JOP20210047A1 - عامل وقائي و/أو علاجي للأعراض السلوكية والنفسية المصحوبة بمرض تنكسي عصبي أو الأعراض الإندفاعية المصحوبة بمرض ذهني، يحتوي على بريكسبيرازول أو ملحه - Google Patents
عامل وقائي و/أو علاجي للأعراض السلوكية والنفسية المصحوبة بمرض تنكسي عصبي أو الأعراض الإندفاعية المصحوبة بمرض ذهني، يحتوي على بريكسبيرازول أو ملحهInfo
- Publication number
- JOP20210047A1 JOP20210047A1 JOP/2021/0047A JOP20210047A JOP20210047A1 JO P20210047 A1 JOP20210047 A1 JO P20210047A1 JO P20210047 A JOP20210047 A JO P20210047A JO P20210047 A1 JOP20210047 A1 JO P20210047A1
- Authority
- JO
- Jordan
- Prior art keywords
- symptoms associated
- behavioral
- prophylactic
- salt
- therapeutic agent
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Abstract
يتعلق هذا الاختراع بعامل وقائي و/أو علاجي للأعراض السلوكية والنفسية المصاحبة لمرض تنكسي عصبي أو الأعراض الاندفاعية المصاحبة للمرض العقلي، والذي يحتوي على المركب 7 - [4 - (4-بنزو [ب] –ثيوفين-4-يل-بيبرازين-1-يل)بوتوكسي]-1 اتش- كينولين-2-ون أو ملحه كمركب فعال او كعنصر فعال.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261718305P | 2012-10-25 | 2012-10-25 | |
US201361782467P | 2013-03-14 | 2013-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
JOP20210047A1 true JOP20210047A1 (ar) | 2017-06-16 |
Family
ID=49585556
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2021/0047A JOP20210047A1 (ar) | 2012-10-25 | 2012-10-25 | عامل وقائي و/أو علاجي للأعراض السلوكية والنفسية المصحوبة بمرض تنكسي عصبي أو الأعراض الإندفاعية المصحوبة بمرض ذهني، يحتوي على بريكسبيرازول أو ملحه |
JOP/2013/0313A JOP20130313B1 (ar) | 2012-10-25 | 2013-10-24 | عامل وقائي و/أو علاجي للأعراض السلوكية والنفسية المصحوبة بمرض تنكسي عصبي أو الأعراض الإندفاعية المصحوبة بمرض ذهني، يحتوي على بريكسبيرازول أو ملحه |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2013/0313A JOP20130313B1 (ar) | 2012-10-25 | 2013-10-24 | عامل وقائي و/أو علاجي للأعراض السلوكية والنفسية المصحوبة بمرض تنكسي عصبي أو الأعراض الإندفاعية المصحوبة بمرض ذهني، يحتوي على بريكسبيرازول أو ملحه |
Country Status (22)
Country | Link |
---|---|
US (4) | US20150272946A1 (ar) |
EP (2) | EP2911670A1 (ar) |
JP (5) | JP6329140B2 (ar) |
KR (1) | KR102245016B1 (ar) |
CN (4) | CN108578408A (ar) |
AR (1) | AR093247A1 (ar) |
AU (1) | AU2013335613B2 (ar) |
BR (1) | BR112015008759A2 (ar) |
CA (1) | CA2889196C (ar) |
EA (1) | EA201590808A1 (ar) |
HK (1) | HK1212609A1 (ar) |
IL (1) | IL238402B (ar) |
JO (2) | JOP20210047A1 (ar) |
MX (1) | MX371279B (ar) |
MY (1) | MY180185A (ar) |
NZ (1) | NZ708321A (ar) |
PH (1) | PH12015500925A1 (ar) |
SG (2) | SG10201702828TA (ar) |
TW (1) | TWI643620B (ar) |
UA (1) | UA116549C2 (ar) |
WO (1) | WO2014065437A1 (ar) |
ZA (1) | ZA201503640B (ar) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200523253A (en) | 2003-07-22 | 2005-07-16 | Arena Pharm Inc | Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related thereto |
TWI415845B (zh) | 2006-10-03 | 2013-11-21 | Arena Pharm Inc | 用於治療與5-ht2a血清素受體相關聯病症之作為5-ht2a血清素受體之調節劑的吡唑衍生物 |
JP5393677B2 (ja) | 2007-08-15 | 2014-01-22 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 5−HT2Aセロトニン受容体に関連した障害の治療のための5−HT2Aセロトニン受容体のモジュレーターとしてのイミダゾ[1,2−a]ピリジン誘導体 |
US20110021538A1 (en) | 2008-04-02 | 2011-01-27 | Arena Pharmaceuticals, Inc. | Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor |
WO2010062323A2 (en) | 2008-10-28 | 2010-06-03 | Arena Pharmaceuticals, Inc. | Compositions of a 5-ht2a serotonin receptor modulator useful for the treatment of disorders related thereto |
US9126946B2 (en) | 2008-10-28 | 2015-09-08 | Arena Pharmaceuticals, Inc. | Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto |
SG11201608766TA (en) * | 2014-04-22 | 2016-11-29 | Otsuka Pharma Co Ltd | Combination of brexpiprazole and nalmefene and use thereof for treating substance-related disorders |
WO2016115144A1 (en) * | 2015-01-12 | 2016-07-21 | Reviva Pharmaceuticals Inc. | Methods for treating alzheimer's disease |
WO2016115150A1 (en) * | 2015-01-12 | 2016-07-21 | Reviva Pharmaceuticals Inc. | Methods for treating psychosis associated with parkinson's disease |
MX2017016413A (es) | 2015-06-12 | 2018-08-01 | Axovant Sciences Gmbh | Derivados de diaril y arilheteroaril urea como moduladores del receptor 5ht2a de serotonina útiles para la profilaxis y el tratamineto de un trastorno conductual del sueño rem. |
CA2992518A1 (en) | 2015-07-15 | 2017-01-19 | Axovant Sciences Gmbh | Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease |
CN105175401A (zh) * | 2015-10-16 | 2015-12-23 | 北京康立生医药技术开发有限公司 | 一种依匹哌唑的制备方法 |
CN105541819B (zh) * | 2016-02-04 | 2018-09-14 | 浙江永宁药业股份有限公司 | 一种依匹唑派的制备方法及其中间体和中间体的制备方法 |
CN115813887A (zh) | 2016-12-20 | 2023-03-21 | 罗曼治疗***股份公司 | 包含阿塞那平的透皮治疗*** |
US11337932B2 (en) | 2016-12-20 | 2022-05-24 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene |
CA3067938A1 (en) | 2017-06-26 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine and silicone acrylic hybrid polymer |
EP3720435B1 (en) | 2017-12-05 | 2024-03-06 | Sunovion Pharmaceuticals Inc. | Crystal forms and production methods thereof |
BR112020011189A2 (pt) | 2017-12-05 | 2020-11-17 | Sunovion Pharmaceuticals Inc. | misturas não racêmicas e usos das mesmas |
EP3501506B1 (en) | 2017-12-19 | 2019-10-09 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Pharmaceutical tablet composition comprising brexpiprazole |
KR20210022656A (ko) | 2018-06-20 | 2021-03-03 | 에르테에스 로만 테라피-시스테메 아게 | 아세나핀을 함유하는 경피 치료 시스템 |
JP2022535893A (ja) | 2019-06-04 | 2022-08-10 | サノビオン ファーマシューティカルズ インク | 放出調節製剤およびその使用 |
JPWO2021029020A1 (ar) * | 2019-08-13 | 2021-02-18 | ||
WO2021261571A1 (ja) * | 2020-06-24 | 2021-12-30 | 国立大学法人北海道大学 | 血液脳脊髄関門保護剤 |
CN112137994B (zh) * | 2020-09-15 | 2022-10-14 | 中山大学 | 小分子化合物在制备抗丝状病毒药物中的应用 |
US11229644B1 (en) * | 2020-12-31 | 2022-01-25 | Lake O'hara Llc | Methods of treating psychiatric disorders in obese patients with brexpiprazole |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4315393B2 (ja) * | 2005-04-14 | 2009-08-19 | 大塚製薬株式会社 | 複素環化合物 |
TWI320783B (en) * | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
JP4540700B2 (ja) * | 2006-10-13 | 2010-09-08 | 大塚製薬株式会社 | 医薬 |
JP2011136906A (ja) * | 2008-04-18 | 2011-07-14 | Otsuka Pharmaceut Co Ltd | 複素環化合物 |
JOP20120083B1 (ar) * | 2011-04-05 | 2021-08-17 | Otsuka Pharma Co Ltd | توليفات تشتمل على بريكس ببرازول أو ملح منه وعقار ثاني للاستخدام في علاج اضطراب cns |
AR090775A1 (es) * | 2012-04-23 | 2014-12-03 | Otsuka Pharma Co Ltd | Preparado inyectable |
TWI562991B (en) * | 2012-04-23 | 2016-12-21 | Otsuka Pharma Co Ltd | Dihydrate of benzothiophene compound or of a salt thereof, and process for producing the same |
