JP2008517991A5 - - Google Patents

Download PDF

Info

Publication number
JP2008517991A5
JP2008517991A5 JP2007538524A JP2007538524A JP2008517991A5 JP 2008517991 A5 JP2008517991 A5 JP 2008517991A5 JP 2007538524 A JP2007538524 A JP 2007538524A JP 2007538524 A JP2007538524 A JP 2007538524A JP 2008517991 A5 JP2008517991 A5 JP 2008517991A5
Authority
JP
Japan
Prior art keywords
effective amount
therapeutically effective
pld
combination
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007538524A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008517991A (ja
JP4554684B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2005/050189 external-priority patent/WO2006046080A2/fr
Publication of JP2008517991A publication Critical patent/JP2008517991A/ja
Publication of JP2008517991A5 publication Critical patent/JP2008517991A5/ja
Application granted granted Critical
Publication of JP4554684B2 publication Critical patent/JP4554684B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2007538524A 2004-10-26 2005-10-26 抗癌治療 Active JP4554684B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62216304P 2004-10-26 2004-10-26
PCT/GB2005/050189 WO2006046080A2 (fr) 2004-10-26 2005-10-26 Traitements anticancereux

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009219607A Division JP2009292850A (ja) 2004-10-26 2009-09-24 抗癌治療

Publications (3)

Publication Number Publication Date
JP2008517991A JP2008517991A (ja) 2008-05-29
JP2008517991A5 true JP2008517991A5 (fr) 2008-11-13
JP4554684B2 JP4554684B2 (ja) 2010-09-29

Family

ID=36096124

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007538524A Active JP4554684B2 (ja) 2004-10-26 2005-10-26 抗癌治療
JP2009219607A Pending JP2009292850A (ja) 2004-10-26 2009-09-24 抗癌治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009219607A Pending JP2009292850A (ja) 2004-10-26 2009-09-24 抗癌治療

Country Status (27)

Country Link
US (1) US20090117176A1 (fr)
EP (1) EP1827500B1 (fr)
JP (2) JP4554684B2 (fr)
KR (1) KR101287918B1 (fr)
CN (1) CN101119750B (fr)
AT (1) ATE430586T1 (fr)
AU (1) AU2005298364B2 (fr)
BR (1) BRPI0518250A2 (fr)
CA (1) CA2582452C (fr)
CY (1) CY1110329T1 (fr)
DE (1) DE602005014380D1 (fr)
DK (1) DK1827500T3 (fr)
ES (1) ES2326825T3 (fr)
HK (1) HK1107766A1 (fr)
HR (1) HRP20090345T1 (fr)
IL (1) IL182352A (fr)
MX (1) MX2007004744A (fr)
NO (1) NO328958B1 (fr)
NZ (1) NZ554765A (fr)
PL (1) PL1827500T3 (fr)
PT (1) PT1827500E (fr)
RS (1) RS50822B (fr)
RU (1) RU2359700C2 (fr)
SI (1) SI1827500T1 (fr)
UA (1) UA87877C2 (fr)
WO (1) WO2006046080A2 (fr)
ZA (1) ZA200703396B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY164077A (en) * 1999-05-13 2017-11-30 Pharma Mar Sa Compositions and uses of et743 for treating cancer
MXPA02011319A (es) 2000-05-15 2003-06-06 Pharma Mar Sa Analogos antitumorales de ecteinascidina 743.
CZ20031327A3 (cs) * 2000-11-06 2003-11-12 Pharma Mar, S. A. Užití ET-743 k výrobě léků pro účinnou protinádorovou léčbu
GB0117402D0 (en) * 2001-07-17 2001-09-05 Pharma Mar Sa New antitumoral derivatives of et-743
GB0202544D0 (en) 2002-02-04 2002-03-20 Pharma Mar Sa The synthesis of naturally occuring ecteinascidins and related compounds
CA2544320A1 (fr) 2003-11-13 2005-06-02 Pharma Mar, S.A.U. Utilisation d'une combinaison d'et-743 et de 5-fluorouracile pour traiter le cancer
CN1897949A (zh) * 2003-11-14 2007-01-17 马尔药品公司 包含使用et-743和紫杉醇来治疗癌症的联合疗法
SI1658848T1 (sl) 2004-10-29 2007-12-31 Pharma Mar Sa Formulacije vsebujoäśe ekteinascidin in disaharid
GB0522082D0 (en) * 2005-10-31 2005-12-07 Pharma Mar Sa Formulations
KR101376634B1 (ko) * 2006-06-19 2014-03-27 더 존스 홉킨스 유니버시티 리포좀아제에 의한 치료제의 종양­특이적 전달
AU2008313634A1 (en) * 2007-10-19 2009-04-23 Pharma Mar, S.A. Prognostic molecular markers for ET-743 treatment
US11110108B2 (en) * 2016-09-27 2021-09-07 Vertex Pharmaceuticals Incorporated Method for treating cancer using a combination of DNA-damaging agents and DNA-PK inhibitors
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام
RU2657835C1 (ru) * 2017-11-28 2018-06-15 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский технологический университет "МИСиС" Способ получения системы для доставки противоопухолевого препарата в клетки опухоли

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5149804A (en) * 1990-11-30 1992-09-22 The Board Of Trustees Of The University Of Illinois Ecteinascidins 736 and 722
US5089273A (en) * 1986-06-09 1992-02-18 Board Of Trustees Of The University Of Illinois Ecteinascidins 729, 743, 745, 759A, 759B and 770
US5256663A (en) * 1986-06-09 1993-10-26 The Board Of Trustees Of The University Of Illinois Compositions comprising ecteinascidins and a method of treating herpes simplex virus infections therewith
DE3635711A1 (de) * 1986-10-21 1988-04-28 Knoll Ag 5-nitrobenzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
US5478932A (en) * 1993-12-02 1995-12-26 The Board Of Trustees Of The University Of Illinois Ecteinascidins
US20040059112A1 (en) * 1994-02-18 2004-03-25 Rinehart Kenneth L. Ecteinascidins
GB9508195D0 (en) * 1995-04-20 1995-06-07 Univ British Columbia Novel biologically active compounds and compositions,their use and derivation
US5721362A (en) * 1996-09-18 1998-02-24 President And Fellows Of Harvard College Process for producing ecteinascidin compounds
US5985876A (en) * 1997-04-15 1999-11-16 Univ Illinois Nucleophile substituted ecteinascidins and N-oxide ecteinascidins
US6124293A (en) * 1998-04-06 2000-09-26 The Board Of Trustees Of The University Of Illinois Semi-synthetic ecteinascidins
US6124292A (en) * 1998-09-30 2000-09-26 President And Fellows Of Harvard College Synthetic analogs of ecteinascidin-743
MY164077A (en) * 1999-05-13 2017-11-30 Pharma Mar Sa Compositions and uses of et743 for treating cancer
MY130271A (en) * 1999-05-14 2007-06-29 Pharma Mar Sa Hemisynthetic method and new compounds
US20020028237A1 (en) * 2000-04-20 2002-03-07 Colbern Gail T. Method for reducing toxicity of a cytotoxic agent
US7247892B2 (en) * 2000-04-24 2007-07-24 Taylor Geoff W Imaging array utilizing thyristor-based pixel elements
US7420051B2 (en) * 2000-05-15 2008-09-02 Pharma Mar, S.A. Synthetic process for the manufacture of an ecteinaschidin compound
MXPA02011319A (es) * 2000-05-15 2003-06-06 Pharma Mar Sa Analogos antitumorales de ecteinascidina 743.
EP1356097A2 (fr) * 2000-08-11 2003-10-29 City of Hope Agent anti neoplasique et-743 inhibant la trans-activation par sxr
KR100834138B1 (ko) * 2000-10-31 2008-06-02 파르마 마르, 에스.에이. 카할라리드 에프
CZ20031327A3 (cs) * 2000-11-06 2003-11-12 Pharma Mar, S. A. Užití ET-743 k výrobě léků pro účinnou protinádorovou léčbu
EP1368034A1 (fr) * 2001-03-06 2003-12-10 Bristol-Myers Squibb Company Procede et forme posologique pour le traitement de tumeurs par administration de tegafur, d'uracile, d'acide folinique, de paclitaxel et de carboplatine
KR100915741B1 (ko) * 2001-06-15 2009-09-04 코너스톤 파마슈티칼스 표적 조직 및 세포를 치료하기에 유용한 나노입자를함유하는 약제학적 및 진단학적 조성물
CA2462502A1 (fr) * 2001-10-19 2003-05-15 Pharma Mar, S.A. Utilisation amelioree de compose anti-tumoral dans le traitement des cancers
US20040019027A1 (en) * 2002-04-12 2004-01-29 Barry Forman Method of treating cerebrotendinous xanthomatosis
AU2003253954A1 (en) * 2002-07-16 2004-02-02 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Support bra for ultrasonic breast scanner
GB0312407D0 (en) * 2003-05-29 2003-07-02 Pharma Mar Sau Treatment
GB0324201D0 (en) * 2003-10-15 2003-11-19 Pharma Mar Sau Improved antitumoral combinations
CA2544320A1 (fr) * 2003-11-13 2005-06-02 Pharma Mar, S.A.U. Utilisation d'une combinaison d'et-743 et de 5-fluorouracile pour traiter le cancer
CN1897949A (zh) * 2003-11-14 2007-01-17 马尔药品公司 包含使用et-743和紫杉醇来治疗癌症的联合疗法
GB0326486D0 (en) * 2003-11-14 2003-12-17 Pharma Mar Sau Combination treatment
US20050129752A1 (en) * 2003-12-15 2005-06-16 Tty Biopharm Limited Company Use and manufacturing process for liposomal doxorubicin pharmaceutical composition
WO2006005602A2 (fr) * 2004-07-09 2006-01-19 Pharma Mar, S.A. Marqueurs moleculaires de pronostic
SI1658848T1 (sl) * 2004-10-29 2007-12-31 Pharma Mar Sa Formulacije vsebujoäśe ekteinascidin in disaharid
US20090170860A1 (en) * 2005-11-25 2009-07-02 Pharma Mar, S.A., Sociedad Unipersonal Use of PARP-1 Inhibitors
US20080075772A1 (en) * 2006-04-13 2008-03-27 Lawrence Solomon Pharmaceutical compositions having novel scoring patterns and methods of using those compositions
EP2023931A2 (fr) * 2006-05-12 2009-02-18 Pharma Mar S.A. Traitements anticancéreux avec une combinaison de docétaxel et ecteinascidine

