JP2011522552A - 化学的に修飾されたｒｎａの酵素的合成のための方法 - Google Patents

化学的に修飾されたｒｎａの酵素的合成のための方法 Download PDF

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JP2011522552A
JP2011522552A JP2011512963A JP2011512963A JP2011522552A JP 2011522552 A JP2011522552 A JP 2011522552A JP 2011512963 A JP2011512963 A JP 2011512963A JP 2011512963 A JP2011512963 A JP 2011512963A JP 2011522552 A JP2011522552 A JP 2011522552A
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Prior art keywords
triphosphate
rna
chemically modified
dsrna
rdrp
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ジャックス・ロハイエム
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リボックス・ゲーエムベーハー
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2011512963A 2008-06-13 2009-06-09 化学的に修飾されたｒｎａの酵素的合成のための方法 Pending JP2011522552A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08010829 2008-06-13
EP08010829.3 2008-06-13
PCT/EP2009/057119 WO2009150156A1 (fr) 2008-06-13 2009-06-09 Procédé permettant la synthèse enzymatique de l'arn modifié chimiquement

Publications (1)

Publication Number Publication Date
JP2011522552A true JP2011522552A (ja) 2011-08-04

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Family Applications (1)

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JP2011512963A Pending JP2011522552A (ja) 2008-06-13 2009-06-09 化学的に修飾されたｒｎａの酵素的合成のための方法

Country Status (4)

Country Link
US (1) US20110053226A1 (fr)
EP (1) EP2235177B1 (fr)
JP (1) JP2011522552A (fr)
WO (1) WO2009150156A1 (fr)

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WO2013040116A1 (fr) 2011-09-13 2013-03-21 Monsanto Technology Llc Procédés et compositions de lutte contre les mauvaises herbes
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
UA116089C2 (uk) 2011-09-13 2018-02-12 Монсанто Текнолоджи Ллс Спосіб та композиція для боротьби з бур'янами (варіанти)
EP2773760B2 (fr) 2011-10-31 2020-11-04 RiboxX GmbH Arn double brin pour l'immunostimulation
WO2013097965A1 (fr) 2011-12-30 2013-07-04 Riboxx Gmbh Arn bicaténaire contenant un triphosphate pour l'immunostimulation
CA2873828A1 (fr) 2012-05-24 2013-11-28 A.B. Seeds Ltd. Arn a double brin nue interferent en agissant sur les molecules cibles dans des graines de plantes
UY35252A (es) 2013-01-01 2014-07-31 Seeds Ltd Ab MÉTODOS PARA INTRODUCIR dsRNA EN SEMILLAS DE PLANTAS PARA MODULAR LA EXPRESIÓN GENÉTICA
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
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US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
PL3030663T3 (pl) 2013-07-19 2020-04-30 Monsanto Technology Llc Kompozycje i sposoby kontroli leptinotarsa
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
RU2694950C2 (ru) 2013-11-04 2019-07-18 Монсанто Текнолоджи Ллс Композиции и способы для борьбы с членистоногими паразитами и заражениями вредителями
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
US10334848B2 (en) 2014-01-15 2019-07-02 Monsanto Technology Llc Methods and compositions for weed control using EPSPS polynucleotides
CN106413390B (zh) 2014-04-01 2019-09-27 孟山都技术公司 用于控制虫害的组合物和方法
CA2953347A1 (fr) 2014-06-23 2015-12-30 Monsanto Technology Llc Compositions et methodes de regulation de l'expression genetique par interference par arn
US11807857B2 (en) 2014-06-25 2023-11-07 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
RU2021123470A (ru) 2014-07-29 2021-09-06 Монсанто Текнолоджи Ллс Композиции и способы борьбы с насекомыми-вредителями
WO2016112963A1 (fr) 2015-01-13 2016-07-21 Riboxx Gmbh Administration de biomolécules dans des cellules
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EP3302053B1 (fr) 2015-06-02 2021-03-17 Monsanto Technology LLC Compositions et procédés pour l'administration d'un polynucléotide dans une plante
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WO2017121494A1 (fr) 2016-01-15 2017-07-20 Riboxx Gmbh Nucléotides, oligonucléotides et polynucléotides immunostimuleurs courts 5'-triphosphatés
WO2022189861A1 (fr) 2021-03-08 2022-09-15 Tollys Conjugués d'hydrates de carbone de ligands tlr3 et leurs utilisations

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Publication number Publication date
EP2235177A1 (fr) 2010-10-06
EP2235177B1 (fr) 2012-07-18
WO2009150156A1 (fr) 2009-12-17
US20110053226A1 (en) 2011-03-03

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