JP2006325828A - Skin test sheet for surface measurement - Google Patents

Skin test sheet for surface measurement Download PDF

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JP2006325828A
JP2006325828A JP2005152212A JP2005152212A JP2006325828A JP 2006325828 A JP2006325828 A JP 2006325828A JP 2005152212 A JP2005152212 A JP 2005152212A JP 2005152212 A JP2005152212 A JP 2005152212A JP 2006325828 A JP2006325828 A JP 2006325828A
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skin
indicator
surface measurement
test sheet
sheet
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Shusuke Yokoi
秀輔 横井
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Life Care Giken Inc
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Abstract

<P>PROBLEM TO BE SOLVED: To provide a skin test sheet for surface measurement for testing the amount of moisture evaporation and/or secretory components, etc. on a broad area of skin. <P>SOLUTION: The sheet consists of a sheet-shaped indicator holder 12 containing an indicator to indicate specified conditions of the skin, a diffusion prevention film 14 which is attached to one side of the indicator holder 12 and permeable to steam, and an adhesive layer 16 formed at a part of a side of the diffusion prevention film 14, which is the other side of the one where the indicator holder 12 is attached. The diffusion prevention film is made of a vapor-permeable resin film. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

この発明は頬や顔全体等の広い面積の皮膚の水分蒸発量や体液ｐH、皮膚の保湿性や、その他の状態を検査する面測定用皮膚検査シートに関する。   The present invention relates to a skin measurement sheet for surface measurement for inspecting moisture evaporation of body skin, body fluid pH, skin moisture retention, and other conditions over a wide area such as a cheek or the entire face.

通常、皮膚は適度な水分保持状態が好ましく、皮膚表面は弱酸性に保たれ、健康な皮膚はアルカリに対して中和能を供えている。しかし、老化の進行や皮膚疾患などによって皮膚は徐々に乾燥しやすくなって皮膚水分蒸発量が高くなり、また皮膚のアルカリ中和能が低下し、皮脂量が低下する傾向を示す。   Usually, the skin is preferably kept in a proper moisture state, the skin surface is kept weakly acidic, and healthy skin is capable of neutralizing alkali. However, due to the progress of aging, skin diseases and the like, the skin gradually becomes easy to dry, the amount of skin water evaporation increases, the skin's alkali neutralization ability decreases, and the amount of sebum tends to decrease.

そこで、広い面積で変色（濃淡）から皮膚表面のＴＥＷＬ値の分布を調べ、ＴＥＷＬ値が高い部分は皮膚の老化の原因であり、この部位はシミ・しわになりやすいので、この結果からシミ・しわの発生を予測することができ、また皮膚の老化予防等のスキンケアをすることが可能となる。   Therefore, the distribution of TEWL values on the skin surface is examined from discoloration (shading) over a wide area, and the part with a high TEWL value is the cause of skin aging, and this part is likely to cause spots and wrinkles. The occurrence of wrinkles can be predicted, and skin care such as prevention of skin aging can be performed.

従来、皮膚水分を簡単に知る手段として、特許文献１に開示されている本願出願人による皮膚水分保持機能試験シート等がある。これは、粘着剤により皮膚に貼付される透明フィルムと、透明フィルムの粘着剤側の面に設けられ塩化コバルトを吸着させた１枚又は複数枚の塩化コバルト含浸ろ紙を有している。透明フィルムには、塩化コバルトが吸湿により反応する発色の色見本が設けられ、１枚又は複数枚の塩化コバルト含浸ろ紙は、異なる湿度で塩化コバルトの変色反応が開始されるように調整されている。
特開２００４−２３６７９４号公報 特表２００４−５３５８５９号公報 Conventionally, as means for easily knowing skin moisture, there is a skin moisture retention function test sheet by the applicant of the present application disclosed in Patent Document 1. This has a transparent film stuck on the skin with an adhesive and one or more cobalt chloride impregnated filter papers provided on the adhesive side of the transparent film and adsorbing cobalt chloride. The transparent film is provided with a color sample for color development in which cobalt chloride reacts by moisture absorption, and one or more cobalt chloride impregnated filter papers are adjusted so that the discoloration reaction of cobalt chloride is started at different humidity. .
JP 2004-236794 A Special table 2004-535859 gazette

