JP2007504921A - 光活性殺菌方法 - Google Patents
光活性殺菌方法 Download PDFInfo
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- JP2007504921A JP2007504921A JP2006530524A JP2006530524A JP2007504921A JP 2007504921 A JP2007504921 A JP 2007504921A JP 2006530524 A JP2006530524 A JP 2006530524A JP 2006530524 A JP2006530524 A JP 2006530524A JP 2007504921 A JP2007504921 A JP 2007504921A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C1/00—Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design
- A61C1/08—Machine parts specially adapted for dentistry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0624—Apparatus adapted for a specific treatment for eliminating microbes, germs, bacteria on or in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C1/00—Dental machines for boring or cutting ; General features of dental machines or apparatus, e.g. hand-piece design
- A61C1/08—Machine parts specially adapted for dentistry
- A61C1/088—Illuminating devices or attachments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N5/0603—Apparatus for use inside the body for treatment of body cavities
- A61N2005/0606—Mouth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
- A61N2005/0652—Arrays of diodes
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Pathology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Dentistry (AREA)
- Epidemiology (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
Description
(635nmでの)放出エネルギー=電力×時間
=0.1×120
=12ジュール
i. レーザではなくて、フィルタがかけられた白光源またはLED(発光ダイオード)光源の使用。
象牙質およびエナメル質の両方を通過しての伝達を改善するために約660nmのより長い波長、表面の病気のために約625nmのより短い波長を用いるとともに、高出力装置の有用性を活用する。
ii. 小径ファイバとの連結を回避するために、歯に外部から光を照射する。
iii. より長い波長光の照射と、活発な希釈化が起こり得る部位への適用とを考慮して、感光性物質の濃度を(200μg/mlまで)高めて使用する。
11…放射部
12…歯
13…歯根管
20…LEDアレイ
21…光ガイド
22…反射面または鏡面
23…歯
24…光線
25…病変
Claims (12)
- 所定の波長および電力で光を発生する光源と、使用時に前記光を前記光源から歯の少なくとも1つの外側面に導く光伝送手段とを備えた歯科用装置。
- 前記光源は、1つの発光ダイオード、または、発光ダイオードのアレイを含むことを特徴とする請求項1に記載の装置。
- 前記光は、550〜690nm、より好ましくは600〜680nm、さらに好ましくは625〜660nmの波長を有することを特徴とする請求項1または2に記載の装置。
- 前記光伝送手段は、少なくとも1つの光ガイドを含むことを特徴とする請求項1ないし3のいずれかに記載の装置。
- 前記光伝送手段は、使用時に歯の2つの外側面に光を照射する一対の光ガイドを含むことを特徴とする請求項4に記載の装置。
- 単一の光源を備えるとともに、前記光源からの光を前記一対の光ガイドに分配する光分配手段をさらに備えることを特徴とする請求項5に記載の装置。
- 前記光伝送手段はほぼ平行に延びる一対の光ガイドからなり、各光ガイドは前記光ガイドに沿った光伝送方向に対して45°に傾斜した反射面を設けた末端部を有し、前記光ガイドの前記反射面は、各光ガイドから放射された光が平行であるが逆向きになるように対向していることを特徴とする請求項5または6に記載の装置。
- 補助光源と補助光伝送手段とをさらに備え、前記補助光伝送手段は歯の穴に挿入可能な形状および寸法に形成されていることを特徴とする請求項1ないし7のいずれかに記載の装置。
- 組織、損傷または病変に感光性化合物を接触させ、前記組織、損傷または病変に前記感光性化合物で吸収される波長の光を照射する、口腔または口腔内の損傷もしくは病変を殺菌する方法において、
前記光は、1つの発光ダイオード、または、発光ダイオードのアレイを含む光源によって生成されることを特徴とする方法。 - 前記光源は、請求項1ないし8のいずれかに記載の装置に含まれるものであることを特徴とする請求項9に記載の方法。
- 前記感光性化合物は、トルイジンブルーO、メチレンブルー、ジメチレンブルー、または、瑠璃色塩化物から選択される少なくとも1つの感光性物質であることを特徴とする請求項9または10に記載の方法。
- 前記感光性物質はトルイジンブルーOであることを特徴とする請求項11に記載の方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0311950.0A GB0311950D0 (en) | 2003-05-23 | 2003-05-23 | Photo-activated disinfection |
PCT/GB2004/002187 WO2004103471A1 (en) | 2003-05-23 | 2004-05-21 | Photo-activated disinfection |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2007504921A true JP2007504921A (ja) | 2007-03-08 |
Family
ID=9958702
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006530524A Pending JP2007504921A (ja) | 2003-05-23 | 2004-05-21 | 光活性殺菌方法 |
Country Status (12)
Country | Link |
---|---|
US (1) | US20080214530A1 (ja) |
EP (1) | EP1641533A1 (ja) |
JP (1) | JP2007504921A (ja) |
KR (1) | KR20060032589A (ja) |
CN (1) | CN1812822B (ja) |
AU (1) | AU2004241781B2 (ja) |
