JP2007534410A - 椎間板プロテーゼ - Google Patents
椎間板プロテーゼ Download PDFInfo
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- JP2007534410A JP2007534410A JP2007510151A JP2007510151A JP2007534410A JP 2007534410 A JP2007534410 A JP 2007534410A JP 2007510151 A JP2007510151 A JP 2007510151A JP 2007510151 A JP2007510151 A JP 2007510151A JP 2007534410 A JP2007534410 A JP 2007534410A
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- intervertebral disc
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
- A61F2/4425—Intervertebral or spinal discs, e.g. resilient made of articulated components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30331—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementarily-shaped recess, e.g. held by friction fit
- A61F2002/30362—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementarily-shaped recess, e.g. held by friction fit with possibility of relative movement between the protrusion and the recess
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30383—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by laterally inserting a protrusion, e.g. a rib into a complementarily-shaped groove
- A61F2002/3039—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by laterally inserting a protrusion, e.g. a rib into a complementarily-shaped groove with possibility of relative movement of the rib within the groove
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30518—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements with possibility of relative movement between the prosthetic parts
- A61F2002/30528—Means for limiting said movement
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30563—Special structural features of bone or joint prostheses not otherwise provided for having elastic means or damping means, different from springs, e.g. including an elastomeric core or shock absorbers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30604—Special structural features of bone or joint prostheses not otherwise provided for modular
- A61F2002/30616—Sets comprising a plurality of prosthetic parts of different sizes or orientations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30621—Features concerning the anatomical functioning or articulation of the prosthetic joint
- A61F2002/30649—Ball-and-socket joints
- A61F2002/3065—Details of the ball-shaped head
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30621—Features concerning the anatomical functioning or articulation of the prosthetic joint
- A61F2002/30649—Ball-and-socket joints
- A61F2002/30654—Details of the concave socket
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
- A61F2/4425—Intervertebral or spinal discs, e.g. resilient made of articulated components
- A61F2002/443—Intervertebral or spinal discs, e.g. resilient made of articulated components having two transversal endplates and at least one intermediate component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0033—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
Description
Claims (20)
- 第1のプレート(1)と、第2のプレート(2)と、少なくとも第1および第2のプレート(1、2)の1つに対して少なくとも回転する可動のコア(3)とを含む、少なくとも3つの部品を備える椎間板プロテーゼであって、
コア(3)が、第1のプレート(1)の相補的曲面表面の少なくとも一部に接触する曲面表面と、第2のプレート(2)およびコア(3)の周辺部近くに置かれた、第2のオスおよびメス型協働手段(23、33)の実質的に平坦な少なくとも一部に接触する実質的に平坦な表面とを有し、
協働手段が、実質的に平坦な表面に実質的に平行な軸に沿って、コアが第2のプレートに対して並進することを制限または防止することを可能にし、かつ実質的に平坦な表面に実質的に垂直な軸まわりに、コアが第2のプレートに対して回転運動することを制限または防止することを可能にし、
コア(3)の曲面表面(30)の頂部(31)が、コア(3)の曲面表面(30)の幾何的中心(32)に対して少なくとも一方向に中心がずれている、椎間板プロテーゼ。 - 患者が運動しないときのコア(3)の静止位置が、プレートが脊椎に固定されたときに、第1のプレート(1)および第2のプレート(2)の対称軸が整列することと、コア(3)の曲面表面(30)に相補的な第1のプレート(1)の曲面表面(10)が、第1および第2のプレート(1、2)の対称軸をコア(3)の曲面表面(30)の中心のずれた頂部(31)に整列させ、これにより、コア(3)をコアの曲面表面(30)の頂部(31)の中心ずれの方向と反対方向に移動させることとにより、コア(3)の曲面表面(30)の頂部(31)の中心ずれの方向と反対方向に移動させ、
この結果、コア(3)にある協働手段(33)と、第2のプレート(2)にある協働手段(23)が結合するようになり、該結合が、コア(3)をコアの曲面表面(30)の頂部(31)の中心ずれの方向と反対方向に変位するのを制限する、請求項1に記載の椎間板プロテーゼ。 - 同じプレート(1、2)が、異なるコア(3)と組み合わせ可能であり、コア(3)間の差が、コア(3)の曲面表面(30)の中心(32)に対する曲面表面(30)の頂部(31)の位置の差である、請求項1に記載の椎間板プロテーゼ。
- 同じコア(3)が異なるプレート(1、2)と組み合わせ可能であり、プレート間の差は、プレートの上側面と下側面を表す中心平面間の角度の差である、請求項1に記載の椎間板プロテーゼ。
- 上側プレート(1)の上側面と第2のプレート(2)の下側面との間の角度が、第2のプレート(2)および/または第1のプレート(1)の上側面と下側面を表す中心平面が角度を生成することによるか、または協働手段(23、33)によって、プレート(1、2)の少なくとも1つに傾斜を課す位置のまわりのコア(3)の移動を限定することによるかのいずれかにより課されることができる、請求項1に記載の椎間板プロテーゼ。
- 同じプレート(1、2)が、様々な厚みおよび/またはサイズのコア(3)と組み合わせ可能である、請求項1に記載の椎間板プロテーゼ。
- コア(3)の曲面表面(30)が、コア(3)の凸形上側面であり、第1のプレート(1)の曲面表面(10)が、上側プレート(1)の下側面の凹形部分である、請求項1に記載の椎間板プロテーゼ。
- 各オス型協働手段(33)の寸法を、各メス型協働手段(23)の寸法よりわずかに小さくすることにより、コア(3)と第2のプレート(2)との間に小さい間隙を形成する、請求項1に記載の椎間板プロテーゼ。
- 各オス型手段(33)の寸法を、各メス型手段(23)の寸法と実質的に同一にすることにより、コア(3)と第2のプレート(2)との間の間隙をなくす、請求項1に記載の椎間板プロテーゼ。
- コア(3)が、ポリエチレンで形成される、請求項1に記載の椎間板プロテーゼ。
- 第1のプレート(1)および第2のプレート(2)が、金属で形成される、請求項1に記載の椎間板プロテーゼ。
- 第2のプレート(2)が、コア(3)のオス型手段(33)と協働するメス型手段(23)を備える、請求項1に記載の椎間板プロテーゼ。
- コア(3)のオス型手段(33)が、コア(3)の2つの側端に配置された2つの接触プレートであり、第2のプレート(2)のメス型手段(23)が、第2のプレート(2)の2つの側方向端それぞれに対で配置された4つの壁面である、請求項12に記載の椎間板プロテーゼ。
- 第2のプレート(2)のメス型協働手段(23)を形成する壁面が、プロテーゼの中心方向に曲がっており、これにより、コア(3)のオス型手段(33)の少なくとも一部を覆い、かつコアが持ち上がるのを防止する、請求項13に記載の椎間板プロテーゼ。
- 第2のプレート(2)が、コア(3)のメス型手段と協働するオス型手段を備えている、請求項1に記載の椎間板プロテーゼ。
- 第2のプレート(2)のオス型手段が、プロテーゼの両端上の相互に対向する2つの接触プレートであり、コア(3)のメス型手段が、2つの凹所である、請求項15に記載の椎間板プロテーゼ。
- 第2のプレート(2)のオス型手段が、プロテーゼの両端近くで相互に対向する2つの壁面であり、コア(3)のメス型手段が、凹所である、請求項15に記載の椎間板プロテーゼ。
- 第2のプレート(2)のオス型手段が、プロテーゼの内側方向に曲がりかつプロテーゼの両端上で相互に対向する2つのニブであり、コア(3)のメス型手段が、2つの凹所である、請求項15に記載の椎間板プロテーゼ。
- ニブの少なくとも1つが、開口に収まる接触プレートに置き換えられ、接触プレートに、開口を貫通するピンによってラグを固定する、請求項18に記載の椎間板プロテーゼ。
- 第1のプレート(1)は、上側面の少なくとも一部が***しており、脊椎の形状に適合する、請求項1に記載の椎間板プロテーゼ。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0404501A FR2869528B1 (fr) | 2004-04-28 | 2004-04-28 | Prothese de disque intervertebral |
FR04/04501 | 2004-04-28 | ||
PCT/IB2005/001151 WO2005104996A1 (en) | 2004-04-28 | 2005-04-28 | Intervertebral disc prothesis |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012004188A Division JP2012115681A (ja) | 2004-04-28 | 2012-01-12 | 椎間板プロテーゼ |
Publications (2)
Publication Number | Publication Date |
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JP2007534410A true JP2007534410A (ja) | 2007-11-29 |
JP4986846B2 JP4986846B2 (ja) | 2012-07-25 |
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JP (2) | JP4986846B2 (ja) |
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CN (1) | CN1964681B (ja) |
BR (1) | BRPI0510391A (ja) |
CA (1) | CA2564987C (ja) |
FR (1) | FR2869528B1 (ja) |
IL (1) | IL178842A (ja) |
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RU (1) | RU2361546C2 (ja) |
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US20090157188A1 (en) | 2009-06-18 |
US8002835B2 (en) | 2011-08-23 |
JP4986846B2 (ja) | 2012-07-25 |
US20170071754A1 (en) | 2017-03-16 |
US9889017B2 (en) | 2018-02-13 |
ZA200608883B (en) | 2008-11-26 |
MXPA06012459A (es) | 2007-01-31 |
CN1964681A (zh) | 2007-05-16 |
KR20070004069A (ko) | 2007-01-05 |
US8974532B2 (en) | 2015-03-10 |
KR101197655B1 (ko) | 2012-11-07 |
CA2564987A1 (en) | 2005-11-10 |
WO2005104996A1 (en) | 2005-11-10 |
FR2869528A1 (fr) | 2005-11-04 |
RU2006141843A (ru) | 2008-06-10 |
BRPI0510391A (pt) | 2007-11-13 |
JP2012115681A (ja) | 2012-06-21 |
US20050246024A1 (en) | 2005-11-03 |
CN1964681B (zh) | 2010-06-02 |
US7494508B2 (en) | 2009-02-24 |
IL178842A (en) | 2011-11-30 |
US20180235770A1 (en) | 2018-08-23 |
US20120053693A1 (en) | 2012-03-01 |
EP1750624B1 (en) | 2021-03-10 |
RU2361546C2 (ru) | 2009-07-20 |
US9445915B2 (en) | 2016-09-20 |
CA2564987C (en) | 2013-05-28 |
IL178842A0 (en) | 2007-03-08 |
US20150245918A1 (en) | 2015-09-03 |
EP1750624A1 (en) | 2007-02-14 |
FR2869528B1 (fr) | 2007-02-02 |
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