JP2018103087A - Kneader - Google Patents

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JP2018103087A
JP2018103087A JP2016250512A JP2016250512A JP2018103087A JP 2018103087 A JP2018103087 A JP 2018103087A JP 2016250512 A JP2016250512 A JP 2016250512A JP 2016250512 A JP2016250512 A JP 2016250512A JP 2018103087 A JP2018103087 A JP 2018103087A
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container
kneading
holder
container holder
revolution
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JP6633506B2 (en
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明 荒木
Akira Araki
明 荒木
井上　正
Tadashi Inoue
正 井上
幸一 長井
Koichi Nagai
幸一 長井
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DAIDO KAKO KK
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Abstract

PROBLEM TO BE SOLVED: To provide a kneader capable of properly kneading a kneading object material by autorotation-revolution, while attaining simplification of a structure, reduction in cost and facilitation of attachment-detachment of a kneading container.SOLUTION: In a kneader having an autorotation container holder 21 for detachably storing a kneading container in a rotary body 12 capable of driving-rotating around the revolution axis Y1 linked to revolution driving means 11 and provided with autorotation driving means 30 for driving-rotating the container holder 21 around the autorotation axis Y2, accommodation for allowing the movement in the radial direction of the kneading container to the container holder 21, is provided between an inner surface of the container holder 21 and an outer surface of the kneading container, and a revolution rotational speed of the container holder 21 by the revolution driving means 11 is set to a revolution rotational speed for making the kneading container autorotate by frictional force between the outer surface of the pressed kneading container and the inner surface of the container holder 21, by pressing the outer surface of the kneading container to the inner surface of the container holder 21 by centrifugal force in revolution rotational time.SELECTED DRAWING: Figure 1

Description

本発明は、軟膏、半田ペースト、油脂、染料等の流動性のある被混練材料を公転と自転とによって混練する混練装置で、詳しくは、公転駆動手段に連動された公転軸芯周りで駆動回転可能な回転体に、混練容器を脱着自在に収納する自転自在な容器ホルダが備えられ、前記容器ホルダを自転軸芯周りで駆動回転させる自転駆動手段が設けられている混練装置に関する。   The present invention relates to a kneading apparatus for kneading a fluid material to be kneaded such as ointment, solder paste, fats and oils by revolution and rotation, and more specifically, driving and rotating around a revolution axis linked to revolution drive means. The present invention relates to a kneading apparatus in which a rotatable body is provided with a rotatable container holder that detachably accommodates a kneading container, and provided with a rotation driving means for driving and rotating the container holder around a rotation axis.

上述の混練装置において、例えば、特許文献１では、容器ホルダの内径を混練容器の外径に近い大きさに構成し、容器ホルダ内に混練容器をガタツキの無い略密着状態で装着保持する構成が開示されている。しかし、容器ホルダに装着される混練容器は、混練装置を使用するメーカーによって異なり、少なくとも外径の異なる複数種類の蓋付き混練容器が使用されている。
そのため、特許文献１に示す混練装置においては、蓋付き混練容器の種類に応じた内径の複数種類の容器ホルダを準備するか、若しくは、容器ホルダの内径と混練容器の外径の差を吸収するアダプタを混練容器の種類数だけ準備する必要があり、混練装置のコストが高騰化する問題がある。 In the above-described kneading apparatus, for example, Patent Document 1 has a configuration in which the inner diameter of the container holder is configured to be close to the outer diameter of the kneading container, and the kneading container is mounted and held in the container holder in a substantially intimate contact state. It is disclosed. However, the kneading container mounted on the container holder differs depending on the manufacturer using the kneading apparatus, and at least a plurality of types of kneading containers with lids having different outer diameters are used.
Therefore, in the kneading apparatus shown in Patent Document 1, a plurality of types of container holders having an inner diameter corresponding to the type of kneading container with a lid are prepared, or the difference between the inner diameter of the container holder and the outer diameter of the kneading container is absorbed. It is necessary to prepare as many adapters as the number of types of kneading containers, which raises a problem of increasing the cost of the kneading apparatus.

そこで、特許文献２の混練装置では、容器ホルダの内径を混練容器の外径よりも大きく構成し、この容器ホルダの底部には、外径の異なる複数種類の混練容器をそれの中心が自転軸芯上に位置する状態で各混練容器の下端部の周方向複数個所を径方向から挾持する容器保持固定手段が設けられている。さらに、容器ホルダの蓋体には、公転に伴う径方向外方に向かう遠心力の作用によって、混練容器を容器ホルダの底壁に押圧する押圧手段が、容器ホルダに対して自転軸芯方向に移動可能に設けられている。   Therefore, in the kneading apparatus of Patent Document 2, the inner diameter of the container holder is configured to be larger than the outer diameter of the kneading container, and a plurality of types of kneading containers having different outer diameters are arranged at the center of the rotating shaft at the bottom of the container holder. Container holding and fixing means is provided for holding a plurality of circumferential positions at the lower end of each kneading container from the radial direction while being positioned on the core. Furthermore, the lid of the container holder has a pressing means for pressing the kneading container against the bottom wall of the container holder in the direction of the axis of rotation with respect to the container holder by the action of a centrifugal force directed radially outward accompanying the revolution. It is provided to be movable.

特開２００９−１１９５８８号公報JP 2009-119588 A 特開２０１６−０９７３７２号公報JP, 2006-097372, A

上述の特許文献２の混練装置では、混練容器の種類に応じた内径の複数種類の容器ホルダ又はアダプタを製作する必要がないものの、容器ホルダの底部及び蓋体に容器保持固定手段及び押圧手段を組付けなければならず、構造の複雑化とコストの高騰化を招来するとともに、混練容器の脱着操作に手間が掛かる不都合がある。   In the above-described kneading apparatus of Patent Document 2, although it is not necessary to manufacture a plurality of types of container holders or adapters having an inner diameter corresponding to the type of the kneading container, the container holding and fixing means and the pressing means are provided on the bottom and lid of the container holder. As a result, the structure is complicated and the cost is increased, and the kneading container is not easily attached and detached.

この実情に鑑み、本発明の主たる課題は、構造の簡素化とコストの低廉化及び混練容器の脱着操作の容易化を図りながら、被混練材料を公転と自転とによって適切に混練することのできる混練装置を提供する点にある。   In view of this situation, the main problem of the present invention is that the material to be kneaded can be appropriately kneaded by revolution and rotation while simplifying the structure, reducing the cost, and facilitating the detaching operation of the kneading container. It is in providing a kneading apparatus.

本発明による第１の特徴構成は、公転駆動手段に連動された公転軸芯周りで駆動回転可能な回転体に、混練容器を脱着自在に収納する自転自在な容器ホルダが備えられ、前記容器ホルダを自転軸芯周りで駆動回転させる自転駆動手段が設けられている混練装置であって、
前記容器ホルダの内面と前記混練容器の外面との間に、前記容器ホルダに対する前記混練容器の径方向への移動を許容する融通を設け、前記公転駆動手段による前記容器ホルダの公転回転速度を、公転回転時の遠心力で前記混練容器の外面が前記容器ホルダの内面に押し付けられ、且つ、その押し付けられた前記混練容器の外面と前記容器ホルダの内面との間での摩擦力で前記混練容器が自転する公転回転速度に設定してある点にある。 According to a first characteristic configuration of the present invention, there is provided a self-rotating container holder for detachably storing a kneading container in a rotating body that can be driven and rotated around a revolution axis linked to a revolution driving means, and the container holder A kneading apparatus provided with a rotation driving means for driving and rotating the rotation around the rotation axis,
Provided between the inner surface of the container holder and the outer surface of the kneading container to allow the kneading container to move in the radial direction with respect to the container holder, and the revolution speed of the container holder by the revolution driving means, The outer surface of the kneading container is pressed against the inner surface of the container holder by centrifugal force during revolution rotation, and the kneading container is subjected to a frictional force between the pressed outer surface of the kneading container and the inner surface of the container holder. Is set to the revolution speed of rotation.

上記構成によれば、容器ホルダの内面と前記混練容器の外面との間に設けられた融通により、容器ホルダに対する混練容器の脱着操作を容易に行うことができる。しかも、このような融通を設けていても、公転駆動手段によって容器ホルダが公転軸芯周りで駆動回転されると、公転回転時の遠心力により、混練容器が容器ホルダの径方向に移動し、混練容器の外面が容器ホルダの内面に押し付けられる。このとき、自転駆動手段によって容器ホルダが自転軸芯周りで駆動回転されているので、混練容器の外面と容器ホルダの内面との間での摩擦力により、混練容器が容器ホルダと一体的に自転する。
混練容器の中心が容器ホルダの自転軸芯から位置ずれしても、自転によって混練容器に加わる遠心力は、混練容器の重量（質量）、自転角速度、混練容器の半径との関係で決まるため、混練容器の自転軸芯からの位置変動による影響はない。 According to the said structure, the attachment / detachment operation of the kneading | mixing container with respect to a container holder can be easily performed by the accommodation provided between the inner surface of the container holder and the outer surface of the said kneading | mixing container. Moreover, even if such flexibility is provided, when the container holder is driven and rotated around the revolution axis by the revolution driving means, the kneading container moves in the radial direction of the container holder due to the centrifugal force during the revolution rotation, The outer surface of the kneading container is pressed against the inner surface of the container holder. At this time, since the container holder is driven and rotated around the rotation axis by the rotation driving means, the kneading container is rotated integrally with the container holder by the frictional force between the outer surface of the kneading container and the inner surface of the container holder. To do.
Even if the center of the kneading container is displaced from the rotation axis of the container holder, the centrifugal force applied to the kneading container by rotation is determined by the relationship between the weight (mass) of the kneading container, the rotation angular velocity, and the radius of the kneading container. There is no influence by the position fluctuation from the rotation axis of the kneading container.

それ故に、混練容器をそれの中心が自転軸芯上に位置する状態で当該混練容器の下端部の周方向複数個所を径方向から挾持する容器保持固定手段、混練容器を容器ホルダの底壁に押圧する押圧手段等を設ける必要がなく、また、混練容器の種類に応じた内径の複数種類の容器ホルダ又はアダプタを製作する必要もない。
したがって、構造の簡素化とコストの低廉化及び混練容器の脱着操作の容易化を図りながら、被混練材料を公転と自転とによって適切に混練することができる。 Therefore, container holding and fixing means for holding the kneading container from the radial direction at a plurality of circumferential positions at the lower end of the kneading container in a state where the center of the kneading container is located on the rotation axis, and the kneading container on the bottom wall of the container holder. There is no need to provide pressing means or the like for pressing, and it is not necessary to manufacture a plurality of types of container holders or adapters having an inner diameter corresponding to the type of kneading container.
Therefore, the material to be kneaded can be appropriately kneaded by revolution and rotation while simplifying the structure, reducing the cost, and facilitating the detaching operation of the kneading container.

本発明による第２の特徴構成は、前記容器ホルダは、前記回転体に設けられた容器ホルダ保持部に対して脱着自在に構成されている点にある。   A second characteristic configuration according to the present invention is that the container holder is configured to be detachable with respect to a container holder holding portion provided in the rotating body.

上記構成によれば、回転体の容器ホルダ保持部に装着された容器ホルダに対して混練容器を脱着操作する、或いは、回転体の容器ホルダ保持部に対して混練容器を装着してある容器ホルダを脱着操作するといった具合に、容器ホルダ及び混練容器の取り扱い操作の多様化を図ることができる。   According to the above configuration, the kneading container is attached to and detached from the container holder attached to the container holder holding part of the rotating body, or the container holder in which the kneading container is attached to the container holder holding part of the rotating body. The handling operation of the container holder and the kneading container can be diversified in such a manner that the detaching operation is performed.

本発明による第３の特徴構成は、前記混練容器は、外径、高さの少なくとも一方が異なる複数種類の蓋付き混練容器から構成され、前記容器ホルダには、前記混練容器をそれの蓋が前記容器ホルダの内面に接触しない位置に配置保持する補助ホルダが脱着自在に設けられている点にある。   According to a third characteristic configuration of the present invention, the kneading container is composed of a plurality of types of kneading containers with lids having different outer diameters and heights, and the container holder includes the kneading container and the lid thereof. An auxiliary holder that is disposed and held at a position that does not contact the inner surface of the container holder is detachably provided.

上記構成によれば、容器ホルダに装着される混練容器の蓋が容器ホルダの内面に接触する場合には、容器ホルダに補助ホルダを装着することにより、混練容器をそれの蓋が容器ホルダの内面に接触しない位置に配置保持することができるので、混練容器の蓋の外れによる被混練材料の飛び出しを回避することができる。   According to the above configuration, when the lid of the kneading container attached to the container holder contacts the inner surface of the container holder, the auxiliary holder is attached to the container holder so that the lid of the kneading container becomes the inner surface of the container holder. Therefore, the material to be kneaded can be prevented from popping out due to the removal of the lid of the kneading container.

本発明による第４の特徴構成は、前記容器ホルダの周壁部の内面には、当該内面よりも径方向内方に突出する弾性体が設けられている点にある。   A fourth characteristic configuration according to the present invention is that an inner surface of the peripheral wall portion of the container holder is provided with an elastic body projecting radially inward from the inner surface.

上記構成によれば、公転開始時の遠心力で混練容器が容器ホルダ内の径方向に移動したとき、容器ホルダの内側面よりも径方向内方に突出する弾性体に当接するため、容器ホルダの内面と混練容器の外面との当接音を低減することができる。しかも、この弾性体を介して混練容器の外面と容器ホルダの内面との間での摩擦力を高めることができるので、混練容器と容器ホルダとが一層一体的に自転する。   According to the above configuration, when the kneading container is moved in the radial direction in the container holder by the centrifugal force at the start of revolution, the container holder comes into contact with the elastic body protruding radially inward from the inner side surface of the container holder. The contact sound between the inner surface of the kneading container and the outer surface of the kneading container can be reduced. In addition, since the frictional force between the outer surface of the kneading container and the inner surface of the container holder can be increased via this elastic body, the kneading container and the container holder rotate more integrally.

本発明による第５の特徴構成は、前記補助ホルダの内面と前記混練容器の外面との間に前記融通が形成されている点にある。   A fifth characteristic configuration according to the present invention is that the interchange is formed between an inner surface of the auxiliary holder and an outer surface of the kneading container.

上記構成によれば、混練容器をそれの蓋が容器ホルダの内面に接触しない位置に配置保持するための補助ホルダを、容器ホルダに自転軸芯周りで一体回転する状態で装着しても、この補助ホルダの内面と混練容器の外面との間には融通が形成されているので、構造の簡素化とコストの低廉化及び混練容器の脱着操作の容易化を図りながら、被混練材料を公転と自転とによって適切に混練することができる。   According to the above configuration, even if the auxiliary holder for arranging and holding the kneading container at a position where the lid of the kneading container does not contact the inner surface of the container holder is attached to the container holder so as to rotate integrally around the rotation axis, Since a space is formed between the inner surface of the auxiliary holder and the outer surface of the kneading container, the material to be kneaded is revolved while simplifying the structure, reducing the cost, and facilitating the detaching operation of the kneading container. It can knead | mix appropriately by autorotation.

本発明の混練装置の全体の一部切欠き正面図1 is a partially cutaway front view of the entire kneading apparatus of the present invention. 容器ホルダに１００ｇ用の二種の混練容器を装着したときの断面図Sectional view when two types of kneading containers for 100g are attached to the container holder 容器ホルダに補助ホルダを介して５０ｇ用の二種の混練容器を装着したときの断面図Sectional view when two types of kneading containers for 50 g are attached to the container holder via the auxiliary holder 容器ホルダに補助ホルダを介して３０ｇ〜１０ｇ用の二種の混練容器を装着したときの断面図Sectional drawing when two types of kneading containers for 30 g to 10 g are attached to the container holder via the auxiliary holder

本発明の実施形態を図面に基づいて説明する。
図１は、被混練材料の一例である軟膏、貼付剤、眼軟膏剤等の医薬品製剤を公転と自転とによって混練する混練装置を示す。この混練装置は、四隅に配設したゴム製の接地体１ａ付きのアジャスト１を介して高さ調節可能に構成された金属製の基礎底板２に、操作パネル（図示せず）を備えた上方開口のハウジング３が取付けられている。このハウジング３の上側開口部には、後面側の水平軸芯周りで上下方向に揺動開閉自在な上部カバー４が枢着され、基礎底板２とハウジング３及び上部カバー４とで囲まれた内部に装置配設空間５が形成されている。 Embodiments of the present invention will be described with reference to the drawings.
FIG. 1 shows a kneading apparatus for kneading a pharmaceutical preparation such as an ointment, a patch, and an eye ointment, which is an example of a material to be kneaded, by revolution and rotation. This kneading apparatus is provided with an operation panel (not shown) provided on a metal base bottom plate 2 that can be adjusted in height through an adjust 1 with a rubber grounding body 1a disposed at four corners. An open housing 3 is attached. An upper cover 4 is pivotally attached to the upper opening of the housing 3 so as to be swingable in the vertical direction around the horizontal axis on the rear side, and is surrounded by the base bottom plate 2, the housing 3 and the upper cover 4. An apparatus installation space 5 is formed in the upper part.

