, embalagem |
-
2016
- 2016-07-01 BR BR112017026865-5A patent/BR112017026865B1/pt active IP Right Grant
- 2016-07-01 ES ES16748181T patent/ES2953378T3/es active Active
- 2016-07-01 EP EP23179145.0A patent/EP4224144A1/en active Pending
- 2016-07-01 EP EP16748181.1A patent/EP3317644B1/en active Active
- 2016-07-01 WO PCT/US2016/040751 patent/WO2017004553A1/en active Application Filing
- 2016-07-01 CN CN201680036322.9A patent/CN107771279B/zh active Active
- 2016-07-01 AU AU2016288252A patent/AU2016288252B2/en active Active
- 2016-07-01 MX MX2017016861A patent/MX2017016861A/es unknown
- 2016-07-01 JP JP2017565974A patent/JP6773692B2/ja active Active
- 2016-07-01 US US15/200,728 patent/US10317385B2/en active Active
- 2016-07-01 CA CA2989956A patent/CA2989956C/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0572131A (ja) * | 1991-09-18 | 1993-03-23 | Kurita Water Ind Ltd | アゾール類の濃度管理方法 |
JPH11190728A (ja) * | 1997-12-26 | 1999-07-13 | Fuji Electric Co Ltd | マグネシウムイオン濃度測定装置 |
WO2006016564A1 (ja) * | 2004-08-11 | 2006-02-16 | Miz Co., Ltd. | 電解機能水生成装置における性能維持方法 |
EP1803687A1 (en) * | 2004-08-11 | 2007-07-04 | MIZ Co., Ltd. | Performance maintaining method in electrolysis functional water producing device |
US20080302651A1 (en) * | 2004-08-11 | 2008-12-11 | Miz Co., Ltd. | Performance Maintaining Method For Electrolyzed Functional Water Generating Apparatus |
JP2010162544A (ja) * | 2004-08-11 | 2010-07-29 | Mizu Kk | 電解機能水生成装置における性能維持方法 |
US20140273243A1 (en) * | 2013-03-14 | 2014-09-18 | Ecolab Usa Inc. | Water hardness monitoring via fluorescence |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2020115089A (ja) * | 2019-01-17 | 2020-07-30 | 国立大学法人大阪大学 | 水の硬度の測定 |
JP7148136B2 (ja) | 2019-01-17 | 2022-10-05 | 国立大学法人大阪大学 | 水の硬度の測定 |
Also Published As
Publication number | Publication date |
---|---|
BR112017026865B1 (pt) | 2021-08-31 |
US10317385B2 (en) | 2019-06-11 |
US20170003261A1 (en) | 2017-01-05 |
EP3317644C0 (en) | 2023-07-19 |
WO2017004553A1 (en) | 2017-01-05 |
JP6773692B2 (ja) | 2020-10-21 |
BR112017026865A2 (pt) | 2020-06-30 |
CN107771279B (zh) | 2022-03-22 |
EP4224144A1 (en) | 2023-08-09 |
EP3317644A1 (en) | 2018-05-09 |
CA2989956C (en) | 2024-05-14 |
AU2016288252B2 (en) | 2021-08-12 |
AU2016288252A1 (en) | 2017-12-21 |
CA2989956A1 (en) | 2017-01-05 |
MX2017016861A (es) | 2018-04-10 |
CN107771279A (zh) | 2018-03-06 |
EP3317644B1 (en) | 2023-07-19 |
ES2953378T3 (es) | 2023-11-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2018233043B2 (en) | Water hardness monitoring via fluorescence | |
JP2018519513A (ja) | 水硬度測定のための較正方法 | |
RU2013124969A (ru) | Способ и устройство для определения параметров системы в целях уменьшения коррозии в установке первичной обработки нефти | |
RU2013124970A (ru) | Способ и устройство для определения параметров системы в целях уменьшения коррозии в установке первичной обработки нефти | |
WO2012016350A1 (en) | Simultaneous determination of multiple analytes in industrial water system | |
JP2009085943A (ja) | Icp発光分光分析方法 | |
CN108137635B (zh) | 乙酸盐络合物和用于乙酸盐定量的方法 | |
CN100368807C (zh) | 水中微量成分的测定方法和装置 | |
JP2005099014A (ja) | リン酸測定方法とその装置 | |
US12019021B2 (en) | Zinc measurement | |
US20210372924A1 (en) | Zinc measurement | |
US10677717B2 (en) | Colorimetric analyzer with reagent diagnostics | |
JP2005265474A (ja) | フッ化物イオンの定量方法 | |
WO2024118716A1 (en) | Indigo-based indicator detection of ozone |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20190605 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20200129 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20200204 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20200430 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20200901 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20201001 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6773692 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |