JP2009523196A - 紡糸ナノファイバー、医療用具および方法 - Google Patents
紡糸ナノファイバー、医療用具および方法 Download PDFInfo
- Publication number
- JP2009523196A JP2009523196A JP2008547479A JP2008547479A JP2009523196A JP 2009523196 A JP2009523196 A JP 2009523196A JP 2008547479 A JP2008547479 A JP 2008547479A JP 2008547479 A JP2008547479 A JP 2008547479A JP 2009523196 A JP2009523196 A JP 2009523196A
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- nanofibers
- nanofiber
- group
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
- D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
- D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L29/126—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/082—Inorganic materials
- A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L31/128—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing other specific inorganic fillers not covered by A61L31/126 or A61L31/127
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B37/00—Manufacture or treatment of flakes, fibres, or filaments from softened glass, minerals, or slags
- C03B37/01—Manufacture of glass fibres or filaments
- C03B37/011—Manufacture of glass fibres or filaments starting from a liquid phase reaction process, e.g. through a gel phase
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
- D01D5/00—Formation of filaments, threads, or the like
- D01D5/0007—Electro-spinning
- D01D5/0015—Electro-spinning characterised by the initial state of the material
- D01D5/003—Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F9/00—Artificial filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H3/00—Non-woven fabrics formed wholly or mainly of yarns or like filamentary material of substantial length
- D04H3/02—Non-woven fabrics formed wholly or mainly of yarns or like filamentary material of substantial length characterised by the method of forming fleeces or layers, e.g. reorientation of yarns or filaments
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
- D04H3/00—Non-woven fabrics formed wholly or mainly of yarns or like filamentary material of substantial length
- D04H3/08—Non-woven fabrics formed wholly or mainly of yarns or like filamentary material of substantial length characterised by the method of strengthening or consolidating
- D04H3/16—Non-woven fabrics formed wholly or mainly of yarns or like filamentary material of substantial length characterised by the method of strengthening or consolidating with bonds between thermoplastic filaments produced in association with filament formation, e.g. immediately following extrusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/249921—Web or sheet containing structurally defined element or component
- Y10T428/249924—Noninterengaged fiber-containing paper-free web or sheet which is not of specified porosity
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/249921—Web or sheet containing structurally defined element or component
- Y10T428/249924—Noninterengaged fiber-containing paper-free web or sheet which is not of specified porosity
- Y10T428/24994—Fiber embedded in or on the surface of a polymeric matrix
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/249921—Web or sheet containing structurally defined element or component
- Y10T428/249924—Noninterengaged fiber-containing paper-free web or sheet which is not of specified porosity
- Y10T428/24994—Fiber embedded in or on the surface of a polymeric matrix
- Y10T428/249941—Fiber is on the surface of a polymeric matrix having no embedded portion
Abstract
Description
ナノテクノロジーは、科学の法則およびエンジニアリングを用いてナノメートルスケールの寸法の材料または構造体を製造する新興分野である。ナノスケールの材料は、マクロ材料と比べて独特および特異な特性プロファイルを示すことができる。これらの材料が示す物理的、化学的および生物学的な特性,例えば特異な形状、配向性、表面化学、トポロジーおよび反応性は、これらの小さい寸法に由来する。これらの材料特性は、これらの材料についての独特の電気的、光学的、磁性的、機械的、熱的および生物学的な特性という結果をもたらすことができる。
本開示は、ナノファイバーを生成できる化合物、該化合物から生成されて得られるナノファイバー、ならびに該ナノファイバーおよびポリマーを用いて作製されるナノファイバー補強されたポリマーを提供する。ナノファイバーの形成において用いる化合物は、ナノファイバー補強されたポリマーを形成するためにポリマーの一部との非共有結合を形成可能な化学結合部分を含む。この相互作用は、このような非共有結合相互作用がない場合にナノファイバーで生じうる集塊または凝集なしで、ナノファイバーがポリマーと一体化することを可能にする。電界紡糸されたナノファイバーは、これらの小さい直径により、より大きい表面−対−体積比を有し、これにより、より大きい直径の繊維と比べてこれらがポリマーとのより多量の非共有結合を受けることが可能になる。
[(R2O)3-Si-R3]z-Y-[(R1)m-Ox]q-Y'-[R3-Si-(OR2)3]z
のものであり、式中、各R1,R2およびR3は同一のまたは異なる(すなわち独立である)有機基であることができる。このような有機基の例としては、直鎖または分岐のアルキル基、直鎖または分岐のアルキレン基(ここで、各R1、R2およびR3は任意に、有機基の主鎖中またはそれによる側鎖中に、官能基中等で存在できるヘテロ原子を含む)が挙げられる。xおよびzは各々独立に0または1;mは1から18;qは1から200である。YおよびY’は、ポリマーの一部と非共有結合を形成できる化学結合部分であり、ここでYおよびY’はともに:
Yについて-NH-(C=O)-O- およびY’について-(C=O)-NH- 但しz=1;
Yについて-NH-(C=O)- およびY’について-(C=O)-NH- 但しx=0 かつz=1;
Yについて-0-(C=O)- およびY’について-(C=O)- 但しz=1;
YおよびY’について-(NR4)-(C=O)-(NH)- 但しz=1;ならびに
YおよびY’について-N-[CH2-(CHOH)-CH2-O-R3-Si-(OR2)3]2 但しz=0;
からなる群から選択される。
Claims (28)
- ナノファイバーを作製する方法であって:
式(式I):
[(R2O)3-Si-R3]z-Y-[(R1)m-Ox]q-Y'-[R3-Si-(OR2)3]z
式中、xおよびzは各々独立に0または1;mは1から18;qは1から200;R1,R2およびR3は各々独立に有機基;そしてYおよびY’はともに、
Yについて-NH-(C=O)-O- およびY’について-(C=O)-NH- 但しz=1;
Yについて-NH-(C=O)- およびY’について-(C=O)-NH- 但しx=0 かつz=1;
Yについて-0-(C=O)- およびY’について-(C=O)- 但しz=1;
YおよびY’について-(NR4)-(C=O)-(NH)- 但しz=1,およびR4は有機基またはH;ならびに
YおよびY’について-N-[CH2-(CHOH)-CH2-O-R3-Si-(OR2)3]2 但しz=0;
からなる群から選択される:
の少なくとも1種の化合物を用意すること;
ゾル−ゲルプロセスを用いて、式Iの少なくとも1種の化合物から架橋ネットワークを形成すること;ならびに
該式Iの少なくとも1種の化合物からの該架橋ネットワークの溶液からナノファイバーを紡糸すること
を含む、方法。 - ナノファイバーを紡糸することが、式Iの少なくとも1種の化合物からの架橋ネットワークの溶液からナノファイバーを電界紡糸することを含む、請求項1に記載の方法。
- ナノファイバーを紡糸することが、式Iの少なくとも1種の化合物からの架橋ネットワークの溶液からナノファイバーを乾式紡糸することを含む、請求項1に記載の方法。
- ナノファイバーを紡糸することが、Y基と非共有結合することが可能な官能基を有するポリマー上にナノファイバーを集合させて生体材料を形成することを含む、請求項1〜3のいずれかに記載の方法。
- ナノファイバーを紡糸することが、医療用具を成形するために使用する型の表面上にナノファイバーを集合させることを含む、請求項1〜3のいずれかに記載の方法。
- 型の表面上に集合させたナノファイバーの周囲に少なくとも部分的にポリマーを射出成形することを含み、該ポリマーが、Y基との非共有結合を形成することが可能な化学的部分を含む、請求項5に記載の方法。
- 各R1およびR3が独立に(C1−C18)アルキレン基であり、かつR2が(C1−C18)アルキル基である、請求項1〜6のいずれかに記載の方法。
- 紡糸プロセスによって生成された、式(式I):
[(R2O)3-Si-R3]z-Y-[(R1)m-Ox]q-Y'-[R3-Si-(OR2)3]z
式中、xおよびzは各々独立に0または1;mは1から18;qは1から200;R1,R2およびR3は各々独立に有機基;そしてYおよびY’はともに、
Yについて-NH-(C=O)-O- およびY’について-(C=O)-NH- 但しz=1;
Yについて-NH-(C=O)- およびY’について-(C=O)-NH- 但しx=0 かつz=1;
Yについて-0-(C=O)- およびY’について-(C=O)- 但しz=1;
YおよびY’について-(NR4)-(C=O)-(NH)- 但しz=1,およびR4は有機基またはH;ならびに
YおよびY’について-N-[CH2-(CHOH)-CH2-O-R3-Si-(OR2)3]2 但しz=0;
からなる群から選択される:
の化合物から形成されたナノファイバー。 - ナノファイバーを生成するために用いる紡糸プロセスが乾式紡糸プロセスである、請求項8に記載のナノファイバー。
- ナノファイバーを生成するために用いる紡糸プロセスが電界紡糸プロセスである、請求項8に記載のナノファイバー。
- 補強成分としてポリマーとともに用いて生体材料を形成する、請求項8〜10のいずれかに記載のナノファイバー。
- ポリマーをコートして生体材料を形成する、請求項11に記載のナノファイバー。
- ポリマー中に埋め込んで生体材料を形成する、請求項11〜12のいずれかに記載のナノファイバー。
- ポリマーの一部と非共有結合することが可能な化学的部分を含む、請求項11〜13のいずれかに記載のナノファイバー。
- 式Iの化合物がゾル−ゲルプロセスを用いて架橋ネットワークを形成できる、請求項8〜14のいずれかに記載のナノファイバー。
- 請求項8〜15のいずれかに記載のナノファイバーから作製された医療用具。
- 各R1およびR3が独立に(C1−C18)アルキレン基であり、かつR2が(C1−C18)アルキル基である、請求項8〜16のいずれかに記載のナノファイバー。
- ナノファイバー補強されたポリマーであって:
ポリマー;ならびに
ゾル−ゲルプロセスを経て形成された金属酸化物系ポリマーの架橋ネットワークのナノファイバーであって、金属酸化物系ポリマーが、ポリマーの一部と非共有結合を形成することが可能な化学的部分を含むもの;
を含む、ポリマー。 - ナノファイバーがポリマーの少なくとも一部の表面をコートする、請求項18に記載の補強されたポリマー。
- ナノファイバーがポリマーの少なくとも一部の表面上のランダムパターンで存在する、請求項19に記載の補強されたポリマー。
- ナノファイバーがポリマーの少なくとも一部の中に埋め込まれている、請求項18〜20のいずれかに記載の補強されたポリマー。
- ナノファイバーが、ポリマーの少なくとも一部の中に埋め込まれたランダムパターンで存在する、請求項21に記載の補強されたポリマー。
- 架橋ネットワークの金属酸化物系ポリマーが、式(式I):
[(R2O)3-Si-R3]z-Y-[(R1)m-Ox]q-Y'-[R3-Si-(OR2)3]z
式中、xおよびzは各々独立に0または1;mは1から18;qは1から200;R1,R2およびR3は各々独立に有機基;そしてYおよびY’はともに、
Yについて-NH-(C=O)-O- およびY’について-(C=O)-NH- 但しz=1;
Yについて-NH-(C=O)- およびY’について-(C=O)-NH- 但しx=0 かつz=1;
Yについて-0-(C=O)- およびY’について-(C=O)- 但しz=1;
YおよびY’について-(NR4)-(C=O)-(NH)- 但しz=1,およびR4は有機基またはH;ならびに
YおよびY’について-N-[CH2-(CHOH)-CH2-O-R3-Si-(OR2)3]2 但しz=0;
からなる群から選択され、
Yは、ポリマーの一部と非共有結合できる化学的部分である:
の少なくとも1種の化合物を用いてゾル−ゲルプロセスにおいて形成されている、請求項18〜22のいずれかに記載の補強されたポリマー。 - 各R1およびR3が独立に(C1−C18)アルキレン基であり、かつR2が(C1−C18)アルキル基である、請求項23に記載の補強されたポリマー。
- 金属酸化物系ポリマーの化学的部分と化学的に結合できるポリマーの一部が、ウレタン、エステル、アミド、イミド、尿素およびこれらの組合せの群から選択される、請求項18〜24のいずれかに記載の補強されたポリマー。
- ポリマーが、ポリアミド、ポリウレタン、ポリウレア、ポリウレタン−ウレア、およびポリエステルの群から選択される、請求項18〜25のいずれかに記載の補強されたポリマー。
- 請求項18〜26のいずれかに記載の補強されたポリマーを含む、生体材料。
- 請求項18〜27のいずれかに記載の補強されたポリマーを含む、医療用具。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/318,027 | 2005-12-23 | ||
US11/318,027 US8455088B2 (en) | 2005-12-23 | 2005-12-23 | Spun nanofiber, medical devices, and methods |
PCT/US2006/048576 WO2007117296A2 (en) | 2005-12-23 | 2006-12-20 | Spun nanofiber, medical devices, and methods |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2009523196A true JP2009523196A (ja) | 2009-06-18 |
JP2009523196A5 JP2009523196A5 (ja) | 2010-02-12 |
JP4855481B2 JP4855481B2 (ja) | 2012-01-18 |
Family
ID=38191990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008547479A Expired - Fee Related JP4855481B2 (ja) | 2005-12-23 | 2006-12-20 | 紡糸ナノファイバー、医療用具および方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US8455088B2 (ja) |
EP (1) | EP1963553B1 (ja) |
JP (1) | JP4855481B2 (ja) |
CA (1) | CA2634415A1 (ja) |
WO (1) | WO2007117296A2 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010519431A (ja) * | 2007-02-27 | 2010-06-03 | ピーピージー・インダストリーズ・オハイオ・インコーポレイテッド | 有機−無機電界紡糸繊維 |
JP2011178870A (ja) * | 2010-03-01 | 2011-09-15 | Kri Inc | 繊維補強複合材料、その製造方法、複合材料成形体および複合材料成形体の積層体 |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7854756B2 (en) * | 2004-01-22 | 2010-12-21 | Boston Scientific Scimed, Inc. | Medical devices |
WO2005123995A1 (en) * | 2004-06-17 | 2005-12-29 | Korea Research Institute Of Chemical Technology | Filament bundle type nano fiber and manufacturing method thereof |
CA2628012C (en) * | 2005-10-17 | 2015-02-03 | The University Of Akron | Hybrid manufacturing platform to produce multifunctional polymeric films |
US20080145655A1 (en) * | 2006-12-14 | 2008-06-19 | Ppg Industries Ohio, Inc. | Electrospinning Process |
US7632563B2 (en) * | 2006-12-14 | 2009-12-15 | Ppg Industries Ohio, Inc. | Transparent composite articles |
EP2157937B1 (en) | 2007-06-04 | 2017-03-22 | Sequent Medical, Inc. | Devices for treatment of vascular defects |
KR101691670B1 (ko) * | 2007-11-09 | 2016-12-30 | 커민즈 필트레이션 아이피, 인크. | 열 안정화된 백 하우스 필터 및 매체 |
US20100249257A1 (en) * | 2007-11-27 | 2010-09-30 | University Of Akron | Crystalline polyolefin blend comprising polyhedral oligomeric silsesquioxane nanoparticles |
EP2276336A4 (en) * | 2008-04-25 | 2012-04-18 | Univ Akron | METHOD BASED ON FILM CUTTING AND FOR MANUFACTURING FUNCTIONAL FILM ENHANCED BY NANOFIBERS |
CN106974691A (zh) | 2008-05-02 | 2017-07-25 | 斯昆特医疗公司 | 用于治疗血管缺损的丝状装置 |
US8389083B2 (en) * | 2008-10-17 | 2013-03-05 | Boston Scientific Scimed, Inc. | Polymer coatings with catalyst for medical devices |
JP2012533657A (ja) * | 2009-07-15 | 2012-12-27 | ザ ユニバーシティ オブ アクロン | 多機能性導電性/透明/可撓性膜の製造 |
US20110152993A1 (en) | 2009-11-05 | 2011-06-23 | Sequent Medical Inc. | Multiple layer filamentary devices or treatment of vascular defects |
US9056006B2 (en) | 2012-07-02 | 2015-06-16 | Boston Scientific Scimed, Inc. | Prosthetic heart valve formation |
CN103570028A (zh) * | 2012-07-23 | 2014-02-12 | 深圳富泰宏精密工业有限公司 | 二氧化硅溶胶,应用该二氧化硅溶胶对金属基体进行表面处理的方法及制品 |
CN103848428A (zh) * | 2012-12-07 | 2014-06-11 | 深圳富泰宏精密工业有限公司 | 二氧化硅溶胶,应用该二氧化硅溶胶对金属基体进行表面处理的方法及其制品 |
CN103865379A (zh) * | 2012-12-11 | 2014-06-18 | 深圳富泰宏精密工业有限公司 | 聚二甲基硅氧烷溶胶,应用该聚二甲基硅氧烷溶胶对金属基体进行表面处理的方法及制品 |
