JP2011200469A - Intraocular lens insertion implement - Google Patents

Intraocular lens insertion implement Download PDF

Info

Publication number
JP2011200469A
JP2011200469A JP2010071193A JP2010071193A JP2011200469A JP 2011200469 A JP2011200469 A JP 2011200469A JP 2010071193 A JP2010071193 A JP 2010071193A JP 2010071193 A JP2010071193 A JP 2010071193A JP 2011200469 A JP2011200469 A JP 2011200469A
Authority
JP
Japan
Prior art keywords
intraocular lens
liquid
eye
insertion device
plunger
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010071193A
Other languages
Japanese (ja)
Other versions
JP5570265B2 (en
JP2011200469A5 (en
Inventor
Shinji Nagasaka
信司 長坂
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nidek Co Ltd
Original Assignee
Nidek Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nidek Co Ltd filed Critical Nidek Co Ltd
Priority to JP2010071193A priority Critical patent/JP5570265B2/en
Publication of JP2011200469A publication Critical patent/JP2011200469A/en
Publication of JP2011200469A5 publication Critical patent/JP2011200469A5/ja
Application granted granted Critical
Publication of JP5570265B2 publication Critical patent/JP5570265B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1662Instruments for inserting intraocular lenses into the eye
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1662Instruments for inserting intraocular lenses into the eye
    • A61F2/167Instruments for inserting intraocular lenses into the eye with pushable plungers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1662Instruments for inserting intraocular lenses into the eye
    • A61F2/1675Instruments for inserting intraocular lenses into the eye with a lubricated inner surface, e.g. the lubricant being coated on the inner surface or being injected through a port

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

PROBLEM TO BE SOLVED: To provide an intraocular lens insertion implement which allows the intraocular lens to be set inside an eye through the use of the liquid such as a physiological salt solution without using a viscoelastic substance and suitably adjust an intraocular lens extruding action and a liquid supply action.SOLUTION: The intraocular lens insertion implement includes: an insertion part to be inserted to an incision wound arranged in the eyeball in order to insert the deformable intraocular lens to an eye; a tubular body having the insertion part at the distal end; and a plunger which is arranged inside the tubular body so as to be movable in front and rear directions in order to extrude the intraocular lens. The tubular body includes: a storage part for storing the liquid, wherein a passage for passing the liquid toward the insertion part is formed; a supply port for supplying the liquid to the storage part from an external part; and an extruder for extruding the liquid inside the storage part toward the insertion part, which is arranged in the tubular body independently from the extrusion of the plunger.

Description

本発明は、眼内レンズを眼内に挿入するための眼内レンズ挿入器具に関する。   The present invention relates to an intraocular lens insertion device for inserting an intraocular lens into the eye.

従来、白内障の手術方法の一つとして水晶体を摘出した後、水晶体の代わりとして折り曲げ可能な軟性の光学部と,眼内にて光学部を固定保持させるためのループと呼ばれる支持部とで構成される眼内レンズを挿入する手法が一般的に用いられている。折り曲げ可能な眼内レンズの挿入には、インジェクターと呼ばれる眼内レンズ挿入器具が用いられる。インジェクターは内部に置かれた眼内レンズをプランジャーと呼ばれる押出棒にて、挿入部の先端に向けて押し出し、先端から送出させる。(例えば、特許文献1参照)。このような従来のインジェクターは、押し出される眼内レンズの滑りを良くするために、押し出し前に粘弾性物質が内部に注入され、眼内レンズの押し出しを好適に行うようにしている。また、粘弾性物質は水晶体が取り除かれた嚢を膨らませ、眼内レンズを嚢内に設置し易くするためにも用いられる。   Conventionally, it is composed of a soft optical part that can be bent after the lens is extracted as one of the surgical methods for cataract and a support part called a loop for fixing and holding the optical part in the eye. A method of inserting an intraocular lens is generally used. An intraocular lens insertion device called an injector is used to insert a foldable intraocular lens. The injector pushes the intraocular lens placed inside with an extrusion rod called a plunger toward the distal end of the insertion portion, and sends it out from the distal end. (For example, see Patent Document 1). In such a conventional injector, in order to improve the sliding of the intraocular lens to be pushed out, a viscoelastic substance is injected into the inside before pushing out, so that the intraocular lens is pushed out suitably. The viscoelastic material is also used to inflate the sac from which the crystalline lens has been removed and to facilitate the placement of the intraocular lens in the sac.

また、一方で粘弾性物質の代わりに生理食塩水等の液体(眼灌流液)を用いることにより、安価に手間なく押し出し作業を行うことのできるインジェクターが提案されている。このようなインジェクターは、例えば、押出軸(プランジャー)の基端からインジェクター内部に液体を注入してインジェクター先端から液体を送り出す機構を備えるものや、インジェクター内部に液体を貯留するためのタンク部を備え、プランジャーの押し出しとともに液体を先端から送り出すものが知られている(特許文献2,特許文献3 参照)。このような液体を用いたインジェクターは眼内にて水晶体が取り除かれた嚢を生理食塩水等の液体を用いて膨らませたり、インジェクター内における眼内レンズの滑りを良くすることが可能である。   On the other hand, there has been proposed an injector capable of performing extrusion work at low cost without using a liquid (eye perfusion liquid) such as physiological saline instead of a viscoelastic substance. Such an injector includes, for example, a mechanism having a mechanism for injecting liquid from the proximal end of the extrusion shaft (plunger) into the injector and feeding the liquid from the distal end of the injector, or a tank part for storing the liquid inside the injector. It is known that a liquid is sent out from the tip together with pushing out a plunger (see Patent Document 2 and Patent Document 3). An injector using such a liquid can inflate a sac from which the lens has been removed in the eye using a liquid such as physiological saline, or improve the slipping of the intraocular lens in the injector.

