JP2003212750A - Gel composition and emulsified composition - Google Patents
Gel composition and emulsified compositionInfo
- Publication number
- JP2003212750A JP2003212750A JP2002013761A JP2002013761A JP2003212750A JP 2003212750 A JP2003212750 A JP 2003212750A JP 2002013761 A JP2002013761 A JP 2002013761A JP 2002013761 A JP2002013761 A JP 2002013761A JP 2003212750 A JP2003212750 A JP 2003212750A
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- Prior art keywords
- gel composition
- general formula
- fatty acid
- acid ester
- composition
- Prior art date
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Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、一般式１に示され
る化合物および／またはその塩とポリグリセリン脂肪酸
エステルを含有することを特徴とするゲル組成物および
乳化組成物に関するものである。より詳しくは、一般式
１に示される化合物および／またはその塩とポリグリセ
リン脂肪酸エステルを含有することにより、油の乳化能
が高く、経時安定性に優れたゲル組成物および乳化組成
物に関する。TECHNICAL FIELD The present invention relates to a gel composition and an emulsion composition containing a compound represented by the general formula 1 and / or a salt thereof and a polyglycerol fatty acid ester. More specifically, the present invention relates to a gel composition and an emulsified composition having a high oil emulsifying ability and excellent temporal stability by containing a compound represented by the general formula 1 and / or a salt thereof and a polyglycerin fatty acid ester.
【０００２】[0002]
【従来の技術】近年、人的な安全性の面で天然またはそ
れ由来の界面活性物質を乳化剤として使用する研究がな
されてきた。その様な中で、Ｂａｃｉｌｌｕｓ ｓｕｂ
ｔｉｌｉｓ等に代表される微生物により発酵する過程で
分泌生産される一般式１に示す界面活性物質も安全性の
高い天然の乳化剤として期待され、様々な乳化方法の研
究がなされてきた。2. Description of the Related Art In recent years, studies have been made on the use of natural or derived surface-active substances as emulsifiers in terms of human safety. In such a situation, Bacillus sub
The surface-active substance represented by the general formula 1 secreted and produced in the process of fermentation by a microorganism represented by tilis and the like is also expected as a highly safe natural emulsifier, and various emulsification methods have been studied.
【０００３】[0003]
【発明が解決しようとする課題】この様な状況の中で、
化粧品等の皮膚外用剤に求められる機能は天然物由来の
界面活性剤、いわゆるバイオサーファクタントの界面活
性を利用した系で、そのゲル組成物および乳化組成物を
得ること、さらには、そのゲル組成物に水を加えること
により物理的に弱い攪拌力で効率よく経時的に安定で微
細な乳化粒子を形成させることである。[Problems to be Solved by the Invention] In such a situation,
The function required for external preparations for skin such as cosmetics is a system utilizing the surfactant of natural products, that is, the so-called biosurfactant, to obtain a gel composition and an emulsion composition thereof, and further, the gel composition thereof. By adding water to the mixture, it is possible to efficiently form stable and fine emulsified particles over time with a physically weak stirring force.
【０００４】[0004]
【課題を解決するための手段】本発明者等は、かかる実
情に鑑み鋭意検討した結果、一般式１に示される化合物
および／またはその塩とポリグリセリン脂肪酸エステル
を含有することにより、自己組織体形成能が高く、経時
安定性に優れており、更には油の乳化能が高いゲル組成
物および乳化組成物の発明を完成するに至った。Means for Solving the Problems The inventors of the present invention have made extensive studies in view of the above-mentioned circumstances, and as a result, by containing a compound represented by the general formula 1 and / or a salt thereof and a polyglycerin fatty acid ester, self-organization The inventors have completed the invention of a gel composition and an emulsified composition having high forming ability, excellent stability over time, and high oil emulsifying ability.
【０００５】すなわち、本発明のゲル組成物および乳化
組成物は一般式１に示される化合物および／またはその
塩とポリグリセリン脂肪酸エステルを含有するものであ
り、自己組織体形成能が高く、経時安定性に優れた組成
物である。That is, the gel composition and the emulsified composition of the present invention contain the compound represented by the general formula 1 and / or a salt thereof and polyglycerin fatty acid ester, have a high self-organizing ability and are stable over time. It is a composition having excellent properties.