US9078658B2 (en) | 2013-08-16 | 2015-07-14 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
US9955976B2 (en) | 2013-08-16 | 2018-05-01 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
US20150064458A1 (en) * | 2013-08-28 | 2015-03-05 | Eaton Corporation | Functionalizing injection molded parts using nanofibers |
WO2015084951A1 (en) * | 2013-12-04 | 2015-06-11 | Cornell University | Ceramic-polymer hybrid nanostructures, methods for producing and applications thereof |
US9629635B2 (en) | 2014-04-14 | 2017-04-25 | Sequent Medical, Inc. | Devices for therapeutic vascular procedures |
US10314696B2 (en) | 2015-04-09 | 2019-06-11 | Boston Scientific Scimed, Inc. | Prosthetic heart valves having fiber reinforced leaflets |
US10426609B2 (en) | 2015-04-09 | 2019-10-01 | Boston Scientific Scimed, Inc. | Fiber reinforced prosthetic heart valve having undulating fibers |
US10299915B2 (en) | 2015-04-09 | 2019-05-28 | Boston Scientific Scimed, Inc. | Synthetic heart valves composed of zwitterionic polymers |
US10716671B2 (en) | 2015-07-02 | 2020-07-21 | Boston Scientific Scimed, Inc. | Prosthetic heart valve composed of composite fibers |
US10413403B2 (en) | 2015-07-14 | 2019-09-17 | Boston Scientific Scimed, Inc. | Prosthetic heart valve including self-reinforced composite leaflets |
US10195023B2 (en) | 2015-09-15 | 2019-02-05 | Boston Scientific Scimed, Inc. | Prosthetic heart valves including pre-stressed fibers |
EP3400132A4 (en) * | 2016-01-08 | 2019-08-07 | Clarcor Inc. | USE OF MICROFIBRES AND / OR NANOFIBRES IN CLOTHES AND SHOES |
WO2017200920A1 (en) | 2016-05-19 | 2017-11-23 | Boston Scientific Scimed, Inc. | Prosthetic valves, valve leaflets and related methods |
ES2584405A1 (es) * | 2016-06-08 | 2016-09-27 | Universitat Politècnica De València | Compuesto no tejido bioelastómero |
EP3510188B1 (en) * | 2016-09-09 | 2023-07-12 | Forta, LLC | Enhancement of reinforcing fibers, their applications, and methods of making same |
JP6946464B2 (ja) | 2017-04-25 | 2021-10-06 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 生体適合性ポリイソブチレン−繊維複合材料及び方法 |
JP7469323B2 (ja) | 2019-03-15 | 2024-04-16 | マイクロベンション インコーポレイテッド | 血管障害の治療のためのフィラメント状デバイス |
US11317921B2 (en) | 2019-03-15 | 2022-05-03 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
US11291453B2 (en) | 2019-03-15 | 2022-04-05 | Sequent Medical, Inc. | Filamentary devices having a flexible joint for treatment of vascular defects |
Family Cites Families (193)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US674970A (en) * | 1900-09-14 | 1901-05-28 | Michael A Kennedy | Exhibiting device. |
US2928858A (en) * | 1956-10-12 | 1960-03-15 | Union Carbide Corp | Organosilicon acylamino compounds and process for producing the same |
GB1527592A (en) | 1974-08-05 | 1978-10-04 | Ici Ltd | Wound dressing |
US4780337A (en) | 1986-12-29 | 1988-10-25 | Massachusetts Institute Of Technology | Hybrid polymers derived from Si-H containing organosilicon polymers and unsaturated metal alkoxides |
EP0297176B1 (en) | 1987-07-03 | 1992-08-05 | Asahi Glass Company Ltd. | Process for producing silica glass fibers |
US5180757A (en) * | 1987-12-16 | 1993-01-19 | Michael Lucey | Photopolymerizable compositions used in electronics |
US5316695A (en) * | 1989-08-10 | 1994-05-31 | Virginia Tech Intellectual Properties, Inc. | Use of polymeric catalyst in synthesis of sol-gel derived ceramic materials |
US5593852A (en) | 1993-12-02 | 1997-01-14 | Heller; Adam | Subcutaneous glucose electrode |
US5254744A (en) | 1992-02-28 | 1993-10-19 | E. I. Du Pont De Nemours And Company | Preparation and purification of poly(tetramethylene ether) formal glycols and poly(oxybutylene formal) glycols |
US6696585B1 (en) * | 1993-04-13 | 2004-02-24 | Southwest Research Institute | Functionalized nanoparticles |
US6258974B1 (en) | 1993-04-13 | 2001-07-10 | Southwest Research Institute | Metal oxide compositions composites thereof and method |
US5389170A (en) * | 1993-06-11 | 1995-02-14 | Dow Corning Corporation | Method for bonding substrates using molten moisture reactive organosiloxane compositions |
US20020197456A1 (en) | 1993-06-30 | 2002-12-26 | Pope Edward J. A. | Integrated electro-luminescent biochip |
US6001522A (en) | 1993-07-15 | 1999-12-14 | Imation Corp. | Barrier layer for photoconductor elements comprising an organic polymer and silica |
JP3334719B2 (ja) | 1993-09-16 | 2002-10-15 | 倭 窪田 | 創傷被覆用材料および創傷被覆用組成物 |
US5716565A (en) * | 1993-09-27 | 1998-02-10 | Alfred University | Process for making ultra-fine stabilized zirconia particles |
US5616650A (en) * | 1993-11-05 | 1997-04-01 | Lanxide Technology Company, Lp | Metal-nitrogen polymer compositions comprising organic electrophiles |
US5817327A (en) * | 1994-07-27 | 1998-10-06 | The Trustees Of The University Of Pennsylvania | Incorporation of biologically active molecules into bioactive glasses |
DE4430669A1 (de) * | 1994-08-29 | 1996-03-07 | Hoechst Ag | Verfahren zur Herstellung von faserverstärkten Xerogelen, sowie ihre Verwendung |
US5486565A (en) * | 1994-12-02 | 1996-01-23 | Dow Corning Corporation | Organosilicon compounds and low temperature curing organosiloxane compositions containing same |
US6846493B2 (en) * | 1995-09-01 | 2005-01-25 | Millenium Biologix Inc. | Synthetic biomaterial compound of calcium phosphate phases particularly adapted for supporting bone cell activity |