特開2006−333981号公報JP 2006-333981 A 特開2008−307394号公報JP 2008-307394 A 特開2009−291250号公報JP 2009-291250 A

しかしながら、特許文献2の挿入器具では、液を供給する装置をインジェクターに接続した状態で眼内レンズを挿入させる必要があり使い勝手が悪い。また、特許文献3の挿入器具においては、眼内レンズの押し出し動作に基づいて眼内への液の供給も行うため、眼内への液体の供給中に眼内レンズも押されてしまう可能性がある。   However, in the insertion instrument of Patent Document 2, it is necessary to insert an intraocular lens in a state where a device for supplying a liquid is connected to an injector, which is inconvenient. In addition, since the insertion device of Patent Document 3 also supplies the liquid into the eye based on the pushing operation of the intraocular lens, the intraocular lens may be pushed during the supply of the liquid into the eye. There is.

本発明は、上記従来技術の問題点に鑑み、粘弾性物質を用いることなく生理食塩水等の液体を用いて眼内レンズを眼内に設置することができ、好適に眼内レンズの押出動作と液体の供給動作とを調節することができる眼内レンズ挿入器具を提供することを技術課題とする。   In view of the above-mentioned problems of the prior art, the present invention can place an intraocular lens in the eye using a liquid such as physiological saline without using a viscoelastic substance, and preferably pushes out the intraocular lens. It is an object of the present invention to provide an intraocular lens insertion device capable of adjusting the liquid supply operation.

上記課題を解決するために、本発明は以下のような構成を備えることを特徴とする。   In order to solve the above problems, the present invention is characterized by having the following configuration.

(1) 変形可能な眼内レンズを眼内に挿入するために眼球に設けられた切開創に挿入する挿入部と、該挿入部を先端に持つ筒部本体と、眼内レンズを押し出すために前記筒部本体内部に前後方向に移動可能に設けられるプランジャーとを有する眼内レンズ挿入器具において、前記筒部本体には、液体を貯留するための貯留部であって,前記挿入部に向けて前記液体を通すための通路が形成される貯留部と、該貯留部に外部から前記液体を供給するための供給口と、前記貯留部内の液体を前記挿入部に向けて押し出すための押出手段であって,前記プランジャーの押し出しとは別に独立して前記筒部本体に設けられる押出手段と、が設けられていることを特徴とする。
(2) (1)の眼内レンズ挿入器具において、前記貯留部は前記プランジャーが挿通する前記筒部本体内領域とは区分けされた異なる領域に設けられていることを特徴とする。
(3) (2)の眼内レンズ挿入器具は、さらに前記貯留部内の液体を外部に排出するための排出口が前記貯留部から前記挿入部先端に至るまでの間に設けられていることを特徴とする。
(4) (1)〜(3)の眼内レンズ挿入器具において、前記挿入部の内壁には水溶性の潤滑剤がコーティングされていることを特徴とする。
(1) To insert a deformable intraocular lens into an incision provided in an eyeball to insert the deformable intraocular lens, a cylindrical body having the insertion part at the tip, and an intraocular lens In the intraocular lens insertion device having a plunger that is movably provided in the front-rear direction inside the tubular body, the tubular body is a storage portion for storing a liquid, and is directed toward the insertion portion. A storage part in which a passage for passing the liquid is formed, a supply port for supplying the liquid to the storage part from the outside, and an extrusion means for extruding the liquid in the storage part toward the insertion part And the extrusion means provided in the said cylinder part main body independently of the extrusion of the said plunger is provided, It is characterized by the above-mentioned.
(2) In the intraocular lens insertion device according to (1), the storage portion is provided in a different region separated from the region in the cylinder main body through which the plunger is inserted.
(3) In the intraocular lens insertion device according to (2), a discharge port for discharging the liquid in the storage part to the outside is further provided between the storage part and the distal end of the insertion part. Features.
(4) In the intraocular lens insertion device according to any one of (1) to (3), a water-soluble lubricant is coated on the inner wall of the insertion portion.

本発明によれば、粘弾性物質を用いることなく生理食塩水等の液体を用いて眼内レンズを眼内に設置することができ、好適に眼内レンズの押出動作と液体の供給動作とを調節することができる。   According to the present invention, an intraocular lens can be placed in the eye using a liquid such as physiological saline without using a viscoelastic substance, and preferably an intraocular lens push-out operation and a liquid supply operation are performed. Can be adjusted.

以下に本発明の実施形態を図面に示しながら説明する。図1は眼内レンズ10の構成を示した図であり、図1(a)は眼内レンズ10の正面図、図1(b)は眼内レンズ10の側面図である。眼内レンズ10は所定の屈折力を有する光学部11と、光学部11を眼内で支持するための一対の支持部12とから構成される。光学部11は、HEMA(ヒドロキシエチルメタクリレート)等の単体、アクリル酸エステルとメタクリル酸エステルの複合材料等、従来、折り曲げ可能な軟性の眼内レンズに用いられている材料から形成されている。また、支持部12はPMMA(ポリメチルメタクリレート)、ポリプロピレン等の従来眼内レンズの支持部として用いられる材料にて形成される。   Embodiments of the present invention will be described below with reference to the drawings. FIG. 1 is a diagram illustrating a configuration of the intraocular lens 10, FIG. 1A is a front view of the intraocular lens 10, and FIG. 1B is a side view of the intraocular lens 10. The intraocular lens 10 includes an optical unit 11 having a predetermined refractive power and a pair of support units 12 for supporting the optical unit 11 in the eye. The optical unit 11 is formed of a material conventionally used for a flexible intraocular lens that can be bent, such as a simple substance such as HEMA (hydroxyethyl methacrylate), or a composite material of acrylic ester and methacrylic ester. Moreover, the support part 12 is formed with the material used as a support part of conventional intraocular lenses, such as PMMA (polymethylmethacrylate) and a polypropylene.

なお、図1では、光学部11と,先端が自由端とされ細いループ形状(C字状、J字状)からなる支持部12とを別々に作成しておき、その後、一体化させることで得られる3ピース型の眼内レンズが例に示されている。これ以外にも、眼内レンズ10としては、前述した眼内レンズ材料を使用して、光学部11と支持部12とが、切削加工、モールディング加工等で一体的に形成される1ピース型の眼内レンズを用いることができる。   In addition, in FIG. 1, the optical part 11 and the support part 12 which makes the front-end | tip free end and consists of a thin loop shape (C shape, J shape) are produced separately, and are integrated after that. The resulting three-piece intraocular lens is shown as an example. In addition to this, the intraocular lens 10 is a one-piece type in which the optical part 11 and the support part 12 are integrally formed by cutting, molding, or the like using the above-described intraocular lens material. An intraocular lens can be used.

図2は本実施の形態で使用する眼内レンズ挿入器具100の外観を示した概略外観図であり、図2(a)は眼内レンズ挿入器具100の斜視図、図2(b)は側方から見た状態、図2(c)は下方から見た状態を示している。図3は眼内レンズ挿入器具100の内部構成を示した模式図である。眼内レンズ挿入器具100は、眼内レンズ10を内部に載置する挿入部110(以下、カートリッジと記す)と、筒部本体120と、筒部本体120に対して前後方向に移動可能に取りつけられる押出部材130,140から構成されている。本実施形態では押出部材130は眼内レンズ10を挿入筒の先端111aから押し出すために用いられ、押出部材140は後述する液体を眼内に供給するために用いられる。挿入部110には、先端に向かうに従いその内径が徐々に小さく(細く)なる領域を有したテーパ形状を有する挿入筒111が設けられている。挿入部110内部に載置される眼内レンズ10は、挿入筒111の内部を通ることにより小さく折り曲げられ、その先端111aから送出される。なお、挿入部110(挿入筒111)の内壁には親水性の潤滑剤がコーティングされている。   FIG. 2 is a schematic external view showing the external appearance of the intraocular lens insertion device 100 used in the present embodiment. FIG. 2 (a) is a perspective view of the intraocular lens insertion device 100, and FIG. FIG. 2C shows a state seen from below, as viewed from below. FIG. 3 is a schematic diagram showing the internal configuration of the intraocular lens insertion device 100. The intraocular lens insertion device 100 is attached to an insertion part 110 (hereinafter referred to as a cartridge) on which the intraocular lens 10 is placed, a cylinder body 120, and a cylinder body 120 that can move in the front-rear direction. It is comprised from the extrusion members 130 and 140 manufactured. In this embodiment, the pushing member 130 is used to push out the intraocular lens 10 from the distal end 111a of the insertion tube, and the pushing member 140 is used to supply a liquid to be described later into the eye. The insertion portion 110 is provided with an insertion cylinder 111 having a tapered shape having a region where the inner diameter gradually decreases (thinner) toward the distal end. The intraocular lens 10 placed inside the insertion portion 110 is bent slightly by passing through the inside of the insertion tube 111, and is sent out from the distal end 111a. The inner wall of the insertion part 110 (insertion cylinder 111) is coated with a hydrophilic lubricant.

また、筒部本体120の内部空間は、上下方向に2つに区分けされており、一方の空間120aは、押出部材130が挿通する通路とされ、挿入部110の通路と連結している。また、もう一方の空間は生理食塩水等の液体(眼灌流液)を貯留するための貯留部120bとして用いられる。なお、貯留部120bに貯留される液体は、白内障手術において水晶体を取り除いた後に嚢を膨らませる等の前房確保や挿入部110内に置かれる眼内レンズの押し出しを行いやすくために用いられる。このため、貯留部120bを形成する空間は、患者眼の前房確保等の手術時に必要とされる量の液体を貯留するために十分な容積を有している。なお、筒部本体120内の空間120aと貯留部120bとは筒部本体120内に設けられた内壁wを介して区分けされているが、内壁wの一部には貯留部120bに貯留された液体を挿入部110の通路に導くための開口部121が設けられている。開口部121は貯留部120bに溜められている液体を挿入部110内の通路に通すことのできる箇所に形成されていればよい。なお、本実施形態では開口部121は貯留部120bの先端付近に形成されているものとしている。   In addition, the internal space of the cylinder main body 120 is divided into two in the vertical direction, and one space 120a is a passage through which the pushing member 130 is inserted, and is connected to the passage of the insertion portion 110. The other space is used as a reservoir 120b for storing a liquid (eye perfusate) such as physiological saline. The liquid stored in the storage unit 120b is used for facilitating securing the anterior chamber such as inflating the sac after removing the lens in cataract surgery and pushing out the intraocular lens placed in the insertion unit 110. For this reason, the space which forms the storage part 120b has a sufficient volume for storing the amount of liquid required at the time of surgery such as securing the anterior chamber of the patient's eye. In addition, although the space 120a and the storage part 120b in the cylinder part main body 120 are divided through the inner wall w provided in the cylinder part main body 120, a part of the inner wall w is stored in the storage part 120b. An opening 121 for guiding the liquid to the passage of the insertion portion 110 is provided. The opening part 121 should just be formed in the location which can let the liquid stored in the storage part 120b pass through the channel | path in the insertion part 110. FIG. In the present embodiment, the opening 121 is formed near the tip of the storage portion 120b.