Similar Documents

Publication Publication Date Title
JP2008517991A5 (fr)
CA2582452A1 (fr) Doxorubicine liposomale pegylee en combinaison avec l'ecteinascidine 743
JP6404242B2 (ja) がんの治療のための併用療法としてのエリブリンおよびレンバチニブの使用
JP2008520544A5 (ja) 癌関連疲労の治療または予防のための医薬の製造への使用方法
HRP20170056T2 (hr) Terapija male učestalosti glatiramer acetatom
RU2010133489A (ru) Применение ингибиторов гамма-секретазы для лечения рака
JP2009539769A5 (fr)
IL145487A0 (en) Apomorphine and sildenafil composition
RU2012106620A (ru) Комбинации и способы введения терапевтических средств и комбинированной терапии
JP2010519224A5 (fr)
JP2002544231A5 (fr)
WO2005094899A8 (fr) Traitement de cancers par un antisens anti-clusterine
KR101900520B1 (ko) 복합 조성물
JP2010526837A5 (fr)
JP2006514092A5 (fr)
RU2007101695A (ru) Лекарственный препарат для лечения сахарного диабета на основе экзенатида и даларгина, применение и способ лечения
IL194500A0 (en) Peptide substance enhancing capillaries resistance, pharmaceutical composition on its base and method of its application
ES2267841T3 (es) Uso de una derivado de alfa-halogeno-acriloil distamicina para la preparacion de un medicamento para el tratamiento del cancer.
JP2003514025A5 (fr)
JP2005508963A5 (fr)
CA2474430A1 (fr) Polytherapie combinant un agent thrombolytique et du levosimendane pour le traitement de l'infractus aigu du myocarde
CA2450915A1 (fr) Utilisation de levosimendane et d'un antagoniste du recepteur beta-adrenergique pour traiter les defaillances cardiaques
JP2015510945A5 (fr)
CA2516458A1 (fr) Utilisation de composes de kahalalide pour la fabrication d'un medicament pour le traitement de psoriasis
RU2010140888A (ru) Улучшенные противораковые терапии