BR (1) | BRPI0410627A (ja) |
CA (1) | CA2526657C (ja) |
GB (1) | GB0311950D0 (ja) |
MX (1) | MXPA05012681A (ja) |
NZ (1) | NZ543968A (ja) |
WO (1) | WO2004103471A1 (ja) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050053895A1 (en) | 2003-09-09 | 2005-03-10 | The Procter & Gamble Company Attention: Chief Patent Counsel | Illuminated electric toothbrushes emitting high luminous intensity toothbrush |
US20060200212A1 (en) * | 2005-02-17 | 2006-09-07 | Brawn Peter R | Light therapy device for treatment of bone disorders and biostimulation of bone and soft tissue |
US20070248930A1 (en) | 2005-02-17 | 2007-10-25 | Biolux Research Ltd. | Light therapy apparatus and methods |
DE202006016025U1 (de) * | 2006-10-16 | 2007-02-08 | Arentz, Jochen, Dr.med.dent. | Vorrichtung zur antibakteriellen Behandlung eines Patienten |
US20100256125A1 (en) * | 2009-04-06 | 2010-10-07 | Zila Pharmaceuticals, Inc. | Use of improved toluidine blue in photodynamic therapy |
US9642687B2 (en) | 2010-06-15 | 2017-05-09 | The Procter & Gamble Company | Methods for whitening teeth |
WO2012075584A1 (en) | 2010-12-08 | 2012-06-14 | Biolux Research Limited | Methods and apparatuses useful for regulating bone remodeling or tooth movement using light therapy, a functional appliance, and/or vitamin d |
JP6484235B2 (ja) | 2013-10-22 | 2019-03-13 | バイオルックス リサーチ リミテッド | 口腔内光治療装置及びその使用方法 |
CN108136196B (zh) | 2015-07-28 | 2020-07-17 | 诺欧生物有限责任公司 | 用于对一氧化氮的光疗调节的***和方法 |
US20210128935A1 (en) | 2015-07-28 | 2021-05-06 | Know Bio, Llc | Phototherapeutic light for treatment of pathogens |
US12011611B2 (en) | 2020-03-19 | 2024-06-18 | Know Bio, Llc | Illumination devices for inducing biological effects |
US11147984B2 (en) | 2020-03-19 | 2021-10-19 | Know Bio, Llc | Illumination devices for inducing biological effects |
US11986666B2 (en) | 2020-03-19 | 2024-05-21 | Know Bio, Llc | Illumination devices for inducing biological effects |
US11654294B2 (en) | 2021-03-15 | 2023-05-23 | Know Bio, Llc | Intranasal illumination devices |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60203248A (ja) * | 1984-03-28 | 1985-10-14 | サイテク株式会社 | 口歯清浄具 |
JPS6397175A (ja) * | 1986-10-15 | 1988-04-27 | 森 敬 | 歯茎治療照射光照射装置 |
JPH02185242A (ja) * | 1988-12-21 | 1990-07-19 | Demetoron Res Corp | 歯の修復に用いる光ガイド装置 |
JPH03112549A (ja) * | 1989-09-28 | 1991-05-14 | Matsutani Seisakusho Co Ltd | 根管内レーザー光照射プローブ |
JPH0928715A (ja) * | 1995-07-14 | 1997-02-04 | Sumitomo Electric Ind Ltd | レーザプローブおよびそれを用いたレーザ医療装置 |
WO1998006456A1 (en) * | 1996-08-08 | 1998-02-19 | Light Sciences Limited Partnership | Method and apparatus to treat gingival and periodontal disease |
JP2000070292A (ja) * | 1998-08-27 | 2000-03-07 | Agency Of Ind Science & Technol | 歯科用光照射装置 |
WO2000074587A1 (en) * | 1999-06-04 | 2000-12-14 | Denfotex Ltd. | Method and apparatus for filling a dental root canal |
US20030097122A1 (en) * | 2001-04-10 | 2003-05-22 | Ganz Robert A. | Apparatus and method for treating atherosclerotic vascular disease through light sterilization |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH103979A (de) * | 1923-03-16 | 1924-03-17 | Steinberg Edgar | Ansatz für Bestrahlungsapparate, insbesondere zur Bestrahlung in Körperhöhlen liegender Stellen. |
US1590283A (en) * | 1924-10-20 | 1926-06-29 | De Forest B Catlin | Therapeutic device |
WO1993021992A1 (en) * | 1992-04-30 | 1993-11-11 | Institute Of Dental Surgery | Laser treatment |
US5420768A (en) * | 1993-09-13 | 1995-05-30 | Kennedy; John | Portable led photocuring device |
US6251127B1 (en) * | 1997-08-25 | 2001-06-26 | Advanced Photodynamic Technologies, Inc. | Dye treatment solution and photodynamic therapy and method of using same |
US6208788B1 (en) * | 1998-07-29 | 2001-03-27 | Ultradent Products, Inc. | Apparatus and methods for concentrating light through fiber optic funnels coupled to dental light guides |
EP1171053B1 (en) * | 1999-04-16 | 2007-01-17 | Denfotex Ltd. | Apparatus for treating dental caries |
CA2297476A1 (en) * | 2000-01-21 | 2001-07-21 | Neks Recherche & Developpement Inc. | System for detection of dental tartar, e.g. subgingival tartar |
GB2360459B (en) * | 2000-03-23 | 2002-08-07 | Photo Therapeutics Ltd | Therapeutic light source and method |
DE10138071A1 (de) * | 2001-08-03 | 2003-02-27 | Georg Knott | Bestrahlungsvorrichtung |
GB0619588D0 (en) * | 2006-10-04 | 2006-11-29 | Denfotex Ltd | Photo-activated disinfection |
-
2003
- 2003-05-23 GB GBGB0311950.0A patent/GB0311950D0/en not_active Ceased
-
2004
- 2004-05-21 EP EP04734285A patent/EP1641533A1/en not_active Ceased
- 2004-05-21 BR BRPI0410627-0A patent/BRPI0410627A/pt not_active IP Right Cessation
- 2004-05-21 AU AU2004241781A patent/AU2004241781B2/en not_active Ceased
- 2004-05-21 US US10/558,026 patent/US20080214530A1/en not_active Abandoned
- 2004-05-21 CA CA2526657A patent/CA2526657C/en not_active Expired - Fee Related
- 2004-05-21 CN CN2004800177260A patent/CN1812822B/zh not_active Expired - Fee Related
- 2004-05-21 KR KR1020057022429A patent/KR20060032589A/ko active IP Right Grant
- 2004-05-21 NZ NZ543968A patent/NZ543968A/en unknown
- 2004-05-21 JP JP2006530524A patent/JP2007504921A/ja active Pending
- 2004-05-21 MX MXPA05012681A patent/MXPA05012681A/es not_active Application Discontinuation
- 2004-05-21 WO PCT/GB2004/002187 patent/WO2004103471A1/en active Application Filing
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60203248A (ja) * | 1984-03-28 | 1985-10-14 | サイテク株式会社 | 口歯清浄具 |
JPS6397175A (ja) * | 1986-10-15 | 1988-04-27 | 森 敬 | 歯茎治療照射光照射装置 |
JPH02185242A (ja) * | 1988-12-21 | 1990-07-19 | Demetoron Res Corp | 歯の修復に用いる光ガイド装置 |
JPH03112549A (ja) * | 1989-09-28 | 1991-05-14 | Matsutani Seisakusho Co Ltd | 根管内レーザー光照射プローブ |
JPH0928715A (ja) * | 1995-07-14 | 1997-02-04 | Sumitomo Electric Ind Ltd | レーザプローブおよびそれを用いたレーザ医療装置 |
WO1998006456A1 (en) * | 1996-08-08 | 1998-02-19 | Light Sciences Limited Partnership | Method and apparatus to treat gingival and periodontal disease |
JP2000070292A (ja) * | 1998-08-27 | 2000-03-07 | Agency Of Ind Science & Technol | 歯科用光照射装置 |
WO2000074587A1 (en) * | 1999-06-04 | 2000-12-14 | Denfotex Ltd. | Method and apparatus for filling a dental root canal |
US20030097122A1 (en) * | 2001-04-10 | 2003-05-22 | Ganz Robert A. | Apparatus and method for treating atherosclerotic vascular disease through light sterilization |
Also Published As
Publication number | Publication date |
---|---|
CA2526657A1 (en) | 2004-12-02 |
WO2004103471A1 (en) | 2004-12-02 |
US20080214530A1 (en) | 2008-09-04 |
AU2004241781B2 (en) | 2010-06-24 |
GB0311950D0 (en) | 2003-06-25 |
CN1812822B (zh) | 2010-06-30 |
CN1812822A (zh) | 2006-08-02 |
EP1641533A1 (en) | 2006-04-05 |
BRPI0410627A (pt) | 2006-06-20 |
MXPA05012681A (es) | 2006-02-02 |
CA2526657C (en) | 2012-04-17 |
AU2004241781A1 (en) | 2004-12-02 |
NZ543968A (en) | 2008-12-24 |
KR20060032589A (ko) | 2006-04-17 |
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