IT8819234A0 - Procedimento per la risoluzione ottica di un racemo. - Google Patents

Procedimento per la risoluzione ottica di un racemo.

Info

Publication number
IT8819234A0
IT8819234A0 IT8819234A IT1923488A IT8819234A0 IT 8819234 A0 IT8819234 A0 IT 8819234A0 IT 8819234 A IT8819234 A IT 8819234A IT 1923488 A IT1923488 A IT 1923488A IT 8819234 A0 IT8819234 A0 IT 8819234A0
Authority
IT
Italy
Prior art keywords
raceme
procedure
optical resolution
resolution
optical
Prior art date
Application number
IT8819234A
Other languages
English (en)
Other versions
IT1217988B (it
Inventor
Fulvio L Piselli
Original Assignee
Chimica Profarmaco Spa Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chimica Profarmaco Spa Ind filed Critical Chimica Profarmaco Spa Ind
Publication of IT8819234A0 publication Critical patent/IT8819234A0/it
Priority to IT19234/88A priority Critical patent/IT1217988B/it
Priority to DE68914480T priority patent/DE68914480T2/de
Priority to ES89100551T priority patent/ES2061737T3/es
Priority to EP89100551A priority patent/EP0325965B1/en
Priority to AT89100551T priority patent/ATE104274T1/de
Priority to US07/297,993 priority patent/US4931587A/en
Priority to JP1014941A priority patent/JP2619280B2/ja
Priority to CA000589257A priority patent/CA1338034C/en
Application granted granted Critical
Publication of IT1217988B publication Critical patent/IT1217988B/it
Priority to US07/527,029 priority patent/US5013834A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
  • Eye Examination Apparatus (AREA)
  • Control Of Indicators Other Than Cathode Ray Tubes (AREA)
IT19234/88A 1988-01-28 1988-01-28 Procedimento per la risoluzione ottica di un pacemo IT1217988B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT19234/88A IT1217988B (it) 1988-01-28 1988-01-28 Procedimento per la risoluzione ottica di un pacemo
AT89100551T ATE104274T1 (de) 1988-01-28 1989-01-13 Verfahren zur optischen spaltung einer rakemischen saeure.
ES89100551T ES2061737T3 (es) 1988-01-28 1989-01-13 Procedimiento para la resolucion optica de un acido racemico.
EP89100551A EP0325965B1 (en) 1988-01-28 1989-01-13 A process for the optical resolution of a racemic acid
DE68914480T DE68914480T2 (de) 1988-01-28 1989-01-13 Verfahren zur optischen Spaltung einer rakemischen Säure.
US07/297,993 US4931587A (en) 1988-01-28 1989-01-17 Process for the optical resolution of a racemic acid
JP1014941A JP2619280B2 (ja) 1988-01-28 1989-01-24 ラセミ酸の光学的分割方法
CA000589257A CA1338034C (en) 1988-01-28 1989-01-26 Process for the optical resolution of a racemic acid
US07/527,029 US5013834A (en) 1988-01-28 1990-05-21 Process for the preparation of an optically active benzothiazepinone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19234/88A IT1217988B (it) 1988-01-28 1988-01-28 Procedimento per la risoluzione ottica di un pacemo

Publications (2)

Publication Number Publication Date
IT8819234A0 true IT8819234A0 (it) 1988-01-28
IT1217988B IT1217988B (it) 1990-03-30

Family

ID=11155988

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19234/88A IT1217988B (it) 1988-01-28 1988-01-28 Procedimento per la risoluzione ottica di un pacemo

Country Status (8)