押出部材130は、眼内レンズ10の押出時に術者により押圧される押圧部131と、押圧部131に接続され,押出部材130が空間120aを移動する軸基部132と、軸基部132の先端に接続され,軸基部132よりも細い径で形成された押出棒133と、押出棒133の先端に形成され,眼内レンズ10の光学部11(側面)に当接される先端部134とから構成される。なお、押出棒133の長さは押出部材130を空間120a内で押し込んだときに、押出棒133の先端がカートリッジ110の先端111aから十分に出るような長さとされる。   The pushing member 130 is connected to the pressing portion 131 that is pressed by the operator when the intraocular lens 10 is pushed, the shaft base 132 that is moved by the pushing member 130 in the space 120a, and the tip of the shaft base 132. The push rod 133 is connected and formed with a diameter smaller than that of the shaft base portion 132, and the tip portion 134 is formed at the tip of the push rod 133 and is in contact with the optical portion 11 (side surface) of the intraocular lens 10. Is done. Note that the length of the push rod 133 is set such that when the push member 130 is pushed into the space 120 a, the tip of the push rod 133 is sufficiently protruded from the tip 111 a of the cartridge 110.

押出部材140は、液体の押出時に術者により押圧される押圧部141と、押圧部141に接続され,貯留部120b内をスライド可能であると共に、少なくともその先端の外径が貯留部120bの内径と略一致する大きさで形成された押出棒142とから構成されている。また、押出棒142の軸方向の長さは,押出部材140を貯留部120b内で押し込んだときに、少なくとも手術時に必要な量の液体が挿入部110の先端から送出されるだけの長さで形成されることが好ましい。   The extruding member 140 is connected to the pressing portion 141 that is pressed by the operator when the liquid is extruded, and can be slid within the storage portion 120b, and at least the outer diameter of the distal end thereof is the inner diameter of the storage portion 120b. And an extrusion rod 142 formed with a size that substantially coincides with. Further, the length of the push rod 142 in the axial direction is a length that allows at least a necessary amount of liquid to be delivered from the distal end of the insertion portion 110 when the push member 140 is pushed into the storage portion 120b. Preferably it is formed.

また、以上のような押出棒142は、少なくともその先端部分がゴム等の弾性・復元力を有する素材にて形成されると、より押出棒142と貯留部120bの内壁との密着状態を好適に維持することができるようになる。更に、本実施形態では押出棒142全体の外径が貯留部120bの内壁と密着するように長手方向に一様に形成されているが、これに限られるものではない。例えば、押出棒142の先端のみが貯留部120bの内径と略一致されるように形成されていても良い(その他の部分は貯留部120bの内径よりも小さく形成されていても良い)。つまり、押出手段140は、前後方向に移動することによって貯留部120bの容積を変化させ、貯留部120bに溜められた液体を挿入部110へと押し出すことの出来る形状(構成)となっていれば良い。   Further, when the push-out rod 142 as described above is formed of a material having elasticity / restoring force such as rubber at least at the tip portion thereof, the close-contact state between the push-out rod 142 and the inner wall of the storage portion 120b is more preferable. Will be able to maintain. Furthermore, in the present embodiment, the outer diameter of the entire push rod 142 is uniformly formed in the longitudinal direction so as to be in close contact with the inner wall of the reservoir 120b, but is not limited thereto. For example, only the tip of the push rod 142 may be formed so as to substantially coincide with the inner diameter of the storage part 120b (other parts may be formed smaller than the inner diameter of the storage part 120b). That is, if the extrusion means 140 has a shape (configuration) that can move in the front-rear direction to change the volume of the storage unit 120b and push the liquid stored in the storage unit 120b to the insertion unit 110. good.

また、貯留部120bの側面(筒部本体120上)には、外部から液体を貯留部120b内へと供給するための供給口122が形成されている。なお、供給口122は液体を注入させるための器具先端を差し入れることができる程度の大きさにて形成される事が好ましい。液体を注入させる器具としては生理食塩水が充填された注射器や白内障手術で一般的に用いられ灌流液を眼内に供給することのできる超音波乳化吸引装置のハンドピースの先端を差し入れることができる程度に狭い開口に形成される事が好ましい。   Further, a supply port 122 for supplying liquid from the outside into the storage unit 120b is formed on the side surface (on the cylinder body 120) of the storage unit 120b. In addition, it is preferable that the supply port 122 is formed in a size that can insert a tip of an instrument for injecting liquid. As a device for injecting a liquid, it is possible to insert a tip of a handpiece of a syringe filled with physiological saline or an ultrasonic emulsification suction device which is generally used in cataract surgery and can supply a perfusate into the eye. It is preferable to form the opening as narrow as possible.

また、本実施形態では、供給口122は押出部材140が設けられた基端側に形成されている。このようにすると、押出部材140を予め基端側へと引き出して、供給口122が貯留部120bと繋がるようにしておき、供給口122から液体を入れた後に、押出部材140の先端が供給口122を越える程度に前進させておくことにより、供給口122からの液体の流出を抑えることができる。   In the present embodiment, the supply port 122 is formed on the base end side where the push member 140 is provided. In this way, the push-out member 140 is pulled out to the base end side in advance so that the supply port 122 is connected to the storage part 120b, and after the liquid is introduced from the supply port 122, the tip of the push-out member 140 is connected to the supply port. By moving forward beyond the range 122, the outflow of liquid from the supply port 122 can be suppressed.