装置配設空間５内の基礎底板２には、防振ゴム６を介して金属製の防振台７が取付けられている。この防振台７の上部には、公転軸８を上下方向（鉛直方向）となる公転軸芯Ｙ１周りで回転自在に支承する公転軸受部９がボルト等の締結手段で固定連結されている。公転軸受部９の下端部には、公転軸８の下端部に形成された連結孔８ａに一体回転状態で嵌合連結される駆動軸１０を備えた公転駆動手段の一例である公転駆動用モータ１１がボルト等の締結手段で固定連結されている。   A vibration isolation table 7 made of metal is attached to the foundation bottom plate 2 in the apparatus installation space 5 via a vibration isolation rubber 6. A revolving bearing portion 9 that rotatably supports the revolving shaft 8 around a revolving axis Y1 that is in the vertical direction (vertical direction) is fixedly connected to the upper part of the vibration isolator 7 by fastening means such as bolts. A revolution drive motor, which is an example of a revolution drive means, is provided with a drive shaft 10 fitted and connected to a connection hole 8a formed in the lower end of the revolution shaft 8 at the lower end portion thereof. 11 is fixedly connected by fastening means such as bolts.

公転軸８の上端軸部に一体回転状態で固定連結された枠状の回転体１２の回転半径方向の一端部には、上方開口の容器ホルダ２１を脱着自在に収納保持する上方開口の容器ホルダ保持部２０が、公転軸８の公転軸芯Ｙ１に対して４５度の傾斜角度で交差する自転軸芯Ｙ２周りで回転自在に設けられている。詳しくは、回転体１２の回転半径方向の一端部には、公転軸８の公転軸芯Ｙ１に対して４５度の傾斜角度で軸受け軸芯が交差する自転軸受け部１３が設けられ、この自転軸受け部１３に、容器ホルダ保持部２０の底壁部２０ｂの中心位置から下方に一体的に突出形成された自転筒軸部２０ｃが自転軸芯Ｙ２周りで回転自在に支承されている。   An upper opening container holder that detachably accommodates and holds an upper opening container holder 21 at one end in the rotational radius direction of a frame-like rotating body 12 that is fixedly connected to the upper end shaft part of the revolution shaft 8 in an integrally rotated state. The holding portion 20 is provided so as to be rotatable around a rotation axis Y2 that intersects the revolution axis Y1 of the revolution axis 8 at an inclination angle of 45 degrees. Specifically, a rotating bearing portion 13 is provided at one end in the rotational radius direction of the rotating body 12 so that the bearing shaft intersects the revolving shaft core Y1 of the revolving shaft 8 at an inclination angle of 45 degrees. A rotating cylinder shaft portion 20c integrally formed so as to protrude downward from the center position of the bottom wall portion 20b of the container holder holding portion 20 is supported on the portion 13 so as to be rotatable around the rotation axis Y2.

容器ホルダ保持部２０を公転軸８の駆動回転に連動して自転軸芯Ｙ２周りで駆動回転させる自転駆動手段３０が設けられている。
これにより、回転体１２の容器ホルダ保持部２０に容器ホルダ２１を介して蓋２２付きの混練容器２３を装着することにより、公転軸芯Ｙ１回りでの公転運動と自転軸芯Ｙ２周りでの自転運動とにより、混練容器２３内の医薬品製剤を効率良く均一に混練処理することができる。 A rotation driving means 30 is provided for driving and rotating the container holder holding portion 20 around the rotation axis Y2 in conjunction with the rotation of the revolution shaft 8.
Thus, by attaching the kneading container 23 with the lid 22 to the container holder holding part 20 of the rotating body 12 via the container holder 21, the revolving motion around the revolution axis Y1 and the rotation around the revolution axis Y2. By the exercise, the pharmaceutical preparation in the kneading container 23 can be kneaded efficiently and uniformly.

自転駆動手段３０には、公転軸受部９の外周面にプーリー溝３１ａを形成して、公転軸受部９に一体化された駆動側のプーリー部３１と、容器ホルダ保持部２０の底壁部２０ｂの自転筒軸部２０ｃに一体回転状態で外嵌固定された受動側のプーリー３２と、駆動側のプーリー部３１から受動側のプーリー３２に自転用の回転力を伝達する無端状の伝動ベルト３３とが備えられている。さらに、伝動ベルト３３の水平面回動部と傾斜面回動部との屈曲部位を案内するガイドプーリー３４が回転体１２に取付けられている。   In the rotation driving means 30, a pulley groove 31 a is formed on the outer peripheral surface of the revolution bearing portion 9, the driving pulley portion 31 integrated with the revolution bearing portion 9, and the bottom wall portion 20 b of the container holder holding portion 20. A passive pulley 32 that is externally fitted and fixed to the rotating cylindrical shaft portion 20c of the rotating cylinder shaft portion 20c, and an endless transmission belt 33 that transmits rotational torque from the driving pulley portion 31 to the passive pulley 32. And are provided. Further, a guide pulley 34 that guides the bent portion of the horizontal rotation portion and the inclined surface rotation portion of the transmission belt 33 is attached to the rotating body 12.

また、回転体１２の回転半径方向の他端部には、公転軸８の公転軸芯Ｙ１からの錘４２の距離を変更して、容器ホルダ２１に脱着自在に装着される蓋２２付き混練容器２３の質量に応じた重量バランスに調節する重量バランス調節手段４０が設けられている。
この重量バランス調節手段４０は、回転体１２の回転半径方向の他端部に固定連結される金属製の取付けプレート４１に、回転体１２の回転半径方向である公転半径方向に移動自在な金属製の錘４２と、この錘４２に当接した状態での縦軸芯周りでの回転操作によって当該錘４２を公転半径方向に移動させる金属製の回転カム４３と、公転軸芯Ｙ１側から公転半径方向に沿って錘４２を回転カム４３のカム面に当接付勢する圧縮コイルばね等の弾性付勢体４４とを装備して構成されている。 In addition, the kneading container with the lid 22 is detachably attached to the container holder 21 by changing the distance of the weight 42 from the revolution axis Y1 of the revolution shaft 8 to the other end portion in the rotational radius direction of the rotating body 12. A weight balance adjusting means 40 for adjusting the weight balance according to the mass of 23 is provided.
The weight balance adjusting means 40 is made of a metal that is movable in a revolving radial direction that is the rotational radius direction of the rotating body 12, on a metal mounting plate 41 that is fixedly connected to the other end of the rotating body 12 in the rotational radius direction. , A metal rotating cam 43 that moves the weight 42 in the revolving radius direction by a rotation operation around the vertical axis while being in contact with the weight 42, and a revolving radius from the revolving axis Y1 side. An elastic biasing body 44 such as a compression coil spring that biases the weight 42 against the cam surface of the rotating cam 43 along the direction is provided.

容器ホルダ２１の周壁部２１ａの外径は、容器ホルダ保持部２０の周壁部２０ａの内径よりも僅かに小径に構成され、容器ホルダ保持部２０に対して容器ホルダ２１がガタツキの無い状態で装着保持される。また、図１に示すように、容器ホルダ保持部２０の底壁部２０ｂと容器ホルダ２１の底壁部２１ｂとの間には、滑り止め部材の一例であるシリコン製の滑り止めマット２５が脱着自在に介装されている。
公転駆動用モータ１１の駆動による公転回転時の遠心力により、容器ホルダ２１の周壁部２１ｂが容器ホルダ保持部２０の周壁部２０ａに押し付けられ、且つ、容器ホルダ２１の底壁部２１ｂが滑り止めマット２５を介して容器ホルダ保持部２０の底壁部２０ｂに押し付けられる。そのため、公転駆動用モータ１１の駆動回転力が自転駆動手段３０を介して容器ホルダ保持部２０に伝達されると、容器ホルダ保持部２０と容器ホルダ２１とが自転軸芯Ｙ２周りで一体回転する。 The outer diameter of the peripheral wall portion 21a of the container holder 21 is configured to be slightly smaller than the inner diameter of the peripheral wall portion 20a of the container holder holding portion 20, and the container holder 21 is attached to the container holder holding portion 20 without rattling. Retained. Further, as shown in FIG. 1, a non-slip mat 25 made of silicon, which is an example of an anti-slip member, is attached and detached between the bottom wall part 20b of the container holder holding part 20 and the bottom wall part 21b of the container holder 21. It is freely inserted.
The peripheral wall portion 21b of the container holder 21 is pressed against the peripheral wall portion 20a of the container holder holding portion 20 and the bottom wall portion 21b of the container holder 21 is prevented from slipping by the centrifugal force at the time of revolving rotation by driving the revolution drive motor 11. It is pressed against the bottom wall portion 20 b of the container holder holding portion 20 through the mat 25. Therefore, when the driving rotational force of the revolution drive motor 11 is transmitted to the container holder holding part 20 via the rotation driving means 30, the container holder holding part 20 and the container holder 21 rotate integrally around the rotation axis Y2. .

