ITUB20161079A1 - Procedimento per la preparazione di sofosbuvir - Google Patents

Procedimento per la preparazione di sofosbuvir

Info

Publication number
ITUB20161079A1
ITUB20161079A1 ITUB2016A001079A ITUB20161079A ITUB20161079A1 IT UB20161079 A1 ITUB20161079 A1 IT UB20161079A1 IT UB2016A001079 A ITUB2016A001079 A IT UB2016A001079A IT UB20161079 A ITUB20161079 A IT UB20161079A IT UB20161079 A1 ITUB20161079 A1 IT UB20161079A1
Authority
IT
Italy
Prior art keywords
sofosbuvir
procedure
preparation
Prior art date
Application number
ITUB2016A001079A
Other languages
English (en)
Inventor
Mauro Gaboardi
Giuseppe Pallanza
Marco Baratella
Graziano Castaldi
Marta Castaldi
Original Assignee
Hc Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hc Pharma Ag filed Critical Hc Pharma Ag
Priority to ITUB2016A001079A priority Critical patent/ITUB20161079A1/it
Priority to US15/358,850 priority patent/US10112967B2/en
Priority to EP17705157.0A priority patent/EP3419983B1/en
Priority to ES17705157T priority patent/ES2936819T3/es
Priority to PCT/EP2017/053815 priority patent/WO2017144423A1/en
Priority to ARP170100460A priority patent/AR107712A1/es
Publication of ITUB20161079A1 publication Critical patent/ITUB20161079A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/305Pyrimidine nucleotides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
ITUB2016A001079A 2016-02-25 2016-02-25 Procedimento per la preparazione di sofosbuvir ITUB20161079A1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ITUB2016A001079A ITUB20161079A1 (it) 2016-02-25 2016-02-25 Procedimento per la preparazione di sofosbuvir
US15/358,850 US10112967B2 (en) 2016-02-25 2016-11-22 Process for the preparation of sofosbuvir
EP17705157.0A EP3419983B1 (en) 2016-02-25 2017-02-20 Process for the preparation of sofosbuvir
ES17705157T ES2936819T3 (es) 2016-02-25 2017-02-20 Procedimiento de preparación de sofosbuvir
PCT/EP2017/053815 WO2017144423A1 (en) 2016-02-25 2017-02-20 Process for the preparation of sofosbuvir
ARP170100460A AR107712A1 (es) 2016-02-25 2017-02-23 Proceso para preparar sofosbuvir

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUB2016A001079A ITUB20161079A1 (it) 2016-02-25 2016-02-25 Procedimento per la preparazione di sofosbuvir

Publications (1)

Publication Number Publication Date
ITUB20161079A1 true ITUB20161079A1 (it) 2017-08-25

Family

ID=56134469

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUB2016A001079A ITUB20161079A1 (it) 2016-02-25 2016-02-25 Procedimento per la preparazione di sofosbuvir

Country Status (6)

Country Link
US (1) US10112967B2 (it)
EP (1) EP3419983B1 (it)
AR (1) AR107712A1 (it)
ES (1) ES2936819T3 (it)
IT (1) ITUB20161079A1 (it)
WO (1) WO2017144423A1 (it)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7964580B2 (en) 2007-03-30 2011-06-21 Pharmasset, Inc. Nucleoside phosphoramidate prodrugs
WO2015017713A1 (en) 2013-08-01 2015-02-05 Idenix Pharmaceuticals, Inc. D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
US10449210B2 (en) 2014-02-13 2019-10-22 Ligand Pharmaceuticals Inc. Prodrug compounds and their uses
WO2015123353A1 (en) 2014-02-14 2015-08-20 Kci Licensing, Inc. Systems and methods for increasing absorbent capacity of a dressing
CN104327138B (zh) 2014-10-21 2017-05-10 齐鲁制药有限公司 Psi‑7977中间体化合物的制备方法

Also Published As

Publication number Publication date
ES2936819T3 (es) 2023-03-22
EP3419983B1 (en) 2022-10-26
AR107712A1 (es) 2018-05-23
US20170247404A1 (en) 2017-08-31
US10112967B2 (en) 2018-10-30
EP3419983A1 (en) 2019-01-02
WO2017144423A1 (en) 2017-08-31

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