なお、眼内レンズ挿入器具100の供給口122の形成位置は、上記の構成に限られるものではない。例えば、供給口122は貯留部120bの外側(筒部本体120上)に形成されていれば良く、その形成位置は基端側から離れていても良い。なお、供給口122が基端側から離れている場合には、眼内レンズの押出時に術者の指で供給口122を押さえる等で液体の液漏れを防ぐことができる。なお、貯留部120b内に供給口122から液体を供給後、ゴム栓等の蓋部材を用いて供給口を塞ぐようにすることもできる。   The formation position of the supply port 122 of the intraocular lens insertion device 100 is not limited to the above configuration. For example, the supply port 122 should just be formed in the outer side (on the cylinder part main body 120) of the storage part 120b, and the formation position may be separated from the base end side. In addition, when the supply port 122 is away from the proximal end side, liquid leakage can be prevented by pressing the supply port 122 with the operator's finger when the intraocular lens is pushed out. In addition, after supplying the liquid from the supply port 122 into the reservoir 120b, the supply port may be closed using a lid member such as a rubber plug.

また、本実施形態では、押出部材130の押圧部131は押出部材140の押圧部141よりも後ろ側に位置するように形成されているとともに、押圧部131一部分が押出部材140の移動軸上にかかるように形成されている。このような構成により、液体のみを患者眼内に注入するときは押出部材140を単独で使用でき、眼内レンズ10を押し出す際には両押出部材130,140を一体的に使用することができる。このため、眼内レンズ10を眼内に挿入する段階で灌流液が必要となったときに、術者の使い勝手を向上させることができる。   In the present embodiment, the pressing portion 131 of the pushing member 130 is formed so as to be positioned behind the pushing portion 141 of the pushing member 140, and a part of the pushing portion 131 is on the moving axis of the pushing member 140. It is formed as such. With such a configuration, the pushing member 140 can be used alone when only the liquid is injected into the patient's eye, and the pushing members 130 and 140 can be used integrally when pushing the intraocular lens 10. . For this reason, when a perfusate is needed at the stage of inserting the intraocular lens 10 into the eye, the convenience of the operator can be improved.

次に、以上のような構成を備える眼内レンズ挿入器具100による眼内レンズ10の押出動作を説明する。図4は、眼内レンズ挿入器具100の押出動作を説明する模式的断面図である。はじめに、術者(使用者)は、鑷子等を用いて眼内レンズ10を挿入部110内の所定位置に置き、押出部材130及び押出部材140をそれぞれ筒部本体20の基端側へと引き出しておく。   Next, the pushing operation of the intraocular lens 10 by the intraocular lens insertion device 100 having the above configuration will be described. FIG. 4 is a schematic cross-sectional view for explaining the push-out operation of the intraocular lens insertion device 100. First, the operator (user) places the intraocular lens 10 at a predetermined position in the insertion portion 110 using a lever or the like, and pulls out the pushing member 130 and the pushing member 140 to the proximal end side of the cylindrical portion main body 20, respectively. Keep it.

次に、術者は貯留部120bを生理食塩水等の液体で満たすため、生理食塩水が充填された注射器の先端や灌流液を眼内に供給することのできる超音波乳化吸引装置のハンドピースの先端を供給口122に差し入れる。そして、所定の注入操作を行うことにより貯留部120b内に液体pfを十分に貯留させる。このとき、挿入筒111先端から液体が少しこぼれる程度まで液体を供給することが好ましい。液体が挿入部110内を通ることにより、挿入筒111内壁にコーティングされている潤滑剤が溶け、眼内レンズ10が通過する通路の滑りが良くなる。   Next, since the surgeon fills the reservoir 120b with a liquid such as physiological saline, the tip of a syringe filled with physiological saline or a handpiece of an ultrasonic emulsification and suction device that can supply perfusate into the eye Is inserted into the supply port 122. And liquid pf is fully stored in the storage part 120b by performing predetermined | prescribed injection | pouring operation. At this time, it is preferable to supply the liquid to the extent that the liquid spills slightly from the tip of the insertion tube 111. As the liquid passes through the insertion portion 110, the lubricant coated on the inner wall of the insertion cylinder 111 is melted, and slipping of the passage through which the intraocular lens 10 passes is improved.

図4(a)に示すように、貯留部120bに液体pfが貯留されたら、術者は押圧部141を若干押して、押出棒142によって供給口122を塞ぐ。これにより、供給口122からの液体pfの漏出することが抑えられる。以上のように眼内レンズ挿入器具100の用意ができたら、術者は患者眼の眼内圧を所定の圧力に維持して球形状を確保し、水晶体が取り除かれた嚢を膨らませる(前房確保する)ために、患者眼に形成された切開創にカートリッジ110の先端111を差し入れる。そして、図4(b)に示すように、押圧部141を押し、押出棒142によって貯留部120bの容積を狭めることによって貯留部120b内の液体pfを開口部121から挿入部110側に押し出し先端部111aから眼内に流入させる。   As shown in FIG. 4A, when the liquid pf is stored in the storage unit 120 b, the operator presses the pressing unit 141 slightly and closes the supply port 122 with the push-out rod 142. Thereby, leakage of the liquid pf from the supply port 122 is suppressed. When the intraocular lens insertion device 100 is prepared as described above, the surgeon maintains the intraocular pressure of the patient's eye at a predetermined pressure to ensure a spherical shape and inflates the sac from which the crystalline lens has been removed (anterior chamber). To secure) the tip 111 of the cartridge 110 is inserted into an incision formed in the patient's eye. Then, as shown in FIG. 4B, the pressing portion 141 is pushed, and the volume of the storage portion 120b is reduced by the push rod 142, thereby pushing the liquid pf in the storage portion 120b from the opening 121 to the insertion portion 110 side. It flows into the eye from the part 111a.