そして、本実施形態では、図２に示すように、容器ホルダ２１の周壁部２１ａの内径を混練容器２３の周壁部２３ａの外径よりも大径に構成して、容器ホルダ２１の周壁部２１ａの内面と混練容器２３の周壁部２３ａの外面との間に、容器ホルダ２１に対する混練容器２３の径方向への移動を許容する融通Ｓが形成されている。
また、図３、図４に示すように、容器ホルダ２１に、混練容器２３をそれの蓋２２が容器ホルダ２１の内面に接触しない位置に配置保持する補助ホルダ２４が脱着自在に装着されている場合においても、補助ホルダ２４の周壁部２４ａの内径を混練容器２３の周壁部２３ａの外径よりも大径に構成して、補助ホルダ２４の周壁部２４ａの内面と混練容器２３の周壁部２３ａの外面との間に、容器ホルダ２１及び補助ホルダ２４に対する混練容器２３の径方向への移動を許容する融通Ｓが形成されている。 In this embodiment, as shown in FIG. 2, the inner diameter of the peripheral wall portion 21 a of the container holder 21 is configured to be larger than the outer diameter of the peripheral wall portion 23 a of the kneading container 23, so that the peripheral wall portion 21 a of the container holder 21. Between the inner surface of the kneading container 23 and the outer surface of the peripheral wall portion 23 a of the kneading container 23, an accommodation S that allows the kneading container 23 to move in the radial direction with respect to the container holder 21 is formed.
As shown in FIGS. 3 and 4, the container holder 21 is detachably mounted with an auxiliary holder 24 that holds and holds the kneading container 23 in a position where the lid 22 does not contact the inner surface of the container holder 21. Even in such a case, the inner diameter of the peripheral wall portion 24a of the auxiliary holder 24 is configured to be larger than the outer diameter of the peripheral wall portion 23a of the kneading vessel 23, and the inner surface of the peripheral wall portion 24a of the auxiliary holder 24 and the peripheral wall portion 23a of the kneading vessel 23 are. A space S is formed between the outer surface and the container holder 21 and the auxiliary holder 24 to allow the kneading container 23 to move in the radial direction.

そして、図２に示すように、上述の容器ホルダ２１の周壁部２１ａの内面と混練容器２３の周壁部２３ａの外面との間に設けられた融通Ｓにより、容器ホルダ２１に対する混練容器２３の脱着操作を容易に行うことができる。また、図３、図４に示すように、補助ホルダ２４の周壁部２４ａの内面と混練容器２３の周壁部２３ａの外面との間に設けられた融通Ｓにより、補助ホルダ２４に対する混練容器２３の脱着操作を容易に行うことができる。   Then, as shown in FIG. 2, the kneading container 23 is attached to and detached from the container holder 21 by the accommodation S provided between the inner surface of the peripheral wall portion 21a of the container holder 21 and the outer surface of the peripheral wall portion 23a of the kneading container 23. Operation can be performed easily. Further, as shown in FIGS. 3 and 4, the kneading container 23 is connected to the auxiliary holder 24 by the interchange S provided between the inner surface of the peripheral wall 24 a of the auxiliary holder 24 and the outer surface of the peripheral wall 23 a of the kneading container 23. Desorption operation can be easily performed.

上述の構成により、混練装置の自転部Ａは、容器ホルダ保持部２０、容器ホルダ２１、混練容器２３を備えた混錬量の多い側の第１使用形態と、容器ホルダ保持部２０、容器ホルダ２１、補助ホルダ２４、混練容器２３を備えた混錬量の少ない側の第２使用形態とが存在する。各使用形態の自転部構成要素のうち、混練装置に固定的に設けられる容器ホルダ保持部２０等の固定自転部構成要素を除く脱着自転部構成要素の総重量（総質量）を重量バランス調節が不要な設定範囲内に構成する。つまり、第１使用形態においては、容器ホルダ２１、混練容器２３、これに収納される医薬品製剤の総重量を、第２使用形態においては、容器ホルダ２１、補助ホルダ２４、混練容器２３、これに収納される医薬品製剤の総重量を、いずれの使用形態を採用しても重量バランス調節手段４０を再調整する必要の無い設定範囲（例えば、１９０ｇ〜２５０g）内に収まるように構成する。
この脱着自転部構成要素の総重量の調整は、補助ホルダ２４の形状及び材質の設定により設定範囲内に収めている。 With the above-described configuration, the rotation part A of the kneading apparatus includes the container holder holding part 20, the container holder 21, and the first usage pattern on the side with a large kneading amount provided with the kneading container 23, the container holder holding part 20, and the container holder. 21, the auxiliary holder 24, and the kneading container 23, and the second usage pattern on the side with a smaller kneading amount exists. The weight balance adjustment is possible for the total weight (total mass) of the detachable rotation portion components excluding the fixed rotation portion components such as the container holder holding portion 20 fixedly provided in the kneading apparatus among the rotation portion components of each use form. Configure within an unnecessary setting range. That is, in the first usage pattern, the total weight of the container holder 21, the kneading container 23, and the pharmaceutical preparation stored in the container holder 21, the auxiliary holder 24, the kneading container 23, The total weight of the stored pharmaceutical preparation is configured to be within a set range (for example, 190 g to 250 g) that does not require readjustment of the weight balance adjusting means 40 regardless of the usage form.
Adjustment of the total weight of the detachable rotation part component is within a set range by setting the shape and material of the auxiliary holder 24.

補助ホルダ２４の周壁部２４ａの外径は、容器ホルダ２１の周壁部２１ａの内径よりも僅かに小径に構成され、容器ホルダ２１に対して補助ホルダ２４がガタツキの無い状態で装着保持される。
また、容器ホルダ２１の周壁部２１ａの上下中間部位には、容器ホルダ２１の中心線側に向かって開口する周溝２６が形成され、この周溝２６には、容器ホルダ２１の周壁部２１ａの内面よりも径方向内方に突出する緩衝用及び挟持用のゴムリング等の弾性体２７が設けられている。この弾性体２７の内径は、補助ホルダ２４の周壁部２４ａの外径よりも小に構成されている。 The outer diameter of the peripheral wall portion 24 a of the auxiliary holder 24 is configured to be slightly smaller than the inner diameter of the peripheral wall portion 21 a of the container holder 21, and the auxiliary holder 24 is mounted and held on the container holder 21 without any backlash.
In addition, a circumferential groove 26 that opens toward the center line side of the container holder 21 is formed in an upper and lower intermediate portion of the circumferential wall portion 21 a of the container holder 21, and the circumferential groove 26 has a circumferential groove portion 21 a of the container holder 21. An elastic body 27 such as a shock absorbing and clamping rubber ring that protrudes radially inward from the inner surface is provided. The inner diameter of the elastic body 27 is configured to be smaller than the outer diameter of the peripheral wall portion 24 a of the auxiliary holder 24.

そのため、図２に示すように、容器ホルダ２１内に混練容器２３が直接装着されている場合では、公転開始時の遠心力で混練容器２３が容器ホルダ２１内の径方向に移動したとき、容器ホルダ２１の内側面よりも径方向内方に突出する弾性体２７に当接するため、容器ホルダ２１の周壁部２１ａの内面と混練容器２３の周壁部２３ａの外面との当接音を低減することができる。しかも、この弾性体２７を介して混練容器２３の周壁部２３ａの外面と容器ホルダ２１の周壁部２１ａの内面との間での摩擦力を高めることができるので、混練容器と容器ホルダとが一層一体的に自転する。   Therefore, as shown in FIG. 2, when the kneading container 23 is directly mounted in the container holder 21, when the kneading container 23 is moved in the radial direction in the container holder 21 by the centrifugal force at the start of revolution, the container The contact sound between the inner surface of the peripheral wall portion 21a of the container holder 21 and the outer surface of the peripheral wall portion 23a of the kneading vessel 23 is reduced because the elastic member 27 protrudes radially inward from the inner surface of the holder 21. Can do. In addition, since the frictional force between the outer surface of the peripheral wall portion 23a of the kneading container 23 and the inner surface of the peripheral wall portion 21a of the container holder 21 can be increased via the elastic body 27, the kneading container and the container holder are further increased. Rotate together.