BR9610357B1 (pt) * | 1995-09-01 | 2011-05-03 | composição sinterizada artificial bioativa, estrutura microporosa cerámica aparente, dispositivo implantável, processo para o cultivo de células de ossos funcionais e kit para monitorar e quantificar a atividade das referidas células | |
US5681872A (en) | 1995-12-07 | 1997-10-28 | Orthovita, Inc. | Bioactive load bearing bone graft compositions |
WO1997035000A1 (en) | 1996-03-18 | 1997-09-25 | The Trustees Of The University Of Pennsylvania | Bioactive material substrate for enhanced cellular attachment and function |
BR9710709A (pt) | 1996-05-15 | 1999-08-17 | Hyperion Catalysis Int | Estruturas de carbono porosas e rigidas processos de fabrica-Æo processos de uso e produtos que as cont-m |
CN1219872A (zh) | 1996-05-24 | 1999-06-16 | 血管技术药物公司 | 治疗或预防身体通道疾病的组合物和方法 |
US6039897A (en) * | 1996-08-28 | 2000-03-21 | University Of Washington | Multiple patterned structures on a single substrate fabricated by elastomeric micro-molding techniques |
US5665823A (en) | 1996-08-30 | 1997-09-09 | Dow Corning Corporation | Polyisobutylene polymers having acrylic functionality |
US7507483B2 (en) * | 1997-02-04 | 2009-03-24 | Jeffrey Schwartz | Enhanced bonding layers on native oxide surfaces |
US6645644B1 (en) | 1996-10-17 | 2003-11-11 | The Trustees Of Princeton University | Enhanced bonding of phosphoric and phosphoric acids to oxidized substrates |
US7569285B2 (en) * | 1996-10-17 | 2009-08-04 | The Trustees Of Princeton University | Enhanced bonding layers on titanium materials |
US6162530A (en) | 1996-11-18 | 2000-12-19 | University Of Connecticut | Nanostructured oxides and hydroxides and methods of synthesis therefor |
US5914356A (en) * | 1996-12-06 | 1999-06-22 | Orthovita, Inc. | Bioactive load bearing bone bonding compositions |
US6280838B1 (en) | 1997-01-10 | 2001-08-28 | U. S. Philips Corporation | Optical element, a display device provided with said optical element, and a method of manufacturing the optical element |
ES2184236T3 (es) * | 1997-02-06 | 2003-04-01 | Therasense Inc | Sensor in vitro de analitos de pequeño volumen. |
WO1998038251A1 (de) | 1997-02-25 | 1998-09-03 | Bayer Aktiengesellschaft | Organisch-anorganische hybridmaterialien |
US6548590B1 (en) * | 2000-03-22 | 2003-04-15 | Integument Technologies, Inc. | Polymer and inorganic-organic hybrid composites and methods for making and using same |
JP3602145B2 (ja) | 1997-06-03 | 2004-12-15 | イノジェネティックス・ナムローゼ・フェンノートシャップ | メタクリルアミド修飾ゼラチンから構成されるポリマーに基づく新たな医薬品 |
US6869938B1 (en) * | 1997-06-17 | 2005-03-22 | Fziomed, Inc. | Compositions of polyacids and polyethers and methods for their use in reducing adhesions |
US6448331B1 (en) | 1997-07-15 | 2002-09-10 | Asahi Kasei Kabushiki Kaisha | Alkoxysilane/organic polymer composition for thin insulating film production and use thereof |
US6599631B2 (en) | 2001-01-26 | 2003-07-29 | Nanogram Corporation | Polymer-inorganic particle composites |
US6060026A (en) * | 1997-07-31 | 2000-05-09 | Starfire Electronic Development & Mktg., Ltd. | Photoelectrochemical device containing a quantum confined silicon particle |
US6361660B1 (en) * | 1997-07-31 | 2002-03-26 | Avery N. Goldstein | Photoelectrochemical device containing a quantum confined group IV semiconductor nanoparticle |
US5854298A (en) | 1997-09-29 | 1998-12-29 | Lockheed Martin Corporation | Photocurable low observable aircraft materials |
EP0908494A3 (en) | 1997-10-08 | 1999-11-10 | E.I. Dupont De Nemours And Company | Uniformly coated particulate metal oxide |
FR2770153B1 (fr) | 1997-10-29 | 1999-11-19 | Commissariat Energie Atomique | Gels hybrides inorganiques-organiques pour l'extraction d'especes chimiques telles que les lanthanides et les actinides, et leur preparation |
EP1041261A4 (en) * | 1997-12-15 | 2003-07-16 | Hitachi Ltd | GAS TURBINE USED FOR GENERATING ENERGY AND MIXED SYSTEM FOR GENERATING ENERGY |
US6391999B1 (en) * | 1998-02-06 | 2002-05-21 | Rensselaer Polytechnic Institute | Epoxy alkoxy siloxane oligomers |
US6069259A (en) * | 1998-02-06 | 2000-05-30 | Rensselaer Polytechnic Institute | Multifunctional polymerizible alkoxy siloxane oligomers |
US6103033A (en) | 1998-03-04 | 2000-08-15 | Therasense, Inc. | Process for producing an electrochemical biosensor |
US6134461A (en) * | 1998-03-04 | 2000-10-17 | E. Heller & Company | Electrochemical analyte |
US6559631B1 (en) * | 1998-04-10 | 2003-05-06 | General Electric Company | Temperature compensation for an electronic electricity meter |
US6131580A (en) | 1998-04-17 | 2000-10-17 | The University Of Washington | Template imprinted materials by RFGD plasma deposition |
US6175752B1 (en) * | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
WO1999064504A1 (de) | 1998-06-05 | 1999-12-16 | Cabot Corporation | Nanoporöse interpenetrierende organisch-anorganische netzwerke |
US20050244954A1 (en) | 1998-06-23 | 2005-11-03 | Blackburn Gary F | Binding acceleration techniques for the detection of analytes |
US6210790B1 (en) * | 1998-07-15 | 2001-04-03 | Rensselaer Polytechnic Institute | Glass-like composites comprising a surface-modified colloidal silica and method of making thereof |
US6251260B1 (en) * | 1998-08-24 | 2001-06-26 | Therasense, Inc. | Potentiometric sensors for analytic determination |
US6531704B2 (en) * | 1998-09-14 | 2003-03-11 | Nanoproducts Corporation | Nanotechnology for engineering the performance of substances |
AU771319B2 (en) | 1998-09-28 | 2004-03-18 | Hyperion Catalysis International, Inc. | Fibril composite electrode for electrochemical capacitors |