患者眼に液体pfが充填されて眼球(嚢)が十分に膨らんだ状態で、眼内レンズ100を眼内へと挿入させる。図4(c)に示すように、空間120a内で押出部材130が押されることによって、先端部134が光学部11の側面に当接される。この状態から、更に押出部材130が押し込まれていくと、眼内レンズ10が挿入筒111内に入り、挿入部111の内壁面に沿って、折り曲げられていく(丸め込まれていく)。   The intraocular lens 100 is inserted into the eye while the patient's eye is filled with the liquid pf and the eyeball (sac) is sufficiently expanded. As illustrated in FIG. 4C, the push-out member 130 is pushed in the space 120 a, so that the distal end portion 134 comes into contact with the side surface of the optical unit 11. When the push-out member 130 is further pushed from this state, the intraocular lens 10 enters the insertion tube 111 and is bent (rounded) along the inner wall surface of the insertion portion 111.

ところで、術者は眼内レンズ10を押し出しながら、眼内レンズ10の取り付け位置をより正確に決定させるために、切開創から入れられた挿入筒111の位置の調節を行うことがある。これにより、眼内の液体が一部外部に出てしまうことがある。この場合、本実施形態では、術者が押出部材140を押して液体pfを眼内に注入させることで、再び眼内の形状(内圧)を適切に保つことができるようになる。押圧部141が押されると、挿入部110の先端111aから液体pfが眼内へと流入する。この時、押出部材130の先端134が押し出し途中の眼内レンズ10に当接されているが、押出部材130と液体を押し出すための押出部材140とは各々独立しているため、術者は眼内レンズ10の押し出しの状態を変えることなく、液体pfのみを押し出すことができる。   By the way, the operator may adjust the position of the insertion tube 111 inserted from the incision in order to more accurately determine the attachment position of the intraocular lens 10 while pushing out the intraocular lens 10. Thereby, a part of the liquid in the eye may come out. In this case, in this embodiment, the surgeon can push the pusher member 140 to inject the liquid pf into the eye, so that the intraocular shape (internal pressure) can be kept appropriate again. When the pressing part 141 is pressed, the liquid pf flows from the distal end 111a of the insertion part 110 into the eye. At this time, the distal end 134 of the pushing member 130 is in contact with the intraocular lens 10 being pushed out. However, since the pushing member 130 and the pushing member 140 for pushing out the liquid are independent of each other, Only the liquid pf can be pushed out without changing the pushing state of the inner lens 10.

前房確保された状態で、眼内での眼内レンズ10の取り付け位置が定まったら、術者は押出部材130によって眼内レンズ10を眼内へと押し出す。これにより、先端111aから眼内レンズ10が眼内へと押し出され、光学部11が眼内で開放されると共に、支持部12が眼内から加えられる応力によって嚢に沿って配置され、眼内レンズ10が眼内で好適に保持されるようになる。   When the attachment position of the intraocular lens 10 is determined in the eye while the anterior chamber is secured, the operator pushes the intraocular lens 10 into the eye by the pushing member 130. As a result, the intraocular lens 10 is pushed into the eye from the tip 111a, the optical part 11 is opened in the eye, and the support part 12 is arranged along the sac by the stress applied from inside the eye. The lens 10 is suitably held in the eye.

以上のように、眼内レンズを押し出すための押出部材と液体を押し出すための押出部材とが各々独立していることで、眼内レンズの押出動作と液体の供給動作とを区別して行うことができるようになり、術者は手術の状況に応じて適切な状態で眼内レンズを眼内に注入させることができるようになる。   As described above, the push-out member for pushing out the intraocular lens and the push-out member for pushing out the liquid are independent from each other, so that the push-out operation of the intraocular lens and the liquid supply operation can be distinguished from each other. Thus, the surgeon can inject the intraocular lens into the eye in an appropriate state depending on the situation of the operation.

また、眼内レンズ挿入器具は上記の構成に限られるものではない。なお、以降の説明において上記の眼内レンズ挿入器具100と同じ構成には同じ図番号を用いて説明する。例えば、図5の第2実施形態の眼内レンズ挿入器具100aに示すように、貯留部120bの側面(筒部本体120)に灌流液pfを排出させる開口部pを設けても良い。このようにすると、押出部材130と押出部材140とが一体で押されるときに、開口部pから不必要な液体pfを排出することができる。眼内に液体を供給する必要があるときには開口部pを指等にて塞いだ状態で押出部材140を押し進めればよい。このようにすると、術者は眼内レンズ10を押出すタイミングで、状態に応じて液体pfの供給の有無を切り替えることができるようになる。また、この場合には、不要な液体pfを眼内に供給することを避けることができる。   The intraocular lens insertion device is not limited to the above configuration. In the following description, the same components as those in the intraocular lens insertion device 100 will be described using the same figure numbers. For example, as shown in the intraocular lens insertion device 100a of the second embodiment in FIG. 5, an opening p for discharging the perfusate pf may be provided on the side surface (tubular body 120) of the reservoir 120b. If it does in this way, when extrusion member 130 and extrusion member 140 are pushed together, unnecessary liquid pf can be discharged from opening p. When it is necessary to supply liquid into the eye, the pushing member 140 may be pushed forward while the opening p is closed with a finger or the like. If it does in this way, an operator will be able to switch the presence or absence of supply of the liquid pf according to a state at the timing which pushes out the intraocular lens 10. FIG. In this case, it is possible to avoid supplying unnecessary liquid pf into the eye.