また、図３、図４に示すように、容器ホルダ２１内に補助ホルダ２４が装着されている場合には、補助ホルダ２４の周壁部２４ａの外面で弾性体２７を径方向外方側に押圧して圧縮する。そのため、補助ホルダ２４は、容器ホルダ２１に対して弾性体２７の弾性復元力で挟持された状態となり、容器ホルダ２１と補助ホルダ２４とが自転軸芯Ｙ２周りで一体回転する。   3 and 4, when the auxiliary holder 24 is mounted in the container holder 21, the elastic body 27 is pressed radially outward on the outer surface of the peripheral wall portion 24a of the auxiliary holder 24. And compress. Therefore, the auxiliary holder 24 is sandwiched by the elastic restoring force of the elastic body 27 with respect to the container holder 21, and the container holder 21 and the auxiliary holder 24 rotate integrally around the rotation axis Y2.

そして、公転駆動用モータ１１を駆動制御する制御部において、公転駆動用モータ１１による容器ホルダ２１の公転回転速度を、公転回転時の遠心力で混練容器２３の外面が容器ホルダ２１の内面又は補助ホルダ２４の内面に押し付けられ、且つ、その押し付けられた混練容器２３の外面と容器ホルダ２１の内面又は補助ホルダ２４の内面との間での摩擦力で混練容器２３が容器ホルダ２１又は補助ホルダ２４と一体的に自転する公転回転速度に設定してある。
この公転回転速度は、遠心力の変動要因となる混練容器２３の重量、遠心力による摩擦力の変動要因になる混練容器２３や容器ホルダ２１や補助ホルダ２４の素材や形状等の動作条件に応じ、例えば、同一の動作条件において異なる公転回転速度で試験動作させる等により、適切に動作する公転回転速度を簡単に求めて設定することができる。
本実施形態においては、公転回転数は１５００ｒｐｍ〜２０００ｒｐｍ、自転回転数は６００ｒｐｍ〜９００ｒｐｍ、公転半径（公転軸芯Ｙ１と混練容器２３の重心位置との水平方向の距離）は７０ｍｍ〜１００ｍｍ、相対遠心力は約１７６ｇ〜４４７ｇの各範囲内に設定してある。
尚、容器ホルダ保持部２０に容器ホルダ２１を装着して公転駆動用モータ１１を駆動回転させたとき、容器ホルダ保持部２０と容器ホルダ２１とは自転軸芯Ｙ２周りで一体回転状態に構成されている。また、容器ホルダ２１に補助ホルダ２４を装着して公転駆動用モータ１１を駆動回転させたとき、容器ホルダ２１と補助ホルダ２４も自転軸芯Ｙ２周りで一体回転状態に構成されている。 And in the control part which drives and controls the revolution drive motor 11, the outer surface of the kneading container 23 is made the inner surface of the container holder 21 or the auxiliary by the centrifugal force at the time of the revolution. The kneading container 23 is pressed against the inner surface of the holder 24, and the kneading container 23 is brought into contact with the inner surface of the container holder 21 or the auxiliary holder 24 by the frictional force between the outer surface of the pressed kneading container 23 and the inner surface of the auxiliary holder 24. Is set to the revolution speed that rotates in unison.
This revolution speed depends on the operating conditions such as the weight and the shape of the kneading container 23, the container holder 21, and the auxiliary holder 24 that cause the fluctuation of the frictional force due to the centrifugal force. For example, by performing a test operation at different revolution speeds under the same operating conditions, it is possible to easily obtain and set an appropriate revolution speed.
In this embodiment, the revolution speed is 1500 rpm to 2000 rpm, the rotation speed is 600 rpm to 900 rpm, the revolution radius (the horizontal distance between the revolution axis Y1 and the center of gravity of the kneading vessel 23) is 70 mm to 100 mm, and the relative centrifugation The force is set in each range of about 176 g to 447 g.
When the container holder 21 is mounted on the container holder holding part 20 and the revolution driving motor 11 is driven and rotated, the container holder holding part 20 and the container holder 21 are configured to rotate integrally around the rotation axis Y2. ing. Further, when the auxiliary holder 24 is mounted on the container holder 21 and the revolution driving motor 11 is driven and rotated, the container holder 21 and the auxiliary holder 24 are also integrally rotated around the rotation axis Y2.

そして、上述の公転回転速度の設定により、容器ホルダ２１の内面と混練容器２３の外面との間、又は、補助ホルダ２４の内面と混練容器２３の外面との間に上述の融通Ｓが設けられていても、公転駆動用モータ１１によって容器ホルダ２１が公転軸芯Ｙ１周りで駆動回転されると、公転回転時の遠心力により、混練容器２３が容器ホルダ２１又は補助ホルダ２４の径方向に移動し、混練容器２３の周壁部２３ａの外面が容器ホルダ２１の周壁部２１ａの内面又は補助ホルダ２４の周壁部２４ａの内面に押し付けられる。このとき、自転軸芯Ｙ２は公転軸芯Ｙ１に対して４５度の角度で傾斜しているため、公転回転時の遠心力により、混練容器２３の底壁部２３ｂの外面が容器ホルダ２１の底壁部２１ｂの内面又は補助ホルダ２４の底壁部の内面にも押し付けられる。
この押し付け状態において、自転駆動手段３０によって容器ホルダ２１又は容器ホルダ２１と補助ホルダ２４が自転軸芯Ｙ２周りで駆動回転されるので、混練容器２３の外面と容器ホルダ２１の内面又は補助ホルダ２４との間での摩擦力により、混練容器２３が容器ホルダ２１又は補助ホルダ２４と一体的に自転する。 Then, the above-mentioned accommodation S is provided between the inner surface of the container holder 21 and the outer surface of the kneading container 23 or between the inner surface of the auxiliary holder 24 and the outer surface of the kneading container 23 depending on the setting of the revolution speed described above. However, when the container holder 21 is driven and rotated around the revolution axis Y1 by the revolution drive motor 11, the kneading container 23 moves in the radial direction of the container holder 21 or the auxiliary holder 24 by the centrifugal force at the revolution rotation. The outer surface of the peripheral wall portion 23 a of the kneading container 23 is pressed against the inner surface of the peripheral wall portion 21 a of the container holder 21 or the inner surface of the peripheral wall portion 24 a of the auxiliary holder 24. At this time, since the rotation axis Y2 is inclined at an angle of 45 degrees with respect to the revolution axis Y1, the outer surface of the bottom wall portion 23b of the kneading container 23 is bottomed by the bottom of the container holder 21 by centrifugal force during revolution rotation. It is also pressed against the inner surface of the wall portion 21 b or the inner surface of the bottom wall portion of the auxiliary holder 24.
In this pressed state, the container holder 21 or the container holder 21 and the auxiliary holder 24 are driven and rotated around the rotation axis Y2 by the rotation driving means 30, so that the outer surface of the kneading container 23 and the inner surface of the container holder 21 or the auxiliary holder 24 The kneading vessel 23 rotates integrally with the vessel holder 21 or the auxiliary holder 24 by the friction force between them.

混練容器２３の中心Ｙ３が容器ホルダ２１又は補助ホルダ２４の自転軸芯Ｙ２から位置ずれしても、自転によって混練容器２３に加わる遠心力Ｆ１は、医薬品製剤を収納した容器ホルダ２１の重量（質量）をｍ、自転角速度をω、混練容器２３の半径をｒとするとき、
遠心力Ｆ１＝ｍ×ｒ×ω２
上記式で決まるため、混練容器２３の中心Ｙ３が容器ホルダ２１又は補助ホルダ２４の自転軸芯Ｙ２から位置ずれすることによる影響はない。
それ故に、混練容器２３をそれの中心Ｙ３が自転軸芯Ｙ２上に位置する状態で当該混練容器２３の下端部の周方向複数個所を径方向から挾持する容器保持固定手段や混練容器２３を容器ホルダ２１の底壁に押圧する押圧手段等を設ける必要がなく、また、混練容器２３の種類に応じた内径の複数種類の容器ホルダ又はアダプタを製作する必要もない。
したがって、構造の簡素化とコストの低廉化及び混練容器２３の脱着操作の容易化を図りながら、医薬品製剤を公転と自転とによって適切に混練することができる。 Even if the center Y3 of the kneading container 23 is displaced from the rotation axis Y2 of the container holder 21 or the auxiliary holder 24, the centrifugal force F1 applied to the kneading container 23 by rotation is the weight (mass) of the container holder 21 containing the pharmaceutical preparation. ) Is m, the rotational angular velocity is ω, and the radius of the kneading vessel 23 is r,
Centrifugal force F1 = m × r × ω2
Since it is determined by the above formula, there is no influence due to the displacement of the center Y3 of the kneading vessel 23 from the rotation axis Y2 of the vessel holder 21 or the auxiliary holder 24.
Therefore, the container holding and fixing means for holding the kneading container 23 from the radial direction at a plurality of circumferential positions at the lower end of the kneading container 23 with the center Y3 of the kneading container 23 positioned on the rotation axis Y2 is used as the container. There is no need to provide a pressing means for pressing the bottom wall of the holder 21, and there is no need to manufacture a plurality of types of container holders or adapters having an inner diameter corresponding to the type of the kneading container 23.
Therefore, the pharmaceutical preparation can be appropriately kneaded by revolution and rotation while simplifying the structure, reducing the cost, and facilitating the desorption operation of the kneading container 23.