WO2000022207A2 (en) * | 1998-10-01 | 2000-04-20 | The University Of Akron | Process and apparatus for the production of nanofibers |
US6591125B1 (en) | 2000-06-27 | 2003-07-08 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
US6338790B1 (en) * | 1998-10-08 | 2002-01-15 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
DE19855999A1 (de) | 1998-12-04 | 2000-06-15 | Bayer Ag | Alkoxysilanhaltige Lackzubereitung |
US6630231B2 (en) * | 1999-02-05 | 2003-10-07 | 3M Innovative Properties Company | Composite articles reinforced with highly oriented microfibers |
CA2359699C (en) * | 1999-02-22 | 2009-08-11 | Bioxid Oy | Biodegradable ceramic fibres from silica sols |
TWI291472B (en) | 1999-03-23 | 2007-12-21 | Univ Carnegie Mellon | Catalytic processes for the controlled polymerization of free radically (co)polymerizable monomers and functional polymeric systems prepared thereby |
US20030129654A1 (en) | 1999-04-15 | 2003-07-10 | Ilya Ravkin | Coded particles for multiplexed analysis of biological samples |
AU769571B2 (en) * | 1999-04-28 | 2004-01-29 | Universitat Zurich | Polyionic coatings in analytic and sensor devices |
JP4801301B2 (ja) | 1999-06-18 | 2011-10-26 | アボット ダイアベティス ケア インコーポレイテッド | 物質移動が制限された生体内分析物センサー |
US6214530B1 (en) * | 1999-06-30 | 2001-04-10 | Tulalip Consultoria Comercial Sociedade Unidessoal S.A. | Base film with a conductive layer and a magnetic layer |
US6368535B1 (en) | 1999-08-06 | 2002-04-09 | Dow Corning Corporation | Condensation reaction curable silsesquioxane resin composition and methods for the synthesis and cure thereof |
US6649083B1 (en) | 1999-08-12 | 2003-11-18 | Board Of Trustees Of Michigan State University | Combined porous organic and inorganic oxide materials prepared by non-ionic surfactant templating route |
US6479565B1 (en) | 1999-08-16 | 2002-11-12 | Harold R. Stanley | Bioactive ceramic cement |
US6753454B1 (en) * | 1999-10-08 | 2004-06-22 | The University Of Akron | Electrospun fibers and an apparatus therefor |
US6616819B1 (en) | 1999-11-04 | 2003-09-09 | Therasense, Inc. | Small volume in vitro analyte sensor and methods |
JP2001191025A (ja) * | 1999-11-04 | 2001-07-17 | Dainippon Printing Co Ltd | 高分子−微粒子複合体の製造方法 |
ES2225264T3 (es) | 1999-11-12 | 2005-03-16 | Clinical Micro Sensors, Inc. | Tecnicas de aceleracion de union para la deteccion de analitos. |
AU1848601A (en) | 1999-12-09 | 2001-06-18 | Bio Syntech Canada Inc | Mineral-polymer hybrid composition |
US7013179B2 (en) | 2000-01-07 | 2006-03-14 | Biowave Corporation | Percutaneous electrode array |
AU2001241466A1 (en) | 2000-02-10 | 2001-08-20 | The Government of the United States of America as represented by the Administrator of the National Aeronautics Space Administration (NASA) | Phenylethynyl-containing imide silanes |
KR20000063142A (ko) * | 2000-02-17 | 2000-11-06 | 이응찬 | 폴리오르가노실세스키옥산 제조용 출발물질,폴리오르가노실세스키옥산 및 폴리오르가노실세스키옥산제조방법 |
AUPQ573300A0 (en) * | 2000-02-21 | 2000-03-16 | Australian Nuclear Science & Technology Organisation | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use |
US6478994B1 (en) | 2000-03-30 | 2002-11-12 | Trustees Of The University Of Pennsylvania | Method for making boron carbide containing ceramics |
US6368565B1 (en) * | 2000-04-28 | 2002-04-09 | Dennis J. Michaelson | Sterilization apparatus for dental and orthodontic tools |
FR2811323B1 (fr) * | 2000-07-07 | 2006-10-06 | Fuma Tech Gmbh | Materiau hybride, utilisation dudit materiau hybride et procede de sa fabrication |
US6589457B1 (en) | 2000-07-31 | 2003-07-08 | The Regents Of The University Of California | Polymer-assisted aqueous deposition of metal oxide films |
DE10040897B4 (de) | 2000-08-18 | 2006-04-13 | TransMIT Gesellschaft für Technologietransfer mbH | Nanoskalige poröse Fasern aus polymeren Materialien |
DE60137943D1 (de) * | 2000-08-31 | 2009-04-23 | Jagotec Ag | Gemahlene partikel |
US6303290B1 (en) | 2000-09-13 | 2001-10-16 | The Trustees Of The University Of Pennsylvania | Encapsulation of biomaterials in porous glass-like matrices prepared via an aqueous colloidal sol-gel process |
US7008524B2 (en) * | 2000-10-03 | 2006-03-07 | Hrl Laboratories, Llc | Sensors with variable response behavior |
WO2002031135A1 (en) | 2000-10-12 | 2002-04-18 | Institute Of Materials Research And Engineering | Non-disruptive three-dimensional culture and harvest system for anchorage-dependent cells |
AU2002224399A1 (en) | 2000-10-17 | 2002-04-29 | Neophotonics Corporation | Coating formation by reactive deposition |
US6828404B2 (en) | 2000-10-20 | 2004-12-07 | Rensselaer Polytechnic Institute | Polymerizable siloxanes |
US6566456B1 (en) * | 2000-11-03 | 2003-05-20 | Chung-Shan Institute Of Science & Technology | Method of preparing a hybrid of polyvinylimidazole and silica |
DE10102739A1 (de) * | 2001-01-23 | 2002-07-25 | Bayer Ag | Verfahren zur Herstellung von Sol-Gel-Kondensaten auf Basis polyfunktioneller Organosilane sowie deren Verwendung |
US6555175B2 (en) * | 2001-02-20 | 2003-04-29 | Joseph E. Johnson | Process for the surface modification of a polymeric substrate |
US20020123592A1 (en) | 2001-03-02 | 2002-09-05 | Zenastra Photonics Inc. | Organic-inorganic hybrids surface adhesion promoter |
US6841601B2 (en) * | 2001-03-13 | 2005-01-11 | Dais-Analytic Corporation | Crosslinked polymer electrolyte membranes for heat and moisture exchange devices |
US7179860B2 (en) | 2001-03-13 | 2007-02-20 | Liwei Cao | Crosslinked polymer electrolyte membranes for heat, ion and moisture exchange devices |