また、図6の第3実施形態の眼内レンズ挿入器具100bに示すように、押出部材130の押圧部131aと押出部材140の押圧部141とは途中から一体で押されずに、完全に分けられていてもよい。このようにすると、術者は眼内レンズ10の押出動作と液体pfとの供給動作とを最後まで分けて行うことができる。   Further, as shown in the intraocular lens insertion device 100b of the third embodiment in FIG. 6, the pressing portion 131a of the pushing member 130 and the pushing portion 141 of the pushing member 140 are not pushed together and are completely separated from each other. It may be. In this way, the surgeon can perform the push-out operation of the intraocular lens 10 and the supply operation of the liquid pf separately to the end.

また、図7に示す第4実施形態の眼内レンズ挿入器具100cに示すように、眼内レンズ10を押し出すための押出部材(プランジャー)が通る空間120cを貯留部として用いることもできる。このときの押出部材150は、眼内レンズ10を押し出すための押出部材150aと、液体pfを押し出すための押出部材150bとが同軸にて別々に移動可能なように構成される。具体的には、押出部材150bはその外径が筒部本体120の内壁面に沿う形状に形成されると共に軸方向に貫通孔が形成されている。一方、押出部材150aは押出部材150bに形成された貫通孔内で挿通可能に設けられる。また、押出部材150aの押圧部151aは押出部材150bの押圧部151bよりも基端側となるように形成される。このような構成により、押圧部151bが押されることで液体pfのみが押し出され、押圧部151aが押されることで眼内レンズ10のみを押出すことができるようになる。   Moreover, as shown in the intraocular lens insertion device 100c of 4th Embodiment shown in FIG. 7, the space 120c through which the extrusion member (plunger) for pushing out the intraocular lens 10 passes can also be used as a storage part. The pushing member 150 at this time is configured such that the pushing member 150a for pushing out the intraocular lens 10 and the pushing member 150b for pushing out the liquid pf can be separately moved coaxially. Specifically, the extrusion member 150b has an outer diameter formed in a shape along the inner wall surface of the cylindrical body 120, and has a through hole in the axial direction. On the other hand, the pushing member 150a is provided so as to be able to be inserted through a through hole formed in the pushing member 150b. Further, the pressing portion 151a of the pushing member 150a is formed to be closer to the base end side than the pressing portion 151b of the pushing member 150b. With such a configuration, only the liquid pf is pushed out by pressing the pressing portion 151b, and only the intraocular lens 10 can be pushed out by pressing the pressing portion 151a.

眼内レンズの構成の説明図である。It is explanatory drawing of a structure of an intraocular lens. 眼内レンズ挿入器具の概略外観図である。It is a schematic external view of an intraocular lens insertion instrument. 眼内レンズ挿入器具の内部構成の模式図である。It is a schematic diagram of the internal structure of the intraocular lens insertion instrument. 眼内レンズ挿入器具の押出動作を説明する模式的断面図である。It is a typical sectional view explaining extrusion operation of an intraocular lens insertion instrument. 第2実施形態の眼内レンズ挿入器具の模式的断面図である。It is a typical sectional view of the intraocular lens insertion instrument of a 2nd embodiment. 第3実施形態の眼内レンズ挿入器具の模式的断面図である。It is a typical sectional view of the intraocular lens insertion instrument of a 3rd embodiment. 第4実施形態の眼内レンズ挿入器具の模式的断面図である。It is a typical sectional view of the intraocular lens insertion instrument of a 4th embodiment.

p 開口部
10 眼内レンズ
100 眼内レンズ挿入器具
110 挿入部
120 筒部本体
122 供給口
120b、120c 貯留部
130、140、150 押出部材
p opening part 10 intraocular lens 100 intraocular lens insertion instrument 110 insertion part 120 cylindrical part main body 122 supply port 120b, 120c storage part 130,140,150 push member

Claims (4)

変形可能な眼内レンズを眼内に挿入するために眼球に設けられた切開創に挿入する挿入部と、該挿入部を先端に持つ筒部本体と、眼内レンズを押し出すために前記筒部本体内部に前後方向に移動可能に設けられるプランジャーとを有する眼内レンズ挿入器具において、
前記筒部本体には、液体を貯留するための貯留部であって,前記挿入部に向けて前記液体を通すための通路が形成される貯留部と、該貯留部に外部から前記液体を供給するための供給口と、前記貯留部内の液体を前記挿入部に向けて押し出すための押出手段であって,前記プランジャーの押し出しとは別に独立して前記筒部本体に設けられる押出手段と、が設けられていることを特徴とする眼内レンズ挿入器具。
An insertion portion for inserting a deformable intraocular lens into an incision provided in the eyeball for inserting the intraocular lens into the eye, a cylindrical portion body having the insertion portion at a distal end, and the cylindrical portion for pushing out the intraocular lens In an intraocular lens insertion device having a plunger provided movably in the front-rear direction inside the main body,
The cylinder main body is a reservoir for storing liquid, a reservoir formed with a passage for passing the liquid toward the insertion portion, and the liquid is supplied from the outside to the reservoir A supply port for performing, and an extruding unit for extruding the liquid in the storage unit toward the insertion unit, the extruding unit being provided in the cylinder main body independently of the extruding of the plunger, An intraocular lens insertion device characterized by that.
請求項1の眼内レンズ挿入器具において、前記貯留部は前記プランジャーが挿通する前記筒部本体内領域とは区分けされた異なる領域に設けられていることを特徴とする眼内レンズ挿入器具。 2. The intraocular lens insertion device according to claim 1, wherein the storage portion is provided in a different region that is separated from the region in the cylinder main body through which the plunger is inserted. 請求項2の眼内レンズ挿入器具は、さらに前記貯留部内の液体を外部に排出するための排出口が前記貯留部から前記挿入部先端に至るまでの間に設けられていることを特徴とする眼内レンズ挿入器具。 The intraocular lens insertion device according to claim 2 is characterized in that a discharge port for discharging the liquid in the storage part to the outside is provided between the storage part and the distal end of the insertion part. Intraocular lens insertion device. 請求項1〜3の眼内レンズ挿入器具において、前記挿入部の内壁には水溶性の潤滑剤がコーティングされていることを特徴とする眼内レンズ挿入器具。 The intraocular lens insertion device according to claim 1, wherein the inner wall of the insertion portion is coated with a water-soluble lubricant.
JP2010071193A 2010-03-26 2010-03-26 Intraocular lens insertion device Active JP5570265B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2010071193A JP5570265B2 (en) 2010-03-26 2010-03-26 Intraocular lens insertion device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2010071193A JP5570265B2 (en) 2010-03-26 2010-03-26 Intraocular lens insertion device

