JP2001509369A - ガン細胞を特異的に検出する4b5と命名される抗原結合フラグメント、フラグメントをコードするヌクレオチド、ならびにガンの予防および検出のためのそれらの使用 - Google Patents

ガン細胞を特異的に検出する4b5と命名される抗原結合フラグメント、フラグメントをコードするヌクレオチド、ならびにガンの予防および検出のためのそれらの使用

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Publication number
JP2001509369A
JP2001509369A JP2000502064A JP2000502064A JP2001509369A JP 2001509369 A JP2001509369 A JP 2001509369A JP 2000502064 A JP2000502064 A JP 2000502064A JP 2000502064 A JP2000502064 A JP 2000502064A JP 2001509369 A JP2001509369 A JP 2001509369A
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JP
Japan
Prior art keywords
polynucleotide
composition
antibody
cells
polypeptide
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000502064A
Other languages
English (en)
Japanese (ja)
Inventor
マイケル ディー. ダン,
マンソール サレー,
マーク ナソフ,
Original Assignee
ノボファーム バイオテック インコーポレイテッド
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Application filed by ノボファーム バイオテック インコーポレイテッド filed Critical ノボファーム バイオテック インコーポレイテッド
Publication of JP2001509369A publication Critical patent/JP2001509369A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • C07K16/4266Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2000502064A 1997-07-08 1998-07-08 ガン細胞を特異的に検出する4b5と命名される抗原結合フラグメント、フラグメントをコードするヌクレオチド、ならびにガンの予防および検出のためのそれらの使用 Withdrawn JP2001509369A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5194597P 1997-07-08 1997-07-08
US60/051,945 1997-07-08
PCT/IB1998/001046 WO1999002545A2 (fr) 1997-07-08 1998-07-08 Fragments de liaison antigeniques designes par 4b5, qui detectent specifiquement les cellules cancereuses, nucleotides codant lesdits fragments et leur utilisation pour la prophylaxie et la detection des cancers

Publications (1)

Publication Number Publication Date
JP2001509369A true JP2001509369A (ja) 2001-07-24

Family

ID=21974384

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000502064A Withdrawn JP2001509369A (ja) 1997-07-08 1998-07-08 ガン細胞を特異的に検出する4b5と命名される抗原結合フラグメント、フラグメントをコードするヌクレオチド、ならびにガンの予防および検出のためのそれらの使用

Country Status (6)

Country Link
EP (1) EP1000082A2 (fr)
JP (1) JP2001509369A (fr)
AU (1) AU7927398A (fr)
CA (1) CA2295375A1 (fr)
NZ (1) NZ501990A (fr)
WO (1) WO1999002545A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010510504A (ja) * 2006-11-21 2010-04-02 エフ.ホフマン−ラ ロシュ アーゲー 免疫測定法における標準としての抗イディオタイプ結合体およびその使用

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE309360T1 (de) 1994-03-08 2005-11-15 Human Genome Sciences Inc Vaskularer endothelialer wachstumsfaktor 2
US7153827B1 (en) 1994-03-08 2006-12-26 Human Genome Sciences, Inc. Vascular endothelial growth factor 2 and methods of use
US7186688B1 (en) 1994-03-08 2007-03-06 Human Genome Sciences, Inc. Methods of stimulating angiogenesis in a patient by administering vascular endothelial growth factor 2
US6040157A (en) 1994-03-08 2000-03-21 Human Genome Sciences, Inc. Vascular endothelial growth factor 2
US7109308B1 (en) 1994-03-08 2006-09-19 Human Genome Sciences, Inc. Antibodies to human vascular endothelial growth factor 2
US5932540A (en) 1994-03-08 1999-08-03 Human Genome Sciences, Inc. Vascular endothelial growth factor 2
US6608182B1 (en) 1994-03-08 2003-08-19 Human Genome Sciences, Inc. Human vascular endothelial growth factor 2
US7223724B1 (en) 1999-02-08 2007-05-29 Human Genome Sciences, Inc. Use of vascular endothelial growth factor to treat photoreceptor cells
JP2003527116A (ja) * 2000-03-15 2003-09-16 インサイト・ゲノミックス・インコーポレイテッド ヒト免疫応答タンパク質
NZ518077A (en) 2000-08-04 2003-11-28 Human Genome Sciences Inc Biologically active fragments, analogues and derivatives of VEGF-2 for the treatment of peripheral artery diseases such as critical limb ischemia and coronary disease
DE10059930A1 (de) * 2000-11-23 2002-05-29 Fischer Peter Mittel humanen Ursprungs zur Vakzination gegen GD2-pos. Tumore
WO2002083704A1 (fr) 2001-04-13 2002-10-24 Human Genome Sciences, Inc. Facteur de croissance 2, endothelial, vasculaire
US7402312B2 (en) 2001-04-13 2008-07-22 Human Genome Sciences, Inc. Antibodies to vascular endothelial growth factor 2 (VEGF-2)
EP1380290A1 (fr) * 2002-07-09 2004-01-14 Universitair Medisch Centrum Utrecht La voie de la structure cross-béta et sa pertinence thérapeutique
US7473424B2 (en) * 2003-01-31 2009-01-06 The Scripps Research Institute Anti-dengue virus antibodies and compositions
WO2015095002A1 (fr) * 2013-12-16 2015-06-25 Texas Tech University System Anticorps monoclonaux anti-ron en tant que système d'administration de médicaments cytotoxiques pour une thérapie anticancéreuse ciblée

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5653977A (en) * 1993-09-09 1997-08-05 Uab Research Foundation Anti-idiotypic antibody that mimics the GD2 antigen
DK0796280T3 (da) * 1994-12-28 2003-04-22 Univ Kentucky Murint monoklonalt anti-idiotypisk antistof 3H1
US5612030A (en) * 1995-01-17 1997-03-18 University Of Kentucky Research Foundation Anti-idiotype monoclonal antibody 1A7 and use for the treatment of melanoma and small cell carcinoma

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010510504A (ja) * 2006-11-21 2010-04-02 エフ.ホフマン−ラ ロシュ アーゲー 免疫測定法における標準としての抗イディオタイプ結合体およびその使用

Also Published As

Publication number Publication date
WO1999002545A2 (fr) 1999-01-21
EP1000082A2 (fr) 2000-05-17
WO1999002545A3 (fr) 1999-04-01
NZ501990A (en) 2002-09-27
CA2295375A1 (fr) 1999-01-21
AU7927398A (en) 1999-02-08

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Effective date: 20051004