ITMI20071267A1 - Uso di coniugati dell'acido ialuronico nel trattamento locale di malattie cutanee iperproliferative - Google Patents

Uso di coniugati dell'acido ialuronico nel trattamento locale di malattie cutanee iperproliferative

Info

Publication number
ITMI20071267A1
ITMI20071267A1 IT001267A ITMI20071267A ITMI20071267A1 IT MI20071267 A1 ITMI20071267 A1 IT MI20071267A1 IT 001267 A IT001267 A IT 001267A IT MI20071267 A ITMI20071267 A IT MI20071267A IT MI20071267 A1 ITMI20071267 A1 IT MI20071267A1
Authority
IT
Italy
Prior art keywords
conjugates
hyaluronic acid
skin diseases
local treatment
hyperproliferative skin
Prior art date
Application number
IT001267A
Other languages
English (en)
Inventor
Susy Panfilo
Davide Renier
Original Assignee
Fidia Farmaceutici
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici filed Critical Fidia Farmaceutici
Priority to IT001267A priority Critical patent/ITMI20071267A1/it
Priority to AU2008269431A priority patent/AU2008269431B2/en
Priority to EP08776311A priority patent/EP2167134B1/en
Priority to ES08776311T priority patent/ES2394127T3/es
Priority to US12/666,286 priority patent/US9283284B2/en
Priority to JP2010512804A priority patent/JP2010530869A/ja
Priority to CA2692191A priority patent/CA2692191C/en
Priority to PCT/IB2008/001706 priority patent/WO2009001209A1/en
Priority to PT87763116T priority patent/PT2167134E/pt
Priority to CN2008801013571A priority patent/CN101835495B/zh
Publication of ITMI20071267A1 publication Critical patent/ITMI20071267A1/it
Priority to IL202875A priority patent/IL202875A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6903Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6955Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a plaster, a bandage, a dressing or a patch
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT001267A 2007-06-22 2007-06-22 Uso di coniugati dell'acido ialuronico nel trattamento locale di malattie cutanee iperproliferative ITMI20071267A1 (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT001267A ITMI20071267A1 (it) 2007-06-22 2007-06-22 Uso di coniugati dell'acido ialuronico nel trattamento locale di malattie cutanee iperproliferative
JP2010512804A JP2010530869A (ja) 2007-06-22 2008-06-19 過剰増殖性皮膚疾患の局所治療におけるヒアルロン酸のコンジュゲートの使用
EP08776311A EP2167134B1 (en) 2007-06-22 2008-06-19 Use of conjugates of hyaluronic acid in the local treatment of hyperproliferative skin diseases
ES08776311T ES2394127T3 (es) 2007-06-22 2008-06-19 Uso de conjugados del ácido hialurónico en el tratamiento local de enfermedades hiperproliferativas de la piel
US12/666,286 US9283284B2 (en) 2007-06-22 2008-06-19 Use of conjugates of hyaluronic acid in the local treatment of hyperproliferative skin diseases
AU2008269431A AU2008269431B2 (en) 2007-06-22 2008-06-19 Use of conjugates of hyaluronic acid in the local treatment of hyperproliferative skin diseases
CA2692191A CA2692191C (en) 2007-06-22 2008-06-19 Use of conjugates of hyaluronic acid in the local treatment of hyperproliferative skin diseases
PCT/IB2008/001706 WO2009001209A1 (en) 2007-06-22 2008-06-19 Use of conjugates of hyaluronic acid in the local treatment of hyperproliferative skin diseases
PT87763116T PT2167134E (pt) 2007-06-22 2008-06-19 Uso de conjugados de ácido hialurónico no tratamento local de doenças de pele hiperproliferativas
CN2008801013571A CN101835495B (zh) 2007-06-22 2008-06-19 透明质酸结合物在局部治疗过度增殖皮肤病中的应用
IL202875A IL202875A (en) 2007-06-22 2009-12-21 Use of Hyaluronic Acid Conjugates or History and Anti-Malignant Medications for Topical Treatment of Actinic Radiation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001267A ITMI20071267A1 (it) 2007-06-22 2007-06-22 Uso di coniugati dell'acido ialuronico nel trattamento locale di malattie cutanee iperproliferative

Publications (1)

Publication Number Publication Date
ITMI20071267A1 true ITMI20071267A1 (it) 2008-12-23

Family

ID=39938375

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001267A ITMI20071267A1 (it) 2007-06-22 2007-06-22 Uso di coniugati dell'acido ialuronico nel trattamento locale di malattie cutanee iperproliferative

Country Status (11)

Country Link
US (1) US9283284B2 (it)
EP (1) EP2167134B1 (it)
JP (1) JP2010530869A (it)
CN (1) CN101835495B (it)
AU (1) AU2008269431B2 (it)
CA (1) CA2692191C (it)
ES (1) ES2394127T3 (it)
IL (1) IL202875A (it)
IT (1) ITMI20071267A1 (it)
PT (1) PT2167134E (it)
WO (1) WO2009001209A1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1399351B1 (it) 2009-06-16 2013-04-16 Fidia Farmaceutici Procedimento per la sintesi di coniugati di glicosamminoglicani (gag) con molecole biologicamente attive, coniugati polimerici e usi relativi
WO2016071365A1 (en) 2014-11-03 2016-05-12 Spherium Biomed, S.L. Topical pharmaceutical compositions of paclitaxel
WO2016191850A1 (en) * 2015-05-29 2016-12-08 Aluron Biopharma Inc. Cross-linked hyaluronic acid for drug delivery and pharmaceutical preparation using same
BR112018005200A2 (pt) 2015-09-16 2018-10-09 Dfb Soria Llc liberação de nanopartículas de fármaco e métodos de uso dos mesmos
CA3056395C (en) 2017-03-15 2022-06-28 Dfb Soria, Llc Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes
WO2018170207A1 (en) * 2017-03-15 2018-09-20 Dfb Soria, Llc Topical therapy for the treatment of skin keratoses using nanoparticles of taxanes
WO2019178024A1 (en) 2018-03-16 2019-09-19 Dfb Soria, Llc Topical therapy for the treatment of cervical intraepithelial neoplasia (cin) and cervical cancer using nanoparticles of taxanes
CN109078192B (zh) * 2018-08-30 2021-07-16 中山大学 一种小肠靶向吸收、生物降解的糖原衍生物、其制备方法及其负载茶多糖的纳米粒

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO169637C (no) 1983-10-11 1992-07-22 Fidia Spa Fremgangsmaate for fremstilling av terapeutisk aktive hyaluronsyre-fraksjoner
US4851521A (en) 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
IT1219587B (it) 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5910489A (en) * 1990-09-18 1999-06-08 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
CA2061703C (en) * 1992-02-20 2002-07-02 Rudolf E. Falk Formulations containing hyaluronic acid
US6103704A (en) * 1991-07-03 2000-08-15 Hyal Pharmaceutical Corporation Therapeutic methods using hyaluronic acid
IT1263393B (it) 1993-07-30 1996-08-05 Fidia Advanced Biopolymers Srl Processo per la preparazione e purificazione di acido ialuronico ad alto peso molecolare
ITPD940054A1 (it) 1994-03-23 1995-09-23 Fidia Advanced Biopolymers Srl Polisaccaridi solfatati
US6515016B2 (en) * 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
DK0971961T3 (da) 1997-04-04 2003-03-24 Fidia Advanced Biopolymers Srl N-sulfaterede hyaluronsyreforbindelser, derivater deraf og en fremgangsmåde til deres fremstilling
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US20040127470A1 (en) * 1998-12-23 2004-07-01 Pharmacia Corporation Methods and compositions for the prevention or treatment of neoplasia comprising a Cox-2 inhibitor in combination with an epidermal growth factor receptor antagonist
IT1317359B1 (it) 2000-08-31 2003-06-16 Fidia Advanced Biopolymers Srl Polisaccaridi percarbossilati, quali l'acido ialuronico, processo perla loro preparazione e loro impiego in campo farmaceutico e
IT1317358B1 (it) 2000-08-31 2003-06-16 Fidia Advanced Biopolymers Srl Derivati cross-linkati dell'acido ialuronico.
ITPD20020271A1 (it) * 2002-10-18 2004-04-19 Fidia Farmaceutici Composti chimico-farmaceutici costituiti da derivati dei taxani legati covalentemente all'acido ialuronico o ai suoi derivati.
US20070149618A1 (en) * 2004-02-17 2007-06-28 Action Medicines, S.L. Methods of use for 2,5-dihydroxybenzene sulfonic acid compounds for the treatment of cancer, rosacea and psoriasis
ITPD20050242A1 (it) * 2005-08-03 2007-02-04 Fidia Farmaceutici Bioconiugati antitumorali dell'acido ialuronico o dei suoi derivati, ottenibili per coniugazione chimica diretta o indiretta, e loro impiego in campo farmaceutico

Also Published As

Publication number Publication date
CA2692191A1 (en) 2008-12-31
JP2010530869A (ja) 2010-09-16
ES2394127T3 (es) 2013-01-22
EP2167134A1 (en) 2010-03-31
CN101835495B (zh) 2012-03-14
US20100204175A1 (en) 2010-08-12
AU2008269431B2 (en) 2013-03-07
CN101835495A (zh) 2010-09-15
US9283284B2 (en) 2016-03-15
AU2008269431A1 (en) 2008-12-31
WO2009001209A8 (en) 2009-03-26
EP2167134B1 (en) 2012-08-29
PT2167134E (pt) 2012-12-11
CA2692191C (en) 2016-01-05
IL202875A (en) 2016-02-29
WO2009001209A1 (en) 2008-12-31

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