Publications (3)

Publication Number Publication Date
JP2011200469A true JP2011200469A (en) 2011-10-13
JP2011200469A5 JP2011200469A5 (en) 2013-05-09
JP5570265B2 JP5570265B2 (en) 2014-08-13

Family

ID=44877873

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010071193A Active JP5570265B2 (en) 2010-03-26 2010-03-26 Intraocular lens insertion device

Country Status (1)

Country Link
JP (1) JP5570265B2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019518551A (en) * 2016-06-24 2019-07-04 ノバルティス アーゲー Intraocular lens delivery device with telescopic plunger
KR20200129801A (en) * 2019-05-10 2020-11-18 정영택 Intraocular lens insertion device for ophthalmic surgery supplied with perfusion fluid
WO2021154203A1 (en) * 2020-01-27 2021-08-05 Carl Zeiss Meditec Ag Injector assembly for inserting an intraocular lens

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007330783A (en) * 2006-05-18 2007-12-27 Canon Star Kk Insertion device for intraocular lens
JP2008307394A (en) * 2005-12-20 2008-12-25 Staar Japan Kk Insertion instrument for lens for intraocular insertion, and lens-built in type insertion instrument for intraocular insertion
JP2010057767A (en) * 2008-09-04 2010-03-18 Hoya Corp Intraocular lens insertion tool
JP2010063777A (en) * 2008-09-12 2010-03-25 Staar Japan Kk Insertion instrument for intraocular lens and insertion instrument with built-in type intraocular lens

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008307394A (en) * 2005-12-20 2008-12-25 Staar Japan Kk Insertion instrument for lens for intraocular insertion, and lens-built in type insertion instrument for intraocular insertion
JP2007330783A (en) * 2006-05-18 2007-12-27 Canon Star Kk Insertion device for intraocular lens
JP2010057767A (en) * 2008-09-04 2010-03-18 Hoya Corp Intraocular lens insertion tool
JP2010063777A (en) * 2008-09-12 2010-03-25 Staar Japan Kk Insertion instrument for intraocular lens and insertion instrument with built-in type intraocular lens

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019518551A (en) * 2016-06-24 2019-07-04 ノバルティス アーゲー Intraocular lens delivery device with telescopic plunger
KR20200129801A (en) * 2019-05-10 2020-11-18 정영택 Intraocular lens insertion device for ophthalmic surgery supplied with perfusion fluid
KR102391641B1 (en) 2019-05-10 2022-04-29 정영택 Intraocular lens insertion device for ophthalmic surgery supplied with perfusion fluid
WO2021154203A1 (en) * 2020-01-27 2021-08-05 Carl Zeiss Meditec Ag Injector assembly for inserting an intraocular lens
CN115052558A (en) * 2020-01-27 2022-09-13 卡尔蔡司医疗技术股份公司 Injector assembly for inserting intraocular lenses
CN115052558B (en) * 2020-01-27 2023-08-08 卡尔蔡司医疗技术股份公司 Injector assembly for insertion of intraocular lenses

Also Published As

Publication number Publication date
JP5570265B2 (en) 2014-08-13

Similar Documents

Publication Publication Date Title
JP4685897B2 (en) Lumen tip for lens injector for Woon Assisted delivery
KR100964765B1 (en) Lens delivery system cartridge and method of manufacture
EP2062552B1 (en) Lens delivery system with independently movable sliding block
US4919130A (en) Tool for inserting compressible intraocular lenses into the eye and method
JP5501658B2 (en) Intraocular lens insertion device
EP2343029B1 (en) Intraocular lens injection instrument
MX2008002091A (en) Lens delivery system.
JP5627861B2 (en) Intraocular lens insertion device
JP2012050713A (en) Intraocular lens injection instrument
JP5388094B2 (en) Intraocular insertion lens insertion device and intraocular insertion lens insertion device
JP5570265B2 (en) Intraocular lens insertion device
JP5752901B2 (en) Intraocular lens insertion device
US20070265636A1 (en) Lens delivery system
JP6427896B2 (en) Intraocular lens insertion device and intraocular lens insertion system
JP5255312B2 (en) Intraocular lens insertion device
JP6822628B2 (en) Intraocular lens insertion system, intraocular lens insertion device and tube
JP6777132B2 (en) Intraocular lens insertion device and intraocular lens insertion system
JP2016106655A (en) Intraocular lens insertion instrument
JP5469487B2 (en) Intraocular lens insertion device
JP2011182999A (en) Intraocular lens injection instrument
JP2023127789A (en) Intraocular lens insertion instrument
JP5269488B2 (en) Intraocular lens insertion device

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130322

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20130322

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20140130

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140204

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140407

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20140527

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140624

R150 Certificate of patent or registration of utility model

Ref document number: 5570265

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250