FI20010523A0 (fi) | 2001-03-16 | 2001-03-16 | Yli Urpo Antti | Soolien, geelien ja niiden seosten käsittely |
US7265174B2 (en) | 2001-03-22 | 2007-09-04 | Clemson University | Halogen containing-polymer nanocomposite compositions, methods, and products employing such compositions |
WO2002096914A2 (en) | 2001-04-30 | 2002-12-05 | Crompton Corporation | Hybrid silicon-containing coupling agents for filled elastomer compositions |
US6713011B2 (en) * | 2001-05-16 | 2004-03-30 | The Research Foundation At State University Of New York | Apparatus and methods for electrospinning polymeric fibers and membranes |
US20040023253A1 (en) * | 2001-06-11 | 2004-02-05 | Sandeep Kunwar | Device structure for closely spaced electrodes |
US20020192289A1 (en) | 2001-06-18 | 2002-12-19 | Ji Zheng | Polymer gel for cancer treatment |
EP1401571B1 (en) * | 2001-06-22 | 2006-05-10 | Argonide Corporation | Sub-micron filter |
US6506921B1 (en) * | 2001-06-29 | 2003-01-14 | Virginia Tech Intellectual Properties, Inc. | Amine compounds and curable compositions derived therefrom |
US20040009598A1 (en) * | 2001-07-11 | 2004-01-15 | Hench Larry L | Use of bioactive glass compositions to stimulate osteoblast production |
KR20040017297A (ko) | 2001-07-13 | 2004-02-26 | 메비올 가부시키가이샤 | 조직·장기 재생용 재료 및 조직·장기 재생 방법 |
ATE307784T1 (de) | 2001-08-01 | 2005-11-15 | Novara Technology Srl | Sol-gel-verfahren für die herstellung von vorformen für optische fasern |
US6680016B2 (en) * | 2001-08-17 | 2004-01-20 | University Of Dayton | Method of forming conductive polymeric nanocomposite materials |
US6520425B1 (en) * | 2001-08-21 | 2003-02-18 | The University Of Akron | Process and apparatus for the production of nanofibers |
WO2003020226A2 (en) * | 2001-08-31 | 2003-03-13 | L'oreal S.A. | Cosmetic compositions comprising nanoparticles and processes for using the same |
US7020560B2 (en) * | 2001-09-06 | 2006-03-28 | University Of Tennessee Research Foundation | Methods for cell-based combinatorial logic |
CN1182190C (zh) | 2001-09-27 | 2004-12-29 | 中国科学院长春应用化学研究所 | 原位聚合制备聚烯烃/无机组份纳米复合材料的方法 |
US20030059742A1 (en) * | 2001-09-24 | 2003-03-27 | Webster Thomas J. | Osteointegration device and method |
US6812268B2 (en) | 2001-11-01 | 2004-11-02 | Science Applications International Corporation | Methods for material fabrication utilizing the polymerization of nanoparticles |
AU2002365162A1 (en) * | 2001-11-14 | 2003-07-09 | Northwestern University | Self-assembly and mineralization of peptide-amphiphile nanofibers |
US20050215718A1 (en) | 2002-01-04 | 2005-09-29 | Murali Rajagopalan | Nanocomposite ethylene copolymer compositions for golf balls |
WO2003057977A2 (en) * | 2002-01-10 | 2003-07-17 | Voith Fabrics Heidenheim Gmbh & Co. Kg. | Papermaking belts and industrial textiles with enhanced surface properties |
US6695992B2 (en) * | 2002-01-22 | 2004-02-24 | The University Of Akron | Process and apparatus for the production of nanofibers |
US6620905B1 (en) | 2002-02-23 | 2003-09-16 | National Starch And Chemical Investment Holding Corporation | Curable compositions containing benzoxazine |
JP4526004B2 (ja) * | 2002-03-05 | 2010-08-18 | 大日本印刷株式会社 | 希土類元素含有微粒子およびそれを用いた蛍光プローブ |
AU2003304348A1 (en) | 2002-03-15 | 2005-02-04 | The Trustees Of The University Of Pennsylvania | Fibrous composite for tissue engineering |
US7473031B2 (en) | 2002-04-01 | 2009-01-06 | Palo Alto Research Center, Incorporated | Resistive thermal sensing |
AU2003221788A1 (en) | 2002-04-30 | 2003-11-17 | University Of Maryland, Baltimore | Fluorescence sensing |
US8278055B2 (en) | 2002-05-01 | 2012-10-02 | Intel Corporation | Methods and device for analyte characterization |
US7744816B2 (en) | 2002-05-01 | 2010-06-29 | Intel Corporation | Methods and device for biomolecule characterization |
US20050019784A1 (en) * | 2002-05-20 | 2005-01-27 | Xing Su | Method and apparatus for nucleic acid sequencing and identification |
US7166133B2 (en) * | 2002-06-13 | 2007-01-23 | Kensey Nash Corporation | Devices and methods for treating defects in the tissue of a living being |
US7112615B2 (en) | 2002-07-22 | 2006-09-26 | Massachusetts Institute Of Technology | Porous material formation by chemical vapor deposition onto colloidal crystal templates |
US20050163821A1 (en) | 2002-08-02 | 2005-07-28 | Hsing-Wen Sung | Drug-eluting Biodegradable Stent and Delivery Means |
JP2005274587A (ja) | 2002-08-14 | 2005-10-06 | Konica Minolta Holdings Inc | 光像記録材料、その記録方法およびその製造方法 |
AU2003258414A1 (en) | 2002-08-23 | 2004-03-11 | Mcmaster University | Methods and compounds for controlling the morphology and shrinkage of silica derived from polyol-modified silanes |
DE10239762A1 (de) | 2002-08-26 | 2004-03-11 | Syntec Gesellschaft Für Chemie Und Technologie Der Informationsaufzeichnung Mbh | Hydrophile Schutzschicht |
AU2002337479A1 (en) | 2002-09-04 | 2004-03-29 | Hadasit Medical Research Services & Development Ltd. | Compositions comprising bone marrow cells, demineralized bone matrix and rtg polymers for use in the induction of bone and cartilage formation |
AU2003298998A1 (en) | 2002-09-05 | 2004-04-08 | Nanosys, Inc. | Oriented nanostructures and methods of preparing |
CA2498743A1 (en) | 2002-09-13 | 2004-03-25 | The University Of British Columbia | Calcium phosphate coated implantable medical devices and processes for making same |
AU2003275009A1 (en) | 2002-09-16 | 2004-04-30 | Biotechnology Research And Development Corporation | Methods for manufacturing polysaccharide derivatives |
