ITMI20022745A1 - Esteri misti dell'acido ialuronico ad attivita' citostatica e prodifferenziante e procedimento per la loro produzione. - Google Patents

Esteri misti dell'acido ialuronico ad attivita' citostatica e prodifferenziante e procedimento per la loro produzione.

Info

Publication number
ITMI20022745A1
ITMI20022745A1 IT002745A ITMI20022745A ITMI20022745A1 IT MI20022745 A1 ITMI20022745 A1 IT MI20022745A1 IT 002745 A IT002745 A IT 002745A IT MI20022745 A ITMI20022745 A IT MI20022745A IT MI20022745 A1 ITMI20022745 A1 IT MI20022745A1
Authority
IT
Italy
Prior art keywords
cytostatic
procedure
production
hyaluronic acid
mixed esters
Prior art date
Application number
IT002745A
Other languages
English (en)
Inventor
Danila Coradini
Alberto Perbellini
Original Assignee
Coimex Scrl United Companies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coimex Scrl United Companies filed Critical Coimex Scrl United Companies
Priority to IT002745A priority Critical patent/ITMI20022745A1/it
Priority to EP03785916A priority patent/EP1578803A1/en
Priority to US10/540,939 priority patent/US20060074048A1/en
Priority to CA002529816A priority patent/CA2529816A1/en
Priority to AU2003294936A priority patent/AU2003294936A1/en
Priority to PCT/EP2003/014732 priority patent/WO2004056877A1/en
Publication of ITMI20022745A1 publication Critical patent/ITMI20022745A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT002745A 2002-12-23 2002-12-23 Esteri misti dell'acido ialuronico ad attivita' citostatica e prodifferenziante e procedimento per la loro produzione. ITMI20022745A1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT002745A ITMI20022745A1 (it) 2002-12-23 2002-12-23 Esteri misti dell'acido ialuronico ad attivita' citostatica e prodifferenziante e procedimento per la loro produzione.
EP03785916A EP1578803A1 (en) 2002-12-23 2003-12-22 Mixed esters of hyaluronic acid with retinoic and butyric acids
US10/540,939 US20060074048A1 (en) 2002-12-23 2003-12-22 Mixed esters of hyaluronic acid with retinoic and butyric acids
CA002529816A CA2529816A1 (en) 2002-12-23 2003-12-22 Mixed esters of hyaluronic acid with retinoic and butyric acids
AU2003294936A AU2003294936A1 (en) 2002-12-23 2003-12-22 Mixed esters of hyaluronic acid with retinoic and butyric acids
PCT/EP2003/014732 WO2004056877A1 (en) 2002-12-23 2003-12-22 Mixed esters of hyaluronic acid with retinoic and butyric acids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002745A ITMI20022745A1 (it) 2002-12-23 2002-12-23 Esteri misti dell'acido ialuronico ad attivita' citostatica e prodifferenziante e procedimento per la loro produzione.

Publications (1)

Publication Number Publication Date
ITMI20022745A1 true ITMI20022745A1 (it) 2004-06-24

Family

ID=32676860

Family Applications (1)

Application Number Title Priority Date Filing Date
IT002745A ITMI20022745A1 (it) 2002-12-23 2002-12-23 Esteri misti dell'acido ialuronico ad attivita' citostatica e prodifferenziante e procedimento per la loro produzione.

Country Status (6)

Country Link
US (1) US20060074048A1 (it)
EP (1) EP1578803A1 (it)
AU (1) AU2003294936A1 (it)
CA (1) CA2529816A1 (it)
IT (1) ITMI20022745A1 (it)
WO (1) WO2004056877A1 (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20040347A1 (it) * 2004-02-26 2004-05-26 Pharma Medical Ltd Nuovo farmaco di associazione
ZA200800901B (en) 2005-07-14 2010-05-26 Takeda San Diego Inc Histone deacetylase inhibitors
IE20060049A1 (en) * 2006-01-25 2007-08-08 Eurand Pharmaceuticals Ltd A novel drug delivery system: use of hyaluronic acid as a carrier moleclue for different classes of therapeutic active agents
CA2686558A1 (fr) * 2007-05-11 2008-12-11 Galderma Research & Development Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
ITMI20072237A1 (it) * 2007-11-27 2009-05-28 Sigea Srl Esteri misti butirrico-formico di polisaccaridi acidi, loro preparazione ed uso come dermocosmetici
CZ301555B6 (cs) 2008-11-06 2010-04-14 Cpn S. R. O. Zpusob prípravy DTPA sítovaných derivátu kyseliny hyaluronové a jejich modifikace
CZ304654B6 (cs) 2012-11-27 2014-08-20 Contipro Biotech S.R.O. Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití
US10618982B2 (en) * 2015-01-13 2020-04-14 Bmg Pharma S.P.A. Process in water for the preparation of butyric esters of hyaluronic acid sodium salt
MA41912A (fr) * 2015-04-07 2018-02-13 Hyalblue S R L Esters de glycosaminoglycane, procédés pour leur préparation et leur utilisation dans des formulations à usage ophtalmique
CN105418803A (zh) * 2015-12-30 2016-03-23 山东天晟生物科技有限公司 一种透明质酸的酯化方法
CN111253504A (zh) * 2020-03-19 2020-06-09 上海缓释新材料科技有限公司 一种无毒副作用的维生素a衍生物及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2282596B (en) * 1993-10-06 1998-04-15 Ciba Geigy Ag Water-soluble retinoids
IT1286510B1 (it) * 1996-11-29 1998-07-15 Cooperativa Centro Ricerche Po Esteri butirrici ad attivita' antiproliferativa e composizioni farmaceutiche che li contengono
ITTS20010017A1 (it) * 2001-07-17 2003-01-17 Ct Ricerche Polytech Soc Coop Esteri polisaccaridici di acido retinoico.

Also Published As

Publication number Publication date
EP1578803A1 (en) 2005-09-28
WO2004056877A1 (en) 2004-07-08
CA2529816A1 (en) 2004-07-08
US20060074048A1 (en) 2006-04-06
AU2003294936A1 (en) 2004-07-14

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