Country Link
US (2) US4931587A (it)
EP (1) EP0325965B1 (it)
JP (1) JP2619280B2 (it)
AT (1) ATE104274T1 (it)
CA (1) CA1338034C (it)
DE (1) DE68914480T2 (it)
ES (1) ES2061737T3 (it)
IT (1) IT1217988B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE93516T1 (de) * 1989-06-30 1993-09-15 Richter Gedeon Vegyeszet Verfahren zur resolution von threo-3-((2aminophenyl)-thio>-2-hydroxy-3-(4-methoxyphenyl)propions|ure.
IT1234387B (it) * 1989-07-12 1992-05-18 Zambon Spa Processo di purificazione di intermedi utili nella preparazione del diltiazem
IT1232306B (it) * 1989-07-27 1992-01-28 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione del diltiazem
US4963671A (en) * 1989-11-20 1990-10-16 E. R. Squibb & Sons, Inc. Process for resolving chiral intermediates used in making calcium channel blockers
IT1237785B (it) * 1989-11-23 1993-06-17 F I S Fabbrica Italiana Sint Procedimento per la risoluzione ottica dell'acido treo-2-idrossi-3- (2'-ammino feniltio)-3-(4"-metossifenil) propionico
IT1240651B (it) * 1990-05-17 1993-12-17 Zambon Spa Processo per la risoluzione di derivati glicidici
MX9101206A (es) * 1990-09-21 1992-05-04 Smithkline Beecham Corp Cristalizacion de isomeros opticos de antagonistas de leucrotieno
DK0584108T3 (da) 1991-05-13 2000-10-09 Boots Co Plc Farmaceutisk præparat omfattende ibuprofensalt
US5214201A (en) * 1991-12-12 1993-05-25 Smithkline Beecham Corporation Crystallization of optical isomers of leukotriene antagonists
US5278337A (en) * 1992-10-14 1994-01-11 Ethyl Corporation Enantiomeric resolution of aryl-substituted aliphatic carboxylic acids
US5248813A (en) * 1992-10-14 1993-09-28 Ethyl Corporation Enantiomeric resolution
US5256816A (en) * 1992-10-14 1993-10-26 Ethyl Corporation Enantiomeric resolution
US5260482A (en) * 1992-10-14 1993-11-09 Ethyl Corporation Enantiomeric resolution
US5442117A (en) * 1993-12-13 1995-08-15 Albemarle Corporation Enantiomeric resolution
US6130352A (en) * 1995-01-27 2000-10-10 Council Of Scientific & Industrial Research Method for producing (+) (2S,3S)-3-(2-aminophenylthio)-2-hydroxy-3(4'-methoxyphenyl)-propionic acid
IT1274472B (it) * 1995-05-11 1997-07-17 Fabbrica Italiana Sintetici Spa Procedimento per la preparazione del sale di cicloesilammina dell'acido (+)-treo-2-idrossi-3-(2'-amminofeniltio)-3- (4"-metossifenil)-propionico e del suo antipodo(-)
DE778272T1 (de) * 1995-12-05 1997-11-20 Tanabe Seiyaku Co Optisch aktive Benzothiazepinderivate und Verfahren zu ihrer Herstellung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2940998A (en) * 1953-10-15 1960-06-14 Ajinomoto Kk Process for resolution of racemic glutamic acid and salts thereof
US3158648A (en) * 1962-04-09 1964-11-24 Merck & Co Inc Direct resolution of alpha-methyl-3, 4-dihydroxyphenylalanine
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
JPS57136581A (en) * 1981-02-18 1982-08-23 Nippon Kayaku Co Ltd Preparation of 1,5-benzothiazepin derivative
SE449611B (sv) * 1982-07-09 1987-05-11 Tanabe Seiyaku Co Sett att framstella 1,5-bensotiazepinderivat

Also Published As

Publication number Publication date
ATE104274T1 (de) 1994-04-15
EP0325965A3 (en) 1990-10-31
IT1217988B (it) 1990-03-30
ES2061737T3 (es) 1994-12-16
JPH021466A (ja) 1990-01-05
CA1338034C (en) 1996-02-06
EP0325965B1 (en) 1994-04-13
EP0325965A2 (en) 1989-08-02
DE68914480D1 (de) 1994-05-19
DE68914480T2 (de) 1994-08-11
US4931587A (en) 1990-06-05
JP2619280B2 (ja) 1997-06-11
US5013834A (en) 1991-05-07

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940128