容器ホルダ２１は、ポリアセタール樹脂（ＰＯＭ）製で、周壁部２１ａには、混練容器２３及び補助ホルダ２４を容易に脱着操作するための略Ｕ字状の切欠き部２１ｄが形成され、周壁部２１ａの外周面の上端部には、指の掛かりを良くするための指掛け用溝２１ｅが形成されている。また、底壁部２１ｂには、万が一、容器ホルダ２１の内径と同径に構成された混練容器２３が装着された場合において、この同径の混練容器２３を底部側から押し出し操作するための開口部２１ｆが形成されている。   The container holder 21 is made of polyacetal resin (POM), and a substantially U-shaped notch 21d for easily attaching and detaching the kneading container 23 and the auxiliary holder 24 is formed on the peripheral wall 21a, and the peripheral wall 21a. A finger hooking groove 21e is formed at the upper end of the outer peripheral surface of the outer peripheral surface to improve the hooking of the finger. In addition, when the kneading container 23 having the same diameter as the inner diameter of the container holder 21 is attached to the bottom wall portion 21b, an opening for pushing out the kneading container 23 having the same diameter from the bottom side. A portion 21f is formed.

混練容器２３としては、外径、高さ、医薬品製剤の収納容量の異なる多種類の混練容器２３が存在し、その何れの混練容器２３も使用することができるが、本実施形態においては、図２〜図４に示すように、第１混練容器２３Ａ〜第６混練容器２３Ｆの６種類を例示した。
図２の（ａ）に示す第１混練容器２３Ａは、医薬品製剤の収納容量が１００ｇの容器であり、第１混練容器２３Ａの底面から蓋２２の上面までの高さが、容器ホルダ２１の周壁部２１ａの内面高さと同一に構成されている。そのため、容器ホルダ２１の周壁部２１ａの内面の上側部には、第１混練容器２３Ａの蓋２２の径方向外方への突出代よりも大きな寸法で径方向外方側に窪む蓋接触回避手段としての環状溝２１ｃが形成され、第１混練容器２３Ａの蓋２２が容器ホルダ２１の周壁部２１ａの内面に接触することを防止している。この場合、補助ホルダ２４を使用しない第１使用形態の一例となる。 As the kneading container 23, there are various types of kneading containers 23 having different outer diameters, heights, and storage capacities of pharmaceutical preparations, and any of these kneading containers 23 can be used. As shown in FIGS. 2 to 4, six types of first kneading containers 23 </ b> A to sixth kneading containers 23 </ b> F are illustrated.
The first kneading container 23A shown in FIG. 2A is a container having a storage capacity of 100 g of pharmaceutical preparation, and the height from the bottom surface of the first kneading container 23A to the upper surface of the lid 22 is the peripheral wall of the container holder 21. The inner surface height of the portion 21a is the same. Therefore, on the upper side of the inner surface of the peripheral wall portion 21a of the container holder 21, the lid contact avoidance that is recessed in the radially outward side with a size larger than the radially outward projection allowance of the lid 22 of the first kneading container 23A. An annular groove 21c as a means is formed to prevent the lid 22 of the first kneading vessel 23A from contacting the inner surface of the peripheral wall portion 21a of the vessel holder 21. In this case, this is an example of a first usage pattern in which the auxiliary holder 24 is not used.

また、医薬品製剤を含めた第１混練容器２３Ａの重量が大きいため、容器ホルダ２１、第１混練容器２３Ａ、これに収納される医薬品製剤を含む総重量は、重量バランス調節手段４０を再調整する必要の無い設定範囲（例えば、１９０ｇ〜２５０g）内に設定されている。   Further, since the weight of the first kneading container 23A including the pharmaceutical preparation is large, the total weight including the container holder 21, the first kneading container 23A, and the pharmaceutical preparation stored in the container 21 re-adjusts the weight balance adjusting means 40. It is set within an unnecessary setting range (for example, 190 g to 250 g).

図２の（ｂ）に示す第２混練容器２３Ｂは、上述と同様に、医薬品製剤の収納容量が１００ｇの容器であるが、第２混練容器２３Ｂの底面から蓋２２の下端までの高さが、容器ホルダ２１の周壁部２１ａの内面高さよりも大で、第２混練容器２３Ｂの蓋２２が容器ホルダ２１の周壁部２１ａよりも上方に飛び出す。そのため、第２混練容器２３Ｂの蓋２２が容器ホルダ２１の周壁部２１ａの内面に接触することはない。この場合も、補助ホルダ２４を使用しない第１使用形態の一例となる。   The second kneading container 23B shown in (b) of FIG. 2 is a container having a storage capacity of 100 g of the pharmaceutical preparation as described above, but the height from the bottom surface of the second kneading container 23B to the lower end of the lid 22 is the same. The lid 22 of the second kneading container 23 </ b> B jumps upward from the peripheral wall 21 a of the container holder 21, which is larger than the inner surface height of the peripheral wall 21 a of the container holder 21. Therefore, the lid 22 of the second kneading container 23 </ b> B does not contact the inner surface of the peripheral wall portion 21 a of the container holder 21. This is also an example of a first usage pattern in which the auxiliary holder 24 is not used.

また、医薬品製剤を含めた第２混練容器２３Ｂは、第１混練容器２３Ａと同様に重量が大きいため、容器ホルダ２１、第２混練容器２３Ｂ、これに収納される医薬品製剤を含む総重量は、重量バランス調節手段４０を再調整する必要の無い設定範囲（例えば、１９０ｇ〜２５０g）内に設定されている。   Further, since the second kneading container 23B including the pharmaceutical preparation has a large weight in the same manner as the first kneading container 23A, the total weight including the container holder 21, the second kneading container 23B, and the pharmaceutical preparation stored therein is The weight balance adjusting means 40 is set within a setting range (for example, 190 g to 250 g) that does not require readjustment.

図３の（ｂ）に示す第３混練容器２３Ｃは、医薬品製剤の収納容量が５０ｇの容器であり、第３混練容器２３Ｃの底面から蓋２２の下端までの高さが、容器ホルダ２１の周壁部２１ａの内面のうち、それの上側部に形成されている環状溝２１ｃよりも下方の小内径側の内面部分の高さよりも小さい。そのため、補助ホルダ２４を用いて、第３混練容器２３Ｃの蓋２２が容器ホルダ２１の周壁部２１ａの内面に接触することを回避する。
補助ホルダ２４としても、図３に示す超高分子ポリエチレン製の第１補助ホルダ２４Ａと図４に示す超高分子ポリエチレン製の第２補助ホルダ２４Ｂとの２種類が存在する。そのうち、第３混練容器２３Ｃには、底壁部２４ｂの厚みが大きな第１補助ホルダ２４Ａを用いる。 The third kneading container 23C shown in FIG. 3 (b) is a container having a storage capacity of 50 g of pharmaceutical preparation, and the height from the bottom surface of the third kneading container 23C to the lower end of the lid 22 is the peripheral wall of the container holder 21. Of the inner surface of the portion 21a, the height is smaller than the height of the inner surface portion on the small inner diameter side below the annular groove 21c formed in the upper portion thereof. Therefore, the auxiliary holder 24 is used to avoid the lid 22 of the third kneading container 23 </ b> C from contacting the inner surface of the peripheral wall portion 21 a of the container holder 21.
As the auxiliary holder 24, there are two types, that is, a first auxiliary holder 24A made of ultra high molecular weight polyethylene shown in FIG. 3 and a second auxiliary holder 24B made of ultra high molecular weight polyethylene shown in FIG. Among them, the first auxiliary holder 24A having a large bottom wall portion 24b is used for the third kneading vessel 23C.

また、医薬品製剤を含めた第３混練容器２３Ｃの重量が小さいため、第１補助ホルダ２４Ａを用いる第２使用形態において、容器ホルダ２１、第１補助ホルダ２４Ａ、第３混練容器２３Ｃ、これに収納される医薬品製剤の総重量は、重量バランス調節手段４０を再調整する必要の無い設定範囲（例えば、１９０ｇ〜２５０g）内に設定されている。
また、第１補助ホルダ２４Ａの周壁部２４ａは、容器ホルダ２１に対する脱着操作を容易に行うためのものであり、この周壁部２４ａの外周面の上端部には、指の掛かりを良くするための指掛け用溝２４ｅが形成されている。 Further, since the weight of the third kneading container 23C including the pharmaceutical preparation is small, in the second usage mode using the first auxiliary holder 24A, the container holder 21, the first auxiliary holder 24A, the third kneading container 23C, and the container are stored in this. The total weight of the pharmaceutical preparation to be performed is set within a setting range (for example, 190 g to 250 g) that does not require the weight balance adjusting means 40 to be readjusted.
Further, the peripheral wall portion 24a of the first auxiliary holder 24A is for facilitating the detachment operation with respect to the container holder 21, and the upper end portion of the outer peripheral surface of the peripheral wall portion 24a is used for improving the finger hooking. A finger hanging groove 24e is formed.

図３の（ｃ）に示す第４混練容器２３Ｄは、医薬品製剤の収納容量が５０ｇの容器であり、第４混練容器２３Ｄの底面から蓋２２の下端までの高さが、容器ホルダ２１の周壁部２１ａの小内径側の内面部分の高さよりも大に構成されている。この場合、第４混練容器２３Ｄの蓋２２の径方向外方への突出代が、容器ホルダ２１の周壁部２１ａの内面の上側部に形成されている環状溝２１ｃの深さよりも小さいため、第４混練容器２３Ｄの蓋２２が容器ホルダ２１の周壁部２１ａの内面に接触することはない。
しかし、医薬品製剤を含めた第４混練容器２３Ｄの重量が小さいため、第１補助ホルダ２４Ａを重量調節部材として用いる。この第１補助ホルダ２４Ａを用いる第２使用形態において、容器ホルダ２１、第１補助ホルダ２４Ａ、第４混練容器２３Ｄ、これに収納される医薬品製剤の総重量は、重量バランス調節手段４０を再調整する必要の無い設定範囲（例えば、１９０ｇ〜２５０g）内に設定されている。 The fourth kneading container 23D shown in FIG. 3 (c) is a container having a storage capacity of 50 g of pharmaceutical preparation, and the height from the bottom surface of the fourth kneading container 23D to the lower end of the lid 22 is the peripheral wall of the container holder 21. It is configured to be larger than the height of the inner surface portion on the small inner diameter side of the portion 21a. In this case, the protrusion margin of the fourth kneading container 23D in the radially outward direction of the lid 22 is smaller than the depth of the annular groove 21c formed in the upper part of the inner surface of the peripheral wall portion 21a of the container holder 21. The lid 22 of the 4 kneading container 23 </ b> D does not contact the inner surface of the peripheral wall portion 21 a of the container holder 21.
However, since the weight of the fourth kneading container 23D including the pharmaceutical preparation is small, the first auxiliary holder 24A is used as the weight adjusting member. In the second usage pattern using the first auxiliary holder 24A, the total weight of the container holder 21, the first auxiliary holder 24A, the fourth kneading container 23D, and the pharmaceutical preparation stored therein is readjusted by the weight balance adjusting means 40. It is set within a setting range that does not need to be performed (for example, 190 g to 250 g).

図４の（ｂ）に示す第５混練容器２３Ｅは、医薬品製剤の収納容量が３０ｇの容器であり、第５混練容器２３Ｅの底面から蓋２２の下端までの高さが、容器ホルダ２１の周壁部２１ａの内面における小内径側の内面部分の高さよりも小さい。そのため、補助ホルダ２４として、図４(ａ)に示すように、周壁部２４ａの厚みが大きく、且つ、底壁部２４ｂが上下中間位置に配置された第２補助ホルダ２４Ｂを用いる。この第２補助ホルダ２４Ｂの底壁部２４ｂの一側面から周壁部２４ａの一端部までの第１装着凹部２４ｃの装着深さｈ１は、底壁部２４ｂの他側面から周壁部２４ａの他端部までの第２装着凹部２４ｄの装着深さｈ２よりも深く構成されている。   The fifth kneading container 23E shown in FIG. 4 (b) is a container having a storage capacity of 30 g of pharmaceutical preparation, and the height from the bottom surface of the fifth kneading container 23E to the lower end of the lid 22 is the peripheral wall of the container holder 21. It is smaller than the height of the inner surface portion on the small inner diameter side of the inner surface of the portion 21a. Therefore, as the auxiliary holder 24, as shown in FIG. 4A, a second auxiliary holder 24B in which the peripheral wall portion 24a is thick and the bottom wall portion 24b is disposed at the upper and lower intermediate positions is used. The mounting depth h1 of the first mounting recess 24c from one side surface of the bottom wall portion 24b of the second auxiliary holder 24B to one end portion of the peripheral wall portion 24a is the other end portion of the peripheral wall portion 24a from the other side surface of the bottom wall portion 24b. The second mounting recess 24d is deeper than the mounting depth h2.

そして、第２補助ホルダ２４Ｂの第１装着凹部２４ｃに第５混練容器２３Ｅを装着することにより、第５混練容器２３Ｅの蓋２２が、容器ホルダ２１の周壁部２１ａの内面に接触することはない。
また、医薬品製剤を含めた第５混練容器２３Ｅの重量は小さいため、第２補助ホルダ２４Ｂを重量調節部材として用いる。これにより、第２補助ホルダ２４Ｂを用いる第２使用形態において、容器ホルダ２１、第２補助ホルダ２４Ｂ、第５混練容器２３Ｅ、これに収納される医薬品製剤を含む総重量は、重量バランス調節手段４０を再調整する必要の無い設定範囲（例えば、１９０ｇ〜２５０g）内に設定されている。 Then, by mounting the fifth kneading container 23E in the first mounting recess 24c of the second auxiliary holder 24B, the lid 22 of the fifth kneading container 23E does not contact the inner surface of the peripheral wall portion 21a of the container holder 21. .
Further, since the weight of the fifth kneading container 23E including the pharmaceutical preparation is small, the second auxiliary holder 24B is used as the weight adjusting member. Thus, in the second usage pattern using the second auxiliary holder 24B, the total weight including the container holder 21, the second auxiliary holder 24B, the fifth kneading container 23E, and the pharmaceutical preparation stored in the container holder 21, the weight balance adjusting means 40 Is set within a setting range (for example, 190 g to 250 g) that does not require readjustment.

図４の（ｃ）に示す第６混練容器２３Ｆは、医薬品製剤の収納容量が１０ｇの容器であり、第６混練容器２３Ｆの底面から蓋２２の下端までの高さが、容器ホルダ２１の周壁部２１ａの内面における小内径側の内面部分の高さよりも小さい。そのため、補助ホルダ２４として第２補助ホルダ２４Ｂを用い、この第２補助ホルダ２４Ｂの第２装着凹部２４ｄに第６混練容器２３Ｆを装着することにより、第６混練容器２３Ｆの蓋２２が、容器ホルダ２１の周壁部２１ａの内面に接触することはない。   The sixth kneading container 23F shown in (c) of FIG. 4 is a container with a storage capacity of 10 g of pharmaceutical preparation, and the height from the bottom surface of the sixth kneading container 23F to the lower end of the lid 22 is the peripheral wall of the container holder 21. It is smaller than the height of the inner surface portion on the small inner diameter side of the inner surface of the portion 21a. Therefore, the second auxiliary holder 24B is used as the auxiliary holder 24, and the sixth kneading container 23F is mounted in the second mounting recess 24d of the second auxiliary holder 24B, so that the lid 22 of the sixth kneading container 23F is attached to the container holder. 21 does not contact the inner surface of the peripheral wall portion 21a.

また、医薬品製剤を含めた第６混練容器２３Ｆの重量は小さいため、第２補助ホルダ２４Ｂを重量調節部材として用いる。これにより、第２補助ホルダ２４Ｂを用いる第２使用形態において、容器ホルダ２１、第２補助ホルダ２４Ｂ、第６混練容器２３Ｆ、これに収納される医薬品製剤を含む総重量は、重量バランス調節手段４０を再調整する必要の無い設定範囲（例えば、１９０ｇ〜２５０g）内に設定されている。   Further, since the weight of the sixth kneading container 23F including the pharmaceutical preparation is small, the second auxiliary holder 24B is used as the weight adjusting member. Thereby, in the second usage pattern using the second auxiliary holder 24B, the total weight including the container holder 21, the second auxiliary holder 24B, the sixth kneading container 23F, and the pharmaceutical preparation stored in the container holder 21, the weight balance adjusting means 40 Is set within a setting range (for example, 190 g to 250 g) that does not require readjustment.

また、第２補助ホルダ２４Ｂは、第５混練容器２３Ｅと第６混練容器２３Ｆとに対して反転使用されるため、第２補助ホルダ２４Ｂの周壁部２４ａの外周面における上下の両端部には、指の掛かりを良くするための指掛け用溝２４ｅが形成されている。   Further, since the second auxiliary holder 24B is used in an inverted manner with respect to the fifth kneading container 23E and the sixth kneading container 23F, the upper and lower ends of the outer peripheral surface of the peripheral wall 24a of the second auxiliary holder 24B are A finger hooking groove 24e is formed to improve the hooking of the finger.

〔その他の実施形態〕
（１）公転駆動用モータ１１による容器ホルダ２１の公転回転速度は、公転回転時の遠心力で混練容器２３の外面が容器ホルダ２１の内面又は補助ホルダ２４の内面に押し付けられ、且つ、その押し付けられた混練容器２３の外面と容器ホルダ２１の内面又は補助ホルダ２４の内面との間での摩擦力で混練容器２３が容器ホルダ２１と一緒に自転する公転回転速度であれば、公転駆動用モータ１１を駆動制御する制御部において任意に設定することができる。 [Other Embodiments]
(1) The revolution speed of the container holder 21 by the revolution drive motor 11 is such that the outer surface of the kneading container 23 is pressed against the inner surface of the container holder 21 or the inner surface of the auxiliary holder 24 by the centrifugal force during the revolution rotation. If the revolution speed is such that the kneading container 23 rotates together with the container holder 21 by the frictional force between the outer surface of the kneading container 23 and the inner surface of the container holder 21 or the inner surface of the auxiliary holder 24, the motor for revolution drive 11 can be arbitrarily set in the control unit that drives and controls the motor 11.

（２）上述の実施形態では、混練容器２３としては、形態の異なる第１混練容器２３Ａ〜第６混練容器２３Ｆの６種類を例示したが、この６種類の形態に限定されるものではない。外径又は高さの少なくとも一方が異なる複数種類の混練容器２３であればよい。   (2) In the above-described embodiment, as the kneading container 23, six types of the first kneading container 23 </ b> A to the sixth kneading container 23 </ b> F having different forms are exemplified, but the present invention is not limited to these six kinds of forms. What is necessary is just the multiple types of kneading | mixing container 23 from which at least one of an outer diameter or height differs.

（３）上述の実施形態では、補助ホルダ２４として、図３に示す第１補助ホルダ２４Ａと図４に示す第２補助ホルダ２４Ｂとの２種類を例示したが、この２種類の形態に限定されるものではなく、１種類又は３種類以上の形態の補助ホルダ２４から構成してもよい。   (3) In the above-described embodiment, as the auxiliary holder 24, two types of the first auxiliary holder 24A shown in FIG. 3 and the second auxiliary holder 24B shown in FIG. 4 are illustrated, but the auxiliary holder 24 is limited to these two types. The auxiliary holder 24 may be composed of one type or three or more types.

（４）上述の実施形態では、公転駆動用電動モータ１１に連動された公転軸芯Ｙ１周りで駆動回転可能な回転体１２を枠状に構成したが、円盤状等に構成してもよい。   (4) In the above-described embodiment, the rotating body 12 that can be driven and rotated around the revolution axis Y1 interlocked with the electric motor 11 for revolution driving is configured in a frame shape, but may be configured in a disk shape or the like.

（５）上述の実施形態では、公転駆動用電動モータ１１を自転駆動手段３０の駆動源に構成したが、自転駆動手段３０用の専用の駆動源を設けてもよい。   (5) In the above-described embodiment, the revolution driving electric motor 11 is configured as the driving source of the rotation driving means 30, but a dedicated driving source for the rotation driving means 30 may be provided.

１１ 公転駆動手段（公転駆動用モータ）
１２ 回転体
２０ 容器ホルダ保持部
２１ 容器ホルダ
２２ 蓋
２３ 混練容器
２４ 補助ホルダ
２７ 弾性体
３０ 自転駆動手段
Ｓ 融通
Ｙ１ 公転軸芯
Ｙ２ 自転軸芯 11 Revolution drive means (Revolution drive motor)
DESCRIPTION OF SYMBOLS 12 Rotating body 20 Container holder holding part 21 Container holder 22 Cover 23 Kneading container 24 Auxiliary holder 27 Elastic body 30 Rotation drive means S Interchange Y1 Revolving shaft core Y2 Rotating shaft core

Claims (5)

公転駆動手段に連動された公転軸芯周りで駆動回転可能な回転体に、混練容器を脱着自在に収納する自転自在な容器ホルダが備えられ、前記容器ホルダを自転軸芯周りで駆動回転させる自転駆動手段が設けられている混練装置であって、
前記容器ホルダの内面と前記混練容器の外面との間に、前記容器ホルダに対する前記混練容器の径方向への移動を許容する融通を設け、前記公転駆動手段による前記容器ホルダの公転回転速度を、公転回転時の遠心力で前記混練容器の外面が前記容器ホルダの内面に押し付けられ、且つ、その押し付けられた前記混練容器の外面と前記容器ホルダの内面との間での摩擦力で前記混練容器が自転する公転回転速度に設定してある混練装置。 A rotating body that can be driven and rotated around the revolution axis linked to the revolution drive means is provided with a rotatable container holder that detachably accommodates the kneading container, and the rotation that drives and rotates the container holder around the rotation axis. A kneading apparatus provided with a driving means,
Provided between the inner surface of the container holder and the outer surface of the kneading container to allow the kneading container to move in the radial direction with respect to the container holder, and the revolution speed of the container holder by the revolution driving means, The outer surface of the kneading container is pressed against the inner surface of the container holder by centrifugal force during revolution rotation, and the kneading container is subjected to a frictional force between the pressed outer surface of the kneading container and the inner surface of the container holder. Is a kneading machine set to the revolution speed at which it rotates. 前記容器ホルダは、前記回転体に設けられた容器ホルダ保持部に対して脱着自在に構成されている請求項１記載の混練装置。   The kneading apparatus according to claim 1, wherein the container holder is configured to be detachable with respect to a container holder holding part provided in the rotating body. 前記混練容器は、外径、高さの少なくとも一方が異なる複数種類の蓋付き混練容器から構成され、前記容器ホルダには、前記混練容器をそれの蓋が前記容器ホルダの内面に接触しない位置に配置保持する補助ホルダが脱着自在に設けられている請求項１又は２記載の混練装置。   The kneading container is composed of a plurality of types of kneading containers with lids having different outer diameters and heights, and the kneading container is placed at a position where the lid does not contact the inner surface of the container holder. The kneading apparatus according to claim 1 or 2, wherein an auxiliary holder for arranging and holding is detachably provided. 前記容器ホルダの周壁部の内面には、当該内面よりも径方向内方に突出する弾性体が設けられている請求項１〜３のいずれか１項に記載の混練装置。   The kneading apparatus according to any one of claims 1 to 3, wherein an elastic body protruding radially inward from the inner surface is provided on an inner surface of the peripheral wall portion of the container holder. 前記補助ホルダの内面と前記混練容器の外面との間に前記融通が形成されている請求項３記載の混練装置。

The kneading apparatus according to claim 3, wherein the interchange is formed between an inner surface of the auxiliary holder and an outer surface of the kneading container.

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11179181A (en) * 1997-12-18 1999-07-06 Eme:Kk Planetary stirring and defoaming mixer
JP2000084388A (en) * 1998-09-14 2000-03-28 Kurabo Ind Ltd Stirring device and stirring
JP2006095403A (en) * 2004-09-29 2006-04-13 Watanabe Kk Vessel adapter for syringe
JP2008178850A (en) * 2007-01-24 2008-08-07 I K S:Kk Agitating and defoaming apparatus for material to be agitated
WO2009090859A1 (en) * 2008-01-16 2009-07-23 Sony Chemical & Information Device Corporation Stirring device, stirrer, and stirring method
JP2013094725A (en) * 2011-10-31 2013-05-20 Daido Kako Kk Kneader
JP2013173092A (en) * 2012-02-24 2013-09-05 Sharp Corp Mixing vessel, kneader, and method of kneading
JP2016097372A (en) * 2014-11-25 2016-05-30 株式会社マルコム Paste mix defoaming apparatus

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11179181A (en) * 1997-12-18 1999-07-06 Eme:Kk Planetary stirring and defoaming mixer
JP2000084388A (en) * 1998-09-14 2000-03-28 Kurabo Ind Ltd Stirring device and stirring
JP2006095403A (en) * 2004-09-29 2006-04-13 Watanabe Kk Vessel adapter for syringe
JP2008178850A (en) * 2007-01-24 2008-08-07 I K S:Kk Agitating and defoaming apparatus for material to be agitated
WO2009090859A1 (en) * 2008-01-16 2009-07-23 Sony Chemical & Information Device Corporation Stirring device, stirrer, and stirring method
JP2013094725A (en) * 2011-10-31 2013-05-20 Daido Kako Kk Kneader
JP2013173092A (en) * 2012-02-24 2013-09-05 Sharp Corp Mixing vessel, kneader, and method of kneading
JP2016097372A (en) * 2014-11-25 2016-05-30 株式会社マルコム Paste mix defoaming apparatus

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