WO2004027385A2 (en) * | 2002-09-20 | 2004-04-01 | The Children's Hospital Of Philadelphia | Engineering of material surfaces |
US20050032246A1 (en) * | 2002-11-14 | 2005-02-10 | Mcmaster University | Method of immobilizing membrane-associated molecules |
US20040222081A1 (en) | 2002-12-17 | 2004-11-11 | William Marsh Rice University | Use of microwaves to crosslink carbon nanotubes |
US20040222080A1 (en) | 2002-12-17 | 2004-11-11 | William Marsh Rice University | Use of microwaves to crosslink carbon nanotubes to facilitate modification |
US6858483B2 (en) * | 2002-12-20 | 2005-02-22 | Intel Corporation | Integrating n-type and p-type metal gate transistors |
TWI245079B (en) | 2002-12-30 | 2005-12-11 | Ind Tech Res Inst | Method for growing highly-ordered nanofibers |
US6955771B2 (en) | 2003-01-07 | 2005-10-18 | Aps Laboratory | Metal oxide sols as nanoscale additives for polymers |
CA2511180A1 (en) | 2003-01-17 | 2004-08-05 | Ciba Specialty Chemicals Holding Inc. | A process for the production of porous inorganic materials or a matrix material containing nanoparticles |
US7323530B2 (en) | 2003-01-27 | 2008-01-29 | Konica Minolta Holdings, Inc. | Transparent resin film, its manufacturing method, electronic display, liquid crystal display, organic EL display, and touch panel |
KR100493171B1 (ko) | 2003-02-08 | 2005-06-02 | 삼성에스디아이 주식회사 | 복합전해질막 및 이를 채용한 연료전지 |
CA2515651A1 (en) | 2003-02-11 | 2004-08-26 | Northwestern University | Methods and materials for nanocrystalline surface coatings and attachment of peptide amphiphile nanofibers thereon |
US20040162399A1 (en) * | 2003-02-14 | 2004-08-19 | Reddy Poreddy Narsi | Silicone-acrylate impact modifier |
WO2004076056A2 (en) | 2003-02-26 | 2004-09-10 | Lake Shore Cryotronics Inc. | Microfluidic chemical reactor for the manufacture of chemically-produced nanoparticles |
KR100401335B1 (en) | 2003-03-08 | 2003-10-10 | Mijitech Co Ltd | Metal nanoparticle surface-coated with silicon oxides and preparation thereof |
US20050038498A1 (en) * | 2003-04-17 | 2005-02-17 | Nanosys, Inc. | Medical device applications of nanostructured surfaces |
US7056409B2 (en) | 2003-04-17 | 2006-06-06 | Nanosys, Inc. | Structures, systems and methods for joining articles and materials and uses therefor |
US7074294B2 (en) | 2003-04-17 | 2006-07-11 | Nanosys, Inc. | Structures, systems and methods for joining articles and materials and uses therefor |
US20050221072A1 (en) | 2003-04-17 | 2005-10-06 | Nanosys, Inc. | Medical device applications of nanostructured surfaces |
US7985475B2 (en) | 2003-04-28 | 2011-07-26 | Nanosys, Inc. | Super-hydrophobic surfaces, methods of their construction and uses therefor |
US7013965B2 (en) * | 2003-04-29 | 2006-03-21 | General Electric Company | Organic matrices containing nanomaterials to enhance bulk thermal conductivity |
ATE346898T1 (de) | 2003-04-30 | 2006-12-15 | Nanosolutions Gmbh | Kern-mantel nanoteilchen für (f) ret- testverfahren |
US7255781B2 (en) | 2003-05-01 | 2007-08-14 | Ut-Battelle, Llc | Production of aligned microfibers and nanofibers and derived functional monoliths |
TWI427709B (zh) | 2003-05-05 | 2014-02-21 | Nanosys Inc | 用於增加表面面積之應用的奈米纖維表面 |
WO2005016824A2 (en) | 2003-05-05 | 2005-02-24 | The Research Foundation Of State University Of Newyork | Synthesis of nanoparticles by an emulsion-gas contacting process |
IL155866A0 (en) * | 2003-05-12 | 2003-12-23 | Yissum Res Dev Co | Responsive polymeric system |
FI20030780A0 (fi) | 2003-05-23 | 2003-05-23 | Bioxid Oy | Prepreg ja sen käyttö |
HUE031836T2 (en) * | 2003-06-24 | 2017-08-28 | Aspen Aerogels Inc | A method for producing gel films |
JP4465233B2 (ja) * | 2003-06-30 | 2010-05-19 | 三星電子株式会社 | 多官能性環状シロキサン化合物、この化合物から製造されたシロキサン系重合体及びこの重合体を用いた絶縁膜の製造方法 |
US8346482B2 (en) * | 2003-08-22 | 2013-01-01 | Fernandez Dennis S | Integrated biosensor and simulation system for diagnosis and therapy |
US8541054B2 (en) * | 2003-09-08 | 2013-09-24 | Honda Motor Co., Ltd | Methods for preparation of one-dimensional carbon nanostructures |
US6906003B2 (en) | 2003-09-18 | 2005-06-14 | Enernext, Llc | Method for sorption and desorption of molecular gas contained by storage sites of nano-filament laded reticulated aerogel |
US20050069718A1 (en) | 2003-09-30 | 2005-03-31 | Voss-Kehl Jessica L. | Printable insulating compositions and printable articles |
US20050100578A1 (en) * | 2003-11-06 | 2005-05-12 | Schmid Steven R. | Bone and tissue scaffolding and method for producing same |
WO2005069767A2 (en) | 2003-11-26 | 2005-08-04 | Cabot Corporation | Particulate absorbent materials and methods for making same |
US20050158763A1 (en) | 2003-12-19 | 2005-07-21 | Albena Ivanisevic | Aligned long DNA molecules on templates and methods for preparing |
JP2007524739A (ja) * | 2004-01-06 | 2007-08-30 | アスペン エアロゲルズ,インコーポレイティド | ケイ素結合線状ポリマーを含有するオルモシルエーロゲル |
FI116297B (fi) | 2004-01-07 | 2005-10-31 | Kemira Pigments Oy | Menetelmä pintojen käsittelemiseksi |
US8025960B2 (en) | 2004-02-02 | 2011-09-27 | Nanosys, Inc. | Porous substrates, articles, systems and compositions comprising nanofibers and methods of their use and production |
US7335250B2 (en) | 2004-02-06 | 2008-02-26 | Ivoclar Vivadent Ag | Dental composites based on X-ray-opaque mixed oxides prepared by flame spraying |
WO2005082277A1 (en) | 2004-02-18 | 2005-09-09 | Stanford University | Drug delivery systems using mesoporous oxide films |
US7189409B2 (en) | 2004-03-09 | 2007-03-13 | Inion Ltd. | Bone grafting material, method and implant |
