JP2003146888A5 - - Google Patents
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- JP2003146888A5 JP2003146888A5 JP2001348744A JP2001348744A JP2003146888A5 JP 2003146888 A5 JP2003146888 A5 JP 2003146888A5 JP 2001348744 A JP2001348744 A JP 2001348744A JP 2001348744 A JP2001348744 A JP 2001348744A JP 2003146888 A5 JP2003146888 A5 JP 2003146888A5
- Authority
- JP
- Japan
- Prior art keywords
- epithelial cells
- intestinal epithelial
- thought
- lps
- intestinal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Description
従って、LPSシグナルは、炎症性腸疾患の発症・悪化において重要な要素である。LPSのような細菌成分は腸表面に直接影響し、腸上皮細胞における免疫反応を誘発すると考えられる。即ち、LPSシグナルは腸上皮細胞におけるIL-6の産生を引き起こし、大腸炎を発生させると思われる。従って、腸上皮細胞からのこれらシグナルの除去が腸炎の改善に寄与する可能性は高い。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001348744A JP4169966B2 (ja) | 2001-11-14 | 2001-11-14 | 炎症性腸疾患予防治療剤 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001348744A JP4169966B2 (ja) | 2001-11-14 | 2001-11-14 | 炎症性腸疾患予防治療剤 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2003146888A JP2003146888A (ja) | 2003-05-21 |
JP2003146888A5 true JP2003146888A5 (ja) | 2005-05-19 |
JP4169966B2 JP4169966B2 (ja) | 2008-10-22 |
Family
ID=19161521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001348744A Expired - Fee Related JP4169966B2 (ja) | 2001-11-14 | 2001-11-14 | 炎症性腸疾患予防治療剤 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP4169966B2 (ja) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1917899B (zh) | 2004-02-04 | 2013-04-17 | 塞浦西斯阿瓦药物集团 | 碱性磷酸酶对存在于粘膜屏障的脂多糖解毒的用途 |
PL1965809T3 (pl) | 2005-11-21 | 2010-02-26 | Bioatlantis Ltd | Kompozycje do poprawiania zdrowia jelit i użytkowości zwierząt zawierające beta-glukany i alfa-fukany |
JP5022060B2 (ja) * | 2007-02-28 | 2012-09-12 | 森永乳業株式会社 | インターロイキン−10産生促進剤 |
JP2010018605A (ja) * | 2008-06-10 | 2010-01-28 | Kaisanbutsuno Kimuraya:Kk | 腸内環境改善剤 |
PL2432478T3 (pl) | 2009-05-21 | 2022-01-17 | Bioatlantis Ltd | Poprawa stanu, odporności i wydajności przewodu pokarmowego poprzez interwencję żywieniową |
CN101991598A (zh) * | 2010-12-06 | 2011-03-30 | 吉林省辉南长龙生化药业股份有限公司 | 褐藻多糖硫酸酯在制备治疗胃肠疾病药物中的用途 |
CN112029753A (zh) | 2014-01-24 | 2020-12-04 | 安-法玛公司 | 碱性磷酸酶的下游处理 |
WO2015112017A1 (en) | 2014-01-24 | 2015-07-30 | Am-Pharma B.V. | Chimeric alkaline phosphatase-like proteins |
CN104721572B (zh) * | 2015-04-16 | 2018-11-23 | 郑于静 | 一种治疗慢性结肠炎的中药 |
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2001
- 2001-11-14 JP JP2001348744A patent/JP4169966B2/ja not_active Expired - Fee Related
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