【０００６】以下、本発明の構成について詳述する。The structure of the present invention will be described in detail below.
【０００７】本発明で用いられる一般式１の物質はＢａ
ｃｉｌｌｕｓ ｓｕｂｔｉｌｉｓ等に代表される微生物
により発酵する過程で分泌生産される、いわゆるバイオ
サーファクタントと称されるものである。The substance of the general formula 1 used in the present invention is Ba
It is a so-called biosurfactant, which is secreted and produced in the process of fermentation by a microorganism represented by Cillus subtilis.
【０００８】具体的にはＲ１はアミノ酸であり、多くは
Ｌ−ロイシン、Ｌ−イソロイシン、Ｌ−バリン等から選
ばれる。Ｒ２は炭素鎖Ｃ８〜Ｃ２２のアルキルであり、
直鎖状、分岐状、環状、さらには飽和、不飽和いずれで
もよい。Ｒ３は水素または、塩も使用可能でありナトリ
ウム塩、カリウム塩等のアルカリ金属塩が用いられる。
さらには、それらの混合系でも良い。Specifically, R 1 is an amino acid, and most of them are selected from L-leucine, L-isoleucine, L-valine and the like. R 2 is C 8 -C 22 alkyl having a carbon chain,
It may be linear, branched, cyclic, and saturated or unsaturated. As R 3 , hydrogen or a salt can be used, and an alkali metal salt such as sodium salt or potassium salt is used.
Further, a mixed system thereof may be used.
【０００９】本発明で用いられる一般式１に示される化
合物は、好ましくは、Ｒ１がＬ−ロイシン、Ｒ２が一般
式２、Ｒ３がナトリウムである。In the compound represented by the general formula 1 used in the present invention, preferably, R 1 is L-leucine, R 2 is the general formula 2, and R 3 is sodium.
【００１０】一般式１に示される化合物の含有量は特に
限定されるものではないが、０．１〜１０重量％とする
ことが好ましく、０．１重量％未満では経時安定性が劣
る場合がありり、１０重量％を超えて含有することは可
能であるが経済的でない。The content of the compound represented by the general formula 1 is not particularly limited, but it is preferably 0.1 to 10% by weight, and if less than 0.1% by weight, stability with time may be poor. However, it is possible to contain more than 10% by weight, but it is not economical.
【００１１】本発明で用いられるポリグリセリン脂肪酸
エステルは特に限定されるものではないが、好ましくは
ポリグリセリン部の重合度が４以上であり、脂肪酸部が
Ｃ８〜Ｃ２２の炭素鎖であり、飽和、不飽和、直鎖、分
岐等が挙げられ、これから選ばれる１種または２種以上
を組み合わせて含有してもよい。The polyglycerin fatty acid ester used in the present invention is not particularly limited, but preferably, the polyglycerin part has a degree of polymerization of 4 or more, and the fatty acid part is a C 8 to C 22 carbon chain, Examples thereof include saturated, unsaturated, straight-chain, branched, and the like, and one or more selected from these may be contained in combination.
【００１２】ポリグリセリン脂肪酸エステルの含有量は
特に限定されるものではないが、０．１〜５重量％とす
ることが好ましく、０．１重量％未満では経時安定性が
劣る場合があり、５重量％を超えて含有すること使用感
が好ましくない。The content of the polyglycerin fatty acid ester is not particularly limited, but it is preferably 0.1 to 5% by weight, and if it is less than 0.1% by weight, the stability with time may be poor. It is unfavorable to use if the content is more than wt%.
【００１３】本発明で用いられるゲル化法は通常知られ
ている方法で調整できるが、好ましくはまず一般式１に
示される化合物および／またはその塩とポリグリセリン
脂肪酸エステルとグリセリンを混合し（Ｘ部）、次にＸ
部を撹拌しながら油相を徐々に加える方法である。好ま
しくはＸ部および油相を５０〜８０℃に加熱する方法で
ある。The gelation method used in the present invention can be adjusted by a generally known method, but preferably, the compound represented by the general formula 1 and / or a salt thereof, a polyglycerin fatty acid ester and glycerin are mixed (X Part), then X
This is a method of gradually adding the oil phase while stirring the parts. Preferred is a method of heating part X and the oil phase to 50 to 80 ° C.
【００１４】具体的にはテトラグリセリン脂肪酸エステ
ルとしてモノラウリン酸テトラグリセリル、モノオレイ
ン酸テトラグリセリル等、ヘキサグリセリン脂肪酸エス
テルとしてモノミリスチン酸ヘキサグリセリル、ジイソ
ステアリン酸ヘキサグリセリル、セスキイソステアリン
酸ヘキサグリセリル、ジラウリン酸ヘキサグリセリル
等、デカグリセリン脂肪酸エステルとしてモノラウリン
酸デカグリセリル、ジミリスチン酸デカグリセリル、ジ
ステアリン酸デカグリセリル、トリイソステアリン酸デ
カグリセリル、モノオレイン酸デカグリセリル等が挙げ
られる。Specific examples of the tetraglycerin fatty acid ester include tetraglyceryl monolaurate and tetraglyceryl monooleate, and the hexaglycerin fatty acid ester includes hexaglyceryl monomyristate, hexaglyceryl diisostearate, hexaglyceryl sesquiisostearate and hexaglyceryl dilaurate. As the decaglycerin fatty acid ester, decaglyceryl monolaurate, decaglyceryl dimyristate, decaglyceryl distearate, decaglyceryl triisostearate, decaglyceryl monooleate and the like can be mentioned.
【００１５】本発明の組成物は上記必須成分の他に、通
常の皮膚外用剤に用いられる化粧品、医薬部外品、医薬
品等の各種成分、さらに食品に用いられる成分を配合す
ることができる。例えば油性成分、脂質、保湿剤、増粘
剤、薬効成分、殺菌・防腐剤、顔料、粉体、ｐＨ調整
剤、金属イオン封鎖剤、紫外線吸収剤、抗酸化剤、可塑
剤、香料、アミノ酸、甘味料、着色料等を適宜配合する
ことができる。さらにゲル形成能や乳化能を補助する役
割で他の界面活性剤も配合することができる。In addition to the above-mentioned essential components, the composition of the present invention may contain various components such as cosmetics, quasi drugs, pharmaceuticals and the like which are commonly used in external preparations for skin, and components which are used in foods. For example, oily ingredients, lipids, humectants, thickeners, medicinal ingredients, bactericidal / preservatives, pigments, powders, pH adjusters, sequestering agents, ultraviolet absorbers, antioxidants, plasticizers, fragrances, amino acids, Sweeteners, colorants and the like can be appropriately added. Further, other surfactants can be blended in the role of assisting gel forming ability and emulsifying ability.
【００１６】具体的には油性成分としては、例えば油
脂、ロウ類、炭化水素、脂肪酸、高級アルコール、エス
テル、シリコーン油、フッ素油等が挙げられる。保湿剤
としては、例えば多価アルコール、ムコ多糖類、アミノ
酸、糖類、生体高分子等が挙げられる。増粘剤として
は、例えば水溶性高分子、粘土鉱物、高吸水性高分子、
油溶性ゲル化剤等が挙げられる。薬効成分としては、例
えば各種ビタミンおよびその誘導体、アラントイン、グ
リチルリチン酸およびその誘導体、各種動植物抽出物等
が挙げられる。さらに乳化剤としては、例えばポリオキ
シエチレンアルキルエーテル、ポリオキシエチレン脂肪
酸エステル、ポリオキシエチレンソルビタン脂肪酸エス
テル、ソルビタン脂肪酸エステル、グリセリン脂肪酸エ
ステル、ポリオキシエチレン硬化ヒマシ油等の非イオン
界面活性剤、ステアロイル乳酸ナトリウム等のアニオン
界面活性剤、大豆リン脂質等の両性界面活性剤、塩化ア
ルキルトリメチルアンモニウム等のカチオン界面活性剤
が挙げられる。Specific examples of the oily component include fats and oils, waxes, hydrocarbons, fatty acids, higher alcohols, esters, silicone oils, fluorine oils and the like. Examples of the humectant include polyhydric alcohol, mucopolysaccharide, amino acid, saccharide, biopolymer and the like. As the thickener, for example, water-soluble polymer, clay mineral, super absorbent polymer,
Examples thereof include oil-soluble gelling agents. Examples of the medicinal component include various vitamins and their derivatives, allantoin, glycyrrhizic acid and its derivatives, various animal and plant extracts, and the like. Further, as the emulsifier, for example, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, sorbitan fatty acid ester, glycerin fatty acid ester, nonionic surfactant such as polyoxyethylene hydrogenated castor oil, sodium stearoyl lactylate. And the like, amphoteric surfactants such as soybean phospholipids, and cationic surfactants such as alkyltrimethylammonium chloride.
【００１７】本発明のゲル組成物および乳化組成物は公
知の方法により製造することができ化粧品、医薬部外
品、外用医薬品、食品等の分野を問わず利用できるもの
であり、その剤型は目的に応じて任意に選択でき、クリ
ーム、乳液、ローション、ゲル、軟膏、パック、スティ
ック等の形態とすることができる。The gel composition and the emulsified composition of the present invention can be produced by known methods and can be used in any field such as cosmetics, quasi drugs, external medicines, foods, etc. It can be arbitrarily selected according to the purpose and can be in the form of cream, emulsion, lotion, gel, ointment, pack, stick and the like.
【００１８】[0018]
【発明の効果】本発明のゲル組成物および乳化組成物
は、一般式１に示される化合物および／またはその塩と
ポリグリセリン脂肪酸エステルを含有するものであり、
油の乳化能が高く、経時安定性に優れたものである。The gel composition and emulsion composition of the present invention contain the compound represented by the general formula 1 and / or a salt thereof and a polyglycerin fatty acid ester,
The oil has a high emulsifying ability and excellent stability over time.
【００１９】これらの効果を実証するために実施例１〜
１３および比較例１〜８を調製し評価した。In order to demonstrate these effects, Examples 1 to 1
13 and Comparative Examples 1 to 8 were prepared and evaluated.
【００２０】実施例に先立ち、本発明で用いたゲル化方
法、乳化方法、経時安定性の評価方法を説明する。Prior to the examples, a gelling method, an emulsifying method and a method for evaluating stability with time used in the present invention will be described.
【００２１】（ゲル化方法）表１、２に示すＡ部を常温
にて充分攪拌した後、６０℃に加温、同じく６０℃に加
温した油相（Ｂ部）をＡ部に攪拌しながら徐々に加え
る。その後室温まで冷却してゲル組成物を得た。(Gelification method) After thoroughly stirring the parts A shown in Tables 1 and 2 at room temperature, the oil phase (part B) which was heated to 60 ° C. and also heated to 60 ° C. was stirred to the parts A. While gradually adding. Then, it cooled to room temperature and obtained the gel composition.
【００２２】（乳化方法）表１、２に示すＡ部を常温に
て充分攪拌した後、６０℃に加温、同じく６０℃に加温
した油相（Ｂ部）をＡ部に攪拌しながら徐々に加える。
その後７０℃に加温した水相（Ｃ部）を加え撹拌しなが
ら室温まで冷却し乳化組成物を得た。(Emulsification method) After thoroughly stirring the parts A shown in Tables 1 and 2 at room temperature, the oil phase (part B) which was heated to 60 ° C. and also heated to 60 ° C. was stirred to the parts A. Add gradually.
Then, the aqueous phase (part C) heated to 70 ° C. was added, and the mixture was cooled to room temperature with stirring to obtain an emulsified composition.
【００２３】（ゲル組成物の経時安定性の評価）５０℃
にて２週間保存した後の状態を目視にて観察し、以下の
基準に従って経時安定性を評価した。
◎：ゲル化直後と比べ変化がない
○：ゲル化直後と比べ白濁または著しい粘度変化がみら
れる
△：油のしみ出しがみられる
×：ゲルが崩れ明らかな分離がみられる(Evaluation of temporal stability of gel composition) 50 ° C.
The state after storage for 2 weeks was visually observed, and the temporal stability was evaluated according to the following criteria. ◎: No change compared to immediately after gelation ○: White turbidity or remarkable change in viscosity compared to immediately after gelation △: Oil bleeding out ×: Gel collapsed and clear separation is observed
【００２４】（乳化組成物の経時安定性の評価）５０℃
にて２週間保存した後の状態を目視および光学顕微鏡に
て観察し、以下の基準に従って経時安定性を評価した。
◎：外観、乳化粒子ともに、乳化直後と比べ変化がな
く、乳化粒子は２μｍ以下である。
○：外観には変化が見られないが乳化粒子は２μｍ以上
のものがある。
△：分離はみられないが、乳化粒子が大きくなり不均一
である。
×：分離がみられる(Evaluation of temporal stability of emulsion composition) 50 ° C.
After 2 weeks of storage, the state was visually observed and observed with an optical microscope, and the temporal stability was evaluated according to the following criteria. ⊚: Both appearance and emulsified particles are the same as immediately after emulsification, and the emulsified particles are 2 μm or less. ◯: No change in appearance is observed, but some emulsified particles are 2 μm or more. Δ: No separation is observed, but the emulsified particles are large and non-uniform. ×: Separation is observed
【００２５】[0025]
【表１】 [Table 1]
【００２６】表１に示すように、一般式１に示される化
合物（Ｒ１がＬ−ロイシン、Ｒ２が一般式２、Ｒ３がナ
トリウム）（以下、サンプル１とする）とポリグリセリ
ン脂肪酸エステルとしてモノオレイン酸デカグリセリル
を用いた実施例１〜５のゲル組成物の経時安定性は比較
例１〜４に比べ良好な結果であった。As shown in Table 1, the compound represented by the general formula 1 (R 1 is L-leucine, R 2 is the general formula 2, R 3 is sodium) (hereinafter referred to as sample 1) and polyglycerin fatty acid ester The temporal stability of the gel compositions of Examples 1 to 5 using decaglyceryl monooleate as a result was a better result than Comparative Examples 1 to 4.
【００２７】[0027]
【表２】 [Table 2]
【００２８】表２に示すように、サンプル１とポリグリ
セリン脂肪酸エステルとしてモノオレイン酸デカグリセ
リルを用いた実施例６〜１０の乳化組成物の経時安定性
は比較例５〜８に比べ良好な結果であった。As shown in Table 2, the temporal stability of the emulsion compositions of Examples 6 to 10 using sample 1 and decaglyceryl monooleate as the polyglycerin fatty acid ester was better than those of Comparative Examples 5 to 8. Met.
【００２９】以上説明したように、本発明によれば、一
般式１に示される化合物および／またはその塩とポリグ
リセリン脂肪酸エステルを含有することにより、油の乳
化能が高く、経時安定性に優れたゲル組成物および乳化
組成物を提供することが可能となる。As described above, according to the present invention, by containing the compound represented by the general formula 1 and / or its salt and the polyglycerin fatty acid ester, the emulsifying ability of the oil is high and the stability over time is excellent. It is possible to provide a gel composition and an emulsified composition.
【００３０】[0030]
【実施例】以下に本発明を、詳細に説明するため実施例
を挙げるが、本発明はこれらに限定されるものではな
い。EXAMPLES The present invention will now be described with reference to examples, but the present invention is not limited thereto.
【００３１】 実施例１１ 保湿ゲルクリーム Ａ サンプル１ ２．０重量％ ジイソステアリン酸ヘキサグリセリル １．０ グリセリン ５．０ Ｂ スクワラン ４０．０ ミリスチン酸オクチルドデシル ５０．０ ステアリルアルコール ２．０ セタノール １．０ ビタミンＥアセテート 適量 香料 適量[0031] Example 11 Moisturizing gel cream A sample 1 2.0% by weight Hexaglyceryl diisostearate 1.0 Glycerin 5.0 B Squalane 40.0 Octyldodecyl myristate 50.0 Stearyl alcohol 2.0 Cetanol 1.0 Vitamin E acetate moderate amount Fragrance suitable amount
【００３２】Ａ部およびＢ部を６０℃に加温した後、Ｂ
部をＡ部に攪拌しながら徐々に加えてゲル組成物を得
る。その後室温まで冷却する。得られたゲル組成物は経
時安定性に優れた良好な保湿ゲルクリームであった。After heating the parts A and B to 60 ° C.,
Parts are gradually added to part A with stirring to obtain a gel composition. Then cool to room temperature. The obtained gel composition was a good moisturizing gel cream excellent in stability over time.
【００３３】 実施例１２ クレンジングジェル Ａ サンプル２ ５．０重量％ （一般式１のＲ１はＬ−バリン、 Ｒ２はＣ１４〜１６の飽和分岐のアルキル、Ｒ３は水素） モノオレイン酸デカグリセリル １．５ グリセリン ５．０ Ｂ 流動パラフィン ５０．０ イソノナン酸イソノニル ２０．０ ナイロン粉末 １．０ 香料 適量 Ｃ １，３−ブチレングリコール ５．０ カルボキシビニルポリマー １．０ 水酸化ナトリウム ０．５ キサンタンガム ０．２ 防腐剤 適量 精製水 残余[0033] Example 12 Cleansing Gel A sample 2 5.0 wt% (R 1 of Formula 1 is L- valine, R 2 is alkyl of saturated branched C 14 ~ 16, R 3 is hydrogen) monooleate deca Glyceryl 1.5 Glycerin 5.0 B Liquid paraffin 50.0 Isononyl isononanoate 20.0 Nylon powder 1.0 Perfume Suitable amount C 1,3-butylene glycol 5.0 Carboxyvinyl polymer 1.0 Sodium hydroxide 0.5 Xanthan gum 0.2 Preservative Suitable amount Purified water Residual
【００３４】Ａ部およびＢ部を６０℃に加温した後、Ｂ
部をＡ部に攪拌しながら徐々に加えてゲル組成物を得
る。その後７０℃に加温したＣ部を加え攪拌しながら乳
化し、室温まで冷却する。得られたクレンジングは粒子
径２μｍ以下の良好な乳化組成物であり、経時安定性は
良好であった。また、使用感はさっぱりし、べたつきの
無いものであった。After heating parts A and B to 60 ° C.,
Parts are gradually added to part A with stirring to obtain a gel composition. After that, part C heated to 70 ° C. is added and the mixture is emulsified with stirring and cooled to room temperature. The resulting cleansing composition was a good emulsion composition having a particle size of 2 μm or less, and had good stability over time. Also, the feeling of use was refreshing and there was no stickiness.
【００３５】 実施例１３ 懸濁タイプ化粧水 Ａ サンプル３ １．０重量％ （一般式１のＲ１はＬ−ロイシン、 Ｒ２はＣ１８の分岐アルキル、Ｒ３はカリウム） モノラウリン酸テトラグリセリル ０．３ セスキイソステアリン酸ヘキサグリセリル ０．３ グリセリン １．０ Ｂ ヒマワリ油 ５．０ ホホバ油 ５．０ ビタミンＡパルミテート ０．１ 香料 適量 Ｃ 防腐剤 適量 金属イオン封鎖剤 適量 ｐＨ調整剤 適量 精製水 残余Example 13 Suspension type lotion A Sample 3 1.0% by weight (R 1 of the general formula 1 is L-leucine, R 2 is a C 18 branched alkyl, R 3 is potassium) Tetraglyceryl monolaurate 0 .3 Hexaglyceryl sesquiisostearate 0.3 Glycerin 1.0 B Sunflower oil 5.0 Jojoba oil 5.0 Vitamin A palmitate 0.1 Fragrance suitable amount C preservative suitable amount sequestering agent appropriate amount pH adjuster appropriate amount purified water residual
【００３６】Ａ部およびＢ部を６０℃に加温した後、Ｂ
部をＡ部に攪拌しながら徐々に加えてゲル組成物を得
る。その後７０℃に加温したＣ部を加え攪拌しながら乳
化し、室温まで冷却する。得られた懸濁タイプ化粧水は
粒子径２μｍ以下の良好な乳化組成物であり、経時安定
性は良好であった。また、使用感はさっぱりし、べたつ
きの無いものであった。After heating the parts A and B to 60 ° C.,
Parts are gradually added to part A with stirring to obtain a gel composition. After that, part C heated to 70 ° C. is added and the mixture is emulsified with stirring and cooled to room temperature. The obtained suspension-type lotion was a good emulsion composition having a particle size of 2 μm or less, and had good stability over time. Also, the feeling of use was refreshing and there was no stickiness.
───────────────────────────────────────────────────── フロントページの続き (72)発明者 北原 路郎 愛知県名古屋市西区鳥見町２−７ 日本メ ナード化粧品株式会社総合研究所 (72)発明者 中田 悟 愛知県名古屋市西区鳥見町２−７ 日本メ ナード化粧品株式会社総合研究所 Ｆターム(参考） 4C083 AA122 AB032 AC022 AC072 AC122 AC342 AC352 AC421 AC422 AD072 AD092 AD152 AD352 AD411 AD412 AD622 AD662 BB51 CC04 CC05 CC22 DD22 DD27 DD31 DD41 EE01 EE06 EE12 4G065 AA01 AB02Y AB05Y AB11Y AB12Y AB18Y AB38Y BB06 BB08 CA02 CA14 DA02 EA02 ─────────────────────────────────────────────────── ─── Continued front page (72) Inventor Jiro Kitahara 2-7 Torimicho, Nishi-ku, Nagoya-shi, Aichi Japan Nard Cosmetics Co., Ltd. (72) Inventor Satoru Nakata 2-7 Torimicho, Nishi-ku, Nagoya-shi, Aichi Japan Nard Cosmetics Co., Ltd. F term (reference) 4C083 AA122 AB032 AC022 AC072 AC122 AC342 AC352 AC421 AC422 AD072 AD092 AD152 AD352 AD411 AD412 AD622 AD662 BB51 CC04 CC05 CC22 DD22 DD27 DD31 DD41 EE01 EE06 EE12 4G065 AA01 AB02Y AB05Y AB11Y AB12Y AB18Y AB38Y BB06 BB08 CA02 CA14 DA02 EA02
Claims (8)
ル、Ｒ３は水素）に示される化合物および／またはその
塩とポリグリセリン脂肪酸エステルを含有することを特
徴とするゲル組成物。 【化１】 1. A gel composition comprising a compound represented by the general formula 1 (R 1 is an amino acid, R 2 is alkyl, R 3 is hydrogen) and / or a salt thereof and a polyglycerin fatty acid ester. [Chemical 1]
ロイシン、Ｌ−バリンから選ばれるアミノ酸であり、Ｒ
２はＣ８〜Ｃ２２のアルキルであり、Ｒ３は水素または
アルカリ金属であることを特徴とする請求項１に記載の
ゲル組成物。2. R 1 in the general formula 1 is an amino acid selected from L-leucine, L-isoleucine and L-valine, and R 1
The gel composition according to claim 1, wherein 2 is C 8 to C 22 alkyl, and R 3 is hydrogen or an alkali metal.
般式２、Ｒ３はナトリウムであることを特徴とする請求
項１乃至請求項２に記載のゲル組成物。 【化２】 3. The gel composition according to claim 1, wherein R 1 in the general formula 1 is L-leucine, R 2 is the general formula 2, and R 3 is sodium. [Chemical 2]
セリン部は平均重合度が４以上であり、脂肪酸部はＣ８
〜Ｃ２２であることを特徴とする請求項１乃至請求項３
に記載のゲル組成物。4. The polyglycerin part of the polyglycerin fatty acid ester has an average degree of polymerization of 4 or more, and the fatty acid part is C 8
Claim characterized in that it is a -C 22 1 through claim 3
The gel composition according to 1.
その塩とポリグリセリン脂肪酸エステルとグリセリンを
混合し、撹拌しながら油相を徐々に加え、請求項１乃至
請求項４に記載のゲル組成物を得ることを特徴とするゲ
ル化法。5. The gel composition according to claim 1, wherein the compound represented by the general formula 1 and / or its salt, polyglycerin fatty acid ester and glycerin are mixed and the oil phase is gradually added while stirring. A gelling method characterized by obtaining a product.
その塩の含有量が０．１〜１０重量％であり、ポリグリ
セリン脂肪酸エステルの含有量が０．１〜５重量％であ
ることを特徴とする請求項１乃至請求項５に記載のゲル
組成物。6. The content of the compound represented by the general formula 1 and / or its salt is 0.1 to 10% by weight, and the content of polyglycerin fatty acid ester is 0.1 to 5% by weight. The gel composition according to any one of claims 1 to 5, which is characterized.
組成物に、水を添加して乳化した乳化組成物。7. An emulsified composition obtained by adding water to the gel composition according to claim 1 to emulsify it.
る請求項１乃至請求項７に記載のゲル組成物および／ま
たは乳化組成物。8. The gel composition and / or the emulsified composition according to claim 1, which is used as a skin external preparation.
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| JP2002013761A JP3799276B2 (en) | 2002-01-23 | 2002-01-23 | Gel composition and emulsion composition |
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| JP2003212750A true JP2003212750A (en) | 2003-07-30 |
| JP3799276B2 JP3799276B2 (en) | 2006-07-19 |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012165145A1 (en) * | 2011-06-01 | 2012-12-06 | 株式会社ダイセル | Oily gel composition |
| JP2016094397A (en) * | 2014-11-11 | 2016-05-26 | 東洋紡株式会社 | Emulsion composition |
| JP2016094398A (en) * | 2014-11-11 | 2016-05-26 | 東洋紡株式会社 | Emulsion composition |
| JP2016094396A (en) * | 2014-11-11 | 2016-05-26 | 東洋紡株式会社 | Emulsion composition |
| WO2017209241A1 (en) * | 2016-06-01 | 2017-12-07 | 株式会社カネカ | Emulsified composition and cosmetic using same |
| JP2018177851A (en) * | 2017-04-04 | 2018-11-15 | 日華化学株式会社 | Scouring agent composition and method for producing fiber product |
| WO2019138739A1 (en) * | 2018-01-12 | 2019-07-18 | 株式会社カネカ | Gel-state composition and production method therefor |
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2002
- 2002-01-23 JP JP2002013761A patent/JP3799276B2/en not_active Expired - Lifetime
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012165145A1 (en) * | 2011-06-01 | 2012-12-06 | 株式会社ダイセル | Oily gel composition |
| JP2016094397A (en) * | 2014-11-11 | 2016-05-26 | 東洋紡株式会社 | Emulsion composition |
| JP2016094398A (en) * | 2014-11-11 | 2016-05-26 | 東洋紡株式会社 | Emulsion composition |
| JP2016094396A (en) * | 2014-11-11 | 2016-05-26 | 東洋紡株式会社 | Emulsion composition |
| WO2017209241A1 (en) * | 2016-06-01 | 2017-12-07 | 株式会社カネカ | Emulsified composition and cosmetic using same |
| JP2018177851A (en) * | 2017-04-04 | 2018-11-15 | 日華化学株式会社 | Scouring agent composition and method for producing fiber product |
| WO2019138739A1 (en) * | 2018-01-12 | 2019-07-18 | 株式会社カネカ | Gel-state composition and production method therefor |
| CN111565702A (en) * | 2018-01-12 | 2020-08-21 | 株式会社钟化 | Gel composition and method for producing same |
| JPWO2019138739A1 (en) * | 2018-01-12 | 2020-12-24 | 株式会社カネカ | Gel-like composition and method for producing the same |
| JP7212634B2 (en) | 2018-01-12 | 2023-01-25 | 株式会社カネカ | GEL COMPOSITION AND METHOD FOR MANUFACTURING SAME |
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