US7744644B2 (en) | 2004-03-19 | 2010-06-29 | Boston Scientific Scimed, Inc. | Medical articles having regions with polyelectrolyte multilayer coatings for regulating drug release |
WO2005100642A1 (en) | 2004-04-13 | 2005-10-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Electrochemical deposition process and devices obtained by such process |
EP1586674A1 (en) | 2004-04-14 | 2005-10-19 | Nederlandse Organisatie voor Toegepast-Natuuurwetenschappelijk Onderzoek TNO | Coatings, and methods and devices for the manufacture thereof |
US7550519B2 (en) | 2004-04-21 | 2009-06-23 | Novartis Ag | Curable colored inks for making colored silicone hydrogel lenses |
US20050260118A1 (en) | 2004-05-20 | 2005-11-24 | Yunfeng Lu | Mesoporous carbon films and methods of preparation thereof |
US20050277710A1 (en) | 2004-06-14 | 2005-12-15 | Joyce Richard P | Tagged resin, method of making a tagged resin, and articles made therefrom |
US7884185B2 (en) * | 2004-07-28 | 2011-02-08 | University Of Delaware | Hydrogels and uses thereof |
SG119379A1 (en) * | 2004-08-06 | 2006-02-28 | Nippon Catalytic Chem Ind | Resin composition method of its composition and cured formulation |
US20060223965A1 (en) | 2005-03-31 | 2006-10-05 | Aspen Aerogels Inc. | High strength organic-inorganic hybrid gel materials |
US7674864B2 (en) * | 2005-12-23 | 2010-03-09 | Boston Scientific Scimed, Inc. | Polymeric hybrid precursors, polymeric hybrid precursor composite matrices, medical devices, and methods |
US7470466B2 (en) | 2005-12-23 | 2008-12-30 | Boston Scientific Scimed, Inc. | Nanoparticle structures and composite materials comprising a silicon-containing compound having a chemical linker that forms a non-covalent bond with a polymer |
US7953676B2 (en) * | 2007-08-20 | 2011-05-31 | Yahoo! Inc. | Predictive discrete latent factor models for large scale dyadic data |
-
2005
- 2005-12-23 US US11/318,027 patent/US8455088B2/en not_active Expired - Fee Related
-
2006
- 2006-12-20 JP JP2008547479A patent/JP4855481B2/ja not_active Expired - Fee Related
- 2006-12-20 EP EP20060850594 patent/EP1963553B1/en not_active Not-in-force
- 2006-12-20 CA CA 2634415 patent/CA2634415A1/en not_active Abandoned
- 2006-12-20 WO PCT/US2006/048576 patent/WO2007117296A2/en active Application Filing
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010519431A (ja) * | 2007-02-27 | 2010-06-03 | ピーピージー・インダストリーズ・オハイオ・インコーポレイテッド | 有機−無機電界紡糸繊維 |
JP2011178870A (ja) * | 2010-03-01 | 2011-09-15 | Kri Inc | 繊維補強複合材料、その製造方法、複合材料成形体および複合材料成形体の積層体 |
Also Published As
Publication number | Publication date |
---|---|
EP1963553A2 (en) | 2008-09-03 |
US8455088B2 (en) | 2013-06-04 |
CA2634415A1 (en) | 2007-10-18 |
EP1963553B1 (en) | 2014-04-02 |
WO2007117296A3 (en) | 2008-04-17 |
US20070144124A1 (en) | 2007-06-28 |
JP4855481B2 (ja) | 2012-01-18 |
WO2007117296A2 (en) | 2007-10-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4855481B2 (ja) | 紡糸ナノファイバー、医療用具および方法 | |
CA2634390C (en) | Nanoparticle precursor structures, nanoparticle structures, and composite materials | |
Ding et al. | Electrospun polymer biomaterials | |
Shin et al. | Advances in waterborne polyurethane-based biomaterials for biomedical applications | |
JP5379477B2 (ja) | 熱可塑性ポリマー組成物からなる医療器具 | |
Ghosal et al. | Poly (ester amides)(PEAs)–Scaffold for tissue engineering applications | |
JP2009505719A (ja) | 医療用デバイス用潤滑性複合物 | |
Khan et al. | A novel approach for the utilization of biocellulose nanofibres in polyurethane nanocomposites for potential applications in bone tissue implants | |
US20090306769A1 (en) | Medical balloon made with hybrid polymer-ceramic material and method of making and using the same | |
US11028215B2 (en) | Dopant-free conductive bioelastomers | |
Sharma et al. | Recent advances in polymer scaffolds for biomedical applications | |
Park et al. | Preparation and characterization of (polyurethane/nylon-6) nanofiber/(silicone) film composites via electrospinning and dip-coating | |
Sachan et al. | An overview on synthesis, properties and applications of polycaprolactone copolymers, blends & composites | |
US20220152271A1 (en) | Compositions and methods for 3d printed fibrous scaffolds with antimicrobial properties incorporating graphene oxide and poly(e-caprolactone) | |
US7674864B2 (en) | Polymeric hybrid precursors, polymeric hybrid precursor composite matrices, medical devices, and methods | |
Mouzakis et al. | Waterborne Polyurethanes for Tissue Engineering | |
Agrawal | Fabrication of chitosan based nanofibrous scaffold using free surface electrospinning for tissue engineering application | |
Erbogasto | Biocompatibility assessment of a sol-gel modified electrospun ventricular shunt catheter | |
Tan | Study of functional shape memory composites based on biocompatible electrospun nanofibers | |
Ghosal et al. | Electrospinning of polycaprolactone (PCL) with collagen coating from environmentally benign solvent: Preliminary physico-chemical studies for skin substitute |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20090304 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20091218 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20091218 |
|
TRDD | Decision of grant or rejection written | ||
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20110928 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20111003 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20111026 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20141104 Year of fee payment: 3 |
|
R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |