JP2012219021A - メラニン産生抑制剤 - Google Patents
メラニン産生抑制剤 Download PDFInfo
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- JP2012219021A JP2012219021A JP2011083322A JP2011083322A JP2012219021A JP 2012219021 A JP2012219021 A JP 2012219021A JP 2011083322 A JP2011083322 A JP 2011083322A JP 2011083322 A JP2011083322 A JP 2011083322A JP 2012219021 A JP2012219021 A JP 2012219021A
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- Prior art keywords
- extract
- melanin production
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- production inhibitor
- extraction
- Prior art date
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- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 12
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- 239000000470 constituent Substances 0.000 description 5
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- 208000001382 Experimental Melanoma Diseases 0.000 description 3
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- PGSADBUBUOPOJS-UHFFFAOYSA-N neutral red Chemical compound Cl.C1=C(C)C(N)=CC2=NC3=CC(N(C)C)=CC=C3N=C21 PGSADBUBUOPOJS-UHFFFAOYSA-N 0.000 description 2
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- AHMIDUVKSGCHAU-UHFFFAOYSA-N Dopaquinone Natural products OC(=O)C(N)CC1=CC(=O)C(=O)C=C1 AHMIDUVKSGCHAU-UHFFFAOYSA-N 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- AHMIDUVKSGCHAU-LURJTMIESA-N L-dopaquinone Chemical compound [O-]C(=O)[C@@H]([NH3+])CC1=CC(=O)C(=O)C=C1 AHMIDUVKSGCHAU-LURJTMIESA-N 0.000 description 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
- 244000062730 Melissa officinalis Species 0.000 description 1
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- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
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- Cosmetics (AREA)
Abstract
【解決手段】本発明のメラニン産生抑制剤の有効成分として、マチルス抽出物、クスノハガシワ抽出物、ヒマラヤンラズベリー抽出物、アセンヤク抽出物、プルーン抽出物及びマツホド抽出物からなる群より選択される1種又は2種以上の抽出物を含有させる。
【選択図】なし
Description
本実施形態のメラニン産生抑制剤は、マチルス抽出物、クスノハガシワ抽出物、ヒマラヤンラズベリー抽出物、アセンヤク抽出物、プルーン抽出物及びマツホド抽出物からなる群より選択される1種又は2種以上の抽出物を有効成分として含有するものである。
上記各抽出物(試料1〜6)について、以下のようにしてB16メラノーマ細胞に対するメラニン産生抑制作用を試験した。
上記式において、Aは「試料無添加時の475nmにおける吸光度」を表し、Bは「被験試料添加時の475nmにおける吸光度」を表し、Cは「試料無添加時の540nmにおける吸光度」を表し、Dは「被験試料添加時の540nmにおける吸光度」を表す。
結果を表2に示す。
Claims (1)
- マチルス抽出物、クスノハガシワ抽出物、ヒマラヤンラズベリー抽出物、アセンヤク抽出物、プルーン抽出物及びマツホド抽出物からなる群より選択される1種又は2種以上の抽出物を有効成分として含有することを特徴とするメラニン産生抑制剤。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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JP2011083322A JP5896618B2 (ja) | 2011-04-05 | 2011-04-05 | メラニン産生抑制剤 |
Applications Claiming Priority (1)
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JP2011083322A JP5896618B2 (ja) | 2011-04-05 | 2011-04-05 | メラニン産生抑制剤 |
Publications (2)
Publication Number | Publication Date |
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JP2012219021A true JP2012219021A (ja) | 2012-11-12 |
JP5896618B2 JP5896618B2 (ja) | 2016-03-30 |
Family
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JP2011083322A Active JP5896618B2 (ja) | 2011-04-05 | 2011-04-05 | メラニン産生抑制剤 |
Country Status (1)
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JP (1) | JP5896618B2 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102988190A (zh) * | 2012-12-28 | 2013-03-27 | 广州市白云区新东方日用化工品厂 | 美白组合物及其应用 |
JP2016210714A (ja) * | 2015-05-01 | 2016-12-15 | 株式会社ナリス化粧品 | 選択的シミ改善剤 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS632913A (ja) * | 1986-06-20 | 1988-01-07 | Sansho Seiyaku Kk | 外用剤 |
JPS6483009A (en) * | 1987-09-25 | 1989-03-28 | Sansho Seiyaku Kk | Melanization inhibitory drug for external use |
JPH092967A (ja) * | 1995-06-16 | 1997-01-07 | Sanki Shoji Kk | チロシナーゼ活性阻害剤及びこれを含有する化粧料 |
JPH0930949A (ja) * | 1995-07-21 | 1997-02-04 | Shiseido Co Ltd | 美白用皮膚外用剤 |
JP2003146837A (ja) * | 2001-11-13 | 2003-05-21 | Maruzen Pharmaceut Co Ltd | 皮膚化粧料及び美容用飲食品 |
JP2006347926A (ja) * | 2005-06-14 | 2006-12-28 | Ichimaru Pharcos Co Ltd | ファゴサイトーシス抑制剤 |
JP2008273875A (ja) * | 2007-04-27 | 2008-11-13 | Maruzen Pharmaceut Co Ltd | 幹細胞増殖因子発現上昇抑制剤 |
JP2009084164A (ja) * | 2007-09-27 | 2009-04-23 | Septem Soken:Kk | 老化防止剤 |
-
2011
- 2011-04-05 JP JP2011083322A patent/JP5896618B2/ja active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS632913A (ja) * | 1986-06-20 | 1988-01-07 | Sansho Seiyaku Kk | 外用剤 |
JPS6483009A (en) * | 1987-09-25 | 1989-03-28 | Sansho Seiyaku Kk | Melanization inhibitory drug for external use |
JPH092967A (ja) * | 1995-06-16 | 1997-01-07 | Sanki Shoji Kk | チロシナーゼ活性阻害剤及びこれを含有する化粧料 |
JPH0930949A (ja) * | 1995-07-21 | 1997-02-04 | Shiseido Co Ltd | 美白用皮膚外用剤 |
JP2003146837A (ja) * | 2001-11-13 | 2003-05-21 | Maruzen Pharmaceut Co Ltd | 皮膚化粧料及び美容用飲食品 |
JP2006347926A (ja) * | 2005-06-14 | 2006-12-28 | Ichimaru Pharcos Co Ltd | ファゴサイトーシス抑制剤 |
JP2008273875A (ja) * | 2007-04-27 | 2008-11-13 | Maruzen Pharmaceut Co Ltd | 幹細胞増殖因子発現上昇抑制剤 |
JP2009084164A (ja) * | 2007-09-27 | 2009-04-23 | Septem Soken:Kk | 老化防止剤 |
Non-Patent Citations (1)
Title |
---|
田村 博明ら, 新 化粧品ハンドブック, JPN6014047519, 30 October 2006 (2006-10-30), pages 525 - 539, ISSN: 0002936373 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102988190A (zh) * | 2012-12-28 | 2013-03-27 | 广州市白云区新东方日用化工品厂 | 美白组合物及其应用 |
JP2016210714A (ja) * | 2015-05-01 | 2016-12-15 | 株式会社ナリス化粧品 | 選択的シミ改善剤 |
Also Published As
Publication number | Publication date |
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JP5896618B2 (ja) | 2016-03-30 |
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