シミの原因は年齢や精神的ストレスの他に化粧品・洗剤・食物・紫外線などによる物理的刺激があげられ、角質の劣化したＴＥＷＬ値の高い部位はシミやしわが出来やすいことが知られている。この劣化の初期に適切なケアをすることによりシミ・しわを予防することができる。 上記従来の技術の場合、シートの中心に小形の塩化コバルト含浸ろ紙が設けられ、塩化コバルト含浸ろ紙が覆っている近傍の皮膚を検査してその周囲の状態を推測するものであり、広い範囲のＴＥＷＬ値の分布を同時に測定して皮膚の状態を検査するものではなかった。また、特許文献２に開示されているような化粧品の評価シートは皺の状態を転写する目的で提案されている。単に大形の塩化コバルト含浸ろ紙や評価シートを皮膚に貼付して試験すると、皮膚の水分が塩化コバルト含浸ろ紙等の皮膚側の表面で拡散し、水分の分布が均一化され、皮膚の部分的なTEWL値の分布を調べることが出来ない。   Causes of stains include physical stimulation caused by cosmetics, detergents, food, UV rays, etc. in addition to age and mental stress, and it is known that spots with high TEWL values that have deteriorated keratin are susceptible to spots and wrinkles. . Spots and wrinkles can be prevented by taking appropriate care early in the deterioration. In the case of the above prior art, a small cobalt chloride impregnated filter paper is provided at the center of the sheet, and the surrounding skin covered by the cobalt chloride impregnated filter paper is inspected to estimate the surrounding condition. The TEWL value distribution was not simultaneously measured to examine the skin condition. A cosmetic evaluation sheet as disclosed in Patent Document 2 has been proposed for the purpose of transferring the state of wrinkles. When a large cobalt chloride-impregnated filter paper or evaluation sheet is simply applied to the skin and tested, the moisture in the skin diffuses on the skin-side surface of the cobalt chloride-impregnated filter paper, etc. I can't check the distribution of TEWL values.

この発明は、上記従来の技術の問題点に鑑みてなされたものであり、皮膚の広い範囲のTEWL値の分布等を直接検査する面測定用皮膚検査シートを提供することを目的とする。   The present invention has been made in view of the above-described problems of the prior art, and an object thereof is to provide a skin measurement sheet for surface measurement that directly inspects the distribution of TEWL values in a wide range of skin.

表皮は角質層・透明層・顆粒層・有棘層・基底層から構成され、角質は基底層から角質層に徐々に移動する。この角質によって肌の状態が異なり、特に肌の水分は老化の過程で角質のバリア機能の低下がすすむと共に低下する。このためＴＥＷＬの面積測定により微小部位の老化の進行の度合いを知ることが出来る。また、この測定によってＴＥＷＬ値の高い部位に対してその進行の度合いに応じて予防的な治療が可能となる。 The epidermis is composed of the stratum corneum, transparent layer, granule layer, spiny layer, and basal layer, and the stratum corneum moves gradually from the basal layer to the stratum corneum. The skin condition differs depending on the keratin, and the water content of the skin particularly decreases as the keratin barrier function decreases during the aging process. For this reason, it is possible to know the degree of progress of aging of the minute part by measuring the area of TEWL. In addition, this measurement makes it possible to preventively treat a site with a high TEWL value depending on the degree of progression.

この発明は、所定の皮膚状態を表示する指示薬が含まれているシート状の指示薬保持体と、前記指示薬保持体の片面に取り付けられ水透過性を有する拡散防止膜と、前記指示薬保持体とは反対側の面の一部に形成された粘着剤層が設けられている面測定用皮膚検査シートである。   The present invention includes a sheet-like indicator holder that contains an indicator that displays a predetermined skin state, a diffusion barrier film that is attached to one side of the indicator holder and has water permeability, and the indicator holder. It is a skin test sheet for surface measurement provided with an adhesive layer formed on a part of the opposite surface.

前記拡散防止膜は、ポリエチレン等の透湿性を有する樹脂フィルムで作られている。ポリエチレンの他に、例えばポリビニールアルコール、ポリオレフイン、ポリプロピレン、ポリエステル、ポリ塩化ビニル、ポリ塩化ビニリデン、ナイロン、ポリウレタン等でも良く、水分子の透過性があればよい。樹脂フィルムの種類と厚さを選ぶことにより水分の透湿速度を適宜調節することができる。また、透過速度を高めるためにはコロナ放電処理、機械的な開孔などの物理的な方法も有効である。   The diffusion preventing film is made of a resin film having moisture permeability such as polyethylene. In addition to polyethylene, for example, polyvinyl alcohol, polyolefin, polypropylene, polyester, polyvinyl chloride, polyvinylidene chloride, nylon, polyurethane and the like may be used as long as water molecules are permeable. By selecting the type and thickness of the resin film, the moisture transmission rate of moisture can be adjusted as appropriate. In order to increase the transmission speed, physical methods such as corona discharge treatment and mechanical opening are also effective.

また、前記指示薬は、水分によって変色する薬剤、たとえば塩化コバルトの他に、ＢＣＴ（ブルムクレゾールパープル）、ＭＲ（メチルレッド）、ＣＲＰ（クロールフェノールレッド）、ＰＰ（フェノールパープル）等のｐＨ指示薬でもよい。また皮脂に反応する指示薬でも良い。そして、指示薬の種類や検出する成分に合わせて、拡散防止膜の水蒸気透過性の数値を適宜設定する。   Further, the indicator may be a pH indicator such as BCT (bulum cresol purple), MR (methyl red), CRP (chlorphenol red), PP (phenol purple), etc., in addition to an agent that changes color with moisture, for example, cobalt chloride. . Moreover, the indicator which reacts with sebum may be sufficient. And according to the kind of indicator and the component to detect, the water-vapor-permeable numerical value of a diffusion prevention film is set suitably.

皮膚表面から蒸散する経表皮水分喪失（ＴＥＷＬ）は角質バリア機能の指標となり、バリア機能の低下と共にＴＥＷＬ値は高くなる。また、このＴＥＷＬ値を皮膚の細部について調べることにより、老化・シミ・しわの発生を予測することが出来る。   Transepidermal water loss (TEWL) transpiration from the skin surface is an index of the keratin barrier function, and the TEWL value increases as the barrier function decreases. Further, by examining the TEWL value for details of the skin, it is possible to predict the occurrence of aging, spots and wrinkles.

本発明の面測定用皮膚検査シートは、被験者の皮膚状態を広い範囲で直接検査して、目的の成分の濃度分布を正確に検知することができ、皮膚疾患の予防や治療、また美容を目的とする処置を、皮膚の問題発生部位を0.5〜1ｍｍ2の面積で特定して皮膚の状態を診断し、老化等の予測が出来るので、効率良く治療することができる。 The skin measurement sheet for surface measurement of the present invention can directly detect the skin condition of a subject in a wide range and accurately detect the concentration distribution of the target component, and is intended for prevention and treatment of skin diseases and cosmetics. Since the skin condition can be diagnosed by identifying the skin problem occurrence site with an area of 0.5 to 1 mm 2 and aging can be predicted, the treatment can be efficiently performed.

以下、この発明の実施形態について図面に基づいて説明する。図１、図２はこの発明の一実施形態を示すもので、この実施形態の面測定用皮膚検査シート１０は、水分量で色が変化する指示薬保持体１２が設けられている。指示薬保持体１２は、水分により変色する指示薬が、支持体であるろ紙に塗布又は含浸して作られている。ここで指示薬保持体１２に使われる指示薬は、塩化コバルトである。なお指示薬は、塩化コバルトに限定されず、水と反応して変色する物質、例えばカルボン酸になりやすいラクトン又は無水物、あるいは水に溶解して活性化され導電性を有するもの、単に水溶性塩を溶解させることによって不溶性塩の色が生じる電解質などである。指示薬保持体１２は、高分子樹脂に指示薬を溶解又は分散させ、透湿性のあるフィルムに形成したものでも良い。   Hereinafter, embodiments of the present invention will be described with reference to the drawings. FIG. 1 and FIG. 2 show an embodiment of the present invention, and the surface measurement skin test sheet 10 of this embodiment is provided with an indicator holder 12 whose color changes with the amount of moisture. The indicator holder 12 is made by applying or impregnating an indicator that changes color with moisture onto a filter paper as a support. Here, the indicator used for the indicator holder 12 is cobalt chloride. The indicator is not limited to cobalt chloride, but is a substance that reacts with water and changes color, such as a lactone or anhydride that easily becomes a carboxylic acid, or an activated and conductive substance that dissolves in water, or a water-soluble salt. An electrolyte in which the color of an insoluble salt is produced by the dissolution of. The indicator holder 12 may be formed by dissolving or dispersing an indicator in a polymer resin and forming a moisture-permeable film.

指示薬保持体１２の一方の側面１２ａには、拡散防止膜１４が設けられている。拡散防止膜１４は、水蒸気透過性を有するポリエチレンフィルム等の樹脂フィルムであり、適度な柔軟性を有している。樹脂フィルムとしてはポリエチレンの他に、例えばポリビニールアルコール、ポリオレフイン、ポリプロピレン、ポリエステル、ポリ塩化ビニル、ポリ塩化ビニリデン、ナイロン、ポリウレタン等でも良い。測定感度や指示薬の種類等に合わせて、拡散防止膜１４の水蒸気透過性を適宜設定することができる。   A diffusion preventing film 14 is provided on one side surface 12 a of the indicator holder 12. The diffusion prevention film 14 is a resin film such as a polyethylene film having water vapor permeability, and has appropriate flexibility. In addition to polyethylene, the resin film may be, for example, polyvinyl alcohol, polyolefin, polypropylene, polyester, polyvinyl chloride, polyvinylidene chloride, nylon, polyurethane, or the like. The water vapor permeability of the diffusion preventing film 14 can be appropriately set according to the measurement sensitivity, the kind of indicator, and the like.

拡散防止膜１４の、指示薬保持体１２と反対側の側面１４ａには、拡散防止膜１４の周縁部に沿って、ほぼ一定の所定幅、例えば５ｍｍ程度の幅に、粘着剤層１６が設けられている。粘着剤層１６は、例えばアクリル系粘着剤またはＳＩＳ等の合成ゴム粘着剤である。   A pressure-sensitive adhesive layer 16 is provided on the side surface 14a of the diffusion preventing film 14 opposite to the indicator holder 12 so as to have a substantially constant predetermined width, for example, about 5 mm, along the peripheral edge of the diffusion preventing film 14. ing. The pressure-sensitive adhesive layer 16 is, for example, an acrylic pressure-sensitive adhesive or a synthetic rubber pressure-sensitive adhesive such as SIS.

拡散防止膜１４の、粘着剤層１６側の面には、剥離フィルム１８が、粘着剤層１６に周縁部を粘着されて取り付けられている。   A release film 18 is attached to the surface of the diffusion prevention film 14 on the pressure-sensitive adhesive layer 16 side with its peripheral edge adhered to the pressure-sensitive adhesive layer 16.

面測定用皮膚検査シート１０の形状は、ゆるやかに湾曲した繭形で、例えば目元等に貼付して測定しやすい形状に形成されている。なお、面測定用皮膚検査シート１０の形状は、適宜その他の形状に形成することができる。例えば、三日月形、１０ｃｍ×１０ｃｍ程度の矩形、頬等への貼付に適する円形、顔型のフェースマスク状に形成されたもの、腰部に適する楕円形等でも良い。さらに、例えば５〜１０ｃｍ×２ｍ程度のロール状でも良く、この場合、床ずれやアトピー性皮膚炎の部位など広い範囲の測定の際に、必要な寸法に裁断して使用することができる。   The shape of the surface measurement skin test sheet 10 is a gently curved saddle shape, for example, a shape that is easy to measure by being attached to the eyes or the like. In addition, the shape of the surface measurement skin test sheet 10 can be appropriately formed in other shapes. For example, a crescent shape, a rectangle of about 10 cm × 10 cm, a circle suitable for sticking to a cheek, a face-shaped face mask, an ellipse suitable for the waist, and the like may be used. Further, for example, a roll shape of about 5 to 10 cm × 2 m may be used, and in this case, it can be used by cutting to a necessary dimension in measurement in a wide range such as a bed slip or a site of atopic dermatitis.

次に、面測定用皮膚検査シート１０の使用方法について説明する。まず面測定用皮膚検査シート１０から剥離フィルム１８を剥がし、粘着剤層１６を皮膚に押し付けて貼着して、拡散防止膜１４を皮膚に密着させる。この状態で、皮膚から蒸発した水分は、拡散防止膜１４により周囲への拡散が阻止され、皮膚表面に対してほぼ直角に、拡散防止膜１４内を透過する。透過した水分は指示薬保持体１２に吸収され、指示薬の色を変化させる。そして所定時間貼付した後、面測定用皮膚検査シート１０の指示薬保持体１２の色を色見本等と照合し、皮膚水分の蒸発量の濃度分布を調べる。   Next, a method of using the surface measurement skin test sheet 10 will be described. First, the release film 18 is peeled off from the skin measurement sheet 10 for surface measurement, and the pressure-sensitive adhesive layer 16 is pressed against and adhered to the skin, so that the diffusion preventing film 14 is adhered to the skin. In this state, moisture evaporated from the skin is prevented from diffusing to the surroundings by the diffusion preventing film 14 and permeates through the diffusion preventing film 14 at a substantially right angle to the skin surface. The permeated moisture is absorbed by the indicator holder 12 and changes the color of the indicator. After affixing for a predetermined time, the color of the indicator holder 12 of the surface measurement skin test sheet 10 is checked against a color sample or the like, and the concentration distribution of the evaporation amount of skin moisture is examined.

判定は、水分蒸発量（ｍｇ/ｃｍ２/ｈｒ）の色見本と比較して行う。例えば、ここでは４段階で判定を行い、各段階は、−（０〜４ｍｇ/ｃｍ２/ｈｒ）、＋（５〜１０ｍｇ/ｃｍ２/ｈｒ）、＋２（１１〜２０ｍｇ/ｃｍ２/ｈｒ）、＋３（２１〜３０ｍｇ/ｃｍ２/ｈｒ）とした。図面では便宜上、水分透過性をパターンの濃さで示しその境界を仮想線で区別したが、実際は、連続した濃度の変化として表れる。TEWL値の更に高い精度での分析方法としてはデジタルカメラ等の光学的映像による解析は有効である。 The determination is made in comparison with a color sample of the amount of moisture evaporation (mg / cm 2 / hr). For example, here, the determination is made in four stages, and each stage has − (0 to 4 mg / cm 2 / hr), + (5 to 10 mg / cm 2 / hr), +2 (11 to 20 mg / cm 2 / hr). , +3 (21-30 mg / cm 2 / hr). In the drawing, for the sake of convenience, the moisture permeability is shown by the darkness of the pattern, and the boundary thereof is distinguished by a virtual line. As an analysis method with higher accuracy of TEWL value, analysis using optical images from a digital camera or the like is effective.

この実施形態の面測定用皮膚検査シート１０によれば、被験者の皮膚状態を広い範囲で直接検査し、正確に皮膚の水分蒸発量の濃度分布を判定することができる。そして、この結果を基にして水分の足りない部分に保湿成分を塗布する等、部分的できめ細かい処置を行うことができ、皮膚の老化その他のトラブルを効率的に予防することができる。   According to the surface measurement skin test sheet 10 of this embodiment, the skin condition of the subject can be directly examined in a wide range, and the concentration distribution of the moisture evaporation amount of the skin can be accurately determined. And based on this result, it is possible to perform partial and detailed treatments such as applying a moisturizing component to a portion lacking moisture, and efficiently prevent skin aging and other troubles.

さらに、本発明の面測定用皮膚検査シート１０を用いることによりしみや皺の予防、床ずれの発生予測、アトピー性皮膚炎やアレルギー性疾患部位の検出を行うことができる。そして、早期の予防的治療が可能になり、より適切なスキンケアが可能となる。また、皮膚の細部の状態、例えば１ｍｍ程度の位置の違いでのバリア機能の有無、高低を数値で分析できるので、適切な治療を施すことができる。美容の面でも、皮膚の状態を正確に知ることにより手入れ方法の判断に役立てることができ、老化等の進行の度合いを０．５〜１ｍｍ２の精度で調べることができる。 Further, by using the surface measurement skin test sheet 10 of the present invention, it is possible to prevent spots and wrinkles, predict the occurrence of bed slips, and detect atopic dermatitis and allergic disease sites. In addition, early preventive treatment is possible, and more appropriate skin care is possible. In addition, since it is possible to numerically analyze the state of details of the skin, for example, the presence / absence of the barrier function and the height depending on the position difference of about 1 mm, appropriate treatment can be performed. In terms of beauty, knowing the state of the skin accurately can be used to determine the care method, and the degree of progression such as aging can be examined with an accuracy of 0.5 to 1 mm 2 .

また、面測定用皮膚検査シート１０の変色反応の濃度分布を調べることにより、貼付部位のＴＥＷＬ（皮膚水分蒸発率）値を面で測定し、ＴＥＷＬ値の数値の分布を調べることができる。その結果から微細な部位のＴＥＷＬ値の差が変色の度合いで調べることができる。   Further, by examining the concentration distribution of the discoloration reaction of the surface measurement skin test sheet 10, the TEWL (skin moisture evaporation rate) value of the applied site can be measured on the surface, and the numerical value distribution of the TEWL value can be examined. From the result, the difference in TEWL value of a minute part can be examined by the degree of discoloration.

さらにこの実施形態の面測定用皮膚検査シート１０は、面測定用皮膚検査シート１０の皮膚に接触する面に、拡散防止膜１４が設けられているため、水分蒸発量が高い部分の水分が周囲に拡散することを防ぎ、指示薬保持体１２の色の濃度分布の境界が明確となり、正確に判定することができる。また、面測定用皮膚検査シート１０は製造が容易であり、コストも安価で経済的に優れている。   Further, the surface measurement skin test sheet 10 of this embodiment is provided with the diffusion prevention film 14 on the surface of the surface measurement skin test sheet 10 that comes into contact with the skin. The boundary of the color density distribution of the indicator holder 12 becomes clear and can be determined accurately. Further, the surface measurement skin test sheet 10 is easy to manufacture, is inexpensive and is economically superior.

なお、この発明の面測定用皮膚検査シートは上記実施形態に限定されるものではない。例えば、水分を検査するもの以外に、ｐＨを調べるものでも良い。ｐＨ指示薬として、ＢＣＴ（ブルムクレゾールパープル）、ＭＲ（メチルレッド）、ＣＲＰ（クロールフェノールレッド）、ＰＰ（フェノールパープル）等を用いる。そのほか、皮膚から発する体臭成分に反応する指示薬を用いたり、皮膚表面の脂質に反応する指示薬を用いたりして、体臭や脂質の度合いを検査するものでも良い。水分、ｐＨ、脂質等の検査結果を組み合わせて総合的に皮膚の状態を把握してもよい。拡散防止膜の水蒸気透過性の数値は、指示薬の種類や、検出する成分に合わせて適宜設定するものである。また、面測定用皮膚検査シートの形状は、自由に変更可能であり、貼付部位は、顔、首、腰、手、ひじ、膝、足、かかと等、自由に選択可能である。そして必要に応じて粘着剤層の面積や取り付ける位置と形状を変更しても良い。   In addition, the skin test sheet for surface measurement of this invention is not limited to the said embodiment. For example, in addition to the test for moisture, a test for pH may be used. As a pH indicator, BCT (bulum cresol purple), MR (methyl red), CRP (chlorphenol red), PP (phenol purple) or the like is used. In addition, an indicator that reacts with body odor components emitted from the skin or an indicator that reacts with lipids on the skin surface may be used to examine the degree of body odor or lipid. The skin condition may be comprehensively grasped by combining test results such as moisture, pH, and lipid. The numerical value of water vapor permeability of the diffusion preventing film is appropriately set according to the kind of indicator and the component to be detected. Further, the shape of the surface measurement skin test sheet can be freely changed, and the application site can be freely selected from the face, neck, waist, hand, elbow, knee, foot, heel, and the like. And you may change the area of an adhesive layer, the position and shape to attach as needed.

この発明の実施形態の面測定用皮膚検査シートの正面図である。It is a front view of the skin test sheet for surface measurement of the embodiment of this invention. この実施形態の検査シートの縦断面図である。It is a longitudinal cross-sectional view of the inspection sheet of this embodiment. この実施形態の検査シートの使用状態を示す正面図である。It is a front view which shows the use condition of the test | inspection sheet of this embodiment.

符号の説明Explanation of symbols

１０ 面測定用皮膚検査シート
１２ 指示薬保持体
１４ 拡散防止膜
１６ 粘着剤層
１８ 剥離フィルム DESCRIPTION OF SYMBOLS 10 Skin measurement sheet | seat 12 for surface measurement Indicator holder 14 Diffusion prevention film 16 Adhesive layer 18 Release film

Claims (4)

所定の皮膚状態を表示する指示薬が含まれているシート状の指示薬保持体と、前記指示薬保持体の片面に取り付けられ水分透過性を有する拡散防止膜と、指示薬保持体とは反対側の面の一部に形成された粘着剤層が設けられていることを特徴とする面測定用皮膚検査シート。   A sheet-shaped indicator holder containing an indicator for displaying a predetermined skin state, a diffusion barrier film attached to one side of the indicator holder and having moisture permeability, and a surface opposite to the indicator holder A skin test sheet for surface measurement, characterized in that a part of the pressure-sensitive adhesive layer is provided. 前記拡散防止膜は樹脂フィルムで作られていることを特徴とする請求項１記載の面測定用皮膚検査シート。   The skin test sheet for surface measurement according to claim 1, wherein the diffusion preventing film is made of a resin film. 前記指示薬は、水分を検知する塩化コバルトであることを特徴とする請求項１記載の面測定用皮膚検査シート。   The skin test sheet for surface measurement according to claim 1, wherein the indicator is cobalt chloride that detects moisture. 前記指示薬は、ｐH指示薬であることを特徴とする請求項１記載の面測定用皮膚検査シート。
The skin test sheet for surface measurement according to claim 1, wherein the indicator is a pH indicator.
JP2005152212A 2005-05-25 2005-05-25 Skin test sheet for surface measurement Pending JP2006325828A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014163824A (en) * 2013-02-26 2014-09-08 Chiba Univ Skin function determination marker, skin function-determining method, and search method of oral skin function-improving agent
CN106691516A (en) * 2017-03-06 2017-05-24 桂林市威诺敦医疗器械有限公司 Skin test instrument with humidity detection function

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014163824A (en) * 2013-02-26 2014-09-08 Chiba Univ Skin function determination marker, skin function-determining method, and search method of oral skin function-improving agent
CN106691516A (en) * 2017-03-06 2017-05-24 桂林市威诺敦医疗器械有限公司 Skin test instrument with humidity detection function
CN106691516B (en) * 2017-03-06 2023-05-05 桂林市威诺敦医疗器械有限公司 Skin tester with humidity detection function

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