EP2822136B1 (en) * | 2013-07-03 | 2018-08-29 | Siemens Aktiengesellschaft | Method and arrangement for transferring electrical power for subsea applications |
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2012
- 2012-10-25 JO JOP/2021/0047A patent/JOP20210047A1/ar unknown
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2013
- 2013-10-24 CN CN201810366157.4A patent/CN108578408A/zh active Pending
- 2013-10-24 NZ NZ708321A patent/NZ708321A/en unknown
- 2013-10-24 WO PCT/JP2013/079480 patent/WO2014065437A1/en active Application Filing
- 2013-10-24 TW TW102138482A patent/TWI643620B/zh active
- 2013-10-24 CA CA2889196A patent/CA2889196C/en active Active
- 2013-10-24 EA EA201590808A patent/EA201590808A1/ru unknown
- 2013-10-24 AU AU2013335613A patent/AU2013335613B2/en active Active
- 2013-10-24 KR KR1020157013570A patent/KR102245016B1/ko active IP Right Grant
- 2013-10-24 UA UAA201505106A patent/UA116549C2/uk unknown
- 2013-10-24 SG SG10201702828TA patent/SG10201702828TA/en unknown
- 2013-10-24 EP EP13792110.2A patent/EP2911670A1/en not_active Withdrawn
- 2013-10-24 CN CN202210498926.2A patent/CN114712360A/zh active Pending
- 2013-10-24 SG SG11201503152TA patent/SG11201503152TA/en unknown
- 2013-10-24 JO JOP/2013/0313A patent/JOP20130313B1/ar active
- 2013-10-24 BR BR112015008759A patent/BR112015008759A2/pt not_active Application Discontinuation
- 2013-10-24 CN CN201380055961.6A patent/CN104755082A/zh active Pending
- 2013-10-24 MY MYPI2015701327A patent/MY180185A/en unknown
- 2013-10-24 JP JP2015521734A patent/JP6329140B2/ja active Active
- 2013-10-24 MX MX2015005174A patent/MX371279B/es active IP Right Grant
- 2013-10-24 CN CN202011339120.6A patent/CN112402421A/zh active Pending
- 2013-10-24 AR ARP130103867A patent/AR093247A1/es unknown
- 2013-10-24 EP EP21159914.7A patent/EP3848033A1/en active Pending
- 2013-10-24 US US14/438,335 patent/US20150272946A1/en not_active Abandoned
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2015
- 2015-04-21 IL IL238402A patent/IL238402B/en active IP Right Grant
- 2015-04-24 PH PH12015500925A patent/PH12015500925A1/en unknown
- 2015-05-22 ZA ZA2015/03640A patent/ZA201503640B/en unknown
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2016
- 2016-01-19 HK HK16100569.3A patent/HK1212609A1/zh unknown
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2017
- 2017-03-28 US US15/471,429 patent/US20170258787A1/en not_active Abandoned
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2018
- 2018-03-29 JP JP2018065319A patent/JP2018138555A/ja active Pending
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2019
- 2019-06-28 US US16/456,334 patent/US20190314367A1/en not_active Abandoned
- 2019-10-29 JP JP2019195831A patent/JP2020045345A/ja active Pending
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2021
- 2021-07-19 JP JP2021118416A patent/JP2021181448A/ja active Pending
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2022
- 2022-07-21 US US17/869,993 patent/US20220370442A1/en active Pending
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2023
- 2023-05-30 JP JP2023088455A patent/JP2023123441A/ja active Pending
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